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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 21737648 | 2011 | Cell line : - Source : Showa University Fujikaoka Hospital Sample Type : - No. of Sample : 101 cases CRC Patients Stage : - | real time Rt-PCR | Down-regulation | - | The reduced expression of EGFL8 is closely related to metastastic potential and poor prognosis of CRC, suggesting the down-regulation of EGFL8 as a novel prognostic biomarker for CRC patients |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | |
| Description | - |
| Chromosome | 6 |
| Location | 6p21 |
| Start | 32164605 |
| End | 32168285 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 3681 |
| OMIM ID | 609897 |
| HGNC ID | HGNC:13944 |
| Unigene ID | Hs.731888 |
| Ensembl ID | ENSG00000241404 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_030652.3 |
|---|---|
| Exon | join(1..53,1534..1662,1894..2016,2097..2206,2306..2401, 2483..2653,2746..2825,2899..3052,3306..3681) | mRNA Sequence | Download Select all |
| Length | 1311 |
CDS Information
| Location | join(1562..1662,1894..2016,2097..2206,2306..2401, 2483..2653,2746..2825,2899..3052,3306..3352) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS4743.1 |
Protein Information
| Protein ID | NP_085155.1 |
|---|---|
| Protein Name | EGF-like-domain, multiple 8 |
| Molecular Wt. (Da) | 29685 |
| Protein Sequence | Download Select all |
| Length | 293 |
| Uniprot ID | P15018 |
| Ensembl Protein ID | ENSP00000249075 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
No STRING Network could be found.
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam07546 | 37-104 | EMI |
| cl06535 | 37-104 | EMI superfamily |
| pfam14670 | 155-183 | FXa_inhibition |
| cl21504 | 155-183 | EGF_CA superfamily |
| pfam07645 | 144-183 | EGF_CA |
| smart00179 | 144-183 | EGF_CA |
| cd01475 | 119-182 | vWA_Matrilin |
| cl00057 | 119-182 | vWFA superfamily |
| cd00054 | 144-183 | EGF_CA |
| pfam04516 | 72-107 | CP2 |
| cl04559 | 72-107 | CP2 superfamily |
Ontology Information
| HPRD ID | 1048 |
|---|---|
| Molecular Class | Calcium binding protein |
| Molecular Function | Transmembrane receptor activity (GO:0004888) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.