CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
20057968	2009	Cell line : - Source : - Sample Type : CRC tumor and adjacent normal tissue No. of Sample : 30 GC with high MSI (MSI-H), 15 GC with low MSI (MSI-L), 35 CRC with MSI-H, and 15 CRC with MSI-L smple Stage : -	SSCP and DNA sequencing	Frameshift Mutation	-	Frameshift mutations of TTK might alter cell cycle control in the affected cells and contribute to pathogenesis of cancers with MSI-H.
21163887	2011	Cell line : - Source : - Sample Type : CRC tumor and adjacent normal tissue No. of Sample : 30 Stage : -	Expression profiling and Sequencing	Mutation	-	Heterozygous TTK mutations occur at a high frequency in MSI CRCs.

Gene Details

NC_000006.11 (80714322..80752244)
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Gene Type	protein coding
Gene Family	-
Description	This gene encodes a dual specificity protein kinase with the ability to phosphorylate tyrosine, serine and threonine. Associated with cell proliferation, this protein is essential for chromosome alignment at the centromere during mitosis and is required for centrosome duplication. It has been found to be a critical mitotic checkpoint protein for accurate segregation of chromosomes during mitosis. Tumorigenesis may occur when this protein fails to degrade and produces excess centrosomes resulting in aberrant mitotic spindles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Chromosome	6
Location	6q14.1
Start	80714322
End	80752244
Strand	+
Gene Sequence	Download Select all
Length	37923
OMIM ID	604092
HGNC ID	HGNC:12401
Unigene ID	Hs.169840
Ensembl ID	ENSG00000112742
PharmGKB ID	PA37066

mRNA Information

mRNA ID	?NM_001166691.1
Exon	join(1..109,1226..1378,3205..3427,3782..3888,6210..6353, 6830..6944,7125..7197,7282..7376,8675..8762,9859..9982, 17720..17868,21777..21910,23281..23407,26863..26955, 30381..30538,30662..30813,31871..31995,33363..33443, 35092..35268,35592..35676,36002..36099,37515..37923)
mRNA Sequence	Download Select all
Length	3019

CDS Information

Location	124..2694
CDS Sequence	Download Select all
CCDS ID	CCDS4993.1

Protein Information

Protein ID	NP_001160163.1
Protein Name	TTK protein kinase
Molecular Wt. (Da)	2994696
Protein Sequence	Download Select all
Length	857
Uniprot ID	Q8IZP0
Ensembl Protein ID	ENSP00000279599

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	281;-
T	Phosphorylation	33
S	Phosphorylation	321
S	Phosphorylation	393
S	Phosphorylation	455
S	Phosphorylation	821
S	Phosphorylation	824
S	Phosphorylation	436
S	Phosphorylation	317
S	Phosphorylation	433
S	Phosphorylation	49
S	Phosphorylation	7
S	Phosphorylation	80
Y	Phosphorylation	833
S	Phosphorylation	37
S	Phosphorylation	345
T	Phosphorylation	351
S	Phosphorylation	353

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
566	AZU1	1221	NP_001691.1	in vivo	15304323
203068	TUBB	1852	NP_001060.1	in vivo	15304323

Pathway Information

Pathway Name	Pathway ID
Cell cycle	hsa04110

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd14131	523-791	PKc_Mps1
cl21453	523-791	PKc_like superfamily
cd05122	524-791	PKc_STE
cd06606	529-791	STKc_MAPKKK
cd14014	525-787	STKc_PknB_like
cd00180	531-789	PKc
cd14003	525-790	STKc_AMPK-like
cd14008	531-791	STKc_LKB1_CaMKK
cd05117	525-789	STKc_CAMK
cd14007	527-792	STKc_Aurora
cd08215	525-791	STKc_Nek
cd07829	525-790	STKc_CDK_like
cd06627	525-791	STKc_Cdc7_like
cd05123	531-790	STKc_AGC
cd14009	531-790	STKc_ATG1_ULK_like
cd08217	525-791	STKc_Nek2
cd14002	525-791	STKc_STK36
cd05573	525-790	STKc_ROCK_NDR_like
cd13994	531-791	STKc_HAL4_like
cd14005	525-791	STKc_PIM
cd14099	523-790	STKc_PLK
cd06626	529-791	STKc_MEKK4
cd05579	531-790	STKc_MAST_like
cd05118	525-790	STKc_CMGC
cd05581	525-797	STKc_PDK1
cd14004	525-791	STKc_PASK
cd06623	527-792	PKc_MAPKK_plant_like
cd14121	531-790	STKc_ULK3
cd14137	525-790	STKc_GSK3
cd14119	531-791	STKc_LKB1
cd08530	525-791	STKc_CNK2-like
cd14098	525-790	STKc_Rad53_Cds1
cd14093	531-790	STKc_PhKG
cd13993	525-786	STKc_Pat1_like
cd14118	565-791	STKc_CAMKK
cd08529	525-789	STKc_FA2-like
cd13999	531-786	STKc_MAP3K-like
cd14120	531-790	STKc_ULK1_2-like
cd14069	525-791	STKc_Chk1
cd06632	531-791	STKc_MEKK1_plant
cd14081	525-791	STKc_BRSK1_2
cd13997	528-789	PKc_Wee1_like
cd07840	525-790	STKc_CDK9_like
cd06609	524-797	STKc_MST3_like
cd05572	531-793	STKc_cGK
cd14080	525-791	STKc_TSSK-like
cd14663	525-790	STKc_SnRK3
cd14199	571-792	STKc_CaMKK2
cd14006	531-790	STKc_MLCK-like
cd07838	525-791	STKc_CDK4_6_like
cd07841	525-790	STKc_CDK7
cd05578	525-790	STKc_Yank1
cd14092	547-798	STKc_MSK_C
cd13990	525-790	STKc_TLK
cd07833	525-790	STKc_CDKL
cd07832	525-790	STKc_CCRK
cd14010	525-790	STKc_ULK4
cd13985	525-786	STKc_GAK_like
cd08224	525-786	STKc_Nek6_7
cd08222	525-791	STKc_Nek11
cd14200	565-791	STKc_CaMKK1
cd14091	525-801	STKc_RSK_C
cd07852	523-792	STKc_MAPK15-like
cd06605	528-792	PKc_MAPKK
cd06625	529-791	STKc_MEKK3_like
cd06614	524-792	STKc_PAK
cd14162	525-791	STKc_TSSK4-like
cd07834	525-793	STKc_MAPK
cd14075	525-788	STKc_NIM1
cd05601	531-790	STKc_CRIK
cd14074	577-791	STKc_SNRK
cd14084	525-791	STKc_Chk2
cd14097	523-791	STKc_STK33
cd14202	531-792	STKc_ULK1
cd07835	525-790	STKc_CDK1_CdkB_like
cd07831	525-790	STKc_MOK
cd14165	523-790	STKc_TSSK1_2-like
cd14078	525-791	STKc_MELK
cd08528	525-787	STKc_Nek10
cd14133	525-791	PKc_DYRK_like
cd14103	531-790	STKc_MLCK
cd05600	525-797	STKc_Sid2p_like
cd14186	525-791	STKc_PLK4
cd06612	524-791	STKc_MST1_2
cd14079	525-790	STKc_AMPK_alpha
cd06631	531-791	STKc_YSK4
cd13996	527-786	STKc_EIF2AK
cd07836	525-790	STKc_Pho85
cd07830	525-790	STKc_MAK_like
cd14096	525-791	STKc_RCK1-like
cd05624	525-792	STKc_MRCK_beta
cd06620	527-799	PKc_Byr1_like
cd00192	529-786	PTKc
cd14181	531-790	STKc_PhKG2
cd08228	525-782	STKc_Nek6
cd06608	524-791	STKc_myosinIII_N_like
cd14166	523-791	STKc_CaMKI_gamma
cd14073	525-791	STKc_NUAK
cd05596	525-792	STKc_ROCK
cd06917	524-786	STKc_NAK1_like
cd06613	524-791	STKc_MAP4K3_like
cd13986	525-788	STKc_16
cd07839	525-790	STKc_CDK5
cd14201	525-792	STKc_ULK2
cd05597	525-790	STKc_DMPK_like
cd14046	528-788	STKc_EIF2AK4_GCN2_rpt2
cd06621	528-803	PKc_Pek1_like
cd07857	525-793	STKc_MPK1
cd14089	525-790	STKc_MAPKAPK
cd14189	523-790	STKc_PLK3
cd08218	525-791	STKc_Nek1
cd07861	525-790	STKc_CDK1_euk
cd14182	531-792	STKc_PhKG1
cd05611	528-790	STKc_Rim15_like
cd14066	531-788	STKc_IRAK
cd06644	522-792	STKc_STK10
cd13979	531-786	STKc_Mos
cd06610	525-790	STKc_OSR1_SPAK
cd14191	524-791	STKc_MLCK1
cd06611	524-795	STKc_SLK_like
cd14196	524-791	STKc_DAPK2
cd14077	525-791	STKc_Kin1_2
cd14210	525-791	PKc_DYRK
cd14116	525-791	STKc_Aurora-A
cd06617	618-792	PKc_MKK3_6
cd14086	525-791	STKc_CaMKII
cd07860	528-790	STKc_CDK2_3
cd14040	525-791	STKc_TLK1
cd14164	525-738	STKc_TSSK6-like
cd13982	577-790	STKc_IRE1
cd14095	525-790	STKc_DCKL
cd08219	525-787	STKc_Nek3
cd14041	525-791	STKc_TLK2
cd08225	525-791	STKc_Nek5
cd14107	524-790	STKc_obscurin_rpt1
cd14179	529-792	STKc_MSK1_C
cd05621	518-792	STKc_ROCK2
cd14163	525-791	STKc_TSSK3-like
cd06628	520-791	STKc_Byr2_like
cd06630	529-789	STKc_MEKK1
cd08221	553-789	STKc_Nek9
cd14094	524-810	STKc_CASK
cd05622	518-792	STKc_ROCK1
cd06622	527-810	PKc_PBS2_like
cd06643	525-795	STKc_SLK
cd14188	523-790	STKc_PLK2
cd06641	524-791	STKc_MST3
cd06642	523-791	STKc_STK25
cd14175	525-821	STKc_RSK1_C
cd05570	529-797	STKc_PKC
cd14178	525-791	STKc_RSK3_C
cd14102	524-791	STKc_PIM3
cd14167	524-791	STKc_CaMKI_alpha
cd14187	520-786	STKc_PLK1
cd14180	548-792	STKc_MSK2_C
cd06624	543-791	STKc_ASK
cd05580	527-779	STKc_PKA_like
cd14052	531-789	PTKc_Wee1_fungi
cd07851	524-797	STKc_p38
cd05599	528-792	STKc_NDR_like
cd14106	544-791	STKc_DRAK
cd08223	525-791	STKc_Nek4
cd14194	525-791	STKc_DAPK1
cd14101	531-792	STKc_PIM2
cd06647	523-792	STKc_PAK_I
cd14100	524-791	STKc_PIM1
cd14161	525-791	STKc_NUAK2
cd14083	524-790	STKc_CaMKI
cd06618	527-802	PKc_MKK7
cd14050	524-789	PKc_Myt1
cd06640	524-791	STKc_MST4
cd07837	525-790	STKc_CdkB_plant
cd07843	517-790	STKc_CDC2L1
cd14019	524-790	STKc_Cdc7
cd14105	525-791	STKc_DAPK
cd14070	525-791	STKc_HUNK
cd14117	525-798	STKc_Aurora-B_like
cd14195	525-793	STKc_DAPK3
cd06629	520-791	STKc_Bck1_like
cd06656	525-793	STKc_PAK3
cd06655	525-793	STKc_PAK2
cd07870	525-790	STKc_PFTAIRE2
cd14037	527-786	STKc_NAK_like
cd14108	525-734	STKc_SPEG_rpt1
cd07879	523-790	STKc_p38delta
cd14017	525-788	STKc_TTBK
cd14132	525-790	STKc_CK2_alpha
cd14048	525-788	STKc_EIF2AK3_PERK
cd06607	523-792	STKc_TAO
cd07880	520-790	STKc_p38gamma
cd14087	525-791	STKc_PSKH1
cd07862	525-790	STKc_CDK6
cd14114	525-791	STKc_Twitchin_like
cd07850	525-793	STKc_JNK
cd14176	525-791	STKc_RSK2_C
cd05577	531-790	STKc_GRK
cd05630	523-789	STKc_GRK6
cd07865	525-790	STKc_CDK9
cd14076	525-791	STKc_Kin4
cd07878	598-796	STKc_p38beta
cd14134	525-790	PKc_CLK
cd06654	525-793	STKc_PAK1
cd07845	516-798	STKc_CDK10
cd05609	525-792	STKc_MAST
cd14059	531-788	STKc_MAP3K12_13
cd06633	523-792	STKc_TAO3
cd05631	523-798	STKc_GRK4
cd05623	525-790	STKc_MRCK_alpha
cd06638	525-791	STKc_myosinIIIA_N
cd14168	523-810	STKc_CaMKI_delta
cd07871	521-790	STKc_PCTAIRE3
cd14072	525-734	STKc_MARK
cd14111	581-791	STKc_SPEG_rpt2
cd05612	525-780	STKc_PRKX_like
cd05613	525-792	STKc_MSK1_N
cd06616	641-793	PKc_MKK4
cd14085	525-791	STKc_CaMKIV
cd06648	529-791	STKc_PAK_II
cd07873	525-792	STKc_PCTAIRE1
cd13995	532-788	STKc_MAP3K8
cd14177	522-804	STKc_RSK4_C
cd07848	525-789	STKc_CDKL5
cd07854	525-800	STKc_MAPK4_6
cd14197	570-791	STKc_DRAK1
cd13976	573-790	PK_TRB
cd14104	525-811	STKc_Titin
cd07844	525-790	STKc_PCTAIRE_like
cd14169	524-791	STKc_CaMKI_beta
cd14090	531-791	STKc_Mnk
cd14020	524-793	STKc_KIS
cd05574	528-780	STKc_phototropin_like
cd08229	525-782	STKc_Nek7
cd07869	521-790	STKc_PFTAIRE1
cd08220	547-791	STKc_Nek8
cd14071	525-790	STKc_SIK
cd14185	525-790	STKc_DCKL3
cd07863	525-790	STKc_CDK4
cd14173	524-791	STKc_Mnk2
cd14012	547-790	PK_eIF2AK_GCN2_rpt1
cd13983	530-790	STKc_WNK
cd05583	531-792	STKc_MSK_N
cd07847	525-790	STKc_CDKL1_4
cd05590	531-790	STKc_nPKC_eta
cd14036	527-786	STKc_GAK
cd05592	529-797	STKc_nPKC_theta_like
cd05632	523-797	STKc_GRK5
cd14016	525-740	STKc_CK1
cd05617	525-780	STKc_aPKC_zeta
cd14174	531-792	STKc_Mnk1
cd05582	529-790	STKc_RSK_N
cd05072	527-779	PTKc_Lyn
cd14058	546-796	STKc_TAK1
cd05614	525-792	STKc_MSK2_N
cd07866	525-790	STKc_BUR1
cd14665	525-790	STKc_SnRK2-3
cd06637	524-794	STKc_TNIK
cd05598	525-797	STKc_LATS
cd14061	531-786	STKc_MLK
cd06615	528-803	PKc_MEK
cd05584	528-790	STKc_p70S6K
cd06636	524-791	STKc_MAP4K4_6_N
cd06635	523-792	STKc_TAO1
cd14662	525-790	STKc_SnRK2
cd05618	525-797	STKc_aPKC_iota
cd13978	531-789	STKc_RIP
cd06639	525-792	STKc_myosinIIIB_N
cd07856	567-791	STKc_Sty1_Hog1
cd07846	525-790	STKc_CDKL2_3
cd14193	566-791	STKc_MLCK4
cd14192	566-791	STKc_MLCK3
cd06659	530-791	STKc_PAK6
cd05092	527-785	PTKc_TrkA
cd07855	638-792	STKc_ERK5
cd07876	525-815	STKc_JNK2
cd14209	525-779	STKc_PKA
cd07842	524-790	STKc_CDK8_like
cd07864	525-791	STKc_CDK12
cd06658	535-797	STKc_PAK5
cd14047	525-788	STKc_EIF2AK2_PKR
cd05605	636-797	STKc_GRK4_like
cd07877	598-790	STKc_p38alpha
cd14082	551-790	STKc_PKD
cd05610	525-790	STKc_MASTL
cd07849	525-792	STKc_ERK1_2_like
cd05032	527-787	PTKc_InsR_like
cd05604	528-797	STKc_SGK3
cd07872	521-792	STKc_PCTAIRE2
cd05094	520-785	PTKc_TrkC
cd05588	529-797	STKc_aPKC
cd05049	520-785	PTKc_Trk
cd13987	531-788	STKc_SBK1
cd05607	531-780	STKc_GRK7
cd14198	529-791	STKc_DRAK2
cd14170	525-810	STKc_MAPKAPK2
cd05595	589-780	STKc_PKB_beta
cd06634	523-792	STKc_TAO2
cd05606	638-790	STKc_beta_ARK
cd07859	525-801	STKc_TDY_MAPK
cd06619	643-791	PKc_MKK5
cd05586	531-790	STKc_Sck1_like
cd07853	596-792	STKc_NLK
cd14145	531-786	STKc_MLK1
cd05585	531-790	STKc_YPK1_like
cd14172	598-791	STKc_MAPKAPK3
cd07858	525-792	STKc_TEY_MAPK
cd14146	531-786	STKc_MLK4
cd06652	522-791	STKc_MEKK2
cd06646	525-791	STKc_MAP4K5
cd14024	564-791	PK_TRB3
cd14148	531-779	STKc_MLK2
cd06651	522-793	STKc_MEKK3
cd14022	568-790	PK_TRB2
cd14113	525-791	STKc_Trio_C
cd06645	525-791	STKc_MAP4K3
cd07875	596-802	STKc_JNK1
cd14135	525-791	STKc_PRP4
cd14031	519-790	STKc_WNK3
cd14184	525-790	STKc_DCKL2
cd14190	570-791	STKc_MLCK2
cd14171	563-791	STKc_MAPKAPK5
cd06650	528-792	PKc_MEK1
cd05620	594-792	STKc_nPKC_delta
cd14027	631-784	STKc_RIP1
cd07874	596-797	STKc_JNK3
cd06657	530-791	STKc_PAK4
cd14023	565-790	PK_TRB1
cd05575	529-734	STKc_SGK
cd05633	525-780	STKc_GRK3
cd14212	525-723	PKc_YAK1
cd05593	525-780	STKc_PKB_gamma
cd05594	490-780	STKc_PKB_alpha
cd14183	525-791	STKc_DCKL1
cd06653	553-791	STKc_MEKK3_like_u1
cd05603	529-799	STKc_SGK2
cd05571	627-790	STKc_PKB
cd13988	531-735	STKc_TBK1
cd14223	525-780	STKc_GRK2
cd14129	525-737	STKc_TTBK2
cd05073	529-779	PTKc_Hck
cd05629	525-790	STKc_NDR_like_fungal
cd05602	525-734	STKc_SGK1
cd14150	526-787	STKc_A-Raf
cd14110	525-734	STKc_obscurin_rpt2
cd05055	598-785	PTKc_PDGFR
cd14130	525-737	STKc_TTBK1
cd05591	529-780	STKc_nPKC_epsilon
cd05043	634-787	PTK_Ryk
cd14151	529-787	STKc_B-Raf
cd14060	532-787	STKc_MLTK
cd05039	530-786	PTKc_Csk_like
cd05093	529-785	PTKc_TrkB
cd14025	529-779	STKc_RIP4_like
cd05626	549-790	STKc_LATS2
cd05106	644-779	PTKc_CSF-1R
cd14018	620-781	STKc_PINK1
cd05627	525-792	STKc_NDR2
cd14033	530-790	STKc_WNK4
cd05105	644-785	PTKc_PDGFR_alpha
cd14158	518-734	STKc_IRAK4
cd14115	531-790	STKc_Kalirin_C
cd05067	527-779	PTKc_Lck_Blk
cd14664	531-734	STK_BAK1_like
cd14049	528-724	STKc_EIF2AK1_HRI
cd13968	531-666	PKc_like
cd14062	638-787	STKc_Raf
cd05608	627-790	STKc_GRK1
cd14088	569-791	STKc_CaMK_like
cd05104	644-779	PTKc_Kit
cd05045	557-785	PTKc_RET
cd05619	529-792	STKc_nPKC_theta
cd14112	521-788	STKc_Unc-89_rpt2
cd14109	566-791	PK_Unc-89_rpt1
cd05083	529-785	PTKc_Chk
cd14032	530-790	STKc_WNK2_like
cd14214	631-790	PKc_CLK3
cd13992	531-783	PK_GC
cd14225	525-791	PKc_DYRK4
cd05148	525-779	PTKc_Srm_Brk
cd14127	525-735	STKc_CK1_fungal
cd13991	626-785	STKc_NIK
cd05082	633-785	PTKc_Csk
cd14149	527-787	STKc_C-Raf
cd14063	527-786	PK_KSR
cd14224	525-724	PKc_DYRK2_3
cd05589	638-780	STKc_PKN
cd14147	531-786	STKc_MLK3
cd14030	519-795	STKc_WNK1
cd05068	527-779	PTKc_Frk_like
cd05587	638-780	STKc_cPKC
cd05061	526-792	PTKc_InsR
cd05085	585-785	PTKc_Fer
cd05628	525-734	STKc_NDR1
cd05107	644-786	PTKc_PDGFR_beta
cd13977	568-727	STKc_PDIK1L
cd05069	566-779	PTKc_Yes
cd05034	529-779	PTKc_Src_like
cd05625	569-792	STKc_LATS1
cd05116	529-779	PTKc_Syk
cd05616	525-784	STKc_cPKC_beta
cd14065	531-788	PKc_LIMK_like
cd06649	640-733	PKc_MEK2
cd14000	633-789	STKc_LRRK
cd14159	531-735	STKc_IRAK1
cd05084	578-781	PTKc_Fes
cd13989	531-779	STKc_IKK
cd05113	566-787	PTKc_Btk_Bmx
cd14039	531-779	STKc_IKK_alpha
cd14013	625-697	STKc_SNT7_plant
cd05615	514-780	STKc_cPKC_alpha
cd14213	631-790	PKc_CLK1_4
cd14136	521-730	STKc_SRPK
cd14038	634-779	STKc_IKK_beta
PHA02882	518-746	PHA02882
cd14055	638-781	STKc_TGFbR2_like
cd05111	614-785	PTK_HER3
cd05059	526-786	PTKc_Tec_like
smart00750	644-794	KIND
cd14011	620-792	PK_SCY1_like
cd14203	571-779	PTKc_Src_Fyn_like
cd13998	637-792	STKc_TGFbR-like
PRK14879	621-668	PRK14879
cd05102	644-786	PTKc_VEGFR3
cd05100	644-786	PTKc_FGFR3
cd05114	526-786	PTKc_Tec_Rlk
cd05048	528-741	PTKc_Ror
cd05098	644-786	PTKc_FGFR1
cd14207	644-786	PTKc_VEGFR1
cd05103	644-788	PTKc_VEGFR2
TIGR03724	585-668	arch_bud32
cd05065	644-787	PTKc_EphR_B
cd05070	527-779	PTKc_Fyn
cd05053	526-785	PTKc_FGFR
cd05112	526-786	PTKc_Itk
cd05120	526-668	APH_ChoK_like
cd05062	526-787	PTKc_IGF-1R
cd05057	527-785	PTKc_EGFR_like
cd05056	573-787	PTKc_FAK
cd14015	595-780	STKc_VRK
cd05099	644-785	PTKc_FGFR4
cd13981	630-693	STKc_Bub1_BubR1
cd14153	551-786	PK_KSR2
cd14215	525-750	PKc_CLK2
cd05060	529-785	PTKc_Syk_like
cd14229	525-730	STKc_HIPK3
cd05576	631-790	STKc_RPK118_like
cd13975	566-745	PKc_Dusty
cd05063	529-777	PTKc_EphR_A2
cd05091	545-740	PTKc_Ror2
cd14205	528-785	PTKc_Jak2_rpt2
cd05038	528-785	PTKc_Jak_rpt2
cd14228	525-730	STKc_HIPK1
cd05090	641-740	PTKc_Ror1
cd05101	644-786	PTKc_FGFR2
cd05051	559-792	PTKc_DDR
cd13980	623-786	STKc_Vps15
cd05041	529-786	PTKc_Fes_like
cd14211	569-724	STKc_HIPK
cd14056	642-697	STKc_TGFbR_I
COG3642	633-668	Bud32
cd14001	528-727	PKc_TOPK
cd05050	644-785	PTKc_Musk
cd13974	635-788	STKc_SHIK
cd05109	643-786	PTKc_HER2
cd14227	571-730	STKc_HIPK2
cd14026	643-764	STKc_RIP2
cd05071	566-779	PTKc_Src
cd14144	643-728	STKc_BMPR1
cd05047	531-786	PTKc_Tie
cd05040	536-779	PTKc_Ack_like
cd05087	528-785	PTKc_Aatyk1
cd05033	526-787	PTKc_EphR
cd05046	528-787	PTK_CCK4
cd07867	530-724	STKc_CDC2L6
cd14054	636-725	STKc_BMPR2_AMHR2
cd05066	642-740	PTKc_EphR_A
cd14152	604-786	STKc_KSR1
cd05044	596-781	PTKc_c-ros
COG0510	569-665	CotS
smart00220	525-791	S_TKc
pfam00069	525-791	Pkinase
COG0515	525-794	SPS1
pfam07714	527-786	Pkinase_Tyr
smart00221	526-779	STYKc
smart00219	526-779	TyrKc
PLN00009	525-790	PLN00009
PLN00034	510-791	PLN00034
PTZ00024	519-797	PTZ00024
PTZ00267	585-812	PTZ00267
PTZ00036	523-803	PTZ00036
PTZ00283	525-789	PTZ00283
PTZ00266	525-804	PTZ00266
PRK13184	635-792	pknD
PTZ00263	625-790	PTZ00263
PHA03210	570-795	PHA03210
PHA03207	571-757	PHA03207
PHA03390	586-797	pk1
PLN03224	625-695	PLN03224
PHA03209	594-764	PHA03209
PTZ00426	586-779	PTZ00426
PRK09605	633-668	PRK09605
PLN03225	629-697	PLN03225
PHA02988	565-786	PHA02988
TIGR03903	568-779	TOMM_kin_cyc
COG0661	557-675	AarF

Ontology Information

HPRD ID	4828
Molecular Class	Dual specificity kinase
Molecular Function	Receptor signaling complex scaffold activity (GO:0030159)
Biological Process	Apoptosis (GO:0006915)

SNP Information

View SNP Geneview Report