Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| AIMP2 | 7965 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 | 7 | p38, PRO0992, JTV-1, JTV1 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21789020 | 2011 | Cell line : - Source : - Sample Type : CRC Tumor and normal tissue No. of Sample : 104 Stage : TNM stages I-IV | Tissue microarray ,Immunohistochemistry | Down-regulation | - | The decreased expression of AIMP1, AIMP2 and AIMP3 in the GC and CRC tissues compared to the corresponding normal tissues suggested that downregulation of these proteins may be related to inactivation of the tumor suppressor functions of AIMP proteins and might play a role in the development of GC and CRC. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | The JTV1 gene is located on chromosome 7p22 flanked by two genes, HRI and PMS2. JTV1 and HRI overlap slightly and are arranged in a tail-to-tail fashion. JTV1 and PMS2 are separated by approximately 200 base pairs and are arranged head-to-head. JTV1 is transcribed in the opposite direction compared to HRI and PMS2. The function of the JTV1 gene product is unknown. [provided by RefSeq, Jul 2008] |
| Chromosome | 7 |
| Location | 7p22.1 |
| Start | 6048882 |
| End | 6063465 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 14584 |
| OMIM ID | 600859 |
| HGNC ID | HGNC:20609 |
| Unigene ID | Hs.301613 |
| Ensembl ID | ENSG00000106305 |
| PharmGKB ID | PA165617609 |
mRNA Information
| mRNA ID | ?NM_006303.3 |
|---|---|
| Exon | join(1..248,5896..6102,8564..8795,14053..14584) | mRNA Sequence | Download Select all |
| Length | 1236 |
Protein Information
| Protein ID | NP_006294.2 |
|---|---|
| Protein Name | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 320 |
| Uniprot ID | Q92854 |
| Ensembl Protein ID | ENSP00000344923 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| T | Phosphorylation | 186 |
| Y | Phosphorylation | 4 |
| Y | Phosphorylation | 67 |
| S | Phosphorylation | 77 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 2058 | EPRS | 703 | NP_004437.2 | in vivo | 9878398 |
| 2275 | FHL3 | 9101 | NP_004459.2 | yeast 2-hybrid | 16189514 |
| 55885 | LMO3 | 11832 | NP_061110.2 | yeast 2-hybrid | 16189514 |
| 79173 | C19orf57 | 14415 | NP_077299.3 | yeast 2-hybrid | 16189514 |
| 84708 | LNX1 | 17287 | NP_001119800.1 | yeast 2-hybrid | 16189514 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd03200 | 214-309 | GST_C_AIMP2 |
| cl02776 | 214-309 | GST_C_family superfamily |
| cd10289 | 229-309 | GST_C_AaRS_like |
| cd10309 | 230-302 | GST_C_GluProRS_N |
| pfam14497 | 226-308 | GST_C_3 |
| cd03177 | 241-313 | GST_C_Delta_Epsilon |
| cd03189 | 255-308 | GST_C_GTT1_like |
| cd10305 | 232-288 | GST_C_AIMP3 |
| cd03207 | 236-312 | GST_C_8 |
| pfam13410 | 254-304 | GST_C_2 |
| cd03178 | 250-302 | GST_C_Ure2p_like |
| cd10307 | 261-304 | GST_C_MetRS_N |
| cd03206 | 213-312 | GST_C_7 |
| cd03182 | 215-302 | GST_C_GTT2_like |
| cd10291 | 250-302 | GST_C_YfcG_like |
| cd00299 | 253-306 | GST_C_family |
| cd03180 | 243-303 | GST_C_2 |
| cd10306 | 233-309 | GST_C_GluRS_N |
| cd10292 | 259-308 | GST_C_YghU_like |
| PLN02907 | 219-314 | PLN02907 |
| COG0625 | 243-312 | GstA |
| PRK10542 | 256-286 | PRK10542 |
Ontology Information
| HPRD ID | 9354 |
|---|---|
| Molecular Class | Translation regulatory protein |
| Molecular Function | Ubiquitin-specific protease activity (GO:0004843) |
| Biological Process | Protein metabolism (GO:0019538) |
Drug Information
No matching records could be found.