Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| TM4SF4 | 7104 | transmembrane 4 L six family member 4 | 3 | il-TMP |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22011044 | 2012 | Cell line : - Source : Department of Surgery at Fooyin University Hospital for elective surgery. Sample Type : - No. of Sample : - Stage : - | Total RNA extraction and first-strand cDNA synthesis,Oligonucleotide microarray analysis,Design of oligonucleotide probes and EnCA preparation | Up-regulation | - | These results suggest that S100B, TM4SF3, and OLFM4 overexpression may affect metastatic behavior of tumor cells in Taiwanese CRC patients. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that can regulate cell proliferation.[provided by RefSeq, Mar 2011] |
| Chromosome | 3 |
| Location | 3q25 |
| Start | 149192368 |
| End | 149221181 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 28814 |
| OMIM ID | 606567 |
| HGNC ID | HGNC:11856 |
| Unigene ID | Hs.133527 |
| Ensembl ID | ENSG00000169903 |
| PharmGKB ID | PA36557 |
mRNA Information
| mRNA ID | ?NM_004617.3 |
|---|---|
| Exon | join(1..471,1243..1332,13039..13175,24142..24331, 28096..28814) | mRNA Sequence | Download Select all |
| Length | 1624 |
Protein Information
| Protein ID | NP_004608.1 |
|---|---|
| Protein Name | transmembrane 4 L six family member 4 |
| Molecular Wt. (Da) | 174255 |
| Protein Sequence | Download Select all |
| Length | 202 |
| Uniprot ID | Q14145 |
| Ensembl Protein ID | ENSP00000171111 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam05805 | 1-186 | L6_membrane |
| cl05399 | 1-186 | L6_membrane superfamily |
Ontology Information
| HPRD ID | 5866 |
|---|---|
| Molecular Class | Integral membrane protein |
| Molecular Function | Receptor signaling complex scaffold activity (GO:0030159) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.