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General Information
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24025712 | 2013 | Cell line : KM12C,KM12SM Source : I. Fidler (MD Anderson Cancer Center, Houston, TX). Council (CSIC, Madrid, Spain). Sample Type : - No. of Sample : - Stage : - | Fibroblast isolation and culture,Sample preparation and iTRAQ labeling,Peptide fractionation and MS analysis,Mouse cytokine array,Cell proliferation, adhesion, migration, and invasion assays,Immunohistochemistry | Up-regulation | >1.4 fold | CALU and CDH11 as candidate stromal biomarkers of prognostic significance in colon cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | EF-hand domain containing |
| Description | The product of this gene is a calcium-binding protein localized in the endoplasmic reticulum (ER) and it is involved in such ER functions as protein folding and sorting. This protein belongs to a family of multiple EF-hand proteins (CERC) that include reticulocalbin, ERC-55, and Cab45 and the product of this gene. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2008] |
| Chromosome | 7 |
| Location | 7q32 |
| Start | 128379346 |
| End | 128413477 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 34132 |
| OMIM ID | 603420 |
| HGNC ID | HGNC:1458 |
| Unigene ID | Hs.7753 |
| Ensembl ID | ENSG00000128595 |
| PharmGKB ID | PA26047 |
mRNA Information
| mRNA ID | NM_001199671.1 |
|---|---|
| Exon | join(1..141,8262..9076,9282..9513,14971..15164, 19580..19746,20501..20561,28165..28364,29772..34132) | mRNA Sequence | Download Select all |
| Length | 6181 |
Protein Information
| Protein ID | NP_001186600.1 |
|---|---|
| Protein Name | calumenin |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 323 |
| Uniprot ID | P98088 |
| Ensembl Protein ID | ENSP00000485659 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 44;- |
| T | Phosphorylation | 65 |
| S | Phosphorylation | 69 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 325 | APCS | 101 | NP_001630.1 | in vitro | 10631319 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00051 | 157-214 | EFh |
| cl08302 | 157-214 | EFh superfamily |
| cd00051 | 193-258 | EFh |
| cl08302 | 193-258 | EFh superfamily |
| cd00051 | 45-98 | EFh |
| cl08302 | 45-98 | EFh superfamily |
| pfam13499 | 78-132 | EF-hand_7 |
| COG5126 | 159-294 | FRQ1 |
| PTZ00184 | 160-291 | PTZ00184 |
| PLN02964 | 31-128 | PLN02964 |
Ontology Information
| HPRD ID | 5380 |
|---|---|
| Molecular Class | Calcium binding protein |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | DNA repair (GO:0006281) |
Drug Information
No matching records could be found.