Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| WNT11 | 7481 | wingless-type MMTV integration site family, member 11 | 11 | - |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 22161723 | 2013 | Cell line : HCT 116 Source : - Sample Type : - No. of Sample : - Stage : Stage I, II, III, IV | real time RT-PCR,Western blotting | Up-regulation | - | Expression levels of Wnt11 mRNA with those of FZD7 mRNA in the same CRC samples. |
| 24504536 | 2014 | Cell line : - Source : GSE23878 dataset from Gene Expression Omnibus. Sample Type : - No. of Sample : - Stage : - | Screening of Differentially expressed Gene, Functional enrichment analysis | Up-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Wingless-type MMTV integration sites |
| Description | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome. [provided by RefSeq, Jul 2008] |
| Chromosome | 11 |
| Location | 11q13.5 |
| Start | 75897370 |
| End | 75921803 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 24434 |
| OMIM ID | 603699 |
| HGNC ID | HGNC:12776 |
| Unigene ID | Hs.108219 |
| Ensembl ID | ENSG00000085741 |
| PharmGKB ID | PA37378 |
mRNA Information
| mRNA ID | ?NM_004626.2 |
|---|---|
| Exon | join(7479..7684,17291..17526,19165..19442,22153..22445, 26770..27683) | mRNA Sequence | Download Select all |
| Length | 1927 |
Protein Information
| Protein ID | NP_004617.2 |
|---|---|
| Protein Name | wingless-type MMTV integration site family, member 11 |
| Molecular Wt. (Da) | 41699 |
| Protein Sequence | Download Select all |
| Length | 354 |
| Uniprot ID | Q13422 |
| Ensembl Protein ID | ENSP00000331614 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Basal cell carcinoma | hsa05217 |
| Hedgehog signaling pathway | hsa04340 |
| Hippo signaling pathway | hsa04390 |
| HTLV-I infection | hsa05166 |
| Melanogenesis | hsa04916 |
| Pathways in cancer | hsa05200 |
| Proteoglycans in cancer | hsa05205 |
| Signaling pathways regulating pluripotency of stem cells | hsa04550 |
| Wnt signaling pathway | hsa04310 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| smart00097 | 47-354 | WNT1 |
| cl19568 | 47-354 | wnt superfamily |
| pfam00110 | 44-354 | wnt |
Ontology Information
| HPRD ID | 12548 |
|---|---|
| Molecular Class | Ligand |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.