Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| ZAP70 | 7535 | zeta-chain (TCR) associated protein kinase 70kDa | 2 | ZAP-70, STD |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21344162 | 2011 | Cell line : COLO205, T84, HCT116, SW480, SW403 Source : ATCC Sample Type : - No. of Sample : - Stage : - | Oligonucleotide microarray and the DAVID bioinformatics method,ATPLite assay,membrane arrays and RT-PCR | Up-regulation | - | CDC25A, VAV1, TP73, BRCA1 and ZAP70 may be novel markers for predicting the effectiveness of radiotherapy in CRC patients. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | SH2 domain containing |
| Description | This gene encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in this gene cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Chromosome | 2 |
| Location | 2q11-q13 |
| Start | 98330031 |
| End | 98356990 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 26960 |
| OMIM ID | 176947 |
| HGNC ID | HGNC:12858 |
| Unigene ID | Hs.234569 |
| Ensembl ID | ENSG00000115085 |
| PharmGKB ID | PA37447 |
mRNA Information
| mRNA ID | ?NM_001079.3 |
|---|---|
| Exon | join(1..107,349..427,10449..10871,11525..11685, 19316..19454,19558..19645,19730..19776,19977..20028, 20953..21145,21683..21889,23906..24098,24190..24330, 24428..24540,25808..26293) | mRNA Sequence | Download Select all |
| Length | 2450 |
Protein Information
| Protein ID | NP_001070.2 |
|---|---|
| Protein Name | zeta-chain (TCR) associated protein kinase 70kDa |
| Molecular Wt. (Da) | 90391 |
| Protein Sequence | Download Select all |
| Length | 619 |
| Uniprot ID | P46937 |
| Ensembl Protein ID | ENSP00000282441 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 289 |
| T | Phosphorylation | 293 |
| T | Phosphorylation | 494 |
| T | Phosphorylation | 187 |
| Y | Phosphorylation | 126 |
| Y | Phosphorylation | 292 |
| Y | Phosphorylation | 315 |
| Y | Phosphorylation | 319 |
| Y | Phosphorylation | 12 |
| Y | Phosphorylation | 8 |
| Y | Phosphorylation | 167 |
| Y | Dephosphorylation | 292 |
| Y | Phosphorylation | 178 |
| Y | Phosphorylation | 319 |
| Y | Phosphorylation | 474 |
| Y | Phosphorylation | 492 |
| Y | Phosphorylation | 493 |
| Y | Phosphorylation | 69 |
| Y | Phosphorylation | 12 |
| Y | Phosphorylation | 167 |
| Y | Phosphorylation | 185 |
| Y | Phosphorylation | 186 |
| Y | Dephosphorylation | 493 |
| Y | Phosphorylation | 248;- |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 867 | CBL | 1320 | NP_005179.2 | in vitro;in vivo | 11 133 830 100 744 300 000 000 |
| 921 | CD5 | 1078 | NP_055022.2 | in vivo | 9378960 |
| 1398 | CRK | 1267 | NP_058431.2 | in vitro;in vivo | 1 041 945 516 339 550 |
| 1845 | DUSP3 | 2553 | NP_004081.1 | in vivo | 12447358 |
| 2214 | FCGR3A | 903 | NP_000560.5 | in vitro | 7819147 |
| 2534 | FYN | 655 | NP_002028.1 | in vivo | 7760813 |
| 3937 | LCP2 | 3362 | NP_005556.1 | in vitro;in vivo | 8 702 662 904 723 710 000 000 |
| 4582 | MUC1 | 1152 | P15941 | in vitro | 14766232 |
| 5335 | PLCG1 | 1398 | NP_002651.2 | in vitro;in vivo | 7629168 |
| 5777 | PTPN6 | 1475 | NP_536859.1 | in vitro | 863 816 210 458 769 |
| 5788 | PTPRC | 1050 | NP_002829.2 | in vitro | 7737297 |
| 5921 | RASA1 | 745 | NP_002881.1 | in vivo | 7760813 |
| 7409 | VAV1 | 1284 | NP_005419.2 | in vitro;in vivo | 779 826 116 339 550 |
| 7456 | WIPF1 | 3835 | NP_003378.3 | in vivo | 12504004 |
| 9846 | GAB2 | 5866 | NP_036428.1 | in vitro;in vivo | 11572860 |
| 10019 | SH2B3 | 5480 | NP_005466.1 | in vitro | 9169414 |
| 27040 | LAT | 3832 | NP_001014989.2 | in vitro;in vivo | 11368773 |
| 28988 | DBNL | 6588 | NP_001116428.1 | in vitro;in vivo | 14557276 |
| 50619 | DEF6 | 10869 | NP_071330.3 | in vitro;in vivo | 12648457 |
| 54900 | LAX1 | 8312 | NP_060243.2 | in vivo | 12359715 |
| 84433 | CARD11 | 6234 | NP_115791.3 | in vivo | 12154360 |
| 203068 | TUBB | 1852 | NP_001060.1 | in vitro;in vivo | 8530437 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Natural killer cell mediated cytotoxicity | hsa04650 |
| NF-kappa B signaling pathway | hsa04064 |
| Primary immunodeficiency | hsa05340 |
| Ras signaling pathway | hsa04014 |
| T cell receptor signaling pathway | hsa04660 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd05115 | 333-601 | PTKc_Zap-70 |
| cl21453 | 333-601 | PKc_like superfamily |
| cd10402 | 152-255 | SH2_C-SH2_Zap70 |
| cl15255 | 152-255 | SH2 superfamily |
| cd09938 | 8-111 | SH2_N-SH2_Zap70_Syk_like |
| cl15255 | 8-111 | SH2 superfamily |
| cd05060 | 342-598 | PTKc_Syk_like |
| cd05116 | 343-598 | PTKc_Syk |
| cd00192 | 343-594 | PTKc |
| cd05056 | 332-586 | PTKc_FAK |
| cd05040 | 343-586 | PTKc_Ack_like |
| cd05033 | 343-589 | PTKc_EphR |
| cd05034 | 344-586 | PTKc_Src_like |
| cd05057 | 344-586 | PTKc_EGFR_like |
| cd05068 | 344-593 | PTKc_Frk_like |
| cd05039 | 333-593 | PTKc_Csk_like |
| cd05038 | 344-586 | PTKc_Jak_rpt2 |
| cd05041 | 344-591 | PTKc_Fes_like |
| cd05065 | 344-586 | PTKc_EphR_B |
| cd05059 | 343-589 | PTKc_Tec_like |
| cd05063 | 344-586 | PTKc_EphR_A2 |
| cd05066 | 344-586 | PTKc_EphR_A |
| cd05108 | 344-586 | PTKc_EGFR |
| cd05052 | 344-593 | PTKc_Abl |
| cd05067 | 334-586 | PTKc_Lck_Blk |
| cd05085 | 344-595 | PTKc_Fer |
| cd05044 | 344-586 | PTKc_c-ros |
| cd05084 | 343-593 | PTKc_Fes |
| cd05109 | 344-586 | PTKc_HER2 |
| cd05148 | 343-595 | PTKc_Srm_Brk |
| cd05048 | 343-595 | PTKc_Ror |
| cd05072 | 343-586 | PTKc_Lyn |
| cd05112 | 342-586 | PTKc_Itk |
| cd10345 | 162-255 | SH2_C-SH2_Zap70_Syk_like |
| cd05032 | 332-587 | PTKc_InsR_like |
| cd05036 | 334-593 | PTKc_ALK_LTK |
| cd05110 | 344-586 | PTKc_HER4 |
| cd13999 | 344-593 | STKc_MAP3K-like |
| cd05083 | 344-593 | PTKc_Chk |
| cd05035 | 344-586 | PTKc_TAM |
| cd05075 | 344-600 | PTKc_Axl |
| cd14203 | 343-586 | PTKc_Src_Fyn_like |
| cd05053 | 327-589 | PTKc_FGFR |
| cd05051 | 366-586 | PTKc_DDR |
| cd05050 | 343-589 | PTKc_Musk |
| cd05049 | 332-595 | PTKc_Trk |
| cd05079 | 328-586 | PTKc_Jak1_rpt2 |
| cd05074 | 344-595 | PTKc_Tyro3 |
| cd05113 | 321-586 | PTKc_Btk_Bmx |
| cd05073 | 341-586 | PTKc_Hck |
| cd05111 | 322-586 | PTK_HER3 |
| cd05099 | 327-594 | PTKc_FGFR4 |
| cd05064 | 344-586 | PTKc_EphR_A10 |
| cd05082 | 344-594 | PTKc_Csk |
| cd14204 | 336-600 | PTKc_Mer |
| cd05114 | 343-587 | PTKc_Tec_Rlk |
| cd05081 | 344-595 | PTKc_Jak3_rpt2 |
| cd05090 | 343-595 | PTKc_Ror1 |
| cd05055 | 319-587 | PTKc_PDGFR |
| cd05058 | 344-597 | PTKc_Met_Ron |
| cd05092 | 343-595 | PTKc_TrkA |
| cd14205 | 343-591 | PTKc_Jak2_rpt2 |
| cd05045 | 338-586 | PTKc_RET |
| cd05091 | 343-595 | PTKc_Ror2 |
| cd05070 | 332-586 | PTKc_Fyn |
| cd05071 | 341-586 | PTKc_Src |
| cd05097 | 334-594 | PTKc_DDR_like |
| cd05069 | 341-609 | PTKc_Yes |
| cd05047 | 344-586 | PTKc_Tie |
| cd05080 | 343-586 | PTKc_Tyk2_rpt2 |
| cd05046 | 342-586 | PTK_CCK4 |
| cd05061 | 343-594 | PTKc_InsR |
| cd05096 | 332-586 | PTKc_DDR1 |
| cd05101 | 309-586 | PTKc_FGFR2 |
| cd05095 | 343-593 | PTKc_DDR2 |
| cd00180 | 344-593 | PKc |
| cd05043 | 347-586 | PTK_Ryk |
| cd05098 | 326-586 | PTKc_FGFR1 |
| cd05089 | 344-601 | PTKc_Tie1 |
| cd05093 | 332-576 | PTKc_TrkB |
| cd14061 | 344-586 | STKc_MLK |
| cd05062 | 343-589 | PTKc_IGF-1R |
| cd05054 | 334-586 | PTKc_VEGFR |
| cd05100 | 327-586 | PTKc_FGFR3 |
| cd05094 | 325-595 | PTKc_TrkC |
| cd05088 | 344-586 | PTKc_Tie2 |
| cd13978 | 344-592 | STKc_RIP |
| cd14148 | 344-595 | STKc_MLK2 |
| cd05106 | 321-591 | PTKc_CSF-1R |
| cd14058 | 344-593 | STKc_TAK1 |
| cd14146 | 344-595 | STKc_MLK4 |
| cd14207 | 344-593 | PTKc_VEGFR1 |
| cd14145 | 344-589 | STKc_MLK1 |
| cd14147 | 344-595 | STKc_MLK3 |
| cd14014 | 343-584 | STKc_PknB_like |
| cd05103 | 334-593 | PTKc_VEGFR2 |
| cd05107 | 315-586 | PTKc_PDGFR_beta |
| cd05104 | 319-593 | PTKc_Kit |
| cd05102 | 334-586 | PTKc_VEGFR3 |
| cd05105 | 315-587 | PTKc_PDGFR_alpha |
| cd05037 | 344-589 | PTK_Jak_rpt1 |
| cd05122 | 342-594 | PKc_STE |
| cd14059 | 344-586 | STKc_MAP3K12_13 |
| cd10401 | 159-255 | SH2_C-SH2_Syk_like |
| cd14003 | 344-573 | STKc_AMPK-like |
| cd06606 | 344-591 | STKc_MAPKKK |
| cd14060 | 345-586 | STKc_MLTK |
| cd06627 | 343-585 | STKc_Cdc7_like |
| cd08215 | 343-585 | STKc_Nek |
| cd14121 | 344-562 | STKc_ULK3 |
| cd05117 | 343-529 | STKc_CAMK |
| cd14206 | 343-577 | PTKc_Aatyk3 |
| cd14008 | 344-568 | STKc_LKB1_CaMKK |
| cd06623 | 343-585 | PKc_MAPKK_plant_like |
| cd05087 | 343-584 | PTKc_Aatyk1 |
| cd14065 | 344-593 | PKc_LIMK_like |
| cd06605 | 343-585 | PKc_MAPKK |
| cd06612 | 344-584 | STKc_MST1_2 |
| cd05042 | 343-584 | PTKc_Aatyk |
| cd14064 | 344-596 | PKc_TNNI3K |
| cd14027 | 381-598 | STKc_RIP1 |
| cd05078 | 338-586 | PTK_Jak2_rpt1 |
| cd14009 | 344-575 | STKc_ATG1_ULK_like |
| cd14066 | 344-593 | STKc_IRAK |
| cd14062 | 344-594 | STKc_Raf |
| cd06609 | 343-568 | STKc_MST3_like |
| cd14073 | 344-602 | STKc_NUAK |
| cd14150 | 344-595 | STKc_A-Raf |
| cd14026 | 347-587 | STKc_RIP2 |
| cd13979 | 343-540 | STKc_Mos |
| cd14155 | 356-593 | PKc_TESK |
| cd06642 | 321-568 | STKc_STK25 |
| cd14154 | 344-600 | STKc_LIMK |
| pfam00017 | Oct-87 | SH2 |
| pfam00017 | 163-238 | SH2 |
| cd08529 | 343-585 | STKc_FA2-like |
| cd14120 | 344-586 | STKc_ULK1_2-like |
| cd14075 | 343-544 | STKc_NIM1 |
| cd14208 | 344-589 | PTK_Jak3_rpt1 |
| cd06641 | 321-568 | STKc_MST3 |
| cd05123 | 344-573 | STKc_AGC |
| smart00252 | 161-245 | SH2 |
| cd05076 | 358-589 | PTK_Tyk2_rpt1 |
| cd14000 | 344-595 | STKc_LRRK |
| cd14025 | 344-589 | STKc_RIP4_like |
| cd14221 | 344-591 | STKc_LIMK1 |
| cd06640 | 321-568 | STKc_MST4 |
| cd06632 | 344-562 | STKc_MEKK1_plant |
| cd14072 | 344-556 | STKc_MARK |
| cd14156 | 356-586 | PKc_LIMK_like_unk |
| cd06917 | 344-574 | STKc_NAK1_like |
| cd06628 | 344-567 | STKc_Byr2_like |
| cd14070 | 344-577 | STKc_HUNK |
| cd14103 | 344-556 | STKc_MLCK |
| cd14079 | 344-545 | STKc_AMPK_alpha |
| cd14663 | 344-573 | STKc_SnRK3 |
| cd14149 | 344-600 | STKc_C-Raf |
| cd13990 | 344-588 | STKc_TLK |
| cd14071 | 341-530 | STKc_SIK |
| cd05581 | 343-549 | STKc_PDK1 |
| cd14105 | 343-540 | STKc_DAPK |
| cd05578 | 345-542 | STKc_Yank1 |
| cd06611 | 343-543 | STKc_SLK_like |
| smart00252 | Sep-93 | SH2 |
| cd14201 | 344-586 | STKc_ULK2 |
| cd13996 | 344-533 | STKc_EIF2AK |
| cd14151 | 344-586 | STKc_B-Raf |
| cd14082 | 340-534 | STKc_PKD |
| cd09938 | 161-254 | SH2_N-SH2_Zap70_Syk_like |
| cd14007 | 344-584 | STKc_Aurora |
| cd14076 | 344-540 | STKc_Kin4 |
| cd14165 | 339-593 | STKc_TSSK1_2-like |
| cd05077 | 361-586 | PTK_Jak1_rpt1 |
| cd13992 | 346-586 | PK_GC |
| cd08217 | 343-585 | STKc_Nek2 |
| cd14202 | 344-586 | STKc_ULK1 |
| cd14162 | 344-540 | STKc_TSSK4-like |
| cd06613 | 343-562 | STKc_MAP4K3_like |
| cd06610 | 366-555 | STKc_OSR1_SPAK |
| cd05086 | 343-598 | PTKc_Aatyk2 |
| cd07829 | 344-526 | STKc_CDK_like |
| cd14006 | 344-534 | STKc_MLCK-like |
| cd14158 | 344-593 | STKc_IRAK4 |
| cd06643 | 343-575 | STKc_SLK |
| cd14084 | 322-540 | STKc_Chk2 |
| cd14069 | 343-561 | STKc_Chk1 |
| cd06620 | 332-540 | PKc_Byr1_like |
| cd06650 | 343-574 | PKc_MEK1 |
| cd14194 | 343-552 | STKc_DAPK1 |
| cd14222 | 344-595 | STKc_LIMK2 |
| cd08222 | 344-576 | STKc_Nek11 |
| cd06617 | 343-591 | PKc_MKK3_6 |
| cd08220 | 344-585 | STKc_Nek8 |
| cd14186 | 344-540 | STKc_PLK4 |
| cd14063 | 337-586 | PK_KSR |
| cd14119 | 344-594 | STKc_LKB1 |
| cd14080 | 344-529 | STKc_TSSK-like |
| cd09935 | 159-251 | SH2_ABL |
| cd14068 | 344-595 | STKc_LRRK2 |
| cd13989 | 344-556 | STKc_IKK |
| cd06621 | 344-549 | PKc_Pek1_like |
| cd06644 | 343-584 | STKc_STK10 |
| cd14196 | 343-540 | STKc_DAPK2 |
| cd08530 | 344-535 | STKc_CNK2-like |
| cd06638 | 344-591 | STKc_myosinIIIA_N |
| cd14081 | 344-567 | STKc_BRSK1_2 |
| cd14002 | 342-540 | STKc_STK36 |
| cd14191 | 341-540 | STKc_MLCK1 |
| cd14198 | 335-540 | STKc_DRAK2 |
| cd07832 | 344-533 | STKc_CCRK |
| cd14195 | 343-540 | STKc_DAPK3 |
| cd14067 | 344-594 | STKc_LRRK1 |
| cd06622 | 343-586 | PKc_PBS2_like |
| cd14190 | 344-540 | STKc_MLCK2 |
| cd14041 | 344-585 | STKc_TLK2 |
| cd08528 | 344-589 | STKc_Nek10 |
| cd06614 | 344-552 | STKc_PAK |
| cd14106 | 343-540 | STKc_DRAK |
| cd06618 | 343-586 | PKc_MKK7 |
| cd06629 | 386-584 | STKc_Bck1_like |
| cd06608 | 343-594 | STKc_myosinIII_N_like |
| cd07841 | 344-540 | STKc_CDK7 |
| cd00173 | 162-239 | SH2 |
| cd14047 | 343-534 | STKc_EIF2AK2_PKR |
| cd14161 | 344-602 | STKc_NUAK2 |
| cd14197 | 343-540 | STKc_DRAK1 |
| cd05592 | 344-540 | STKc_nPKC_theta_like |
| cd07836 | 343-534 | STKc_Pho85 |
| cd05615 | 335-540 | STKc_cPKC_alpha |
| cd14038 | 344-540 | STKc_IKK_beta |
| cd14116 | 344-541 | STKc_Aurora-A |
| cd14192 | 344-552 | STKc_MLCK3 |
| cd06649 | 343-539 | PKc_MEK2 |
| cd06624 | 342-551 | STKc_ASK |
| cd10348 | 163-246 | SH2_Cterm_shark_like |
| cd05579 | 347-534 | STKc_MAST_like |
| cd14137 | 345-533 | STKc_GSK3 |
| cd05582 | 344-556 | STKc_RSK_N |
| cd14098 | 344-526 | STKc_Rad53_Cds1 |
| cd14039 | 344-540 | STKc_IKK_alpha |
| cd05573 | 344-540 | STKc_ROCK_NDR_like |
| cd06616 | 343-586 | PKc_MKK4 |
| cd06615 | 343-573 | PKc_MEK |
| cd08225 | 344-592 | STKc_Nek5 |
| cd14078 | 343-540 | STKc_MELK |
| cd14167 | 334-540 | STKc_CaMKI_alpha |
| cd07840 | 343-531 | STKc_CDK9_like |
| cd14193 | 344-540 | STKc_MLCK4 |
| cd05611 | 347-556 | STKc_Rim15_like |
| cd14664 | 344-547 | STK_BAK1_like |
| cd06639 | 344-584 | STKc_myosinIIIB_N |
| cd13994 | 344-595 | STKc_HAL4_like |
| cd06631 | 344-565 | STKc_YSK4 |
| cd05118 | 344-534 | STKc_CMGC |
| cd13987 | 344-540 | STKc_SBK1 |
| cd06633 | 321-554 | STKc_TAO3 |
| cd06625 | 344-584 | STKc_MEKK3_like |
| cd14093 | 344-595 | STKc_PhKG |
| cd06630 | 344-584 | STKc_MEKK1 |
| cd05584 | 344-540 | STKc_p70S6K |
| cd05580 | 343-540 | STKc_PKA_like |
| cd05616 | 344-563 | STKc_cPKC_beta |
| cd13988 | 344-556 | STKc_TBK1 |
| cd07860 | 343-526 | STKc_CDK2_3 |
| cd07838 | 343-531 | STKc_CDK4_6_like |
| cd13998 | 345-593 | STKc_TGFbR-like |
| cd13982 | 336-585 | STKc_IRE1 |
| cd07865 | 344-531 | STKc_CDK9 |
| cd05587 | 344-540 | STKc_cPKC |
| cd14077 | 344-556 | STKc_Kin1_2 |
| cd05595 | 344-573 | STKc_PKB_beta |
| cd14097 | 344-540 | STKc_STK33 |
| cd08223 | 344-585 | STKc_Nek4 |
| cd14095 | 344-530 | STKc_DCKL |
| cd06619 | 344-545 | PKc_MKK5 |
| cd05619 | 344-561 | STKc_nPKC_theta |
| cd00173 | Sep-87 | SH2 |
| cd09940 | 162-238 | SH2_Vav_family |
| cd14152 | 344-586 | STKc_KSR1 |
| cd14040 | 344-585 | STKc_TLK1 |
| cd05570 | 344-541 | STKc_PKC |
| cd05613 | 367-574 | STKc_MSK1_N |
| cd14083 | 344-527 | STKc_CaMKI |
| cd08221 | 408-584 | STKc_Nek9 |
| cd14091 | 343-556 | STKc_RSK_C |
| cd07830 | 343-531 | STKc_MAK_like |
| cd14153 | 344-587 | PK_KSR2 |
| cd08219 | 344-592 | STKc_Nek3 |
| cd14164 | 344-540 | STKc_TSSK6-like |
| cd05631 | 344-544 | STKc_GRK4 |
| cd05583 | 344-540 | STKc_MSK_N |
| cd05620 | 344-540 | STKc_nPKC_delta |
| cd05607 | 344-544 | STKc_GRK7 |
| cd05618 | 344-540 | STKc_aPKC_iota |
| cd14048 | 344-533 | STKc_EIF2AK3_PERK |
| cd08228 | 343-591 | STKc_Nek6 |
| cd14087 | 344-540 | STKc_PSKH1 |
| cd14043 | 439-586 | PK_GC-2D |
| cd14163 | 344-555 | STKc_TSSK3-like |
| cd05624 | 328-540 | STKc_MRCK_beta |
| cd14012 | 346-575 | PK_eIF2AK_GCN2_rpt1 |
| cd05590 | 344-541 | STKc_nPKC_eta |
| cd07863 | 343-539 | STKc_CDK4 |
| cd06635 | 325-556 | STKc_TAO1 |
| cd06634 | 321-556 | STKc_TAO2 |
| cd14099 | 344-540 | STKc_PLK |
| cd09944 | 158-254 | SH2_Grb7_family |
| cd14114 | 343-540 | STKc_Twitchin_like |
| cd14209 | 344-540 | STKc_PKA |
| cd14117 | 344-541 | STKc_Aurora-B_like |
| cd14200 | 373-540 | STKc_CaMKK1 |
| cd14086 | 343-530 | STKc_CaMKII |
| cd14665 | 338-547 | STKc_SnRK2-3 |
| cd14113 | 343-540 | STKc_Trio_C |
| cd05617 | 344-540 | STKc_aPKC_zeta |
| cd05599 | 345-564 | STKc_NDR_like |
| cd05630 | 344-556 | STKc_GRK6 |
| cd07864 | 344-539 | STKc_CDK12 |
| cd14185 | 344-562 | STKc_DCKL3 |
| cd05614 | 344-574 | STKc_MSK2_N |
| cd14179 | 331-555 | STKc_MSK1_C |
| cd09932 | 158-238 | SH2_C-SH2_PLC_gamma_like |
| cd05589 | 344-540 | STKc_PKN |
| cd06607 | 343-554 | STKc_TAO |
| cd09937 | 161-253 | SH2_csk_like |
| cd14181 | 344-585 | STKc_PhKG2 |
| cd14118 | 343-549 | STKc_CAMKK |
| cd07833 | 343-537 | STKc_CDKL |
| cd10370 | 159-246 | SH2_Src_Src42 |
| cd14010 | 343-540 | STKc_ULK4 |
| cd14175 | 344-556 | STKc_RSK1_C |
| cd14104 | 343-540 | STKc_Titin |
| cd07845 | 356-533 | STKc_CDK10 |
| cd14096 | 344-533 | STKc_RCK1-like |
| cd14131 | 344-594 | PKc_Mps1 |
| cd05598 | 344-540 | STKc_LATS |
| cd10401 | 8-105 | SH2_C-SH2_Syk_like |
| cd14133 | 344-531 | PKc_DYRK_like |
| cd14183 | 344-541 | STKc_DCKL1 |
| cd06655 | 365-540 | STKc_PAK2 |
| cd14166 | 344-540 | STKc_CaMKI_gamma |
| cd14094 | 344-540 | STKc_CASK |
| cd14052 | 344-532 | PTKc_Wee1_fungi |
| cd08218 | 344-584 | STKc_Nek1 |
| cd05572 | 344-533 | STKc_cGK |
| cd07870 | 343-616 | STKc_PFTAIRE2 |
| cd05632 | 344-544 | STKc_GRK5 |
| cd07843 | 356-534 | STKc_CDC2L1 |
| cd09933 | 162-253 | SH2_Src_family |
| cd13997 | 344-534 | PKc_Wee1_like |
| cd14176 | 343-556 | STKc_RSK2_C |
| cd06647 | 365-540 | STKc_PAK_I |
| cd07861 | 343-526 | STKc_CDK1_euk |
| cd06626 | 345-584 | STKc_MEKK4 |
| cd07834 | 344-539 | STKc_MAPK |
| cd14662 | 343-546 | STKc_SnRK2 |
| cd07873 | 343-552 | STKc_PCTAIRE1 |
| cd14044 | 353-590 | PK_GC-C |
| cd14074 | 344-568 | STKc_SNRK |
| cd14199 | 381-540 | STKc_CaMKK2 |
| cd05574 | 344-541 | STKc_phototropin_like |
| cd14184 | 344-541 | STKc_DCKL2 |
| cd10370 | 9-101 | SH2_Src_Src42 |
| cd14178 | 343-556 | STKc_RSK3_C |
| cd07851 | 344-533 | STKc_p38 |
| cd05577 | 344-544 | STKc_GRK |
| cd05623 | 307-540 | STKc_MRCK_alpha |
| cd07857 | 343-544 | STKc_MPK1 |
| cd14089 | 344-545 | STKc_MAPKAPK |
| cd05603 | 344-540 | STKc_SGK2 |
| cd14042 | 346-594 | PK_GC-A_B |
| cd14054 | 344-593 | STKc_BMPR2_AMHR2 |
| cd07862 | 343-531 | STKc_CDK6 |
| cd10361 | 157-240 | SH2_Fps_family |
| cd06654 | 343-540 | STKc_PAK1 |
| cd14109 | 381-556 | PK_Unc-89_rpt1 |
| cd14001 | 356-534 | PKc_TOPK |
| cd14092 | 344-555 | STKc_MSK_C |
| cd07846 | 348-534 | STKc_CDKL2_3 |
| cd10419 | 163-250 | SH2_Src_Fyn_isoform_b_like |
| cd07871 | 343-531 | STKc_PCTAIRE3 |
| cd09944 | 9-104 | SH2_Grb7_family |
| cd07839 | 343-539 | STKc_CDK5 |
| cd10418 | 163-255 | SH2_Src_Fyn_isoform_a_like |
| cd07856 | 344-533 | STKc_Sty1_Hog1 |
| cd05591 | 344-541 | STKc_nPKC_epsilon |
| cd06656 | 343-540 | STKc_PAK3 |
| cd10368 | 163-250 | SH2_Src_Fyn |
| cd10414 | 158-254 | SH2_Grb14 |
| cd09941 | 162-238 | SH2_Grb2_like |
| cd05601 | 340-540 | STKc_CRIK |
| cd10363 | 159-254 | SH2_Src_HCK |
| cd05571 | 344-540 | STKc_PKB |
| cd13991 | 344-566 | STKc_NIK |
| cd09937 | 7-101 | SH2_csk_like |
| cd05585 | 344-548 | STKc_YPK1_like |
| cd10413 | 9-104 | SH2_Grb7 |
| cd13968 | 344-481 | PKc_like |
| cd10365 | 163-250 | SH2_Src_Src |
| cd05608 | 344-559 | STKc_GRK1 |
| cd14115 | 344-573 | STKc_Kalirin_C |
| cd06648 | 342-540 | STKc_PAK_II |
| cd06645 | 344-531 | STKc_MAP4K3 |
| cd10369 | 159-255 | SH2_Src_Frk |
| cd14110 | 343-534 | STKc_obscurin_rpt2 |
| cd09935 | 9-101 | SH2_ABL |
| cd05612 | 344-540 | STKc_PRKX_like |
| cd10343 | 162-255 | SH2_SHIP |
| cd05605 | 344-544 | STKc_GRK4_like |
| cd05604 | 344-540 | STKc_SGK3 |
| cd06653 | 386-583 | STKc_MEKK3_like_u1 |
| cd06636 | 344-584 | STKc_MAP4K4_6_N |
| cd07869 | 343-544 | STKc_PFTAIRE1 |
| cd05600 | 342-534 | STKc_Sid2p_like |
| cd13985 | 343-594 | STKc_GAK_like |
| cd05610 | 347-484 | STKc_MASTL |
| cd14085 | 356-549 | STKc_CaMKIV |
| cd07878 | 344-573 | STKc_p38beta |
| cd07866 | 341-531 | STKc_BUR1 |
| cd13983 | 341-584 | STKc_WNK |
| cd14108 | 343-540 | STKc_SPEG_rpt1 |
| cd14169 | 344-552 | STKc_CaMKI_beta |
| cd09933 | 9-101 | SH2_Src_family |
| cd14056 | 342-576 | STKc_TGFbR_I |
| cd10413 | 158-254 | SH2_Grb7 |
| cd14177 | 343-556 | STKc_RSK4_C |
| cd05602 | 344-540 | STKc_SGK1 |
| cd07872 | 343-534 | STKc_PCTAIRE2 |
| cd07831 | 356-534 | STKc_MOK |
| cd14180 | 344-556 | STKc_MSK2_C |
| cd10367 | 163-253 | SH2_Src_Fgr |
| cd06652 | 344-568 | STKc_MEKK2 |
| cd14168 | 344-540 | STKc_CaMKI_delta |
| cd10415 | 10-104 | SH2_Grb10 |
| cd13993 | 344-542 | STKc_Pat1_like |
| cd05627 | 344-565 | STKc_NDR2 |
| cd08224 | 343-591 | STKc_Nek6_7 |
| cd14004 | 343-540 | STKc_PASK |
| cd10348 | Oct-94 | SH2_Cterm_shark_like |
| cd05593 | 344-540 | STKc_PKB_gamma |
| cd14172 | 344-558 | STKc_MAPKAPK3 |
| cd10398 | 159-251 | SH2_Tec_Txk |
| cd07848 | 349-537 | STKc_CDKL5 |
| cd05628 | 344-565 | STKc_NDR1 |
| cd07835 | 356-531 | STKc_CDK1_CdkB_like |
| cd06659 | 342-568 | STKc_PAK6 |
| cd07858 | 441-539 | STKc_TEY_MAPK |
| cd06646 | 344-531 | STKc_MAP4K5 |
| cd05594 | 344-573 | STKc_PKB_alpha |
| cd08229 | 343-596 | STKc_Nek7 |
| cd14017 | 343-586 | STKc_TTBK |
| cd14045 | 366-591 | PK_GC_unk |
| cd10360 | 162-238 | SH2_Srm |
| cd10347 | Aug-64 | SH2_Nterm_shark_like |
| cd14170 | 335-558 | STKc_MAPKAPK2 |
| cd10371 | 163-255 | SH2_Src_Blk |
| cd10362 | 159-246 | SH2_Src_Lck |
| cd10414 | 9-104 | SH2_Grb14 |
| cd09934 | 159-251 | SH2_Tec_family |
| cd07877 | 344-534 | STKc_p38alpha |
| cd07880 | 343-534 | STKc_p38gamma |
| cd06651 | 386-539 | STKc_MEKK3 |
| cd14159 | 344-541 | STKc_IRAK1 |
| cd14107 | 343-534 | STKc_obscurin_rpt1 |
| cd14050 | 344-532 | PKc_Myt1 |
| cd05588 | 344-540 | STKc_aPKC |
| cd06637 | 344-543 | STKc_TNIK |
| cd07847 | 344-534 | STKc_CDKL1_4 |
| cd10364 | 159-253 | SH2_Src_Lyn |
| cd14189 | 367-556 | STKc_PLK3 |
| cd09931 | 163-255 | SH2_C-SH2_SHP_like |
| cd14187 | 381-541 | STKc_PLK1 |
| cd05621 | 344-540 | STKc_ROCK2 |
| cd13975 | 409-584 | PKc_Dusty |
| cd10369 | 9-101 | SH2_Src_Frk |
| cd10366 | 163-250 | SH2_Src_Yes |
| cd14053 | 347-534 | STKc_ACVR2 |
| cd06658 | 342-540 | STKc_PAK5 |
| cd09931 | 11-104 | SH2_C-SH2_SHP_like |
| cd07849 | 442-534 | STKc_ERK1_2_like |
| cd10407 | 162-240 | SH2_Vav3 |
| cd07837 | 343-526 | STKc_CdkB_plant |
| cd07859 | 344-534 | STKc_TDY_MAPK |
| cd07853 | 422-534 | STKc_NLK |
| cd14188 | 442-586 | STKc_PLK2 |
| cd14112 | 343-541 | STKc_Unc-89_rpt2 |
| cd14049 | 344-533 | STKc_EIF2AK1_HRI |
| cd14088 | 386-540 | STKc_CaMK_like |
| cd05622 | 326-540 | STKc_ROCK1 |
| cd14046 | 344-484 | STKc_EIF2AK4_GCN2_rpt2 |
| cd05597 | 344-540 | STKc_DMPK_like |
| cd10417 | 9-104 | SH2_SH2D7 |
| cd14182 | 344-585 | STKc_PhKG1 |
| cd05596 | 344-540 | STKc_ROCK |
| cd07879 | 344-534 | STKc_p38delta |
| cd05609 | 347-533 | STKc_MAST |
| cd14033 | 341-559 | STKc_WNK4 |
| cd10352 | 164-247 | SH2_a2chimerin_b2chimerin |
| cd07854 | 344-534 | STKc_MAPK4_6 |
| cd14111 | 410-556 | STKc_SPEG_rpt2 |
| cd14229 | 344-540 | STKc_HIPK3 |
| cd10362 | 9-101 | SH2_Src_Lck |
| cd10415 | 158-254 | SH2_Grb10 |
| cd10360 | Sep-87 | SH2_Srm |
| cd10347 | 161-238 | SH2_Nterm_shark_like |
| cd10361 | Mar-75 | SH2_Fps_family |
| cd09932 | Sep-91 | SH2_C-SH2_PLC_gamma_like |
| cd10364 | 10-101 | SH2_Src_Lyn |
| cd10363 | 10-102 | SH2_Src_HCK |
| cd10352 | Sep-59 | SH2_a2chimerin_b2chimerin |
| cd10368 | 10-101 | SH2_Src_Fyn |
| cd09941 | Sep-71 | SH2_Grb2_like |
| cd09940 | Jun-89 | SH2_Vav_family |
| cd10367 | 10-101 | SH2_Src_Fgr |
| cd09934 | 11-101 | SH2_Tec_family |
| cd10419 | Oct-98 | SH2_Src_Fyn_isoform_b_like |
| cd10417 | 162-255 | SH2_SH2D7 |
| cd10418 | 10-101 | SH2_Src_Fyn_isoform_a_like |
| cd10371 | 10-101 | SH2_Src_Blk |
| cd10343 | 9-104 | SH2_SHIP |
| cd10366 | Oct-94 | SH2_Src_Yes |
| pfam07714 | 338-593 | Pkinase_Tyr |
| smart00219 | 343-593 | TyrKc |
| smart00221 | 338-593 | STYKc |
| smart00220 | 343-586 | S_TKc |
| pfam00069 | 344-586 | Pkinase |
| COG0515 | 343-575 | SPS1 |
| PTZ00263 | 325-540 | PTZ00263 |
| PTZ00267 | 408-584 | PTZ00267 |
| PTZ00024 | 344-539 | PTZ00024 |
| PLN00034 | 268-575 | PLN00034 |
| PTZ00266 | 343-619 | PTZ00266 |
| PTZ00283 | 412-573 | PTZ00283 |
| PTZ00426 | 344-533 | PTZ00426 |
| PHA03209 | 370-535 | PHA03209 |
| TIGR03903 | 366-534 | TOMM_kin_cyc |
| PLN00009 | 356-539 | PLN00009 |
| PTZ00036 | 344-533 | PTZ00036 |
Ontology Information
| HPRD ID | 5081 |
|---|---|
| Molecular Class | Tyrosine kinase |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.