CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
TSC1	7248	Tuberous sclerosis 1	9	LAM; TSC

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
20622004	2010	Cell line : - Source : - Sample Type : Case control study No. of Sample : 871 male and 685 female colon cancer cases and 1047 male and 909 female controls, 451 male and 303 female rectal cancer cases and 541 and 418 corresponding controls Stage : -	-	Polymorhpism	-	PIK3CA, PRKAG2, PTEN, STK11 and TSC1 were significantly associated with rectal cancer overall. The rs13295634 tagSNP of TSC1 was associated with a significant 40% reduction in the odds of rectal cancer.

Gene Details

Chromosome: 9; NC_000009.11 (135766735..135820020, complement)
View Larger Image

Gene Type	protein coding
Gene Family	-
Description	This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2009]
Chromosome	9
Location	9q34
Start	132891348
End	132945370
Strand	+
Gene Sequence	>gi\|568815589:c132945370-132891348 Homo sapiens chromosome 9, GRCh38.p2 Primary Assembly GTTCTGATTTTCAAGCTGTCTCCTATTAGGGCTGGTTTCCCCTAGATGTCATGAGTAGGTGTGAAGTGTG AGCTACTTGAAGGCAGAAGCCAGGGGGGTCCCCCGCAATCCCGGAGGCGGGCTTCTGAAAATGTTTAGCC CAGGAAGGAGGGCTGCCCTGGCCCGCAGCTTTCCGCCCCTTCCCAGGTGAGCTGCAACTCCAAAGCTCCC AAGCAGGCCCTTCACCCACGCGGGCCCCAGCAGCTCCTTGGGAAACAGGATCGCTGCTCTGAGGCCGCCC ACAGAGAGACCCTCGGAGGGCGCCACGCAAGCGAAGGGCAGAAACGACTCGGGGGGCAGGGGCAGGGCGC TCCAACCACACCCAGGCGCCGCCAGCTTGTTTACGCCTCTCCGCCGCGTCCCCCCGCCCGCCAGTCACGT GACCGCCCGCCCCGCCCCCTCGGGCTCTCGCGTGGCTCCTCCCGCCGCGCCGGCCCTTCTTTTTGCCTCC TTCGCGGAGTCACAAGATCTCTTCGCAGCCTCCTTTCGGATCCTTCCGCCCGGCCCCGCCCCCCTCCATA AAAACCCTCCTTACTTTTTTTCTCGTCCAACCCACATCGTCAGTTATGAGTGGAAGAGCCTCTTCCTTCC GGCGGGGCTGCCGAGCGCGGCCGTCTATCCTTCCTTTCGAGAAGGAGGGGAGGTCCGGAGGGGGACTCTT TTTCGTGGCGGAGGCCGCCGTCGGCCTTGGCCCTTTCACGACGGGGGAGGTGCTGTACGTCCAAGATGGC GGCGCCCTGTAGGCTGGAGGGACTGTGAGGTAAACAGCTGAGGGGGAGGAGACGGTGGGTGAGTATGGGG GTGTCTCCCCCTCCTTTTTATGGGGGCTTCCTGGGGCAGCCCCGGCACCATGACTCCAGCCGGGGAGGCT CGGAGGGGCTGGAGCAAGAGACTCACTTGCTTGGTAGGGATCCCGGGGAAGGGGGGTTCGGAGAGCTCTC CCCTCCCTCTTATTACACGCTATCTCCGGCTGGCCCGGCCGGGACTGGCGGGTCCCTGGGGAGGAGAGGC GAGCCGGACGGAGCACTTCGCCCCTCCTTGGCCCCCGAGGGGACGGCTGCACCCTGGGCCTCGGTCCCTC GGGCAGGGGCGAGGTGGGCCCCTTCGTCAGTCCCTCACTTGGTGGGGTGACAGGTTCACGCTAGGTGCGG AGGGCAGGGTAGAGACGCTTGGCGGGAGGGGAAGGGTCGCGAGGGTGGGGCTGGTCCCAGAACTTAAAGA GAGGGGTCGGGGTATAGGGGCGTGGAGAATGAATGGAGGTCGCCTGTGGGGATCAAGGACTCGCCTGGAT TCGGTGTCTCCGCTGAAATTTGCATGACTCGCTCTGGGTGTACTTGTGGGTGTTTAATTGGTGGTGAAAG ACAGTTACCTTAAAGTGGGCAAAGGGGATTCCTAAGAGACAGCTATTTGCAGAGCCCCTCCTAGGCGTTC ATTCATTCATTTGAGGAACTGGAGGATGAAGAGCCTGCAATCGGAGGGACCTTGTAGAATTAAAGCTCTT TCTTTGTGTTTCCTGTTAAAGAGTTTTGCTTTGTGTGTTTTGGATGTGTGGTGAGGACTTGGGAGGGGAC GCGGTCCTCCTAAGAACAACAGCTAACGTTAATGGAGTGCTCTCTGTGTGCCAGGCACTGTGAAAGTGCT TGGCAGTCATTATCTCCTTTGGTCCTCACGACAAAGAGAAGAGGCAGCCACTGTTAACACCTCCAATCTT CTCAAATGAAGAAACTGAGGCCCGGAGAGAGCAGGGTACTTTGCCTAAGTTCACACCCCAATTGTATCTG AGCCAGGACTGGAACTGCTGGGATCTGACTGACTCCAAAGATATGACTCTTAAATTTATCTGTTATTTGA TCAAAGCTGGCCTGTAAGTGATTAAAATTTATCATTTAGCCAAGGTTTATGCACGTGTGTCTGTTTAATG TTGAAGTGGGGGGATGCACTTGGCTTATCCGCCTTAGCTTTTGTTTGGGATGGCAGTGTTGTGCATGTGA ACTTGTTAGTCTAAATTAGGCTAAAAAGTATTTGATAGTTTAATAAAACTGATGAGTTTACTGAAGAAAG AAGTCCTGCTAAAATCCTTGCTGGCTTTTTTTTTTTTTTAAATAGAAAGCATACAAATAACACTTCACGT TGCATAGAGTAAGCTATAAAAGTGCTAAAATAGAATAATACTCTTCTGAGATACTTTGATTTATAATTTT GGGATCAACTTGGAGTCATCTGAATTCAAACAGGCCGGCAAAGTGGAGCTGTAAATTTCAGGAAGCATTA TAAAACCTAATCTTTGGGGAGCCTTTGATTTACCGAGCAACCACCTGTGATTCTTAAATTGAACATTCCT GAGTAAATCTGGAATATGCAAATGTGAAAACTGATTTAGGGTTGTGTAGGGAAATGCACCTTTAACAGTC ATGCATCAGGCAAATGAGGCTCCTCAGAAACAGTGAAACATTCTTTGCTATTGCCCTAGGGAGCTGCAGA ATCTTCCTCTAACCACCTGGTGTAAACTTAAGGGGTATTTATAGAAGATGTAAACGGAAAATATCCTCTT ACTAAAGTTAATATCTTATCCAAAACACTCTTATATCACGTGCCTAGAAGGGCAGATGATGTAAACTTTC TCTGCTGCATGCATTTCCTGGTGTCATAAACACTTGGTACGTTCCTAAATTCCTGGTTAGAAAGCAGGTG GCTACCAGCCTTCTTGTTTCCATAAAATTAGAGTGCTTCAGGTCCTGTGACTCAGTTGTCCTCTTCCTCA CTGGGTTAAGAGTAAAAACTGATACTGCTACTGTTGTGGTGTAATATGATGCCTTCTGTGCATGCCTGGT TTCATTCGTGAGATGAAACTTAACAGTCTTACTAGGGCAAATCTAATATATACCTCTATATGTAATGTTT GCAGAATAATGAACTTGGTGGAAACGAGATCTGAAACCCTAGTGCTCATGAGAACCTTGATGTACAGATA TTTGGCACTATACTAGGTAGACCTACATATTCGGACACCTTGTATATATATTTTGGAAGAAGACTGATTC TTATGTGCACCGGAGGTTGAGGACCACTGGCTTCAAGTATCATTCTGGCTATTTTCATTTATTATTTATC ACAGAGGTATTTCTTAAAATAGCTTGTAGCCTTTTATTTGTGTAGTGGTGGGTGAATTTTGGGCTCTGAA TTAGAGCTGACTTGTTCTTATAGCTCTGTCTTCATTTGAAGTTTGTTTGGCTACAGGTATGTTTATTTCT GGGTTCCAGGGCCATAGTGAACTAAAATTAGCTTTTCCTGGAATTAATTGGATATTCTTGAATGCCGATG AGCCAAATATAGCAATATCTCAACCATTTCAGGCTTTTCTAGAGAGTCAGATAGCTTTTGACCTTCAGTG GGTCACTTAAGTTCTGTGAGCCTGTGTCTTCATCTGTGAAGTAAAAGTTGGAATGTAAATTAATGAGTAT TTCTAGGCCTACATTTCTGTGATTTAAAGTCCTTTGGGGTGTCATTTAAATATTCTGACTAAATCGATTG AGTCAACCTGTTAATGGTTTTATAAAAACCAAGCAAATTGGTGACTTTGAGCCTACCCTGTTGGGTGAAG ATCTGTTTATCATTTATCCTTTCCTTTACATCATAATACTCTTTGAAAAGGTAATTCCCTATAAGTTTCC CATATTATAAATCTCTGAAAGGTTAGTCTTTGCATTGGTTTTGTCATTTAAGTAGCTGAAGGCGTGAAAG AAAAGTGTACTTAATAGCGTTAAAATCTGTGGCTGTTTGCTTGAAATGTGTATATGTAGTATACACTCAA ACACTGAGTTTGTTTTTTTTAATCTCAGATCATGAATTGGTAACTAATATAATTTGGGTAGCATGAAATA CTCATTCTCCATTTAAATTCATCTGAAAGAGGTAAACTGTCAGCAGTTTGAGATTATTCTTTCTCTGGTT TACTTTTTAAGACTGTAGTTGCTAGAAATTAGTAACTTTATGTCTGTTTTCATGGGAGAGAATAAAAATG CAAATTTTATATACTGTGTATAAAATACACTGTCTCAGGACCTTGTCAGTTTCTTCTTGTCCTTTCTCTC GTTCAGTGCTAACTTTTATTATGAACATGGAATCAGCAAAAGATAACAATACTTTTTACGGTTGAATGAA TTCAGATTTACATCTAATAAGTAAAATGTCTTAAAAACCATGCTTTAGTCCAAAATAAAGCATAGTAGTT ACTGCCCTACAACTCACAGGTCACTCTCTTAAGTAAATATGATGGCAGTAGAGGCCCAGAAGTGTTGGAG TAACAAAGGACAGTTTTGCCCTTCTGTGGGTGATGTGATGGAAGACACAGAGGGGAGCTGTAGGAAGAAC AGAGGCAGTGACCTTAATGTCTGCAATCATTAAGACTCTGCTACTTTGAGTAGTTCACAGAGCATAGTAA CAAACTTGAACTGTATCCATTTTAAGTTATACAATGGTTGTATCAATGTTTCAAATACCAGTTGTTAAAT GGATAGACTGCTAAGCATTATGTACCCAGCAATCCATTTTTGTGAAGTAGTAATATTGTTATAATAAAGT TTATATTTTTTGAGTACTCATGTGCCAAACACTGTGGTATTTTACATGTCTGATACCCCATTAACTTCTT ACAGCCTTAAGAGGCAGGATAGGAAGAGGAAGCAGGCTTAGAGTAAGTTGCCTATAGTCACTTATTCAGT GGCTAAGCTGGGATATGAACCTTTTTGGTTGACTCCACAGCCCAAACATTTAGTCTTCCACTGTGATAAA CTGCTTCATCTGCTGACCTCATAAATTAACTCACAGGTCAGGTCAGTGGTTCTTAACTTTGGTGGTGGTG GGAAGGTGTGTGGACTCAGTTGCCCTCTGAAAATCTGTGGGAAGCTATGGACCAAATTTCTCTTCTACCC TTTATGTCCCATCATCACCAAAAAAATTCATACAGACATGGGATTTTGGATATGGCTTCAGGTAATTTAT GGACGCAGCTTGAAACCCAGCTGATCATTTTAGATAGATTACTGCTCTAAAAATGGACTTAGGCTTTATT AAAAAACTTTTTTTTTTTTTTAACTAGTAGTCAGGAAAGGCCCAAGTCAGAAGGTGGCCTTATGTACTGT CTGGGTTATAAATTACTTTGTTAAATTTCTGTAGTGTACCCAGGTATGTAACCTGCTACGTGCTTGTCAG GCTTGGCATTCGGTCTGTGCTGGTACCTTTAGCACCTGGCAGAATTCCACTGGGCCTTTTCCCCAAGGTT TATGCACTCTATATATTTTTTTCCTTTTGAACCTCAAAGGAGGTATATTAATGAATGAATGTTTTTTACC TTCATCCTTCTTTTTCCTAGACCAGTGGTTCTGAACCTTTAGTGGACGTCAGAATTACCTAGAAGGCCCC ACCCCCAAAGTATCCAATTCCGAGATCTAGTGAAAGGCCTGAGAATTTACATTTCTAACAAATACCCAGG CTCCTGCTCGTGGTGCCAGGACCACATTTTGAGAACCACTGCCCTAGACTATCAAACTATACCCTTCTTC CCTAGAATACTTCTATTTTGGTCCTATAAACCTGAAACCTAAAGATATCTCACAGTTTGCTTGTATCTCT TTTAGGAGAAGCTCTGCGTAGTGTCTTTTTGAAATATACATGGTATCTGTTTGGCCTGTATTATCTTAGT AAATAATGTTGTTCATGTTAATAGAAAGTCAAAACGTAAGCATTATTTATTGAAGAGATACGCCTTACCA AAATTAAGCTCTGGCCTTACACTTAAGTTACTAGAAGATTCTTCACCTTTGGGATAGGCTATAAGCTTTA GCAAACCATCCATCAAGGCCCCTGATGGCAGAAATTCTGAATGGAGAATCTGGCAAGTTGGAGCTCTCCT GCCCCAGTTTGTCCTTGAGAGGGACTCCAACTACTAAGACCTATTCAATCACACATGACTACACATGTTG GCAGGTTTTACCATCAGCTGTTTTACTCTCACATAGTAAGTAGTTATTTCCTACCCTTTTTTCCTTCCTT CTAGGCACTGATAGGAAGAGAGAATGGGAGCAAGTATCTTACCCTTTTTAGATGCATTTGTGCTGAAGGC GTCTTGGTTCACTTGATAGAATATTACCCTAAGAAGTCACCTGAGAGTTCCTGAGCCAGAGCGGAACATT AACTTAACAGTGTAACATTTCTGCTCTATCTAACTGTACCTGATAATAAAATAGTCTATCCATGCCTGGA CCTGTGTCTGAATTGTCCTTGAATTTTTATGGATAAAAAATTGAATATAGGAAACAAGTTATAGTGAAGA GACATCTGCCTTCATTTACACATGCAGTACATTTTTACATCATAGACAAATGTGTACAAAATTATCTTAG GCAAATTGATATGCGGTCACCTATTTTATGTTACATACAGTCCTGAGGAGTCGTAGAGGGTAGTGTCTAG GCCACATATCACAGCACTTGTTTTTGAAAAATTCGAATATTCACCTGTAATTTCAGATAAATCCATTCTA AAGACATCTTAGGTATCTGCCACTAGTATTTTCAAAAGGTTTGTGTGTACTCTTGGCTCTCTCACAGCTC ATAATGCATCTTGGCTAGGGCAGAGATATGTGAAAAAAATGGCGTACGGGTCCTGCTAATGACAGCTGTC CATGGCTGTTAGGCTAGAGTTCATGTGTAATCCTAGGCATATAAGCCATCCGTCTGTAAACACCTAAAGA ATGATATTAGTTAAGATGAACAGTGAAAACAGATTGATCTATGTGCCTTCTGTTTCATCTCAAAATACTT AAACACAGAGCCCTTATCTTCTTCCTCAAACCTACATTTTATTCAGAAAGATTGCTTATAGAAGTGAAGT TATAATGATGAACATAAGTGAGAACACAACTTTTGGGTCAAATATGAAAGGGAAAAAAGTCTAGATCTGG AGGCAGGTTTCTTTTTAAATTTGGCTTTCGAAGATAAGGACGTGGATTGACACTGGTGTTCTGCTCTGCC AGGTGTTTCCATCTGCATTCCTCCCTTCCCCTCAGGAGGTTCACAGATCACATCTCACTTTACTGACCAG AGTGATTATGCCTTGTAGTACCCCCATAGGACAGGATTGAAATACAAATGAATAAGTCAATAAACACTTA AAAATATAAATAAGAGTAGAATAGTAGGTAGCCTTTGACATACCAACATAAAATTGCTACCAATTTAGTA CCATTATCATTTTTAGTGCAGTAATAAAGAAATTAAAAGTCTTAACATTGAGCATTGGACAAAAACACTC TGCTTGGCAGGGGGTGGGGGCTCACGCCTGTAACCCCAGCACTATGGGAGGCCAAGGTGGATGGATCACT TGAGTCCAGGAGTTCTAGACCAGCCTGGGCGACTTAGGGAGACCCTGTCTCTACAAAAAAATACAAAAAT TAGTTGGGCATGGTGGTGCGTGCCTGTATTCCCAGCTACTTGGGAGGTTGAGGTGGGATGATTGCTTGAG CCTGGGAGGCGAAGGTCGCAGTGAACCATGAGTCATGATTAGGCCACTGAACTCCAGCCTGAGCGACAGA GCAGGGCTCTATCTCAAAAAACAAAACAAAAAAACCAACCACCAACAACAAAACCACTCTGCTTTCCTAG AGTAGGGCCTTTATGTAGGATGGGTTGTGGCTGGGCAGTCTACAGGATCTCATCTAGCGTAGATCCTAAT TTTACCCTTGCCTTAGATATTTCTTTTCAGGTAAAATGTCCAACCGGGATTAGTCGCAAGAGGAAGTCTA TATGACTCACTGGACTAACTGCTTATTTTAAGATTCTGATTTTAAGATTAGAGGCTCTTGCACTTTATTT ATTTATGTATTTATTTTGAAACGGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAGTGGCACTATCTCG ACTCATTGCAACCTCCACCTCCTGGGTTCAAGTGATTCTCCTGCCTTAGCCTCCCGAGTAGCTGGGATTA CAGGCATGTGCCACCACGCCTGGCTAGTTTTGTATTTTCAGTAGAGATGGGGTTTCTCCATGTTGGTTAG GTTGGTCTCAAACTCCCGACGCCAGGTGATCCGCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGCG TGAGCCACCACACCTGGCCTGGGCTCCTGCACTTTAATTCAAGCCCTGTGACTTGCAGTGAGTGTGGCCA GGCAAGCACTCCCTGTCAGAATGGTATGATCCCTCTTTTCTGGAGGGCCAGCCTGCCTGCAGCACTGTTC ACAGGCTTGCAGGTGCCACTGAAGAGACCAGTGGAGTTTAATGTCTGGAATGTGTTCCACGTGGAAATAT AATTACTCTGTCATCTGGAACAAGCGATTTTAATTGTTAGAGAGTTCCTCAGTCCACTAGTTTGACTTTG GCCATGGTCGTACATTTAAGAACTTGGTTCAAGTTTTTTCCATGTTTAGGGTAATTAGGTGTCCATAGTA TATGAGGCTCAGCTTTCATACTCTATTCAACTCTGGAATGGCTGCCAAAGAAGCTGATTAAATCTTACCA GTTCTGAGCAGGGTGTTTTTGCCTCTTGTGTGCCAGGTGCCAGGATAGGCCCTAGGTGTCCCAGATGGTT CCTGTCCTCATGGAGTTTACCATCTAGTGATCAGATTGTACCTAAATATAGTTTGAAGGACCCATATTTT AAAAGCAAACAAAAATGTATTTATATATACTCATTTAGCATGGATATTTAATACAAGTTAATTTGGACAG AAAGTAGGGTAAAAGGGGGAAGAAAATAGAAAAATGATAGCTGTTCACAAACATTTTATGTCTCTTTTGT AGTAAACTTAAGTCATGCTGCCTGAAGGCAGAATTAGGCTTTGCACATTTATTTAAGAAATACTGGCCAG GTGCAGTGGCTCACGTCTGTAATACTAGCACCTTGGGAGGCCTTGGTGGGAGGATTGCGTGAGGCTAGGA GTTTGGGAACAGCCTGGGCAACATAGTGAGACCCCATCTTTAAAACTAAAAGAAACCGATTAGTCGGGCC TGGTGGAGTGCATCTGTATTCCTAGCTACTCGGGAGGCTGAGGTGGGAGGATCACTTGAGCCTAGGAGTT TGAGGTTGCAGTGAGCTATGATGGCTCCACTGTACTCTAGCCTAAGAGTGAGACCCTGTCTCTAAAAAAG AAAGAGAGAAAGAAAGAAAAAGAAAAGATTTTAACTTCTAGTCATTCAATCAAGAAGTGCCAGACAGCAT GGTAGCTGCTTGAAATACAGTACTGAGTAAGCTGCGGTCTCTCCCTGGATATAACTCCTAGTGAAGGAGG CATGTTCAGTAATCAATCAAGCTTATTTAATTGGGTTGTGGTAAGTGACACAAGAAATATAGGCTGCAAG AGTATAACAGGGGACCTGACCTAGTCTGGAAGGTGGAAGTGGGAGGCAAGTAGAGGCCTAGGAGGTCTTC TCTGAGGAAGTGAGCATTTAAGCTGAGATTTTAAGGATGAAGAGTGAGTTTAGGAGGAGCCAAAGGTAGA CTCTCTTAGGCTCAGGAATGGGGAGCATGTGGCTTAGCCAAGGAACTGAAAGGCCAGTGAGTCAAGGTGG TGGGGAGGGTTGGGGAGGGGTGAGGACTGTGGGGACTGTGGCAGGCGGTGAGGCCCTGCAGGCCCACTCA GTGCTTTGTGCCTCTCACTGTCCTGGACCTGCCTCACATGGCTCCTCCAGTAACTTCGGTGTGCCCCGTG CTGTGCCGAGGGCAATGGAATGCATCATCTCATGTAATCCCCACAAGCCTTGTGAGCTTGATGCCATCAT TATTCTAACTTTACAGACGAGGTAACTTACGGTTAGACATTGGAGACTTAAGATAAATAGCTAAATGTTA CACAGCTAATAAGTTGCAGAGCTTGGATTTTAACCCGGAACTCTCTAATTCTAGGGCCTATCCTGCCCAT TCATTTATACCTCTAACAGACATTAACAAAAGACAGAGATTACAAGTTCAGCACAATATAAAGAATTTTC CAGCAACCAGCTGTTCAGAAATGTAGACGGGGAGAGGCACGTGCTTCCAATGATTATGAGTGTTCATTCC AGTGGAAACGTGGTGGCCACCTGTCAGGGATAGAGGAGGAAGAAGCTTGTGCCAGATGAACCCCTAACCC GCTTTTGATTACATCTGGGATTTTGCTTCATTGTACATATGTTTTCTTCCTTCAGTGACCATGAAAGACA CCAGGTTGACAGCACTGGAAACTGAAGTACCAGTTGTCGCTAGAACAGGTAAGCTATAACCAGGCCAGTG GTTAGAGGAAGATGGGAGGGAATTATCTTGCCCATGGTCGTGCATTCAGGGATTTAACATTTACAGTTTT AGCTACTTGCCAGGAACTGGACCATCTATGGCATGAAGGGATTAGTCACATTACTGATGATTATTAGTTG CTTGTATTCAGTGCCTGACACTGTGCAAAGCGCATTATATGCGTTACTTTCTTCTTCACAGCCACGCTTT TGGTGTTTCCCCATTTTACAGGTGAGGATTCGGGTTCAAACATGTCAATTTTCCTAAAGATGCATAGCTG GTACTTAGTGGACTCAATTCAGCTCTGTTTAGCAGCAAAGTTTGGTTGTGACCACTTCATTCAATTAAAG CCTGTGTGCTGGCACAAGTCATTTAACTAGTGCAGACGTTCTTAACCCTGGCTGCACCTGAGAAATCTGC ATGGGTTTATAAAAACAAACCAAATGTGATGTCCGGATTCCATCCCTTAGTTAACCTGCTCCAGAGTTTC TGTAAGCTCTCCAGGTGATTCTGATGTACATCCTGGGCTGAGAACCCTTGAGCTGGTGAGTGAGCATTTG CATCTTAACATGGCTATATCTGTTGCTTTAAATTAATTTTGGGGGATAAATTATATGCTATAGTAGTTTT TAGGAATTGGATGATCCTGTCTCAGAATATATCCTTCATAAATGTTGAGGCGCCGGCATTTCCACGGATG GAATTTCCTCTTAGTGACTTAACTGATCACTGAACTGTAATTTTGGTTTAGCAGTAATAGTGCCAAGCGC AACAGAGCTGTGTATAGGAAGGGTGTAGGGAAGACGGGAGGTGCTTGGTCTGCTGTCTTTGTACATGGAC AGCTCTGTGACTCATGCCGAGGCTCAGTGGTTGCTGTTTAGTGTATTCTGTCACTGTCTGCCTCACCTCT GTCGTAGGAATTGTAAAATAAGGTAGGGATTTTTGTCTTACAGCTCTACATTGGTTCATAAGTAGGGTCT TGATACAAATTGTAGACTGTCGAAAGTTAAGTATTGTTCTCAAGTAGGGAAAGTTTTCTGAGTTTGATTT TTCATTTTCAGTGTTTTTGTGTATACTTCATACTGTTCCTTTTTTAGAAGTCCACTGTATATGAATTTGA ACCCAAAGTCAAATGGTTAAGTGTTCAGATCATTGAGGTCCCCAAGCTAAATATCACCATCATAAAATGT AAATTCTGGGATACAAAAGTAAATCTCAAATTTTATTAAACATTTTTCACGATAGTAATTGTATTGCATT TTAGTAGTCAGATTTTAGAAGTTTGGAATTTTAATATAGGAAAAATACTTTGTGGGCACTACCGGCTGCT AGGTTACTCCTGTGGTCACTATGTCACATGTGTAGTATCATCTCAACTGGCACACAGCGTCATTGGTAAC ATTTTTGGACAAAGCAGAATTCAGGAAAGTTTCTGGTAGATGGTTTTCTGGAAGGAACCTTGTACCTGGG ATTCATAGCTTGGCAAGCCTCAAAGATCCTTACTCTTCAATTACTAAAAATTGTTGGCCGCCTTTAGCAA TTATTCTTATTTTGAAACAAAAAAAACCCCAGCTTTTAATAGCATTTTTCTTTTTTCATGGGGTACTCTT GTTTATACTTTTGTCCTCATTTTTAAGACATTTTTGGCCAGGTGTGGTGGCTCACACCCGTAATCCCAGC ACTTTGGGAGGCCAAGGTGGGAGGATCACATGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTAA AACCCCATCTCTACGAAAAATACAAAAATTAGCCAGGCATGGTGGTGTGCGCCTATAATCTCAGCTACTC GGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGATGGAGGTTGCAGTGGGCCAAGATTGTGCCATT GCACTGCAGCCTGAGTGATGGAGCGAGACTCTGTCTCAATTAAAAACAAACAAAACACCAAAGCCAAAGC CAGACAGCCACCAGATTTTGGCTGAGTATAGAGACTGAAACTGAACTTTGGCAGATCCCTGCTTTCCATG TTTTTTGAGATCATAAGTATCATTGGATCAAATCTGGCTACTAGTTGTATAGTTTAAACTTAGTTCAAGG TTTCTCATGAATTACAAAGTATCTTTTATTGAAAAGTGATGACTGAGAACCTCCCTGCTGCTTTAGATTG GGTGGTCAGGGGAGGCCCATCAGATATCTGCGAGACCGTCAGCTGTGCAAGGATGTGGGAGAAGAGTGTT TCATGCATAGAGGGAACAGCAAGTGCAAAGGCCTTGAGCAAGAAAGAACCAGTATTCCTGTGTTTGGGAA GACTGGGACTAGAGCAGAGGAATGAAGAGGCAGAGGGGGGTTGGGAGGTTAATAACTGGCTGGATCTTAT GAGGCCTTGTAGGCTACTCATGAGTTTCATAAGTTCCATAATGTTATTGGCTCTTATTAATTCCATGGGA AGCCATTGGATGATTTTAAACAGAGGAGTGAGATTCTGATGTTTATATCTCAATGTCTCTTGTGGTTATT TGGAGGCAAATGAATTTTGTAGGGTAGCATGAATACAAGCAAGGAGAGTAGTGAGGGGGGCTGCTGCTCC CTTGTCTCTGAGAGATGATGCGGGCTTCGACTGAGGTGATAGCAAAGGGTTTGCTGATGGATTAGATGTG GTGGTGGGGGTGGTGAAAGAGTCAAGGAGTCACCTGGGTGTTTGCTTTAGACTGATGGTAGTGCCTTTTA CTGAGATCCAGAAGATGGCAGAGTGATGGATTTTGGAGTGGAGATTGGCCTTGAAGGTCATGCCCTCTGA ATATGACTAGCATCATCTACAGCACTGTACTGTGCACTGTATGTGGCCACTAAAGATAATATTAAACTAA ATGGAATATTGCTTTAGCATGTACGATACAGAAATCCATTCACCCAGTTGCTGTCTTTTAACTTCTCCTG TATGGCTATTTTCTATGGTGAGTTACTTCCAAAATGGAAAAGAGACTTATGGCTAGAGACTTTTGTGGCT AACACACTGATGCTTCCTTGTGTCTGTGGTGCTAATCTTTAATTGACTTTTCTCAGCCAGTCTTCTATAG GCTGTAAAGTGTGTTTAACATGTGTATATTTCATCCACCACTACCACCACCCCTGACTGAGTCCATGTAG GGCTGGTTTCTTCCCCTTTTTTGTACACATATTGAACCATGTCTTTTTTTCTGCTATAAAACATTTAATT CTTCATTGCACTGGCTAAATCTGTTTTACCTGCTTAACACCTTGCACTTACTGTAGACCCTCAAATGTTT GAATGTGCTTAAAAAGGAGATATTCTAGTTGTGGGACTGATTCCAAAAGCTATGATTTAACTCTTAGGAG GGCTTTTTAGAATGTCAAAAATGCTTGAACTTGAGCCACTTATGCGAAGAATCTCACATAAAACCCAATG TTTATATTTTTCCTGGAGATTAAAAACTATGGTAAACAGTAGAATTTTGGAAGGCAGCTATGCTCACCAC TATACCACCAACGCGGCCGACAGTAGGATTTTGGAACCAGAGAGAAAAACTTGTTGCCAAAACGTGTTTC TAATGTGTTTTAGAATAAAACCTTACTTTGCAAATGGAAAAACAAGCTAGGTGGCCCAAGCTGATTAGCC CACACTATCGCCAAGTTGACTGGATGGGCGCCATCTTTGTTTAAAATTGAGCTCATGTCACTCCGGGCTC TGGGGCTGCCTGCATTTGGAGGACCAGATATGACATTATCGTCTTCTGACTACACAGAAGGCAAACTCAG AGTCTCCCTAGACAAATAGTAGGTAAGTAACAATTTTATTGAAACAAAACCAAACTTAGGGACAAGATAC TTTTAAATTTATGAACAACATTCTTTGTCACTAATTGAGAATCATTTGTGATTTACCTGAAGCAGAAATC AATGTGGGGGTTAGCTAGACAAGTGTGCCATTAAAAAGTCATCTTGAAAGTGGTGGCCCAAAGATTTTTA CTGGTATTTTTTATGATAATATACAGGTACTATGCAGCGAGTGTTTATATGTACCTGATACCATACTAAT CGCTTTTTGGTTTTGAACTTTTACGGTAGAATCTTACCAACGGTGGTCTCACATTTTGGAGCCCTTTGAA ATTAACTTCCTATGTGATTTACTTGTAAGATTTTTATTTATAGATATGAGTCAGCAACTTCCTATATCAT GGTATCAAAAAGGCATTTAGACATTTTAATTGATTTTTCTGATAAATGAACTTCTAACTTACTAAGAGCC AAAATCAGTGAATGTCACAAGATTGTAATTAAATAAGAATATAGATGATAGCAAGTTAATACCTGGCAGT TTTTGGGGTCATGGCTAATTTAAATTTGGCATTCTTGCAGAAGGAGCTTATCTCTCTCTTTTTTTTTTTT TTTTTTTTTTTTTGAGGCAGAGTCTTGCTTTGTTGCCCAGGCTAGAGTGCAGTGGCATGACCTTGACTCA CTGCAACCTCCGTCTCCCAGGCTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGGTGGGACTACAGGC ACACGCCACCACACCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGCTTCACCATGTTGGCCAGGTTGG TCTCGAACTCTTGACCTTAGGTGATCTGCCTGCCTCGGCCTCCCATTATGCTGGGATTACAAGCGTGAGC CACCATGCCTGGCCTCAGCCACTACATCCGGCCTCAGCTTAACTCTTTAGTTGGATTTTTCTTTATCATA GTGTTTCTCAAAAATAATTTGTGTCTCACTTTAAGAATTACCTGGAGTGCTTATTAAAATATAGATTCCT GAGCCCAAAATACAGTTTTGGAAGGGGCCCAGGTATTGCATTTCTAGCAAGTATCCCAGGTGGTTTCGAT GCACATTGAAGCTTAAGAACTGCTACTTACACTTACTGAAAGAAAAGGAAGTGTTATCCTTTTTGGGCAT GCATATCCCCATGTGTAAAATAAGGATGATACCTGCTCACACCACATCACATCACATCACAGACTTGCTG TGATGATCAAAACCACAGGTTAGCTTAGTGTGACACTTAAGGGCTTGGGGCTTTGGAGTCGGGCATACCT AGCTTCCAATATCAGTTTTTCTCCTCTGGTTTTGCCTCTTGCTAGCTTTGTGACCCAGAACAAATGGCTT GATCTCCATTCTGCTCCCTGTACAATGGGGACAAAAGTGCCAATTACATGGTGGTCATATTAGGAGTATA TACAATGATGTTTGTGAAAGGTGTACAGTGCTTATGAATGATAACTGTTGTTACTTGTTTTAACAAATAT AGCCTCAGAGATCAAAGTGGGGGAGAAATCGTAAATGTGTATAGTTACACTTGGGAATGAGCTGCTTTTT GTATATCAAGATAAAGCAGCTGCTCTACTACCATAGAGAGCTTGGGTTTTGAAGGGTGAGTTTTTGAAGA TTTGCCCTGATGATCCCATCTATGGATACCTCCCTGTAGCCAGTGGTATTTGGGTGTGCAATTAGATGTC TCAGATGAGAGGTATATGCTAAAACAGAGAAATGATCCCCAGTTTATGCTAGATGTTGGACTTAACAGAC TTGTGACCTAACCAGCTATACTAACTCTTAGCCATTGATGAGACTGTCAAGAAGGAAATAGTATGTATTT AGTTCTTTTGCTGAAAAAAGACTGTCTGCTTTTTAGATCAATAATTTGAAATATAAATGTGGTCTTAGCC AAAACCCAAGGTAGAATCAGAAGTAGGAATAAAACTTAGATTTGATCCTATCATTAAGTTGCTGTGACTG GTATCAGTTTTTAAGGTTTCTTTCTGATTGTTATATTTTGTAGAAACCCTCTTCATAAACTCGCCAAAGA ATTATTCATACACTTTATCTTCTTTTATCAGCTAAATGTACTCACTGTTTGAATCAGAGAATTCTGGCCA AACTTTCCATTGCATTGAACACGTGCATTAGTTTGTCTTGCAGGTATTTTCTTTTTTTATGGAGAAAAAT GGGGCCATTTAGTGACTGTTCATCTTCCTTTTTCTCAGTTTGGTAGTGGCCCCAATGAAGAACCTTCAGA ACCTGTAGCACACGTCCTGGAGCCAGCACAGCGCCTTCGAGCGAGAGAATGGCCCAACAAGCAAATGTCG GGGAGCTTCTTGCCATGCTGGACTCCCCCATGCTGGGTGTGCGGGACGACGTGACAGCTGTCTTTAAAGA GAACCTCAATTCTGGTTAGCAAAATAATATCCTTTTTAGCTTATCTTCTAGAAAGAAGAGATTGACTTTA GAGCCACTAGAATCCTGCTGATACATTTTAGTTTTCATCTTCTGAAAAGTTTTTTAAACACCCAAAGAGA GTATCTATATGTGTTTTAAACTTTCAATTATGGAAATACTCAAGTATGCACACACATGAAGTAAGAATCA TGCAGTGAACCCCATGAATCCAGTTTCAAATTCTTTCCTCCCTGACTCTCCCACCCTCCAAATATTTTAA AGCAAATTCCAGATGTTGCTTTAACTGTAAATCATATATGTGGTTTTTAATATGAAAAGTGCTTAACCTC TTTTTAATATGAGAAATACAAATTTAAATAGTACCCTTTTTTGCTTACCAGGTTGGCAAAATTAAATATT GAATATAGAAATGGGCACTGTTAGCAGGAATATGAATTGATGTTCAGCCTTTTGGAGCATCAGTCATCAA TTTTAAAACACATACCATTTGGGCCATTTATAAGAATCTGTATCTTATTACAGCTTTGAGTGAAATACAG TGAAGAATTGGAAAAACCCAAGTATCCTTCAGTAGGTGAATGGTTAAATTAGTTATGTAGAGCCATGCAG TGGAACACTAGGAGGACGGAAAGAAATGAAATAGGCCATAGATGCTGACGTGGGAAGGTGGTTACAACAT ACTGTTCAGTGGAAAAAACACACACATGCACAAACTGTGTCTGTGTCTGTGGACATGAGGGCTGTGTGCG TGTGGTTATACAAGTAGAAAAGGGTTTGAAGAGACACACTCTAAACTTAAGGGTGTTTATCTGTGAAGAG TGGGTTGGGAGGCAGGTGGTGAGGAGCACTTTCATTTTTATTTTATGTACTTTTACATAGCCTGAATGTT TAACAGTAGATATGGATTATTTTTTGTAATTAAAAAAGCAATAAAGGGCCAGGTGTGGCGGCTCACGCCT GTAATCCCAGCACTTGGGGAGGCCGAGGCGGGCGGATCACAAGGTCAGGAGATTGAGACCATGTTGGCCA ATGTGGTGAAACCCCATCTCTAGTAAAAATACAAAAATTAGCCAGGCGTGGTGGCAGGTGCCTGTAATCC CAGCTAGCTACTTGGGAGGCTGAGGCACGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTG AGATTGTGCCACTGCACTCCAGCCTGGCAACAGAGTGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAG GCAATAAAAATGACTTCATATGTTTTTATGCATATTTAGGCAAATAAGCTTGGAATATCTTATTATTAAA TTAAGAAGGCAGAACTGTAATGCTGCACAAAACTTAGAATAGCATATAAAGAAACATTTTCTGGATTTTG TGACAGGAAGCTGTGTAAGGTAAATTTAGGATGTTAAGGGGAATAAGTATCATCCATTGCCCTTTTCTTG ATTTAGACCGTGGCCCTATGCTTGTAAACACCTTGGTGGATTATTACCTGGAAACCAGCTCTCAGCCGGC ATTGCACATCCTGACCACCTTGCAAGAGCCACATGACAAGGTAATGGCTGAAATATCATAGGCATTTCAT ATGTTCTTCATGAGTACAACAGCTTCTGTGCACGGCCACTGTGCAACTTGTCCTGAGCTTATTCTTTTGA TTTCTGTGCGCCACTGATGACATTGTTCCCAGTTTATAACTACATATAAAAATTACTTTGTAGGACCCAT GATTCTTGAAAAGTTTACAAAATAAAACATATTTCAGAGACTGTTAAAGATCTTGTTTGGGCCGGGTGTG GTGGCTCACGCCTGTAATCCCCTTAGGAGGCCGAGGCGGGTGGATTGCCTGAGGTCACGAGTTTGAGACC AGCCTGGCCAACACAGTGAAACCCCGTCTCTACTAAAAAATACAAAAAATTAGCTGGGCGTGGTGGTGGA CACCTATAATCTCAGCTACTCAGGAAGCTGAGGCAGGAGAATCGCTTGAACCTGGGAGGCGGAGGTTGCA GTGACCTGAGATTGCACCATTGCACTCCAGGGCAACAAGAGTGAAACTGTCTCAAAAAAAAAAAAGATCT TGTTTAAAGAAATCTTACATTTCCAGTACTATAATTGTATAGTGATGATTTGGCCCATAGGTACCCATCT TTCAACCCATACTTTGAATAGAATTTTTAGACTTTTATCGATATGGAAAAGCTTCAAGTACAAAGGACTA ACATGACAAATTAATGAGTCTTGTTTCCTAGCACCCGGCACTTGGAGGGCTCCTTCATGTTTTCCTTTTG TTTTTAGTAAGTAGCTAATAAAGCATTGTTATTGCAGACTTTGGTAAGTCTTAAGTGTATATATGAGAGC AACTTCCCCAGGATTTGAAGACCTTGTATTGCATGCCTTTTACAGTACATCTTGTTTTGTTTTGTTTTCT AAAGAGGTGAGGTCTCATTGTGTTCCCTAGACTGGAGCGTGGTGGCACAATCATAGCTCACTGTAACCTT GAACTCCTGGCCTCAAGCTATCCTCCTGCCTCAGCCTCCCAAAGTGCAGGGATTGCCGGCATGAGCCACT GCGCCTGGCCCGTCTTGTTTTTTTGTTTACTCTGGTCTGAAATGTAACTTCTACTACCTAATTGATACTT GAGGCCAAACCATGTAGGCTGGGTTGCTCTAGCAATAAGTGGCTGCTTCCAGCAGGATCCCCTCATGGCT TCAGTAACCTATCACAGTTTGGGACTGTTGGTTATTGAGGGGCTGTGAACAAGTCTCCCCCTTTCTGCAT GCGTGTATTGTAGGGTCCTTTTTCATGAGCTGCAAACTGGCTGCCTTTTGTCAGGCCAAATGCAGCAGTG TTTTGTTTGCTAACGTGGTTTTTAAAATCTTGAATTTGACCTTTTATCTGCATGACCCTTGCTTTACATT AGAGACAAGACTTGAGAGATTGGAGCACATCATTGCTGTCTTTATTTGTGTTAACTTCATACATTCATGT GAGGACTGCCCTTGTTCTTTTACATTTTCAGCACCTCTTGGACAGGATTAACGAATATGTGGGCAAAGCC GCCACTCGTTTATCCATCCTCTCGTTACTGGGTCATGTCATAAGACTGCAGCCATCTTGGAAGCATAAGC TCTCTCAAGCACCTCTTTTGCCTTCTTTACTAAAATGTCTCAAGGTAGGATGTTTGTAAGGATTTGAATG AAATGGTTTTATGAGTATAGTTTCTGAAATTTTAGGCAACTTAAAGCAAGGAAGCTAGATTTTAACTTTT AGAGTTTAAAACCTTCTAGGCATTTGGCTTTTCTCAAATAGAATGTTGTCCAGAGTTGGTACTTAGTAAG TTCTCAAATACATCACTATGACTATTGAATACCTTGTCCATGCAAGTATGGAAAAATTTCGATCAGATGG GTTCAATGTTACATTATTCCAAACCTCTTGATTTCGTCATCGTTTAGCCTTCCCTCATTTAAAAACATCC TGGATTATCTTTTGGGAATCCCTGTTTCTAAATTATCTTTTAGCTAATAGAAAAATGGCTTAAAGTTTCT GTTAACCATTTAGGAGTATGGTCTGGTTGCAGCTATAATTAAGACTTTGTTGATGTAAATTCTACTAAGT TGCATTCTATTTTTTGCACTAAATTTAGTGCATTTTTCTATATAGGGAGTCAAAATCTAAATAGAACTTT ATGGTTTTAGTTTTAACAGTGGCGTGCAGCCATACTCAGGGTTATTTGTTTAATCTGTTTTAGTTCCTGG ACTTGTTTTCTATCTATAAAATAAGAAAATGTGGTTAATATTAACTGCCTGTACCTCACAGAGACATGAA AATATCCAATAGTATTTGTTCCAGGATGGCAGTACCATTGGATTCATCTGCTACAGCACCATGCAAATTG ATTTTTGTGTCTGCCAAGAAGGGTAACTCTTTTATTATCCCTAGAGGTGGGTCCCAAGGAGTCACATTGG CAGGGTATTATAAAAACATGCATTTAATTCAGAAAAAATAGGAACAGTTTTAACAACTTAATGTTTTTTA AACAAATGGATTGATGAGAATATAATCTAATTAATGGATTGGTGAGAATATAATCTAAATGGATTGATGA GAATATAATCTAAATGGATTGGTGAGAATATAATCTAAATGGATTGATGAGAATATAATCTAATTTTGAG GCACATCATTTAGTTCAGATTGCAAAACACTTATCTTTTCCAAAAGAGTACGTTTTGTTAATCATGGATA AGTCTTCAGTTAGACTGTTAGGAAAATGAAATCAGGGCTAGTTCTTTCTGCTGAGAATCATTATATAGTC TCATATATTCTCAATTCTCCTACCAATATATTATTCTTACTGGATATCTTCCGTAATGAAAGGCTTGATG CTTGATGTAAAAATCAAAATATATTTAAAACTTTATTCCCAGACTCATAGATTCCTATTCTAATAGGAAT AATGGATGTCTTAACCTACATAGTAGTCTTTTGATTAATATCTTGTTTCATAAATCTGAATTTCATCTAC CTGGCAAACATTCATGATTTAATTATGGGTCAGGTGAGCTGCTGTAGCTAGCTAGTCAGAGCTGATTGAG TATCCATTGGGTGTTAAGTGTCTTCAGTTAGCCTGAAGTTATTTATTTGACTTAATATTTAAACTGTAGG CGTGCTGAAAGGTTTCCATATATATATATTTTAATTTACTGGTCTCTAAATACTGCTTTGAAGTGAGCCT TTAAGTTGACTTGTTAGTGCTATATGAATTTCTCCTTCAATTATACTTCTGTTGTAGTTCTTTAAAAAAT AGTAAGTTACTTGTCAATGTGCAGTTTTTTTTTTTTTTAATTAACAAAAAGTAAGTATCTTAGGATTTGG TTGAATGAATGAAACAGAGCAGTGCTCCTGTGTTTTGTTGAAAAGCAGCTCCTTTTGTTTTCATCCAACT GCTATCAATAGGGCATCCTAAGGCTGCAGGACTTGGGTGTCCCCAAGTCAAGTTTGAACTCGTCTCCCGG ATGCCTTTGCATAGGTGTGTTGTAAATGGTCCTCACTGACTCATTACAGTAGAGTTGGGGCTCAGTGTTC TGTTGAGTCTGTTTGAATGTTATCCCTTCAGTAATCCTTAGGGATAGGGAAATGAGTACGTGAGTCAACT TGTGATTTGTGATTCTCTCAGTGTTTAGAGCCTCTTCATGTACTGTACAATGCCGATCCTGGTGCCAGTG CCTGACAGACGTTTCCTGTTTGACCTTTTCTCCTGCAGATGGACACTGACGTCGTTGTCCTCACAACAGG CGTCTTGGTGTTGATAACCATGCTACCAATGATTCCACAGTCTGGGAAACAGCATCTTCTTGATTTCTTT GACATTTTTGGCCGTCTGTCATCATGGTGCCTGAAGAAACCAGGTACAGATCTCCTCATATACCTGTTGG GCCCTGTGAGGTGAATGCTTTCATTATTGATTAATTGCTCATATGCTGTAAGGAATGGACATGTAGACTT TTATAGCTGAAATGAGTGGTTTTCACCAGACAGATGAGGGAATATCTTGGGTGCATCCACTACAGGCACA TAGAAGAAACATGACTGTTGAGATAACTTTTTTTATTTTCTTGGCTTAAAAGGATTAGTCGTCAGAGAAA TTGAGTGGTAGGATGTAAAACTTTATGATTGTTGATAAACTGAAAAACAGCCTCCGTCTGTATTGCAGCA GTACAGGACTAAGCTTGTGGGACATTTCTGTCTTCCTTGGCTGCTCTGTTGTGACAGAACGCAAATGTCA GATTCTGAGAACCCACTCGTTGTACCTGTAGGAGTCAGAGGGAAATGCGGTGTGTCCTGATTAGCACTCC AGCTTCAAATGCAGTGGTTTTTTTTTTTCCCCTATCGGCAGGTAGCAGAGCTCTATCAAAGGGATCAGAA GCTGTAAGCATGTGAAATTTGGAATCTTTGGGTTATCCCAGTGTGAGGTATTTCTATCAAAAGGGTGAAG TATGTCAGACCTGTGAGACAGAACACCGTGCCTTCCTGTATAGGATTAAATTACAAGCATAGGCCCACGT GGTGCCTGCTTGTTTAGTAGGACCTTTGTGAAAAAGGAATGGTCTGTCCATTATTTTGGAGGACCTTTAT GTATACTGTGGCCGTGGGTTTCCACAGGGTCTAGGTAAGGCTAAATTAAGATGTTCAATTTCTTTCACTC TTAGTTCTTTAAGCTAATTTCTAGATAATAGTTTTTTTCACTCTGTAGTTATAAATCTGCATAGCTAAGA CTACATACTGATTTAAAAGAGTCTCACACATTCATTCTGTAAATATTGAGTGCTTGTTAAATATCAGGTC CAGTGCAAAGCACCGAGAAATAAGTAAGACAGTTTTTTTCTCAAGAAGCTCGTACTGAATTCGGCAATGG AAAAGTATAAATTTTACAGAGAGCTATCATCATAAAGATAGTTCAGTATTGTGAGAATGTTTGGGATCCT TTTTGGGCAGTGGCTGAAGAGGAGGGCAGAAGTTAGATCAGGAAGAGCCTTCATGGATCATACTAGTAGA CTGGAATTTATCCAAAACTTATAGGGAGCCATTGATGGATTTGAAATAAGGGTGTCTGGTGTGTTCGGAT TTGTTTGCATTTTAGAAAACCACTCTTCCTGTCTTTGGAGTGAGGTGGGAATATACATAGATAAAAAGTC CTGCTGGCAGCCACTTGTTTATAGCTGTTTTGCACTCCTCAATCTGTCTCCAACTAAGAGGCTCTTCTCA ACGGGTTCCTTTTCTAGGCCACGTGGCGGAAGTCTATCTCGTCCATCTCCATGCCAGTGTGTACGCACTC TTTCATCGCCTTTATGGAATGTACCCTTGCAACTTCGTCTCCTTTTTGCGTTCTCATTACAGTATGAAAG AAAACCTGGAGACTTTTGAAGAAGTGGTCAAGGTAAATTGAAACTGCTTGTTTGTTTGCTACTTAGTATA CTGTTTAGATAGGCTGCATTTATACCTTTTGTATTTAACGGCAGACAGGGAAATTTTGAAAAGAAATTCA GTTTTCTTCCTCGCCACTCCAATCCCTAGGCAGCCACTAATCTGTTTTCTGTCTTAATAGATTTGCCTAT TCTGGACATTTTGTATAAATGGGATCATATAATATGTGGTCTTTTGTGACTGGCTTCTTTCACTCAGTAT AATGTTCTCAAGGTTCCATCTGTGTTATAACATGTATCAGTACTTCATTCCTTTTAATTGTCAACTAATA TTCCATCATTTGGATGTTCCACAAACATTCAGCCCTTTATAATTTGTCAACCCAACTCTTCTAGCCAATG ATGGAGCATGTGCGAATTCATCCGGAATTAGTGACTGGATCCAAGGACCATGAACTGGACCCTCGAAGGT ATAGAAACTAGTGTCAAAATTTTAAAGAATCTTTCGAGAGATTGAAAATGTGATCTAGGAGGTAATCCCT GTTGAGGTATATTTGGGAATATAGATGTTCTACTTACAGAATCAGTCCACTTGGAAGCACTCATACAGCT AAAATTTGTGTGAGTTTAAAACATACTCTTCACAGGCGGAGGACTAATAACATTTAGCAGAGTGGAGAAA GTTGCAGCACAAGTGCCTGTCCCCCAGAAAGGCTTACACCTCAGTAGTGCCAGTGATGGGGCGATGCAGG AGGTGAAGCATATGGCTAAAAACAAGGGGACTGCAGAAAAACAATTTAGCATATATATAAATCTGGCTTT GCAAAATGGAGAAAGGACTTCAGGGAGTCCTATATTAAGTATTTGGAGTCCCTGAGGTCCTTTCTCCATT CTGCAAAGCCAGTTGACTATACCATCCTCCCCAGGGCCCTACAGAGGCCCCCAGGTATGTTCTCTGGAAA AACCGAACCTTTGAGTCCCTTGATTGAAGGATTCCAGGCACAGTGGAGAGTGGAACTGAGGGTAAGACTG AGCGAGGGAGATAAAGGAAATTTACAGACTGAGCTGTGGGAGGCCCAGCTCCTTCCCTCTGCTTGTCTCT GCCTGGTAGCCAGGCTTATTATGCTCCCCAGTTAGGGGAGCTGGCCCTTTTTGGGGAAACTGACCCATGG ATACTGACACTTAGGGATCTCCTGCTGAAAAAGCTAGCTCACTGCCTGATCCCCCAACAGCGAATCTCAC CTCACCACAGACACTGCCTCTACCACACAGAGCCTCAGCCAGCTTAAAGCAGTTTATTGTGAGATTATAT GTAGAGAAGTATAGAAAATGTGTATGTAAAGTTTAATAATAACACAAAAACACATGTAGCTGGCACCTAG CTTAAAAAAAACAGAACATTACTGGTACCTTAGAGGCTCCCCGTGGAGAACCCCTCTTTTCTCCCTACTA CCTCAGAGACAACTACCATTGTTGCTTTTAATCATTCTCTTGCTTTTCTTTGTAGTTTTACTGTAGGTAT TGCTTTGTTTTGAAAAGCTAGTTGACTAGGAGGCAAAGCCTGGTTAAGAGAAGGGCAGTCTTGTCACTAG TAGTTGAAGGTTTCCAGGAGATGAGAGGAGGACCAGCGCATCTGAGTCTTGGTGTGGTTTCACTGTCCCT GAGGTTTCACAGCCCCTTCTGGGAAGTCAGTGCACAAGGTCATGAATGAGTCTGGGAAACACAAGGCTTA CCCTCATCAGAGCGTCTGGCAAGGCTTCTAGCAAGGGCAAGGCACTGGACATGCGTGAAATATGGCAGGC AGGGAAGCTGCTCTCTGCGCCTGCTTTCAGCTCTCAGGAATAGGTCAGACAGAATCCTTCTGTGGGATAA AATGAATGTCCTCTGCTGATCAGACAGAGGAGGGAGAGTAGGAATTTCATCAGTATGTAGTTAAGACAAG CTAAGTACAGACAAGTTATACAGGCCAGGGTCACCTGGCTCTGTCCCTCATTAAAAAGATAGTGCAGGAC AGCAGGAACTTTGAGACATGCCTGTCTCTTGGCAGCTGCTGTTCTGATCCGAACTGGTTCTCGTCTGTGC CTAGTACCCAGCTGTCATCCTAGTCTCCTGGGGCTTTCCTTCGCCTCTCTCCTGTGCAGGATCTCCCATT TCCTGTATCTTGTCTTCTTTCTTGGTTTACTCTTGTTTAATAGGACATAGCCTCTAGGAGCTTTTTGAGG AAGGATGCAGTGTTTTGGCTGGTGTAGACTTACAGGTTGAGAGTCGGTAATTTGAAGGCATTCAGTAATT TGAAGGCATTATTCCATTGCCACCCTGCTTCCAATGTTGCTCTTAGAATTTCTGATCATCTGTATTTGCT GTGTTTTTCTCTAGGGGAGCTGGTAGGGAGTTCTCTTTGTTGTCATAATATTCTGAAATTTCCAGTGATG TATGTTGGTATGAATCTATTCTCATTGTTCAAGCTGGAAGCTCTTCAAGTTCTATGATATTTTCTTTAGT TGTTTTGTGCTTGATTTCCTGTTTTCTCTGTCTTTCCTTCTAGAAATCCAGTTCATCCCTGCACCACATA ATGACATTTCAGTCAATGATGGGCTCCATAGATGATAGTGGTTCTGCGAGATTATACCACCACATCTTTA CCGTACCTTTCCTAGGTTCAGATATGTCTAGATACACAAATACCTACTGTTGTTACAGTTACTGCAGTCT TTAGTACAGTACCATGCTGTGCAGGTTTGTAGCCTAGGAGCCTATAACATCTAGTTTTGTATGAGTACAC TCTGATGTTCACACAACAAAGAAATTGCCTAATGATGCATTTCTCAGAACATGTCACTGTCATTAAGTGA CACATGACTGTATACTTATACAAGGAGTTTTCTTTTCCCTGCATAATCTGTTTCTTCTAAGCTTCCTTCT TTTCGGTTTTGTGTTATTCTTTTTAAATCTTTGAGGCCTTCTGCCAGGATCTAGTAAACTGTTTATATAT GGGGAGACAAAACAGCTTTGTTCACAGTGGTGGGACTTGTTGACTTTGAGCTTTGTTGTATGTTGAACTG AGCATCTGTTGGAAATAGTGGTGTCGGTATTGTTTTCTTCTTGAGCTGGTCATGTTTTTTAGAAAGTAGT CTTCTGATTTTCAGGCTGGTAGGGGTCTGACTACCTCTGGGGGGAAAGAGGCTGGTGGTGAGGAAGGGTT GGTGGTCTGGGCATTCAGAATGTATATGCTTCACTTAATCCCCTCATTTGGAATGGCACTCATGCCCTCA ACTACTTCTGGAATACTTTATCCAGGTACTCCTTGTTTTATTCTCTATAGAGAATAATCCAGGTTTCTGG TGAGAAAAGAGCTGTTGCTTGGGAGTGTAGAGTTGGGGCAGGACCCAGGGGTTGTGACTGCTCCTCCAGT GGTTTTCACTCTGTCTTCAGTATTTTAGCTCCCCTTGTCTACCTGCTGCTCATCTCCTGTTCCAGAAGTA CCAGATGCTATAAGTTCCTCATGATTTTAAGGATTCTGTAGTATAATCAGTTGACTCTTCACTTTGAGAC AGTGGCAGCTTAGGATTCTGCTTTTGTGGATTTGCAGTGTCAGTTACCACCTGCCTGTCTGTTTTTTAGT TTCAAAAACTTATGGTTCTATTCCCTCTCTCCTGTTCTCCTCCTTGTGGGTTTATATTTAAAAACAAAGA AGTCTTTACTGTAGACAGTGGGATTCCAGGAGGTTGTACAGTTGAGTGCATATGTTCAACCAACTATATT AACTTGGAAGGCTCCTCAGTCAGCTTATAGAGAGCCTCACTCACCTTGGCTGGGCAGATTGTTTGGCTTT GGAAGAAGGTTTTAACAGTAAAGACAGACACCAACATTAAGAGGAGAAAAGAGAGCTAGAACAAAACCAT AATGATAGAGCAGAAGAAAATATCTACCATAGCCACAGAGATAAGATGTTTGTGCATATGTAAGCATCAG GATGCCACAGAAAAAGACCATTTTGAGACTAAAAGAACTCTTCAAAATTAAAAATGATAGCCAAAATAAA CATTTCAGTAAAAGAATTGGGAGATACTTTTCTGAGATATAGGTAAATAGAAAGCAGAACCAAAGGATAG AGCTTGGTAATATGAGCAGAACAGAGATTTAGAATGATCAGTTCAGGAAGTCCCAGCATCCAATTAAAAA AAATTTTTTTTTAAAGAAGAGCCGGGTGCAGTGGCTCACGCCTGTAATCCTAGCACTTTGGGAGGCGGAC GGGGGAGGATCTCTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCTCCTCTCTACTA AAACTGCAAAAAATTAGTCGGGCATGGTGGTGGGTGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAG GAGAATCGTTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCCGAGATCGTGCTACTGCACGCCAGCCTGGG TGACAGAGCGAGAATCCATCTCAGAAAAAGAGAGAGAAGAAAACTTTGGTGGAGGAAGAAATTGTGAAAG AAATAATACAACAAAAAAAAAATCCTAGGATTGAAGGATATGAGTTTCCAGATTGAAGGGGCTTACCTGG TGCCCAGCTAAATCAATAAAAAAGAATGCCACCAGGTCTCAATATTGTAAAAGTTTATAGTACCAGGGAT TAACCTTTCAGAGAAAGAAAAAAATGAAATCACATTAATAAGGATTAGAAATCAGAATGCTGTTAGCTTC TGAAATACCTTCAAAATTGAGAGAAAAAGGTTTTCAACTAGAATTCTATAGCCAGCCAACTTGTCTATCA AATATGAGACACTTTCAGATATGCATGGACTCAAATTTCCTTCCCATATGTCCTTCCTCAGTTAATCACT GGAGCATGTATTCCACCAAAATGAGAGTAAAATCATGAAGGAGGAAGACCGAATCCAGGAGACTGGGGCC TGATCATGACCGTTTTACAGGACCATGTCCAGGGAAAGTGTCAGGATAACAGGCAGTGCTGAGAGCAGCC AGTCCAATCTGAAGCCAGGGAGAGAGTGCTCCAGAAGGGAGCTCTTCTGGAAGATGAGGAATAATCCTGG TGGATTCTTTGCATTTCATTAGTAAAAGTTATATTAGGCATTGTTTCAGAGCTGTTAGAATACATTTAGG AAAAATTAGCAATAGACACACAAAAAAGTGAGGAAGAGAAACAGAACAATTAAAACTTACAAGAAAGGAA ATATTATCATAGTATACTCTGTGGCTCAGCCATGAGTAGTACTTAGGTAGTCATAATGTTGAAATCAATT TTGAAAACAACAAAAACAGTTACATATTTATTTTGAGAGCATTGAGGAGGAGGGAAAGGATATATGGAAG AGTCCTCAATCCTCACTTCCCATTAATAGTAAGTTAATAGATGGTGTCTATAATTTATAAATCAAGAAAT TAAAAGCACAGGGCATATTCTTTAGAACTATAGAGGCAGGATAACAATTCAGCTAACAGAATTGGAAGCA GCTGCCAGAGTGGTTGCAGTGGGGAGGGATGGGAGGAACCTTTAGTACCGTATTGACTTTTTAAACTACC ATATTTCATTGGATCTCAGATGCCGTTAGATGTGTGCTGTACTTCTATTTTATATACATCTGAGAAAGAA AAAAATGCCAAGTAAACTAACATGCATTTGATTAGACGATGGTTCCCAGTTTTAGATATTAAAATATGAA AAGTCCTTTTAAGAAGCAGGGAAATACTGTAAGTGCATAAATTACTTTGATTAAAATAAAACATTTAAAT GTATTCCTCTTTTATTATGATTCTCATTTTCTCCTCTAAAATCAATCTTCTTGTGTGTACACATGTGTCC TAACGCCTGCTCTCAATCACTTTCTAGTCATGCTGAGAATGCATAAATAGGAGCCTATCCCCATTAACAG GATCCCACAGGCAGTGAGAACCCAGGTAGTGAATGAAGGGGCAGCCCTGAAATCGAAAGGCTCGCTCTTC AGGGAAGCTGCCTTATATTCTCCCCATGCCCTGGACACTTTCTTTTCTGTATTTAATACCGTGTTTTCAG CATCTAAGATATAATGAGCTTCCTACAACAGTTGAGTAGGATCACATGCTTTGTTAAGGTAAACCTATGG AGTGCCCTTAGTGTTGCTGTGCTGTTTTCTGTAAACTTGGAAAAAAAATGCAAATCTCTGATGGAGTTAC TAACCACCTTAGAAACACATAGAGCAAAGTTATGTTGTCTAAAGGAAAATAGTTTATGCTTGACTAGGCG TTTAATTTTAAATATTCTGTTCATTATTAGGGCCTTTATAGAATGTTTGGTAAATACTGAAGAGTTGAAA GAATAAATGAACATTGTTCGTAACTTCACTTCTTTTCATTTGAATACTTACTACAGTCAGATATATTTGC GGGTGTGTCTCTGAATAGCTTTGTGTCTTTTTTTCTTTTAAGATTATATTATAAGCGTTTTATGTCATCT AATGTTTGAAAGCATTATTATTTTTTTGCGGCACAGTCTTGCTATGTTGCCCAAGCTGATCTCGAACTCC TGGGCTCAAGTGATCCTCCTGCTTCAGCCTCCCCGGTGGCTGAGAGTACAGGCACGTGGAAAGCATGATT TTTTTTTTTTCTTCCTGAGACAGGGTCTTGCTCTGTTGCCCAGGCTGGAGTGCAGTGGTACAGCATGGCT CATGGCAGCCTCAACCTCCCAGGGTCAAGCTATCCTCCCACGTCAGCCTCCTGAGTGGCTGGACCATGAG CACATGCCACCACGCCCAGCTATTTTGTTGTTGTTGTTGTTGTTGTAGAGATGGGGTGTGGTCTCACTTT GTTGCCCAGGCTGGTCTTGAACCCCTGGCCTCAAGTGATCTCCTGCCTTGGCCTCCCATAGTGCTGGGAT TACAGGTGTGAGCCACCATGCCCAGCTGAAAGCATGATTTTCTTTTCTCTTTTTTTCAGAGTCTAGCCCT GTAGCTCAGGCTGGAGTGCAGTGGTGCTTTCCTGGCTCTCTGCAACCTCCGCCTTCCAGGTTCAAGTGAT TCTCGAGTCTTAGCCACTCAAGTAGCTGGGATTACAGGTGCATGCCACCATGCCTGGCTAATTTTTTTTT TTTTTTTGTATTTTTTTTTTAAGATGGGGTTTTGCCATGTTGCCCATGCTGGTCTCGAACTTGGCCTCAA GTAATCCGCCTGCCTTGGCCACCCAAAATGCTGAGATTACAGGTACGAGCCACCACACCCAGCCTTAAGC ATGATTTTTTAAATCAACTTTGGTATGGTATAATTTGCTTACAATAAAATTAATCAATTTTGCTAAGTTT TGACAAAAATCCCAATCATAATAAAGAACACTTCCATCATCCCAAAAGTTCCTTTGTGTCTCTTCCCCCA CTTCTGGCAACCATCGATCTGCTAAAAGCATGCTTTTTCAGGGGGTGTAATAATAGTTATTCTATAAAAT ATATCCCTTTGGTTGAACTTTGGGTTATTTCCTTTCTTCTTTCCATTACAAGCTGTGCTGTGCTGAACAT TGTTGTATGTCTGTTTCTATAGGATAAATTCTTAGAAGTGAAACCATGGATCACATAACAGGAATCTTTA GACAGTTTTAAAAATATTCTTGGCCGGGTACAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTA AGGCAGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTGGCAAACATGGTGAAACCCCATCTCTAC TAAAAATACAAAAAATTGGCTGGGGATGGTGGCGGGCACCTGGAATCCCAGCTACTCGGGAGACTGAGGC AGGAGAATTGCTTGAATCCAGAAGGTGGAGGTTGCAGTGAGTCGAGATTGCGCCACTGAACTCCAGCCTG GGTGACAGAGTGAGACTCTGTCTAAAAAAAAAAAAAAAAAAAAAAAAAACAAAACAAAACAAAAAACCCA TGGGAGGCTGGCACATTGGCTCACTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTATCGCCC AGGCTGGAGTGCAGTGGCGTAATCTCGGCTCACTGCAAATTCCGCCTCCTGGGTTCACGCCATTCTCCTG CCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCGCCACCGCGCCCAGCTAATTTTTTGTATTTTTAG TAGAAACGGGGGTTCACCATGTTAGCCAGGATGGTCTCAATCTCTCGACCTTGTGATCCGTCCGCCTCAG CCTCCCAAAGTGCTGGGATTACAGGCTCACTTCTGTATGTACGTCAAGACATACAACAGTGTTCAGCACA GCACAGCTTGTAATGGAAAGAAGAAATAACCCAAAGTTCAACCAAAGGGTTATATTCTATAGAATAACTA TTATTACACCCCCTGAAAAAGCATGCTTTTAGCAGATCGATAGTTGCAAGAAGTGGGGGAAGAGACTCAC CACAAAGGGCACAAAGGAACTTTTGGGGTGATGGACATGTTCTTTATTATGATCGGGACTTTTGTCAAAA CTTAGCAAGATTGACTAATTTTATTGTAAGCAAATTATGCCATACTAACACGTTGATTTAAAAAATCATG CCTTCAGCTGGGCATGGTCATGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGAGGATC ATTTGAGGCCAGTAAGTTCGAGACCAGCATGAGCAACAAAGTGAGACCCCATTTCTGTAAGAATATTAGC CAGGCACGGTGGCACGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGTGGCAGGAGGATCCCTGAGCCTAG GAGTTGGAGGTAGCAGTGAGCCACGATCATGCCACTGTCCTCCAGCCTGGGTGATAGAGTGAGACCCCAT CTCAAGAAAAAAAAAAAAAGAAAAAAATTCTCATGGACTTTCTTTAGTTTGTCTTTTTATACTCTGTTTC TGGTCCAGGGATGGATTTGACACCTGAGGCCTTGATAGGAGACCTTAAGTCAGCCTCAGCTGCTTGGCAG TCTCCAGGTCTCCCTATTTTTTGATGACCTTTGTTCCAAAGGACATTTTTCCCTGCCTGCTGCTCTGCTG CATAGCTTATGTTTCATTTTTCCATTTTGAGGCTACACCTAGTCTTTTGTTGAGGAAATATTTGTTTCAG ATTAGCTTGTAAACTTGATATAACCATTTTAAACAGGGAAGGTATAGGATTGTAAAATGAATGGCTATTT CTTTATGTACTAGAATTGTTTCAGACTTGGGCTGGCATGGTCCCGCTTGTTCTTTGCTATCAGAGTTCCG TGGCTGGCACTGAGTTGACACTCTGAAGTATTTAATTCAGTTGATTACAGTTTGCATTTCTTGACTTTCA TTGCATTTTACAGGTGGAAGAGATTAGAAACTCATGATGTTGTGATCGAGTGTGCCAAAATCTCTCTGGA TCCCACAGAAGCCTCATATGAAGATGGCTATTCTGTGTCTCACCAAATCTCAGCCCGCTTTCCTCATCGT TCAGCCGATGTCACCACCAGCCCTTATGCTGACACACAGAATAGCTATGGTAAAAAGTGTCTTTGGTACT TATCTGTTTTGCAACTTTGTCTCTGGAAAACATTATTTGTCTTTGTTGATTTTCTTTTCTGGAGTAAGAC TTAGTTCAGTTCCTAGGGATTTTTCCCAAAATATCTTAAATTTGCATGTCCCTCCATTTTCTTCTAATTA ATTTCTCCTTCAAGTTTAATTTAGATGTCCTTGGTCTGCTACCTGATTGTATGCCAACAGAGTTGGTGAC GTGTCTCCAACACTTAAGAAAGAAAATGGGTTTAAGTATTTGACTTCCAGACTCTACCTCATAAGGGAAT CTTTCTGATTTTCAGACATTTAGAGTGAGGCTCTTGTGTCTGTAGCACTGACACAGTTTGAATGAGTCGG AACAATTTAGAATTGGATTCATATAAAAATCTAGGCTTTATTTGTGGGTTGCAGCCACTGAAGTTGTCAT CTGTATTGTGCTTTTTTAAGTTATCTTGAGGCTTAATGAGACATCAAACCTTATTGAACTTTATTTCAAA GGAGCATTTAGAGAAACTCTGAAGTGTTACTTTGTCCCCAAGGATGTCAGTTAAGTCCCTCAGATTTTTT AGGTACAGAGAATTGAATATTATCAAATGGTCTAGAGGACCATCTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTAACCAGAATAACCTAAAACCACACACTAACCCCCTGTGTTCTTCTCTTCCATTTTAGGGTGTGCT ACTTCTACCCCTTACTCCACGTCTCGGCTGATGTTGTTAAATATGCCAGGGCAGCTACCTCAGACTCTGA GTTCCCCATCGACACGGCTGATAACTGAACCACCACAAGTATGGTGTCAACTAGTGTGCCTGCTCTCTCC TCTGCTTTCTGGTGAAGCTGACCCTTTGGGTCAGATTTAGTATGTGGTTGGGAAAATTTCACACTGCTCA TTTCAGGAGTCACTTTTAAGGATCCATGATATTAGCAAAGAAAGTTACTGTTGCCTCTTAGATTCATCTT GAAGTCTTGATTTACAAAATGCAACTTGTTTCTTGATACGCTTTTAATAAGATGCCTTTTTCTAGATGAA AAAGCTAAATTTAAGCTGAACACTGGCCATGGATATAAACCTCGTGGATGACTTAGCATTCCTTTGCCAC TGCTGATGTACTTTATTAACTTCCCAGGCTACTCTTTGGAGCCCATCTATGGTTTGTGGTATGACCACTC CTCCAACTTCTCCTGGAAATGTCCCACCTGATCTGTCACACCCTTACAGTAAAGTCTTTGGTACAACTGG TATGTATGTCTTAGGTTGGATTTGATTAGTTGGTTTTGGCCTGCCTTTAATGGCAGGAGGAGCTCTCTTT TAGATCTAAGGGACCACTTGCTGTTGTAAACTTGTTTTTGACACTTATTGCAAATCCCTGGGGCTTTCAG AATGTGTAAAGTGAACCTAAAAACAAAAAAGAGAGAGACTGATCTAGATCCCCAGAAAGTTAACTCTAGC AGCTTTATTTATAGTAATAGTTATAGGCTGAAAAAAAATCGGCAGTTTTTCTAATAGTTGGGCTCAGTGT TCATATATGTTCTGCCCTTGTCTCTAAGCAGGTGGAAAAGGAACTCCTCTGGGAACCCCAGCAACCTCTC CTCCTCCAGCCCCACTCTGTCATTCGGATGACTACGTGCACATTTCACTCCCCCAGGCCACAGTCACACC CCCCAGGAAGGTGCGATCCAGCTCGTCTGCTATCCCTCTGCCCAGGCACAGTGACTCACTTGCAAGCCTC ACTTTGAGAAGCCTAATTATGCCAGATAGAATTCTGACCTAAAATGCAATGGGTTTGAATCAGAATAATT GAAAATGGACTAACAAGCTGCTCTCAAGGTGTGATCTGCCGACCCCTGGGTGGTTCCAAAACTCTGCTTT GGCAGAACTCTTGTGGGGAACCCAGCAGGTCAAACCTACTCTCTTGATTTTTTTTTTTTTTTTTTTTTTG GAGACAGGGTCTTGCTCTGTCGCCCAGGGTGGAGTGCAGTGGCACGATCATGGCTCACTGCAGCCTTGAC CTCCCAGACTCATGCAATCCTCCTGCATCAGCCTCGCTAGTAGCTGGGACTACAGGCATGTGCCATGATG CCTGGCTAAGTTTTTTTTTTTTTTGGTGGAGATGAGGTCTCACTATGTTGCCCAGGCTAGTCTTAAACTC CTGGACTCAAACGATCCTCCTACCTGGGCCTCCCAAAATCCTGGGATTACAGGTTTGAGCCACCACACCT GACCAAACCCACCTTCATAGTAACACTAAGCTGTCATTTGCCCTTCCCACTGCATTGGCATCTGCAATGA TGGCACAAATACGACGGGGGGTGAAATGGTGGCAACTTAGCCTGAATCAAGGCAGGCATTGAAGTGTCCT ATCCCAAGAGGCCTTGCATTCTTCCCTGACATCTTCTCTCCATTAAAAACAATAAAAACTAAAAAATTTT AAAAGTTGAGTGTTCTGTATTAAGCAGTAACCATTATTAATTTTATTAAATCTTAGCCCTTGAGAACATG TATGTGTAATATTCTTCGTGGCAAAATAGAAAATATGCATAAGGCACATGTACTGCATACCAGGGTATGA TGGTGACCTCTGGCCCTCATGCAGTTATTTGAATTGAGAGGTGAAGTAGCTGCCTTTTTTCATGGAATGC CAGTTTTATTTGAAAGAACTGCTGTCTTACAAACTGGTTATTCAGACTTGGGTGTTTGGCAGGCAGCTTC TCAAATGATGAGCTGAGTCTGTCACTTCAAGATAAACAACTGACAGTATTTGTTGCCAACAATAAAAGTC AACTCTCAGGTGGAAATCAAGATATTAAAAAACGTGTATATACTACCATGAACTTGATAGCTGCCCCAGG ACTTTTATGATGAGACCGAAAAGTCTGTGGAAGCTTAGTTAGTAATTTGAGTTTTTGATATTGTATAATG AAGTGTTTCAACATTTGGAATATTTGAATAGCTTGAGGAGCCAATATTTTCAGAGTGTCCAATGTATGAT ACGTTGCAGAATCATGCATAGGTAAAAAGTACATTCAAAGTACAAAGCAGGCTGGGCGCAGTGGCTTACA CCTGTAACCCAGCACTTTGGGAGGCTGAAGCAGGTGGATCACTTGAGGTCAGCAGTTGAAGACCAGCCTG GCCTACATGTTGAAACACCATCTCTACTAAATATAGACATTAGCCGGGTATGGTGGCAGGCACCTGTAAT CCCAGCTACTTGGGAGGCTGAGGCGGGAGAATCACTTGAACCCAGGAGGCGGAGGTTGCAGTAAGTCGAG ATCACACCACTGCATTCCAGCCCCAGCCTGGGCAACAGGGCAAGACTGTCACAAAAAAAAAAAAAAAAAG TGCAAGGTAGACTAGTGGGTTTTAACACAGGAAAAGCTCATTGATGTGGTTTCAAATTTCACTTTGTAAC TTTAAGAAACTAACACTTATCAAATTTTGGTGTAATAACAAAGATGATTATTTGAAAAGTCTGTCAACAT ACGTTTACTTTTTGCGGCTGGGCGTGGTGGCTTGCTTCTGTATCCAGCACTCTGGGAGTCCAAGGGAGGT AGATTGCTTGAGCCCAGGCGTTCAAGACCAGCCTGGGCAACATGCAAAACCCCATCTCAACTAAAAAAAA AAAAAAAGCCAGGTGTGGTGATGTGCATCTGTAGTCCCAGCTAATCGGGGAGCTGATGGAGAACGGCTTG AGCCCAGGAGGCAGAGATTGCAGTGAGCCATGATCACGCCACTGCATTCCAGCCTAGGTGACAGAGCCAG ACCCTGTCTCAAAAAGAAAAACAACAACACATATGTTTACTTTTGCAATTACATATCTGTGGGGCCCCAG ATTTTCTTTATACACTTCAGTCAAAATAACATATTGCAACAGACTGAATGTAGAGGTAGATATGAGAATC CAGCTGTCTTTCATGAAGCCATATATTAAAGAGATGGCAAAAATGTTCCATTCTTCTCACTAAATTTATT TTTATTTCGGGAAATATAGTTTTTTAATAAGAATATGTAATTTACATTAACTTGTAATGGGCTTGCTATT TTTAAGGGAATTAATATTTTAAAAATTTCCTGGTTTTCTAATATAATAATTATGCCTCGTAAAAGCTCTT GGGATTCTCCAACTTTCTCATTATTATTATTATTTTGTGTGTGTGAGACAGGGTCTCACTCTGTCGCCCA GGCTGGAGTGCAGTGGCACAATTGCAGCTCTCTGCAGCCTTGACCTCCCTGGCTCAGGTGGTCCTCCCAC CTCAGCCTCCTGGGTAGTTGGGACTACAAGCACCAGTCACCATGCCCGGCTACTTTTTAAATTTTTTGTA GAGATGGGGTTTTGCCATGTTCCCCAGGCTAGTCTCAAACTGCTGAGCTCAAGGGATCCACTGGCCTTGG CCTCCCAAAGTGCTGGGACTACAGGCGTGGGCCACCACGCCCAGTCTGCAGCCATTTTTTAAGACTATAA AGAAAGCTGCTGGGCGTGGTCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCATCTGAGGTTGGGAGTT CGTGACCAGCCTGACCAATGTGGAGAAACCCCGTCTGTACTAAAAATACAAAAATTAGCCAGGCGTGGTG GTGCATTTCTGTAATCCCAGCTACTCTGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGG TTGCAGTGAGCCGAGATTGTGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCCACCTCAAAAAA AAAGAAAAGAAAACATCCCAACAATTTGAGAATCACTGCACTCGGCTGACCTTTAAACTACTTTACAATA TGCTCGAGAACATGTGCAACATTTTTCGTCTTGTGATATAAATGATACTTATCTTTTCAGGAAGAGAGAA TGGATTCTGCAAGACCATGTCTACACAGACAACACCATCTTCTGAATGACAGAGGATCAGGTAAAATTTC TGCGTTACTACAGGCCTTGCTTGCCTCTTCTAATTGGGTTATATGTGTTTAAGAAAAGAAAGTTAAATGG AAACAAGGAAATTCTGGGATATCCAAAATACTGAGGCCTAAACATAATGAAACGAGTAGTGAATTCTAAA CACCAACCTAATAATATCAAAAACAGTTTTTAAGCTATTGCAGTGAAGTACCTGTATTCTGACTTGACTA TATCTCTTTTCAGAGACATTAAGAACTGAGAATTTTATTTGCTATGGGATTATTTTTGGTACTTTTAGTT ATATTATTTTTAATATTTCAGTCTTTTGTAGTATCCCCAGGACAGAGCCATGTCCAGCCTTCTCTGTTCA GCATGAAGAGTTATTACAGACATATTCTATACAGTGTAAGCAGTTTTACACTTACAGGGATTACACTGTA TTTCTTTGACTTCAGTTGTCTTTGTTTCTCTTCAGAAGAGCCACCTGGCAGCAAAGGTTCTGTCACTCTA AGTGATCTTCCAGGGTTTTTAGGTGATCTGGCCTCTGAAGAAGATAGTATTGAAAAAGATAAAGAAGAAG GTAATGTATGTGGGATTGCTATGAGTTGATAAAACCTGACCCTCGCTCTGCTATAAATCTGGGATTTTGT GCCATTGCTCACAGGCTTGCTGGATTTTTCTTCTCTTGAGGTAACAAGATGGGTGGTTTAGTCTGGGACC TATGCCAGGTAAAGTGATGCCACTTTTTTTTTTTTTTTTTTTGAGACAGGGTCTTGCTCTGTCACCCTGG CTGGAGTGCAGTGGTACGATCATGGCTCACTGCAGCCTTGACCTCCCAGGCTCAAGCAATCCGCCCACCT CAGCCTCCTGAGTAGCTGGGACCACAGGCATACACCACGATGCTCAGCTGATTTTTATTGTATTTTTTGT AGAGATGGGATCTCCCTATGTTGTCCAGGCTGGTCTCTAACTCCTGGGCTCAAGTGATCCTCCCTCCTCA GCCTCCCAAAGTTCTGGCATTACAGGCGTGAGCCACTGTGTCCAGCCGGATGCCACTTTTTCTCCTCTCT CTGAGTGACACTGGCATGTGGCAGCATGCCACCCAAACTGCCTAGTCTTTCCCAGGTGGAATACCGACTG CCATTTCTTTTGTTTCCTCTCTTCCTCTCAGCTGCAATATCTAGAGAACTTTCTGAGATCACCACAGCAG AGGCAGAGCCTGTGGTTCCTCGAGGAGGCTTTGACTCTCCCTTTTACCGAGACAGTCTCCCAGGTTCTCA GCGGAAGACCCACTCGGCAGCCTCCAGTTCTCAGGGCGCCAGCGTGAACCCTGAGCCTTTACACTCCTCC CTGGACAAGCTTGGGCCTGACACACCAAAGCAAGCCTTTACTCCCATAGACCTGCCCTGCGGCAGTGCTG ATGAAAGCCCTGCGGGAGACAGGGAATGCCAGACTTCTTTGGAGACCAGTATCTTCACTCCCAGTCCTTG TAAAATTCCACCTCCGACGAGAGTGGGCTTTGGAAGCGGGCAGCCTCCCCCGTATGATCATCTTTTTGAG GTGGCATTGCCAAAGACAGCCCATCATTTTGTCATCAGGAAGACTGAGGAGCTGTTAAAGAAAGCAAAAG GAAACACAGAGGAAGATGGTGTGCCCTCTACCTCCCCAATGGAAGTGCTGGACAGACTGATACAGCAGGG AGCAGACGCGCACAGCAAGGAGCTGAACAAGTAAGGGACTGGGGCACTCTCTTCTGTGTTAAATGGTCCA TTTTATTGTGAAGTACAGAAAGTGTAAGAGAGGAACAAGAATCATTCTTCACACTCCCACCTTGAGGCAG CTGGTTCTCTGCTGTTTGTCAGATGTCCTTCTAGGCTGTTGCATCTTCATATATGTGACCATGTGTGACC TCTGTGCACCTAAATTGGGATGATTCCTTAGCAGTCCATTTCAAAATGAGTCTTTTTATATAGGCCATTT TATGCCTCTGTTCTATGAGGACACTCAAATGCTTTCATATGTGCCCTCTGCAAGCTGTAGGCTGAAAATG AGGTTATGGTATTTCAAAGAATATAAGAATATTTGTCACAGTGTTTCCCTCTCTAGCTACAGATTATTAT TATTATTTTCTATTTTGGTATCATAGTTCATTAGGTGGAGATAAAATCATCAGCATTTTATGCAAGTTCA GATGGCCTGACATCCCCTCCAGACCCCCTGAGGCACCCAAGTTTTCATAGAAAGGACTCTAGCTGAGAAA CGGTTTCCCATCCGTCTTTTATTAGCTACTTTACAGGTGCTTGGGGAATATTTTTATTTTTCTTCTTATA TACTATGCTATGGTGGAATTTGACAGGGATTATAGTATTTAAGCTCCCTCTTTTTAAACGAGATTTGGTA TGATAGGCTTAGGTAAATTACCTACTTTTTCCTTAAATCGGAGTGACATAGCTTTACAACAGAGTGTACT CCCTGTATATTTCAACAGACAGGGTTGAAAACGGCTCTCAGTGTGTTTGACTACTCAGTTTCTCTGGAGA GCTGGCCCCAGAAACGGAGGCCACGGTGTATGCAGTGCAGCTCAGCCTGCAACCCTCTCCGCTCTGGATT TGTTTTTTAAAGGACTGTGTTAAGCTAACAACACAGGTCCTAGGCAGTGGGGCGAGGGCCGCCTCCCATT GTGTCCAGTGTAGGCTTCTCCTCTAACTCTCTGTGGACCTGGAGTTTGAAACATTCTTATGCCATTGCAG ATTTTGACCACAAGGAAGTGATCTAACTTTGCTGCAAATAAAAGTCCAGATACGTTTTTTTCTTGGTAAG ATCGGTAACTTTGTTACTCAAAAACTTTCTTCCTAGGTTGCCTTTACCCAGCAAGTCTGTCGACTGGACC CACTTTGGAGGTAAAGTTGTTACTTTAGCTCCAAATCCAGCCCACATGGTTCCTGCTTGCTTGTTGCCCT TTCTGTCCTTGAAGGAGGTGCCCTCTGGGAAACAGATCTCCCCTTGGCTATTGCTCCGGCCAGGCTATCT GCTTGGCTAAAGGATCTCAAGTGTTGCCAAGTCAGCATTTCTTATTTTTGAAAAGTGGCAAGTACTATGC GCTTGAGAGTATAAGTGCAAAATACAGACTTCCTGCCAGGCTTCCCTGGAGAAGACCAGAGTGAAGCATC TTCCTGGGGGAGAACACACAGCGAAGGAAGTGTCTTGAGAAACAGGGCATCTGAAATGCGTGATCTAGAT TTGTGGGGAAAGGAAAGCAGGCTCTCAAAGAGTCATCCCACATGATATGACCTTTTGCATTCCTTCACGG GGGAGACACATAGTCCATACTTTCCCCCCTGCTGTTGCTGGGAGTCAAGTGGTCATTTGCAAAGAGAGTG GTGATTTGTTTTTAAAGAATTGTGTTTGTTAAGCTAACAACACATGGGAAGGGGGCTTGATTGAACCATC TGTAAAAGGCATTTCTGCCACCCTCCCTCTGCTTTACAATCAGGCTCTCCTCCTTCAGATGAGATCCGCA CCCTCCGAGACCAGTTGCTTTTACTGCACAACCAGTTACTCTATGAGCGTTTTAAGAGGCAGCAGCATGC CCTCCGGAACAGGCGGCTCCTCCGCAAGGTGATCAAAGCAGCAGCTCTGGAGGAACATAATGCTGCCATG GTGAGGACTGGGGAGGGGACAGGTGGAGCTTGCTTTTTGTTTTGTTTTGGGTCAGCATGATAGCTTATAA AGCACAGCAGCCGAGGAGGTCAGAGTTCCCAGTCCTTCCCACTCCTTTGGGCAGGTCGCTTGAGATTAAG ACATGAATGGTGACACCTCGGAATTCCCTCATAATTCTCAGAAACCGTGGGGACAAGTGATTTTGTGTGT GTATGTTTGCATGTAACTGGCCATGATGATGAAGGGTCAGAAGATGATTTTATTTCTCCAAATGTAAAAC CAACTCTTGTAAAGCTATTTCATGGCACAAAACTGAAGCGTGTATTGTACAGCGGGTGTGAAGCCAGTCA GGCCTGGAGTTTGAATCTTGGCTCTACCAGTGTTACCTTAGAAAAGTAACGTGGCCTCTTGAAGCCTCTG TTAGCCATGCTATAAAATGGAAATAACAATAGCAGCACCTGCTCTTTAAGTTGTGATGGTTAAAAGAAAT TATGTCGGTAAGCCCTTGCTGAGCGCCCAGCACACTGCAAGCATTCAGTAAATGCTCATCGTTTCAGTGA ACTTAGTACCATGTTTGAGAGATTTTATTCCAGTGTTGGTAGTCAGACTTTTGAAAGTATTGGAAGCAAA CTGATCCCTGAGAAGATTTATTTAAGCAACTTAAGATCCATTTGCTTAATGTAAAATTTGGAAAACCTTG ACCTAAGGCCAAGTAAGACAGTAGTGAGCTCTAAGAGTTTTGGTCTGTAGTTAGTTACATTTTCAGGGTA GCTTATGACTATTCAGATGAAATGTTCGCAGTGTGTGTTAAATTGCCTGTGTTGGAAGACAGCTAAAATG ATGACATTTCTGGTCTCTGCTAGAAAGATCAGTTGAAGTTACAAGAGAAGGACATCCAGATGTGGAAGGT TAGTCTGCAGAAAGAACAAGCTAGATACAATCAGCTCCAGGAGCAGCGTGACACTATGGTAACCAAGCTC CACAGCCAGATCAGACAGCTGCAGCATGACCGAGAGGAATTCTACAACCAGAGCCAGGAATTACAGGTAT AAACTGCAGCACCAGGCAAAGCCAACTGCGAGAATGCCGGAGAGCAGTGGGGAGGGAGGCAGTCAGTTTC CCTGGGTGTCCTTGACTTGTTCAGCTTTACTAAGCTGAATGCTTTTCTCTCTGAAATCATGGCAGAAATT CTTCATGGCAGGTGAATCTTACTTAGGACAGAGGTTCCCCAACTTTGTTGGTTCATATAGTAGCTCCCTT AGTGTCTCAGTCATTTTTTTTTCTGCAGCCAAAAGGAAACAGTTAACAGTTCTGCTCATTAAGTAGATCT GAATAACTTAGTGAGTACGAATGTCCTAAGAACTTAGTAGCTGTTCACAGATAATACACATAAATTAATT TTTAAAAAAATAATTGCAATTACTAATGCCTCGTGTGCACCTATTGGGCACTGCATGGTATCTCAGACCT TGAAATCAGAGTGGACAGTGACACCCTCATTTCCTGTTCCACACTGGTTTTCCTTGTGGTGCTTTGTATC ACTGCACCCAAAAAAACCCGGCTTCACAAAGACGTCATCCACAGACACAGCATCATTTCCAGCCAGTTAG TAATTCACAGAGTGTCCAACAGATGGCGCTGCGTCTCCCTCGAAAATTCAGAATCTTTCTGCAGCATCCC TGTGAGTTTGCTGTGTAGCCTCAGGGCTCTTTGGTGCACAGTTTGGGAACTGAGGATCTAAGGTCTCTTT TTTTCTTTTGTTAAACAGTAAGGAACTCAGAAATCAACCATAACTTACTTTTTAAAACTAAGACATCAAA TTCTGAGGGCCCAAGAAAGTAGAGCCGTTGAGCTAAGGCATTCCCAGTCCTCTGTGGGCTGGTGGCTAGG TAGGCCTGTGATCTGGCCTGTTGGTGTTCCTCAAACTTCATGTCCACGTCTCTTTGGGCAGACGAAGCTG GAGGACTGCAGGAACATGATTGCGGAGCTGCGGATAGAACTGAAGAAGGCCAACAACAAGGTGTGTCACA CTGAGCTGCTGCTCAGTCAGGTTTCCCAAAAGGTAAGAAGAAATGAGGCAGACCTGAATCTGCTGAAACA CCATTTGCTAACATTCTTCCTTCAGACAGGTTAAAGAAATAGATTACTTGAGTGTCTGTGTCATGGGTTC CCAACAGGAAGTGGTTCTGCTGCCCCCATAGTCCCTGACATTTGGCAATGTCTGGAGACATTTTAGGTTC ATGTTTTTGGTGCTGCTGGTATCCAGTGGGTAGGAGCCAGGGTGCTGCCAAATATCCTACAATGCACAGG CAGCCCCCTGCAACAAAGAAGTATCCATCCTAAACCCTGCTCTATGTGTATCCCATGGAACTCTTTCTTC ATACCTTGTTTACATAAATGTCAAAAGTTTGTTCAGGTTTTTGAGCGTGATTCCTCCTTCTTTGGGAATC ACTGCACTTCATACATCATTTTGTCAAGAACGGTGAGTTTTCCCTAGGGCTTTATGCCACTGGGCCTTGG TGGTATACCTGTCCACCTTCTCCAGGTGTTCTGTGGGTGGTCAGTTTGATGGACTGCATTTGTGCTGTCC CCTTTGCAAAGCACAGTTCTGAAGTGTGTTTCTGTCTATTTTTGTTGTCCTTGGGTACCATCCTCCCCAC CTGCCATTATGTCAGGGACTGTGAACCCATGGGACTGGTTTATTTTGCCTTAACATTGAAATAGTGTGCT CCTAGCTGATTCCCTGTTTAATGACGTCTATGTGCTAGTTTTATGTCGTCGGATTTTTCACTTTGCTCAT GTTTTTTGGTTAGCTCTCAAACAGTGAGTCGGTCCAGCAGCAGATGGAGTTCTTGAACAGGCAGCTGTTG GTTCTTGGGGAGGTCAACGAGCTCTATTTGGAACAACTGCAGAACAAGCACTCAGATACCACAAAGGTAT GCCAGGGCTCGGGAGCCAGACCTTAGTGGGGAAAGCGTTTCAGACCCAGACAGTATGTCTCCCGCATGGC ATAGAGAATGGCTTGATGACTTATTTCCTAAAAGACGGAGCGGCAGTCCCACTACTCCGTGGTCCAGCTA TACAAGCACTTTCCAGCCACCATGTGAGCTTGTTTCTCCTATTGGGTTGCTTTGAAGTTAACTCACACTG AAAGCACCTAATGGTAGTTGGTAGAGAGTAGGTGTAAAGTGTTTCCTTTCTCTTCCCTAGGCTGCCTTTC AAAGAGGGAGAGAGAAAAAGAAGGATGGGGGACCAATTCTGTTTAACATACCTCTCAGGACCATGGATAT AGAGTGCTGTACATACCATTTTTTTTTTTCCTTTTAATGTTGGATTTCTGCAGATGGTAGTTCAGTCCTG GCAACAAGGCCAGCATTGGGATGATCTTACATTAATTAGTGCCTCACCAGTGGTGTCGAGGCAGAAGTTT TAAGTCACTTTATAAATAGCCTCAGGTAATGTTAGTGAATGAGGTGGGAATTGAATTTTAATAGTAGCTG TTCAGATACTTCCTGTCACTAACTTCTCCATCACACATGGGCCTTCTTTTTGGGTTTCTTGGGCATGTGC TTTGTAAAGAGTCTTTTTCGGCCGGATGTAGAGAGGAGTCTTAGAACTGGAGAGAGTAATTTTCCTAATA GAGTTACTCTTTATTTCTTGGCTCCTCTCAGCTCTCAGATTCAGACTCCCTTTTTTAGAAGGATGTTAGG TGTGGGACTTTCTCTAGAAAGCAGCTATCACTTATTTTGGAGGTGTAATGACTGGGAACAGAAAGGGGGA GAAACAGATCCGAGGCACAAGAGAGCTCCTGAAAAAGCTGCTGAAACGTGCCTGGGCCATCTCCTGAGAG AAGCCTAGATGGGCGGCCTCCAAGGAGTCCTTGTGCTGTTTGGGACCTTGAGTAGCTGCCTCTCCATGGG GCCCTGTTTCCCAGTTCATAAAACGGGTGATGCAGCTGAGTTGTGATAGTCAGGATGCCTTCAATTGTAG ACAACAAAAACCAAACTAGGGCTGGGCACGGTGACACATGCCTACAGTGCCAACTATTTGGAAGGCTGAA ATAGGAGGATTGCTTGAGCTCAGAAGTTCTAGACCAAGCCTAACAATATCCAAAAAAACAACAAAAACAA AAAGCACTCAACTGGCTTAACAGTGAAGAACTGTATTGTTTCACTTGACAAGAGGTTGTGAGGCAGGTGA GTTCCAGGTTGGTCAAGTTGGCCATTCAGGGACAGCATCGAGGAGCCAGGCTCTTTCCACTCTTCTGCAC TGCCTTGCTTATCCTGCAGACCTTGTCTTCCAGCTAGCTGCACTCATGGTTGCCAGGTGTGTGCCACAGG CACAGATATGACAGGCAGACACAATGATGTCCCCACAGAAGAGGAGAGCATCTCTTCCTATTCCTCAGCA AGAAAATCTTTCCCAGGCTGGACGTGGTGGCTCATGCTTGTAATCCCAGCACTTTGGTAGGCCGAGGCGG GTGGATCACGAGGTTAGGAGAACGAGACCATCCTGGCGAACATGGTGAAACCCCGTCTCTACTAAAAATA CAAAAAATTAGCCAGGTGTGGTGGCGCACACTTGTAGTCCCAGCTACTTGGGGAGCTGAGGCAGGGGAAT CGCTTGAACCCCGGAGGCGGAGGTTTCAGTGGGCCGAGATCACGCCACTGCACTCCAGCCCGGTCAACAG AGCAAGACTCTGTCTCCAAAAAAAAGAAAAGGAAAAGAAAACCTTTCCCAGATGATCCCACCATACTTCT CATCACCCCTGTTGGCCAGGCCTGTCCTGTGCCCATCCCTAGCCTAGTCATTGCCTCAACCCAGTCAGGA TTTGCTCCTGAACCTGGAGCTAGGGTTGCTCTTGTTCCATCCAAAGGAGGAGGAAGAGTGAGTGGTGGGG AATCAGGTGGGAACAGTTGGTAGGGGTAGCTGTAAGGATTAGTGAGAGTGCACGGATGTTCCTGGTTCAA TGCTTTGCATGATTATCCATGAATAAGTCCTGTTGTTTATGACGAAGGCCAGATAGATGCGTTCATCCAC CCTGTGCTGAAGTCGAGCCATTTAGCACAGCTGGAACAGCCGCATTATCCGAGAGCCAGTTCTGAGTTTC AATCAGTTGCGTTCTATAACAAGGAAGCATTGGGCTTACCAGACAGCATCAAGGCAGGGCGCCTTCGTGA AAGCTCATCTCCTTGCTGTTTATGGTTTATTATCTTTTTTAAAAAACAAATATATGGCAAGTTTTGTGTT TTGTATATTTTACCACGGTAAACATACACACACAAATGTAACACAGGCTTAAAAAAATACCCTTTCCGCC TTCTTTCTGAGCATTAGTGTGTACTTGCTCTGGGTTTCAAGCTGTTCCAATCTGTCGGCAGCAGGCCATC TGCCTTAGCACGATCAACAAACCTTGTCAGGGCATCCAGTCTGCAAAGGCTGCTTTGCTTGAGCAGACCT GCTCCATTGGCATTCCATTCTGTAGCCTCACCTGCGCTATTGTCAGGAGGGGGAGAAAAGGAGAAAGGAA AGCAAGTGACCTGCGGTACCACTGGACTGAAATGATAACTGGATAGTGGCGTATTTTCACTTGGTGTTTT GTATATGTATATGTTCGCATAGTTGATTGTACTATTCACACAGTCTTGTAGTCTGCTTTTTAATCTTTTT ACTGACACCATATCATTTTTTAAAAAGACTTAGAAATATAGGATGTATTTTAATTTACTTAACTGTTCCC CTGACATTAGACTTAAACGATGTTTCCAGGTTTTTGCTCTTATAAATATGCTGTGATGATTATTTTTGTG CAAAATCTCTATTTATGTTTCACATGATTTGCTTGGGGATAGATTTCAAGGAAGGGTTACTAGGATAATA CTACCAGCTTACTTTCCATAAAGTTGTACTAGTTTATATTTCTGTTATCAGTATACTAAAATGCCTTCTC AGTCCTTCTTACATTGTCTTTTCAAAATGGATACAGCATGTTTATTTTTTATAAGTACTAATTCCAGTCT TTTTTTTTTTTTTTTTTCAGGAAGTAGAAATGATGAAAGCCGCCTATCGGAAAGAGCTAGAAAAAAACAG AAGCCATGTTCTCCAGCAGACTCAGAGGCTTGATACCTCCCAAAAACGGATTTTGGAACTGGAATCTCAC CTGGCCAAGAAAGACCACCTTCTTTTGGAACAGAAGAAATATCTAGAGGATGTCAAACTCCAGGCAAGGT AACTTTCATCAGGAAAGGCTTTTGTGTTTTTATTAAGTGGAACTTCCTATATTCTGGCTGGTCTGTATCT TTCAGAGGACAGCTGCAGGCCGCAGAGAGCAGGTATGAGGCTCAGAAAAGGATAACCCAGGTGTTTGAAT TGGAGATCTTAGATTTATATGGCAGGTTGGAGAAAGATGGCCTCCTGAAAAAACTTGAAGAAGAAAAAGC AGAAGCAGCTGAAGCAGCAGAAGAAAGGTAGGAACAAAGAACTGATTCATGACCTTGGGACTAAGCTGCC AATTCCAGCATAAGGACTGTGTCACGTGGTGTGGGAAGCAGTTACTGCTGACTAGACAGGCTGCAACACT CAGCTCACTCCGTGTCAGAGACCCACTCTGACGTTCCTTTCCTCAAAACGCCCAGTGATCTCTTCGTGTT CGTGTTCCTGGCCTTGAGTCCCTCCATATGGCCACAGGAAGTGTTCACACTTAAGATTGCCACCTACTAT CCCTAGTTGTGATTTAGGTTTCTCTTGATGAGATCTCTTGAGTCCAGTATTATAAAACAGAGAGTGGGCT AGCGGAGTTCAGTGTCAGTGTGAGTGAGTGTCAGTGTAATTCCACATCCTCCGAATGTGGACAGTCCAAT CACCAGCTCCTTTTTTCCTCCCCGGCTTTCTTACAGGCTTGACTGTTGTAATGACGGGTGCTCAGATTCC ATGGTAGGGCACAATGAAGAGGCATCTGGCCACAACGGTGAGACCAAGACCCCCAGGCCCAGCAGCGCCC GGGGCAGTAGTGGAAGCAGAGGTGGTGGAGGCAGCAGCAGCAGCAGCAGCGAGCTTTCTACCCCAGAGAA ACCCCCACACCAGAGGGCAGGCCCATTCAGCAGTCGGTGGGAGACGACTATGGGAGAAGCGTCTGCCAGC ATCCCCACCACTGTGGGCTCACTTCCCAGTTCAAAAAGCTTCCTGGGTATGAAGGCTCGAGAGTTATTTC GTAATAAGAGCGAGAGCCAGTGTGATGAGGACGGCATGACCAGTAGCCTTTCTGAGAGCCTAAAGACAGA ACTGGGCAAAGACTTGGGTGTGGAAGCCAAGATTCCCCTGAACCTAGATGGCCCTCACCCGTCTCCCCCG ACCCCGGACAGTGTTGGACAGCTACATATCATGGACTACAATGAGACTCATCATGAACACAGCTAAGGAA TGATGGTCAATCAGTGTTAACTTGCATATTGTTGGCACAGAACAGGAGGTGTGAATGCACGTTTCAAAGC TTTCCTGTTTCCAGGGTCTGAGTGCAAGTTCATGTGTGGAAATGGGACGGAGGTCCTTTGGACAGCTGAC TGAATGCAGAACGGTTTTTGGATCTGGCATTGAAATGCCTCTTGACCTTCCCCTCCACCCGCCCTAACCC CCTCTCATTTACCTCGCAGTGTGTTCTAATCCAAGGGCCAGTTGGTGTTCCTCAGTAGCTTTACTTTCTT CCTTTCCCCCCCAAATGGTTGCGTCCTTTGAACCTGTGCAATATGAGGCCAAATTTAATCTTTGAGTCTA ACACACCACTTTCTGCTTTCCCGAAGTTCAGATAACTGGGTTGGCTCTCAATTAGACCAGGTAGTTTGTT GCATTGCAGGTAAGTCTGGTTTTGTCCCTTCCAGGAGGACATAGCCTGCAAAGCTGGTTGTCTTTACATG AAAGCGTTTACATGAGACTTTCCGACTGCTTTTTTGATTCTGAAGTTCAGCATCTAAAGCAGCAGGTCTA GAAGAACAACGGTTTATTCATACTTGCATTCTTTTGGCAGTTCTGATAAGCTTCCTAGAAAGTTCTGTGT AAACAGAAGCCTGTTTCAGAAATCTGGAGCTGGCACTGTGGAGACCACACACCCTTTGGGAAAGCTCTTG TCTCTTCTTCCCCCACTACCTCTTATTTATTTGGTGTTTGCTTGAATGCTGGTACTATTGTGACCACAGG CTGGTGTGTAGGTGGTAAAACCTGTTCTCCATAGGAGGGAAGGAGCAGTCACTGGGAGAGGTTACCCGAG AAGCACTTGAGCATGAGGAACTGCACCTTTAGGCCATCTCAGCTTGCTGGGCCTTTTGTTAAACCCTTCT GTCTACTGGCCTCCCTTTGTGTGCATACGCCTCTTGTTCATGTCAGCTTATATGTGACACTGCAGCAGAA AGGCTCTGAAGGTCCAAAGAGTTTCTGCAAAGTGTATGTGACCATCATTTCCCAGGCCATTAGGGTTGCC TCACTGTAGCAGGTTCTAGGCTACCAGAAGAGGGGCAGCTTTTTCATACCAATTCCAACTTTCAGGGGCT GACTCTCCAGGGAGCTGATGTCATCACACTCTCCATGTTAGTAATGGCAGAGCAGTCTAAACAGAGTCCG GGAGAATGCTGGCAAAGGCTGGCTGTGTATACCCACTAGGCTGCCCCACGTGCTCCCGAGAGATGACACT AGTCAGAAAATTGGCAGTGGCAGAGAATCCAAACTCAACAAGTGCTCCTGAAAGAAACGCTAGAAGCCTA AGAACTGTGGTCTGGTGTTCCAGCTGAGGCAGGGGGATTTGGTAGGAAGGAGCCAGTGAACTTGGCTTTC CTGTTTCTATCTTTCATTAAAAAGAATAGAAGGATTCAGTCATAAAGAGGTAAAAAACTGTCACGGTACG AAATCTTAGTGCCCACGGAGGCCTCGAGCAGAGAGAATGAAAGTCTTTTTTTTTTTTTTTTTTTTTTAGC ATGGCAATAAATATTCTAGCATCCCTAACTAAAGGGGACTAGACAGTTAGAGACTCTGTCACCCTAGCTA TACCAGCAGAAAACCTGTTCAGGCAGGCTTTCTGGGTGTGACTGATTCCCAGCCTGTGGCAGGGCGTGGT CCCAACTACTCAGCCTAGCACAGGCTGGCAGTTGGTACTGAATTGTCAGATGTGGAGTATTAGTGACACC ACACATTTAATTCAGCTTTGTCCAAAGGAAAGCTTAAAACCCAATACAGTCTAGTTTCCTGGTTCCGTTT TAGAAAAGGAAAACGTGAACAAACTTAGAAAGGGAAGGAAATCCCATCAGTGAATCCTGAAACTGGTTTT AAGTGCTTTCCTTCTCCTCATGCCCAAGAGATCTGTGCCATAGAACAAGATACCAGGCACTTAAAGCCTT TTCCTGAATTGGAAAGGAAAAGAGGCCCAAGTGCAAAAGAAAAAACATTTTAGAAACGGACAGCTTATAA AAATAAAGGGAAGAAAGGAGGCAGCATGGAGAGAGGCCTGTGCTAGAAGCTCCATGGACGTGTCTGCACA GGGTCCTCAGCTCATCCATGCGGCCTGGGTGTCCTTTTACTCAGCTTTATAACAAATGTGGCTCCAAGCT CAGGTGCCTTTGAGTTCTAGGAGGCTGTGGGTTTTATTCAACTACGGTTGGGAGAATGAGACCTGGAGTC ATGTTGAAGGTGCCCAACCTAAAAATGTAGGCTTTCATGTTGCAAAGAACTCCAGAGTCAGTAGTTAGGT TTGGTTTGGTTTTGGACATGATAAACCTGCCAAGAGTCAACAGGTCACTTGATCATGCTGCAGTGGGTAG TTCTAAGGATGGAAAGGTGACAGTATTACTCTCGAGAGGCAATTCAGTCCTGGGCAAAGGTATTAGTACA ATAAGCGTTAAGGGCAGAGTCTACCTTGAAACCAATTAAGCAGCTTGGTATTCATAAATATTGGGATTGG ATGGCCTCCATCCAGAAATCACTATGGGTGAGCATACCTGTCTCAGCTGTTTGGCCAATGTGCATAACCT ACTCGGATCCCCACCTGACACTAACCAGAGTCAGCACAGGCCCCGAGGAGCCCGAAGTCTGCTGCTGTGC AGCATGGAATTCCTTTAAAAAGGTGCACTACAGTTTTAGCGGGGAGGGGGATAGGAAGACGCAGAGCAAA TGAGCTCCGGAGTCCCTGCAGGTGAATAAACACACAGATCTGCATCTGATAGAACTTTGATGGATTTTCA AAAAGCCGTTGACAAGGCTCTGCTATACAGTCTATAAAAATTGTTATTATGGGATTGGAAGAAACACGTG GTCATGAATAGAAAAAAAACAAACCCAAAGGTAGGAAGGTCAAGGTCATTTCTTAGATGGAGAAGTTGTG AAAGATGTCCTTGGAGATGAGTTTTAGGACCAGCATTACTAAGGCAGGTGGGCAGACAGTGACCTCTCTA GGTGTGTCCACAGAGTTTTTCAGGAGAGAAAACTGCCTGACCTTTGGGACTAAGCTGCGGAATCTTCTTA CTAAGCTTGAAGAGTGGAGAGGCGAGAGGTGAGCTACTTTGTGAGCCAAAGCTTATGTGACATGGTTGGG GAAACAGTCCAAACTGTTCTGAGAAGGTGAACTGTTACGACCCAGGACAATTAGAAAAATTCACCCACCA TGCCGCACATTACTGGGTAAAAGCAGGGCAGCAGGGAACAAAACTCCAGACTCTTGGGCCGTCCCCATTT GCAACAGCACACATAGTTTCTGGTATATTTGTTGGGAAAGATAAAACTCTAGCAGTTGTTGAGGGGAGGA TGTATAAAATGGTCATGGGGATGAAAGGATCTCTGAGACCACAGAGGCTCAGACTCACTGTTAAGAATAG AAAACTGGGTATGCGTTTCATGTAGCCAGCAGAACTGAAGTGTGCTGTGACAAGCCAATGTGAATTTCTA CCAAATAGTAGAGCATACCACTTGAAGAAGGAAAGAACCGAAGAGCAAACAAAAGTTCTGCGTAATGAGA CTCACCTTTTCTCGCTGAAAGCACTAAGAGGTGGGAGGAGGCCTGCACAGGCTGGAGGAGGGTTTGGGCA GAGCGAAGACCCGGCCAGGACCTTGGTGAGATGGGGTGCCGCCCACCTCCTGCGGATACTCTTGGAGAGT TGTTCCCCCAGGGGGCTCTGCCCCACCTGGAGAAGGAAGCTGCCTGGTGTGGAGTGACTCAAATCAGTAT ACCTATCTGCTGCACCTTCACTCTCCAGGGTACATGCTTTAAAACCGACCCGCAACAAGTATTGGAAAAA TGTATCCAGTCTGAAGATGTTTGTGTATCTGTTTACATCCAGAGTTCTGTGACACATGCCCCCCAGATTG CTGCAAAGATCCCAAGGCATTGATTGCACTTGATTAAGCTTTTGTCTGTAGGTGAAAGAACAAGTTTAGG TCGAGGACTGGCCCCTAGGCTGCTGCTGTGACCCTTGTCCCATGTGGCTTGTTTGCCTGTCCGGGACTCT TCGATGTGCCCAGGGGAGCGTGTTCCTGTCTCTTCCATGCCGTCCTGCAGTCCTTATCTGCTCGCCTGAG GGAAGAGTAGCTGTAGCTACAAGGGAAGCCTGCCTGGAAGAGCCGAGCACCTGTGCCCATGGCTTCTGGT CATGAAACGAGTTAATGATGGCAGAGGAGCTTCCTCCCCACTTCGCAGCGCCACATTATCCATCCTCTGA GATAAGTAGGCTGGTTTAACCATTGGAATGGACCTTTCAGTGGAAACCCTGAGAGTCTGAGAACCCCCAG ACCAACCCTTCCCTCCCTTTCCCCACCTCTTACAGTGTTTGGACAGGAGGGTATGGTGCTGCTCTGTGTA GCAAGTACTTTGGCTTATGAAAGAGGCAGCCACGCATTTTGCACTAGGAAGAATCAGTAATCACTTTTCA GAAGACTTCTATGGACCACAAATATATTACGGAGGAACAGATTTTGCTAAGACATAATCTAGTTTTATAA CTCAATCATGAATGAACCATGTGTGGCAAACTTGCAGTTTAAAGGGGTCCCATCAGTGAAAGAAACTGAT TTTTTTTAACGGACTGCTTTTAGTTAAATTGAAGAAAGTCAGCTCTTGTCAAAAGGTCTAAACTTTCCCG CCTCAATCCTAAAAGCATGTCAACAATCCACATCAGATGCCATAAATATGAACTGCAGGATAAAATGGTA CAATCTTAGTGAATGGGAATTGGAATCAAAAGAGTTTGCTGTCCTTCTTAGAATGTTCTAAAATGTCAAG GCAGTTGCTTGTGTTTAACTGTGAACAAATAAAAATTTATTGTTTTGCACTAC Download Select all
Length	54023
OMIM ID	605284
HGNC ID	HGNC:12362
Unigene ID	Hs.370854
Ensembl ID	ENSG00000165699
PharmGKB ID	-

mRNA Information

mRNA ID	NM_001162427.1
Exon	join(738..828,10276..10338,16419..16604,18067..18170, 21879..22023,23398..23552,23935..24008,32914..33089, 33803..33918,34258..34369,34679..34800,38001..38070, 38536..38640,39232..39790,40917..40960,41554..41720, 42584..42766,43672..43782,44534..44656,47761..47948, 48026..48187,48617..54023)
mRNA Sequence	>7248 ACGACGGGGGAGGTGCTGTACGTCCAAGATGGCGGCGCCCTGTAGGCTGGAGGGACTGTGAGGT AAACAGCTGAGGGGGAGGAGACGGTGGTGACCATGAAAGACACCAGGTTGACAGCACTGGAAAC TGAAGTACCAGTTGTCGCTAGAACAGTTTGGTAGTGGCCCCAATGAAGAACCTTCAGAACCTGT AGCACACGTCCTGGAGCCAGCACAGCGCCTTCGAGCGAGAGAATGGCCCAACAAGCAAATGTCG GGGAGCTTCTTGCCATGCTGGACTCCCCCATGCTGGGTGTGCGGGACGACGTGACAGCTGTCTT TAAAGAGAACCTCAATTCTGACCGTGGCCCTATGCTTGTAAACACCTTGGTGGATTATTACCTG GAAACCAGCTCTCAGCCGGCATTGCACATCCTGACCACCTTGCAAGAGCCACATGACAAGATGG ACACTGACGTCGTTGTCCTCACAACAGGCGTCTTGGTGTTGATAACCATGCTACCAATGATTCC ACAGTCTGGGAAACAGCATCTTCTTGATTTCTTTGACATTTTTGGCCGTCTGTCATCATGGTGC CTGAAGAAACCAGGCCACGTGGCGGAAGTCTATCTCGTCCATCTCCATGCCAGTGTGTACGCAC TCTTTCATCGCCTTTATGGAATGTACCCTTGCAACTTCGTCTCCTTTTTGCGTTCTCATTACAG TATGAAAGAAAACCTGGAGACTTTTGAAGAAGTGGTCAAGCCAATGATGGAGCATGTGCGAATT CATCCGGAATTAGTGACTGGATCCAAGGACCATGAACTGGACCCTCGAAGGTGGAAGAGATTAG AAACTCATGATGTTGTGATCGAGTGTGCCAAAATCTCTCTGGATCCCACAGAAGCCTCATATGA AGATGGCTATTCTGTGTCTCACCAAATCTCAGCCCGCTTTCCTCATCGTTCAGCCGATGTCACC ACCAGCCCTTATGCTGACACACAGAATAGCTATGGGTGTGCTACTTCTACCCCTTACTCCACGT CTCGGCTGATGTTGTTAAATATGCCAGGGCAGCTACCTCAGACTCTGAGTTCCCCATCGACACG GCTGATAACTGAACCACCACAAGCTACTCTTTGGAGCCCATCTATGGTTTGTGGTATGACCACT CCTCCAACTTCTCCTGGAAATGTCCCACCTGATCTGTCACACCCTTACAGTAAAGTCTTTGGTA CAACTGCAGGTGGAAAAGGAACTCCTCTGGGAACCCCAGCAACCTCTCCTCCTCCAGCCCCACT CTGTCATTCGGATGACTACGTGCACATTTCACTCCCCCAGGCCACAGTCACACCCCCCAGGAAG GAAGAGAGAATGGATTCTGCAAGACCATGTCTACACAGACAACACCATCTTCTGAATGACAGAG GATCAGAAGAGCCACCTGGCAGCAAAGGTTCTGTCACTCTAAGTGATCTTCCAGGGTTTTTAGG TGATCTGGCCTCTGAAGAAGATAGTATTGAAAAAGATAAAGAAGAAGCTGCAATATCTAGAGAA CTTTCTGAGATCACCACAGCAGAGGCAGAGCCTGTGGTTCCTCGAGGAGGCTTTGACTCTCCCT TTTACCGAGACAGTCTCCCAGGTTCTCAGCGGAAGACCCACTCGGCAGCCTCCAGTTCTCAGGG CGCCAGCGTGAACCCTGAGCCTTTACACTCCTCCCTGGACAAGCTTGGGCCTGACACACCAAAG CAAGCCTTTACTCCCATAGACCTGCCCTGCGGCAGTGCTGATGAAAGCCCTGCGGGAGACAGGG AATGCCAGACTTCTTTGGAGACCAGTATCTTCACTCCCAGTCCTTGTAAAATTCCACCTCCGAC GAGAGTGGGCTTTGGAAGCGGGCAGCCTCCCCCGTATGATCATCTTTTTGAGGTGGCATTGCCA AAGACAGCCCATCATTTTGTCATCAGGAAGACTGAGGAGCTGTTAAAGAAAGCAAAAGGAAACA CAGAGGAAGATGGTGTGCCCTCTACCTCCCCAATGGAAGTGCTGGACAGACTGATACAGCAGGG AGCAGACGCGCACAGCAAGGAGCTGAACAAGTTGCCTTTACCCAGCAAGTCTGTCGACTGGACC CACTTTGGAGGCTCTCCTCCTTCAGATGAGATCCGCACCCTCCGAGACCAGTTGCTTTTACTGC ACAACCAGTTACTCTATGAGCGTTTTAAGAGGCAGCAGCATGCCCTCCGGAACAGGCGGCTCCT CCGCAAGGTGATCAAAGCAGCAGCTCTGGAGGAACATAATGCTGCCATGAAAGATCAGTTGAAG TTACAAGAGAAGGACATCCAGATGTGGAAGGTTAGTCTGCAGAAAGAACAAGCTAGATACAATC AGCTCCAGGAGCAGCGTGACACTATGGTAACCAAGCTCCACAGCCAGATCAGACAGCTGCAGCA TGACCGAGAGGAATTCTACAACCAGAGCCAGGAATTACAGACGAAGCTGGAGGACTGCAGGAAC ATGATTGCGGAGCTGCGGATAGAACTGAAGAAGGCCAACAACAAGGTGTGTCACACTGAGCTGC TGCTCAGTCAGGTTTCCCAAAAGCTCTCAAACAGTGAGTCGGTCCAGCAGCAGATGGAGTTCTT GAACAGGCAGCTGTTGGTTCTTGGGGAGGTCAACGAGCTCTATTTGGAACAACTGCAGAACAAG CACTCAGATACCACAAAGGAAGTAGAAATGATGAAAGCCGCCTATCGGAAAGAGCTAGAAAAAA ACAGAAGCCATGTTCTCCAGCAGACTCAGAGGCTTGATACCTCCCAAAAACGGATTTTGGAACT GGAATCTCACCTGGCCAAGAAAGACCACCTTCTTTTGGAACAGAAGAAATATCTAGAGGATGTC AAACTCCAGGCAAGAGGACAGCTGCAGGCCGCAGAGAGCAGGTATGAGGCTCAGAAAAGGATAA CCCAGGTGTTTGAATTGGAGATCTTAGATTTATATGGCAGGTTGGAGAAAGATGGCCTCCTGAA AAAACTTGAAGAAGAAAAAGCAGAAGCAGCTGAAGCAGCAGAAGAAAGGCTTGACTGTTGTAAT GACGGGTGCTCAGATTCCATGGTAGGGCACAATGAAGAGGCATCTGGCCACAACGGTGAGACCA AGACCCCCAGGCCCAGCAGCGCCCGGGGCAGTAGTGGAAGCAGAGGTGGTGGAGGCAGCAGCAG CAGCAGCAGCGAGCTTTCTACCCCAGAGAAACCCCCACACCAGAGGGCAGGCCCATTCAGCAGT CGGTGGGAGACGACTATGGGAGAAGCGTCTGCCAGCATCCCCACCACTGTGGGCTCACTTCCCA GTTCAAAAAGCTTCCTGGGTATGAAGGCTCGAGAGTTATTTCGTAATAAGAGCGAGAGCCAGTG TGATGAGGACGGCATGACCAGTAGCCTTTCTGAGAGCCTAAAGACAGAACTGGGCAAAGACTTG GGTGTGGAAGCCAAGATTCCCCTGAACCTAGATGGCCCTCACCCGTCTCCCCCGACCCCGGACA GTGTTGGACAGCTACATATCATGGACTACAATGAGACTCATCATGAACACAGCTAAGGAATGAT GGTCAATCAGTGTTAACTTGCATATTGTTGGCACAGAACAGGAGGTGTGAATGCACGTTTCAAA GCTTTCCTGTTTCCAGGGTCTGAGTGCAAGTTCATGTGTGGAAATGGGACGGAGGTCCTTTGGA CAGCTGACTGAATGCAGAACGGTTTTTGGATCTGGCATTGAAATGCCTCTTGACCTTCCCCTCC ACCCGCCCTAACCCCCTCTCATTTACCTCGCAGTGTGTTCTAATCCAAGGGCCAGTTGGTGTTC CTCAGTAGCTTTACTTTCTTCCTTTCCCCCCCAAATGGTTGCGTCCTTTGAACCTGTGCAATAT GAGGCCAAATTTAATCTTTGAGTCTAACACACCACTTTCTGCTTTCCCGAAGTTCAGATAACTG GGTTGGCTCTCAATTAGACCAGGTAGTTTGTTGCATTGCAGGTAAGTCTGGTTTTGTCCCTTCC AGGAGGACATAGCCTGCAAAGCTGGTTGTCTTTACATGAAAGCGTTTACATGAGACTTTCCGAC TGCTTTTTTGATTCTGAAGTTCAGCATCTAAAGCAGCAGGTCTAGAAGAACAACGGTTTATTCA TACTTGCATTCTTTTGGCAGTTCTGATAAGCTTCCTAGAAAGTTCTGTGTAAACAGAAGCCTGT TTCAGAAATCTGGAGCTGGCACTGTGGAGACCACACACCCTTTGGGAAAGCTCTTGTCTCTTCT TCCCCCACTACCTCTTATTTATTTGGTGTTTGCTTGAATGCTGGTACTATTGTGACCACAGGCT GGTGTGTAGGTGGTAAAACCTGTTCTCCATAGGAGGGAAGGAGCAGTCACTGGGAGAGGTTACC CGAGAAGCACTTGAGCATGAGGAACTGCACCTTTAGGCCATCTCAGCTTGCTGGGCCTTTTGTT AAACCCTTCTGTCTACTGGCCTCCCTTTGTGTGCATACGCCTCTTGTTCATGTCAGCTTATATG TGACACTGCAGCAGAAAGGCTCTGAAGGTCCAAAGAGTTTCTGCAAAGTGTATGTGACCATCAT TTCCCAGGCCATTAGGGTTGCCTCACTGTAGCAGGTTCTAGGCTACCAGAAGAGGGGCAGCTTT TTCATACCAATTCCAACTTTCAGGGGCTGACTCTCCAGGGAGCTGATGTCATCACACTCTCCAT GTTAGTAATGGCAGAGCAGTCTAAACAGAGTCCGGGAGAATGCTGGCAAAGGCTGGCTGTGTAT ACCCACTAGGCTGCCCCACGTGCTCCCGAGAGATGACACTAGTCAGAAAATTGGCAGTGGCAGA GAATCCAAACTCAACAAGTGCTCCTGAAAGAAACGCTAGAAGCCTAAGAACTGTGGTCTGGTGT TCCAGCTGAGGCAGGGGGATTTGGTAGGAAGGAGCCAGTGAACTTGGCTTTCCTGTTTCTATCT TTCATTAAAAAGAATAGAAGGATTCAGTCATAAAGAGGTAAAAAACTGTCACGGTACGAAATCT TAGTGCCCACGGAGGCCTCGAGCAGAGAGAATGAAAGTCTTTTTTTTTTTTTTTTTTTTTTAGC ATGGCAATAAATATTCTAGCATCCCTAACTAAAGGGGACTAGACAGTTAGAGACTCTGTCACCC TAGCTATACCAGCAGAAAACCTGTTCAGGCAGGCTTTCTGGGTGTGACTGATTCCCAGCCTGTG GCAGGGCGTGGTCCCAACTACTCAGCCTAGCACAGGCTGGCAGTTGGTACTGAATTGTCAGATG TGGAGTATTAGTGACACCACACATTTAATTCAGCTTTGTCCAAAGGAAAGCTTAAAACCCAATA CAGTCTAGTTTCCTGGTTCCGTTTTAGAAAAGGAAAACGTGAACAAACTTAGAAAGGGAAGGAA ATCCCATCAGTGAATCCTGAAACTGGTTTTAAGTGCTTTCCTTCTCCTCATGCCCAAGAGATCT GTGCCATAGAACAAGATACCAGGCACTTAAAGCCTTTTCCTGAATTGGAAAGGAAAAGAGGCCC AAGTGCAAAAGAAAAAACATTTTAGAAACGGACAGCTTATAAAAATAAAGGGAAGAAAGGAGGC AGCATGGAGAGAGGCCTGTGCTAGAAGCTCCATGGACGTGTCTGCACAGGGTCCTCAGCTCATC CATGCGGCCTGGGTGTCCTTTTACTCAGCTTTATAACAAATGTGGCTCCAAGCTCAGGTGCCTT TGAGTTCTAGGAGGCTGTGGGTTTTATTCAACTACGGTTGGGAGAATGAGACCTGGAGTCATGT TGAAGGTGCCCAACCTAAAAATGTAGGCTTTCATGTTGCAAAGAACTCCAGAGTCAGTAGTTAG GTTTGGTTTGGTTTTGGACATGATAAACCTGCCAAGAGTCAACAGGTCACTTGATCATGCTGCA GTGGGTAGTTCTAAGGATGGAAAGGTGACAGTATTACTCTCGAGAGGCAATTCAGTCCTGGGCA AAGGTATTAGTACAATAAGCGTTAAGGGCAGAGTCTACCTTGAAACCAATTAAGCAGCTTGGTA TTCATAAATATTGGGATTGGATGGCCTCCATCCAGAAATCACTATGGGTGAGCATACCTGTCTC AGCTGTTTGGCCAATGTGCATAACCTACTCGGATCCCCACCTGACACTAACCAGAGTCAGCACA GGCCCCGAGGAGCCCGAAGTCTGCTGCTGTGCAGCATGGAATTCCTTTAAAAAGGTGCACTACA GTTTTAGCGGGGAGGGGGATAGGAAGACGCAGAGCAAATGAGCTCCGGAGTCCCTGCAGGTGAA TAAACACACAGATCTGCATCTGATAGAACTTTGATGGATTTTCAAAAAGCCGTTGACAAGGCTC TGCTATACAGTCTATAAAAATTGTTATTATGGGATTGGAAGAAACACGTGGTCATGAATAGAAA AAAAACAAACCCAAAGGTAGGAAGGTCAAGGTCATTTCTTAGATGGAGAAGTTGTGAAAGATGT CCTTGGAGATGAGTTTTAGGACCAGCATTACTAAGGCAGGTGGGCAGACAGTGACCTCTCTAGG TGTGTCCACAGAGTTTTTCAGGAGAGAAAACTGCCTGACCTTTGGGACTAAGCTGCGGAATCTT CTTACTAAGCTTGAAGAGTGGAGAGGCGAGAGGTGAGCTACTTTGTGAGCCAAAGCTTATGTGA CATGGTTGGGGAAACAGTCCAAACTGTTCTGAGAAGGTGAACTGTTACGACCCAGGACAATTAG AAAAATTCACCCACCATGCCGCACATTACTGGGTAAAAGCAGGGCAGCAGGGAACAAAACTCCA GACTCTTGGGCCGTCCCCATTTGCAACAGCACACATAGTTTCTGGTATATTTGTTGGGAAAGAT AAAACTCTAGCAGTTGTTGAGGGGAGGATGTATAAAATGGTCATGGGGATGAAAGGATCTCTGA GACCACAGAGGCTCAGACTCACTGTTAAGAATAGAAAACTGGGTATGCGTTTCATGTAGCCAGC AGAACTGAAGTGTGCTGTGACAAGCCAATGTGAATTTCTACCAAATAGTAGAGCATACCACTTG AAGAAGGAAAGAACCGAAGAGCAAACAAAAGTTCTGCGTAATGAGACTCACCTTTTCTCGCTGA AAGCACTAAGAGGTGGGAGGAGGCCTGCACAGGCTGGAGGAGGGTTTGGGCAGAGCGAAGACCC GGCCAGGACCTTGGTGAGATGGGGTGCCGCCCACCTCCTGCGGATACTCTTGGAGAGTTGTTCC CCCAGGGGGCTCTGCCCCACCTGGAGAAGGAAGCTGCCTGGTGTGGAGTGACTCAAATCAGTAT ACCTATCTGCTGCACCTTCACTCTCCAGGGTACATGCTTTAAAACCGACCCGCAACAAGTATTG GAAAAATGTATCCAGTCTGAAGATGTTTGTGTATCTGTTTACATCCAGAGTTCTGTGACACATG CCCCCCAGATTGCTGCAAAGATCCCAAGGCATTGATTGCACTTGATTAAGCTTTTGTCTGTAGG TGAAAGAACAAGTTTAGGTCGAGGACTGGCCCCTAGGCTGCTGCTGTGACCCTTGTCCCATGTG GCTTGTTTGCCTGTCCGGGACTCTTCGATGTGCCCAGGGGAGCGTGTTCCTGTCTCTTCCATGC CGTCCTGCAGTCCTTATCTGCTCGCCTGAGGGAAGAGTAGCTGTAGCTACAAGGGAAGCCTGCC TGGAAGAGCCGAGCACCTGTGCCCATGGCTTCTGGTCATGAAACGAGTTAATGATGGCAGAGGA GCTTCCTCCCCACTTCGCAGCGCCACATTATCCATCCTCTGAGATAAGTAGGCTGGTTTAACCA TTGGAATGGACCTTTCAGTGGAAACCCTGAGAGTCTGAGAACCCCCAGACCAACCCTTCCCTCC CTTTCCCCACCTCTTACAGTGTTTGGACAGGAGGGTATGGTGCTGCTCTGTGTAGCAAGTACTT TGGCTTATGAAAGAGGCAGCCACGCATTTTGCACTAGGAAGAATCAGTAATCACTTTTCAGAAG ACTTCTATGGACCACAAATATATTACGGAGGAACAGATTTTGCTAAGACATAATCTAGTTTTAT AACTCAATCATGAATGAACCATGTGTGGCAAACTTGCAGTTTAAAGGGGTCCCATCAGTGAAAG AAACTGATTTTTTTTAACGGACTGCTTTTAGTTAAATTGAAGAAAGTCAGCTCTTGTCAAAAGG TCTAAACTTTCCCGCCTCAATCCTAAAAGCATGTCAACAATCCACATCAGATGCCATAAATATG AACTGCAGGATAAAATGGTACAATCTTAGTGAATGGGAATTGGAATCAAAAGAGTTTGCTGTCC TTCTTAGAATGTTCTAAAATGTCAAGGCAGTTGCTTGTGTTTAACTGTGAACAAATAAAAATTT ATTGTTTTGCACTACAAAAAAAAAA Download Select all
Length	8473

CDS Information

Location	join(16499..16604,18067..18170,21879..22023,23398..23552, 23935..24008,32914..33089,33803..33918,34258..34369, 34679..34800,38001..38070,38536..38640,39232..39790, 40917..40960,41554..41720,42584..42766,43672..43782, 44534..44656,47761..47948,48026..48187,48617..49136)
CDS Sequence	>lcl\|NM_001162427.1_cds_NP_001155899.1_1 [gene=TSC1] [protein=hamartin isoform 4] [protein_id=NP_001155899.1] [location=235..3576] ATGGCCCAACAAGCAAATGTCGGGGAGCTTCTTGCCATGCTGGACTCCCCCATGCTGGGTGTGCGGGACG ACGTGACAGCTGTCTTTAAAGAGAACCTCAATTCTGACCGTGGCCCTATGCTTGTAAACACCTTGGTGGA TTATTACCTGGAAACCAGCTCTCAGCCGGCATTGCACATCCTGACCACCTTGCAAGAGCCACATGACAAG ATGGACACTGACGTCGTTGTCCTCACAACAGGCGTCTTGGTGTTGATAACCATGCTACCAATGATTCCAC AGTCTGGGAAACAGCATCTTCTTGATTTCTTTGACATTTTTGGCCGTCTGTCATCATGGTGCCTGAAGAA ACCAGGCCACGTGGCGGAAGTCTATCTCGTCCATCTCCATGCCAGTGTGTACGCACTCTTTCATCGCCTT TATGGAATGTACCCTTGCAACTTCGTCTCCTTTTTGCGTTCTCATTACAGTATGAAAGAAAACCTGGAGA CTTTTGAAGAAGTGGTCAAGCCAATGATGGAGCATGTGCGAATTCATCCGGAATTAGTGACTGGATCCAA GGACCATGAACTGGACCCTCGAAGGTGGAAGAGATTAGAAACTCATGATGTTGTGATCGAGTGTGCCAAA ATCTCTCTGGATCCCACAGAAGCCTCATATGAAGATGGCTATTCTGTGTCTCACCAAATCTCAGCCCGCT TTCCTCATCGTTCAGCCGATGTCACCACCAGCCCTTATGCTGACACACAGAATAGCTATGGGTGTGCTAC TTCTACCCCTTACTCCACGTCTCGGCTGATGTTGTTAAATATGCCAGGGCAGCTACCTCAGACTCTGAGT TCCCCATCGACACGGCTGATAACTGAACCACCACAAGCTACTCTTTGGAGCCCATCTATGGTTTGTGGTA TGACCACTCCTCCAACTTCTCCTGGAAATGTCCCACCTGATCTGTCACACCCTTACAGTAAAGTCTTTGG TACAACTGCAGGTGGAAAAGGAACTCCTCTGGGAACCCCAGCAACCTCTCCTCCTCCAGCCCCACTCTGT CATTCGGATGACTACGTGCACATTTCACTCCCCCAGGCCACAGTCACACCCCCCAGGAAGGAAGAGAGAA TGGATTCTGCAAGACCATGTCTACACAGACAACACCATCTTCTGAATGACAGAGGATCAGAAGAGCCACC TGGCAGCAAAGGTTCTGTCACTCTAAGTGATCTTCCAGGGTTTTTAGGTGATCTGGCCTCTGAAGAAGAT AGTATTGAAAAAGATAAAGAAGAAGCTGCAATATCTAGAGAACTTTCTGAGATCACCACAGCAGAGGCAG AGCCTGTGGTTCCTCGAGGAGGCTTTGACTCTCCCTTTTACCGAGACAGTCTCCCAGGTTCTCAGCGGAA GACCCACTCGGCAGCCTCCAGTTCTCAGGGCGCCAGCGTGAACCCTGAGCCTTTACACTCCTCCCTGGAC AAGCTTGGGCCTGACACACCAAAGCAAGCCTTTACTCCCATAGACCTGCCCTGCGGCAGTGCTGATGAAA GCCCTGCGGGAGACAGGGAATGCCAGACTTCTTTGGAGACCAGTATCTTCACTCCCAGTCCTTGTAAAAT TCCACCTCCGACGAGAGTGGGCTTTGGAAGCGGGCAGCCTCCCCCGTATGATCATCTTTTTGAGGTGGCA TTGCCAAAGACAGCCCATCATTTTGTCATCAGGAAGACTGAGGAGCTGTTAAAGAAAGCAAAAGGAAACA CAGAGGAAGATGGTGTGCCCTCTACCTCCCCAATGGAAGTGCTGGACAGACTGATACAGCAGGGAGCAGA CGCGCACAGCAAGGAGCTGAACAAGTTGCCTTTACCCAGCAAGTCTGTCGACTGGACCCACTTTGGAGGC TCTCCTCCTTCAGATGAGATCCGCACCCTCCGAGACCAGTTGCTTTTACTGCACAACCAGTTACTCTATG AGCGTTTTAAGAGGCAGCAGCATGCCCTCCGGAACAGGCGGCTCCTCCGCAAGGTGATCAAAGCAGCAGC TCTGGAGGAACATAATGCTGCCATGAAAGATCAGTTGAAGTTACAAGAGAAGGACATCCAGATGTGGAAG GTTAGTCTGCAGAAAGAACAAGCTAGATACAATCAGCTCCAGGAGCAGCGTGACACTATGGTAACCAAGC TCCACAGCCAGATCAGACAGCTGCAGCATGACCGAGAGGAATTCTACAACCAGAGCCAGGAATTACAGAC GAAGCTGGAGGACTGCAGGAACATGATTGCGGAGCTGCGGATAGAACTGAAGAAGGCCAACAACAAGGTG TGTCACACTGAGCTGCTGCTCAGTCAGGTTTCCCAAAAGCTCTCAAACAGTGAGTCGGTCCAGCAGCAGA TGGAGTTCTTGAACAGGCAGCTGTTGGTTCTTGGGGAGGTCAACGAGCTCTATTTGGAACAACTGCAGAA CAAGCACTCAGATACCACAAAGGAAGTAGAAATGATGAAAGCCGCCTATCGGAAAGAGCTAGAAAAAAAC AGAAGCCATGTTCTCCAGCAGACTCAGAGGCTTGATACCTCCCAAAAACGGATTTTGGAACTGGAATCTC ACCTGGCCAAGAAAGACCACCTTCTTTTGGAACAGAAGAAATATCTAGAGGATGTCAAACTCCAGGCAAG AGGACAGCTGCAGGCCGCAGAGAGCAGGTATGAGGCTCAGAAAAGGATAACCCAGGTGTTTGAATTGGAG ATCTTAGATTTATATGGCAGGTTGGAGAAAGATGGCCTCCTGAAAAAACTTGAAGAAGAAAAAGCAGAAG CAGCTGAAGCAGCAGAAGAAAGGCTTGACTGTTGTAATGACGGGTGCTCAGATTCCATGGTAGGGCACAA TGAAGAGGCATCTGGCCACAACGGTGAGACCAAGACCCCCAGGCCCAGCAGCGCCCGGGGCAGTAGTGGA AGCAGAGGTGGTGGAGGCAGCAGCAGCAGCAGCAGCGAGCTTTCTACCCCAGAGAAACCCCCACACCAGA GGGCAGGCCCATTCAGCAGTCGGTGGGAGACGACTATGGGAGAAGCGTCTGCCAGCATCCCCACCACTGT GGGCTCACTTCCCAGTTCAAAAAGCTTCCTGGGTATGAAGGCTCGAGAGTTATTTCGTAATAAGAGCGAG AGCCAGTGTGATGAGGACGGCATGACCAGTAGCCTTTCTGAGAGCCTAAAGACAGAACTGGGCAAAGACT TGGGTGTGGAAGCCAAGATTCCCCTGAACCTAGATGGCCCTCACCCGTCTCCCCCGACCCCGGACAGTGT TGGACAGCTACATATCATGGACTACAATGAGACTCATCATGAACACAGCTAA Download Select all
CCDS ID	CCDS55350.1

Protein Information

Protein ID	NP_000359.1
Protein Name	Tuberous sclerosis 1
Molecular Wt. (Da)	129636
Protein Sequence	>7248 MAQQANVGELLAMLDSPMLGVRDDVTAVFKENLNSDRGPMLVNTLVDYYLETSSQPALHILTTL QEPHDKHLLDRINEYVGKAATRLSILSLLGHVIRLQPSWKHKLSQAPLLPSLLKCLKMDTDVVV LTTGVLVLITMLPMIPQSGKQHLLDFFDIFGRLSSWCLKKPGHVAEVYLVHLHASVYALFHRLY GMYPCNFVSFLRSHYSMKENLETFEEVVKPMMEHVRIHPELVTGSKDHELDPRRWKRLETHDVV IECAKISLDPTEASYEDGYSVSHQISARFPHRSADVTTSPYADTQNSYGCATSTPYSTSRLMLL NMPGQLPQTLSSPSTRLITEPPQATLWSPSMVCGMTTPPTSPGNVPPDLSHPYSKVFGTTAGGK GTPLGTPATSPPPAPLCHSDDYVHISLPQATVTPPRKEERMDSARPCLHRQHHLLNDRGSEEPP GSKGSVTLSDLPGFLGDLASEEDSIEKDKEEAAISRELSEITTAEAEPVVPRGGFDSPFYRDSL PGSQRKTHSAASSSQGASVNPEPLHSSLDKLGPDTPKQAFTPIDLPCGSADESPAGDRECQTSL ETSIFTPSPCKIPPPTRVGFGSGQPPPYDHLFEVALPKTAHHFVIRKTEELLKKAKGNTEEDGV PSTSPMEVLDRLIQQGADAHSKELNKLPLPSKSVDWTHFGGSPPSDEIRTLRDQLLLLHNQLLY ERFKRQQHALRNRRLLRKVIKAAALEEHNAAMKDQLKLQEKDIQMWKVSLQKEQARYNQLQEQR DTMVTKLHSQIRQLQHDREEFYNQSQELQTKLEDCRNMIAELRIELKKANNKVCHTELLLSQVS QKLSNSESVQQQMEFLNRQLLVLGEVNELYLEQLQNKHSDTTKEVEMMKAAYRKELEKNRSHVL QQTQRLDTSQKRILELESHLAKKDHLLLEQKKYLEDVKLQARGQLQAAESRYEAQKRITQVFEL EILDLYGRLEKDGLLKKLEEEKAEAAEAAEERLDCCNDGCSDSMVGHNEEASGHNGETKTPRPS SARGSSGSRGGGGSSSSSSELSTPEKPPHQRAGPFSSRWETTMGEASASIPTTVGSLPSSKSFL GMKARELFRNKSESQCDEDGMTSSLSESLKTELGKDLGVEAKIPLNLDGPHPSPPTPDSVGQLH IMDYNETHHEHS Download Select all
Length	1164
Uniprot ID	P14416
Ensembl Protein ID	ENSP00000278597

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
T	Phosphorylation	1047
T	Phosphorylation	417
S	Phosphorylation	584
S	Phosphorylation	505
S	Phosphorylation	505;-
S	Phosphorylation	1102;-
S	Phosphorylation	511
S	Phosphorylation	598

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
207	AKT1	1261	NP_005154.2	in vivo	12167664
891	CCNB1	454	NP_114172.1	in vivo	11444800
4478	MSN	2399	NP_002435.1	in vivo;yeast 2-hybrid	12226091
4747	NEFL	1206	NP_006149.2	in vivo	12226091
7249	TSC2	1850	NP_000539.2	in vitro;in vivo;yeast 2-hybrid	10 915 759 164 243 800 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000 000
7430	EZR	475	NP_003370.2	in vitro;in vivo	10806479
7529	YWHAB	3184	NP_003395.1	in vitro	12176984
7531	YWHAE	5457	NP_006752.1	in vitro	12176984
7533	YWHAH	215	NP_003396.1	in vitro	12176984
7534	YWHAZ	3183	NP_003397.1	in vitro	12176984
10971	YWHAQ	886	NP_006817.1	in vitro	12176984

Pathway Information

Pathway Name	Pathway ID
AMPK signaling pathway	hsa04152
Choline metabolism in cancer	hsa05231
Insulin signaling pathway	hsa04910
Longevity regulating pathway - mammal	hsa04211
mTOR signaling pathway	hsa04150
Phospholipase D signaling pathway	hsa04072
PI3K-Akt signaling pathway	hsa04151

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
pfam12718	758-918	Tropomyosin_1
cl22857	758-918	Tropomyosin_1 superfamily
pfam03357	779-881	Snf7
cl21588	779-881	Snf7 superfamily
smart00935	726-821	OmpH
cl21485	726-821	OmpH superfamily
pfam10473	836-953	CENP-F_leu_zip
cl22858	836-953	CENP-F_leu_zip superfamily
cd07596	754-916	BAR_SNX
cl12013	754-916	BAR superfamily
pfam02388	846-918	FemAB
cl17182	846-918	NAT_SF superfamily
pfam04388	2-719	Hamartin
pfam14988	766-932	DUF4515
COG1196	751-971	Smc
COG1196	705-971	Smc
COG0419	705-971	SbcC
TIGR02168	737-970	SMC_prok_B
COG1196	705-971	Smc
TIGR04523	715-953	Mplasa_alph_rch
COG0419	705-963	SbcC
COG4942	717-953	EnvC
TIGR02169	705-971	SMC_prok_A
COG0419	766-971	SbcC
COG1196	687-912	Smc
COG3883	752-953	CwlO1
TIGR02169	705-967	SMC_prok_A
TIGR02168	763-960	SMC_prok_B
TIGR02169	725-961	SMC_prok_A
TIGR02169	717-961	SMC_prok_A
TIGR02168	685-961	SMC_prok_B
pfam05483	710-969	SCP-1
PRK02224	725-973	PRK02224
PRK02224	725-970	PRK02224
TIGR00618	708-962	sbcc
COG0419	706-973	SbcC
TIGR02169	710-971	SMC_prok_A
pfam12128	705-950	DUF3584
COG1196	705-912	Smc
TIGR02168	685-890	SMC_prok_B
pfam13851	710-815	GAS
PRK03918	718-971	PRK03918
COG4372	705-942	COG4372
pfam02463	621-965	SMC_N
pfam13868	718-953	Trichoplein
PRK11637	734-953	PRK11637
TIGR03185	705-937	DNA_S_dndD
pfam08317	729-844	Spc7
pfam01576	736-973	Myosin_tail_1
TIGR04523	737-956	Mplasa_alph_rch
TIGR00618	730-934	sbcc
TIGR00606	706-965	rad50
TIGR02168	705-867	SMC_prok_B
COG1196	779-952	Smc
PRK04778	721-971	PRK04778
pfam13868	705-931	Trichoplein
pfam14643	704-950	DUF4455
COG0419	704-980	SbcC
pfam06160	721-971	EzrA
pfam12795	708-903	MscS_porin
pfam05557	725-938	MAD
pfam00261	779-965	Tropomyosin
pfam04012	795-972	PspA_IM30
COG4372	799-951	COG4372
TIGR04523	716-936	Mplasa_alph_rch
pfam04111	736-852	APG6
pfam05557	687-938	MAD
pfam12128	722-936	DUF3584
COG1579	774-919	COG1579
pfam04156	743-852	IncA
pfam05483	707-972	SCP-1
pfam07926	727-870	TPR_MLP1_2
pfam01576	752-961	Myosin_tail_1
pfam05622	729-945	HOOK
pfam05557	720-971	MAD
PRK05563	768-906	PRK05563
COG2268	717-959	YqiK
pfam04111	754-902	APG6
PRK04863	759-958	mukB
pfam10174	750-942	Cast
COG0497	760-951	RecN
TIGR00606	736-962	rad50
pfam10174	705-928	Cast
COG4717	713-961	YhaN
TIGR02168	804-971	SMC_prok_B
pfam04912	794-914	Dynamitin
pfam14915	729-934	CCDC144C
pfam04156	776-909	IncA
pfam00769	705-916	ERM
PTZ00121	757-961	PTZ00121
pfam04156	762-869	IncA
pfam15558	704-956	DUF4659
pfam06160	731-912	EzrA
TIGR02169	716-908	SMC_prok_A

Ontology Information

HPRD ID	516
Molecular Class	Cytoskeletal associated protein
Molecular Function	Cell adhesion molecule activity (GO:0005194)
Biological Process	Cell growth and/or maintenance (GO:0008151)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO