CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
TIMP2	7077	TIMP metallopeptidase inhibitor 2	17	CSC-21K

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
21478099	2010	Cell line : - Source : Second General Surgery Department of the Biaystok Medical University Hospital Sample Type : - No. of Sample : 210 subjects 91 previously untreated colorectal cancer (CRC) patients, 28 patients with colorectal adenomas (CA) and 91 healthy subjects Stage : -	ELISA	Down-regulation	-	TIMP-2 may usefull as a biomarker in the diagnosis of CRC, especially in combination with CEA. However, further investigation is necessary. Serum levels of MMP-2 and TIMP-2 were significantly lower in CRC patients than in healthy subjects and decreased with tumor stage.

Gene Details

Chromosome 17 - NC_000017.11 (78852977..78925390, complement)
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Gene Type	protein coding
Gene Family
Description	This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
Chromosome	17
Location	17q25
Start	78852977
End	78925390
Strand	-
Gene Sequence	>gi\|568815581:c78925390-78852977 Homo sapiens chromosome 17, GRCh38.p2 Primary Assembly CGCAGCAAACACATCCGTAGAAGGCAGCGCGGCCGCCGAGAACCGCAGCGCCGCTCGCCCGCCGCCCCCC ACCCCGCCGCCCCGCCCGGCGAATTGCGCCCCGCGCCCCTCCCCTCGCGCCCCCGAGACAAAGAGGAGAG AAAGTTTGCGCGGCCGAGCGGGGCAGGTGAGGAGGGTGAGCCGCGCGGGAGGGGCCCGCCTCGGCCCCGG CTCAGCCCCCGCCCGCGCCCCCAGCCCGCCGCCGCGAGCAGCGCCCGGACCCCCCAGCGGCGGCCCCCGC CCGCCCAGCCCCCCGGCCCGCCATGGGCGCCGCGGCCCGCACCCTGCGGCTGGCGCTCGGCCTCCTGCTG CTGGCGACGCTGCTTCGCCCGGCCGACGCCTGCAGCTGCTCCCCGGTGCACCCGCAACAGGCGTTTTGCA ATGCAGATGTAGGTAAGGAGCGGCGACCCCAGCCCCCGCGCGGGGCCCCACCTCCCCCGCGACCCCGAGG GTTCGCAGACGCCCCGCCCGCCCGCCGCTGGCCGAGGGACCCCAGCGCCCGCCTCCTGGTCCCTCGGCGC CTTCTCGAATCCTGCAAGTGGACGCCCAGAGCCGACTTTCTTTCCCCCCTCCCTCCTCTCCCTTTCTTTC CCTCTCTTTGCCGAGATGCGTCTCAACCTCAAAATTCCACCGAAATTCCGCCGCAGCTCCAGCCCCAGGA AAGGGAGCCAGTTTGGCTTTTGGCAGGCGGCGCGCCCTGGGATGCCAGCGCTGGGGGCGGGGAGCGTGGG GGACACGGCGTGGGGGCGGGGGGCTGGAGGACTGGGGACCCCAGGAAGAAACTTTCGCAGATAAGGTGGG AGTTGGGCTTCTCTGGGCTTGGGGCTGGGTGGGGAAGGGCTTCTCTGCTGGGGCTTCTCCCACCAGCCCC ATTTGGGGGCTCCCCGATCAAGCCAGGGTGGGATGGAAGCCCGCCCTACCCGAGGCAGGTTCCACAGGCC CAGAGGGGCAGGTGAAAAAGCCGGTGGCGTCTCCTGGCGTGGCTCCTTGCTTGCGCCCTGCCCAGGAGGC CCTGCAAACTGGCTGGGCAGGGACCGGGACCCCCGAATGTTCCGCTTTTTCGGGACGTCCACAAAAGCTG GAGACTTTGGTGACCGGACCCGGCACGTGGGACTGTGCTGCTGCTCAGATTCCCCAGCAAATACCCATGA CCTCCGGACTCCTAGCCCCCAAAAGACAGGCGCCATGGAGGGAGGCAGGAGGGGCCCAGTTATTTGTTCT GATCCATGGAGGGGGAGGACCAGCAGAAATGGGAGGAACCCGCTGGCTCGAAGTTTCCACCCTGGTCCTG CACCTCAAGCCTCTGCAGCCCTGGTGCTGGTCAGCATGGTTTTCCTGGGGCAAGTCTGGCTACACGGCAG GTGGTCTCGGAGCCCCCTGCCCTCCTTCCTTCTTATGTCTGAGTCTCAGTCGAGTGACCTGTCCAGGGCA GATGGAGCAAGGCGGGGGCCCCCTCACCTGCCCAGAGTGGAGGTGGGACTTTCTGTTTCTCCTGCTGTCA GCCACGCCCTTCCCATACCCCGCCCACGGCTTCTTGCCCCACCCCGGTTAGCCCTAGGAGCTGCGTGCCC AGCTGGGGAAGTTTTCAGTTGCACCAATCTATTGAGATCACAGGTCTCAGGTGGCTCAGGCCACCTGGGC GGAAGGCTTGGTGTGTGCCTGTGTCAGTTTCCACAAAACCCAGTTTGGGGGAAATGAGGTCTTTTCTCCA GTTTAGCCTTGGTGCTCAGCAAGATTTGTGGGTGAAGGAGAGGTTCCTTTGATGAGGGAGCCATAATGGG CCTTTCTCTGGGGGTCCACGAGGAGTGCAGGCCTGTCCAGGCTCCTTGGCTCACCAGCACGTGCTGGGGC AGGATGTAGCCAAGGCCCAGAAGGAGGCTGTGGATAAAAGGACCTGGGAGTTGGATTTGTAGGAGTTGGG CCTTGGGACCCCTCCCCCTCCCGCCCCCCCCCCCACCCCGCCCCACACACACACTCCTCAGCTGTGTGGG AGAATGTCCAGGCAGCCACTCTGTCCTTGCTTGGCATAAGTTAAGGCGGCCACTGAGCTGGGAGCTGTTT CTGCGTGGGGTGTGGATCCAGGATGGCAGAGGGTGGAGGGCTGCAGTGCGTGCCTCCCGCCTCCTTCATG CTCAGCGCAGCACTCTCCTCTTCTGGGTTGCCTGGCATTTGTGTCTAAATCTTTGCATCAAAATCATCCT GTAGCTAAAACTTTTCACCCCATCCCGGCTCAGAGGCCCAGTCAGATGCCAGAGTTGCACTGCAGAGCTC AGGGCATTCGCTTCCTGTGGCCGCTGTGACAAACTACCACAAATGGGAGGGCTTAAAAGAACAGGAATCG ATTCTCTGTAGCTCAGGAGGCCAGAAGTCTGAAAAGGTGTCCACAGAGCCAGTTCCTTCTGGGGGCTGTG AGGGAGAATCTCTTCCAGGCCTCTCTCCTTGATGTTGCTTGGTTCCATTTTCAAGGAACACATCACTTCC ATTTCCGCCTGTCTTCACATGGCCTTCTCTCGTGTGTCTCTGTGTCCAAATTTCCCTGTTCTTTTTTTTT GGAGAGCAGGCTGGAGTGCAATGGCGCAATCTCGGCTCGCTGCAGCCTCCGCCTCCTGGGTTCGAGCAAT TCTCCTGCCTCAGCCTCCCAAGTAGCTGGGGTTACAGGCACCTGCCACCACACCCGGCTAATTTTTTGTA TTTTTAGTAGAGACAGGAATTCGCCATGTTGGCCAGGCTGGTCTCGAACTCCTGGCCTCAGGTGATCCGC CTGCCTCAGCCTCCCAAAGTGCTGGGATTATAGGCGTGAGCCACCGCGCCCGGCCAAATTGCCCTGTTCT TCTAAGGACAGCAGCCATTGGATTTAGGGCCCACCCTAATCCAGTATGACTTCATCTTGATAGATCAACA AATACTCTATTTCCAAATAAGGTCATATTCATAGGATCTGACTAGATGTGCATTTGAGGGGGGACGTAAT TCAGCCCATACACCAGGCTGCCTTCTCTTATTCCCAGTCACCCTTTCCGTGCTCAACCAACTTGGGATAA ACAACCCAGGACATCCCAGGGTAGGGTCCCGGAACAAATCCCACAGGGACGACAGCGGCCTGTCTATTCT CCAGTGTTCGATTCTCCTCGAAGCGATGCAGGTTTGTGACTTTCTCAGCAATGGTTCCCCATTCTGGCTC AGAGCAGAATTGCCTGGAAGATTCTTAAAGATTGCTCAGGTCTAGGTCCCTTTGCAGATACAGAGGGTCT TGCTCAGACTTCGGCTTTTGCAGTTTTAAAAGGCCCACAGGTGATTTAACCAGGGCTGTGACCCAGGGGT CTCAGAAAGGGGGTACAGTGGAGGTTAATAAAGGCTGGCTTGTTATGTGGCAAGCTGGCTCCTTTTACTC TTGGCTGCATGCAGCCTTGTTAAATGGCTTGGTGTCTACAAGAGGCAATTGGCTTAAGAAACAGTCAGAT TTCTGTCTGCCCGGCTGAGGATTTCTGGGAGGTATCTCCCTAGCAGCTCTTGCAGTTGGTAGGACCGGAA CTGTGGTCGGCAAAGATAATTCATGATGAGGTGGTGATGTTTAGGATAAGGGATGGTAAGAGGTGACCTG ATTTCTTCCTGGAAGGCCCCAGGTCCTTGTCCTTTCCAGCAAGGCCAGCACAAACGGGAAGCATTTTGTG TCTCAGTTACAGTACTGTTCAAATGCGCTGCTGGCCCGGCTCCCTCTCACCCAGTGAAATCCTTCACATC TACTGCCAGCCTGCACAGCTACAGGGATCTGGCTGGAAATTAGCTTTGGGCTCACCATTCAGGCAGTCCC ATGCCTGGAGCCACTTAGCCAGCTGAGCTACTTGGCAGACTCGGGCTGCTTGGGCCCGTTTCTGGACTCA AGGGTAAAGCCAGGAGCTCTCTGGATGCAGAGAATAAAACCTCTCCTCTGGCTTGGGTGGCAGTACCTAA GGCCACACATTATCCTAGAAGACCTCTGCGATGACATCTTCCTCACATGTTCCCACCTCCAGAAACTGTC CTCTGCAAATCCCCCGAGGAGCTCCAGCTCCAGCTAGAGAGGGGTCCACAACCAAGAGGGGGAACAACTG CTATTTTCTGGGGTGAACAGCCAAGGGTGACCTGGTTCCTGGGGGACACAGTGACAGGGACCAGACAGAT AGTAGGGGCCACCCCAGAAAACACACAGCACGCAGTCAAAAATGGCTCTGTCTTCAGGACACGTGCTCAG GAAAAGCAACACAGCATCAGATTCATGTGAGCTGGGTCAGGCCTTCCATGCGAGGGGGCGGCGTGGCGCT TTTTAAAGAAACTGTTGGCAACTCGTTGTGCGAAGTATGTGATCGATCTGTATTGTCAGTTTTGTTCATC TTGATTTTCATATTGGGCTTGTCTGTGTTTCAACAAGCAATTATGGAGTGGCTGCCTCTGCCCCCGGGGA TGTAAGGGAGAAGCAAGACATTGTCCCTGTGGTGGGGGATGCAGGGGGTGGTACATCTTGGCACCAGGCG GTGTGGAAGGGGGTTCCTGCTGCCCGGCGTGGTGAGCAGGCCTCCCCTCCTCAACTGCCCAGGTGTGGTA TAAAGTCAGTCCACTCAGTGTGGTTTCGGTAAATAATTAACAACAGATAAACTTTCGAAATAACCAAAAT TCAGGAGTAATCATGTGACAATGTGAAATGCATTTGCAAGATGTGAGGATAGAAGGCCCCATGGTAGGTT GAGGAGGGAGCTGTGGGGAGAACTGAGGCTCTTCGGCTTGGTTTTGAACAGCGTCCTTGGAGGGACAGGA TCTGTCAGGGGAGTCACTGACCCCTGAATTACTGGCAGCTCCCAAGGCAGGGGGACTGGAAGAGCAGGGA GAGCTGTGCACAGCCTGGAGGTATGGCAGGTGCTGGAAGGAGCTCTCTGGACAACACACGTTTCTCCCTA TCTGGGATCTGAGGACAGTGCCAGCCTCAGAGCCTCTCGGGCCTCCCCTATTTGCACCCTTCTGGGGGTG CAGAGCCACGTACGCAGTCCTGGCCTGTCGTTTGTGAGCTGCAGGTGGGCTTGGGTACTGCCTCCCTCCT CCCTGCTGTCGCAGCCAGGTTGCTAGGTAGATGCCACTGGTGTGGGCTGAGAGGTTCAGACTCTGTGGCG ACATCTGAGCACATGGAGAACAGGGCATAGATGACTCCTGGGAGACTGAGAGGCGCGGGCAGCCGTCTCC AGTCCTGATGCAGAACCACTGACTCGATGCAGTGGGGGTCGTGTGTAGGGGTGAACGTCTTGGGTTCGGA AACAACAAAGAGGTCTGCCCGAGGCTTCCCAGGCAGCTGCGAGGAGGGATGCAACAGCAGGGAGGAGGAG ATAAGAAGGAAGCAAAGACAGGCAGACGTGGCAGTGGCAGGGGCAGGAGGGGTGCATGCCCTGGACACTC TCTCTGTCCCCCGGTGCACGCACAGGCTCACAAACCAGGGACGGAGGGCAAGTGGCTGCATGGCTAGGAT GGTCTTCTTTTCTTTTTCTTTTTTTTCGAGATGGAGTCTCACTCTGTCTCCAGGCTGGAGTGCAGTGGCG CTATCTTGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGC TGGGACTACAGGTGCCCGCCACCATGCCCGGCTAATTTTTTTGAATTTTTATTAGAGACGGGGTTTCACC GTGTTAGCCGGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTCGGCCTCCCAAAGTGTTGAGA TTACAGGCTTGAGCCACCGCACCCAGCAGATGGTCTTTTTCAAGAGGGGAGGGCAGAGTGAAGAAATCAA GGTAAGGGAGGGTGAAGAAGCCGCATCTGGAGGACGGCACTGGGGACCGTAACCCCTGGTCATTTAGCGG CAGCAGGGTGGGGTGTGCACAGGTGTTCTAAGCCAAGGGACCAACTGCCCCAGGAAAGGTGAGAGTTCTG GGTACAGAGTAGGCCAAAGAGGAGCCTGGGGATTCAGGGGGACCCACAAGGAGATTGGGGCCAAATGTCA CGGCTCTGGCTTGTCATGTGACATCTGCATTCCATCCCGGGACCCACGCAGCCACCAAAGATGTTCTGGC TGTGGAATGACAGCGGGCGTTGCCCAGGGAGCCTGGTAGAAGGCAGCCGCCTAACTCCGCGTGCTGGAGC GGGCCTGGGGGTGGCACTGGAGTTTCAGGACTCTCCAGGTGCTGCTGCCGCCCGCCAAAGTTGGCATAGA CCAGTCGTCTCCGGAGGGGTGCCCAGTACAGCCTCGGTGCTAAGAATGTTATGAATAGTTAGCATATGGA TTCAGAGTTGTACTCCAAATATAATTTTTTTTTTTTTTTTTGAGACGGAGTCTTGCTGTGTCACCCAGGC TGGAGTGCAGTGGTGCAATCACAGATCACTGCAGCTTCAATTTCCTGGCCCAAGCGATTCTCCCACCTCA GTCTCCCAAGCAGCCACCACGCCCAGCTAATTTTTTTAATTTTTTGTAGAGATGGGGTTTCGCCATGTTG CCCAGGCTGGTCTCGAACTCCTGAGCTCAAGTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGGGATTAC AGATGTGAGCCACGGTGCCCGGCCTATATATACTTTTTTAATGAATATCTGATATTGTGAGTGCTTGGCC AAGGTTTTGTTTTTGTTGCCCGTGGGTCTGAACAGAAAGTGTGGAGGCTGACCACCTCAGTGTCGGGGGG TGGAGTAAGCAGGCAGATGAGCTGCCCTGAGATTGCTGGGAGGAGGGAAGGCGGGCAGACCCAGACTTCC CAATGGAGAGATGGTCAGGAGCATGGATGTCTCAGAGTGGCAGGCAGGATGAAGCTGGTGTCCCCAGGAC CTCCCAGGGCCCACCTGCCTGGACCCCTGCAGCCTGTGCCCTGACGCCCTGGTGCCCTCGTGCATTTGCT GGGACGTGGCTGTGCAGCGGCAGAGGGAAGGGCACAGAGACCCCGCCCCGATGATTCCCACCTTACAACT GAGGGCTGAGCTACTCCCCAGTCAGCCAGGTCAGACTGGAGCCCAGGGAAAGCTTCCGGAGCCCCAGCAA GTCAGGTTGAGAGTGTGTTTACGCTAAGAAGCAAATTGAGGAACAGTCTTTATAAAAGAGGGGTCCTAAC CCAGAGTGTGTGAACACCCAGCCAGAGATAGGCCTGGCGGGTTTGGGGGTGGTCACAAGCCCGGAAACTG TAAGTGAAGTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGTGTGTGCACGCGTACGTGTTTT TTTTGTGGACAGTGGCAGCCGCCAACTTCTCAAAGGTGCCTGTGGCCCTCCAAACGTCAAGTCACTGCCA TTTAAAAGGAGTCTTTTTATAGGTTTCGAGTCTTCTGTTTCTTGTGAGTATCTGCCTAGTCTCGGAGCTG AGCGATGGTAACGATCTTGCCTTTCTCTCCTCTTCCACCCTCATTCTGCACTCGGCCGCCCTGGGCAGCC AGGATCCGCTCAGACACTACCACCACGAGGGGAGTCCGAGGCAGACCTGTAACCAGCTCTGGGGAAAGGA TGCCATCAGTGTCCTTTGGCCTCCTAGCTGGTCTCAGGGATGGCTCCAAAGACCTGGGAGGTTCTGTGGT TGTCTTCCATGGGGAAGACGTCCTTGGTAGACGGCAGCTGCTCTTTGATCTCAAACTCTGATCACAGCTG GACCACACATGGCCTGAGGGAACTCCAGACCTCACCAGTTAGGAAGGGCCTGGTGTCTATGTCTTAGATA CCTGCTTCTTACAGAATTTATTCACTTAAGTGTTTTTATATTTTGTTTTACAATAGAATTTGGGTGCCTA CCGTACACAGAAATACTATGGCAAGTGTGTCAAGGAATTATTTAGTTTTCTGAGACGGAGTTTTGCTCTG TCGCCCAGGCTGGAATGCAGTGGTGCGATCTTGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCAATT CTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGTGTGTGCTGCCATGCCCAGCTAATTTTTGTATT TTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGGGATCTC GGCTCACTGCAAGCTCCGCCTCCTGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACT ACAGGCGCCCGCCACTACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCCTGTCGGC CAGGCTGGTCTCAAACTCCAAAGCCATGGTGCCCATCTTCAAGGAAGTGAGCGCAGGAATGCGAAGATCA TCTTGCAGGCTGCACCTCTTGCTAGAGACTCTTACCGAGGTTAGGACACTGTTGAGATTGTGGGCCCTGA GGGGTGGATCTTATCAGAGCTAAGATAAGCCCCGAGGAAAGGTCCTGGGGTGGGTATGGGGAGCCCAGGG TGGCTGTGGTAGAGAGTGTACCACAGGGGGACAGAGTCATTAGAACAAAGTATGGCCAGGCTTGAGCCCA GGTGGAGCAGCAAAGCCTGGAGGCCCGGCAGTGGGACCTGGCAGTGGGACTCCGGGGAAGGCTTTATGGC CCCTGCACTGGGGGAGAGGGGGCAGACAGGAGGGGGATGACACTGAGGAGGAAGGTGGTGTTGAGAGGCT CGCAGTTACCAGGGGAGCAGAGCTCCCACCTGCACTGGGGAAGACCCAGGAGATGGAAGGCAGGCCCTGA GCGGGGCCATGGGTCGCGGGCAGACACAGGAGATGCCTCTGGAGCTTGACCCAGTGCCTGGGAGCCAGAT GCCCTCTAACCTGGTCAGGAGCTCAGGCGGGTAGAGGTCTCTGTTGAGTTCTGCTGGAATCTGGTGACCA GAAAGTCTCGGCGAGAGGGATTTGAGCTAGAACTTCAGCAGACAGTGGAAATTGTGTAACGGGGCCTTGG AGGGAACAGGAAACGGAGCATTGAGGGGGAAGGGAGCCAGCAGTAGCGAGGGGAACTGACATTCATAGCA AACAGGGTGAGCGGGGGTCAAATGCTGGCCCCAGATTGAGTCCAGCAGAGCGATCCGGGACAGGTGGCCT CTCTCTGCCCCCACTTCCACACCTCCAAAAAGGAGAGGCGAATTTCCTGCCTCCCAGGAAGCTCTCGGAG CTAGTGGGGGACACCAGCTCTTTCTGCATCAAACCCTGGCTCTCCCTGTCTTTGTGTTCTTGTTCCTCCC CACCCCGCCCTGAGGGAGGCCTGGGAGCAGCCAGGGAGGTGAATCATGACATGGTGATAATGACTATGGC AACAATAACAGCTGGCAGAGGTGCCAAGGGCTTGGAGGTATGTTCTTGCTCTTCACTAGTGTCAACCCAT TTCCTTCCCTATCCTCATCCCCATTGTACAGACGATCCAACGGAGGCACAGGCCCACTAAGGAACCTGCT CAGGGTTAGCTGGCTAGGAAATAGCAGAGTAAAAGAAGAGATGGTTTTTAGGCCGGGCACGGTGGAATCA TGCCTGGAATCCCAGCACTTGGGGAGGCCGAGGCATGTGGATCGCCTGAGGTCGGGAGTTCAAGACCAGC CTTGCCAACATGGTGAAACTCCATGTCTACTAAAAATAAAAAAATTAGCTGGGCGTGGTGGTGCACGCCT GTAATCCCAGCTACTCGGGAGGCTGAGGCATGAGAATCGCTTGAACCTGGGAAGCAGAGGTTGCAGTGAG CCGACATCGCACCACTGCACTCCTGCCTGGGTGACAGAGTGAGACTCTGTCTCAAAAAAAAAAAGAAGAA AAAAAGAGAGAGAGACGGCTTTTAAAAGGAGGTACATCAACAGAATGGTGCTGATTCAGACTGATACTGG CTTGGGGATGAATGGTCTAGGCTGTGGAGCTGGGCTGAAGCTCTACAGGTGACGGATGGAGCCACTGAGG AGGGAGAGGAGCTCCTGAGGCTGGCCTTGTTCATGAGGTTTGCCTGTCTGCTGGAGATAAGCTAAATCAA TTAATCTTTCTCCCTGCCGCAACAGAGTGAGCAGACATTTCAAATGATATTACAGATTTGTGTTTATGAC CTAGAAAAATGTTCAGAGCACAGTACTTTCAAAAGCCCAGACTGGGCCGGTTGCAGTGACTCACGCCTGT AATCCCAGCACTTTGGGAGGCTGAGGTGGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCA ACATCATGAAACCCCATCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGCGGGCACCTGTAATCC CAGCTACTCAGTAGGCTGAGGCAGGAGAATCACTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCCGAGAT CGTGCCACTGCATGCCAGCCTGGGCAACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAGAAAAAGCCCA GACTGGCCAGGCGCGGTGGCTTACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGAGGATCACTT GAGCCCAGGAGTTCCAGATCAGCCTAGGCAACATAGCAAGACCTCATCTCTACATAAAATAAATTAAAAT TTTAAAAATTAGCCAGGGGTGGTGGCACGTGCCTGTAGTCCCACCTACTCGGGAGGCTGAAGTGAGAGGA TCACTGGAGCCCAGGAGTTTGAGGCTGCAGTGAGCTATGGTTGTACCAGCCTGGGGGACAGAGCAAGACT CTGTCTATAAAGAAAAAAAAAACAGCTTGGCTGGGTGCAGTAGCTCATCCCTGTAATCCCAGTGCTTTGG GAGGCCAAGGTGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATCATGAAACCCCA TCTCTACTAAAAATACAAAAATTAGCCGGGCATGGTGGCGGGTGCCTGTAATCCCAGCTATTCAAGAGGC TGAGGCAGGAGAATCACTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCCGAGATCGGGCCACCGTACTCC ATCCAGCCTGGGAGACAGAGCGAGACTCCATCTCAAATAAATAAATAAATAAATAAATAAATAAATAAAT GAATAGCCAAAATTTCGAAGGCAGATGAATGCCAATAATGTTCTCAAGAAGCAATAAAACATTGGGTTAT AACCTGTGCCTCTGAGGACTCAAGGGGAAGTCAGGCAGGCCCCAGCCAGCGTTAGTCGCAGCTGCCTGCT CTCCCAGGTCAGCCCTTGCACCCTCGCAGAGGAAGCCGTCCCTTCCGCCTCTCTCCATCATAAAGAAAAC TTCTCTGTCTCTCCATTCACGTCCCAAATGCCTTCTAACTTTAAAATAATTACACAACTATATGTGTTAA TCATGGAAAAGACACTTAAGCAAAAAGCAAGAAAAATCATCCTGATTGTATCCATTGCCTAGAATTTTTT TTTTTTTTTTTTTTTCCCCGAGACAGAGTTTCGCTCCGTGGCCCAGGCTGGAGTGCAGTGGTGCAATCTT GGTTCGCTGCAACCTCCGCCTCCTGGGTTTAAGCAATTCTCCTGCCTCAGCCTCCAGAGTAGCTGGGATT ACAGGTGTGAGCCACTGTGCCCGGCCTATGTTTTTTGTTTTTTTTTGTTGTTGTTTTTCTGAGACAGGTT CTTGCTCTGTCACCCAGGCTGGAGTAAAGTGGCATGATCATGGCTCACTGCAGCCTCAGCCTCCTGGGCT TAAGCAGTCCTCCTACCTCAGCTTCTCAAGTAGCTGGAACTATGGGACCATACCAGCACACCCAGCTAAT TTTTACATTTTTTGTCGAGACGAGGTTTTGCCACGTTGCCCAGTCTGGTCTTGAACGCCTGGGCTCAAGC CGTCTTCCCACCTCGGCCTCCCAAAGCACTGGGATTACAAGCGTGAACCACTGCACCCAGCCTGCTTTTG AGCTGCTTTATTGAGATGTAATTCACATACCATGAGGTCACTCCTCTAAAGTGCACAGTTCAGCGGTTTG AGTACATTCACAGAGCCGCACAGCCATCATCTCTAATTTTGCAGCTTCCAGAGTAGGGCCTCAACGTGGG TTCACGTGATGTTTCCCCAGATAGACTCAGGTCAAACGCTGTTGTTAGAGCCCTGCAGAGCCGCGGGTCT CAGCCCTTGTTGGTATGGCGAGGTCCTGTAGCCGGCAGTCGGCCTCCCAAAATGTTGTTGGCTTTTTCCA GCGGTTGGCAAACTAGACCCACTGCTGGGCTGATGGCCTGTTGTTGTAAATATTTTTTTTTCTTTTTGCC ACCACACCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACTATGTTGGCCAGGCTGGTCTGGA ACTCCCAACCTCAGGTGATCTGCCCGCCTCGGCCTCCCAAAGTACTGGGATTACAGGCTTGTGCCACGGT GCCTGGCCTAGTGCAAATAAAGTTTTATTGGAACACAGCCACGCCCACTGGTAAGGCCAAACCCACGTGG CTTTTGTGCTATAACAACAGAGTTGAATGGCGGTGATCAAGGACTGTATGGGCCTCAAAGTCTAAATTAC TTACCAGCTGGCTGTTCATAGAAACCTTTTCGGATCCCCAGCCTAAGTCATCGCAGGCTGATGGCACAGG TCTGGGCTTCCCAGTCCTTGTGTGGCTGGCTCCTCTCTCCCCGGATTGCCTGTTCCCTGCTTTCCAGAAG CAAGCAGGTGGCCTGGGAAGAAGTGGAACCTGCAGGGTGTCATTCTCCAAGCCGATGCTGAAGATGCAAT GCCTTCACCCGCCTCTTCTGTGCTCTTCATCGCACGGGTGGGCTAGAGCAGGGAAGATGGACTTTCAGGC TGGAGCCTGGCTTTCTGTGGTGGGATGTTCTGTGGGTACCGAGACCCCCTTACTGCATCTTCAGGGACAG AATCTGGCTTGGGTTGAGAGTTTATTTGGCCCTTTCTGATCTGTAATCGGGAGAGATTGATTGAGCTTTC CTGACACAGACGTGGCAAAGCAAACTGGCAGTGGGGCAGGCTTTGCCAAGGCTCGTCATGGTAGCGGAGG CCTGGACAGAGCACCCGCCAACAGCTGCTGCTTAACCAAGGACAGAATGAGGAAATGGACATTTCAGAGA AAAGAGGCGACATGAAAAGTATTGGAGAAAAGAGCCTGGGCTTTGGAGTCAAGTGGGACTGGTTCTGAAT CCCGACTGTGTGCCTCTCTGAGCCTTGGTTTCCTCTTCTGTAAAAGCAAGATCAGACTCTTCAGTGTGGT GCCATGGGAGATTCATATTTTTTTTTTGAGACAGAGTCTCACTCTGTTGTCCAGGCTGGAGTGCAGTGGC ACAATCTTGGCTCACTGCATCCTCTGTCTCCCGGCTTCAAGCAATTCTCCTGCCTCAGCCTCCCCAGTAG CTGGGATTTCAGGCGTGTGCCACCATGCCCAGTTCAATTTTTTTTTTTTTTTTTTTGGTGTGTTTTTAGT AGAGATAGGGTTTCACCATGTTGGCCTGGCTGGTCTTGAACTCCTGACCTCAAGTGATCCACCCGCCATG GCCTCCCAAAGTATTGGGATTATAGGCGTGAGCCACCACACCCTGCCAAGATTAAATTTTTGATGAGTGA GTCAAATGGAGGCCAGGTGGGGTGGCTCATGCCTGTAATCTCAGCACTTTTGGAGGCCAAGGTGGGCGGA TCACTTGAGGTCAGGAATTTGAAACAAGCCTGGCCAACATGGCGAAACCCCATCTCTACTAAAAATATTT TTAAAATTAGCTGGGCATGGTGGCGGGTACCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATC ACTTGAACCCAGGCGGAGGTTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCGTGGGTGACAGAGTG AGACTCTGTCTCAAAAAACAAAAAACAAAAAACAAAAACAACAAAAGCACTGGAGGGGCTCAATAGTTAG TTAGTTTGTCCTAGACCCTTCTAGAATGTTGAGATCCTGGACAGTGCTTCTGAGAAACCTGCAGTCTCTG TCCAAGGAGCCCTTAAGGAAGAAAGGCAGGAGTGTGGGGCAGGAAGACCAGCTTCCCCTTTCCATTCCAC ACGGCTGGCTCGCAATATTCTGTTTCTCCTGCGACAGCCTGGTTCCTCCCTGCTCCCCAGCTCGCCTCTG CCACCATTCTTCCCTCAGTCCAGATCAAGAGTTCAAGGGACGGGGACAGATGATCAGAAAGGCCCAGCTC AGGCAAGGAAGGGGAGAAAAGGGAACTCGTATATGCGGTGGGTGGGAATGGAAAGTAGTACAGTCACTAT GGTGGAGGTTCCTCAAAAAACTACAAATAGAACGGCCATATGATCCAGCAGTCCCACGACTGGGCATTTA TCCAAAGGAAAGGGAATCAGTGCATCAGAGAGACACCTGCACCCCCATGGTCCTGGCAGCACTGTTCACA ATAGCCAAGATATGGAATCAACCTCAGTGTCCAACAACAGATGAATGGCTAAAGAATGAAATAGTATTTC ATTGTGGATGTTGGTACATCTACACAATGAAATACTACTCAGCCATAAAACAGAATGAAATCTTGTCATT TGCAGCAACATGAATGGAACTGGAAGACGTTAAGTGAAATAAGCCAGGAACAGAAAGTTAAACATGGCAT GTTCTCACTCATATGGGAAAGCTAAAAAAAAGAAAAGTTGATCTCATCGAAGTCAAAAGTAGAACAGAGA ATACTAGAGTCTGGGAAGGGTTGGGGGAGGAGAGAGGGAGAGATTTGTTAAAGGATACAAAATTACAGCT AGATAGGAGGAATGAGTTATAGTGTTCCATGTCACTGTTGGATTAATGTAATTAACAATAGGCCAGGCGG TGGCCCACACCTTTAATCCCAACACTTTGGGAGGCCAAGGTGGGCGGATCACCTGAGGCCAGGAGTTTGA GACCAGCCTGGCCAAAATGGTGAAACCTTGTCTCTACTAAAAATATAAAAATTAGCCAGGCCTGGTGGTG TGTACCTGTGATCCCAGTTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGGGAGGTGGAGGTTG CAGCGAGCCGAGATCACGCCACCACACTCTAGCCTGGGCTACAGAGCGAGACTCCGTGTCTCAAAAAAAA AAAAAAGAAAAAGAAATTAACAAAAGTATATTGTATAGTTTCAGATAGCTCGGAGGACATTGAATGTTCC TACCACAAAGAAAGAAATGCTTGAGATGATGGCTGTGCTAATTACCCTGATCTGATCACTATACATTGTA TGTATCTAAACATCACTATATATGCCATAAATATTACAATTATGTGTCCATTAAAAATAAAGGCCCAGCC CAGCTCACATAAGGACGGCAGGTGTGTTCCTTAAAGCATCACACCGGGTCCCAGTACTAGACGGACACTC CGCCTCCGGTTGTGTGACTCTGCCTTTTCTGTGCCCTAGTTCCCTGTTTGCTCCAGCTAGTTGAGAATCC ACACTGCCTGGGTCACAGTGCCCGGCCTGGGTCCCGTAATGTTGTGGGGGGCGGGGGGTGGAATAAGGGA GAAAGCCAGGAGTGCCAGCAAGGCCGGCTACTTGGAGTGTCGGTAGCATGACGCTGCACGTCTAGAGCAT GTACAGAAACCCGATGAGACCCGAGCCTTACGGTGACCCTAGGTACAGAGGACGTTTGTCACCACTGGGT CTCTCTAACACTGGGAAGGTGACATAATCCGTTTGCCCACGGTCACACGGGCAGCTGGGGGTCCAGCTGC ACCATGGCCAGGCCTCTGGCACCAGGTGATGGGGTACGGGGTGCTTCAGTGACACAGCACTTGACGTGAC ATGAGGGAGAAAGGACTGGGTGGGGGGGTCATTCGTGGGCTTCAGGTCCGGGGGGATTATTATGCTCAGA AGGCATGTGCTGACACTGTGGCAGGAGAGCTCTGGGGACAGGTGGGCTCCTTGATTTATCTTTTTTTTTT TTAAAGAGATGAGGGTCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCGTGATCCTAGCTCACTGTAGC TTTAACCACCTGGGCTCAAGCAGTCCTCCCACTTCAGCCTCCCGAGTAGCTGGGATTGCAGGTGTGTGCC ACCACGCTTGGCTAATTTTTAAAATTACTTTTGTGTTTAGAAACCAGATCTTGCTATGTTGCCCAGTCTG GTCTCGAACTCCTGGGTTCAAGTGATCCTCTCATCTCAGCCTCCCAAAGTGCTAAGATTTCAGGCATGAG CCACTGCACCTGACCTACCTACTGTTTTGGGGCAAAGGCTTAGATGGACACGCACACACATGACTCTCCT GGGCTTCTGGTTCAGCACTTTCTCTTCTGGGGGTGCTCCTCTCATTTCATCCTCAATCCTGAGCTGACCC CAGAAGCCAAGGACCAGCCTGCCCAGCCCAGGCAGAAACTGAGTATGCCAAGAGGAATGGGGTCAGGGTG GAGCTGGGATGAGCATTGCTGGCCTGACTCTCCCTTGTGAGGTCTTGTCCACTTGGCCCAGTTGGCTCCA GGGCAGGGAATAAAGGAACAGTCTGTGGTGGTCTTCCCTTCTGTGCACTAGTTCTGGAAAGCAGGGATAA AACAACCAGGCAAATGCATAAAAATACTGTCGAGGGCTTTTCAGCACAAAGGACTTCACATCTTCCTTAT TTACAAAGGCTCTGCGGGGGAGGTGAGGCAGGTGTTTGGATGGGGAGCAGCCGATGACTTGCCCAAGGTC ACCCACAGAGTGGCAGTGCCAGGAATCCAAGGGGAATGATCCTGGCTCGAGTCTCTGGGAAGAAGATTAG ATTTCACAGCTTTGGATTTAACATCACTTTGCTCCTTTTGGCCAAGAGGCATGTTGTCCTCAGAAGGCCT TGGTGACAGGTATATTTTGCCTTAATTTGAGTAGTTTAGAGGCATGGAAGGGCATTTTGGCAGCAGTGAT CAAGGACTTTAAAAATAAGTCTTCCCTTTGATCAGGCAGCCCTATATCTTGGAGTTTTTCTGAGAGAAAT AATTTAGGACACATGGAAGTATTTAGCTGAAGGATATTCATCTCCGTCTTGCTTATCTTACGGAAACGTT AGAAACACCTATATATACAGTAGCAGGGGCGTGGTTAAATAAATCACAGCATCAGATGCTCTGCAGACAT CACATGGTATAGCTTTTTCTTTTCTTTTTTGTTTTTGAGACAGTGTCTCGCTTTGTCACCCAGGCTGGAG TGCAGTGGTGCGATCTCCACTCGCTGCAACCTCTGCTCCCTGGGCTGAAGCAATCCTCCCACCTCAGCCT CCCAAGTAGCTGGGACCACAGACACACACCACTATGCCCAGCTAAGTTTTTGTATTTTTAGTACAGATGG GGTTTCGCCATGTTGTTCAGGCCGGTCTCAAACTCCTGAGCTCAAGTGATCCTCCCACCTCGGCCTCCCA GAGTGCCGGGACTACAGACGTGAGCCACCACACCTGGCCAGAACGTTTGGACACATGAGGGGACATTAGA CTTTCTTTGGCAAGGGTGTATTTTCCAGTTGCTCTAGAATGAACATGAATTCCATGGGTGCACCTGTTTT ACTGGACTTCGCTATATTGTGCTCTGCAGATACTGCGTTTTCATGAATTGAATATCACGGCTGGCTCAAC TCTGAGTCTATCGGTGCCATTTTTTTCTCACATCACGTGTTCACTTCATGTGTTTGTGTCCCATTTTAAT AATTCTTGCAATATTTCAAACTTTTTCATTATTATCATACCTGTTATGGTGATCTGTGATCAGTGGTCTT TGGCGTTACTGTTGTAATTGTTTTGGGGCACCATGAACTGTGCCCACATGAGATGGCAAAGTTAATTGAT CCATGTTGTCTGTGTTCAGACGACTCCACCAACTGGCCGACTGGCGGCTTCTGGTCTCTCTCTCTCTGCC TAGGCCTCCCTCTTTCCTGAGACACAACAATATTGAAATTAGGCCAATTAATTACCCTATAATGGGACTG GGCGTGGGGACTCATGCCTGTAATTCCAGCACTTTGGGAGGCTGAGGCGGGAGGATCACCTTGAGGCCAG GAGTTCGAGACCAGCCTGGGCAACACGACAAGACCCCATCTCCACAAAAAATTAAAGAACTTAGCTGGGT GTGGTGGCACATGCCTGTAGTCCTAGCTACTCAGGAGGCTGAGGCGGGAGGATCACTTGAGCCTGAGAGT TCTAGGCTGCAGTGAGCCGAGATCACACCATTGCATTCAAGCTTGACAGACAGAGCGAGACGTCTCTTAC TTTAAATCAAAAGCTAGGAGTGATTAAGCTTAGTGAGGAAGGCGTGTTGAAAGCCAAGGTAGGCTGACAG CTAGGCCTTTTGTGCCAAACAGCCAAGTTGTGAATGTGAAGGAAATTAAAAAATGCTACTCCAGGTGATC ACACAAATAATAAGAAAGTGGGCCTGCCGGCCAGACACGGTGGCTCACGCCTGTAATCCCAGCACTTTGG GAGGCTGAGGCGGGGGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTAAAACCCCG TCTCTACCAAAAATACAAAAATTAGCCAGGTGTGGTGGCGCAGGCCTGTAATCCCAGCTACTCGGGAGGC TGAGGCACAAGAATCGCGTGAACCCGGGAGATGGAGGTTGCAGTGAGCCGAGATCGCACCACTGTACTCC AGCCTGGGCAACAGAGCGAGACTCTGTCTCAAAAAAAATAATAAAAATAAAAAAGAAAAGGAAAAAAAAG AAATTGCCACAGCCAACCCCAATCTTCAGCAACCACCACCCTGATCAGTCAGCAGCCATCAACATGGAGG CAAGACCCTCCACCAGCAAAAAGACTGGACTCACTAGGTCGAGATGATTGTTAGCATTTTCAAGCAATAA AATATTTTTATTTTTATTTTTATTTCTTCAAGTTTTGGGTTTTTCTTTTTTTTGAGGCAGGACCTTGCTC TGTCACTCAGGCTGGAGTGCAGTGGCATGATCTTAGCTCACTGCAGCCTCGAACTTCTGGGCTTAAGCCA TCCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTGCAGGTACGCACCACTATGCCTGGCTATTTTTAGTT TTTTATAGAGGTAGGATCTCACTGTGTTGCCTGGCTGGTCTGAAACTCCTGGGGTCAAGCCATCTACCTG CCTTGGCTTCCTAAAGTGCTGGGATGACAGGCGTGAGCCACTGCCCCGGCCAATAAAGTATTTGTAAATT AAGGTATGTGCATTGATAAGACATAATGTTATTGCACACTTACTGGGCTACTGTACAATGTAAACATAAC ATTTATATTTGGGAATATATATTGGTTTGGGAAACCAAAAGAGTCATGTGACTCACTTTATTTCAATATT CACTTTATTATGATTCTGTGGGAACTCAACCCGCAGTATGTCTGAGGTCTGCCTGTACCTGTAATTTTTA AAAGCTAGCATTTGCTAATATGTGGTTCTAATTGCAGTCAACAATAGTATGGACCCAGACTCTCAAGGCT GAGTTGGCCTTAGGCCAGTAGTGAATCCCATGCCAGAGAGAACATTTAGCAGGGCGGATTAATCCAGAGG ATGGGGCTGCCTTCTAGAGCTTGCCAAGGCAGCGTCAGGAGAGCCCAGGCTTGAGAGAGATGTCCTCAGT CCAGAAAAGACCTGACGAGCACTTGGCAGTCGTGCTGGACATTCTGCAAGGGCCATCGAAGGCCTAGCGT GCCATCCTGTTGGTCCCCATGCTATTTCCTCCTCACTAGAACCTCTCCCCTTGCTTTAGAATGGGCGTCA AGGCCACGCTGAGAGGATAAAAGATGTAGGGATCTTCTCCGAGGAAGAAGCATATAGAAGATTTTGTATC TATGGGTCCGTATTAGGGTTTCCCAGAGAAACAGAACCAATAGGCTCCATCCAGCTGCGTAAGATGGGAT TTATGTGGGAATTGACTCATGCAAGTATGAAGGCTGGGAGGTCCTGGAATCTGCTGTCTGTGAGCTGGAG CAGCAGGGTCACTGGTGCAGTAATGCAGCCTGAGTCTCAAAGCCTGAGAAGCGGGGTGGCCACTGGGGTA AGTCCTGGAGCCCAAAGGCCTGAGGCCCAGGAGCTCTGAGGTCCAAGGCAGAAAGAAGGTGGATGTCCCA GCTCTCTCTCTTTTTTTTTTTGAGATGGAGTCTCACTTTGTTGCTCAGGTTGGAGTTCAGTGGTGCGATT TCGGCTCACTGCAACCTTCACTTCCCTGGTTCAAGCGATTCTCCTGCCTTAGCCTCCTGAGTAGCTGGGA CTGTAGGTGTGCGCCACCACGCCCGGGTCATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGG CCTGGTCTCAAACTCTTGAGCTCAGGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCG TGAGCCACCGCGCCCAGCCTGGATGTCCCAGCTCTTGCAGAGGGAGGGTTTGCCTGCCTCTGCCTCTGTC TCTTTGTTCTGTCCGGGCTTTCAACAGATTGAGTGATGGTGCCCCACCTGGCGAGGAGGGATCTTCTTAC TCAGTCCCCCGGTTCAGATGCCAGTCTCTTCCCAGAGCCACCCAGAAATCACGTTTTCCCAGCTATCTGA GCATCCCTTAGCCCGTCAAGCTGACATAAAATGAATCATCAAGGGCTGCGAAGATGGACTCCAAAAGTGG GCGGGGGTAGGGGGGTGGTGGTGGACTGTGATCGAGAACATTCCTGCAGGGAGAATGCCTCCCTTCCCTG AGTCAGGGACCAGATAACCTTTCCAGGGTCCTTCCAGCCCAGGACAAAGGGCTTTGTCTCAGGTTCAGCT CTCCTGAGAATTCATCCTCCCCGAGATTTGGACACCTCAGCCGAATTCCTGCTGTTTACCTTCTTCTCTC AAGAAACAACAACCTGAGGATTGTTGCTTTCACTTCTTCGGACCCAAATCATGATTTCCCAGCCACATTT CTCAGTTGTCAAATTTGTGGAGGATGCTGGAAGCTTCTAGTGAGTTGCTTACAGATGATCCAACTGGCGG CTTACTAAAACATATCTTGGGCTGGGGGCGGTGGCTCGTGCCTATAATCCTAGCACTTTGGGAGGTCGAG GCAGGGGAATCGCTTGAGGTCAGGAGTTCAAGACCCGCCTAGCCAACATGGTAAAACCCCGTCTCTGCTA AAACACACACACACACACATAAATTAGCTGGGCATGGTGGCATGCACCTGTAGTCCCAGCTACTCAGAAA GCTGAGGCACTAGAATCCCTGAACCCGGGAGGCAGAGGTTGCAGTGAGCCGAGATTGCGCCACCGTACTC CAGCCTGGGCAACAGAGCAAGACTGTCTAAAAAACAAACAAAAAACATATCTTGACAATGCCAGTCATCA CTTTACCACAGACCTTAAGATGCCAACCACCCAGACTAGGTCAGGGGCCCCCATTTCCAGCAGCTACTCC TGCTTCCTGGAAACCCCCTGCACCGGCCAGACTCCCCCAGTGTCCCATGTTCATCCCCAGCCTCGCCCTG CCAGCTTCCCTCGCCCATCCTTCTGATCAAACTGTCTGTGGGGAACTAGCCCTCAAACGAGGCCAAGTAC GTGTGGCTTCTCCTCCTGTGTGGGCAGGTGGTTGACGGGATTCTTTCTTCCCCCGCCTCCAGTGGGTTTC AGTTTAACGATGGCTTTCTGGAGCTGTTTAGAAGCGTGAACAGATGCTGTCCCTACAGGAGAAGGGATGG CAGGCGTTGTCAGGAACCCTGACCTTGAAGTGTACCTCCTTAATGGCCTGACAGCTCAGAGAGAATGACA CCCTGGGAGGTCTCCATGCAGCCAGCTGGGGACAAAAAGATGTCCTCTGCCTGGTATGGCCACGAGCATT TGTACATTGCACTGTCCTTGTTCACCCACACCTCCTTAAACAGTGCCTTCAGGTGCCCCCATGGCTCCCG GCTGCTTGAGCCAAATCTTTATGATTGATCCCCTAACCTACACGCTTGCCCCCTGGCTGGCTCACAGCTG TCCCTGACCTCACCCCTGCCATGATGTCACAGCTCAACAGCTCTGCTGTTCCCATGGCAACAGCCTGCTA TGAGTAGCCAGCCAGGGCAGAGGCCGGGCTGCAGGTGGAGGCGGGGAAGCGATTCCGGCCACCTTTGGTC AGTGGGCCCCTGAGACCACTGCGGGGCTGAGGCTCTCTGTGTCTGTTCCCATCTGTGGTGAGGGTGGGGT TCTTTCCATGCCCAGCTGTTTAGCGAGGCTCCCAAGAGGGCCCCGGAGAGTGGGCCAAGGAGGGGCTCCA AGCCGTGGGTTCGCAAGGCCAGCGGCAAAGTCCCTGCACCACGGGGCTCCCCACAGGCAGTGTGATGGGA AGGAGAGTGAGGGAAGCTGGTGGGACTGGGTTGGAGATGAATATGGTTGTTGGAGGAGTTGGGCTGGGGG GTCTTCAGGAAGCAGGAACACCTGCTGGGATTGGGGACCCCTGACCTAGGCTGGGTGCTTAGGATCTTGA GGTTTGCAGGGAAGCGGTAATGGACGCTGTCGAGGTATGTTTAGTGAGCCACCGGTTGCATCAGCTGTAA GCCCCCCACGTGGGGAGCTGGCGTCTCAGCTGGGAGTTTGGAGGTCAGTCTGCCTCAGTGTCTGTCTCTG TGAAGCTGGTCAAGGGGAGGCCTGAGCCCGAGCTTGCCCCCAGAGGCTGCCTGCCCAACCATCTCCACCC TGGAGAGCTGACCCAGCCCAGGATATGGATACACACAGATTCATGAGCTGTGGCCCCAGTATTCGGGTGG AAAAGCCTGCTGTGGGCCTAGCCAGGACTCATTCTAACGTGACCCACCCCTGCCCCAGGTGATGCTAACA CAGCCAGTCCAAAACCCAGTGCAGGCTGGGCATGGTGGCTCATGCCTGGAATCCCAGCACTTTGGGAGGC CGAGGCGAGTGGATCACCTGAGGTCAGGAGTTTGTAACCAGTCTGACCAATATGGTGAATCCCCGTCTCT ACTAAAAATACAAAAATTAGCTGGGTGTGGTGGCGTGCGCCTGTAGTCCCAGCTACTTGGGAAGGCTGAG ACAGGAGAATTGCTTGAACCCGGAAGGTGGAGGTTGCAGTAAGCTGAGATCGCACCACTGCACTCCAGCC TGGGCAACATAGTGAAACCAAAACCCAGTGCAGTGGCTTGGGACCCCCGTCCCCCCGCCACCACTGGGAC GTGGCTAAGAGTTGGGGAGAAGAGGGCGAAAACCAAGCCTCTGGCAGCACACAGCGTGTCATGGAGGGTA TTTTTAGAGGCTAGAACTCAGAGAAACGGAGTTAAAAATGTTTCTGATGTTTGTTTTATCTGGGCTTGGT TCGGATGCCTCCAGTGATGGGCGTCTCACTACCTACAAAGTCAGCCCAGTGATTTCAAGACAGCCCTGGA GACAGTGCTTCCTGCCCTCCTGTCAGCTTCTGCCTCCCTGTAATGTGTTCTGGGTGGTCTAGCTCAGTCA TCTGGAGACACACACAGTAAGTACCACCCCTCTTCCCCAAGCATTTCAGGTGCTTCTCGTGGTGACAAGC ACTGGCATCTCTGTAGATGGGTGCTGCTGTTGTTATCATCCCCATCCTAAAGAGCAAACTGAGGCACCCA GAGTGAAGTCGCTTGGCCTAGGTCACATAGTACTCTTAAGCACCATACTCTGCCATTCTAGACTTTTCTA TCCTTTGCAAACACCCTTGCCCCACCTCACCTCCTTTGGCTTTTCTTCCTAGGACCTTTGGTCAGTGGGC CCCTCCTGACCAAAGGAGTTCATTCTCCTCCTGGACTCCAAGCCTGCGGCCTCTTCTCCCCGTCCTTACC GCCCTCCTCCTCTCCCGAGAACTGTCCAGGAAGACACACCTCTCCCTCGTTCAGATTTGCTCCTTGTTCT TCAGCCCGTGCATCTCCTTTAGGTCTTGAACAGTTCTGGACAGGTTTATTCCTGATCATTTCATCACGGT TTTATTGATTTTGAAACTTTATCCCGTGACATGATCAAATTGGCCATTTCTAGAGCACAGGCACTTCGTA GCTGTTGACCATCATTTAGCTCCACGTCTGCCCGTCGGTTCCTCGTGCGTGGAATCCAGCACCACGTGGG TGTCTCTGCCGAGCTCTCGGCATTTCCTGAGCCCTCCCGGAAGCCAGACTCTGTTCTCGGCGCTTCACAC GGGCCGTCTCGTCTGATGCTGTGGCGTCCTGCAGGGTGGGAACGGGCGGTGCCCGTGGACGTGGCGCTGT GCCTGCCGGCGTCCTGGGCACCACAGCGTTGCCGCTTGCCCACTGCCTCCTAGCATGGCCAGGTGAGGTC GGGCTGGCTGGGCTGCACCATTCGCTCGCATGTTAGAGGCGTTTCTGTTCACTCAGGGGACAGTCACGTT GGCCCTTCTGGTGGCCCAGCGTCTTTTGTCCCCTGTGCTGCTCCACACACCCACCTCTGTACTTGCATAG TTGGATTTAGGGACCCACATATAAGTTTTAGATGTGTTCCCATTACCTTTTTTTATCTTGTAAGATTTGG CCAGTTGTGCAAGCTGTTAAAAACCTCTAGGCTAGAGTCTAGCAACAATTTTCCACCTCCCCCAAGGGTT ATCTGTATCCGGGGATGCCCACAGCTTTGAATTGATAAGGTCAGGTGTGAAAGCTCAGGCAGTGGTCCTG TGGAAGAGCCCACCACCACCTCGGACTCTACTTACTTTATTAAAAAACACATTTTTTTTTTTTTTTGAAA TGGAGTCTTGCTCTGTTGCCTAGGCTAGAGTACAGTGGTGCGATCTTGGCTCACTGCAACCTCCGCCTCC TGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATATACCACCACACCTG GCTAATTTTTTGTATTTAGTAGAGACGAGGTTTCACCACGTTGGTCAGGCTGGTCTCGAACTCCTGTCGT GAGGTGATCCAGCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCAAA AAAACCACAATTTTAATAAGCTTGTTTGTGTGGCTGCTGTCAGACAGTTATGACCAGGGAAGGGAGGACA CAGGAAGCTCTAAAAAGGCGACTTAAAAAACCCAAATTGCATTCTGGGGTCACTTAGTTTATGGGACCTC TGTTCTTTACATTTTAAAAGCCCTCGAGGGATTTCCTATATTATCATCCCAAAGACAATCCAAAATTTCC CCCAAAGAAGGTCAAATTACATATTCTACGTAGGCGCCTTAGACAGAGAAATGTCTAACTTTCCATATGA AAGGGTAAGCTCTAATTATATGGAAATGTTCTCTCTCTGGCCGATGCCAGCTAACGGAGCCCTTCTATAG CTATTTTTATGTTTCAAAGACAAAGCGCTTGACTATGTGGCCCGGGTGCTGGGCTTCTGGAGAAAGGGAA GAGCATTCTCTTTGTTCCCTTGGAGGGTTGGGGCATCCTGGGGGAGTGGGAACGAGGCCTGGGCTGGGGA CATGCGGGTAGGATGGGGAAGGGGGTGTGTCCATGTCACGAGGAACCTGCATGAGCACATTCCAGGCGCT GCTGGGTGTGGGGCATTTGGGAATGGCCAGGAGCTCTACCACCCCTGTCTGGTGTGCAGCGTTCCAGGCT AGGGTGGCTCCCAGGGGAGCCAGGGCGAGCTGCTTGACCGTTCTCAAGCCTCTAGGCCCAGAGATTGCCA GGCTTTGGCAGGGCAGCTGGTGAACTGGCTGCATTCCTGGGCCCCTCCCGCAGGGGCTGGGATAGGATCT GTCAGGGGTGAGGCCCAGGAATCTACCCCTTCACCAGCAGCTCAGCTGATTATGATGCACGTGGCTGCGG GTTGCACTCAGAGACTTGCTGGTGTGGACAGCAGGGAATCACATGGGGGATGCTGAAATGTAACCCAGGT CTCTCAGTTAGACAGCGCTGGGCTGCAGTGCGGGAGAGGACGGGGTGCAGGCCTGGGGGTCGGGGGCAGA GAGGCTGATTGGGAGGCTTTTAAGGGCCTCAGGTGAGAGATGATCAGGGCTGAGCTGCTGGCAGGGGAGG AAGGCAGAGCAAGATGCAGCTTCCTGGAAGAGATGGTTTGCCAGGGCCGCAGTACTCCAAGCGTGGTCCC CCAGATGGCAGCATCAGCATCCCTGGGAGCGCTTTAGAGATGCAGAGTCTGGCGGGCGTGGGGGCTCACA CCCGGAATCCCAGCACTTTAGAGATGCAGAGTCTGGCGGGTGCGGGGGCTCATGCCTGGAATCCCAGCAC TTTGGGAGGCCAAGGCGGGCAGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCGGCATGGTGAAA CCCTATCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCGCGTGCCTATAGTCCCAGCTACTTGG GAGGCTGAGGCAAGAGAATTGCATGAACCCAGGAGGGGGAGGTTGCAGTGAGCTGAGATTGCACCACTGC ACTCCAGCCTGGGCAACAGAGCAAGACTCCGTCTCAAAAAAGAAAAAAGAAAAGAAAAAGAAATGCAGAG TCTTGGGCCCCACCCAGACTATTGAATCAGAGCCTAACTGTTAACAAGATTCAAGCAGCACCATGGCCAG GTCTCACCCTTCTGTGCATGTTGACAAATCAAGTACTTGAGCAGAAAGAAGATGGGGATGATCGACGTGA TGAACTCAGAGGCACCAACCGTGGTGTCCTGGGTCGATGCACACAGAATGCACGCAGGCCCCTTGCAGGC CTTCCCACCCTTCAGAAGCTCAGCACACCTGTCAGGGTCACAGGAGGGCCAGGGAGGTCAGAGGTCACGT GAGGCCAAGCACAGTCCAAGCAGAGTCTCCTTGTGCTGTGGAAGTGGTTTCCAGCTCTGACCTCCCTGGG CAGCAGGCTAGGAGCCTGGATCAGGGGCCTGCCTGCTCGGCCCGGAATCCCTGCTGCCCTGATTACGAGC TATGTGGCCTTAGGCAAGTTACTTAACCTCTCTGAGTCTCAATTTCCCTGTCAGATTGTGCGGATAGGAA TAGGCCTCACCTCCTATGGTGAGGCGGTGAGATGGAGAGAGGTGTACGTGAAATGCCGGAAGAGTATGAA ACCCTGCGGGTCTGCGTGCTGATCAGTGTGATGTCTGGATTCAAACCCAGCTCCTCCGTGTAAGCTGGGA AAGTTATTCAGCCTCTCTGAGCTTTTGTTTCTTTTTGTGAGCTCAGAGGGGAAATCAAGGAGAGCTGGAG GCGGCAGGGACAAGGTTGCATCCGATGGTGTCATGGGGGAAATCAATTCCTGAATGATGGAGCCAGCTGT GATTTTCTGGACTTTATCCCAAAGACCTCTGCCCAGATGTTTTAAGTTTGTACCCATTTCCGTGTCTCCA GGAAAACCGACACAGCAGCCCCGCTGGCTCCTTTCACAGTCACCCTCTGGATCATGTTGCAGTGACTCTA GCCAAGGGTATGGCCTGTGTCGTGTCTGTTACAGGCCGAGGTGGGAAGAAAAGGTTGTCCCTGTATCTGG AGGGGCCAGTTCATGCCTTGAGGAGGAGAGAGGCACTCTGGGTCCTGCCATTGTCCTCAGGGATGGCCAT GCTTGCCATTGTCCCACGTGTCTGTTCGGGGGGGTCCTTCTCCTGGGGATACAACGTCTGCCGCGTTGAT TTTTGGGTGTCTAAGTGTACCGGGCTAGTATCACATTGAGAGTCACCCACTGTGGGTGGATTCACCCATT CCCGTCATGGTGCCTGGGGCTCCAGCAGCCTCGTCACAACACAGCCTGGTAGTTGGAGGGTCTGAGCCTT TGTTACAACCGCCCTGACTTAGCCGCAGGACTATGCACCTGGTGGGGACTGGGGTGGGCGGCCACTCTCT CACAGGCCCACCCCAAGGCTCTAGATGGGCACGTGCATTGTTCAAATGCCGTCATACCTTGGGGGTGCGA GGGGGCAGCGTGAGGCAGACGAGAGAGGCGGAGGTCTCACAGTGAACCACAGGATCTGGTATCCTGCAGC CGGGGTGCAGGCCTGACTGTGGAGCCCCCATTCTGGGCGCCTCACACTCCCTATGACTGTGATGCTTGCC CCCCGCCCCCCGATGCCACAGGAGTGCACAGCAGGCCTGGAGTCTCCTTCGGAGGGGGTGAGGAGGCCGG CGGGGGGCGGGGGGGTGCTGTCTGTGGGCCCTGGCACTTCCACGCTGCCTGGGTGGAGGGTCCCTGGGTG AGGTCTGCCTTGGCTGAAAAGCTGTCTGAGCGGCCGCCCAGGGAAAGGCGAGCTGCTTGGACGTCATTCT CAAGCTGTAGGCCAGAGGTTGCCTGACTTTGGTGAGAATCGCTGGGAATCTGGTGGCCAAGCACATTCCT GGGCCCAGGTGCTGGGATCGGATCGGTCTGGGGTGGAGCTGCCATGGGCTGGCTCCTGCGCTGGGGCCAC GGGGCTGTAGAGAGCAAGAGAGGAGAATGGGCCCAGTGTCCACTCCGCTCTGTGGGAGGCCCTGGTGCCG TCCGGAGGCCAGATTGGTGTCCACTCGCCTTCCTTCTGCTGCTCCGAGCGCGGCTTCTGCGGAGGGGGGA GCTGTGGTTTCTCTGAGTGGTTGAAGGCAGCCAGCAGAAGGCAGGCTTGTCAGCTCGGGGTGGCAGGACC AGAGGGCAGCAGGGGAGTAGAAAACACCAAAGCAGCCCAGGATGCTCAGAACACTCAGAGGATGTGGAGG ACAGAGGAGCGCCAGGACCCCTGCCCCTTCTAGAATATTCTAAGCAACCAGAGAGGGCAGGTGCCTCTGG GAGGGGAGCTGTAGCGAGGGCCCTGATTGGAACCATGGCTGTCTTCATTGGCAAGTGTCCTGCCAAGGGC ACCCGACGTCCTGTCTGGCAGGGCTGGAGAGACACTGGGCTGCCTGGAGATCAGCCTGGGCATCACAGGC AGAGGCAGGCATCCCAGCAGGCTGTGCAACAGGTGAACGGCTGTTTCTCCTTGGTCATCTTGGGCTCAGC TAAGGCTCTGTTGCTTTCCCTGCCAGTGCCTGCACAAGTCCACGTGAGACCCTGCCCTCTGCCTCAAGTT AGTAAGTGGGGAGGGTCTCAGAGGGGAGAGCAAGGAGAGCTGGGGTAGCGGGGACGAGGTTGCATCTGAT GGTGTCAGAGCGGGGATCGATTCCTGAAGGATGGAGCTGGCTGCAATTTTCTAGACTTATCCCAAAGATC TCTGCCCAAATGTGTTAAGTTTTTACCCGTTTGCGTGTCTCCAGGAAAACTGACGCTGCTTCATTGGGAT GCCCACGCCAGTGGGGCTGGCACGGGGTGCACTGAGGTCATTGAACGGGCTGGGGGCACTTCCAGAGCAG GGAAGACTTGTCCAGGTTTTACTAATTGTTGGTTGACAAGGGGTGTGAGCCAACGGCTCTTGGCACAGAA ATAGACTGTGAACCTTGGGGCCTCCAGGCACCTTCCGAGACACACAGAGGGGCATTCACAGCAGCCCCGA CCTCACCACACCTAATTGGACATCCCTGTGGCCGTTCCTGGTGGTCTTTGGTGTCTGAGGCCAACTCCTC CATGTGAGCTGGGAAAGTTATTCAACCTCTCTGAGCTTTGGTTTCTTTTTGTGGACTCAGGCCTTCTCTT GGTTATAGACCTAGGAGTGGAATCTCTGGGTCATAGGGTAAGTCTGTGTTTCCCTTTTTAAGAAACTGCC AGACTGTTTTCCAAAGTGGCTGCACCATTTTCCATTCCCACCAGCAGCGTGCACAGGGTTCCAATTCCTC CCCCTCCTTCCTCACTGACAGTTGCTATTGTCTGTCTTTTTGACGACAGCCGTTGGAGTGGATGTGAGGT GGCAGGACACTGCAGGGTCAGTGTGCATTTCTCTAAAGACCGCTGCCGTTGAACATGTTTTTATGTGCTG TATTAGCCACACATCTATGTTCTTTGGTGAAATATCTATTTAAATCTGTTGCTGATTTTTATTTTTATTT ATTTATTTTTGAGACAGAATCTCACTCTGTCATCCAGGCTGGAGTGCAATGGTGCAATCTCAGCTCATTG CAACCTCTGCCTCCCAGATACAAGCAATTCTCCTGCCTTAGCTTCCCGAGTAGCTGGGATTATAGGTGCG TACCACCACACCCGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGTTAGGCTGCTT TCGAACTCCTGACCTCAAGTGATCCGCCCGCCTCAGCCTCCCAGTGTGCTGGGATTACAGGTGTGAGCTG CCACACCTGTCCTTCTTTTGCTGATTTTCAAATGGGATTATTTGCCATCTTACTGGGTAGTAAGAGGTGT TCATATGTTCTGGATTCAAGTCTTCTGTTGGATATATGATTTGCAAATATTTCCTTCCAGTCCGTACCTT GTATTTTCACTTTACTTATGGTACCTTTTGAAGCACAAAGGTTTTTTTTTTCTTTTAATTTTGATGATGT TCAGCTTATCCGTTTCTTTGTTTATTGGTTGTGCTTTTGGTGTTGTATCTAAGAAATCTTTGCCTGACTC AAGGTCATGAATATACACCTACGTTTTCTTCTAAGCGTTTATAGTTGTAGATGAAGGTCTATGATCCATT GTGAGTTAATTTTTGTATATAGGGTGAGATAAGGCTGTGAATTCCCATTTTTTGCCTGTGGATATCCAAC TGTGCCAGCATCATTTGTTGAAAAACAAAAAAACTATTCTTTCCCCACATTAAATTGCCGTGGCACCTTT GTCAAAAATCTCAATCATTGCATTGAAGGGCCCAGCTTTCTCTCTCCCTTTCTCTCTTGATCATCATGGT GGTTGGCAGATCTGGCTAAATATAATATTAACCACTATTCTAATTGTGTGATCTGATTTACCAAGAGGTG CAAGGACCTCCCACTAGAAGACTTAAGTCAAAGCCAGCTGCAGTGTGACCACCTGAGGTTGGTCAAAGGT GCTGGGGTTCGTCCAAGCAGCAGAGGGCCTGTCTCTGCCACTTACCAGCTGTGTGATCTGGGTTAAGCAT CTTCATCTCTGCCTGCCTCAGTTTCCCTGTCTGTGAACCGGGGGGGGTAGGAGCTTCGTATCTCAAAGGA TTACTGTAAAAAAGATGAACGGATACATGCCCAGTGCTCAGAGGGGAGCCTGCACGGTTAATGTTAGCTG TAATGTAGATGCAGTATTTTCTGACTCCTGCAACTACATGTGACTTCAGCTGCAACTACGTTTGACTCCA AAGGCTTAGCCTGGTTCCACATAGACTAAGATGAAAGAAGGGAAGGAGCAGTGGAGGGGGACTCCATATC GACTGTGGCTGTCCCTTAGCCTTTCCTGCAGCTCACAGATCTGGCTGTTTCTGGCATCAGCTACCCGTGG CAACAGACACAATCCCGTACTGTTTTGGTGTAAATGCCCCTCCTTTCCTAGGAAGGCCTGCCAAAGCATG GGTCCCTTCCTGATGCCAAAGAGACCTGGAAGAGTCCTTCTCTGATCATTATAAAAGGAAAGAGCTGGGA GTCATGAAGAGAGAGCTAACACCAGCTTCTCCTCCTCTCTGGTTTCTACTGGATTCAAGTATCAGACTTG CATGCACACATACATACCTGCATGCCCCACACGGACACATACACATACACACACCGACATGCACACAGAG GCACACACAGACATGCATACATACACACACCTGTACACCCCCCTGTACACACAGATGTGCAGGCATGTGC ACAGAAACATAAACAGATGTGCACACGCACACACCCCTGCGCGCACACACCCCTGCACACACACCGCTAT GCACACACACCCCTGCACACACAGCCCCACGCACACACCCCTGCACACACACCCCTATGCACACACACCC CTGCATACACACCCCTGCACACACACTCCTACACACCCCTGCACACACACCCCTGCACACACATGCATGG AGACACACACACCCTTGCACATACACCCCTGCACACACACCCTTGCCCGCACACCCCTACACACACACCC CTGCACACACACTCCTACACACACATGCACACACACCCCTGCACACACATGCACACACATCCTTGCACAC ACCCCTGCACACACATGTATGCACACACACCCCTGCACACACATGTACGCACACACACCCCTGCACACAC ATGTGCATGTGCACACACCCACACACACCCCTGCACACGCGTGCACACACTCCTGCACACACACATGCTT GGCAGGCTCCTCCCTGCCCCGTCTCTTCCTCCTTTCCTTTACGATCAATTCTCCCTCCAGAGGCCCAGAC TTCCTCTTTTACTTCCACCTGCTCTTCTCAATATTTGTTTCCAAGGGCTGCCCTTTGTGCCCCTCCATCC CTACCTGAATCCTAACCCTTGCCCTTTGGGTGGGATTGTCAGTCTCGGCACTACTGACATCTCTGGCCAG GTTATTCACTGTCTTGGGCAGCCCTCCTGTGCAGTGTGGGGTATTCAGCAGCCTCCCTCGCCTCCACCCA GCTGCAGGCCCGGAGCACCTCCTCCCTGCATTTGTGACAATAGAAAATGTTTCCAGACATTGCCAATGTC CCCTGGGAAACAACACCACACTCTGTTCAAAACAGCTGCCCTACAGGCTCTTGTCAAAAGTGTACAGGAC AGAAATTGGGAGGCTGAGAGTGGGCCCTGGTGGGCACGGGTCAAGAGAGCTTGGAGGGGCACATTTTGCA GCCTGTCCTCACAGTGAGAATCCCGTGTGCTTGTCTCCAGGGCTTTGCTCACTCTCCTGGGAGCGATCTG GAAAGCTGCACTTGTGCTCCCTTCCTCGTAGGTTTGCTGTGGAACGTTGTGGCTTCTGTGGCTCCTCAGG CCCGGGGGCGCCCCTTGAACCCTCCACTCTTGGCTCCAAGCACCTTCCCTGGGAAGCTGTATCTGCTGGG TTCGCAGACAGGAACAGAAACATGGATGGAGCCATGTGGCTGAGCCTCTGTCCTGATAACGAAGACCTGC TTTGGAGGAAAAAGCACAAATTGCTACAAGCCCGGGGCAAAGGCGATCTCGCTCTGCAGAGAAGAGCGGA TGCCAAGCTGTGGAAAAACTACCAGCTCCAGCGCTTGGCTGAGGAGTTGAGGAGAGGGTATCAGGAGGCA CAGCACCTGCACGTCGGTGGCCTGGACAGGCTGCAGTCAGCACGTCTGTTGGGCTGGGGAGGAGGACGGG CCAGGGAAAATGAGCCTGACTCGCAGGGGCCCATCCAGCGAAGATCAGCCAGGCCCCCGAGGGCCAAGGA GAAGCATAGAGCAGCCCTTAGTGAAGAGAGGAGTTGCAGGGAAGAGTTGGGCCAGCAACACCCCAGGCAC TCCAGGCCCCGGAAGACAGCAGCGAGTCCAGAGAAACCACAGACTACAAAAGCCACGGGTCGGATGAATT CTCACCTGGCCCCGCCTGAGAAGAGAAAGGGAAGGCCAGAACCTTCGACCAAGTCTGGGGGTGGCCGCTG TGCCATCCATCCTCGGAGGAGCAAAGGGGCGGACCTAGAAAGGTCAAACCCACTCGTGGCTGCTGTGGGA GAAATCGGGCTTGTGGAGGAAAAAGAGAAAGGAACAGCTCGGGCGGGGAGGAGGCAACTGGGAAAGGGGG CAGTTTGCTTTGTTCCAGCCCTGACCAGTCGCTCTCAGGGACAGAGTCTGGAGGGGAAGCTGAGAGACCT CGGGCAGCTGTGGCCAGCTGATTCCAGCTGCAGAAGGGAAGCCGTGTCCCCAGCATCTCAGTGCACGCTC CGGGAGAAGAACAAGTGGCAGAAAGAGCTGGAGTTGGCCTTTGAAGAGTTGTTTAATATAAACAGAAAGC TGAAAAAACACCTGTGCTTGTACCTGGCACTGAAGCCCAGGATGGACCAGAGACCTGGGGAAGGGCATGC CTTCTCAGAGATGCAAGAGTGTGGCGCTGGGACCCCAAGAGGGAAGAAAATGGCAGACCCAGAGATGCTG CCTGCCGGGGAACCCAGGAGCCCAGCAGAGGAGGAGGCGCAGCAGGCAGCGTCCAAGACCGACTTGAAAA CGTTCATGGGCAAGGCCCAGAACCAAAAATATCAGGGCACGGTCAAGCCCACGTTTAGAAATGGAAGTCA AACATTGTCTCCCGAGGCAGGTATATTTATCAACAAAGAGGACTCATTATTGTATAGCACTGAATCTGGA CAAGAGACCCCCAAACTGGGCACGCTGGCAGAGGGCTCCCTTCAGCTCCACCTTCAAGACCAGGCAGACA GAGTGGGCTCGACGGCATCCAGGCAAAGGCAGAAAGCAGAGATGGAGCAGAGAAGACAAAAACAACTGGA ATCGCTTGAACAAATGGAACACCCAGATATGAGCTTGGAAATCCACTACAAAGCTGAGCTAGAAAAAGAG AGGAGGGAGCAAAGAAGAGCTCGACTGGCCCATCTGAAGTCCTCCTCCACGAGAGCCCAGGAAAGGGAGA GAGGATCTGAGCTCAGCACCACTTCCCCATCGGGCACCAGCCTCGCCGACGACGACCGGCACAGTCAGAT GATCCGAGACCAGCAGCAGCAGATCTTACAGCAAAACAGGTTGCACAAGCAGTTTCTTGAAGAAGCCCGG AAATGCTTGCGGGAGTTTCAGAACATATGCTAAATGCGAGAGGCCCACCCGGGGTAAATACATCACTGAT AATGGTGCTGCCAGCACTGGTACCCGGGTCTCTAAGATCTGTGTTTGCGTCATTGCCTCAGAGACTATTA GGCCTCTTTAAAATGGGCAATCTGGGGCCGGGTGCAGTGGCGCACGCCTGTAATCCCAGCACTTTGGGAG GCCGAGGTCGGCCTCAGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGCGAAACCCC GTTTTTACTAAAAATATAAAAATTAGCTGGGTGTGATGGCATGTGCCTGTAACCTCAGCTACTCAGGAAA TTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAGGTTGCAGTGAGTCGAGATTGCACCACTGTACTC CAGCCTGGGTGACAGAGTGAGACTCGTCTCAAAAAAAAAAAAAAAAAGCAATCTGTCATTATACCGTCCT CCAGGGCACATTCCCTCACAGGGACTCTTTCCCTAATCTTGCCTTTATTGATTGATTGATTGATTGAGAC GGAGTCTTGCTCTGTTGCCCAGGCTAGAGTGCAGTGGTGCAGTCTCGACTCAGTACCTCTGTCTCCTGGG CTTAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTATAGGCGCCTGCCACCATGCCTGGCTA ATTTTTTGTATTTTTAATAGACACAGGGTTTCACCATGTTGGCTAGGCTGGTCTTGAACTCCTGATCTCG TGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGACTTGAGCCACCGCGCCTGGCCTAGTCTT GCCTTTAAAACGAAGTCCCTTTTGGGAAACCACCTATATACAAAAATAGGAACCCGTGTGGGTTTCAGTG GGTGTGTCTAGCCCATGTGCTGTGGATGCATCTCCCAGAGCCGATCATGTCACTACATTCCAGCCTGGGT GACAGTCTGTTTTCAGGGGCCACAGGCACAGATGGAGACTCCAGGTCATTTAAGCCCTTCAGATGTTTTA GCCAAATAAACACTGGCCTTTCAGGGGCACCCAAGGTCAGACGGGCACAATTTCAGGAGATAGATCACTT AGTGCTTAGCCAAGGCTGAGACATTAACGGAGATTGAACCAAAGCTAAAACCTCTTAGTCTTTCAAAGTC ACAACAAAACCAACATTGTTTAAATAGCACGTCGCTTAATACATTCTTATAACTTTAAGAGAAAAGAGAG TAGACGGAAAAGAGAAGACAAGCCACCCTCGCCCCGCTGGGTGATTCCCTCTGGGGCTGGCAAGGGTGTC GGCACCTGGGTGTTTGATCAGTTTCCTCCCCGCTAGCTTTGCCACTGACCTGGCATCCACCAGAGCCATG GAGACCTCACACTGGGTAGCTTCTCTTCTGCCAATTGCAGTCTTAGGGACAGGCACAGGGATCAACATAC TTTTTCTGCAAAGAGCCAGAGAGTAAATATTTTAGCCTTTGCCAGCTGTGCAGCCCCCGTGGTAATTACC CAGCTCTACTGCAGCTGCTCAGAAGCAGCCACAGATGAGATGTAAATGAAAGGGCGTGGCCAGGTTCCAA TGAGACTCTACAAAAATAGGTGGTGAGCGGCATCTGCCCTTTGTGCCATAGTTTGCTGATCCCTGTACTA GGATGGTTTCAGAGTCTGTCTCTCTCCCTCCCTTCCAACAACCTCAGATACATTGACTTAGATCAACCAA TCTTTGTTCATGACACATTAGTATCATTGGTCCACGAATGGCCTTACTTATGTATATTTTGTAGACAATA TAATGAAGTACCATGAGCCCATCACCCAGACCCAAGACCCAGAATATTCACTACCTGTGCGCTACCTCCC TTTTCCATCCCCCTGCTGCCTCCTTGGACATATACCTGCTGATGGCTCACACCTACAATCCCAACATTTT GGGAAGCCAGCGCAGGAGGATCACTTGAGCCCAGGAATTCGAGACCAGCGTGGGCAACATGGGGAGACCC TATCCTACAAAAAATAAAAAATTAGCTGAGCATAGCGGCCTGCACCTACAGTCCCAGCTACTCGTGAGGC TGAGGCAAGAGGTTCATTTGAGCCCCAGAGACTGAGGCCGCACAGGGAGCTGTGATCACGCCACTGCCAG CCTGGGTGACAGAGCGAGACCCTGTCTCAGAAACAAAAAGATACTGGACGCGGTGGCTCACACCTGTAAT CCCAGCACGTTGGGAGGCCAAGGCGGGCGGATTGCTTGAGGTCAGGAGTTTGAGAACAGCCTGGTCAACA CTGTGAAACGCTGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGTGGCATCTGTAATCCCAG CTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAATCCGGGAGGTGGAGGTTGCAGTGAGCCAAGATTGC GCCACTGCACTCCAGCCTGGGTGTCAGAGCGAGACTCCATCTCAAAAAAGGAAAAAAAAAAAAAAGAAAC AAAAAGATATATACCTGCTGAACTTGGGGTTTAGCCCTCCCTATCTTTATCCATATATGTATGCTAAACA TAGTGTTTAGTTTTACTTGGTTTTGAACTTTATAAAAAGGATATTATGTGGAGTCTTTTGAAAGCTAGGT TTTTTGGCCTCGGCACGGTTACTGAATTCATCCACATCACACAAACGCCTCTTACTCATTTTCACTGCAG CATATCCTCATCGCGTGTATGAGCTTCTTTCCAGGATCATAGCTTCTCCAGTTTCGTGCTTGTTTCCAAA AAGAGGACTATATCTCTGATGCATTTGAATCAAAGGACCGGGTGTCAAAAAGTGCTTTTGGCACAGCTGG GATGTAGGTGTGGGAAAGATCCCGTTTATTGCTCTTTTTTTTTTTTTCCTATTTTTTTTTTTTTCCCCAG AAAAAGATTGACCTGCTCTTATAAAATATTTAATTTACAAATATGAGGCTGGGCGCGTTTGCTCATACCT GTAATCCCAGCACTGTGAGAGGCCGAGGCAGGTGGATCACTTGAGGTCATGAGTTCGAGGCCAGCCTGGC CAACAGGGTGAAACCCCGTCTCTACTAAAAATACGGAAATTAGCCGGGCGTGGCGGCGCGCACTTGTAGT CCCAGCTATTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGGTTGCAGTGAGCTGAG ATCATGCCACTGCACTCCAGCCTGGGGACAGAGGGAGACTCCATCTCAAAATAAATAAATAAATTTACAG ATATGAGTCCTAGACACTGTCCCAGTCACTAGAGATGAGCAGTGAGCCACACACATGGAACCACAGGACT CCCGTTCTGGTGGAGGACGCAGATGATGAGTGAGTAAAAGCTGGAACTATGGCTGTGCAGGACAAGGTGC TCAGTGGGACCCCAAGTGCACGCCTCTGAGAAACTCAAGCCGGACTTCCCTGGCGAATGCGAAGCTCGTG GAACCAACAAGCGTTACGCTCATTTGGACGGGGCGGGAGTAGCATCCCACAAGACTCTTTTGTTTTTGCT TTTGGGTTCTTTAATCATTAGTAGCTTAGGTCTCTGTTGTCTGTGGCTTTCTGCTTCAGGCCAAGTAGAG GAAATTCGAGGCTGGGCATGGTGGCTCACACCTGTAATCCCAGCACTCTGGGAGGCCAAAGCAGGTGGAT GGCTTGAGCCCAGGAATATGAGACCAGCCTGGGCAACATAGTGAGATTGTGTCTCTATAAAAACAAAAAG TAGCCAGGCATACTGGCGTGCACCTATAGTTCCAGCTACTAGGGAGGCTGAGGTGGGATGATCTCTTGAA CCTGGGAGGTCGAGGCTGCAGTGAGCTGTGATTGCGCCGCTGCACTCCAGCTTCAGTGACAGAGACCCTG TCTTAGGGGGAAAAAAAAAGAAGAAGAAAATTTTGATCTTAGCCTGGTTTCTTTCTATCCTCTGCTTCCA GAATGTCATGGGCTAGGGTTGCAAAGCCACTCCACAATTTGCTATAGGCTCAACATGATTAAGAAGGAAA CTGGGGGTCAGGAGGGCTGCTGTTTTTCAAAAGCCACATAGATTTCTCGGGGTGGGGTGTCACCGTGCTC CTGCTGTTTCTGCACTTGCCTTGTGCCCAGCTATTTTTTGCACACGGAGACCTGGAGCGTAGCCGCCTGT CAGTGTAGCATCACCTCTGTCTGAGAGGGCAGAGAGGGTGTTATGGCATGACTGAGTTAAAAGCCATGGC CACAATGGGGCCCAAACATTGAGTAGCCGAGGTCTTCCTGCCTTAGCCTGGAAGCCACAGTCTGATGGGG GAACCAGCCTGCCTTTGAGTGGGTTATTTTTGTTTCCATTTTCAAAGGTAGCATTTGTGACCCATGTGTT CTAGGTGAGGAATCGCCCCTTCTTGACCACACGAGCTAAAACTAGGCGTGGAGACGGGCAGCAAGACAGT GTGGAGGGTGACTCATCTCTGCCCGGACGGTCACACCTGCACTGTCCCCTGGCAGCAGGACCAGACACCC GGCCCTTTCCCACCTGTCCTGCAGAAGGCTAAGGGGACAGGGTGGTTCTTTAACTAGGGCATTGGTGTGG GCACTAAAACAGCCCTCCAGGATGTCCACACCCAAAACCATGGCCCTCCAGTGATTCTTACGGAGATGTC ATGAGTAACTTTCCATCCCAGGGCCTGGCAGTGCCTGTGTTCCCCTCCCCCCTTGGTCACCTTGGCACAG CTGGACTGCGGTAGAAAGGGCTGTGGAGCAGCCTCCAGCTTCCCCTGGCTCACCCCGTCCCATGCCTCCA CCCAGAGCCTCCACCAGGAGCTGGTGAGAGCCCTACTGCCGGGGTTGGAGCCCTGGCTCTGCCATTTGCC AGCAGCTAGGTGACCTGGGCAGAGTGTTAAGGTTTCTGCACTTCCTCCAAGGCCTGGCCCTCCACCTCCT GCCCCTCACACCCCTCACACCCCTCACACCCAGCTTCCAGCATCTCTCTTCCCACCACCTCTCTTCCGGA CACAAGTGCACAGGGCCTGCCCCCTGCCTTGCGAGCCTAAATCCTCCCCGAAGTGCCAGGCACCTCATAG GGCTATGTTGGCGGGCTCAGGGGTGCCCCCTGGACTCACACCCCAGCCCTTGCCCAGCCTTCATTTGACT GTAAAACAAGGGATGGAGCCACCCGGAAGGGTGTGGGGCTCCTGAGGTTTCCAGAGAGCACTGCCATGCC AGCAGCGGTGAGGATCCCAGATGTGGTGGCCGTGTTCACCTTCATCCTAAGGCACTTCCAGGTACCCCGC ACGGTTCTCCTGCTCCGAACACTTTGCACCTTCTAGAGCTCTGCTCTGGTTTGGTGCTTCTGCCCCCACC CTTGGGGGACAGATTCCGTGTTCGCGCCTCACTCTGCATTTGCTGGAACCTTCGTCCTCCGGCCCCATCT TTGCTCCCTGCCTTGTGGGTCCTTCTCCCCAAACCACAGGGACCCAGGAAGGCCTCCGTGGCTGAGCAGT GGTGCGTGGGTCGCCCTGTTGGTCCGTGAGGCTTGGACGGGGAGCAGCAGCGTTGCTTGTGCTTTCTGCC GAGGTCAGCTGTCCATGGGCTGAGGGGGGCCAGCAGGGTCTGGCAGGTGCTACCTGTTCACCTCCTGGCC TGCTCCCCCCCAACCTGCTGGCCAGTTGGGCTTTGGATGTGACCCCACCCTGAGAGCTGCCCTGGGGCGT CCATCTTCTCTCCGCACAAATCTCCCTTCCCCTTCAAGCCCTGTGTGACCAGGATCTCCGACACATAAGA CAAAAGGAAATAGGGTTTTTAGAGTGGACGGGTGGGTAGAGCACCCTCCCTGACCTGTGGTCATTCTTCC AGTTCGTGCAAATGGCAAGGGGGTTATATCGAGATCTCCAAGAAGACACGGGGCGGAGGGCTGGGGTGCA GCCTGCACTTGCAGCTGCTGTGACAGCCCAGGCCAAGTCCTCCAGCTGGAGACGGGGCTACACAGATGCA CACCCCCCAGGACAAGCTTAGGGAGTCTGGGGGCGCCGCTCAGCATGGGGCTTGTTTGGGAAGCTGTGCT GAGGAGGAAGGGAAAGGGGAGTGGGGACCTCAGCCCCCCTGCTTTCATTCTTTCCTGGGTGTGTGGACCC TGGGATTCCAGCCTTCATGTCCTTCATGTCCCTGTTTCTGTCTCCTGAGAAATGCAGCAAGTCAGGCTCA GCCCACAGGCCACATGACCCTGGGTCCGACGAACAGCCAGGGCTCAAAGACAGTCAGTGCCAATGAGCCT GAAGCCTGGGCCCGGACCTCACGTTCGTCCCCAAAAATGGATCGGCTTGGGAGGAACAGTGCCCTGCCCA CCTCGCGCTGTCGCAGCCCCCCAGCAACAGTGCGAGGAGAGAATCTGCTGCTGCCCCTGGCTCCGGAGTT GTCACCCTGGCCCCCTGCTCATCTGTTGTAGGGGGGCGGGTTGCAGGGATGGGTAGGGGTTTCCTCGGTG CCTCTCCAGGCTCCCTCTGCCTCCTGCCCTGCACGGTCCTGCTCCTGTCCCTGCTCCGGCTCTGGCTTAG GGTTTGCAGGGCTGAGCTTGGCTGTTCCGTGGGTCTTGACGGAGAAAATGCAGAGCTGCACTTCCCTCCA CAAAGCCGCACTGTTCTCAGCAAATCCTCCCGGGGTCTGGTGCATTGTTTTCAAGTGATTCAGCAGCACG TGAATGGGAAGGGCCGAGCCGGAGGCTCTGGCATGAGACCTGCTGGCCCACCAGGGAAAGGGAGGGCAGC GGGACGTGGGCCCCGAGGTCCTCCCAGAGCTGCAGAGGGAGGGGGCAGGGCCCTGGGGTTGGGGAGGGCG GCAGGAAGGCTGGGCAGAGAGGGCGGCTTTGCTCTGCGTGGCTGAGGTGCTCTGATAGATGCTGTTTCCC AAGAGGAGCCAAAACGAATGGGCAGGAAGTGAGATGGGAGAGCTGGTCTCCATGGAGACGGGCACCCAGT GGCCAGCAGCTCACGTGCACTAGAATCTCAGGCAGCCGGGGAGGGAGCATTCCCTGGGGCGGCAGGGCCT GGAGCACCCCCAGGTGCCCGCTGGCAGGCGGTGTGGCCCCGGCTGAGGCTGCGCTTCTGTTCCCTGATCT CTGTTGTGCACCCTGTTACCTTCTCTGCCCCACCCTCCTCCGCACCCTCCCCAACAAAATATCTTTTCTG AGTAGTTGTCATTCCAGGCGTTTTTCACCCTGGCCTGAGTCATGCTGGCCAAGTCCTCTGTCCTCACCCT GGATGTCACGGTCCCGCCCTGCACCAGGGCTGCAAGTCACCACTGAGGGTGGACCTGGGGCCTCTCTGTC CCAGCCACCCACAAACTCTCAAGGTCAGAGTCTGGAAAGGGAGGTGGTGCCCCATGTCTTCACTTCCGGT GTCTACACCCTCAACTGGGGACGGATGTCCAGTGTGCTCCTATGGTGCCCCCTCTGCTGAGGTCTTTCCT GCTTCCCAGAAGGCCCCGTTGCTGGCTTCCGGGGGCCGAGGAGGTTGGAGGACCTGAGGGTGGGTCTGGC CTCCACAGCAGCTGCAGGGCGGGAAGAGCCTGGTTCCTGCCCAGCACCACAGGGCTGTTTTTAATTACCA AGTCACGGCCCTCTTTTCTGCTCATTTCCCTAAAAGGAGTGAATTTGGAGGAGGTCTGCCGCACCCGCTG ACCAAAAGGGGCTGGCATGAAGGGGCCGAGGAAGGGCAGAGCCCAGTGCCCGGGGGAGACCCTCTGACTG CCCACCAAGGGCACCCGGCTGTGTCACTTGAGGCCAGAGGCTGAAGGTGAGCTGGACCAGCTAACCCTCA CTGTCACCTCACAACACTTGTGACACTTCCTGGCTGCTCAGCCTTGCCCCGTGCCCCTGGGCAGTTCCGT TGGGAGAGGCGTGGCCTCCAAACCTAGAGGACTAGAGCAGGTCTGGGGTCCTTGTGAGCACAGCCCCTTC CTGGATCACCGTCTGCCATCCCTGGTGGCGTTTGTGGCCACTTCTGCTGCTCCAGCTGGCGAGGTCGGCC CCATCCTGCTAAAAGAAGGAGGTGCTGCCCGAATGGAGAGCTTCCATGTTTCTAAGCTGTCTTTACTGTG ATCCTGAAGCCCAACGAGATTAGTTACACACAAACATTTAGGGATCCCACAGCGATCTGAGAGCAGGGCC ATGAAAAATAGTCATTTATTACAGCAGTTGCAGGGCAGGGCCACAGCTGTGTTACTGGACATCTGTCCTG AGCTGAGGGTGTAGACACCAGAAGTGGGGAAAGTGGGCTTCACCTCCCTTTTCAGACTCTGATCTTGTGG GTGGCTGGGGCAGAGGGGCCCCTGGTACACCCTCAGCTGGCGCTTTAGACATATTAATCAAAATGGTCAG GCCGGGCCAGGTGGCTCACGCCTGTAATCCCAGCACTCTGGGAGGCCAAGATGGGTGGATCACGTGAGGT CAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACACAAAATAAAAAT CAGCCGGGCATGGTGGCGGGCACCTGTAATCCCAGCTACTCCAGAGGCTGAGGCAGGAGAATCGCTTGAA CCCAGGAGGCCGAGGTTGCAGTGAGCCAACGTCGTGCCATTGCATTCCAGCCTGGGCGACAAGAGCGAAA CTCTATCTCAAAAAAAAAAGAGGATATGGAGCCCCTGCCAGGTTGACCAGCCATATGGTGTCATTACATC CACCCAAAAGGGACAAGAGACTCTCATCCCCAATGGCAACGCCAAGTTATAGTTACAGATGTTAGCAAGG GCGTTACTAACTGTGTGATTTGAGGGTGTGGACATTGGCACTCATGGCACCCCACTTTTCTGGAGAGTTT AGACAAGGCGTGGAACGTCACAGTCCTTTCCCAGTGAAAGAACAAAGCTGAGTCCACCTGCAACTGCCAT TGGATCCTCCCCAGGAGTAAGTGGAGGTTGGGTTTCATCCGGGAGAGAAAATGGTTTCTTTGATAATTCC TCTGAAATGACTGGCATGTAATTCCACCCAGAGCCAAATGAACCAAATGACGCTCAGAAGACGTCTGCGG CTCCGGCCTGCAGTTACCGCGTTTGCGTCTACGCAGTGTGGAGTCCTCCAGGGCTGGCCCCTGGGATGCA TGCAGTGGCCACTGGTCTTCATTGCCACTGTGGGTGCTCTGGGCTGACTCTGACCCAGCTGCAGCATCAG AATGCCCCCCACCCACTAGTGATGTGGGCCAGTAGGGTCTTTGGCACATGTGTGAAGCCCCCACCCGACT CCCAGGAATGACCCATGTTGAGAACATGGGGACCCCTTGGCGTTCTCCGCTGGGCCATAAGCAGGACAGG ACAGAGGGGAAGGAGGCGCTTTCCCTGCCAGTGCTGGTCCTATGGGCGCCCCTCCCCAGGTGAAAGCTGG AGCCTGCAGAAGAGGGTGGACGGCTGGGAGGGGCCAGTGCCCTCCAGTGATACTGAGCAAACCCTCCCAG TCCGAGTCAGTGTGCACACAAGGTGCAGATGATCGGGCCGGGTTTTGACTTTGTATTTAGCAGCCGAATG TGTTTCTGAGTCCCAGGGATCCCTGCACCTCGTCTGGGCAGACAGGTGACTTTGAGGGACAGTGGGCCAC CTTCTCCCGCTGCCTGAGCACGTCCCGTAGCCGAGACAGGCGCTATGCTGTTACAGTGTGTGGAGTGCCC CGGGGAGAGGCTGTGAGTGGTCTAGACGTTGGGTGTTGATATCCACCGGTTTGCCTGTCCCAAACTTGGG CCTGGGAGCCCGGCAGAGTGGCTCAAGTGGAAAATGTTCTATATGGTATATTTATACATATAGCATGTGG GATTCCTCCAGCGAGCAGTTGGGCCCCTGGCAAGATAATAAAGAGAATTCAATGAGTGTGGAATAAGTAC ATTTCTTACAGGCAATTTTCTTTTTCTTTCAAAGGCAGGGTCTGGTTCTTTCACCCAGGACCGAGGTGCA GTGGTGCATTCATAGCTCACTGCAGCCTTGAACATCTAGTTCATACAATTCTCCTGAGTAGCTGGGACTA TAGGCAGATGCCACCACGCCCAGCTAATTTTTGTTTTTTTTTGTTTTTGTTTTTTGTATTTTGTTTTTTA TAGATGAGGTATTGCTATGTTGCTCAGGCTGGTCTTGAACTCCTAGCTTCAAGCAACCCATCCACCTTGG CCTCCCAAGTGCTGGGATTACAAGTGTGAGCCACTGCACCCGGCCTTTCGAGGCAATTTTCTTTTGGGGT CTGTCTCCCTCCCCCAATTGTGGGCATGGCTTGTTCTTATTTTCCGCAGGAACTTCCATAGTACTTCTGT GGACACAGGAGGATTGGAAAGATGTTGGTGGGTGTATGAAGGGGACGTGAGGACGCAGGACCCACGTGTT GATGGCAGCAGAGGGGACACCGAGGAGAGAGAACAAGGGAGGACCGTGCCACAGAAGCCGTGGCGTCTCT GCCTGGGGCTGGCGTGGTTGGAGTCTGTGGAGAGTGCCGCCCCTCCGGCCAGCCCTTGGCCCTGGCACAT GCTGGTGACACCAGGTTCTCCAGCAAGCCCCCTTCACTGTCTGCTCCCCTCCGAGAGCAGCAGCAGCCGG TCCGGCCTCTGATGGTTTTCCAGGGGCGGTTGTGACTGTCGAAGTCTGACCGTAGCCCATCCTCTTTGGA TCGTCTCCCGCGACCTTGGTTTTCCGCCCACCCGGTTCTTTTCCGTCCCCACTCTGGCGGGTGCGCTCGG GATTGTTTTTGCAGGGGGGAAGTGACATCATATGGTGTCCTGGGCTGGAGGGGTGGGGGTGGGGACCCTG CAGTTGCGTGTGCTTTGAATTCAGCCGACGGTTGTACATTCCAGTAGCCGGCATCTGGCGGTGAATTCAT CAGCCAGTGTATCACCCTTGATCTCAAACCCAGATGTTGTGTTCACAGCAGAAGGGAAAGAAGGAAAAAC GAAATCTGAGACGCCCAGGGAGAGGCCGTGGTTTCTGGGCTCAGGGCAGTTAGAACGAGAGTCTTTATAA AGACTCCCCCTCTCGCAGCTGCCTCTGGCTCCTTGGGGAAGGGGCAGAGGAGCAGAGCAGCCCCTCTCGG GGGCATGGACAGGAGATGGGCTGACACCCACCCCAGTGCCTAACACCAGGCCCAGCACCCAGTAGGTGTT CAGTAAACGTGTCTGTGCCACAATTTTCATTTCTTCCCAGATTCCTTATGTCTCTTCGCTTTCCCCAGCC CTGTTCTTCACATGGCCTGGGACTCGGAGAGGCCCTCCCTCTTTTGAAGTGGCCTGCTTTCCCCTACAGA ACTGGTGGTCCATCCTGGAGCTCAGAGTGCGGACCATTGCCATTGGCATGGAAATGTATTCCGGAGAGCT CTCTCTCCCTCCTCCTCTGTCCACCACTGGGCATTGGAAACTCTCCTTCTCTGTGTTCCTATCCATCGTC TGTCATCTTGCCTGGATTGGATGCTCCTCCCAGGCAAGGCCTGCTGTATGCAGGATTCACCCTGTACCCT CTCTTCACCTGCTGTCACCTCTGGGCAACAACCCCCGACAGGTACCCGCTGCTCTGAGCAGGTCAGCGGT GCAGATCCCGCTATGCCAACTGGTGTGCACCGATCAGAGCTGTCAGCTGGCCCCTCTCCTTCATGTCTGC GGCGTGCTGGTGCTTTGGGGAAGGTTGCCGTGGAACTGGTCCTTCTTTGCCTCTCTTGATTCCCATTTTC CTTCTTTCATGTAATTTCTCATTTTGCAAAGTGGGGGAGGAGGTGCCCACCCCCAATTTAAAGGGACCCT GAAGAATCTGAATTCTGTTCCCCAGGGGCAGACTAAAGCAGCCCAGGGGAGATGGAGATGCCCTCAGGCT CTGCTCCTCCAGGCCCCTCACCCCCACTTCCCTGCCCCTCACCCCCACTTCCCTGCAGGCATCTGGCGGC CTCCTCGCCAGTTCACTTTCTAGTCCTAACCCCACGTGGCTACCCTGGACCCTTGATTTGACCAGCCTCC TCTTTTCTGACACTTTAAAGAAGGAAAGTGTGTAATCTGCAGCCCCCAGGCAAAGCTAGCACGCTGGGAA GCTGCATCAAATCGAGAGTCTGTGGCCTGCTGACCAGGACCGGGTCTGTGTACCTGAGTGGCATGATGCC ACCGTCCCAATCCCTCACCCACGGGAGCGGGAGAATTCGCCCTGCTTGTCTATGCGATGCTCGTGGTCCT GAACTGTACACGCATTAGTTCCCGGGCACCGCAGCCTCCACACCAGCCCCTCTAACAGTCACCACGACCT TGTGAAGTGTCAAGACTGTTGTCATCGTCTCTGTCTTAGGTGTGAACAACTGTGGCTCAGTGAAGTCAAG GAGCTTCTCAAAGATCACGCAGCCATCCAGGGGTGAATGCAGGATCTCTGTCTCTTGCTGCCTCCTTCAA ATAAGTGCCCAGCTGCCACCTGGGAGCCTTAGGCGTTTTTGTAAGAGAACAGCATGTGAACCTCAATGCC CATGGTAGGATGCAACATTTTGGCCGTTTTGAAGTAATCTTTGCTTATTTTCTGAACTCCAGTGACATGC TTGTTGAGTGCCTATTGTGCGTTAAGCATTGTGCGGCTTAGTGGACCATTGAAAGGCAGCTCCAAGGCCG GGCGCGGTAGCTCATGCCTGTAATCCCAGCACGTTGGGAGGCCGAGGCAGGCGGATCACGAGGTCAGGAG TTCAAGACCATCCTGGCCAGCATGGTGAAACCCCGTCTCTACTAAAATAAATACAAAAAATTAGCCGGGC ATGGTGGCGCGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGG CGGAGGTTGCAGTGGGCCAAGATTGCACCATTGCACTCCAGCCTGGATGACAGAGCTAGACTCCATCTCA AAAAAAAAAAAAAGAAAGAAAGAAAAGAAAAGCAGCTCCAGAAATTTCCAAAATAACATACAGAATTCAG CAGACTGTAATAAAGGCCGGCTTGCTGCTCCTACTGGAACTGTTGATTCCTTTGGATTCTGCTGGCTTGC TTTTTTTCCTTTTCTTTCTTTTCTTTTTTTAAAAGACGGAGTCTCACTCTGTTGCCCAGGCTGGAGTGCA GTGGCATGATCTCAGCTCACTGCAACTTTCACCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCA AGTGGCTGGGATTTTTGTATTTTTTGTAGAGATGGGGTTTCACCATGTTGGCTAGGCTGGTCTCAAACTC CTGACCTCAAGTGATCCGCCCGCCTCGGCCTCCCGAAGTGCTGGGATTATAGGAGTGAGCCACCGTGCCT GGCCCTGGTTTGCTTGTGAGCTGGTGACTCTGCTACATGAAGAGCAAACTTTGACCAAGTTAATCTGGCA CATTGACTAATTTGCATAAACATTTTTGGTGCAGCATTGTCGTAAGGTATATAGATTAGGCAGGGAGCAA GAGAGCCAAGGACAAACTGCACCTGGGCCACCAGCCCAAAGTTGTCAGCGTCATCTCAGCTCCATCTGGC AAAGAGTTAGTGAGCACCAACTGTTCTGCAGTCAGAATCTAGCCTCAACCTGTTAGGACCTCCCAGGGCC CTGAGCAGACAGGTGTGCAGGAACTGACAGCAGGATGGAAAAGAGATGGGGAATATACCAAGTGCTGCAG AAGGACAGGATTTCCCAGAGGAAGACAGAAAAGGGCTATTTTAGCTGGGTCTTGAAGAATGAAGAAAAGT TCTCCAGGCAGAGAGGGGAGATGGCATTTGGGGCGGAAGAAACTTGCCTGTTCAGGCTGGGTGTGGTGGC TCACACCTGTAATCCCAGCACTTTGGGAGGCCAAAGTGGGCGGATCACTTGAGGTCAGGAGTTCGAGACC AGCCTGGCCAACATGCTAAAACCCTGTCTCTACTAAAAATACCAAAAAAAAAAAAAATTAGCCTGGCAAG GTGGCAGTTACCTGTAACCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAACCTGGGAGGTGG AGGTTGCAGTGAGCTGAGATCAAGCCATTGCACTCCAGCCTGGGTGACAAAAGTGAAACTCCGTCTCAAA AAAATATATATGGTAATTAGCCAGGCATGGTGGTGCCCACCTGTAATCCCAGCTACCTGGGAAGCTAAGG CAGGAGAGTCATTTGAACCTGGGAGATGGCTGAGATTGCGCCACTGCACTCCAGCCTAGCAGGGGTGGGG ATGACAGAGCAAGACTCTGTCTAAAAAAAAAAGAAAGAAAGAAACTTGTCTGTTCAGAGGTGTGGATGCA CCTGGGCGTGTTCAGGGCAGACAAGTATTATGAAGTGGTAGAATAGTGGGAGCATGGGTGGGGGGTGTTG GGCACAGCAGCTGAGGCCCCTGGCTGACTTCAGGTTGCAAAGGCGCTCATATTTTAGGGGAGGGCAGGGG GCAGCCAAGGATGATGTTTGAGCAGAAACGAACGTGAATAAAAAAAGACAGCTGGTTGCGGTGGATGAGA GGATGGTTAGGAGGGCACTGGAAATAGGGGGCCGTCAGGGCAAAGCCGTCTGTTCTGGAGTGGCCTGCCG GGAGACATTTCCTAGATGTGGCTTTTCAGGATGAGGCATGGATTAGCCTGGGAAACAGGAACCTGTGGCC TTGGCCAGTCATGACTCAGCTCCAACAGAAGAAGAAAGAAGAAAGGGGTTTGTGCCCAGGCGAGGCAGTG GGGCTGTGGTGTGGGACTCTGATGCCAGCCTGGGATCCAGAGAGCATTGGTGGGGCCCAGGGGGATGGAC ACAGATGGAGCACCCACACGCCTGAGCCTCCTTGCCCCTGTGGGAAGAGACAGCCCTGCCTAAGGGGTTC TAAGAGATTTGAGCCGACCACGTGGGGTGGGGCTGGGGCTGGGGCTAGGAGGCTGCCTGGAGCCTGGCGT GGTCTGCTCCTTACCTCTCTGTTTTGCTCATATCCACCGTAACATAACACTTACCCAGAGTGACCCTGAA GAGCTGAGTTTGGGAGGGCAAAGCTTTTAAAGCCATTAAAACAGACCATGTCACCAACTAATGGCCTTGA AATTAAGAAAGGGAGGGCTCTACCCAACCCTGCCCAAGTGACAGCATGAACTACTGATCTGCTTGTCCTC AGGTTACCAGGAGTGGAACAGAATCCTGGCTTAATTGCTAGGAGAAAGCCCTGTGTTGCATGGCCTGTCA GCAACCTCAGGCTCCAGAATATTCTGGAATTGCCCCAGCCCAGCCTCTTCCCCAACTCCTTTCTGTTTGG TTGGGGCTTAGTTGGGATCCTCTTTCCTTCTGTTTGTCCTTCCTCAGCATCTGTCCCTTGGGTCTGCCAG CTGTGCCTGCCGATGTCTCCTTTGGGTGAAACTTCCTGCCCCTGCCCCTGTTGTGCCCCTGATAGACTCT GTGTTACTGTAAAGAATCACCCAGGCTGGGCGCAGTGGCTCACGCCTGTAATCTCAGCACTTTGGGAGGC CGAAGCAGGTGGATCATTTGAAGTCAGGAGTTCGAGAACAGCCTGGCCAACATGATGAAACCCTGTCTCT ACTAAAAATACAAAAATTAAGGTTGGGCACTGTAGCTCATGCCTATAATCCCAGCACTTTGGGAGGCTGA GGCAGGTGGATCACCTGAGGTCAGGAGCTCAAGACCAGCCTGGCCAACATGGCGAAACGCTTTCTCTACT AAAAATACAAAAATTAGCTGGGTGTGGTGGCAGCTGCCTATAATCAGAGCTACTTGAGAAGCTGAGGCAG GAGAATTTCTTGAACCCAGGAGGCAGAAGTTGCAGTGAGCCAAGATCATGCCACTGCACTCTAGCCTGGA CGACAGAGTGAGACTCCGTCTGAAAAAAAAAAAAAATTAACCGGGCGTGGTGACAGACGCCTGTAATCCC AGCTACTTGAGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGATAGAGGTTGCAGTGAGCCAAAACG GTGCCACTGCACTCCAGCCTGGGCAACAGCGCGAGACTCCATCTCAATAACAACAACAACAAAAATTACT CATAGAACATTTTCCAGGTCAGGAAAGATGAGAAGAGCTGGATAGACCTTTCCAGATGTAAGACCCCCAA AGCTAAATATGCCGGGTACGTTTAAGGCCCCTTTAAGGTGGATAACTCCCCCTCTGCCCTCAGCCCAGAA AAGCTTGTTTCCAATAGGCCGTGGCTGGAGGGTGGGGAAATGTCCCATCCTTCGCGGAATGTGTGGGATT GTGGGTCAGTTCCATGGGGTACCTGCTTGCCCCAGCCACCAGTGAGTACCCACTGGAGAGAAGGAAAAAA AAAGCCAAAAGCACTCAAGCATGATATCAACAGATGAGCTTCAGTCAAATCAATGACTGCCTCCCACTGT TACAGAAACTGCCTTGGTCACAAGGGACTCTGGGCTTCTGGCTTGGGCCCCTGTCAACAAAGAAGGGATT CTTGTTGAAGAATCGTGGAAGGAGGAGGAGGAGGCTGGGCATCATCTCTCAGCCTGGAGGAGGAGACGCC ATGCCGGGGGCTGGGATCACCATGCCCCTTGCCCGTCTCGCACCTTGCTGCTGTCTGTAACCCCCCAGCA CCTCCCGCAGGCCTGGACGTCTTATCCCTCTCCTTAGCCCCAGGAGCGTGTTTCAGGAACTCTCCTCACC TCTGTGTCTTGTGTTTTGCAGTGATCAGGGCCAAAGCGGTCAGTGAGAAGGAAGTGGACTCTGGAAACGA CATTTATGGCAACCCTATCAAGAGGATCCAGTATGAGATCAAGCAGATAAAGGTAATAGTGGCTGCCGGC ATCCCGGGCTGCACTGTGGGCACAGCTGTGGGGTGTTGGGGTTGGCAGAGAGCCTGGGTCCCTGGAACAC GATCTGGCCACCTGTGGACTAGAGCAGAGGATGAGGTCATCAAGCTGCAAATAGATCCGATTTCCCTTAA TCCTCGAATGCCTGAAAAGTTGTGTGGAGATGACATGCTCCCCACAAATTCAATTCCTTCAGAAACCTGT CCGGGCGTTGCGGCTCACACCTGTAATCCCAGCACTTCGGGAGGCCGAGGTGGGCGGATCACTTGAGCTC AGGAGTTCAAGACCAGTCTGGGCAACATGGTGAAAATCCATCTCTACAAAAAACCAGCCAGGCATGGTAG CGCCCACCTGTGGTCCCAGCTATTCGGGAGGCTGAGGTGGGAGAATCGCTTAAGCCCAGGAGGCAGAGGT TGCAGTGAGACATCTCACCACTGTATTCCAGCCTGGGTGACAGAGTGAGAGCTTGTATTAAAAAAAAAAA AAAAAAATATGTGGCAGGGAGGGCAGGGAGGGCAGGGCCTGGCCTGGGGCAGGAGAGGTGATGCTATTGT CATTGACAGTAACTAACATGGTCTGTAAGAGAGACGAAAATTCATGTCGCAGGTGGAGGGACAGCCGTGT GATATGGTGGTAGTTGTAGTCATCGATATTTAATTTTGTCATTAAAAATAAAAAGTAAACCAGGCACAGT GTCTCATGAGTATAGTCCCAGGTGAGTGGATCACCTGAAGTCAGGAGTTCAAGACCAGCCTGGCCAACAT GGAGAAACCCCATGTATCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGCGAGTGCCTGTGATCCCA GCTACTTGGGAGGCTGAGGCAGGAGAACACTTAAACCTGGGAGGCAGAGGTTGCCGTGAGCTGAGATTGC ACCACTGCATTCCAGCCTGTGCGACAAGAGCGAAACTCCATCTCAAAAAAAGAAAAAAAAAAAAGTAGCT GAAAATCAATGTTATCAGAAGGTCAGTGGAATGCTTCATCATCACATGTATGTCAGTTTAAGGGGATGAC CTAGTCTCTCAGTGCCTGAGTCTCTTTCTTTACGAAGCAGGAAAGAGGATCTGCTCTTACGACCTCATAA AGGGGTCGTGAAAAGGCCAGTGCCAGTGCCCAGGAAATGCTTTTAGCCTTTTGGCAAATGATGTCATTTA GTACAGCATCAACATAACCTTTCCTGGTACAAGCTGGAGTGTCACTCTCAAGCCATTTGTCATGACATCA GGCATGCTTCCATTCCATTTGGGTTTGCTTATTGAAACTCTTCGGGGGGAAAAAAACAGCCTCCCTGAGT GCTGAGAAAATGCCATTCTTCACCTGGGCAGCAGGTGCGTTCCTGAAAGGCTGTGAGTAAATCACATGTT GAGAAAGCAAACTCTTCTGGCCCATGGAGTTATGTCCTAATTCCTGAGGTGCCTCTCTGCTCTCATTGCC ATCAAGTAGACAATATTTGACCAAAATTCCTGGAAATATAGGTTGGGTGGAGTGACTTATGCCTGTAATC CCAGAACTTTGGGAGGCCGAGGCAGGAGGATTGCTTGAGCTCAGGAGTTTGAGACCAGCCTGGGTAATAG AGCGAGACCTCGTCTCTGCTAATTAAAAAAAAAAAAAAGCCAAGCATGGTGGCATGCGCCTATAGTCCCA GCTACTCGGGAGGCTGAGGTGGGAGGATCACTTGAGCCTGGGAAGTTGAGGTTGCAGCCCCAGCCTGAGC AACAGAGTGAGACCCTATCTCAAAAAAATAAAAAATTCCTGGAAATATGCAAAAGTCATGGTCCTTCATG GTGGTCCAGAGTCACGTGGAGGTACAAAAGCCCCTCCCCATAGATTCAGAAATGACCTCTTTGGGGTGGG GGGTGAGGGAACAGAGGTGTTGTCTGAGGATGTCATGCTCCAGATGACAGTCTTTTTTTTTTTTTTTGAG ATGGAGTCTTGCTGTCTCCCAGGCTGGAGCGCAGTGGCACGATCATGGCTCACTGCAAGCTCCGCCTCCT GGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCACGCCCAG CTAAATTTCTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTAGCCAGGATGGTGTCGATCTTCTGACC TCGTGATCTGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACTGGTGTGAGCCACTTCGCCCGGCACAGA TGAGTCTTGTGCTCACCTGCTGTGATCTGCCACACTAAAAGTTGAGTGACTCCAAAGAATCACTTTGCTA TAAGAAGTCTTTTTCTTTTCTTTTTTTTTTTTTTTTTTTTTGACGGAGTCTTACTCTGTCATACAGGTAG GAGTACAGTGGCGCCATCTCAGCTCACTGCAACCTCCACCTCGCAGGTTCAAGCGATTCTCCTGCCTCAG CCTCCCACATAGCTGGGATTACAGGCGCTTGCCACCATGCTCAGCTAATTTTTGTATTTTTAGTAGAAAC AGGGTTTTGCTACGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGCGACCTGCCCACCTCAGCCTCC CAAAGTGCTGGGACTACAGCCATGAGCCCTGAGCCCAGCTGGAACGGTCTTTTCCTAACCCATGTATTTG CACTTCCTGGTCCTCTTGGGTGCTGGCTGTACCCCAGCTACAGGTTGTGCCGCCCAGGGTGTTCTGGATG GGAACGGAATTCACCAACTGTGTGGCCTCCCTCTGCTTACATGTCCTCCTCCTTGTCTTTCCAGATGTTC AAAGGGCCTGAGAAGGATATAGAGTTTATCTACACGGCCCCCTCCTCGGCAGTGTGTGGGGTCTCGCTGG ACGTTGGAGGAAAGAAGGAATATCTCATTGCAGGTGTGTATGAGTGGGGCCATCAGCCGGAGGCTGGCAC AGAAGTGGGGCTGTTCCTAGACGCGGTCCAGGGCTCGTTTCCCAGGCTCGGGGGGTGGGGAGGCGGAGTA GCTGAGGAACAGTGAGGCAGGGTACGGAGCCCTCTCGGCCACTTCCCGTCAGAGAATGCTAGTGAATGTT CACTACCTGCCAATTTCCTGGGAAATTTGAGATTGGTGGACAAAAAAAAGGGAGCATTTTTGCCTTTTGT TCCTAAAAGGGAGGCGAGTGCGGGATGCTGGAGACATGCAGGGCAGAGAAACCCTTTCTGCCGTCGGGAG GGCCAAAAGCTCGCGTAACATCTGTGGATACTATGCACGAGACCTGCTTGACTTATTCATTCATCTGTCT CCTTTTTTTATTGTGGTAAAATAATACGTAACAAAATGTAGCCATGTTAATTAACCATTTTCTTTCTTTC TTTCTTTCTTTCTTTCTTTTTTTTTGAGACAGAGTGTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGC GATCTTGGCTTACTGCAACCTCCACCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGTT GGGATTACAGGCACACGCCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTCTACCGTG TTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCACCTCGGCCTCCCAAAGTGGCAGGAT TACAGGCGCGAGCCACCGCGCCCGGCCAACCATTTTCAAGTGTACACTTCAGTGGCATTAGATACATTCG CTATTGTGCAACCATCACCACCATCTGTCTCCACATCTTCCCAAACCAAAACTCCGTCCCCGTTAAACAC TAACTCCCCCTTCTCTCTTCCTCAGCCTTGGCCCACCTCCATTTTACTTTCTGTCTCTGTGGATTTGACT ACTCCAGGGGCCTCACATGGGTGGAACCCTGCAGTGTTTGTCCTCTCTGTCTGGCTTATTTCAGTAGCAT CATGTTTTCAAGGTTCGTTCACGTTACAGCATACATCAGAATTTCCTTACTCTTTTTTTTGTTTTTGAGA CAGAGTCTCGCTCTATTTCCCAGGCTGGGGTGCAATGGCACTATCTCGGCTCACTGCAACCTCCGCTTCC CAGGTTCAAGCGATTCTCCTGCCTCAGCCTCTCAAGTAGCTGGGATTATAGGCACACGCCACCACACCTG GCTAATTTTTTTTTGTATTTTTAGTACAGACAGGGTTTCACCACGTTGACCAGGCTGGTCTCCAACTTCT GACCTCAGGTGATCCGCCCACCTCAGCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACCACACCCGG CCCAAAATGTCCTTACTTTTTAAGGATGAATAATATTTCATTGTATGAATGTAGCACATTTTGTTTATTG TTGCATCTCTTTGTTTATAGTTTTTTGGTTTGTTTTTTTTTTTTTTGAGACAAAGTCTTGCTCTGTTTCC CAGGCTGGAGTGCGATCATGACTCACTGCAACCTCGATCTCCTGGGGTCAAGTGATCCTCTCGCCTCAGC CTCCCAAAGTGCTGAGATCAACTACAGGTGTGTGCCACCACACCCAGCTAATTTTTTTATTTTTTGGTAA AGAAGTCTCACCATGTTGCCCAGGCTGGTCTTGAACTCCGAGGCTCAAGCAATCCTCCTGCCTCAGCCTC CCAAAGTACTGGGATTATAGGCGTGAGCCACTGTGCCCAGCCTATATTTTTATTCCTAAGTAAAATTATT TTCCCTTACTTCCTTCTACGGCCTCCTCTGCTTGCCCAGCTAGGCTGAACCACAGGAGGCCAGGACAGGA TTCTCAATCTCAGCACTATTAACATTTGGGGATGGACCATTCTTTGTTGTGGGGGCCTACCTTATGCATT ATAGGATATTCAGCTGCATCCCTGGCCCCCACCCTCTACATGCCACAGCACCCGCTCCAGTCGCGGGGTC TCTGGACATTGCCACATGTGCCCAGGGGAGGTGGGGTAGATTGCCCCTGCTTGAGAACCACTGGGCTCAA AGAGCTTTCTGCAGTGATGGAAGCGGTCTCTGCACCATCCAGTCCAGCAGCCCCCAGCCTTGTGGCTCAT GAGCACCCGAGATATGGCTAGTGCAGCCGAGGAGCTGCATTTTAAATTTTATTTCATTTCAAGTAATTTT AGTATAAATGTAAACAGCCACATGTGGCCGGCAGCCGCAGTCTAGCATGGCACTGACTCAGCCAGTTAAG GAACATTATTCCCCTCCTCCCTGGGGAAGTAGGAATCTGATCACAAACTTAAGAAAAAAAGAATAGACAA GGCCTGGTGCAGTGGCTCATGGCTGTAATCCCAGCAATGTAGGAGGCTGAGGCGGGCGGATTGCTTGAGG TCAGGAGTTCAAGACCAGCCTTGCCAACATGGTAAAACCCTGTCTGTACTAAAAATACAAAAATTAGCTG GGCGTGGTGGCAAGTGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCATGAGAATCATTTGAACCCAGG AGGCAGAGATTGCAGCAAGCTGAGATCACGCCACTGTACTCCAGCCTGGGTGACTGAGCAAGACCCCATC TCACAAAAAAAAAAGAGAAAAGAAAGAAGAGACAAGACAATTCCCCTAGCCTGGTACTATAGTTTGTTCC AAAAGGCAACTGTAATCATAAACATATACTCCAAATCCAAATATCCATGATTGGGGGATTTTCTTCTGGT TTAGGTGACATGTACTTTTTTCCCTTCTAAAAATCAATGTGTGCTTAGTGAGCACCTGTTAGGTGCCCAG CCCCGTGTTAGAGACAATGGGAGATTCCCACGGTGAGATCCTTGGCTCTGGTCATCATGGAGCACACAGA TGTTCCGAATGGGGAGACTGGAAAAGAAAGAAAATAGATTTTGCTTGTGGAGAATTGTGAATAGTAAGTG AATGCTTAGAAGGTGCAAAAGGGGCCGGGCGAGGTGGCTCACGCCTGTAATCCTAGCACTTTGGGAGGCC GAGACGGGCAGATCATGAGGTCAGGAGATTGAGACCATCCTGGCTAACACAGTGAAACCCCGTTTCCACT GAAAATACAAAAAAAAAATTAGCCGGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCAAGAGGCTGA GGCAGGAGAATGGCGTGAACCCGGGAGGCGGAACTTGTAGTGAGCCGAGATCGTGCCACTGCACTCCAGT CTGGGCGACAGAGTGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAGAAGGTACAAAAGGAAGAGAGACT CTCACAGGTCCAAGGGTCTAGACAGACTTGCTGCTGGAAGAAGGTGGTGTCCTTGCCTATGGATGGGGAG GAGGTCATTGCAGGGAGGAAGATGCAGGGCTGTGAGTTGGGCAGGGAAGACTCCTGTTATCTCCCCTTGG GTAAGATCTTCCCTCCCTTCCTTAACATGCTCACAGCTCCTGCTTTGCTGGGTATCTCGGTCATCAAGAC TTCTATCCCTCTCCTTGGGGATAATAGGAGACTTCCCCCCCTTTTAAGATGCATTTCTGGACTTCCTAAA ATGTTTTATTATGAGCACTTTTCTTATTCTCATTCCAAGACAGAGTCTCCCTCTGTTGCCCAGGCTGGAA TGCAGTGGTGTGATCTTGGCTCACAGCAACCTCTGCCTCCTGGGCAATTCTCGTGCCTCAGCCACCCAAG TAGCTGGGATTACAGATGTGTGCCCCCATACCTGGCTAATTTTTGTATTTTTAGTAGATACGGGGTTTCA CCATGTTGGCCAGGCTGGTCTTGAACTCCTGACTTCAGGTGATCTGCCCGCCTAGGCCTTCCAAAGTGCT GGGATTACAGGCGTGAGCCACCGCGCCCGGCCTACAATTCAGTGGTTTTAGTATGTCACAGAGTTCTGCA ACCATCACTACAGTCAAAAAGAAATCCTGTATTCTTGAGCTATTACCCTCCTGACTCCCCTCCCCCTCCC CCAGCCCTAAGCAGCCACTGGTATACTTCCCGTCTCTATAGATTTCTCTATGCTGGGCTTTCCTGGGAAC GGAATCATACGTGTGACCCTGTGTAACCGGCTTCTTTCGTGTTTCCAAGGGTCATCCATGTTACAGTGTG TATCAGAATTTCATTCCTTTCTATGACTGAGTATTCCACTGTATGGATAGACCACGTTTTGTTTATCCGG TCATCATTTGATGTGCATTTGGGTTGTTGCCACCGTTTGGCCATTGTGACAAATACTGCAATGAACATTG GTGTGTGAGATTTTGCAGGGACCTGTTCTCATTTTTCCTGGGTGTATCCCTGGCAGTGGAATTGGTGGGG TCGGGGGTGGGGAGGGGTTGGGTGACTTTAGGTTTAACCATTTGAGGAGCTGGCAGACCGTTTTCCAAAG CAGCTGCACCATTTTACACGCCCAGTATTATCTATGATTTTTACAATAAGAAAAAAAAAATCAAATGGAG AAGGGTAGAGGGACAAAAACCACCTGTGGTGCAAAGATCTTACCAGCTAACTAATGCCCTCAAAAAAAAC ACAGAGGAGGCAGGAGAGCTGGGGTGGCCGCACAGCACGCACGGTGGCGCGTGGCAGAGGCATGGTCTGC AGTGTGGCATTCGGGGGCTGCTGCAGCTGTGCACAGAACAGAGCACGGGAGGAAATTTCCCAGCGTGTCA GCATCTGCTGTGTCTCCTTTTCAGTTCTTTCCTGTATTAAACCTTTAAAATTATGGCATTTATTACGTTT GTCATCAGAAAAATAAAATCTGGAGAGACAAGAAAGGAGACAGAATCCCCCGTGGTGCAGGGAACTTACT TCCAGTTTTCTGCATCCTGTTTGTTCCTATCCACAGGGAACAGCCTTTAAAGTAAGTCCCAGCCGTCCCA GCTCAGTTTCGTCACACTGCCCTCTAGGGGCTTTCTGGCCAAACTGCAGCGCTGCGGAAGGACTCTTGGG TGCAAAAGTGACCTTGGTCTGAGCCAGCACCGGTGTCCAAACATACCCAGCTGAATCCTCGCCCATGCTG AAGCTCTCTGTTTGTTTTTGTTTTTGTTCGAGATGGAGTCTCTCTCTGTTGCCCAGGCTGGAGTGCAGTG GCACAATCTCGGGTCACTGCAATCTCTGCCTCCCGGGTTCAAGCAGTTCTCCTGCCTCAGCCTCCCAAGT AGCTGGGATTACAGGTGCCCAACACCACGCCCAGCTAATTTTTTTTTTTTTTTTTTGAGACAGAGTTTCT GTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGGTCTCAACTCACCACAACCTCTGCCTCCCGGGTTCAA GTGATTCTCCTGCCTCAGCCTTCCGAGTAGCAGGGATTACAGGCATGTGCCACCACGCCTGGCTAATTTT GTATTTTTAGTAGAGACGGGATTTCTCTGTGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATC CGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCACCTGGGCGGCATTAAGTAC ATTCACAGTGTTGTGTAACTATCACTATCTATTTCTAGAAGTTTTTCATCATCCCAAACTGAAACTCTCT CCCCATTAACCAATAATTCCCTGTTCCTCTGTTTGCCCAGCCCCTGACAACCACCTTTCTACTTCGTCTC CATGAATTTGCCCATTCTAGACACCTCGTACAGGTAGAGTCATACCTCCTTCCATAGCTGAAGCATTGCA CTTAGCATAATGTCCTCAAGTTCATCCATGTTGTAGCATGGGTCAGATTTTATTTTATTTTATTTATTTA TGAGACGGAGGCAACAAAGCCCAGGCTGGAGTGCAGTGGCGCGATCTTGGCTCACTGCAACTTCCGCCCC CCAGGTTCAAGCAATTTTCCTGCCTCAGCCTCCTGAGTAGCTGAGGTTACAGGCATGCACCACCACGCCC AGCTAATTTTTGTATTTTTTTAGTAGAGACGGGGTTTCATCATGTTGGTCAGGCTGGTCTTGAACTCCTG ACCTCAGGTGATCCGCCTGCCTTGGCTTCCCAAAGTGCTGAGATTACAGGCTTGAACCACTGCACCCGGC TGGTAGATTTTATTTCTTTTTATGTGCATACATTTTAAAGTTTCCAAAATATGTAATACTCTTCTAAGTT GAATTCTATATATGTTTTCAAATTGTTAACATTTCCATTAACTTTTTAACTCAGATACTACTTAGTATCT CAAGGAGGAGGCACGAGGTTTTGATGAGGACACAGAACTAAAGGTGCCAAGTGCAAACAGTTTATTGCAT AAAGAAAATAAGGAAATGGGCTGACCATAGTGGCTCACACCTGTAATCCTAGCATTTTGGGAGGCTGAGG CAGGAGGATGGCTTCAGGTTAGGAGTTCAAGATCAGCCTGGACGATATAGCAAGACCCTATCTCTACAAA ACAGGAAGGGAGGAAGGAAGGAAGGAAGGAAGGGAGGGAGGAAGGGGGAGGGAGGCATGGAGGAAGGGAG GAAGGGAAGGAGGGAGGGAGTGAAGGGAGTCAGGGAGAGAGGGAGAGAGGCAGGGAAGAAAGGAGGGAGG GAAGAAGAAGGAAGGAAGGAAGGAAAGAAGAGATGAGCTGGGTGTGGTCATGTGCACCTGTAGTCCTAGC TACTTGGGAGGCTGAGGCAGGAAGATCTCTTGAGCTCAGGCATTTGAGGCTGCAGTGAGCTAGGACTGCA CCACTGCACTCTAGCCCAGGTGGCAGGGCGGGACCCTGTCTCTGTTTTAGAAGAGAAAAAGATAACGACT AAGTGTCATGAAAAGATGTGAAGAAATACAATGAGATGCCCGAGTGAAGGCTCTGAAAACACCTGCTCGA GTTCGAATGTGTGCTCTGACACCTGACTCGTTAATGTCCTTGGCCAAGTAACTTTACCTGTCTGTGCCTC CCATGCCGATCCGTACATGGGGGATGATGACAGTAGTATCTGCCCCACGAGGGGTTGTTGAGAGGATGAA AGTGGGAGTAGGAGACCAGAAATGATGATCACAGAGATGCTGGTTATCTTGGTCAGGCCCCACTCAAGGG TAGCTGATAATTTTATGTCTTACACTGGAGATGACAGTGACCCATACACGCAGCACAGCACTGCATGAAA AGCTGGTGAGTCGATACAGAGAGTCATACTGAAGGTCTAAGGAGGGCTAGGGTAGCCTGTAGCAGAATGA GCGTGAAGGCTCTGCTGAAAGGGCATTGCTCCCTGGACCTGTGGCGGGATCCTCGGTAGAAAGCTGACAT TGAAAGATTTTGAAGAGCTTTAGTTAAAAAGTTAAAAACAGCCCAGCGCAGTGGCTGACGCCTGTGATCC CAGCACTTTGAGAGGCTGAGGCGAGTGGATCATGAGGTCAGGAGATTGAGACCATCCTGGCTAACACAGT GAAATCCCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCATGGTGGCGGGCGCCTGCAGTCCCAGCTA CTTGGGAGGCTGGGGCAGGAGAATCACTTGAACCCGGGAGGCGGAAGTTGCAGTGAGCCAAGATTGTGCC ACTGCACTCTAGCCTGGGCGACAGAGCAAGACTGTCCCCCCACCCAAAAAAAATAAATAAAAAATAAAAA TAAACCAATGTTGGCAAGGCTATGGAGTAAAGGGAACGCTTAGGAACGCTTATGCGCTGTTGGTGGGAAT GTAAACGAGTTCACCCACTGTGGGGCACACTTTGTAGATTTCTCAAAGAACTGAGAAAGCAACTAGCATT TGACCCAGCAATCCCACTGCTGGGTGTATACCCAAAGGAAAATAAATCGTTCAACGGCACTGCGCCCGTA TGTTCATTACCGCACTATCTGCAATAGCAAAGACACAGAATCAACCCAAGTGCTCATCAATGGTGACTTG GATAAAGAAATGTGGTGTATATATACTACGGAATACTACGCAGCCGTGAAAAGGAGGGAAATCATGTCCT TTGCAGCCACATGAGTGCAGCTGGAAACCATTATCCTAAGGGAACTAGTGCAAAAACAGAAAACCAAATA CCACATGTTCTCACTTAAAAGTGGGAGCTAAACATTGGGTACACATGGTCATAAAAATGTGAACAAGAGA CACTGGGGAATACAAGGAGGTGGGAGGGAGGAAGCAGGATAAGGGCTGAAAAAATTCTACCTATTGGGCG CTATGCCCACTACCTGGGCGATGGATCCGTTCATATGCCAAACCTCAGGGACACACAATATACCCATGTA ACAAATCTGCACATGGACTTCCTGTTTCTAAAAATCAACAAAGATTGTGAGACCTGCCCAGTGGCCAGCT GGCTGTGTATCTTCTCCACCAATGAGGCTGCATTACTTCATCCTCCTCTCCCTGGGAGGGGGAGCAGGGG TGAAGCTGTTAATGGCCACAGTGGCTGACTCACCTCATGGCGAGAGGAACCTCTCTCATCTGACTTCTTT CCCAGCCTTGGTCAGATGACTCCACATTGAATCTGGCATTTATTTCCCGAGGCAGGAACCTAGATCCAGT TTGCCTCGAGTCAGGATAGACCCTTTATCCAGGGGCTAACCAGAAATCACAGGGCACAGTGAACCACTCA GCTCTGGCTGGCTGTGGCCAGTGAGTGACCGCATGGCCTGAGCGGGCCACCTCCTCCTGGACCGATGACT CAGTCTCACGTGTCGAGTCGGGCACCAGGAGACTCATACAGAGTTGGCCCTGTAATTTTCTTCTACATTC CTCTTCTCCAAAAGGAAAAATAAACATACAACCCTTCGTTACAAATTTTAATTCCCGGTTTTCTGTAACC CAGACTCATGCCTCGCTTTTCTCGGAGACAGACATAAGTAGAACATCGCTGCAGATGCTCACGGTGTGTA CACCCAACCAAGTCTTAATCAGACCAGAGGCGGTCCTCTCTTCACATTTATACATGACAGCCACGTTCAT GTTAGCCCAATAACTAGGACCATTGAAAAGATACAATTTTTTGGCTGGGCGCAGTGGATCACTTGAAGTC AGGAGTTCAAGACCAGCCCAGCCAACATGGTGAAACCGTGTCTCTACTAAAAAATACAAAGATTAGCCAT GGGTGGTGGCGCATACCTGTAATCCCAATTTTTTGGGAGGCTAAGGCAGGAGAATGCTTGAACCTGGGAG GCAGAGGTTCCAGTGAGTCGAGATGGCACCGCTGCACTCCAGCCTCGGTGACAGAGCAAGACTCCGTCTC CAAAAAAAAAAAAAAGAAAAAATACAATTTTCACTTCATCTCTTCTTCCTGCCATTGCTTACCTCCTGAG GAAGCCAGAATTGGTGGTAAAAGGCCAAAAGAGAAGATGGCAGGAAAAGGCAGAATGTGAAGCATATCAT TAGAACAAGCACGGGTGTGTCTCATCAGTAAACTTATTGAGCAATTACTATGTGCAGGGAACTGTGGAAA CAAAAGGGTTAAGACACAGCCCTTACTCTCTATACGTACTCTCTGATTAAGGAGCGAGATGCAGAAGAAA GGCAAATCTAATAGAAAGTGGGAGTTAATGCTGGTCAAGTGATACATACAGTGGAAATCACCATAGAAGC TGGGAAGCCAGGATAGAGCTTCAGCCTGTCTGTAGTGGCAGGTGCCCAGGCTGGACAGGGAAGGGGCTGC GGTATACCTGTATGGGCGCCAAATGCCAGAATCAACCAGGATACAGGAATGGGTTCCTTTCCATCTGTCT GTTTTGCTCCTTCCTGATCTATTCTGAACTCACAGAAAATAGCTATAGGTCTAGTGGGGAAAGTTATATA TCTAATTTTGATTTTTTTTTTTTTTGAGACGGAGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAATGGCGC GATCTTGGCTCTTTGTAACTTCCACCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCT GGGATTACAGGCATGCACCACCACCCCCAGCTAATTCTTATATTTTTAGTAGAGACGGGGTTTCACCGTG TTGGCCAGGTTGGTCTCGAACTCCTGACCTCAAGTGATCTGCCCACCCTGGCCTCCTAAAGTGCTGGGAT TACAGGTGTGAGCCACCATGCCCAGCTAGTTTTGAATTGTTTAAGGCCACCCAAACATTTACCTTATGAA GTTATAGGATTTGGAATAAATGTTACAGGAGTAATTCTACTTTCTCATCCTGTTCCTCACCTGGAATGTC ACATAAGTCTAAACGGAGAAAAGGACCCGAAGATAAAGGAACAGCTAGAACAGGAAGTGCGAGCATAAGA ATTCAAACCCAGGGAGCTGGCACAATGAGTGCCCCGTGCCCAGGACAATGGAGGCCACTTGTGTCTGCTT GGAGCCCCAGGCAAGCCATCCACATTTCCATGGCACAGGGGTGCAGTCGATGAGCTGCATTAGTCCTTCG CTGGGCTGTGTTTCTATTAGTGGATCCTCTGAGGCTGGTGCTGTGCCTGAGATCATTAAGTCAGATGCGC TGAAACTTTGTCAAACAAAAGTGCTTAGGGCACAGCCTGAGGCTCTGTCTGCTTCTCAAGGAATTGCCCA TCAGTCTCTGCCAGGCGTGGGTGCTCATCACTGACACCTGTGTCTCTTCACAAGGGGCTGTTGTAGCAGG AGGGATGAGGTTTTTTTTGTTTTTGTTTTTGTTTTTTTTGTTTTGAAGACAGAGTCTTACTCTGTCACCC AGGCTGGAGTGCAGTGGCTTGATCTTGACTCACTGCAACCTCCACCTCCTGGGTTCAAGTGATTCTCCTG CCTCAGCCTCCTGAGTAGCTGGGACTACAGGCACCCGCCACCACACCCGGCTAATTTTTTGTATTTTTTT TATTTTATGTATTTATTTGAGATGGAGTTTTGCTCTTGTCACTGAGGCTGGAATGTAGTGGCATGACCTC TTCTCGCTGTAACCTCTGCCCACTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATT ACAGGTACCCACGACCATGCCCAGCTAATTTTTGTATGTGTAGTAGAGACGGGGTTTCACCATGTTGGCC AGACTAGTCGCAAATGCCTGACCTCGAGTGATGTCCCTACCTCAGCCTCCCAAAGTACTGGGATTACAGC CATGAGCCACCATGCCCTGCCTGAAAGATTAGTTTTTATTTTATTTATTTTTTATTTATTTTCTTTTTTG AGATGGAGTCTGTCTCTGTCGCCCAGGCTGGAGTGCAGTTTGCAATCTCGGCTCACTGCAACCTCCACCT CCCGGGTTCAAGCGATCCTCCTGCCTCAGTCTCCTGAGTAGCTGGGATTACAGGCATGCATCACCACGCC TGGCTATTTCTTTTTGTATTTTTAGTAGAGACGGGGTTTCGCCATGTTGGCCAGGCTGGTCTCGAACTCC TGACCTCAAGTGATCCGCCCACCTCAGCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCATCGCACCTG GCCTGAGGGATGAGTTTTTAAATGACTTCCATAGCTGTCATTAGGTTCTGTCAGCCACTGGAACACACTG CTTTGTTCTTTTCCTCCTGCTTGTAAAACGCCAAGGCTATTGCCAATGTAGTATCTTCAGCAAAGGAAGG AGGCAGCTGAGTCAGGAGCCGGAAGTACAGAAAGAAGCCACAGCTCATCATGCCTGATGAAGGGAATTCA GAGCAGATTCCTAATTTTCAAAAATTCCATGCTTTGGCTCTTCATAATGGAAAAATGCAGAATTATAAGT TTAAACTCAAATGGGAGAAGCACCTGTGAATTAATATTTTGTGAAAAACAAAACAGGAAACAATATAATC TACATACTGCATGACGTTTTATGTGTGAAGATGCACATAGAAGAGAATATTGGCCGGGCGCAGTGGCTCA CACCTGTAATCCCAGCACTTTGGGAAGTCAAGGTGGGAGGATCACTTAAGCTCAGTTCAAGACCAGCCTG GGCAACATGGTGAAACATCGTCTCTATCCTTTTTTTAGAATAAAATTTAATTTAAAAGAATATTGGGGCC AGGCGTGGTGGCTCATGCCTATAATCCTAACACTTTGGGAGGCCAAAGTGGGGGTATTGCTTGAGCGCAG AAGTTTAAGACCAGCCTGAGTAACATAGCAAGACCCTGTTTCTACAAAAAAAAATATAAAAAATTAGCAG GGTGTAGTGGTTCACACCTATAGTCCCAGCTATTCAGGAGACTGAGACGGGAGGATCGCTTGAGCTTGGG AGGTCAAGGCTGCAGTGAGCTATGATCATACCATTGCACTCTGGCCTGAGCGACAGAGCAAGACTGTCTC AAAATCAATAGTGGAATATTGGAAGGAAATACATCAAAATATTAGCTGTGGGTAATGAAAGTAGGGAATT TTTTTCTTTTCTTTTTTTTTTTTAGACTGAGTCTCGCTCTGTCGCCCAGGCCCAGGCTGGAGTGCAGTGG CACCAACTCGGCTCACTGCAACCTCCGCCTCCCGGGTTCACGCCATTCTCCTACCTCAGCCTCCTGAGTA GCTGGGACTACAGGTGCCCGCCAGCACGCCTGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGGTTTCA CCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTTGTGATCCACCTGCCGCGGCCTCCCAAAGTGCTGG GATTACAGGCATGAGCCACCGCCCCTGGCCAGGAAGTTTTTTCTTTGTTTCCAATGTTTAAGTTTCTGTC AGTGAACATGCATTATGGCTTTCTTTTTTTTTCCACTTTTTATTTTTTTGAGACGGAGTCTTGCTGTGTC ACCCAGGCTGGAGTTCAGTGGCGCGATCTCGGCTCACTGCAACTTCCGCCTCTGGGGTGCAAGAGCGATT CTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCGTGTGACACCACACCCGGCTAATTTTTTGTAT TTTAGTAGAGAGGGGGTTTCATCACGTTGGCCAGGCTGGTCTTGAACTCCTGGCCTCAAGAGATCCACCC GCCTCAGCCTCCCAAAGTGCTGGGATTACAGGAGTGAGCCACCGTGCCTGGCCACCCACTGTGTTTTAAC TCAGAATAGACAGTGCACAGGATTGTTGCAACGAAATCCCAGCGCCCCTGCGCCGGGTGGAGGAGCTGGG CAGGAGGAGGACTTTTCCCTCTCCCTGAGCTCGGTGATCCCCGTCTCTCCGCAGGAAAGGCCGAGGGGGA CGGCAAGATGCACATCACCCTCTGTGACTTCATCGTGCCCTGGGACACCCTGAGCACCACCCAGAAGAAG AGCCTGAACCACAGGTACCAGATGGGCTGCGAGTGCAAGGTAAGCAGGTCCTGCCTCTGCTGGAGCATCG CCTCCTCCCAGTGTCTCCAGATGGACGGCAGGGATTTTGATCCCTGGCTTTCCAGGACCCGTTAATCCCC GGCTCCTGATCTAAGACCAGGCTCTGGGAAGGTAGAGTCATCCCAAGAGTAAGGCTGTCTGGCTGGGGAC AGAGCCTTTGACCCCTGGTCCCTGGAGAGCCCTGAGGCACATCTCTGACAGGGGATGTCTGGAGGCCGGG CGCTGCGGCTCACGCCTGTAATCCCGGCACTTTGGGAGGCCGAGATAGGTGGGTCACTTGAGGTCGGGAG TTGGAAATCAGCCTCACCAACATGGCGAAACCCTGTCTCTACAAAAATACAAAAATTAGCCAGGTGAGGT GGTGCACGCCTGTGATCCCAGCAACTTGGGAGGATGAGGCTTAAGAATTGCTTGAATGTGGGAGGTGGAG GTTGCAGTGAGTTGAGATCACACCACTGCACCCCAGCCTGGGTTGACAGAGTGAGACTCTGTCCCAAAAA AAAAAGAGGGAGATGTCTGGAAGGCTAGGAGATTTGAGAGTAAGAGCATGAATTCAGCTCTGTTACCTGT AGCTTCCAGAAAAAGGAGCTGTATGGGGAGAGAGAATATGGTCCCATGGAGAATTTTCTACAAATGTGCA AGTGCAAACGCCTGTGTGGCTTATGAGAAGGCACTGCAGGCCTTACGCTGTTTCCAACATTCCCGACATT TTCACACCTGGGTTGGTGTCTATGTGGGGTCTGTGTGTTGAGAATACCTGAACACCTGCTCCTCTTAAAA TGAGCCCGGAGGTTGTGCCAGGCACAGCTGGAGCAGTGCAGCGCCTAGATGTGGCTGTGGAAGGTGAGAT TACCGCCTCCAGGGCTCCCAGGCTGGCTCCTACCCTGTGGGCTCCTAGCACCCTATCCCCACCCTCCCTG CAGGAAGCATGGCTGAGTGCTGGGCACCTCCCACCCTGGGTCACTCCCAGTGAGTCTGGGACCAGGAGAC TCTGGTGAGGCTGTGGGGATTGGCCTTCCCTGGGGAGCTGCCTGGGGCTGCCCTCCCTCCTGACGGCCCC CAGCCCCTTCTCCGCATGTTCAAAACAGGAATTCTGAACTCATAGTCTCCAGCCACACGTATGTTAAGCG AAACTCCTCTGTGCCCAGCATGAAATCAAAAGCAAGTTTTTCCTTTTTCTTTCCACGGTGGTGAAGGCGG TCATCCTCTTGTAGCCTAGGGTTCCTTGGCCAAATTGCTAGTTGCCGATGACCTCGGGGCTCGGCTTGCG AGCAACACTGGGCTGGAATCTGTCTCCAGGAAACCCAGGCCCTTTTATTGTTGCTGTGTCCCCCAGAGGG CAGGGCCAAGCTGAGGCCATTCTGTCATGCTCAGGAAGGTAGAAGATGGCCCAAAGGGAAGCACACCTGC AGTAGGAGGGGGGGCAGCGGTGGGCAGGGCACAGCTTCCCTGCAGGTTAGACCCCCTCGCAGGCCAGCTG CCTGCCCCTGCAGGAACCGTGGGTCTCGGGAGAGGCTGCCATCCCTGCACATGACAGGTAGGCACATTGC CGGGTTCTGGACATGCCCCCAGAGCAGCCTCTGCCCACCCCTTCCTGGGTCCCTGACTCCGTCCCCCTCC GTGTGCCCCTCCCCAGATCACGCGCTGCCCCATGATCCCGTGCTACATCTCCTCCCCGGACGAGTGCCTC TGGATGGACTGGGTCACAGAGAAGAACATCAACGGGCACCAGGCCAAGTTCTTCGCCTGCATCAAGAGAA GTGACGGCTCCTGTGCGTGGTACCGCGGCGCGGCGCCCCCCAAGCAGGAGTTTCTCGACATCGAGGACCC ATAAGCAGGCCTCCAACGCCCCTGTGGCCAACTGCAAAAAAAGCCTCCAAGGGTTTCGACTGGTCCAGCT CTGACATCCCTTCCTGGAAACAGCATGAATAAAACACTCATCCCATGGGTCCAAATTAATATGATTCTGC TCCCCCCTTCTCCTTTTAGACATGGTTGTGGGTCTGGAGGGAGACGTGGGTCCAAGGTCCTCATCCCATC CTCCCTCTGCCAGGCACTATGTGTCTGGGGCTTCGATCCTTGGGTGCAGGCAGGGCTGGGACACGCGGCT TCCCTCCCAGTCCCTGCCTTGGCACCGTCACAGATGCCAAGCAGGCAGCACTTAGGGATCTCCCAGCTGG GTTAGGGCAGGGCCTGGAAATGTGCATTTTGCAGAAACTTTTGAGGGTCGTTGCAAGACTGTGTAGCAGG CCTACCAGGTCCCTTTCATCTTGAGAGGGACATGGCCCTTGTTTTCTGCAGCTTCCACGCCTCTGCACTC CCTGCCCCTGGCAAGTGCTCCCATCGCCCCGGTGCCCACCATGAGCTCCCAGCACCTGACTCCCCCCACA TCCAAGGGCAGCCTGGAACCAGTGGCTAGTTCTTGAAGGAGCCCCATCAATCCTATTAATCCTCAGAATT CCAGTGGGAGCCTCCCTCTGAGCCTTGTAGAAATGGGAGCGAGAAACCCCAGCTGAGCTGCGTTCCAGCC TCAGCTGAGTCTTTTTGGTCTGCACCCACCCCCCCACCCCCCCCCCCCCGCCCACATGCTCCCCAGCTTG CAGGAGGAATCGGTGAGGTCCTGTCCTGAGGCTGCTGTCCGGGGCCGGTGGCTGCCCTCAAGGTCCCTTC CCTAGCTGCTGCGGTTGCCATTGCTTCTTGCCTGTTCTGGCATCAGGCACCTGGATTGAGTTGCACAGCT TTGCTTTATCCGGGCTTGTGTGCAGGGCCCGGCTGGGCTCCCCATCTGCACATCCTGAGGACAGAAAAAG CTGGGTCTTGCTGTGCCCTCCCAGGCTTAGTGTTCCCTCCCTCAAAGACTGACAGCCATCGTTCTGCACG GGGCTTTCTGCATGTGACGCCAGCTAAGCATAGTAAGAAGTCCAGCCTAGGAAGGGAAGGATTTTGGAGG TAGGTGGCTTTGGTGACACACTCACTTCTTTCTCAGCCTCCAGGACACTATGGCCTGTTTTAAGAGACAT CTTATTTTTCTAAAGGTGAATTCTCAGATGATAGGTGAACCTGAGTTGCAGATATACCAACTTCTGCTTG TATTTCTTAAATGACAAAGATTACCTAGCTAAGAAACTTCCTAGGGAACTAGGGAACCTATGTGTTCCCT CAGTGTGGTTTCCTGAAGCCAGTGATATGGGGGTTAGGATAGGAAGAACTTTCTCGGTAATGATAAGGAG AATCTCTTGTTTCCTCCCACCTGTGTTGTAAAGATAAACTGACGATATACAGGCACATTATGTAAACATA CACACGCAATGAAACCGAAGCTTGGCGGCCTGGGCGTGGTCTTGCAAAATGCTTCCAAAGCCACCTTAGC CTGTTCTATTCAGCGGCAACCCCAAAGCACCTGTTAAGACTCCTGACCCCCAAGTGGCATGCAGCCCCCA TGCCCACCGGGACCTGGTCAGCACAGATCTTGATGACTTCCCTTTCTAGGGCAGACTGGGAGGGTATCCA GGAATCGGCCCCTGCCCCACGGGCGTTTTCATGCTGTACAGTGACCTAAAGTTGGTAAGATGTCATAATG GACCAGTCCATGTGATTTCAGTATATACAACTCCACCAGACCCCTCCAACCCATATAACACCCCACCCCT GTTCGCTTCCTGTATGGTGATATCATATGTAACATTTACTCCTGTTTCTGCTGATTGTTTTTTTAATGTT TTGGTTTGTTTTTGACATCAGCTGTAATCATTCCTGTGCTGTGTTTTTTATTACCCTTGGTAGGTATTAG ACTTGCACTTTTTTAAAAAAAGGTTTCTGCATCGTGGAAGCATTTGACCCAGAGTGGAACGCGTGGCCTA TGCAGGTGGATTCCTTCAGGTCTTTCCTTTGGTTCTTTGAGCATCTTTGCTTTCATTCGTCTCCCGTCTT TGGTTCTCCAGTTCAAATTATTGCAAAGTAAAGGATCTTTGAGTAGGTTCGGTCTGAAAGGTGTGGCCTT TATATTTGATCCACACACGTTGGTCTTTTAACCGTGCTGAGCAGAAAACAAAACAGGTTAAGAAGAGCCG GGTGGCAGCTGACAGAGGAAGCCGCTCAAATACCTTCACAATAAATAGTGGCAATATATATATAGTTTAA GAAGGCTCTCCATTTGGCATCGTTTAATTTATATGTTATGTTCTAAGCACAGCTCTCTTCTCCTATTTTC ATCCTGCAAGCAACTCAAAATATTTAAAATAAAGTTTACATTGTAGTTATTTTCAAATCTTTGCTTGATA AGTATTAAGAAATATTGGACTTGCTGCCGTAATTTAAAGCTCTGTTGATTTTGTTTCCGTTTGGATTTTT GGGGGAGGGGAGCACTGTGTTTATGCTGGAATATGAAGTCTGAGACCTTCCGGTGCTGGGAACACACAAG AGTTGTTGAAAGTTGACAAGCAGACTGCGCATGTCTCTGATGCTTTGTATCATTCTTGAGCAATCGCTCG GTCCGTGGACAATAAACAGTATTATCAAAGAGAA Download Select all
Length	72414
OMIM ID	188825
HGNC ID	HGNC:11821
Unigene ID	Hs.633514
Ensembl ID	ENSG00000035862
PharmGKB ID	-

mRNA Information

mRNA ID	NM_003255.4
Exon	join(1..432,51472..51572,54385..54493,67745..67869, 69527..72414)
mRNA Sequence	>7077 CGCAGCAAACACATCCGTAGAAGGCAGCGCGGCCGCCGAGAACCGCAGCGCCGCTCGCCCGCCG CCCCCCACCCCGCCGCCCCGCCCGGCGAATTGCGCCCCGCGCCCCTCCCCTCGCGCCCCCGAGA CAAAGAGGAGAGAAAGTTTGCGCGGCCGAGCGGGGCAGGTGAGGAGGGTGAGCCGCGCGGGAGG GGCCCGCCTCGGCCCCGGCTCAGCCCCCGCCCGCGCCCCCAGCCCGCCGCCGCGAGCAGCGCCC GGACCCCCCAGCGGCGGCCCCCGCCCGCCCAGCCCCCCGGCCCGCCATGGGCGCCGCGGCCCGC ACCCTGCGGCTGGCGCTCGGCCTCCTGCTGCTGGCGACGCTGCTTCGCCCGGCCGACGCCTGCA GCTGCTCCCCGGTGCACCCGCAACAGGCGTTTTGCAATGCAGATGTAGTGATCAGGGCCAAAGC GGTCAGTGAGAAGGAAGTGGACTCTGGAAACGACATTTATGGCAACCCTATCAAGAGGATCCAG TATGAGATCAAGCAGATAAAGATGTTCAAAGGGCCTGAGAAGGATATAGAGTTTATCTACACGG CCCCCTCCTCGGCAGTGTGTGGGGTCTCGCTGGACGTTGGAGGAAAGAAGGAATATCTCATTGC AGGAAAGGCCGAGGGGGACGGCAAGATGCACATCACCCTCTGTGACTTCATCGTGCCCTGGGAC ACCCTGAGCACCACCCAGAAGAAGAGCCTGAACCACAGGTACCAGATGGGCTGCGAGTGCAAGA TCACGCGCTGCCCCATGATCCCGTGCTACATCTCCTCCCCGGACGAGTGCCTCTGGATGGACTG GGTCACAGAGAAGAACATCAACGGGCACCAGGCCAAGTTCTTCGCCTGCATCAAGAGAAGTGAC GGCTCCTGTGCGTGGTACCGCGGCGCGGCGCCCCCCAAGCAGGAGTTTCTCGACATCGAGGACC CATAAGCAGGCCTCCAACGCCCCTGTGGCCAACTGCAAAAAAAGCCTCCAAGGGTTTCGACTGG TCCAGCTCTGACATCCCTTCCTGGAAACAGCATGAATAAAACACTCATCCCATGGGTCCAAATT AATATGATTCTGCTCCCCCCTTCTCCTTTTAGACATGGTTGTGGGTCTGGAGGGAGACGTGGGT CCAAGGTCCTCATCCCATCCTCCCTCTGCCAGGCACTATGTGTCTGGGGCTTCGATCCTTGGGT GCAGGCAGGGCTGGGACACGCGGCTTCCCTCCCAGTCCCTGCCTTGGCACCGTCACAGATGCCA AGCAGGCAGCACTTAGGGATCTCCCAGCTGGGTTAGGGCAGGGCCTGGAAATGTGCATTTTGCA GAAACTTTTGAGGGTCGTTGCAAGACTGTGTAGCAGGCCTACCAGGTCCCTTTCATCTTGAGAG GGACATGGCCCTTGTTTTCTGCAGCTTCCACGCCTCTGCACTCCCTGCCCCTGGCAAGTGCTCC CATCGCCCCGGTGCCCACCATGAGCTCCCAGCACCTGACTCCCCCCACATCCAAGGGCAGCCTG GAACCAGTGGCTAGTTCTTGAAGGAGCCCCATCAATCCTATTAATCCTCAGAATTCCAGTGGGA GCCTCCCTCTGAGCCTTGTAGAAATGGGAGCGAGAAACCCCAGCTGAGCTGCGTTCCAGCCTCA GCTGAGTCTTTTTGGTCTGCACCCACCCCCCCACCCCCCCCCCCCCGCCCACATGCTCCCCAGC TTGCAGGAGGAATCGGTGAGGTCCTGTCCTGAGGCTGCTGTCCGGGGCCGGTGGCTGCCCTCAA GGTCCCTTCCCTAGCTGCTGCGGTTGCCATTGCTTCTTGCCTGTTCTGGCATCAGGCACCTGGA TTGAGTTGCACAGCTTTGCTTTATCCGGGCTTGTGTGCAGGGCCCGGCTGGGCTCCCCATCTGC ACATCCTGAGGACAGAAAAAGCTGGGTCTTGCTGTGCCCTCCCAGGCTTAGTGTTCCCTCCCTC AAAGACTGACAGCCATCGTTCTGCACGGGGCTTTCTGCATGTGACGCCAGCTAAGCATAGTAAG AAGTCCAGCCTAGGAAGGGAAGGATTTTGGAGGTAGGTGGCTTTGGTGACACACTCACTTCTTT CTCAGCCTCCAGGACACTATGGCCTGTTTTAAGAGACATCTTATTTTTCTAAAGGTGAATTCTC AGATGATAGGTGAACCTGAGTTGCAGATATACCAACTTCTGCTTGTATTTCTTAAATGACAAAG ATTACCTAGCTAAGAAACTTCCTAGGGAACTAGGGAACCTATGTGTTCCCTCAGTGTGGTTTCC TGAAGCCAGTGATATGGGGGTTAGGATAGGAAGAACTTTCTCGGTAATGATAAGGAGAATCTCT TGTTTCCTCCCACCTGTGTTGTAAAGATAAACTGACGATATACAGGCACATTATGTAAACATAC ACACGCAATGAAACCGAAGCTTGGCGGCCTGGGCGTGGTCTTGCAAAATGCTTCCAAAGCCACC TTAGCCTGTTCTATTCAGCGGCAACCCCAAAGCACCTGTTAAGACTCCTGACCCCCAAGTGGCA TGCAGCCCCCATGCCCACCGGGACCTGGTCAGCACAGATCTTGATGACTTCCCTTTCTAGGGCA GACTGGGAGGGTATCCAGGAATCGGCCCCTGCCCCACGGGCGTTTTCATGCTGTACAGTGACCT AAAGTTGGTAAGATGTCATAATGGACCAGTCCATGTGATTTCAGTATATACAACTCCACCAGAC CCCTCCAACCCATATAACACCCCACCCCTGTTCGCTTCCTGTATGGTGATATCATATGTAACAT TTACTCCTGTTTCTGCTGATTGTTTTTTTAATGTTTTGGTTTGTTTTTGACATCAGCTGTAATC ATTCCTGTGCTGTGTTTTTTATTACCCTTGGTAGGTATTAGACTTGCACTTTTTTAAAAAAAGG TTTCTGCATCGTGGAAGCATTTGACCCAGAGTGGAACGCGTGGCCTATGCAGGTGGATTCCTTC AGGTCTTTCCTTTGGTTCTTTGAGCATCTTTGCTTTCATTCGTCTCCCGTCTTTGGTTCTCCAG TTCAAATTATTGCAAAGTAAAGGATCTTTGAGTAGGTTCGGTCTGAAAGGTGTGGCCTTTATAT TTGATCCACACACGTTGGTCTTTTAACCGTGCTGAGCAGAAAACAAAACAGGTTAAGAAGAGCC GGGTGGCAGCTGACAGAGGAAGCCGCTCAAATACCTTCACAATAAATAGTGGCAATATATATAT AGTTTAAGAAGGCTCTCCATTTGGCATCGTTTAATTTATATGTTATGTTCTAAGCACAGCTCTC TTCTCCTATTTTCATCCTGCAAGCAACTCAAAATATTTAAAATAAAGTTTACATTGTAGTTATT TTCAAATCTTTGCTTGATAAGTATTAAGAAATATTGGACTTGCTGCCGTAATTTAAAGCTCTGT TGATTTTGTTTCCGTTTGGATTTTTGGGGGAGGGGAGCACTGTGTTTATGCTGGAATATGAAGT CTGAGACCTTCCGGTGCTGGGAACACACAAGAGTTGTTGAAAGTTGACAAGCAGACTGCGCATG TCTCTGATGCTTTGTATCATTCTTGAGCAATCGCTCGGTCCGTGGACAATAAACAGTATTATCA AAGAGAAAAAAAAAAAAAAAAA Download Select all
Length	3670

CDS Information

Location	join(303..432,51472..51572,54385..54493,67745..67869, 69527..69724)
CDS Sequence	>lcl\|NM_003255.4_cds_NP_003246.1_1 [gene=TIMP2] [protein=metalloproteinase inhibitor 2 precursor] [protein_id=NP_003246.1] [location=303..965] ATGGGCGCCGCGGCCCGCACCCTGCGGCTGGCGCTCGGCCTCCTGCTGCTGGCGACGCTGCTTCGCCCGG CCGACGCCTGCAGCTGCTCCCCGGTGCACCCGCAACAGGCGTTTTGCAATGCAGATGTAGTGATCAGGGC CAAAGCGGTCAGTGAGAAGGAAGTGGACTCTGGAAACGACATTTATGGCAACCCTATCAAGAGGATCCAG TATGAGATCAAGCAGATAAAGATGTTCAAAGGGCCTGAGAAGGATATAGAGTTTATCTACACGGCCCCCT CCTCGGCAGTGTGTGGGGTCTCGCTGGACGTTGGAGGAAAGAAGGAATATCTCATTGCAGGAAAGGCCGA GGGGGACGGCAAGATGCACATCACCCTCTGTGACTTCATCGTGCCCTGGGACACCCTGAGCACCACCCAG AAGAAGAGCCTGAACCACAGGTACCAGATGGGCTGCGAGTGCAAGATCACGCGCTGCCCCATGATCCCGT GCTACATCTCCTCCCCGGACGAGTGCCTCTGGATGGACTGGGTCACAGAGAAGAACATCAACGGGCACCA GGCCAAGTTCTTCGCCTGCATCAAGAGAAGTGACGGCTCCTGTGCGTGGTACCGCGGCGCGGCGCCCCCC AAGCAGGAGTTTCTCGACATCGAGGACCCATAA Download Select all
CCDS ID	CCDS11758.1

Protein Information

Protein ID	NP_003246.1
Protein Name	TIMP metallopeptidase inhibitor 2
Molecular Wt. (Da)	21755
Protein Sequence	>7077 MGAAARTLRLALGLLLLATLLRPADACSCSPVHPQQAFCNADVVIRAKAVSEKEVDSGNDIYGN PIKRIQYEIKQIKMFKGPEKDIEFIYTAPSSAVCGVSLDVGGKKEYLIAGKAEGDGKMHITLCD FIVPWDTLSTTQKKSLNHRYQMGCECKITRCPMIPCYISSPDECLWMDWVTEKNINGHQAKFFA CIKRSDGSCAWYRGAAPPKQEFLDIEDP Download Select all
Length	220
Uniprot ID	Q16270
Ensembl Protein ID	ENSP00000295666

Post-translational Modification Information (Source : HPRD)

No matching records could be found.

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
3688	ITGB1	628	NP_391987.1	in vivo	16326706
4313	MMP2	386	NP_004521.1	in vitro;yeast 2-hybrid	1 237 478 910 991 940 000 000 000 000 000
4317	MMP8	385	NP_002415.1	in vitro	10353844

Pathway Information

No matching records could be found.

Structure Information

PDB ID	1BR9
Resolution	2.1
Method	?? X-RAY DIFFRACTION
Chains	A
Molecule	METALLOPROTEINASE-2 INHIBITOR
Model	View

Domain Information

ID	Location	Description
cd03585	27-209	NTR_TIMP
cl02512	27-209	NTR_like superfamily
smart00206	27-203	NTR
pfam00965	25-203	TIMP
cd03577	27-151	NTR_TIMP_like
cd03523	36-146	NTR_like

Ontology Information

HPRD ID	2839
Molecular Class	Extracellular matrix protein
Molecular Function	Receptor binding (GO:0005102)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO

CoReCG

Search results:

General Information

Evidence Information

Gene Details

mRNA Information

CDS Information

Protein Information

Post-translational Modification Information (Source : HPRD)

Enzyme Information

PPi Information

Pathway Information

Structure Information

Domain Information

Ontology Information

SNP Information

Drug Information

External Links

Important Information