CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
TCOF1	6949	Treacher Collins-Franceschetti syndrome 1	5	MFD1; TCS1; treacle

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
20089989	2010	Cell line : - Source : VU University Medical Center, Amsterdam, Netherlands. Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : -	Biochemical isolation to nano-LC-MS/MS analysis	Unknown	-	-

Gene Details

Chromosome: 5; NC_000005.9 (149737202..149779871)
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Gene Type	protein coding
Gene Family	-
Description	This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
Chromosome	5
Location	5q32
Start	150357639
End	150400308
Strand	+
Gene Sequence	>gi\|568815593:150357639-150400308 Homo sapiens chromosome 5, GRCh38.p2 Primary Assembly GAAAGAGGAGCCGGAAGTGTGGCGCGCGAGGTCTAAGGGCGCGAGGGAAGTGGCGGGCGGGGACTAAGGC GGGGCGTGCAGGTAGCCGGCCGGCCGGGGGTCGCGGGTATGGCCGAGGCCAGGAAGCGGCGGGAGCTACT TCCCCTGATCTACCACCATCTGCTGCGGGCTGGCTATGTGCGTGCGGCGCGGGAAGTGAAGGAGCAGAGC GGCCAGGTAAGCGTTCGTGGGCCGTGTGCGAGGGCCGCGTGCAAGATGTGGAGATCAGCGGCCCGCGGCC CGCGCCCCGTCCCCAGGCGACCCGGCAGGCGCCCGGAGCCGGGTCCCGCAGTGCTCGACGGCGCGGCCAG GGGTACCGGAGGAGCCGCAATCTCTGCCTTCCCACTGCGACTTCAGTTCCCCTGGGCCTCACTTTCCTCA TCCGGGCAGTGGGTTGGGCCAGAAAGTGTGCTCGCAGGGGCCGAACTTTGTAATTCCCGCTTCCCTTACC TCCACGCCCTTCCTGGTAGCGGGTATTTTAAGTTTCCTAAGTCTCCCGCCACGTGGCTAGGCTCTGCGCG GCCCCCCCTGGGGCAAGGAGGTTGCTGCGAGTCTCGGGGGTGGATTGCGACCAGCCCCTCGGGGGAGCGC CTGGAAAAGGGACCCTACAGCCTCTTAGTTGAGCTGGAACTCAGGCCTTTAGCGATTGTCTGTACTGAGA CGGTCAGCTTTGGTACTCGAACTCGTGGTACAGTCATTTCTTACTTGATTAATTCAACTGTTAATCCGGT ACTCAGGGTGCTTCCTGGTGTTCGAATGGTGAGCACCATCTCTCAGCCCTCCTGGAGCTTACACTCTAGT AAGGTAGACAAATCAAAGAATCACAAAAGTGACTATATGCTTAGCACCGCAATAAGTGTTAAGAATGAGA GGGATGGGCCGGGCACGGTAGCTCACGCCTGTAATCCCAGCACTTAGGGAGGCCGAGACTAGCGGATCAC CTGAGGTCAGAAGTTCGAGACCAGCCTGGCCAACATGGTGAAACACCGTTTCTACTAAAAATACAAAAAT TAGCTGGGCATGTTGGCGCACGCCTGTAATCCTGGCTACTCATGTGGCTGAGGCACAAGAATTGCTTGAA CCCGGGAGGCAGAGGTTGCAATGAGTCAAGATCGTGCCACTGCACTCCAGCCTGGGCGATAAAGCGAGAC TCTGCCTCAAAAAAAAAAGAGAGATGGATGGCAGATTGCCCTGGTCAGGAATAGCTGAGGTGTAAATGCC TTGTGGTGGGAGGGAACTTGTGTACACACTGGCCTGGAGAAAGTCCACTCTCTTGAGCCCAGGAATTTGA GGATACAGTATGAGCCATGATCATGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACACTGTCTCAAA AAAAAATTTTTTTTAAGTCCATAGCAGGCCAGGTACGGTAGCTCACGCCTGTAATCCCAGCACTTTGGGA GGCCGAGGCAGGCGGATCACTTGAGGCCAGGAGTTCAAAACCAGCCTGACCGACATGGTGAAACCCTGTC TCTACTAAAAATGCAAAAATTAGCCATGCATGGTGGCATGCACCTGTAGTCCCAGTTACTCGGGAGGCTG AGTCAGGAGAATCACTTGAACCCAGGAGGCAGAGGTTGCACTGAGCTGAGACTGAGCCACTGCACTCCAT CCTGGGTGACAAGGCGAGACTCCATCTCAAAAAAAAAAAAAACGTCCATAGTGGCTGAAGTGTGAAGTAC AAGGGCCAGATGCCCCTGGGGAGATGGAGGCAGGGGCTGGCTGGAGTGGTCTGGTGGGCAGTTTGATCTT CCTTGGAAGAGCAGTGGTAAACCAATGGAGAGTTTTGAACTGGTGAGACAGTATCCTAAGTAGTCAGATC CCTTTGCCCTGTGGTGTAGGCTCTGCTCCTAATGCTTGCTCTCAGAACCTCCTGGAGGGACTAAAGGGTG ATGGGCCCTAAGACGTTATGTATGCTTTTCCCAGTTTCTCTGAACCTCACTTGCTCTTCCTACCGCAGCT ATGGTACTTCACAGATAAGGGGAGCAAGAGATAGTACCCATCTTCATTGGAGCAAAATATCCTGCCGTCA TGGAGCACACATTCTAGTAGGAGCAGACAGGTGACAAATAGAAAAAGTTTAATAAGTTAATGATATAGTA TATCCAATGATAGTTGGTGCTTGCTATAAAAGGCAGGCAAGGGGGATAAGGGATGTCAGACTTCGATTAT AAGTAGGGTAGTCAAGGAAGTCTCATTGAGAAGGTGTCATTTGGGCAGAGACCTGAAGGAAATGAGGGAG TGAGCTGTGTAGTTAACAGGGGAGAGAACATTCCAGACAAGAAGAATAGCAAGGCCGCGTTAGAGGCAGG GTGGCCTGACACATTTGAGGACAGCAAGGAGGACACTTTGCCTGAGGTGGAGCAGAGGGAAACTGACTCT TGAAATCTTAGTGTTACCGGCTCACTGCTGGGCACTGACAGATGGTCTTGTTCAAACCAGATAGCAGCCT GCAAGGTAGGTATCGCTGTTGTCCCCATGTTAAGAAGAAATCTGAAGTTCGAAGACGTGACGAGATTAGT TCAGTCCACCCGTGCCCCACATTGCTTAGCCTCATTAGAGTACTTGATATCCTGGCTTATTGACATTTAC AGAGACATTGGGCCCTCTGGCCTCTGCTCCAAAGGCCTGGATTCCACCTGGTTCCCTCTGCTTCCACCAA GGGACTGGTACCATTTGGGCCCAGTCTTCTCCCAGCAGACTAGTAGACTGTGGTCATGCCACCTGGATGC CTCAGGTGTCTGGGCTGTGATTCGTGCTTTGGGAAGATTGGCTGGCCACGTCTTTGAAAGCTTTTTTAAA GGTCAAAGGTGGGGAAAACCCTGTCTCATGGCCTCTAGGCATGGATAGTGCCAGAGAGGCTGGGAGCTGG ATGAATGCTAGCTTGGAACATTCCACCTCTGGCCTTTCAAAGGGGTTGTCTAAAAAGGTTTTAGTTGGGA TTGGTTGTTCTTCTTGTCTCTGGAAGGTTTGGGACAGAACTGGCAGGGCCAAGCAGACATACTTCCCAGA GCAAAAAGACCCTCTTTTTTTTTTTTTTTTTTTTTAAAGAAAGGGTCTTGCTCTGTTGCCCAGGCTGGAG TGCGGTGGCACAAGCATGGCTCACTGCAGCCTCGATATCCTGGGCTCAAGTGATCCTCCCACCTCAGCCT CCTGAGTAGCCGGGACCACCAGTGCATGCCACCATTCTCAGCTAATTTTTAAATTTTTTTATAGAGACAG TCTCACTATGTTGCCCAGACTGGTCTTGAACTCCTGGGCTCAAGTGATCTTCCTGCCTCAGCCTCCCAAA GTGCTGAGATTACAGGTATGAGCCACCATGCCCAGCCAAAAAGACCCTCTTCTGAACCACCTGTCTATAC AAGTCATGAGTTTGGGGAGATCTGGGCCCAAGAAGGATCCTTACTGTGCTGGGGATTAATTGTGGCTTTC TCTTTACCTCTCTGCAGAAGTGTTTCCTGGCTCAGCCCGTAACCCTTCTGGACATCTATACACACTGGCA ACAGTAAGTGGTGGGGCCTATAGGGTGGAGTAGGGACGGACACCCCAAGCAACTCAGCTTGGAATAAGCT GGGATACCTATCTGGTCTAAGATCTGTCCCCATAGCCCACTGTGGACACCATTGTTGCCTCCAGAAAGCC AGCTCACATCACATGGATGGGTATTTCTGTGTGGATATCTGGTAGTGGGAGGGGACATTGAGAGCTGTGA TCTCTTAAGAACAAGAGCTTCTCACCAGCTTGTCAGTTGCTCAGCAAACGTATATTGAGCACCTCCTGAA AGCCAAGTCCTGTTCTTACTTAGTATGCAAATATTGTCACAAGTGAGACAGACATGGTTCCTTCTTTCCT GCAGCTGACATTGTAGCCAAGGAGGTAGGCATAAGTCAAAGAATGAAACAAATGAATGTTAAATTACAGT GGTAGTAAGGATTACAAAAGAGAGGAATCTGTTGCCACAGCCACATAAATGGGTAAGTCTGGCTTCATCT GGGGGTCCAGGGGAAGCTTCCCTGAGGTGATCTTTGACTTGAGAGCTATAGGAATTGGAGGAGTGAACTA TGCAGTGGGTAGAGAGTGGCAGGTGGAGTGTACCTGCCAGTGGAAATTGCTAATGCTAAGTCCTGTGGCT GGTGGACAGTACAGATGGGGCTAGGTCATCGCATGGATAGCCATGCATGGGCTGGTTATCCATGGTGAGG AATTTTGTCTTTATCCAAGAGCAGTGGGGCCATGGTAGGGTGAAAAAGTGAGGAGATTGCTCTGCACCAT GGTGAGACTGGTGGGGCCATGGTCACCATCGTCCAGGCAAGAGCTGATGGGGCTTGACACAGGGAGAACA GGGTAGAAAGTGGATTCCCAAGAATCATAGGGATGAAACCAGGGCCTGTGGATGGGTGGGAGAGGAAGTA TCTTATTGACTCCACATCTAACTTGTGTACCCATGCATAGAGCTTGAAGGGAACTCAGTTTGGAGGGGAA AGATTTCAATGACATGTTGAGTGTGAGATGCCTTTTAAACATGTAAAATTTATGTACTCTTCAAGGAAGG GGGAATCATCCAAGGATATATCAACAGAGGAATGGTTGGAAAATGGAGAGAGTAATTGTGTTCTCTTCAT GCACTGGCCTGACCACAGCTGACTAAGGGAGTGAAGGACATGCAGACATATCCCATGAGGAATGGTAGAG AGTACTGAATTGCCTTGGATGGAAAGGAGGCAGGAGAGGGGTGTGAGGGACCACTGCACATCTTTGAGGA CCAAGAATAGTGCGTTCTCTGAGGCCCCGGAGACAGAAGTGGGCCCCAAATGTACCTGCTTCAGGAAGAC AGGTTTCAGCTTCTGAATATAATGACATCAGAGCTATCTAAAAATGAGGTGGGCTAGGTGGAAGTGGTGG GCTCCCTGTCATTAGAGGTGTGTAAACAAAGGCAAAAATGGTGTGGAAGGGATTACAGCCTCTGGTGGAG AGCTAAGGTCTTTGAAAACCCTGCCAACCCTCAGTCCTCTGCTGCTAAGGAGAGCTTAGAGCACAGGGCA CAGCCCACACTTCCTCACCCTGACTTGCCCAGGTGAGTGGGTGTTATTCGTAGTACTTCCTTCCCCCAAA AAACTGCTTCAGTGAGCTACTCTGCACACTCTTCCCTGCCACTGGCCCCTTCTATGGGTGAGGGGGACAA GGACCTCAAACCCACGAAAGGCAGCCTAGCCTAGCAATTCCCTGCAGAGTTCAAACCCAGCAACTAGCTG TATGTATGACCTTGAGTGGATTTCTTGGCCTCCCTGAGTCTGTCTTCACCTATAAAATGAAAATAATGAT GGCAATTATCTCATTGCATTGTGAGGGTTAGACACAGTGCTCCATATAAAGTGCTAAAACTACCGGTTGG AGGCTCCCCGACTTCCTGCACCCGCCTCAGTATTTATTAAGCATCTACTACAACCCAGCAATATTCTTGA TATAGCTGGGAACAAACCAGAGAAAAATCCCTGCTCAACATTTTTGTTGGGGGAAAAGAGGCAGAATAAA TTGATACATGTAAAAATGAAACCTGTTTTTAACAGGAGAATCCTGACAAGTGGCTTTCCTGGGAACAAGG GACCCTACTATCACATCCCAAACCATGACAGAGCAGAGTCCATCGCAGCTGGGAAACCTGGGGCCTAGAC AGTGACTCCCTGGGATGGGGGTCAATGGGCGTGAGACTTCAAAGTCCAGGGCCTCAGCCATCTGGGTGCT TATCCTACCCATGCCCTAGACTCACTTTGCCATGAGCAAGTCACTTAGTTGTTCAGTTTTTGAGACATGT GTGAGGCACTGAGGATACTGTAGTGAGCTGCCAGCTGCCTTCCTCCCTGGGCCTTTCTGTGTAGGGGAGG AGTCTAGGAAGTAAGTAAAATAACAGGAGATAGAGAAAAGCTATGAAGAAAATGAAACAGGATCACAGGG CAGAGCATGCCTTGGAAGAGGGGCAATCTTCGAGGGCCTCTCTTGGGGGGCTACATTAAAGTTGAGACGG GAAGGACGAGGACCTGGGCAGAGTCTTCCAAGAAGGCACAGTACACACAGCATGTTCTGCAGGGGGAAGA GCCTGGGCGGTTCTGTGAGGTGCCTGCATGGGTCAGCTCCTATCACTTAAAGACTGGTAGCTGCTGCAGC TGTTATATAACATTATCCAGCATTCCTGATTATTTTAAAGACTAATCAAGAATTGTAAAAGCACTTTATG AAGTGAGTGAAAATGCAGAATACAAAATTGTGCCTATACTGTGTTTTCACCACTGTTTAGATTCTATGCA CATTGCCTTTAAGAGCTGGAAGGATGCGGGAAGGTCTGTCTAGTCAATTCTTGTGGAGTTGTTCTGTCAC CCAGTTGGTATAGACAGTCACCCTTGTCCTGCAGAACCTCAGAGCTTGGTCGGAAGCGGAAGGCAGAGGA AGATGCGGCACTGCAAGCTAAGAAAACCCGTGTGTCAGACCCCATCAGCACCTCGGAGAGCTCGGAAGAG GAGGAAGAAGCAGAAGCCGAAACCGCCAAAGCCAGTAAGAGCCTTGCAGCTTTGGGAACAGGCTATGGAA TATTGATTGTTCTAGGGTAGAGTCTACCTCCAGCTTCTTCTCTTATCACTAGAAGACCTAAAAGACCCTG GGGAGGAGATTGGGAGGGCACCACATATCTTTGGCAGTATTTGAGCCCTTCCTCCGTGCCAGGCATTATA TCTCCATGCTCTGGGGGTGCAAGGCCGAACCAAAACAACCAGATGGGCCCTTCCAGTCTCATTTGGTGTA TGGGGCCCAGGAGCTGCCCTATTACAGGCTCCCAGGTGATTCTTATTAGCTGGAAAGAAGACACACGTTC AGAAGTACTGCTGGAGGGATTTCAGAAAGCAGCTAGCGGACACATTTTCTGTGTGACCTGTGGGATGCTT TAGGAATTGCTGATCTTCATGTTCATTTAGAATTGTACCCATTAGCACTGGAACGCTGTACTGGGCACTG GTTTTACACCGTTTGCAGGAGTAACTCAGTCAAAGCTTTTATAGCCCCTTCTTCTCCTAAGGTCCCAGGG CTCCTTGTACTTTCCCCAACAGCAGCCATAACTCTACAGAGGAATTGCTGTGTCTCCTTTGCATCGTATT ATCTTCTTTTGCTTACATAGAAGACACATTTCTTAATACTTATTTTTTATTTTTCAAGACAAAGTCTTGC CATGTTGTCCAGGCTGGTCTTGAACTCCTGAGCTCAAGTGATCCTCCTGCCTTAGCCTCTTGAGTAGGTG GAATTCCATGCACATACCACCATGCCCAGCTTCCTGAGTCTGCTTTTAAAGTGTTTGAGATCATACTAGG TATATATTTTATTATTTTTTTGAGACGGGGTTTCACTCTTGTCACCCAGGCTGGAGCACAATGGCGTGAT GTCAGCTCAGGGCAACCCCCGCCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGG ACTACAGGCATGCACCACTACTGTCAGCTAATTTTGTGGGTTTTCTTTTTCTTTCTTTTTTTTTTTTTTT TTTTTAATAGAGACGGGGTTTCACAATGTTAGCCAGACTAGTCTCAGGTGATCCGCCCACCTTGGCCTCC AAAAGGGCTGGGATTACAGGCATGAGCCACTGCGCCCTGGATATATATTATATATCGCTTAATTTTACAT TATAAATGCAAAACGAGTTCACTTTGAACTGTAGAAGAGCATATAGAAGAAAACTTAAAGGTTTTTTGTT GTCCTACCCTGTTCCCTATCATTCCTAAGTGCATCTCCTCATAGGTAACCTTTAAAACTTCCTCCTTTGC CTCTATATTCATTCAAACATGTATTCTTACATGCATATATACAGACCTGCATGCTATTTGAAACACAAAT GGTAAAATTTCTTACTGATTGGCTATTTGGTATTAATCAATTTTATAAGCTGTGATAATGGAGGTGTAAT TACATTTTTTTGTTTGTTTGTTTGGGGCTTTTTTTGATATGAGGTCTTGCCATGTTGCCTAGACTGGCCT TGAACTCCTGGCCTCAAGTGATCCTCCTGCCTCAGCCTCCGGGTATGTAATTTTATTTTTTTAAAAGTCT TCACTGGGTTGGGCATGGTGGCTCACACCCACCGGTAATCCCAGCACTTTGGGAGGTCAAGGTAGAAGGA TCACTTGAGCCCAGGAGTTGGAGACCCGCCTGGGCAACATGGCAAAACCCTGTATCTACAAAAAATTTAA AATTTAGCCAGGCATGGTGGCGTGTGCTTGTAGTTTCAGCTGCCTAGGAGGCCTGAGGTGGGAGGATTAC TTGAGCCCAGGAGGTCAAGGCTACAGTGAGCCATGACTGTGCCTGCACTCCAGCCTGGGCAACAGAGCAA GACTGTCTCAAAAAAAAAAAAAAAAGGAAGAAGAGTCCTCGTTGGCATCCTGGGCAACATAGTGAGACTC CGTCTCTGCAAAAAATAAGAAAATTAGCTGGGCATGGTGGCATGCACTGGTGGTCCCAGCTACTCAGGAG GCTGAGATAGGAGAATCATGTGAGTCCAGGCATTGGAGGTTGCAGTGAGCTATGAATGTGCCACTGTACT CCAGCCTGGGCAGCAGAGCAAGACCCTGTCTCAAAAAAAATTTAAAAACGCATCCTCATTGAGAGAGAAA CATGCTGAAGTATTTGTGGGCAACGTGGTAGGATCTATGGCATTTTCTTCAAAGTAATGCTTGATGGGGA AGGGTGAGTGAGATAATACATGAGATGAAAAGATTGGTCACAAGTTGTTAATGGTTGGAGCTGCCTGGTT CTTCCTTTCTATTTACTACTTAAAAATTTTCCATAATTACAGAAAGAGAGAGATGGAGTGAAGTGCCAGG AAAAGAATTAGATCATGCCATTCATCTCAGCAACATTCTTCTTTTTTTTTTTTTTTTTTTTTTTTTTGAG ACGGAGTCTCGCTCTGTCGCCCAGGTCGGACTGCGGACTGCAGTGGCGCAATCTCGGCTCACTGCAAGCT CCGCTTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCAC CGCGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTTAGCCAGGATGGTCTCGAT CTCCTGACCTCATGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGGCCACCGCGC CCGGCCCAACATTCTTCTTAACAAAAAGAAATCTGAGATTTAAGGAGACAATACCCTGGTATAAAAGCAC TGAGAAGCTGGGTGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATCACG AGGTCAGGAGATCAAGACCATCCTAGCTAACACGGTGAAACCCCGTCTCTATTAAAAATACAAAAAATTA GCCAGGCATGGTGGTGGACGTCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATAGTGTGAACC CAGGAGGCGGAGCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGCAGGACTC TGTCCCAGTAAATAAATAAGCACTGAGAATCAGTGAATATCGATATCTAACGGGGCCCAGGTGGCATGGT TCAGCCACCTCTCCACTAAGAAGCCATTTGAATTCCAGGCAACTTTCTCTGTGGACCTGAGGCTGGCTGC CTGCCTGACCACTGCCCCTTCTTGCCGAACAGCTTTCAGGGCTACAGTGTGGTGGCCTGTGTGAATGGTG CCCATTGCAGTGTGCAGTGCCCAGTAGGCAGCAAGAATGTGGGCCAGTCCTTTTCCCTCCAGGGGCCTCC ACGTCTCATGCTGCGGGGGAGTTGGGAATCCATCAAGGATGCAGACACATAGCTTCATGTTACCATCCTC TTCTCTCTTGCTCCTGGTGGACCTGGCTGATGCATCACAGAGCTCATTCCTGCAAGTCTGGGCTCAGCCT CAGATCCTCATGCCAGCACCAGGCAGCCAATACCAATAGAATTGTTAGGTGAGATGAAACCTGTTTGCCA TTCATAGATGAGAAAAGCTCATCTGGCTCCTTTAGCAGATGTTTGTTTCTTGCAGCCCCAAGACTAGCAT CTACCAACTCCTCAGTCCTGGGGGCGGACTTGCCATCAAGCATGAAAGAAAAAGCCAAGGTGAGTGGGAC TGCCTTCCAAGCTATTGCCTATGGGATTTAAGGTGCCTGGTAGGGGACAGTCTTACATGTCAGAGAAGGA TAGGGTTGTGAGTAATTGCCCCACCTGGATTCAGAGCTCAACCTGTGTCACCAGTTGTGGGATCTTAGTC CCTTCACCTCTCTGGGCCTCAGTTTACTTTTCTATAAAGATAAGGATGATGCCTGCTGCAGTGGGCCACT GGGCACATTCTACACCTGGGGTAGGCGATTTCTTTCCTCTTTCATGCCTGCGTTCACCCGTTCACTCAAC AGATCTTGACTAATACCTGTTATGTTCCAGGCACTGTGCTAGGTGTGGAGGCACCGTAGTGATCAAGACA TCTGTGGTTCTGAAACTCTAAAAGCATTTTCCAAACTGGAAACTGCTCAAAAAACAAGGTGTCATTTTCT AATAATCCAGAAAGCAGAGTTAGATACATACATGTATAAAGAATTGTGCCTCTGCGATTGCCTGGAGCAT TAGCAACAATGTCTCAAAGTAATTATGAAGTAATGATAAGATCAACAACAAACTGCTACTTACCACTTAG TAAATAACTACCATGTCCCAAGAACTGGGATTCTGTTTTCTCAACACCTCTGGTGAGAGGAGGTGCTGTT TTTAACCTCACTTTAAAGATTGGGAAACAGATTGAAGGGGTAGTTTACCCAAACTCACACAGCTAAGAAG TGGTAAGATTGGGTTCAGATGCAAGTGGCCTGTGCTCTTAGTTCACCATGCCATACCAGATGTGTCTGTC ACTCTTGTTCTCTGTAGGCAGAGACAGAGAAAGCTGGCAAGACTGGGAATTCCATGCCACACCCTGCCAC TGGGAAGACGGTGGCCAACCTTCTTTCTGGGAAGTCTCCCAGGAAGTCAGCAGAGCCCTCAGCAAATACT ACGTTGGTCTCAGAAACTGAGGAGGAGGGCAGCGTCCCGGCCTTTGGAGCTGCTGCCAAGCCTGGTAAGA AGTCCCCACCTCTAGGAACCTAGTCCCCAGAACTTGGGCTGGTGAGGCAGGCCTAGGCATTGCTTTAAGT TCTGGGACATTTCTGGAATCAAAAGTTTGTCTCCAGGACAGCCAGGTTCCTGCATCTTAGGACTTTTCTC ATCACCTAGACGAGGGAGGGTCAGCTTACAGGGACCTGGCCTCAGGCTGAACAGCCCACCTGGTGGTTGG AGCATTTTCTGCTTTATGACTCCCTGGTGAGTTACAGGGACAACTGGCAGCTCAGAGACTAAACTGAAAG GCCTGATTTGCCTCTGTTTCCTATGTAGAGTAGACATCTGTCTGGCCTGCATCAGTGGATATGATGGTGG ATGGAGGTTCTGTAGACTGTCAGGTGCTGGTGCATATTTGTTGGGTCCCCTCACAGCCCTTCCCAGGGCC TCAGAGATGTGTGGGAACATAGGGATGGTGATGGTACCCACCTCAGAAGGGGGCTTCACAGCTCAGTGCA TGTGAGGCACACGAGGGGTGAGCGCTCAGCACCTGGCTTTGATGAGCAGCTGGTTTGTGGGGAGGTGCTG GGGAGGGGCAGGTGAGGCTGGAAAGGGAGTCCCTCAGTCCCCTCCGTGTCCGATCCTCAGGGATGGTGTC AGCGGGCCAGGCCGACAGCTCCAGCGAGGACACCTCCAGCTCCAGTGATGAGACAGACGTGGAGGTAATT GCCACCCATCCCTAGGAGTTGCCCTCTCCCAGCCTCTAACCCTTCCAGGAACCTGTCTGGGGCTTCAGAC ACCAGTGGGCCCAGATGAGTTCAGCAACTGTGGTAGGGTGACCAGGAGCTGGAAAGGCTGCAGCCGGAGA GGGGCAGGGAGAGGAGTCTGGTGCTGCTTGCTGCACTCTGAGTGTGAGATCAGCCCTGGGGGCAGGAGAG GGACACCCTCCTGCCTGTGAGACTAGACAAGCCTTCCTGGGAGAGGTGCCCTGGAGTAGGGCCTCAAAGC ACAGTGGGCTTCACTGGGAAGGGATGTGGAGGAGGCAGGGCATTCCAGACAGGAAATGGGGCAAGAACAG GGCCCAGAGGCAACAGTGTGGCTGTCGTGGTCTGGCTAGGGCTGCGGCTGCTGAGAGGGTTCTGGGCCAA CTGGTGAATGCCAGGCCTAGACACTTGGCTAGAGTTGGGCAGGACTCTTGGGTTTGTGAACTTTGACCTG GAAAAGGTCTCCACAGGTTACTTTTTATTGTGTACCTACTAAGTGGCAGACCTGGGGAATATAGTGATGA GCAGGACAGGCAGAGTTCCTGCTGCCATGGGGCAAGGGAGCGTCCCTCAGATATTTAATTGGTGATGGCT GCTATGAAGTGGAAATGTAGAGGGCCACGCAGGGCAGGAACCTGACGTTGATGAGTAGGCGTAAGCAGAA GGAATGGCATGTGCAGAGAAGGCGGCAAAGAGAGTTTGGTGCTTTTAAAGAACATTGATCTTTTTTTAAG ACAGTCTCACTGTGTCACCCAAGCTGGAGTGCAGTAGCGCGATCTTGGCTAGCTGCAACTTCCACCTCCC GGGTTCAAGCGATTGTCGTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGCACGCCACCACGCCTGG CTAATTTTTGTATTTTTTGTGGAGACAGGGTTTCACCATGTTGGCCAGGCTAGTCTCGAACTCCTGACCT CAAGTGGTCCATGTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCGCCACGCCTGGCCAAA ACCTTGATCTTTAAATGAGAGGGAGAAACCAGGCACGGTGGCTCGCACCTGTAAGTGCAGCACTCTGGGA GGCCAAGGCAGGAGGATCATTTGAGGCCAGAAGTTTGAACCCAGCCTGAGCAACATAGTGAAACCCTGTC TCTACAAGATGTTATTTTTTAAAAAAACAAATAAATTATGGGGAAAGTGACACAAGATGAAGTCCTAGGT AGACAGGGGCCAGATCTTCTGTCTGACCTTGAGGACCACCATAAGGAATTTGGGTTTTATTCTAGGGGCT GTGAGAAGCCATGCCAGCAAGGAGAGATGGCCTGATTTGCATTTAATAAGATTGCTGGCTGCAGCCTGGG TTGGAGGGCAGTGCAGAATAAAAGCAGTAAGACCATGTAGGAGACTATTGGAGTAATACTGATACTGGCA TAAGAGGCTGGGGGCTGGGAGACCAAGGTGTCCACAGTTGGAAAGATGTTTTCAAGGGAAAACCAGCACA AGTCAGGGATGAACTGATCTGGTGCCCAGGGAACTTCTCACTTTACTGTGCTGCCTGGCCCAGTAACCCT GTGAAGGTTGAAAGCTCACCCCCATCTACCCCAGGCCTTACCAAGGGCTGCCCTCCACCTTCCGTCCTCA CCCTTGCGCCCTAGATACCACCAGCTGTAAGGACATCCCTGGCTTCTGTCACCCCAGGCCTTGCCAAAGG GAAGAAGACCACTCCCAGCCCTCCATAAACACACAACCTCAATGGGCTGAGGCTGTGCAGAGCTCCAGTA GCAGACGCCCCAGAAACCCAGGGCCGCAAGGGGTCTGATGGATCTCAGAGGTAGAAGTAGGGCACTGACT GCCTGGGAAATGTCTGAATTGTGGAAGTGTAGGAAAGAGCTCACAGAGGGAAGGAATTTGCCCAAGGTGT GGCAAGCCAGTGGCAGAGGTGGTGTTCACATCCTGAACTCCTGGCCCTCAGGAGGGCTGCTGTGATCAGA TACTTGAGTTTAAGGGGCAGACAGGATGCGCTCTCCTGATTGAGATGCAAGCCCTTCTCTCAGGCCAAGC CCGGTGTGTGCCAGGTGGGAGATGAACGTAATGGTTTTGAGATCTGTTCCAAAGTCAGACAGTCCAGGGT TCCAGTGGGGCTCTGTCCCTTCATATTGATCATGAGTGATTTTACCTCTTTAAGCCTTGTGTACTTTTCT GGAAAATGGATCTAAAGCTAATAGCCGTCTCAGGGAGTTGCTTAAAAATCCAGTGACATTAGGAAAGAGC TTTATCAACTGCTGAAGCCCCTAATACAGAACCTTAGGGGGAAACAGTAATTATTATTCATTTTCTAATT CCATCCTCTTGTTCCAGGGGAAACCCTCAGTAAAACCAGCCCAGGTCAAAGCCTCATCAGTTTCTACTAA GGAGTCTCCAGCAAGAAAGGCGGCCCCAGCCCCTGGGAAGGTGGGGGATGTGACACCCCAGGTCAAAGGA GGGGCCCTGCCCCCAGCCAAGAGGGCCAAGAAGCCAGAAGAGGAGTCAGAGAGTAGTGAGGAGGGATCTG AAAGTGAGGAGGAGGCCCCTGCAGGGACACGAAGCCAGGTGAGGCCTGGAGGAGGGCTGCCCCTTGGAGG ACCTGCGGGTCCCCCAGCAGCCTGAGCACTCTGCCATGAGCACCTCTGCCACTGGAGTTGGGGAGAGGGA GGACTATGGTGTGAAGTTGAAGAGCAAGAACAGCCTGCTTCCCACAGGGGAGTCTTGCACTCCACTTTGT CTGTGACCAACTTTACCTCAGTTTCTCTGCCTAGTAAATGGGCCGCTGTCCTCGTCCCAGCCAGTCCTGC TGTGAGGGACTTGAGAAGTTTTGATTGCCTAATCCTCTGACTTCTCAGGACAAACCAGACCCTGAGCAGG CAAACACTACGTTAGCTAAAGGGAATCCAGTTCCCTTCCCCATCTGCTGGGAGTGGGCAGGGCTGCAGCC CCAAGGCCCTGGGTGTATCCCAAGGGCAAGACAGGGGGGCTGGAAAGCAATGGAAGTCAGAGCAGGAAGG AGGAAGAGTGAGGGTCACCCACCCAGCCCCAGGCCTGGGGCAGGACAAGGCGGGGGCATGCAGTAGATAA GCAGATCCCCTGCGTTAGCTGCTGGTAAATGGTAAAGAGGAAGTGGGGGACATAGGAATGGCAACTTGAA GCAGAGTGCTCTGGGCTGGCCTTGGGAGAAGGCGTCTCAGTAAAGACCAGAAGGAGGAAGCACTCTTAGG AAGGTCATTCCAGGCAGGGGCTCAGCAAGTGTCAAGGCCCTGAGGTAGAAGTAGGACTACGAATTGTGAC AAATTGTTGTTCCCACCCCATCTACAGGGAACTTCTACGCCTCGGCTGTCTATTTTGCAGTGTCTGGGGG CTACACAGTGTTGGATGGGCATCCACTTTGAGAAGGAACACAAATGTGAATTTTTTTTTTGAGACAGAGT CTTGCTCTGTTGCCCAAGCTGGAGTGCAGTAGCGGCAATCATAGCTCACTGCAGCCTCACTCCTGAGTAG CTAGGAATACAGGCACACACCACCACACCCAGCTTGTGTGTGTGTGTGTGTGTGTGTATAGACAGGGTTT CACTGTGTTTCACAAGCTGTGGACTCAAGCAGTCCTCCCACCTTGGCCTCCCAAAGTGCCGTGATTACAG ATATGAGCCACCGCACCTGGCCATAAATGTGAACTTTTATGTAAAATCTGCTTTCTCCATGTTGGCTCAA AAATTTAAAAAGGAGCTAGCCAAGCAAGACCTGTGTGGAGCAGCCTGCACTTTCTGCATGAGAAGCTTCT TAGAAGATCAGAGCTGCTGTTTTCTAGGGTTGTTGGCCCAGGGCTGAACACCCAGGGCCTTCCAGGGAAG ACAGGGCCTGCAGCCACCCTGCCAAAGCCCCAAGACAGTGCAGAGCCCCACCGAGGAGTTAGTGAAGAGG GGGCCAGGTGTGCAAACCTTGCCCCATGAGGCTGAGGGTGGGCTTCCAGGGGTCCTGCTGCTGTCCATGT GCAGAAAGTCCAGTGAGGGCCTCCCTCAGTCCCTTCCCCACTTTCAGACTGCCTCTTCATTCCTTCCCTT CCCTGGGCCTTTGCACACCCCCTCCCCACAGCCCAGTCTGATGATGCTCCCGATAAGCCAGTGCCTGTGC CTCCAGAGCTCTCTGGCCAGTGGGAGCCCAGCAGAGGACAGGCTCTAACTACCCAGTGTGCTGGGGCACC AGGGGGAACCATGTTAAGGAAGTGGTGTCTCTTAGGGAGCCAGAGACAGAGGAGGCAGTGGCTAAGTGAA ATGGAACAGGGGGCATGGAGGCTCCAGGAGTGAGAGTGTGTGAAGCTGATCGATTTTTGAGAAACCAGGA GGCCAGTGTGGCCAAAGTATCAGTCAAGGTGGGGAGTGGGGAGGGAAGCAGGGGAGGTCTTAGGAGCCTC ATTAAGGCCTCTGGACTTTATCCTAAAGGCATCACCAGAGAGTTTTCACAAGCAGGAGAGCAAGCTGCCC TTTCTTTTTCACCAGGTAAAGGCCTCTGAAAAAATTCTCCAGGTCAGAGCTGCCTCAGCCCCTGCCAAGG GGACCCCTGGGAAAGGGGCTACCCCAGCACCCCCTGGGAAGGCAGGGGCTGTAGCCTCCCAGACCAAGGC AGGGAAGCCAGAGGAGGACTCAGAGAGCAGCAGCGAGGAGTCATCTGACAGTGAGGAGGAGACGCCAGCT GCCAAGGCCCTGCTTCAGGTGAGGCCTGAGGAGGGAGACTCCATGCAGCCAGGCCCGTCCCCAGAAGGCC TTCTCAGGACTTGTTCTCCCACTCTGGGCCAGAGCCCCGGGCGTGCCTCAGACCCCAGCCCCTTACTCCC CTCTCACTGTGTGGCATCATTTGCCCTATCTGGTCTTCTGTACGTGGTGTCCTGTGTCTCCTCACACGTC CATCCTCTGGGCTGTCTCCCCTTGTCTTGTTTCTCCAGGCGAAGGCCTCAGGAAAAACCTCTCAGGTCGG AGCTGCCTCAGCCCCTGCCAAGGAGTCCCCCAGGAAAGGAGCTGCCCCAGCGCCCCCTGGGAAGACAGGG CCTGCAGTTGCCAAGGCCCAGGCGGGGAAGCGGGAGGAGGACTCGCAGAGCAGCAGCGAGGAATCGGACA GTGAGGAGGAGGCGCCTGCTCAGGTGAGGCAGAGGGGAGGGGTGGAGAGTAGCCCCATGCCTAAACCCCA GCACCTGCATGGGTGTGGCCACCTTTGCCACATCCAGCTCCTGTCTCCACACGTCCACCCTCTGGGCTCT CCCCTCATCCTGTTTCTCACTCCAGGCGAAGCCTTCAGGGAAGGCCCCCCAGGTCAGAGCCGCCTCGGCC CCTGCCAAGGAGTCCCCCAGGAAAGGGGCTGCCCCAGCACCTCCTAGGAAAACAGGGCCTGCAGCCGCCC AGGTCCAGGTGGGGAAGCAGGAGGAGGACTCAAGAAGCAGCAGCGAGGAGTCAGACAGTGACAGAGAGGC ACTGGCAGCCATGAATGCAGCTCAGGTGAGGCTGGAAGCCGCCCTGCATGGCCTGTGCCCTGCCTCAAAA GACCTCCTGTGGTTTTGACTTTTCCTCTCTGAACCTAGAGCCCTGTGCGGCTGGCTTCGTTTGCTCTCCT CCCCTCACTCACATTCTCCTTCTGGACTCCCTCCCTAATCTTGTCCTTTGTGTCTCCCAGGTGAAGCCCT TGGGGAAAAGCCCCCAGGTGAAACCTGCCTCTACCATGGGCATGGGGCCCTTGGGGAAAGGCGCCGGCCC AGTGCCACCCGGGAAGGTGGGGCCTGCAACCCCCTCAGCCCAGGTGGGGAAGTGGGAGGAGGACTCAGAG AGCAGTAGTGAGGAGTCATCAGACAGCAGTGATGGAGAGGTGCCCACAGCTGTGGCCCCGGCTCAGGTGA GGCCCCTTCCTGTAAGGCTCTTTCTTTTTCCCCCCCACTCAGAGTGGAGCTGCCTGTGGCCTCCCAACCT CACACTGGGACTCTGTCTACAATCTTAGTTTCTTAATGTCTGCACACACCTACCCTGGGCTCCCTCTCCC GATCCTGTGTATCTCACTCCAGGAAAAGTCCTTGGGGAACATCCTCCAGGCCAAACCCACCTCCAGTCCT GCCAAGGGGCCCCCTCAGAAGGCAGGGCCTGTAGCCGTCCAGGTCAAGGCTGAAAAGCCCATGGACAACT CGGAGAGCAGCGAGGAGTCATCGGACAGTGCGGACAGTGAGGAGGCACCAGCAGCCATGACTGCAGCTCA GGTGAGGCCTGGGGAAGGAGGCTGCTACATGGCCTGATCTGCCACACCACAGTCAGCACCCCCGGGGAGC TGTGCTCCCTCAGGCAGAGCATGGGTTTTGGCTGGTGGGGCAGAACAGATGGGGGACTCTGAGTTCAGGA ACCTTCTCCAGCCTTTCTTTGGTGTCCCCTCAGGCAAAACCAGCTCTGAAAATTCCTCAGACCAAGGCCT GCCCAAAGAAAACCAATACCACTGCATCTGCCAAGGTCGCCCCTGTGCGAGTGGGCACCCAAGCCCCCCG GAAAGCAGGAACTGCGACTTCTCCAGCAGGCTCATCCCCAGCTGTGGCTGGGGGCACCCAGAGACCAGCA GAGGATTCTTCAAGCAGTGAGGAATCAGATAGTGAGGAAGAGAAGACAGGTCTTGCAGTAACCGTGGGAC AGGTGAGGCCTGTGTTTTCTGGGCGGGCCTCAGGGCCGCCCCTACGTGGTCCTTTGGACTCCTGGAGACA CCTCTCTTCCCCTTGTCATCCCAGGCAAAGTCTGTGGGGAAAGGCCTCCAGGTGAAAGCAGCCTCAGTGC CTGTCAAGGGGTCCTTGGGGCAAGGGACTGCTCCAGTACTCCCTGGGAAGACGGGGCCTACAGTCACCCA GGTGAAAGCTGAAAAGCAGGAAGACTCTGAGAGCAGTGAGGAGGAATCAGACAGTGAGGAAGCAGCTGCA TCTCCAGCACAGGTGAGGCCTAGAAGGAGCAGGCCCATCCCACCCACACCTGTTCCTGAGCCAGGGCTGA GGATGGGCTTGACTGGGGGCTAGTGTTGCCTGCAGGTGTGCAGAAGCCTCAGAGGTAGCCTCAACACAGC TTCCTTCCCTATCTTTCACTCCATGTCTCCTCTGCCCATCAGAGCTCCAGGGTCTCTGTCTTGTTTGCCT TTTGAGGTCCTCCTGCTGATTGATTCCCTGTGGTTTTCACAAGCTCTGGAGTTCCCACCCTGCCAGGTGC TGCCCTTGTCTGGGGTTGCTGAGGCGCTGTTCCTCAGGGAAGTCCTGTCTCTGTGGAGCATGGACATGCT CCTGCAGTGTGGAGCGATGGGGTTGAGATAGAGGGTGTGAGCCTGGGCTGCGCAGCATGACAGGTGAGAG CATCTAGGCCTTTTACAGGAGGTGGCAGCATCTGAGCCATGGGCTGAAAGAGTTGGCCAGGTGAAATGGG CAGGGAGAGTGTTCCAGGCAGAGGAAGCAGTCTGTGCGAGGCCAGGGAATGAGAGAGTGCCTGGCTTGGG TGCCTTGCCACAGGCGGCACATTGTGGTGGGATGGCTGGCAGTTGTTTAGAGCCAGACCGCCTGGGTTCA AGTTTCAGCTCCACAGCCTGGCAAGTGCTGTAAGCCCTCAGAGCCCTTACTCTCCTATAAACAGGAAATC AGCCCTCACAGGTTTGGGTGAGAATTTAGGTGAGATCTCACCTGCTACACCCAGCAAGGGAGCTGCACAC AGCAAGTTGTCTCTGTCACCCTGACGATGGGCCAGGCTAATGTGGAACAGATCAGGAGTGAGGTCTCCAA GCCTGGAAGAGCTGAGAGAAGATGGCTCACTCCCTGCACTCACCCACCCACTGTTTATTATTTTTAATTG TCGCTCTGTTTTTTTCTGTAACCACTCAGAAATTAGTCATTTCTTTTTTCTCTGTACCAGAGCACACATT TCTACTGATTTTTTTTTGTCCTCCTCTCGTTGACTTGTGGGACCTCAGGGCTCTAGAATTCCTCCATTGA GGTTTTTAAGCTCTGCAGGGGCCCCTTCCAGAGCCGCCTCTACTCTTTCCCAAGCTGCAGGCACATTCCA GACCCAATGCCTTACAGAGTTTCATTATGCAGCTCACTTAAATATTTGTCTTCCCTTCTGAGCCTCCCAC CTGTACCATGAGGTGGGTGTTTTATTTTTATTTTTTGAACCATGGGCTATTTTGAAGTAAGCCGTTTAAT TTCCAAATATCTGGGATTACCCAGGTTTCTTTTTGTTGATTTCTAATTTAGTCACATTGTGGTTGGAGAA CATATTTTGTATGATTTAAATCCTTTTTTGTGTATTGAGACTTGTTAGGTCAAGTCAGTCTTGTGTCTTG TTTCTTGTGGAAAACATGGCTCCCCTCTGGAGGATTTACGTGCTCTACTGATGAGCACCTCGGCCTGAGT CATACTTGGTCCACACTGTAGGGAATCTTCTTGAAGTCCTGATTCTTCACCTCATTTGACCTCATGTGTT TGAGGAATGCTGGGGGATGGGGTTGTTTTCTGACACTGACCAGATGCCATCCCTGAGTGAGGCAGGGGCC TTGAGATGCTGCCAGAGTCCTCATTCTGTTTCACATTAGGCTTGCTGTCACTCCTGTTAAGGATCTCACT CTGGGAATTTCCCTTTTTTTTTGTTCTCCTTCTATTTGTTGGAATCCCTGACAGGCCTTTTGGGGGTTCT CTGGATATCGGTTAAGGCTAGATTAAGCTGAAGAAAACCTTAAACAACAAGTATCTTGTTCTGCCGTGGC TGCTTGAGCTCCAGCTCTGACCTCAGCATTCCATCTAGCCTGGAGGAGGAAGAGACATGTTTCTGACCTT TTATGGCACTCAACTTACATCCTATGAGCCAGAATTTAATGACATTGCCACCTAGCTGAAAGGGAGCCTG GAAAACATCTGTTTTAGGTAGTCTTGTGCTTAGCTAATGCTAAGGAAGGCACGCACAATGAGTTTGAGTG TTTATTATGTTCCAGACATCATGTTAAACTCTGAATCTCCTATTTAGTCTTCATCATAACCCGTAGGTGG GCCTTATTATTATCTCCATTTGATAGAGGACTGAACTGAGGCCCAGTGAGATCAAGTGATGAGCTCAGGT TCACACGCCTATTGCATGGAGGAGCCAGAATCCAGACTCGGGCTCCAGCTCCAGAGTCTGTATTCTTGGC TAGCTGCTTTACTCAATCTCACCTTCTCCCTCCTTAATTCCCTTTTCTCCACTCAGGTGAAAACCTCAGT AAAGAAAACCCAGGCCAAAGCCAACCCAGCTGCCGCCAGAGCACCTTCAGCAAAAGGGACAATTTCAGCC CCTGGAAAAGTTGTCACTGCAGCTGCTCAAGCCAAGCAGAGGTCTCCATCCAAGGCAAGTGGGGCCAGAA GCCACAGGAGGTGTGGAGGGTTGGGGTAGAGAGGAGGACCAGTCACTGAGCCCAGCCAGGAGAAGGTGCG TGCATGGGCAGGCCACCCACCCAGAGTTGTGCCATAGTGGGGAGTGGGACCTGAAAGGAATCACTTTTGC CTCCAATACTATTATCCCCCTGCAATTCAGGTGAAGCCACCAGTGAGAAACCCCCAGAACAGTACCGTCT TGGCGAGGGGCCCAGCATCTGTGCCATCTGTGGGGAAGGCCGTGGCTACAGCAGCTCAGGCCCAGACAGG GCCAGAGGAGGACTCAGGGAGCAGTGAGGAGGAGTCAGACAGTGAGGAGGAGGCGGAGACGCTGGCTCAG GTGAGGGGGAGGGAATGGAGATCATCCCCTACATGGGATGTAACACCTTTGCCACATCCAGCTCCTGTCT TCTCACACGTCCACCCTCCAGGCTCTCTCCTCTCATCCTGTTTCTCCCTCCAGGTGAAGCCTTCAGGGAA GACCCACCAGATCAGAGCTGCCTTGGCTCCTGCCAAGGAGTCCCCCAGGAAAGGGGCTGCCCCAACACCT CCTGGGAAGACAGGGCCTTCGGCTGCCCAGGCAGGGAAGCAGGATGACTCAGGGAGCAGCAGCGAGGAAT CAGACAGTGATGGGGAGGCACCGGCAGCTGTGACCTCTGCCCAGGTAAGACTTGCCAGGCCTCTGAGCCA CCAACACTCACTCCTCAGAACGGGGGTATAGGGCTGGGCGTGGTGGCTCACACCTGTAATCCTAGCACTT TGGGAGGCCGAGGCAGATGTATCACTTGAGGTCAGGGGTTCAAGACCAGCCTGGCCAACATGGTGAAACC CCGTCTCTACTAAAAATATAAAAATTAGCTGGGCATGGTGGCGGGTGCCTGTAATCCCAGCTACTCGGGA GGCTGAGGCAGGAGAATCCCTAGAACCTGGGAGGCGGAGGCTGCAGCAAGCCAAGATCATGCCACTGCAC TCCAGCCTGGGTGATGAGAGTGAGACTGTCTCAAAAAAAAAAAAAAAGAAAAAAAAGAAAAGTGAAAAAC CAGGGTTTAGGGCCAGGTAAGGAAAAGAAAGGAAGGCCAGGTTAAGGCTTAAGGCTCCAGTTCCACCATG CCCTCCTCCGTCTGCTGTCATCCACATCTCCTTAGGTAAAACCTGCTACTAAAACCCCCCAAACGAAGAC TTCCGTAGCTAAAAGTGTCCTGGGTCTATATCTAGGTCGAGGTCTCCACCAGCTCTATAAGCTAGGCCAG TATTTCCCACCAAGGCATATGAGACCAAGAATCTACATGTTAGTTATTGTGCATACGTTAACGTTATACA AAATGACTCTCCCTGTCAGAGTCCCAGGGAAGCTTGGAGTGTGGCACAGGTCCCCCTGAGGTCCTGGAGA GATGGAGGAAGTCTCATCCTGCACCTTGGCCCGGAGCCTCACATAGGCAGGCGCATCTTCTCAGGCAGGG CTTGTCTAGCTTAGTGCAAAGCCTGGACCCTGGAGAGTGGGGAGAAAGAAAATCTGAACAATTCCCTCTG TCTGCTTGCAGAAGATAGCAGGGCTTGCTACATCCTACAGAAGTGTAGGATGACAAACTCCAGCACTGCC AAGGCACAGGTGTGTGATGGAAATGACTGATGCAGGCCTGGCAGGAATGATAGATGTCGGCCGGGTGCGG TGGCTCAAGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCGGATCATGAGGTCAGGAGTTCGAGA CCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAAAATACAAAAATTAGCCAGGCGTGATGGCA GGCGTCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAAGCAGAGGTTG CAGTGAGCCAAGATCATGCCATTGCTTTGCACTCCAGTCTGGGCAACAGAGTGAGACTCTGTCACAAAAA TAAAAAAAAGAGATGATAAATGTCAGGAGAGATGGTAGATAGTGGTAGCAAGTAGGGCAGACCGGAGAGC CCTTGCCCCATCCAGAGGGGCAGTTCTTATCAGCTTCAGCCAGTCATGACTGTGGAGATGGACCTTCTGT GTGGCCAGGTCTTCCATTTCTTAAGGGAAGCTGGAAGTCCCTGTGCCAGGCCAAGCTCCATAACCTCTTA GATTTGTTTTCTTCATGAGTAAAACAAGCACTGAGATGAATGCTCCCTAGCCCTAACCTCTGCCTTTGAT ACACCAAACCAACAATTACTGGGGGTGAAAGACATTGGCCCCACCCTCAAGGAGCTCACAGTCTGTGGGG CAAGACAGGTGACCGGATTATCGCAGACTATGCTAGTGGTGCTGACAGCTGAAAGAGCAGGTCTCTGAGA GGCCAGAAAAGGAGGAGATGATTGAGCTGAACCTGAAGGATGACCAGGCACAAAAGTGGAGAAGGCCCCT CAGTGTGTGCAGAGGGGCTGGGCATGAAGGCACATGGTCACTGAAGGCAGCTGTCCTGCAGGCCGTAGGC CCTCCCAGGTGCTTGTTACTGGTAGATTTATGGAGGACCTAAATGCCAGACTAAGACATAGGCCCCGGCC ATATTTTGGGCTGTGTAGTTTTTTTGTTTTTAAGTTTTCAATGAGTTCTTAGTCAGAATGGCCTAATCTG TAGGAGAAAGCCCCATTCAAAAGAGCTTAAATAAGGGGATTGACTGTCTTAAAGTGCACAAAGTCCCAGG TTCCAGCTGCTGAAAAGCTGGTTCCTTTAGCTGAGCGTCAGTGGTAACCAGATTTCTTCATCTCTGCACT CCACTAGCTTTATGGTCATAGCAGGGCTGCAGCATCTCCTAAAGTGCTGGGGGCAGGCCAGGCACGGTGG CTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGACAGGCGGATCACTTGAGGTCAGGAGTTCAAGAC CAGCCTGGCCAACATGGCGAAACCCCATCTCTACTAAAAATACAAAAACTAGCTGGGCCTGGTGGCACCA GCCTATAATCCCAGTTGAGGCAAGAGAATCACTTGAACCTGTGGAGGAGGAGGTTGCAGCCTGGGCAACA GAGTGAGCAGAGCAAGACTCCATCTCAAAAAAAAAAGAGATTAGGGGGTAGACTTAAGGCTACTCAGACC TCAGGCTGGACGTTCTACCGCCTTAGCCATAGACAAGAGGCCGGTAGTTCCCATGACTGGCTGGGAGGAG GGCCCACCCTCCCTGAAGCATGTGGTAGGGGCCACTGAACAGAGTGAGGGTTCTATTAGCAAGGAACAGA TGGGGGCATGGCTGTTAGGAGGCAGCCTGCAGTGTGCATTGTAGTTGCCCCATTTAAAAATTGGAAATGA CATGTACAAATCTTCCAGCTTCTCTTGATAAATTGGAAGCTCAGGCAGCCTGGGTCCTACTTTTTTGGCT AGGCTGAGTAGGGAAAAGGGGGGCCCCCATTCCAATAGGGACCACTGAGCTGCCATCACCACCAGCATTT CCACCCAGATCTCTGAGTCCTCCTCTGACTGCAGTGCTTGCTCATCCTTCCAGCCCCCATCATCACACCT GCCCCAACAGGAGGGGATGGTAGCCAGTGGAACACTTCTAGGTGGCTCCTGCTTTTGGCTGGGGGTGTTA CAACCGGAGGTGAGCTGTGCTGGGACCACTGGCTTGTGCCTGCAACCTTGTCCCAGGCTGCTGTCACCTC TTGTCGAGACATTGGGCCAACAGCCCTGCAGCCCTCAGGTTTTAGCTGCATCGGAGTCATAAATCCCTTT CATGTTCGGAGTCAGCTCTGGAAGGAGCTAGCAGGGTGGAAGCATGTTTCCAGTGGCTGTGGGGCAGGTC AGGCCAGCAGGTATCCCTGTGCATGTGCAGGAAGGGGCCACGCTGCCTCCCCTGGAAACCAGAGTGCCTG AGGGTCATTGCCTACTGGCTGTTTCCCCCTCAGCAAATGCCCCACTCCCCGACCACGTGCTTATCCAGGT CTTGTCCCCTCAGAAGGACAGTAACTCCAAACCTGCCAGAAGCAAGACCCTGGCCCCAGCACCCCCAGAG AGGAACACGGAGGGGTCCTCGGAGAGCAGTGAGGAAGAGCTGCCACTGACCCAGGTGCGCCATGCCTTCT CTCTGCAGATGCTGCAGGATCAGAGCTGGGCTGGCAGGCCTTGCAGGAGAGGGCAGATCTTGCCCATAGG GAAAATCTCGCCATATTTAAACAGCACCTCACAGCTTCCAGAGCTCTTTCCTCTATTGTGACATTCATCT GAGCCCTGTGAGGCAGGCAGCAGTACACAGTTAAACATACAGGCTTCAGAGCCAGGTGGTGTTGGGGCGA AGCCCAGCTCTTCCACCCAACAGCCCCATGGTCCTGGGCAGATGCCTTTTCCCCTGTGTGAGGCTCAATG TTTCAGCCATAAAATGGGGACAGTACTGGCACCTCTCTCCTGCCTCTGTGCACTGGTGCCAGCACACAAG GTACTTGCCACAGTCCCCTGCCTAAGAAAGGGTGCCTGTTAACTGTGAGAAGGGCAGGGAGTGTTGCCCC ATTTGACAGATTGGGAATCAAGCCTTAGAGTTGAAGCAGTTTCCCCAAATTCTCATGATTCATAAGAGGC TGAGGAAAGGTCCAAACGCTGGTCCCCTGGCTCCCTGTATCTCTCTGTTTTCTGTTTAGGACCAGGAGTC TTCTTGAATCCCATGAGCTCTGCCCAGGACCCTCTCTCAAGCACCTGTGGCATACCTTCATGTGCTCCAC TGCACCCAGAGCTTAAGCCACAGTCCTGCTCAGGCTACACCTCCAAGGGTGGGACCAGGCCCACCTTATC TTCCTGTACTCCAGAGGCCCAAGTCAGCCATGCTGGTGTGGTCCAAGCTTCTGTGTGAACCCTGGCCCTT CCATCAGACAGCATTACCCTTTGTCCTCCTCTAGCCCCAAGCTCCCAGAAGCTTCTGCCAGGCACCTCAG AGCACCAGCTCCCCTGTCCCAGGGCCTAACCACAGATCCTGGAGTTCTGCAACCTCCAGACCAGAGCGGT CTCATGAACCACCTCCCCTTGAATATCACATACCACATTGTTATCAATTCATCAGTAAGGTCAGATGCTG TTTGCACACCTCCAGCAATAGGGTGCTCACTGCCTCTCACTTTCCAATGGCACAGATTACAAAAGTAAAG AACAACCACCACCAACATCGGTAACTCCCTGTATTCTCATTTTTCTGTTTAATCTCCACAACAGCCCTAT GAGGGTGGCTCCCTTTGTTGTTTGCATTTTAAGGAACTGGGAGTGAGGCTCAGAGAAGTTGAGGGACCTG TCCCAGCATCACATGGCTGATGACAAGTGGACAGACCTGGTGTTTGAGCACAGGCCATTCACATTCTGAC CCGTTGCCTGGTGCTGCCCCGACACTCTCCTCTCCTGGGCTTGGGCATTGCCCTCTGGCTCTGTGTGGAG CCTTTACGAGGCCACCTGCCTCTCTGAGGGATCTAAACAACTGGGAGGGAGGGGACCGCTCCCCCTTTCT CTGTGGGGGTGGACTAACACAATTAAAATGAACATCCTGCTTAAACTGAACCATTTAATTGGTATGTTAG TCCTGAAGATTCTGGAGTCTATTTAAAAAGCAGAAAAGAAGTCAGCGGTTTGTACATTCCCCCAGGAGGA TTCGGGGAAGACGGGCATAGCCCGGGGAAGCTGCAGCCTCTTCCTGATTGAGAGATTTTTAGTTCCTAAT CCCCAGCTCACTAATTATGATTATTTTCATTATTGTACATTTATTGAGCACCTCTCTATTGACAAGTTTC AGTCTGATTTTATTAGCCCATCAGTGGGGAAAGGGATTGAGGCCAGGGTGGTGGGCAGAGTCCCAGGCTG GGAGGCAGGGATAGATACCTTGGCTCCATTCCTAGACCCCTCACTGTGCCTCCGCCCTGTTGTGCAGAGT AGACCTCAGGCCAGAGTCTGTGCTGGGGTCAGGACAGCTTCCAGATTTAAAAACAAGTAGGTGATACATA TGTTAAATAACTTAATTTAGCTATTCCACAATGTATATGTGTATCAAAACATCATGTTATATACCACAAA TATATGCAGTTTCACTTGTCGGTAATATTTTTTAAGGCCAACTTCTTCTATTAGTTTGTCAAAGACGTAG GCCCTGCTCTCAAAGTTTTAGGTTGAATCAAAGAAAAAGGAAACCTGTAAGAAACTAAATTCTGGTGTTA CATTGAGGCCTAGCATAATTGGTTCTAGAAGGAGCTCCAGTCTGGTGCCTGGAGAACTAACTTCTAATCC TGGCTCTGGCACCAGTTTGCTGGTTGCCCTGGGTGAGGCCACTTGCCTTCTCTGAGCCTCATTCATCTCA ATCTCTGGGATGAGACTTCCTGGGTTGGTGGGGTGGACCTTGAGGCTCCAGGCCACATCCCCAGAGAGTA GAATTTCTCAGTCCCCTGGAGTGGGGCTGGCCTAGATCTGTTAAGCAGCCTCAGGCAATTCTGAGAGAGG TTCTTGGAGTGTTTGTTGCCTTTGTGGTCATGTCCCTTGCCAGGGTCCGCAGCCTAGGCCATCAGCCCCC TCTCCCCACTCTGTGACTTGCTGGAATGAAGGCACAGTTAGAATGAGCTCAGCTTTGACAGGATGGGGTG AGCACTGTCCAGAAAGCCCCTAGGTTTGGTTCTGCAGGCATCAGACCTACAGGTAGGAGGGGTATCCCAG GGTTCCCTCTGGGTCCTTACTGCCCAGCACCTATAGGGAGGTACAACCAAATGTTCAGGCCAGTGCTGGT TTTGCTGCTTCACTCCCATCAGTTTTTTTTCTAACTGACCCCAGAACTACATTCCTGTGTATACTGTGCT TTCCAGTTTCCACAGTGCATTGGAACCCCTCCAGTGAATGAGCCCAGGCTGGGATAACTACTAGCCGTTT CATTAAACGGGAAACTGAGGATCAGAAAGTTGAGGGGCTTGACCACACAGTGAAGTCATGAGAGAGGCGT AATGAGAAGCAGGTCTTCTCCTATACCCTGGGCAAGCTTCACTGCCCACCTTTATGAACTCTACAGGCTA ATGCCCCGCCCCAACCCCCCACAGCCAAGCCCCCTGCACCACCTCCCTCCTACGGCCCAGAGGCCCAGTG GGGTGGCGTGGGCAGGTGGAACTAACAGGAGGCTTTTGCTGCTGAGCTGCTTTTAACATCCCAAGACGCT ATTGTTTGCCTCAGTGGGTTCGTTGCTTCTCTTCGTCCCCGACAATCTGTTCCTGTCTTCACATATATAT AGATCCCCCCTCCCTCAACTGTAAGCCTTCTCCCACTTTCCATCCTTCTCTTTTTTATATCGTGGGAAGG AAGGCTCTGGAAGTGGCAGATCGGAGCAGCCGCGGGGGAGGCTATTTGGCAGGGGTAGGAAAGGCCTAAG CCCAGAGAAGCTTCCACCCTCAGGCAGGCACCTTTCTGTTTTACTTTTTACTTTATGCCTCTCCACAGCA CCTTAGCACCCTGAGGAGCCAGGTGTGCTAAGTCAGGCTCAGGGGGTAAACAGGATGGTGAAACAGAGAC CAGTCTGGACCTGATTCCACTCCTCTCTTAGCCTCAGGCAGCTCCCTCTTCCTGCCCTCCAGCTCTTCAC TGGCCAGAGAGGGAGCAGAGCTCAAACCAGATCTGACATTTGGGGAATGGAAAGTAGACCTGACCAGCTC CCTGGCTCACAACCATGTGTGTTCTCGTTAGCTGGAGGTTCAGGAAGGAAATGGGCCTGGAGATGCCCTC GTGTGCGGTGAACATGTTCAGGGATGGTGCAGTTCAAAACCAGACTGGCCTGCAGAATACCAGGGAGCTG CTGTTGCTTGTTTGCTTTTTCTTTTATTGTTTCCTTGGAAAATTTAAAGCATACCCAAAGATAGATAATG TAAAGAACCCCCACGTACCATCCCCAGCCTCAACAGTTAGGAACTCCTGAGCAGGCTCGTTTCACGCAAA CCCTCCACTCAGTTCCCCAACGCCCCTGGATTACTTTGCAGCCAGTCTCAGACATGTCAGCTCATCCACC AGGATTTCAGTATGCAGCTCTCAGTTATAAGGACCTTTTTAAGCACAACTACGATACAGTGTCACACCTA ATAAGTTGATCTACCCAGTCAGTGTCCCTATTTCCCTGATTGTCTCATGGAGTTCAGTTAAAGGCCACGT ACGGCATTGAGTTATTAATCCTCTAAGTCTTAATCTGTTGGTTCTCACCCACTCACCCAACCCTTGTTTC TCTTGTGCATTTTTTTGTTGAAGAAACTGAATTGGTATAGCTGGGGAGTTTCATCCTGGGCCATGTATCA GGAGGGCTGCATCAGAACCTCTGGGGTTGGGGCAACTAGACTGTAAATACCTCCCCAGGTGAATTGCATA TTCCAACCAGGCAGCCTTGGAAAACTGCTTAGACCACTCCCTGCATTCAGCAAGTAACTGTTTCTGAAGC CAGCCGGGGAAAGAAGGCAGAATTGGACATTCTGGCCGTGGCTTTGCTTCCAGTAGGGACAGCAGCCTTG GGTCGCTCCCTTTCCCTCTGGGCTTGTGGTTTTCCCACTTTGTATAAGGGAGCTGATCCTGCTGAATGTA GGGCTTCACTGTGAGGGTCAGGTGGGCTCTGGGAGTTGTGAAGTGCTGTGCTGGGTCTTAGCAGATGTGT GGGGTGGGAGGGGGCACCCTGGGCAGCTGGAATGGCTTCTGTGCCCAGCTGCCCCTGAGCTCAGTGGACC CTTTGCCTTGTAAAACACTCCCTAACCCCATCACCTCCTTTCCCTGGCCAAGCCTTTAATCACTGGGGGG GTGTTTTGTTTTTGTTTTTCAAGGTGATTAAACCCCCTCTGATTTTTGTCGACCCTAATCGTAGTCCAGC TGGCCCAGCTGCTACACCCGCACAAGCCCAGGCTGCAAGCACCCCGAGGAAGGCCCGAGCCTCGGAGAGC ACAGCCAGGAGCTCCTCCTCCGAGAGCGAGGATGAGGACGTGATCCCCGCTACACAGTGCTTGACTCCTG GTGAGCGCAGCCCTTATGCAGTGGTGGGAGGGGCTGCCAGCACTGCCCCACATTGAGGCCCAGAAGGGAC AGGACACTGGCTGAGTCACATAGCAAGGTGTTGGTCGGGAGGGGCTTGGGGTCAGGTCTCTGGGCCCTGC ATTAGCCATTCTGATTAGGGCCTGGCTCAGACCTGCAGTTCTGGGGGAATAGTTGCCAGAGCTTTTTTGT GGCAGCCCCAGTCATGGAGCCCAGACCAGTGGCTAGAAGCTGCAGGGACCAGGTTCCTACATAGTCTAAG AAAGAATTCTGTATCAGTTGACTGCCTGTGGAACAAGTGGTCAGGGTGGTAGTGAGCTTCCCGTCCTTGG TGGCATGTAAAGTAGGTTAGGCAATCCCTAAGCCAGAGACATCACAGGGATAGATTTCATCTATCAGAGA GACAGGACCAATCTGAGGTTTCTTTGACTTCTGAGAATCTGTGATTCTACCAATGACAACAGGAAAAGGG TTAATGTTACTATTACAGTTATTGTAACAGTTTTACAAGCAATAATACCTGATCCTGATAGGACAATTTA AAAATGCAGACGGGTGCAGTGGCTCACGCCTATAATCCTAGCTCTTTGGGAGGCTGAGGCAGGCAGATCA CCTGAGATCAGGAGTTCAAGACCAGCCTGGGTAACATGGCGAAACCCCGTCTCTACTAAAAATACAAAAA ATTAGCCTGGCGGGCGCCTGTAATCCCAGGTACTTGAGAGGGTAAGCCACGAGAATCGCTTGAACCCAGG AGGCAGAAGTTGCAGTGATCTGAGATGTGCCACAGCACTCCAGCCTGGGCGACAGTGAGACTGTCTCAAA AAAACAGAAAGCAGGCAAAATAGAGATTACTGCTGGGCATGGTGGTTCGCACCTGTAATCCCAGCACTTT AGAAGGCCAAGGTAGGAAGATCGCTTGAGCCCAGGAGTTCAAGACCAGCCTGGGCAACATAGTGAGAGCC CTATCTCTACCTATCTACCTACCTACATACATATGTACATATACATATACTTATACATATATGTGTGTAT GTGTGTGTATATTTTTTTAATAAAAATACAGATTAGCACATAAGAAACTATATCACCTGTAATTCTGCCC CAAATAATTACTGTTAACATTTGACAAATGCTAACTTTATAAAAACCTAAAATATACGTGTGTTTTTAAA GCAAGACCATACTGTATCTAATGTTCAGTAACCTTCACTGGATATTTTATGACATCGGGTTTTTTTCATC TTTACATATTTGCAGCACAATTCCTAATGGCTACAGAGAAATCCCTTGGGTGGACATGCTACAGTGTGTG TAGCCAGCACCATGTTGGAGGAAGCAGAGGGTTTTGTTTCAGGGTGGAGGGGTGAGGGAGTTGGCTGTTA TAAACAGTGCTTTGAAGAACATGCATGTAACCAGGCCTCTGCAGATAACCACGGGGACTCTTAGGAGAGA CGATTTTAACTGCAAGGAGAGTCGTTTGGTGCCGGTGCTCTGGCCCATTGCTCAGGAGTGGCAGCCCGAC CAGTTGGGAGGGGAGGGGATGAGGAAGCCTGGGGTCACCCCCAGAGCAGCCATTTGAGCTCCCTGAGCCT TGTCAAATGACATAATGACATCTCCTGCCTGGGAGGCTTGGAGAGGGAAGTAAACAAGCTTCTACCTCTG TAAGCCCTGAGCACAGCTCTAGATCACCAGCACAGGCCGGTAAATTGGGTTATTGCCGCTGCTGAGGAGG CGATGGGGCTTTTGTGCCCTGATGTGCCCCCATCTCGCTCCATTTCAGGCATCAGAACCAATGTGGTGAC CATGCCCACTGCCCACCCAAGAATAGCCCCCAAAGCCAGCATGGCTGGGGCCAGCAGCAGCAAGGAGTCC AGTCGGATATCAGATGGCAAGAAACAGGAGGGACCAGCCACTCAGGTACCTGGTGGGCAAGGGAGGGTAA TGCAGGCCAGTGGGGTGGGGCCCTACTTCCATACTTACCCACATGTGCTGATGGGATGGCCTGCAATTGC TGTCACGCCCACACTCCAGAGGTCGTGGCCTCACAGCCAGAGGCTTTCTGGCCTCCTAGCTACAACCCCC CAAATCACCTTTGAGTTATGAGGAAGAGTAATCTGGGGACACAGCCTCCTGGCCAAGCAAGCCCTGCAGC ACTCGAGTCCCTCATGAGATTTTCCAGCGTAGTGGGGCTTTTGATTTTTTTTCTTCCAGTTTTGAAATGC CATGAACAAAAGTTGCCCTTTTTTGGTGTTTGTAATAGTGACTTCAGCATTCTTCCAAGCCTTTACCATC TTCAGTGCATTTTTATTTGGTCCTTGCCTGAATCTAAAAGCTGGGCATTTTAGGGTTAATGGCTGGTGCA TTGTTTAGATCATAAAACTTAGCACACATCCCCACCCCAAGGGCTGCGATGTGACCAGCATTCAGCAAGG CCGGAACCCGGGTCTTCTGAGACCCAGTTCATTGCTCTTTGGGCCATATCAGTCTGGTTTCCCATCCCAC TGAGAGGATGAAGTCCATGACACACTCTGACCTCTCTTCCTGAGGGGTGGGCTAAGGGGGTGTTGGGGGG CGGTGGGGCTGGTGTGCCACCCACTCCCTGGGCTCATCACAAGCTCCAGGTCAAAAACTTCTGGGAACAT GGGTGTCGGATGGGAAGTCAGGCTGTGGTCACTGCATCCATGAGCATCGGTTCCTGCCAGGCCCTAGGGA TACTGCAGGAACCAAGACAGGGACAAGGAATTCCCAGGCCAGTCAGGGAGTGGTGAGGGGCAGCGATTAA ACAAGGAAACCCACATATAAATAAAAAGTATTCACCAGCTGGTAGGAGAGGAAACAATAAAAACTAGAGA ATAGTGGGGTGACCTGCTATATGAAGGCCTCCTGAGACAGCGATGCTTAAGCAGAAAAAGCAGCCAGTCA CAGGATGAGCTGGGCCACCCTCCAGGCAGGGAAACTGCAGGTACCAGGTCTTCGGGGGAAGCGCTTGGGA ATGAGGGAAACTGAGAGGTGGGGACAGCTGGATGAGGAGCTGGGGGAGAGGAGATGAGCCAGGCCGTGGC AAGAGCCACGCCACATTTGAAGGCTCTCAGCAAGGGGTCATGCCCAATTTCCATGCCCACCACTCTCCCT GACTGCTAGTGGTTATAAGAAGTAGAGATGGGGGTCCACCAGGTTGGAGATTATCCCCAGTGAAGGTGCA GATTGAGTAGTGGGGCCTAAGCTGCTTCCCTGCCCTGGGCTGGGAACTGTCCCTTGCTCCTTGAGAACAA TGTGATTCGCTCATAACCTGAAGCCTGCCACCAGTTTTGCCCCTTTGACTGCCCCTCAGTCCCTGCTCCA GCCCTCACCCCAGCCAGACAGCATCTGACCAGGGTGTGGCACAGCTGGCATCCCAAGGACTTGTGAGTCT GAGGGCTACCTCTTGCCACCCACAGGTGTCAAAGAAGAACCCAGCTTCCCTCCCACTGACCCAGGCTGCC CTGAAGGTCCTCGCCCAGAAAGCCAGTGAGGCTCAGCCTCCTGTTGCCAGGACCCAGCCTTCAAGTGGGG TGAGCTTGGGGAGCCAGGGGAAGCAAGCCCACGGAGCGTAGAAGGTGCAGGCGTGGCCCTGCATCGCGGC ACCAGCACTCATCTGCCCCATGACCTCTGCACTTGGTTTGCCTCCCTCGGCCTCAGTGGCCTAATCTGTA AGAAGGAATTACAGTACCTTTCGTAGTTGGAAGGATCAAATGAGGCTGCATGTGTGCCCCATCTAACACA GTTCCTGGCCCTACTGAAGTGTTCAGGAAGGACCAGGTCTTACTTGCCCTAATTTTTCCTTCCATTCCTT CTCCTTTCACCGAATTAGGTTGACAGTGCTGTGGGAACACTCCCTGCAACAAGTCCCCAGAGCACCTCCG TCCAGGCCAAAGGGACCAACAAGCTCAGAAAACCTAAGCTTCCTGAGGTCCAGCAGGCCACCAAAGCCCC TGAGAGCTCAGATGACAGTGAGGACAGCAGCGACAGTTCTTCAGGGAGTGAGGAAGATGGTGAAGGGCCC CAGGGGGCCAAGTCAGCCCACACGCTGGGTGAGGGTGCCAGGGGAAAGGCAAGGGTGGGCCAGGAAGAGG GTGTTGTGTGGCCTGGTGGAGCCATAGCTCTGGCCTCAGCTCCATATCTCAGACTCATTCTGCACCTGTG GCTGAGCCTGGGCCTCAGTTTCCCCACCTGTACAACTTCATGAGGAAGTCAATCCAAATGATTTCAGAGA CCTGACTTTGCTGTTTGACCACTCTCAGCTTTTTGGTATCAGACTCCCTTCACTGGCTCCCAAAAACTCC AGGGCCATGTTTCTGGAACAGTGGAAAGCAGGGAAATAGAAATGGGGCCTCAGGAATTAGAAATAAGGCT TTGGCATTCAAATGTCGCACCTAGCATGCTGTGACTAGCGATAAGTGTGCAAGGAGTGTTGAAGCAGTAG GAAGACTTGTGGTGAGGCGGGGCAGGGGATGGGGGTGAGGGACCTGCAGAGAGACCAGGGCCTTCCTGAA GGGCTCTGCCCTTCCCGGCTGGCAGGGGCCACCTGGGGCTACCAACAGGATACTGTGCTTCTCCAGTAGG TCCCACCCCCTCCAGGACAGAGACCCTGGTGGAGGAGACCGCAGCAGAGTCCAGCGAGGATGATGTGGTG GCGCCATCCCAGGTAACTGCAAGGGAGAGGACTGGCAGCCCATAGGCCTTAGGGTGGAGCCCCAGGCCAG GCTCCTGTCTACCCGATCCCTCAGGTCAGGGGTCTGGGTCCCCTCTCTTCACAGAGGCCTTGGGCAAGGT CCTGTCTGCAAGGCACCACGTGTGGCCCAGCCAGCAGACCACAGCCAGGCTGCCTCCGTCCCCTCATAGA GCCCTGAGTAGCTGACCCTTGGGGTCTGTAGAAGGGATTGACCTTGATTCTGGGTGATGTCCGGACAAAA ACATTCTTTAGCAGATTTATTTTAAGGTTACTATCTGTATGTGGCAAAAGCTAGTAATTTTCCATTTGTA TTAATAAGAAATTTCCTTTTTAAATGTGCCTGTCTAGAAAGTGTATTAATTAAAATAGTTCAGGAGGCAC ACGCCAAGGGCTGAAGTGCTGCTCTGTGCCTTGTTGTCCACCCACTCTGCACTGATAGGGCAGGGTGATC CTAGAGGCCCCAGGCTGCTTTCCTCACAGCAGGCCATGACTCGGGCTGGGTTATGGCAGTGGGGTGGGGT GGTGGCAGCCTCTTTCACAATGGGCTTCTTCAGTCTCTCCTCTCAGGTTATATGACCCCTGGACTAACCC CAGCCAATTCCCAGGCCTCAAAAGCCACTCCCAAGCTAGACTCCAGCCCCTCAGTTTCCTCTACTCTGGC CGCCAAAGATGACCCAGATGGCAAGCAGGAGGCAAAGCCCCAACAGGCAGCAGGCATGTTGTCCCCTAAA ACAGGTAAGTTAAGGTCTGCAGGAGGGACATAGCAGGACACAGAGGGACAGGGCAGTGGGCCCCTTCTTG CCCTCCTGTAGCAACAGTCCTCCCAACATGGTCCTGTCTGCCCCCAGAGCCTCTCCAAGTGAGACCTTGT GGCCTTGCATTGGACCTGAAGATGCTCATCAAAGTGCAGGTGGGGCCAGGTGCAGTGGCTCATGCCCATA ATCCCAGCACTTTGGGAGGCCGAGGTGGGCAGATTGCTCAAGCCCAGGAGTTCAAGGCCAGCCTGGGCAA CACAGAGAGACCCCATCTCTAAAATTTATTTTAATTAGCCGGTGTGATGGTGCACGCTTGTAGTCCCAAT TACTTGAGAGGCCAAGGCAGAAGAATGACTTGAAGCCAGGAGGTTGAGGCTATAGTGAGCCATGATCATG CCACTACACTCCAGCCAGGGTGGTACAGTGAGACCCTGTCTCAAAAAAAAAGTACAGGTGGGCCCCACGC CCAGGTGTCTGGCTCCCATGGCCCTGGACAGCCTGGAAGTGGGGGTGTATCCAGCCCTGGGTGGTGCTGA TGCACCTGGTAGGATAGCCCTTGCCTCAGAGGAAGCTGCGTCTTTTGGCTTGTGGAGCAAGTGTTGGCTC TCTCCAACCATCACCATCAACTTTTCTTCCCTGTAAATAGGCTCACGGTGTGGGCCTTGGGCCTCAGAGG ATAGCTTAGACAATAGGCTGACAGTCACGTTTGGAGGACACTCAGCACATGCAGGAGACCCCAGGCAGTA GACTGGCCCCAGGCTGTTCTGACTCATTGTAAAGCCTTGGAAATCCCCTGGCCACTCTGGACCTCTGTGT CTTAACCATACAAAACAGCAGTTGATGTATCCAGTCTGTGTCAAGGCATGGCACATGTAGAAAATAGTCA CATTGTATTTGGAGGGCAGACTGGATTATTCAATTCACCTAACCTGGGGCATCCACACTCCCTGACCCTA CTGGAGCTAAGGGTCAAATATGTACCAGCTGGGCACACTTGGGACAGCTCCAGGGCTTCCCCAGCCTTGG TGTTCTGGGTGTTTGCAGATAAGCAGCAGAAAAGTGGGCCTGGCGCAGTGGCTCGTGCCTATAATCCCAG CACTTTGGGAGGCCAGGGCGAGTGGCTCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTG AAACCTTGTCTCTACTAAAAATACAAAAAACTAGCCAGCATGATGGCAGGCGCCTGTACTCCCAGCAACT CAGGAGGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGTAGAGGTTGCAGTGAGCCGAGATTGCACCAC CGCACTCCAGCCTGGGCAACAGAGCAAAACTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAGGCAGCAG CAGAAACGTAGGCTCTGGGGAGAGAGGTTTCCGGGGCTAACTGCCCTCCCCAGCTTCCCTCTCCATTGGC TCCTGCCATCTTGAAGAATCCCCAGAGGATGGAATTGGGCCTCCAGCCGTCCCGGGGGCCCCTCTGCCTA ACCTGGCCTGCCCTGCCCAGTCCACCTCCCCCAGCCCACCGCAGCTCTAGAGCCAAAAGTCGCCAGAAAT CCTGGTTGGGGCTGAGGGGCCAAGCTCACTGCATGCTGCAGGGGGCAGCCCTAGCCTCAGTGTGACATGA GTACCACATAGAGTGTGACATGGAGTATCCACCTGGGCCTTCCTCCAGGCAAACACCTCCAGGACCAAAC CACCAAGCCACCTTTCAGAGCCCAGCATGCAGGAGTGTTGTGCCCATGAGACCCAGAATGGGGCAGAGAC CTCCAAGTCACTTGGAAGTTAGAGCCGGTGAGGAGACCCAGTCATGGGGCTTTCAGCTGCAGCTTGCCCC AGGCTGGGTCGGAAGAGGAATTGCTGCTCACTTTCTTCCCCAACATTCTCTGTGAGAGGCGGTGCGACAA GGAGACATTTTAGAGGGGGCTGTGGAAGGTTTTTTTTTTTTTACACGTGTAGTCAGCACACAATTATCAA AGGCAAGCAGAGGCGTGGAAAATTCTAAACAAAGGCTGCACCAGAAGTCTCTCTGGCAGGCAGTAAACCT GCTTAGTCAGCCACCACGTGTATATACACTGCACCCAGAGCTCCCCACCTTGCCTGGACCCCCTGACCAG GAAGGGCCGAGTGTGGGTAATCATCAGTTGAATGTCTGCATGGCCCCCACTTTTATTATAAATCTACAAT GTATCATAGGAAGCCTTACTGTTCATCCACCCCTCACGTTATAGACAGGGAAACCAAGGCCCTGGGAGGA GATGGGTCCTGGCCAGAATCACACTGAAAGTGGGTGGGAAAGTCAGACCTAGAACCCAGGTCTCCTTCCT CCCAGCTCCAGACTCCATCTCCCTCCTTTCTGAATTTTCATTCCATTGATAGATTTCAGGCCCTTTCATT AACATTCTGGAGTCATTTTCTGTCCCCCACCCTAACTGGAGTTTTTAGTATAAAGAGACAGGGAAAAGCT GTAAGTTAGAAATGAAGTCAGGGTGTGAAATTGGTGGAAAGGTGTGAGCTTAGGAGACCAGCTGGGGCAG AGTGACCGCCAAGCCTTGCTCTCCCCATCTGTGCCATTGTAAGAAAAGATGGAGTCACTCCCTGCACCCT CTTCGCTCTTAGGTACCATAAGATCTGTCCCCCAACTCTCCCAGATCTGTGACCCCACATTCTCTCTCCA TAGGTGGAAAAGAGGCTGCTTCAGGCACCACACCTCAGAAGTCCCGGAAGCCCAAGAAAGGGGCTGGGAA CCCCCAAGCCTCAACCCTGGCGCTGCAAAGCAACATCACCCAGTGCCTCCTGGGCCAACCCTGGCCCCTG AATGAGGCCCAGGTGCAGGCCTCAGTGGTGAAGGTCCTGACTGAGCTGCTGGAACAGGAAAGAAAGAAGG TGGTGGACACCACCAAGGAGAGCAGCAGGAAGGGCTGGGAGAGCCGCAAGCGGAAGCTATCGGGAGACCA GCCAGCTGCCAGGACCCCCAGGAGCAAGAAGAAGAAGAAGCTGGGGGCCGGGGAAGGTGGGGAGGCCTCT GTTTCCCCAGAAAAGACCTCCACGACTTCCAAGGGGAAAGCAAAGAGAGACAAAGCAAGTGGTGATGTCA AGGAGAAGAAAGGGAAGGGGTCTCTTGGCTCCCAAGGGGCCAAGGACGAGCCAGAAGAGGAGCTTCAGAA GGGGATGGGGACGGTTGAAGGTGGAGATCAAAGCAACCCAAAGAGCAAGAAGGAGAAGAAGAAATCCGAC AAGAGTGAGTGACCGCTTCTCCCAGCCCACCCCAAGGGCTGCTGGGCACCCCACGGGGGCGGGAGGGACC CTCAGCCAGCACCTGGTCTCATTCCTCCCATGTAGAAAAGAGAGGCTGAGACCAGCCTGGCCAACATGGC AAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCTGGATGTGGTGGCGGGCACCTGTAATCTCAGCTA CATGGGAGGCTGAGGCAGGAGAATTGTTTGAACCCGGGAGGCAGAGCTTGCAGTGAGCCGAGATCACGCA TTGCACTCCAGCCTGGGTGACAGAGCAAGACTGTCAAAAAAAAAAAAAAAAAAAAAGGCTGAGAAGTGGT TTGTCCAGAGTCACAGGGGCAGCTTGTGGCAAAGCCCGAACTCGATTCCAGAGCACTTGAGTCAGCACTG CCAGGAATGCTCCAGAAGGACGAGGAGTCATGTCCTCTTTCCCCAAGCCCAGTGCAGCAGATCTTGGAGG AACCTGCTTCTCCAGCCAGCTCCTGGGTGCAGAATGGACCAGGAACCAGACTGTCAGAATCCTCATCCCA AACCCCATCTTGTCTCTAGACCTCAGTTTTCCCTCCATAGTAACACTGGCCCTTTACTGAGTGCTGTTCT AGACTCCGCATGCAGCAGGACCTCATTTAGGTAGAAATGAGACTCAGCAGGTAGAAAACTGCGGCTCGGG CTCGGAGAAGTAGAGATGCTGTTCAGGGCCACAGAGTTTTGCTAGGTGGAGCCAGAGTCAAACCTAGGCA GCACTCTCGAGCATCGCCCTGGACGGTGGGTTGCCAGTGACGCCCGAAGAGCCAGCTCGTTCTGGAACAA AAGTCGGGCACCCTCAGAGCAGGACTTGCAGCCCCTTGGTGCTCAGAACTGTGCTAGATTTCCATTTACA GTAGGGATAGATAGTGTCCATTTAAAATAAATTTGCGGGAGTTTTAAAAAGTGAGTTGAGCTAAAGAAAA ATGGTAGTCATCCAGGTGGTCCATGGATGGGACAGAAATCATGAGCTGGCCTCCAGGGGGCAGGTGAACT GGCCCTGCTGGGTGATCACCACAGCTGCCAGCCTGTTTTATTTTTATTTTTTGAGACAGGGTCTTGCTCT GTCACCCAGGCTGGAGTTCAGTGTCAGGAACGCAGCTCACTGCAGGCTCAGCCTCCCAAGCTCAAGCGAT CCTCTTGCTTCAGCCCCCCAAATAGCTGGGACCACAGGCGTGCACCACCATCCCCAGCTAATTTTTGTAT TTTTTGTAGAGACAGGTCTCACTATGTTGCCCAAGCTGGTCTTGAACTCCTGGGCTTAAGCAATCCACCC GCCTCAGCCTCCCAAAGTGCTGGGATTGCAGGAATGAACCTCCACGCCCCGCCCTGCTGGCCTGTTGTGA TGGCTTCTGGTGGTGTGGGGAAAGCTGGGAGCCCTGCCCTGTGCACCTCCCAACATTGACCCCAGCACTT AGGATTACCATCTGTTGTTCAGGAACTTTACTTTACTTCCCTTAGGAAAAAAAGACAAAGAAAAAAAAGA AAAGAAGAAGAAAGCAAAAAAGGCCTCAACCAAAGATTCTGAGTCACCGTCCCAGAAGAAAAAGAAGAAA AAGGTAGAGAGTTCCTGGGGTGTCTCAGGCCAGAAAACAGACCCAAACCCAAGCCCCCTCCTACACACCC AGACCTGGTTCCTGCCCCCTTCCCATTTTCGGGGCCCAGTCGGGGGCGTCAGGGGTTGTGACACACCAGG GAAGAGGCTGGCAGGGCATGTTCCCTGAGCACATGGAAGCCGTAGAAGTGGCCTGCCGGAGGTAGAAGGG TGTTGGGGAAGGAAGGAGAGACTCCCCCCAGCACAGGGAAACCAGGTAGACTGTGGCAGGTTTCCAGGTG AAAGGAAACGTTGCCTGGGCTGCGTGTGCCCCAGCTGGCAGGCTAGCCCTGAACAACAGCTGTCCTCACG GCGCGGGGCCTTAGCACCTCAGACACAGATGAAGTTCTCACCTTGGCCAGCAGGGCCTCAGCTGTATTTA GGAGAGCTGAACATCTGTTTGCCTCTGCCCTTGGAGGTCGCTGCAGACCCAGTATCTATTCTAGGGGAAT TCACTAGTCCTCAGGAGGTGGGGGCAGCAGTGGGTGGGGAAAAGCTGCAGGTCTGAGAGCCTCTCGTACT TCCCTCCTCACAGAAGAAGACAGCAGAGCAGACTGTATGACGAGCACCAGCACCAGGCACAGGTACGCTT CCCAATCATTCCTGAGCATTCAGGGTGGGAGGACAGCTCTGGTGTCCCCTGTGGTCCCAGAGAGCCAGGC AGACCTGATAGGTGGGCTCTAAGGGGAAAGGAGGCTGGGGAAAGAGGTTCTGTTGCCAAGGGTCCATGGG GCCACTGGGGTGACATCAGGAGCTGGCACTGCAGCATCAGAAGGATCCAGAACAGTAATGGCAGTGGTGA CACCGAGTGCACCTGGGTGCAGGGGTTGTGCATGCTTTAGGGGGTGTGCCCTGGGATGGAGCCTGTTTGT AGGTGAGGTCGGATACAGCTTGGTTCCTCCTTCACTTGTGAGCGGTTCATTTTCCTCATGATCCTGTAAC TTGGGGGCATTTCCTTTTGGGAAGGAAGATGGTTTACTCAAGATGAGCTATCACCATGGATCTATGCTTC CCTATGGAGGACAGGCCCTGCCAAGTGGTGGTGACAGTTAGCTGCTCCACCTGGCTCTGCTGGCCCTGTG GTCACCCAGCCTCCTGTAAATGGGGGTGATGCAGAGCCCGCCTCCTGGGCCAGTGGTGAGGCTTATGTGA AGCTAAACTAAACACTAAAGGACTCAGCCCAGTTCTCAGAACATTCCAAGTGCTAAAAAATGTCCACTGT GGTTAATGCCTCCCCCCTGCATTGGAGATGCCAGATTTCATTTTCCTTGCAGGGGAAAAGGGTCAGGAAA TTTGACATCTGCATGTGTTTCCTTCCCCTAGGGATTTCCTAGCCGAGCAGTGGCCATCCCCATGCCTCTG ACCTCCACCGACCTCTGCCCACCATGGGTTGGAACTAAACTGTTACCTTCCCTCGCTCCACAGAAGAAGA CAGCCAGCTTCAGGGGTCCCTGTGCTGGCCAAGCCAGTGAGCCTGCGGGGAGGCTGGTCCAAGGAGAAAG TGGACCAGCTCCCATGACCTCACCCCACTCCCCCAACACAGGACGCTTCATATAGATGTGTACAGTATAT GTATTTTTTTAAGTGACCTCCTCTCCTTCCACAGACCCCACATGCCCAAAGGCCTCGGGACTTCCCACCA CCTTGCTCCACAGATCCAGCTAGGCCTGACCTGTGCCTCATCCCGTGCCGCTCGGTCTCTGGCTGATCCC GAGGCTTTGTCTTCCTCTCGTCAGTTCTTTTGGTTGTGTTTTTTGTTTTTTTTTTAATAACTCAAAAAAA AAATAAAAGACTTGGAGGAAGGGTGCAAGCTCCCAGTGCA Download Select all
Length	42670
OMIM ID	606847
HGNC ID	HGNC:11654
Unigene ID	Hs.519672
Ensembl ID	ENSG00000070814
PharmGKB ID	-

mRNA Information

mRNA ID	NM_001135243.1
Exon	join(1..216,3518..3573,6475..6614,10206..10279, 11078..11264,11891..11964,14368..14598,16536..16748, 16979..17173,17316..17525,17701..17916,18083..18271, 18444..18692,18785..18982,21267..21404,21591..21770, 21894..22094,30264..30450,32249..32385,33906..34019, 34319..34538,35070..35152,35734..35914,38644..39204, 40716..40813,41384..41432,42172..42670)
mRNA Sequence	>6949 GAAAGAGGAGCCGGAAGTGTGGCGCGCGAGGTCTAAGGGCGCGAGGGAAGTGGCGGGCGGGGAC TAAGGCGGGGCGTGCAGGTAGCCGGCCGGCCGGGGGTCGCGGGTATGGCCGAGGCCAGGAAGCG GCGGGAGCTACTTCCCCTGATCTACCACCATCTGCTGCGGGCTGGCTATGTGCGTGCGGCGCGG GAAGTGAAGGAGCAGAGCGGCCAGAAGTGTTTCCTGGCTCAGCCCGTAACCCTTCTGGACATCT ATACACACTGGCAACAAACCTCAGAGCTTGGTCGGAAGCGGAAGGCAGAGGAAGATGCGGCACT GCAAGCTAAGAAAACCCGTGTGTCAGACCCCATCAGCACCTCGGAGAGCTCGGAAGAGGAGGAA GAAGCAGAAGCCGAAACCGCCAAAGCCACCCCAAGACTAGCATCTACCAACTCCTCAGTCCTGG GGGCGGACTTGCCATCAAGCATGAAAGAAAAAGCCAAGGCAGAGACAGAGAAAGCTGGCAAGAC TGGGAATTCCATGCCACACCCTGCCACTGGGAAGACGGTGGCCAACCTTCTTTCTGGGAAGTCT CCCAGGAAGTCAGCAGAGCCCTCAGCAAATACTACGTTGGTCTCAGAAACTGAGGAGGAGGGCA GCGTCCCGGCCTTTGGAGCTGCTGCCAAGCCTGGGATGGTGTCAGCGGGCCAGGCCGACAGCTC CAGCGAGGACACCTCCAGCTCCAGTGATGAGACAGACGTGGAGGGGAAACCCTCAGTAAAACCA GCCCAGGTCAAAGCCTCATCAGTTTCTACTAAGGAGTCTCCAGCAAGAAAGGCGGCCCCAGCCC CTGGGAAGGTGGGGGATGTGACACCCCAGGTCAAAGGAGGGGCCCTGCCCCCAGCCAAGAGGGC CAAGAAGCCAGAAGAGGAGTCAGAGAGTAGTGAGGAGGGATCTGAAAGTGAGGAGGAGGCCCCT GCAGGGACACGAAGCCAGGTAAAGGCCTCTGAAAAAATTCTCCAGGTCAGAGCTGCCTCAGCCC CTGCCAAGGGGACCCCTGGGAAAGGGGCTACCCCAGCACCCCCTGGGAAGGCAGGGGCTGTAGC CTCCCAGACCAAGGCAGGGAAGCCAGAGGAGGACTCAGAGAGCAGCAGCGAGGAGTCATCTGAC AGTGAGGAGGAGACGCCAGCTGCCAAGGCCCTGCTTCAGGCGAAGGCCTCAGGAAAAACCTCTC AGGTCGGAGCTGCCTCAGCCCCTGCCAAGGAGTCCCCCAGGAAAGGAGCTGCCCCAGCGCCCCC TGGGAAGACAGGGCCTGCAGTTGCCAAGGCCCAGGCGGGGAAGCGGGAGGAGGACTCGCAGAGC AGCAGCGAGGAATCGGACAGTGAGGAGGAGGCGCCTGCTCAGGCGAAGCCTTCAGGGAAGGCCC CCCAGGTCAGAGCCGCCTCGGCCCCTGCCAAGGAGTCCCCCAGGAAAGGGGCTGCCCCAGCACC TCCTAGGAAAACAGGGCCTGCAGCCGCCCAGGTCCAGGTGGGGAAGCAGGAGGAGGACTCAAGA AGCAGCAGCGAGGAGTCAGACAGTGACAGAGAGGCACTGGCAGCCATGAATGCAGCTCAGGTGA AGCCCTTGGGGAAAAGCCCCCAGGTGAAACCTGCCTCTACCATGGGCATGGGGCCCTTGGGGAA AGGCGCCGGCCCAGTGCCACCCGGGAAGGTGGGGCCTGCAACCCCCTCAGCCCAGGTGGGGAAG TGGGAGGAGGACTCAGAGAGCAGTAGTGAGGAGTCATCAGACAGCAGTGATGGAGAGGTGCCCA CAGCTGTGGCCCCGGCTCAGGAAAAGTCCTTGGGGAACATCCTCCAGGCCAAACCCACCTCCAG TCCTGCCAAGGGGCCCCCTCAGAAGGCAGGGCCTGTAGCCGTCCAGGTCAAGGCTGAAAAGCCC ATGGACAACTCGGAGAGCAGCGAGGAGTCATCGGACAGTGCGGACAGTGAGGAGGCACCAGCAG CCATGACTGCAGCTCAGGCAAAACCAGCTCTGAAAATTCCTCAGACCAAGGCCTGCCCAAAGAA AACCAATACCACTGCATCTGCCAAGGTCGCCCCTGTGCGAGTGGGCACCCAAGCCCCCCGGAAA GCAGGAACTGCGACTTCTCCAGCAGGCTCATCCCCAGCTGTGGCTGGGGGCACCCAGAGACCAG CAGAGGATTCTTCAAGCAGTGAGGAATCAGATAGTGAGGAAGAGAAGACAGGTCTTGCAGTAAC CGTGGGACAGGCAAAGTCTGTGGGGAAAGGCCTCCAGGTGAAAGCAGCCTCAGTGCCTGTCAAG GGGTCCTTGGGGCAAGGGACTGCTCCAGTACTCCCTGGGAAGACGGGGCCTACAGTCACCCAGG TGAAAGCTGAAAAGCAGGAAGACTCTGAGAGCAGTGAGGAGGAATCAGACAGTGAGGAAGCAGC TGCATCTCCAGCACAGGTGAAAACCTCAGTAAAGAAAACCCAGGCCAAAGCCAACCCAGCTGCC GCCAGAGCACCTTCAGCAAAAGGGACAATTTCAGCCCCTGGAAAAGTTGTCACTGCAGCTGCTC AAGCCAAGCAGAGGTCTCCATCCAAGGTGAAGCCACCAGTGAGAAACCCCCAGAACAGTACCGT CTTGGCGAGGGGCCCAGCATCTGTGCCATCTGTGGGGAAGGCCGTGGCTACAGCAGCTCAGGCC CAGACAGGGCCAGAGGAGGACTCAGGGAGCAGTGAGGAGGAGTCAGACAGTGAGGAGGAGGCGG AGACGCTGGCTCAGGTGAAGCCTTCAGGGAAGACCCACCAGATCAGAGCTGCCTTGGCTCCTGC CAAGGAGTCCCCCAGGAAAGGGGCTGCCCCAACACCTCCTGGGAAGACAGGGCCTTCGGCTGCC CAGGCAGGGAAGCAGGATGACTCAGGGAGCAGCAGCGAGGAATCAGACAGTGATGGGGAGGCAC CGGCAGCTGTGACCTCTGCCCAGGTGATTAAACCCCCTCTGATTTTTGTCGACCCTAATCGTAG TCCAGCTGGCCCAGCTGCTACACCCGCACAAGCCCAGGCTGCAAGCACCCCGAGGAAGGCCCGA GCCTCGGAGAGCACAGCCAGGAGCTCCTCCTCCGAGAGCGAGGATGAGGACGTGATCCCCGCTA CACAGTGCTTGACTCCTGGCATCAGAACCAATGTGGTGACCATGCCCACTGCCCACCCAAGAAT AGCCCCCAAAGCCAGCATGGCTGGGGCCAGCAGCAGCAAGGAGTCCAGTCGGATATCAGATGGC AAGAAACAGGAGGGACCAGCCACTCAGGTGTCAAAGAAGAACCCAGCTTCCCTCCCACTGACCC AGGCTGCCCTGAAGGTCCTCGCCCAGAAAGCCAGTGAGGCTCAGCCTCCTGTTGCCAGGACCCA GCCTTCAAGTGGGGTTGACAGTGCTGTGGGAACACTCCCTGCAACAAGTCCCCAGAGCACCTCC GTCCAGGCCAAAGGGACCAACAAGCTCAGAAAACCTAAGCTTCCTGAGGTCCAGCAGGCCACCA AAGCCCCTGAGAGCTCAGATGACAGTGAGGACAGCAGCGACAGTTCTTCAGGGAGTGAGGAAGA TGGTGAAGGGCCCCAGGGGGCCAAGTCAGCCCACACGCTGGGTCCCACCCCCTCCAGGACAGAG ACCCTGGTGGAGGAGACCGCAGCAGAGTCCAGCGAGGATGATGTGGTGGCGCCATCCCAGTCTC TCCTCTCAGGTTATATGACCCCTGGACTAACCCCAGCCAATTCCCAGGCCTCAAAAGCCACTCC CAAGCTAGACTCCAGCCCCTCAGTTTCCTCTACTCTGGCCGCCAAAGATGACCCAGATGGCAAG CAGGAGGCAAAGCCCCAACAGGCAGCAGGCATGTTGTCCCCTAAAACAGGTGGAAAAGAGGCTG CTTCAGGCACCACACCTCAGAAGTCCCGGAAGCCCAAGAAAGGGGCTGGGAACCCCCAAGCCTC AACCCTGGCGCTGCAAAGCAACATCACCCAGTGCCTCCTGGGCCAACCCTGGCCCCTGAATGAG GCCCAGGTGCAGGCCTCAGTGGTGAAGGTCCTGACTGAGCTGCTGGAACAGGAAAGAAAGAAGG TGGTGGACACCACCAAGGAGAGCAGCAGGAAGGGCTGGGAGAGCCGCAAGCGGAAGCTATCGGG AGACCAGCCAGCTGCCAGGACCCCCAGGAGCAAGAAGAAGAAGAAGCTGGGGGCCGGGGAAGGT GGGGAGGCCTCTGTTTCCCCAGAAAAGACCTCCACGACTTCCAAGGGGAAAGCAAAGAGAGACA AAGCAAGTGGTGATGTCAAGGAGAAGAAAGGGAAGGGGTCTCTTGGCTCCCAAGGGGCCAAGGA CGAGCCAGAAGAGGAGCTTCAGAAGGGGATGGGGACGGTTGAAGGTGGAGATCAAAGCAACCCA AAGAGCAAGAAGGAGAAGAAGAAATCCGACAAGAGAAAAAAAGACAAAGAAAAAAAAGAAAAGA AGAAGAAAGCAAAAAAGGCCTCAACCAAAGATTCTGAGTCACCGTCCCAGAAGAAAAAGAAGAA AAAGAAGAAGACAGCAGAGCAGACTGTATGACGAGCACCAGCACCAGGCACAGGGATTTCCTAG CCGAGCAGTGGCCATCCCCATGCCTCTGACCTCCACCGACCTCTGCCCACCATGGGTTGGAACT AAACTGTTACCTTCCCTCGCTCCACAGAAGAAGACAGCCAGCTTCAGGGGTCCCTGTGCTGGCC AAGCCAGTGAGCCTGCGGGGAGGCTGGTCCAAGGAGAAAGTGGACCAGCTCCCATGACCTCACC CCACTCCCCCAACACAGGACGCTTCATATAGATGTGTACAGTATATGTATTTTTTTAAGTGACC TCCTCTCCTTCCACAGACCCCACATGCCCAAAGGCCTCGGGACTTCCCACCACCTTGCTCCACA GATCCAGCTAGGCCTGACCTGTGCCTCATCCCGTGCCGCTCGGTCTCTGGCTGATCCCGAGGCT TTGTCTTCCTCTCGTCAGTTCTTTTGGTTGTGTTTTTTGTTTTTTTTTTAATAACTCAAAAAAA AAATAAAAGACTTGGAGGAAGGGTGCAAGCTCCCAGTGCAAAAAAAAAAAAAAAAAA Download Select all
Length	5113

CDS Information

Location	join(109..216,3518..3573,6475..6614,10206..10279, 11078..11264,11891..11964,14368..14598,16536..16748, 16979..17173,17316..17525,17701..17916,18083..18271, 18444..18692,18785..18982,21267..21404,21591..21770, 21894..22094,25424..25534,30264..30450,32249..32385, 33906..34019,34319..34538,35067..35152,35734..35914, 38644..39204,40716..40813,41384..41410)
CDS Sequence	>lcl\|NM_001135243.1_cds_NP_001128715.1_1 [gene=TCOF1] [protein=treacle protein isoform d] [protein_id=NP_001128715.1] [location=109..4575] ATGGCCGAGGCCAGGAAGCGGCGGGAGCTACTTCCCCTGATCTACCACCATCTGCTGCGGGCTGGCTATG TGCGTGCGGCGCGGGAAGTGAAGGAGCAGAGCGGCCAGAAGTGTTTCCTGGCTCAGCCCGTAACCCTTCT GGACATCTATACACACTGGCAACAAACCTCAGAGCTTGGTCGGAAGCGGAAGGCAGAGGAAGATGCGGCA CTGCAAGCTAAGAAAACCCGTGTGTCAGACCCCATCAGCACCTCGGAGAGCTCGGAAGAGGAGGAAGAAG CAGAAGCCGAAACCGCCAAAGCCACCCCAAGACTAGCATCTACCAACTCCTCAGTCCTGGGGGCGGACTT GCCATCAAGCATGAAAGAAAAAGCCAAGGCAGAGACAGAGAAAGCTGGCAAGACTGGGAATTCCATGCCA CACCCTGCCACTGGGAAGACGGTGGCCAACCTTCTTTCTGGGAAGTCTCCCAGGAAGTCAGCAGAGCCCT CAGCAAATACTACGTTGGTCTCAGAAACTGAGGAGGAGGGCAGCGTCCCGGCCTTTGGAGCTGCTGCCAA GCCTGGGATGGTGTCAGCGGGCCAGGCCGACAGCTCCAGCGAGGACACCTCCAGCTCCAGTGATGAGACA GACGTGGAGGGGAAACCCTCAGTAAAACCAGCCCAGGTCAAAGCCTCATCAGTTTCTACTAAGGAGTCTC CAGCAAGAAAGGCGGCCCCAGCCCCTGGGAAGGTGGGGGATGTGACACCCCAGGTCAAAGGAGGGGCCCT GCCCCCAGCCAAGAGGGCCAAGAAGCCAGAAGAGGAGTCAGAGAGTAGTGAGGAGGGATCTGAAAGTGAG GAGGAGGCCCCTGCAGGGACACGAAGCCAGGTAAAGGCCTCTGAAAAAATTCTCCAGGTCAGAGCTGCCT CAGCCCCTGCCAAGGGGACCCCTGGGAAAGGGGCTACCCCAGCACCCCCTGGGAAGGCAGGGGCTGTAGC CTCCCAGACCAAGGCAGGGAAGCCAGAGGAGGACTCAGAGAGCAGCAGCGAGGAGTCATCTGACAGTGAG GAGGAGACGCCAGCTGCCAAGGCCCTGCTTCAGGCGAAGGCCTCAGGAAAAACCTCTCAGGTCGGAGCTG CCTCAGCCCCTGCCAAGGAGTCCCCCAGGAAAGGAGCTGCCCCAGCGCCCCCTGGGAAGACAGGGCCTGC AGTTGCCAAGGCCCAGGCGGGGAAGCGGGAGGAGGACTCGCAGAGCAGCAGCGAGGAATCGGACAGTGAG GAGGAGGCGCCTGCTCAGGCGAAGCCTTCAGGGAAGGCCCCCCAGGTCAGAGCCGCCTCGGCCCCTGCCA AGGAGTCCCCCAGGAAAGGGGCTGCCCCAGCACCTCCTAGGAAAACAGGGCCTGCAGCCGCCCAGGTCCA GGTGGGGAAGCAGGAGGAGGACTCAAGAAGCAGCAGCGAGGAGTCAGACAGTGACAGAGAGGCACTGGCA GCCATGAATGCAGCTCAGGTGAAGCCCTTGGGGAAAAGCCCCCAGGTGAAACCTGCCTCTACCATGGGCA TGGGGCCCTTGGGGAAAGGCGCCGGCCCAGTGCCACCCGGGAAGGTGGGGCCTGCAACCCCCTCAGCCCA GGTGGGGAAGTGGGAGGAGGACTCAGAGAGCAGTAGTGAGGAGTCATCAGACAGCAGTGATGGAGAGGTG CCCACAGCTGTGGCCCCGGCTCAGGAAAAGTCCTTGGGGAACATCCTCCAGGCCAAACCCACCTCCAGTC CTGCCAAGGGGCCCCCTCAGAAGGCAGGGCCTGTAGCCGTCCAGGTCAAGGCTGAAAAGCCCATGGACAA CTCGGAGAGCAGCGAGGAGTCATCGGACAGTGCGGACAGTGAGGAGGCACCAGCAGCCATGACTGCAGCT CAGGCAAAACCAGCTCTGAAAATTCCTCAGACCAAGGCCTGCCCAAAGAAAACCAATACCACTGCATCTG CCAAGGTCGCCCCTGTGCGAGTGGGCACCCAAGCCCCCCGGAAAGCAGGAACTGCGACTTCTCCAGCAGG CTCATCCCCAGCTGTGGCTGGGGGCACCCAGAGACCAGCAGAGGATTCTTCAAGCAGTGAGGAATCAGAT AGTGAGGAAGAGAAGACAGGTCTTGCAGTAACCGTGGGACAGGCAAAGTCTGTGGGGAAAGGCCTCCAGG TGAAAGCAGCCTCAGTGCCTGTCAAGGGGTCCTTGGGGCAAGGGACTGCTCCAGTACTCCCTGGGAAGAC GGGGCCTACAGTCACCCAGGTGAAAGCTGAAAAGCAGGAAGACTCTGAGAGCAGTGAGGAGGAATCAGAC AGTGAGGAAGCAGCTGCATCTCCAGCACAGGTGAAAACCTCAGTAAAGAAAACCCAGGCCAAAGCCAACC CAGCTGCCGCCAGAGCACCTTCAGCAAAAGGGACAATTTCAGCCCCTGGAAAAGTTGTCACTGCAGCTGC TCAAGCCAAGCAGAGGTCTCCATCCAAGGTGAAGCCACCAGTGAGAAACCCCCAGAACAGTACCGTCTTG GCGAGGGGCCCAGCATCTGTGCCATCTGTGGGGAAGGCCGTGGCTACAGCAGCTCAGGCCCAGACAGGGC CAGAGGAGGACTCAGGGAGCAGTGAGGAGGAGTCAGACAGTGAGGAGGAGGCGGAGACGCTGGCTCAGGT GAAGCCTTCAGGGAAGACCCACCAGATCAGAGCTGCCTTGGCTCCTGCCAAGGAGTCCCCCAGGAAAGGG GCTGCCCCAACACCTCCTGGGAAGACAGGGCCTTCGGCTGCCCAGGCAGGGAAGCAGGATGACTCAGGGA GCAGCAGCGAGGAATCAGACAGTGATGGGGAGGCACCGGCAGCTGTGACCTCTGCCCAGGTGATTAAACC CCCTCTGATTTTTGTCGACCCTAATCGTAGTCCAGCTGGCCCAGCTGCTACACCCGCACAAGCCCAGGCT GCAAGCACCCCGAGGAAGGCCCGAGCCTCGGAGAGCACAGCCAGGAGCTCCTCCTCCGAGAGCGAGGATG AGGACGTGATCCCCGCTACACAGTGCTTGACTCCTGGCATCAGAACCAATGTGGTGACCATGCCCACTGC CCACCCAAGAATAGCCCCCAAAGCCAGCATGGCTGGGGCCAGCAGCAGCAAGGAGTCCAGTCGGATATCA GATGGCAAGAAACAGGAGGGACCAGCCACTCAGGTGTCAAAGAAGAACCCAGCTTCCCTCCCACTGACCC AGGCTGCCCTGAAGGTCCTCGCCCAGAAAGCCAGTGAGGCTCAGCCTCCTGTTGCCAGGACCCAGCCTTC AAGTGGGGTTGACAGTGCTGTGGGAACACTCCCTGCAACAAGTCCCCAGAGCACCTCCGTCCAGGCCAAA GGGACCAACAAGCTCAGAAAACCTAAGCTTCCTGAGGTCCAGCAGGCCACCAAAGCCCCTGAGAGCTCAG ATGACAGTGAGGACAGCAGCGACAGTTCTTCAGGGAGTGAGGAAGATGGTGAAGGGCCCCAGGGGGCCAA GTCAGCCCACACGCTGGGTCCCACCCCCTCCAGGACAGAGACCCTGGTGGAGGAGACCGCAGCAGAGTCC AGCGAGGATGATGTGGTGGCGCCATCCCAGTCTCTCCTCTCAGGTTATATGACCCCTGGACTAACCCCAG CCAATTCCCAGGCCTCAAAAGCCACTCCCAAGCTAGACTCCAGCCCCTCAGTTTCCTCTACTCTGGCCGC CAAAGATGACCCAGATGGCAAGCAGGAGGCAAAGCCCCAACAGGCAGCAGGCATGTTGTCCCCTAAAACA GGTGGAAAAGAGGCTGCTTCAGGCACCACACCTCAGAAGTCCCGGAAGCCCAAGAAAGGGGCTGGGAACC CCCAAGCCTCAACCCTGGCGCTGCAAAGCAACATCACCCAGTGCCTCCTGGGCCAACCCTGGCCCCTGAA TGAGGCCCAGGTGCAGGCCTCAGTGGTGAAGGTCCTGACTGAGCTGCTGGAACAGGAAAGAAAGAAGGTG GTGGACACCACCAAGGAGAGCAGCAGGAAGGGCTGGGAGAGCCGCAAGCGGAAGCTATCGGGAGACCAGC CAGCTGCCAGGACCCCCAGGAGCAAGAAGAAGAAGAAGCTGGGGGCCGGGGAAGGTGGGGAGGCCTCTGT TTCCCCAGAAAAGACCTCCACGACTTCCAAGGGGAAAGCAAAGAGAGACAAAGCAAGTGGTGATGTCAAG GAGAAGAAAGGGAAGGGGTCTCTTGGCTCCCAAGGGGCCAAGGACGAGCCAGAAGAGGAGCTTCAGAAGG GGATGGGGACGGTTGAAGGTGGAGATCAAAGCAACCCAAAGAGCAAGAAGGAGAAGAAGAAATCCGACAA GAGAAAAAAAGACAAAGAAAAAAAAGAAAAGAAGAAGAAAGCAAAAAAGGCCTCAACCAAAGATTCTGAG TCACCGTCCCAGAAGAAAAAGAAGAAAAAGAAGAAGACAGCAGAGCAGACTGTATGA Download Select all
CCDS ID	-

Protein Information

Protein ID	XP_005268563.1
Protein Name	Treacher Collins-Franceschetti syndrome 1
Molecular Wt. (Da)	152173
Protein Sequence	>6949 MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRK AEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAE TEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVS AGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGA LPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPP GKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK GAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPR KGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNIL QAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQ TKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEE KTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEE SDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVR NPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQI RAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQKDSNSKP ARSKTLAPAPPERNTEGSSESSEEELPLTQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKA RASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISD GKKQEGPATQVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSS SGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS QASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKG AGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWES RKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSL GSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESP SQKKKKKKKKTAEQTV Download Select all
Length	1488
Uniprot ID	O60443
Ensembl Protein ID	ENSP00000339587

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	1034
S	Phosphorylation	1151
S	Phosphorylation	1299
S	Phosphorylation	1301
S	Phosphorylation	1394
T	Phosphorylation	173
S	Phosphorylation	890
S	Phosphorylation	1073
S	Phosphorylation	1190
S	Phosphorylation	1338
S	Phosphorylation	1340
S	Phosphorylation	1433
T	Phosphorylation	173
S	Phosphorylation	967
T	Phosphorylation	173
S	Phosphorylation	829;-
S	Phosphorylation	906;-
S	Phosphorylation	906;-
S	Phosphorylation	1273;-
S	Phosphorylation	1312;-
S	Phosphorylation	1151;-
S	Phosphorylation	1190;-
S	Phosphorylation	1301;-
S	Phosphorylation	1340;-
T	Phosphorylation	504;-
T	Phosphorylation	581;-
T	Phosphorylation	581;-
S	Phosphorylation	304;-
S	Phosphorylation	381;-
S	Phosphorylation	381;-
S	Phosphorylation	156;-
S	Phosphorylation	156;-
S	Phosphorylation	156;-
T	Phosphorylation	456;-
T	Phosphorylation	533;-
T	Phosphorylation	533;-
S	Phosphorylation	506;-
S	Phosphorylation	583;-
S	Phosphorylation	583;-
S	Phosphorylation	153;-
S	Phosphorylation	153;-
S	Phosphorylation	153;-
S	Phosphorylation	1333;-
S	Phosphorylation	1372;-
S	Phosphorylation	531;-
S	Phosphorylation	533;-
S	Phosphorylation	534;-
S	Phosphorylation	537;-
S	Phosphorylation	538;-
S	Phosphorylation	540;-
S	Phosphorylation	543;-
S	Phosphorylation	608;-
S	Phosphorylation	610;-
S	Phosphorylation	611;-
S	Phosphorylation	614;-
S	Phosphorylation	615;-
S	Phosphorylation	617;-
S	Phosphorylation	620;-
S	Phosphorylation	608;-
S	Phosphorylation	610;-
S	Phosphorylation	611;-
S	Phosphorylation	614;-
S	Phosphorylation	615;-
S	Phosphorylation	617;-
S	Phosphorylation	620;-
T	Phosphorylation	609;-
S	Phosphorylation	616;-
S	Phosphorylation	617;-
S	Phosphorylation	618;-
S	Phosphorylation	619;-
S	Phosphorylation	622;-
T	Phosphorylation	686;-
S	Phosphorylation	693;-
S	Phosphorylation	694;-
S	Phosphorylation	695;-
S	Phosphorylation	696;-
S	Phosphorylation	699;-
T	Phosphorylation	686;-
S	Phosphorylation	693;-
S	Phosphorylation	694;-
S	Phosphorylation	695;-
S	Phosphorylation	696;-
S	Phosphorylation	699;-
S	Phosphorylation	233;-
S	Phosphorylation	233;-
S	Phosphorylation	800;-
T	Phosphorylation	785;-
T	Phosphorylation	779;-
S	Phosphorylation	813;-
T	Phosphorylation	806;-
T	Phosphorylation	856;-
S	Phosphorylation	890;-
T	Phosphorylation	883;-
S	Phosphorylation	877;-
T	Phosphorylation	862;-
T	Phosphorylation	856;-
S	Phosphorylation	890;-
T	Phosphorylation	883;-
S	Phosphorylation	877;-
T	Phosphorylation	862;-
S	Phosphorylation	794;-
S	Phosphorylation	798;-
S	Phosphorylation	875;-
S	Phosphorylation	871;-
S	Phosphorylation	875;-
S	Phosphorylation	871;-
S	Phosphorylation	793;-
S	Phosphorylation	791;-
S	Phosphorylation	868;-
S	Phosphorylation	870;-
S	Phosphorylation	868;-
S	Phosphorylation	870;-
S	Phosphorylation	164;-
S	Phosphorylation	164;-
S	Phosphorylation	164;-
S	Phosphorylation	198;-
S	Phosphorylation	200;-
T	Phosphorylation	203;-
S	Phosphorylation	204;-
S	Phosphorylation	205;-
S	Phosphorylation	206;-
S	Phosphorylation	207;-
T	Phosphorylation	210;-
S	Phosphorylation	198;-
S	Phosphorylation	200;-
T	Phosphorylation	203;-
S	Phosphorylation	204;-
S	Phosphorylation	205;-
S	Phosphorylation	206;-
S	Phosphorylation	207;-
T	Phosphorylation	210;-
S	Phosphorylation	88;-
S	Phosphorylation	83;-
T	Phosphorylation	84;-
S	Phosphorylation	85;-
S	Phosphorylation	87;-
S	Phosphorylation	88;-
S	Phosphorylation	83;-
T	Phosphorylation	84;-
S	Phosphorylation	85;-
S	Phosphorylation	87;-
S	Phosphorylation	88;-
S	Phosphorylation	83;-
T	Phosphorylation	84;-
S	Phosphorylation	85;-
S	Phosphorylation	87;-
S	Phosphorylation	398;-
S	Phosphorylation	400;-
S	Phosphorylation	401;-
S	Phosphorylation	402;-
S	Phosphorylation	405;-
S	Phosphorylation	407;-
S	Phosphorylation	482;-
S	Phosphorylation	484;-
S	Phosphorylation	475;-
S	Phosphorylation	477;-
S	Phosphorylation	478;-
S	Phosphorylation	479;-
S	Phosphorylation	482;-
S	Phosphorylation	484;-
S	Phosphorylation	475;-
S	Phosphorylation	477;-
S	Phosphorylation	478;-
S	Phosphorylation	479;-
S	Phosphorylation	171;-
S	Phosphorylation	171;-
S	Phosphorylation	171;-
S	Phosphorylation	505;-
S	Phosphorylation	582;-
S	Phosphorylation	582;-
S	Phosphorylation	298;-
S	Phosphorylation	375;-
S	Phosphorylation	375;-
S	Phosphorylation	920;-
S	Phosphorylation	913;-
S	Phosphorylation	915;-
T	Phosphorylation	916;-
S	Phosphorylation	919;-
S	Phosphorylation	992;-
T	Phosphorylation	993;-
S	Phosphorylation	996;-
S	Phosphorylation	997;-
S	Phosphorylation	990;-
S	Phosphorylation	922;-
S	Phosphorylation	924;-
S	Phosphorylation	921;-
S	Phosphorylation	1001;-
S	Phosphorylation	998;-
S	Phosphorylation	999;-
T	Phosphorylation	933;-
T	Phosphorylation	937;-
T	Phosphorylation	1010;-
T	Phosphorylation	1014;-
S	Phosphorylation	1180;-
S	Phosphorylation	1219;-
S	Phosphorylation	1150;-
S	Phosphorylation	1189;-
S	Phosphorylation	1153;-
S	Phosphorylation	1192;-
S	Phosphorylation	864;-
S	Phosphorylation	855;-
S	Phosphorylation	857;-
S	Phosphorylation	858;-
S	Phosphorylation	859;-
S	Phosphorylation	862;-
S	Phosphorylation	932;-
S	Phosphorylation	934;-
S	Phosphorylation	935;-
S	Phosphorylation	936;-
S	Phosphorylation	939;-
S	Phosphorylation	941;-
S	Phosphorylation	1113;-
S	Phosphorylation	1124;-
S	Phosphorylation	1152;-
S	Phosphorylation	1163;-
S	Phosphorylation	107
S	Phosphorylation	107
S	Phosphorylation	107
T	Phosphorylation	249
T	Phosphorylation	249
T	Phosphorylation	233
T	Phosphorylation	239
T	Phosphorylation	310
T	Phosphorylation	316
T	Phosphorylation	310
T	Phosphorylation	316
S	Phosphorylation	369
S	Phosphorylation	446
S	Phosphorylation	446
S	Phosphorylation	426
S	Phosphorylation	503
S	Phosphorylation	503
S	Phosphorylation	685
S	Phosphorylation	687
S	Phosphorylation	688
S	Phosphorylation	692
S	Phosphorylation	694
S	Phosphorylation	762
S	Phosphorylation	764
S	Phosphorylation	765
S	Phosphorylation	769
S	Phosphorylation	771
S	Phosphorylation	762
S	Phosphorylation	764
S	Phosphorylation	765
S	Phosphorylation	769
S	Phosphorylation	771
S	Phosphorylation	700
S	Phosphorylation	777
S	Phosphorylation	777
T	Phosphorylation	1033
S	Phosphorylation	1037
S	Phosphorylation	1039
S	Phosphorylation	1076
T	Phosphorylation	1102
T	Phosphorylation	1104
T	Phosphorylation	1141
T	Phosphorylation	1143
T	Phosphorylation	1109
S	Phosphorylation	1114
T	Phosphorylation	1148
S	Phosphorylation	1153
T	Phosphorylation	1157
T	Phosphorylation	1196
T	Phosphorylation	1281
T	Phosphorylation	1320
S	Phosphorylation	1330
S	Phosphorylation	1369
T	Phosphorylation	1145
T	Phosphorylation	1184
T	Phosphorylation	168
T	Phosphorylation	168
T	Phosphorylation	168
S	Phosphorylation	178
S	Phosphorylation	178
S	Phosphorylation	178
T	Phosphorylation	906
T	Phosphorylation	983
S	Phosphorylation	1309
S	Phosphorylation	1348
S	Phosphorylation	1357
S	Phosphorylation	1396
S	Phosphorylation	724
S	Phosphorylation	801
S	Phosphorylation	801
T	Phosphorylation	317
T	Phosphorylation	394
T	Phosphorylation	394
S	Phosphorylation	1284
S	Phosphorylation	1323
S	Phosphorylation	707
S	Phosphorylation	784
S	Phosphorylation	784
T	Phosphorylation	144
T	Phosphorylation	144
T	Phosphorylation	144
T	Phosphorylation	728
T	Phosphorylation	805
T	Phosphorylation	805
S	Phosphorylation	227
S	Phosphorylation	304
S	Phosphorylation	304
T	Phosphorylation	837
T	Phosphorylation	914
T	Phosphorylation	914
T	Phosphorylation	1038
K	Acetylation	678
K	Acetylation	755
K	Acetylation	755
K	Acetylation	523
K	Acetylation	600
K	Acetylation	600
K	Acetylation	219
K	Acetylation	296
K	Acetylation	296
K	Acetylation	155
K	Acetylation	155
K	Acetylation	155
K	Acetylation	1337
K	Acetylation	1376
T	Phosphorylation	996
T	Phosphorylation	586
T	Phosphorylation	663
T	Phosphorylation	663
S	Phosphorylation	333
S	Phosphorylation	335
S	Phosphorylation	336
S	Phosphorylation	337
S	Phosphorylation	340
S	Phosphorylation	342
S	Phosphorylation	410
S	Phosphorylation	412
S	Phosphorylation	413
S	Phosphorylation	414
S	Phosphorylation	417
S	Phosphorylation	419
S	Phosphorylation	410
S	Phosphorylation	412
S	Phosphorylation	413
S	Phosphorylation	414
S	Phosphorylation	417
S	Phosphorylation	419
T	Phosphorylation	897
T	Phosphorylation	974
S	Phosphorylation	597
S	Phosphorylation	674
S	Phosphorylation	674
T	Phosphorylation	1305
T	Phosphorylation	1344
S	Phosphorylation	478
S	Phosphorylation	555
S	Phosphorylation	555
S	Phosphorylation	479
S	Phosphorylation	556
S	Phosphorylation	556
S	Phosphorylation	472
S	Phosphorylation	549
S	Phosphorylation	549
S	Phosphorylation	624
S	Phosphorylation	701
S	Phosphorylation	701
T	Phosphorylation	1072
S	Phosphorylation	110
S	Phosphorylation	110
S	Phosphorylation	110
T	Phosphorylation	230
T	Phosphorylation	230
S	Phosphorylation	433
S	Phosphorylation	510
S	Phosphorylation	510
T	Phosphorylation	594
T	Phosphorylation	596
S	Phosphorylation	601
T	Phosphorylation	671
T	Phosphorylation	673
S	Phosphorylation	678
T	Phosphorylation	671
T	Phosphorylation	673
S	Phosphorylation	678
S	Phosphorylation	905
S	Phosphorylation	982
T	Phosphorylation	1193
T	Phosphorylation	1232
S	Phosphorylation	1396
S	Phosphorylation	1435
T	Phosphorylation	108
T	Phosphorylation	108
T	Phosphorylation	108
T	Phosphorylation	167
T	Phosphorylation	167
T	Phosphorylation	167
T	Phosphorylation	873
T	Phosphorylation	950
T	Phosphorylation	1077
T	Phosphorylation	147
T	Phosphorylation	147
T	Phosphorylation	147

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
1459	CSNK2A2	279	NP_001887.1	in vivo	10982400
5111	PCNA	1456	NP_002583.1	in vitro	12171929
7343	UBTF	2814	NP_055048.1	in vivo;yeast 2-hybrid	15249688
10528	NOP56	10119	NP_006383.2	in vitro	12777385

Pathway Information

Pathway Name	Pathway ID
Ribosome biogenesis in eukaryotes	hsa03008

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
smart00667	Jun-37	LisH
cl23059	Jun-37	LisH superfamily
pfam03546	387-905	Treacle
pfam03546	118-567	Treacle
pfam03546	212-510	Treacle
PHA03247	157-535	PHA03247
PHA03247	234-676	PHA03247
PRK07003	234-499	PRK07003
PRK12270	385-467	kgd
PRK07003	214-463	PRK07003
PRK07764	177-465	PRK07764
pfam03546	883-948	Treacle
PRK12323	309-541	PRK12323
PRK12323	250-469	PRK12323
PRK12270	378-465	kgd
PRK14951	319-456	PRK14951
PRK12323	423-605	PRK12323
PRK14951	373-467	PRK14951
PRK12323	302-495	PRK12323

Ontology Information

HPRD ID	2303
Molecular Class	Transcription regulatory protein
Molecular Function	Structural molecule activity (GO:0005198)
Biological Process	Cell growth and/or maintenance (GO:0008151)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO