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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
MAGED4 728239 melanoma antigen family D, 4  XMAGE1, MGC3210, KIAA1859, MAGE-E1 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
25120768   2014Cell line : -

Source : First Affiliated Hospital of Guangxi Medical University

Sample Type : CRC tumor and normal tissue

No. of Sample : 64

Stage : -

RT-PCR, Immunohistochemistry, ELISAUp-regulation-MAGE-D4 may serve as a potentially prognostic biomarker and an attractive target of immunotherapy in CRC.

MAGE-D4 mRNA was more frequently expressed in CRCs than in adjacent non-tumor tissues.


Gene Details



Chromosome X - NC_000023.11 (52184823..52192268)

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Gene Type protein coding
Gene Family
Description -  
Chromosome X
Location Xp11
Start 52184823  
End 52192268  
Strand +  
Gene Sequence

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Length 7446  
OMIM ID 300702   
HGNC ID HGNC:23793   
Unigene ID Hs.522650   
Ensembl ID ENSG00000154545   
PharmGKB ID -   

mRNA Information


mRNA ID NM_001272061.1
Exon join(1..143,1049..1310,1575..2408,2820..3023,3127..3190, 3384..3463,3852..3943,4565..4644,4730..4772,5164..5226, 5523..5570,6172..6286,6609..7039,7235..7446)  
mRNA Sequence

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Length 2600  



CDS Information


   
Location join(1101..1310,1575..2408,2820..3023,3127..3190, 3384..3463,3852..3943,4565..4644,4730..4772,5164..5226, 5523..5570,6172..6286,6609..7039,7235..7244)
CDS Sequence

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CCDS ID CCDS65261.1



Protein Information


      
Protein IDNP_001258991.1
Protein Namemelanoma antigen family D, 4
Molecular Wt. (Da)81247
Protein Sequence

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Length 741  
Uniprot IDO60449
Ensembl Protein ID ENSP00000263636  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


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No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam01454420-589  MAGE
cl03220420-589  MAGE superfamily
PRK14951138-282  PRK14951
PRK12323132-286  PRK12323
PHA03247138-399  PHA03247
PHA03247136-323  PHA03247
PRK12323140-399  PRK12323
PHA03247138-398  PHA03247
PHA03247129-396  PHA03247
PHA03269135-229  PHA03269
PRK07003197-378  PRK07003
PRK07764153-286  PRK07764
PRK10905133-210  PRK10905
PRK1232393-292  PRK12323
PRK07764141-281  PRK07764
PRK08691145-401  PRK08691
PHA03247149-412  PHA03247
COG3170146-224  FimV


Ontology Information


   
HPRD ID1301
Molecular ClassUnclassified
Molecular FunctionProtein-tyrosine kinase activity (GO:0004713)
Biological ProcessCell communication (GO:0007154); Signal transduction (GO:0007165)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO