Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| WNT7A | 7476 | wingless-type MMTV integration site family, member 7A | 3 | - |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 11311491 | 2001 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | qRT-PCR | Up-regulation | - | Wnts 2, 4, 5a, 6 and/or 7a were found to be more highly expressed in colon carcinoma tissue. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Wingless-type MMTV integration sites |
| Description | This gene is a member of the WNT gene family, which consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is involved in the development of the anterior-posterior axis in the female reproductive tract, and also plays a critical role in uterine smooth muscle pattering and maintenance of adult uterine function. Mutations in this gene are associated with Fuhrmann and Al-Awadi/Raas-Rothschild/Schinzel phocomelia syndromes. [provided by RefSeq, Jul 2008] |
| Chromosome | 3 |
| Location | 3p25 |
| Start | 13860082 |
| End | 13921618 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 61537 |
| OMIM ID | 601570 |
| HGNC ID | HGNC:12786 |
| Unigene ID | Hs.72290 |
| Ensembl ID | ENSG00000154764 |
| PharmGKB ID | PA37387 |
mRNA Information
| mRNA ID | ?NM_004625.3 |
|---|---|
| Exon | join(1985..2046,2195..2267,4949..5175,25319..25590, 60699..61905) | mRNA Sequence | Download Select all |
| Length | 1841 |
Protein Information
| Protein ID | NP_004616.2 |
|---|---|
| Protein Name | wingless-type MMTV integration site family, member 7A |
| Molecular Wt. (Da) | 39230 |
| Protein Sequence | Download Select all |
| Length | 349 |
| Uniprot ID | Q9UNE7 |
| Ensembl Protein ID | ENSP00000219548 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 7855 | FZD5 | 3427 | NP_003459.2 | in vivo | 12857724 |
| 8326 | FZD9 | 3460 | NP_003499.1 | in vivo | 15705594 |
| 29888 | STRN4 | 18125 | NP_001034966.1 | yeast 2-hybrid | 16169070 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Basal cell carcinoma | hsa05217 |
| Hedgehog signaling pathway | hsa04340 |
| Hippo signaling pathway | hsa04390 |
| HTLV-I infection | hsa05166 |
| Melanogenesis | hsa04916 |
| Pathways in cancer | hsa05200 |
| Proteoglycans in cancer | hsa05205 |
| Signaling pathways regulating pluripotency of stem cells | hsa04550 |
| Wnt signaling pathway | hsa04310 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam00110 | 37-349 | wnt |
| cl19568 | 37-349 | wnt superfamily |
| smart00097 | 40-349 | WNT1 |
Ontology Information
| HPRD ID | 5069 |
|---|---|
| Molecular Class | Ligand |
| Molecular Function | Structural molecule activity (GO:0005198) |
| Biological Process | Cell growth and/or maintenance (GO:0008151) |
Drug Information
No matching records could be found.