CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
CASP2	835	caspase 2, apoptosis-related cysteine peptidase	7	ICH1, PPP1R57, MGC2181

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
16166278	2005	Cell line : - Source : - Sample Type : CRC tumor No. of Sample : Caucasian 200), African 102), and Asian 79 individuals Stage : -	MSI analysis and multiplex PCR,Fragment analysis and statistical evaluation	Mutation	-	CASP2 (CAT25) represents a highly promising marker for early detection of colorectal cancer in HNPCC germ line mutation carriers.

Gene Details

NC_000007.13 (142985308..143004789)
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Gene Type	protein coding
Gene Family	Caspases, "Serine/threonine phosphatases / Protein phosphatase 1, regulatory subunits"
Description	This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Chromosome	7
Location	7q34-q35
Start	142985308
End	143004789
Strand	+
Gene Sequence	>gi\|568815591:143288215-143307696 Homo sapiens chromosome 7, GRCh38.p2 Primary Assembly CTTTTGTCTGTCCGCCGAGCACCCCACTTCACCCCATTGGACCGCGCGGCCGCCGCTAGAGCTCTGCGCC TGCGCACGCACCGGGCCGGGGACTGGGTGGCCTGGTGTGTGGGCGCGGCAGGGCGCAGGCGCAGGCGCAG TGTGCGTCCGCGTCTGAGGGGAGGGATGTGGGGGAAGCGACGGCCCCCGGTTTGTTTGGGCTGTGGGCGG TGCGCAGCGGAGAGCCCGGGAAAAGCGGGAAATGGCGGCGCCGAGCGCGGGGTCTTGGTCCACCTTCCAG CACAAGGAGCTGATGGCCGCTGACAGGGGACGCAGGTAAGTAGGGAACGGTCTTAGGGCTCCTTAGGGGA GCCCAGGGAAGGGGAGCGTGGCCCCCAGGCGTGCGGCCCTGCAGCCCCCTCCCCTCGGAGCCCCGGAAAG CAGCCGTGTCCGCGCTTCCTGCCAAGGGTGGGACGCCCGCCCGAGCCGCTCCGAGCCTGACTCCGCGCAA GGGCCCGCGGGCGGACCTCTTGGCCTTGTCTCTCGTGGGAAAAGACTGCCCCAGCCTCCCTTTGTTCAAC CCACGAGGGTTCTAAAGGGGAGGTCTTTGCAGTCCTGCCCGCTCTTGGGTTCTCTTGAAGATTCTTCATC CTTTCCTCTGGCTCCCTTATGAGGGAAACTATAAAAAGACCATACTCTGTCTCCTTAAAAATCGACGAGA CCTTCTGCAGACCTCGGTGCTCTGCCTGATGTGCATTTGATTTGTATCGATTGTATCATGATCTGCATGG CTTTGCATAGAATGACCAGATTTTCAAAGAAGTCAATACAGGGTTTGGAAATTGAGTACTTTTGGCAGAA CAAGGGGGTTCCTGTGGCTCCGAGTGTCCATGCCTCTGCCCCGGTCATTCCATTTCATGGCAGTCATCAC CCAGGAGAACATTGTAATGCCTCCTGCTCGAGACTGAAGATTAAGGTCTTCGCAAAGGGAACCTGCAGAA GGACACAGAATTAAGACGTAGGAACTCCGTGGTGCCCTTCGCCCCTCCTCCCCTTCCAGTTGTGTCCTGA AATTCTAAATGATTGGAAACTTTTATAATGTTCACGTTTAAGACTCTCATACTACAGAGTAGAGGAAGGA GCGGGTGTGCAGAGGGGGTGATGCTTCAGATTAAAACTAAAGAGTTGATTGAAAATTCAAGTCTGGAACT CGAGAGAGTTAAGAACTATAAGTCAGTAAGTTGCAAGTATGGGTGAGATTGTCTAGGGAAAGGCTCTTTG AAGGGGCGTCCCTAATGGAATATCAATATTAAGGGCAGGCCAAAGGCCCTCTAAAGAAAACAGGAACTGG GTAGGCAGAGAGAAGACTCCCAAAGAATGCTGTCATGGAAACCAGAGGAAGAGAACGATTTAAGGAGCGA ATACTACTGGTAAACTAATGGAAGAAATCTGCTGCACCACTGGTTAGTATCCCAGCTGCAGTGTTATATG TGATCGTTATTACTGCTTTGACGTATTCGAAAGTGATTCATTCTTAAATAGGTTTTTTTATTTGTATAGC TCTTTTTCTTGTAGCCAGTTTTTCCTGAAAGTCTTGGGTAATGGAAATATTACAGTAAAAAGAAGAAAAA ATGGAGTTTCAGACTCATTTTTCCAAACCTCAGATTCATTGGCTGCTTCCAACCCACTTCATCTGTTTTA GGATCCCACCTGCTATCTTAGTTCTCCCAGTTCTTCCAGGACCCAGCTCTTCCCTCTTCTAACTATAAAT CTCTCACCCAATAGCATCTGCAAGCCAAGTGCATCCATTCCATAGATGTGTGGTATTTCACTGACTCTAA GATACACATTTTTTCCCTCCCTTTTTTTTTTTTTTTTTTTTTTTGGACGGAGTCTTTGCTGTGTCACCCA GGCTGGAGTGCAGTGGAATGATCTCAGCTCACTGCAACCTCCATCTCCAAGGTTCAAGCGATTCTCCTGT CTCAGCCTCCCGAGTAGCTAGGACTACAGGCATGCAGCACCACACTCGGCTAATTTTTTGTATTTTTAGT AGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCTGCCCACCTTA GCCTCCCAAAGTGCAGGGATTACAGGCATGAGCCACCGTGCCCGGCCTCCCCTCATGTTTTAACACCTTA GAAATCAGAATGCATTTTAGAGTAGGTTTTTAAGTTATAAATGGAAGTTATTGTATTTTCACTGCTATCA GGTGCCACCCTTCCTGCTGTTACATATGTGGAAAATGTGACGGGGCAGGCTAGAGAACTCTGGATTTATG TAAACTAGGCATGTAGATGACATATTGGCAATAGGATTATTTTAGTTTATAAGCAGAAGCTGATCTCTTT GCAAGCCTGTAGCAAAATTAGCTGGAGGTGACAGCACATGCCTGTAGTCCCAACTACTTGGGAGGCTGAG GCAGGTGGATCGCTTGAGTCCAGGAGTTCTGGGCTATAGTGTGCTATGCCAGTCACGTGTCCACATTAAG TTCAGCATCAGTGTGGTGATGTCCTGGGAGTCAGGGTCCACCAGGTTGCCTAAGGAAGGGTGAACCCGCC CAGGTCAAAAATGGAGCAAGTCAAAACTCCTGTGCTGCTCTGTAATGGGATCATACCTGTGAATAGCCAC TGCACTCCAGCCTGGGTGGCACAGTGAGACTCTTTTAAAGTAAATAGATAAATACCTATCCACTGTGACT TTCTGTCATACTTTCTGCTTATCCACATCTTAACAGGATTCGCCATTTTGTCACTGGAACTTAAAAGTTT TAAAAAACATGTAATTATATGTTTATATCACTAGTGAAAGAGAGTTAGTGTCTGCCTCATTTATTTTCTG TTAAAGCCATTGGCTTGAGTTTTTACCATAGTGTTTTAACCCTCATCTAAGATCATTATAAACTTACATC ACTTTCACCAGCTTAGATAATGTGAGATGTTTTCTGAAATAATTCTCTTTATTAAAATTGGTCTATCAGA GAAGTATTCCTTCTCATAAATATGTGTACTTGGGGGTATTGTTTTGCTTAAGACAGATATTTCCCTCCTC TAGTCAGACCATTCATCTCAGATGATCTCAGCTGAACATAAACCATAAGGAATTAGACATTATTTTCTTA TGATCAATGTGTTCCTGCTTAGTACATCTTTGCTTTAACCAGATTTAAGAAATATGCATAATCTTGGTTA TTGTAAGTCTTATTCTTTTTGTTCTTCCTATTCATGCCTCTTCCACTCCACTCTTCTGTGTCAAATTGTG ACTTGACAGCCTTTCCTTCTACCGTTTATCTGTAGGATATTGGGAGTGTGTGGCATGCATCCTCATCATC AGGAAACTCTAAAAAAGAACCGAGTGGTGCTAGCCAAACAGCTGTTGTTGAGCGAATTGTTAGAACATCT TCTGGAGAAGGACATCATCACCTTGGAAATGAGGGAGCTCATCCAGGTATCTGGAGGCAAAAGAGAGAAG ATAAATTGATCATGGGGTGGGAATAGAGCATGACAAAATATGGAAAGGGTGTCGTATCTTTCTTCCTTTT TTTTTTTTTTTTTTTTGAGACAGAGTCTCTGTCTCCCAGGCTGGAGTACAATGGCGCGATCTTGGCTCAC TGCAGCCTCTGCCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCA GGTGCCACCATGCCTGGCTAATTTTTTGGATTTTTAGTAGAGACAGGGTTTCACTGTGTTAGCCAGGAGG GTGTCGATCTCCTGACCTCATGATCCACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCC ACCACACCCAGCTGGATGTTGTACCTTTCTAAAGAAATGGAAATGCCCTTCTACCGTAGAGCATTTGAGA GAAATGATATATAACTCAAGAATAACAGAAAGGACTTCACCCATACATACACTTTTCCTGTAAAAAGAAT TCTTGGATGAGGACACTACTAGGAAGCTCATGTGGAGAAATAGAATTATAGCTAGAGAAGTAAATATGAT TTCATGTTTTATTCTTGTGTCTTAGGCCAAAGTGGGCAGTTTCAGCCAGAATGTGGAACTCCTCAACTTG CTGCCTAAGAGGGGTCCCCAAGCTTTTGATGCCTTCTGTGAAGCACTGAGGGAGACCAAGCAAGGCCACC TGGAGGATATGTTGCTCACCACCCTTTCTGGGCTTCAGCATGTACTCCCACCGGTATGAAGCTTTAGTAA TATGGGGTGTTGGGAAGGGTTAGTTTGACTGGAAAGGAATTTGTAAGTCAGAGTGAGGGAGACTAGATTT TGTTGTATTTGGACCGGACCACTTCCCTAAGGTCTGTCATCATGAGTTTTGATTTCTTACAGTTGAGCTG TGACTACGACTTGAGTCTCCCTTTTCCGGTGTGTGAGTCCTGTCCCCTTTACAAGAAGCTCCGCCTGTCG ACAGGTGAGAATTGATGGACTAAAAGGGGTCCCAGGCCAGGTGCCACGGCTTACGCCTATAATCCCAGCA CTTTGCGGGGCCAAGGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAA ACCCCGTCTCTACTAAAAATATAAAAACTAGCTGGGCATGGTGGTGGGTGCCTGTAATCCCAGCTACTCG GGAAGCTGGGGCAGGAGAATTGCTAGAACCCAGGAGACGGAGGTTGCAGTGAGCCAACACGGTGCCACCG CACTCCAGCCTTGCCAACAGAGTGAGACTCAGTCTCAAAAAATAAAATAAAATAAAATAAAAAGGAGGGG GGTGTCCCAGATTGACTTCCCCTTTCTTGTCTGGTATCTGGCTTTGTCCTAACATGAGCCCTTTTTTTTG TTTTTTTTTTTTTTTGTTGTGTTTTTTTTCAGAAATAGGGTCTTGTTCTGTCACCCAGGCTGGAATGCAG TGACACCACCATAGCTCACTGCAGCGTTGAACTCCTGGGTTGAAGGGCTCCTCCTGCCTCAGCCTCCCAA GTACCTGGGATTACAGGTGCATGCCACCACACCTAGCTCATTTTTAAATTTTTTGTAGAGAAGGAGTCTC ACTTTGTTACCCAGGCTGGTGTCAAACTTCTGGCCTCAAATGATCCTTCCGCCTTGGCCTCCCAAAGTGC TGGGATTATAGGCGTAAGCCACCATGCCCAGCTGAGACATAGTTTATATTGGGAACAGTTGTCAGTAAAT TTGTTAAGGGCTAGTAGGACAGTTTATGCAGGAGTTTGTGGTTTTTTGTTTTTTTTTTTTCTTGTGATGG AGTCTTGCTCTGTCGTCCAGGCTGTAGTGCAATGGTGCAGTCTCGGCTCACTGCAAACTCTGCCTCCTGG GTTCAAGTGATTCTCCTGCCTCAGCCTCCTGAGTAGCTAGGATTACAGGTGCGTGCCACCATACCCAGCT AATTTTTTGTGTTTTTAGTAAGAGATGGGGTTTCACCATCTCCTGACCTCGTGATCTGCCTGCCTCGGCC TCCCAAAGTGTTGGGATTACAGGCATGAGTCACTGCGCCCGGCCCAGGCAAGGTGTTATTAATAGTTGGT CCATTTCCCTTCCACCCCAGATAACAGTTTTTGTGATAATTGGGCCTTTGAGTAGCATGTATGGGCAGGA AGTTCATGCTCAATTGGCCTCTAAAAAGCTGAATAAGAAAAGACTACATTTGGGGCCACCAGCCTGCTGA TGGAGCATCCTAGTGATTGGAACGAGGCTTTTATCAGCTAGCCCATTCGGTCATTCAGCCAGTTGAGCAT ATGCTTCATGCAGGCTATGTGCAGAGAATCCTTTAGTGAGCTAAAACTAAGAGTCTCTGCCCTCATGAAG CTTACAGGTTTGGGTAGTGAGTGAGACCAATATTTATCACAACCCAGTTGCAAGAGATGTCTGAAGTTAC AATGACATATTAAGATTGATGGTTAAGTTATATACTAGTTTTTTGGTTTTCTGTCTATACCACAGATACT GTGGAACACTCCCTAGACAATAAAGATGGTCCTGTCTGCCTTCAGGTGAAGCCTTGCACTCCTGAATTTT ATCAAACACACTTCCAGCTGGTGAGTTTTTGCATAATGACAAGAGGAAGAGAGTTGGGAAATTAGACACC CTTCCTGGGAACCTGAACTTAGTTTGCATGTACATTTCCTTTCTGCCTTATTAGTCAGAAAGTTGTTACT GGTTAAATGCCTTCTGTGAGCATTTGTCTATTTTTACCTGCTGGAGGTTAAGAAGAAAAATACGATGTCT TTGTTTTCTTGAAATGTCTAATCTAGCCGAGGAATCATCTGTTATCAAGACGCTCATGGTCTAACTGGCC TCTCCTCCACAGGCATATAGGTTGCAGTCTCGGCCTCGTGGCCTAGCACTGGTGTTGAGCAATGTGCACT TCACTGGAGAGAAAGAACTGGAATTTCGCTCTGGAGGGGATGTGGACCACAGTACTCTAGTCACCCTCTT CAAGCTTTTGGGCTATGACGTCCATGTTCTATGTGACCAGACTGCACAGGTACCTGAGGTGGGAAAAATT GACATGTAAATTAGAGGACTGAACAACACTTTGGGACCAGAGACATCGTTTGTTCCTGTGCCTGCTGGGA TATGTCTTAAAAGTTGGTTTATTCTACTTACATTTTTACTCACTCTGTTCTGCCTCTCACCTTGCATTCT AGTAAGAAAGAATTAGGGCCGGCCAGCCATTTTAGTGTTGACATCTCAGGTTGTGGTTTCATAAAGTAAT AATAGTCCACAGTTGGTGTCTCACTTTTTTTTTTTTTTTTAAAGACAGAGTTTAGCTCTGTCACCCAGGC TGGAGTGCAATGGCACGATCTCGGCTCACTGCAACCTCTGCCTACCAGGTTCAAGCGATTCTCCTGCCTC AGCTTCCTGAGTAGCTGGAACTGCAGGCGCATGCAACCATACCTGGCTTATTGTTGTATTTTTAGTAGAG ACGGGGTTTTGCCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCGTCCCCCTCGGCCT CCCAAAGTGCTGGGATTATAGGCATGAGCTACGGCACCTGGCTGGGAAAGTATTCTTAACATTTGTGTAA TCACAAGTCATAGGGTAGATTGTTTGTGGACCAGATTTCTAGAAATTGTAAACATTTTCATTATGGGCTG TTCGTCATTAACCTCAGTTACTGTACTGCACAACTGACTTTGTGACCTTTAGGGTTTCTATTTTGCAATC AATAATGGCCTATTTGTAGATTCATATTCACTCTTTATTTTGATTCCAGAATAGTAGAACTTTCTTCAAC TTGCTTTGAGGTTGTCAGTGGTGAAATTAAAATTGCTAGGAGATTCACTTTGATCTGTTGGGATAGAGGA TCTTTGTTTTCCATTCAGCATTGTCTGTAGTCTTCATTTCTCTTTCTTAGCTGCCCTCCTTCTGTGAGAG TAATTATGTATTTACTATATTTTTGGCAAGGCCAGTTTCATCCACAGGTACCTGGGTGTTGTCCTTTACA TGCTATTTTTGCCAGCTTCCCCCTTGTAGCATATGCAATGTAGTTAAATCCACCCTTGCTTCAAAGCCAT GGCAGCAACAGCTGCTTCAGTCATCAAGTATTCAGGTAGTTTATATGCTTTCCTGAGAAGTCTGCTGGGC ATAAAGGGGCAAAGGGCAGGGTACCAGCCATAATTCCTACAGAAGGTCACTTAACAAAATGTGCAGTGTG TGTGTTTTCTTAGAGGTTTTGGTCTAGCCATGTCTTTTACTAGAAATCTATTATGTCATGGTTTTTCAAG TTGTATGCAGCTGATAAAGGATCTTACATGTCTAATAGTTAAAGATAAAATACTGAGTCACTAAGTCAAC TATATATACTGCTGTTTTCTCAGAGACTGTCAGATTTGGTGAGTTTATGAGCTCACTTCATAAATAGCAT TTCCATTTATGGTAAGCCTGATGCATATTCAGTGACCTATTGGATTCTAATTCTTTGGTTGAATTGCTCT GTAACTGGAATTGCAGTAGAGTTGAACTTCAAGCACCTTATAATGGGGGACTATGTGAGCTGCCACAGAT TTTAAAGATCAGATGAGGGAGTTTTGACATCAGCATAAAAGGAAGTGTGTCCTCTTATATTCCTAACGAC CAAACAAGATTAGAGAAAAAATCTTCTGTCATAGCTAAGAAGAAGAAGCGCCTAGGTAGATATGATCAGA AGGATAAGTGGAGGAGGCAGAACTTAAGCTGGCCTTGAAGGATAGAAGTTACTGAAGCAGAGAGGAGTGG TGAAGCCACCCTAGGCAGGGAGAACAGTATGTGGACAAGAAATGTGTGTGTTATAAACCAGGTAGTTGCA ATGGGTGTCATAATTTGGTACACTGGGCATCTGCACAGAATGCTCTCTTCCTGGTGGGATCTCCCTAGAG AGTCAACTCGTTTATCATATAGCTATTTGGCAAGCAAAGAAACAGAACCAAAAAAAAAAAAAAGATCCTT TTTTCTTTCCCTATCAAATCTTTCTTACTTAAGAGAGGAATTCCATTTAAAAACAGGAAATAGTATAATT AGTCTTAGAGACTCCTCTTCCCCTGATAGTGCTGCAGTGAACATGGGTATTCTCACTGCCCAGATGTTTT CACTTTTCTCTTTGTTATTAAGTTTTTATTGCATCTACTTCATGAGGTTACTAGTTCTAGAATTATGATT TACCCTATGTTAGGAAACGTACTCTTCAAAGTGGAAATTTCCTTTTACCATGTGGTATTGTTTTTTTAGC TTGCATTTGGGTCACAAACTGCTTTGAAAATGTAAGGACAAGCTATGGGTTATCCCTGGAAAATGCAGCT GCCCATATAATTTAGCATATAATTTCAGAGGGTTCACAAGTTACTCTCTTCACATGTCCCCCAACCCCTA GCCAAAAATACACTTAGGAGTTAAGAACCCTGCTATTTATAGAAGTACTGTAATTTTATCAAAAACAAAT CTGCAGATCCTATTTTAAGCTATGCTACTTGTAGAAAAATTCCTCCAAATGTCTAATCCCCATTTATTGA ATGGTTTAGTCTTACTAAGTTTGGTTACAAAGTGCGTGTATTCTTTTTTTGGACATTGTTTTCTATTTAC TGACCTAATCTCACTAAATTCAAAATGCTCGTGATTCGGTGCCCAGGTATATAATTTTTGTTTTCTTTTT TTTTATTTTGAGATGGAGTTTCACTTTTGTTGCCCAGGCTAGAGTGCAATGGCGCGATCTGGGCTCATTG CAACCTCTGCCTCCCAGGTTCAAGCAATTCTCCTGTCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCA TGCCACCACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCATCACATTGGTCAGGCTGGTC TCAAACTCCTGACCTCAGGTGATCCACCCGCCTCGGCCTCCCGAAGTGCTGGGATTACAGGCGTGAGCCA CCGCGCCCGGCCTTTGTTTTCTTCTTTGAGCAAAATTAACTTCTTTAACTATTAAATGTTAAATTCTATT AGCATCAGCTCCAGAGGAACATTCACAGTTATGTATTCTCTTGAAATTATATATTCTTGAAAGAATTTTT TGATTATCTGTCATTACCTTAAGATTTCTATTATTATGGTTTGCTTCTACTTAGAAAATACAGATACTTT TCAACAACACCAGTCTCTTTATTTCTAGTTATATTGCAGACTTTCAAATATTTTATGTAATTGCATCTCA ATTATCTACAAACAGAAGTATTCCGAACAGATCAATTAGTAGCTCTCAAACTTTAACATATCACAGTGTC CTGGAGGGCTTGTTAAAACACATTTTGCTGGAGCCCAAGATTTCACGTTTCTTCCAAGTTCCTGGGTGAT GCTGCTGTTGCTGCTTTAGGGGCCACTCTGAGAACTACTGCAATATGTTATATTATAGAAGTGTGCTTTT TATTTTGGCAGTGTGTGTGATTAAATATATGTGTGTTTTAACTCTTCCACCCAGATAACTTACTTATTTT CATTACATTTTATTCAAGTTTATAATAAAATGAACTTGTTTTCTTTCTGCCCATCTCAGAAGACCCAGAC ATCGTGAATTATAGAGGGAGGCATAGGTTTAAACATGTGTGCCCAATTATTATGCTCTTTAGGTACACAG TATAACCTTCTGATGGATGGACCAAATGCTTAAGGTAGTGCTCTTCATGTATCGCAACTTAGTGCAAGAT AAACAAGATTCTCCAGGCATGGTGGCACATGCCTATGGTCCCAGCTACTCTAGAGGCTGAGGCAAGAAGA TTCCTTGAGCCCAGGAGTTCTAGGCTGTAGTGTGCTATGCTGATCAGGTGTCCAAACTAAGTTCATCATC AATATGGTAACCTCCTGGGAGTGGCGGACCACCAGGTTGCCTAAGGAGGGGTGTACCAGCCCAGGTCAGA AATGGAGCAGGTGAAAACTCCTGTGCTGATCAGTAGTGATCTTACACCTGTAAATAGTCACTGCACTCAA GCCTGGGCAATATAGCAAGATCCTGTCTAAAAAAAAAAAAGATAAACAGGAAAACAGTTCTTAAGTTGGA CTACAACATTGACCAGTAATAGATTTCTTTGAGAAAAATACTCTTTATTCGACATGCACATTGTAATGGC ACATTTTTTGCAATGTGTCCCAGACACAGTGATCGGTTTTTGGTTTTTTTTTTGAGACAGGGTCTCTCTC TGTCACCCAGGCTACAGTGCAGTGGTGCAGTCACAGCTCACTGCAGCCTCAACTTCCTAGGCTCCAGTGA TCCCTCCACCGTAGCCTTTAGAGTAGCTGGGACTATAAGCATGCACCACCATGCCTGGCTAATTTTTTTT TTTAAAGATGGAGTCTTGCTAGGTTGTCCAGGCCAAGTCCTTTGTCATAATATCTCATTTTTATCTTCAC AAACTTAGAGAAAATATCCTCATAATTTTTTTTTATAAAGTGAAAAGTGAGGTCTCAAGGGTCTGAGTAA GCTGTTCCAACTCATGAAGCCAAGGTTCAAACCTAGATTAATCTGAACCCAGGACCTGTGTATGTAATTA CTGCCCTGTACAGAATCCTCCTTCATAGCGTGCTCTTTCTGAAACAAAGCATTTTATACAGTCATCATCA TTATCTCTTGGACACTTAGAATCTTAGAAGACAACATACAAGTATTGCTATTCTCTACTATCATGATGCT GTCACAGAACAGTTTATTTTCGTGTAGCTGAATGTGCATGTTACTTATTCATAGCTACACTTTGAGTCAC CCTTGTGCCATTTATATACAAGGGCAGTTGCTCTAATGAAGGATCTGGTTATGAACAGGGAATTAATCAG AGTTGACCAGCTCATGATTAGCTTCTTTAGTAACTTGCTTTAATCCAGGAGCTGTTTGCCTATCTCAGTG AGTCTGAATCTGTATTCAGAATATTGTGTCTGAACTCATATGCATTTTTCTGGTGAGTCCATAGCTTTCT TTAGTCTCTCAAAAGGTCTCTTCTTTTATCATTGACCACAGGAATATACATAAAGCGTTTTATCTTCTAA TAGCTTAGGGTTTCAAAAAGAAACCAAACTTTGATGCTTATGTTGGTGCTGACCTTAGTGCACAACACTA AACATTCCTTTCTTTTAGGAAATGCAAGAGAAACTGCAGAATTTTGCACAGTTACCTGCACACCGAGTCA CGGACTCCTGCATCGTGGCACTCCTCTCGCATGGTGTGGAGGGCGCCATCTATGGTGTGGATGGGAAACT GCTCCAGGTGCGGATACCCTGGTGGAAGCCAACTGTTGAAACCAGGCTGCTTTACCTCCTGCCTGCTGTC TGTCAAGTGATGGCTACTGTTGCATGTGTAGGACTTAGGAGGCCCCGCTGAATGCTTAACCTCTCTTCTT CCTTCTTTCTTTCTGGCAGCTCCAAGAGGTTTTTCAGCTCTTTGACAACGCCAACTGCCCAAGCCTACAG AACAAACCAAAAATGTTCTTCATCCAGGCCTGCCGTGGAGGTGAGTGCCCTAGCAGACCAGCACCTGGGT GGTGGCTCCTGGGCAGCCTCCCACCAGCTCTCACTTTCCTGTTTGCTCCTCTCAGGTGCTATTGGATCCC TTGGGCACCTCCTTCTGTTCACTGCTGCCACCGCCTCTCTTGCTCTGTAAGTGTCTCCCAATGCATGGGG TGTGCTGGGACTTGGGCAGCCCATGGCTCTCAGGCTGGTCAGCTCTCCGTGCACCACCATATCCTGTTTT CAGGTCTCTTATCCCGTGTCTTTGCCTTCCTTTCTGAGAACTCTTACTCTTTTCTGTGCTTCATTAACTC TGGTGCCCTTTTTTTGGTTACTCATTCCAGTTACGGATTTTTGATCTGTCTTTTTCCTGTCCTTCTTATT TTATCTCCTTTCTTTCACTCTTTGTTCTTTTCACTTGTTCCATATACTTCCCTGTTTACCTACACTTCCA TGCTTGCCTCCTTTCTTCTTTCTTCTTACCATTCTTGGGTCATGCAGGATAGCAGAACAGAATCCGTGTT GGCCTTTGACTCTTCCTTTTCCGTGAGCTGCTGCTGCCCCTCTTTCTCTCATGCAGTCTGTTTTACTCCT TTAAGAGCCAGGACTGCAGGACGAGGATTAAAAGACACATAGGTGTGCTTCTCATCCTGGAGGAAAATAA TAGTAATTAAGAGCCCTAACTTTGGAGTCAAATTCTGACTTCACCATTTACTAGTAACGTGAAGTTAAAG AAGTTAAATGGCATCCCTCCATCTCAGTTTCCTCAATATAAAATGAAAATAGTCCTTGTACCTACTTCAT AAGGTGCTTGTGATGGTTAAATGAGATTATGCATTTAAGGGCTTACATAGCTCAGTACCTGGCTCACAGC ACATCCACAAAATATGCCAGCTGTAACTCTTAAAACACGATCAGTGCCGTAAAGGGCTTATAGTTTGCTT TAAAGGTCACTTTGTCCAAACATTCAAATAATTACTTTTTTAATCTCTCATGTGGCCAAATGTAAATAGC TAATATTATTGTCATCCTGATCTAGTATTACCGCAGAATATAGTCTGCTGAGGCCCTGCAACATGACTCA GACTACGGCAGTTACTACCGCAAAAGCAGAAGGAAATGTGGCCTCTCTAAGGAGCAGACCAGTTACTCAG GAAAATAAAGTAAATATACATGAAGTAGCTTAAGACTAGTTCACAGGCCTCATGTAAGCAAAGGTGAAAT TAGCAAGGTACAAACTGTACTTAGGAAGGAGTATGCAGTAAGAGTAGATCATTTTAAGTGAGGGTAGTTT AAAGAGATTTTTTAGATAAGATAAGGCTTAATTTGTACCTGGAGTAATTTGATTTACATAGTTATAGAGT AGTATCTAGAGTCTGTCGTAGGAAAGAAACAATACAATATGATAAGTACACTGAGAGGCAGAGGGCATGT TGTGTCTCCCCTCCTCCCAAACAGATGCTCGGATCTGATTTTAAAATAGCATCTGTGTGAGTATGTGAGA TGTGGCTGGTCACAATGAAGTGGGTTCACCTCCTTACAAACCTTTAGTCATAACTGAGGTTTTGGACATC AGCAGGTAAAAGTAAGGAACAGTTGGGAGCTTAAGTAAGAAATAATGTGATGAATTGTTTTTCCAGCAAG GTTGCCATGGAGGGGGCTGCACTAAGGAAAGAGGTTATGGGTCAGCAACTTTACTTTTCATTCCCTGCTC TATCCCCAGGCCCAGGGCACTGCCTGATGCATGGTAGCACTTATAAATGTTCAATGAATGGATGAAAATT AATCTGCCTGAAAAACTGTAGGTATTATGTAAAAAACAAATATGAGGATATTGTGACAAAAGAACCAGTG ACATTTATTGATTGATGGATCTGTGATATAAAGGTGAGAGAGGAATTCTCCTTTCTCTTTAGCTTGGCCT GTTTCCTTTAGGCGTCTTTACTAACAAAACGACGTTAAATTGTGATTTTCTCATCCTATATCCAGGGATT TAATACACTATTGGATCTGGATAAGGAGTAATTGCTCTTTTCTGGAGTAATCTGGATCTTTTGCTCTGTC TCTCTAACTTTTCTGAAATTAAATCCTTCAAGGAATGACCAGTAGCCAATTGTTCCATTGAAAATTTGAG TTCACCTGTCTTCCTGCTGTATTTGGTTAATATAATTAATGTCTAGAAAAAGCTCCACCCCCCTGCCCCA GTCAGCTTCTAAACTGGAGTGTAAGCTCCATGACGGCAGGAATTTTCTCTTCACTCTATCCCTAGGCCTT AAAGTAAGACAGTGCCCAACACATGGCAGTTGCTTGACACATTTTTATTAAACCTGTGCTTTGGTCCTTT TCCCCCAATTCTTGAAGCTTCCCTTCTTTCCTAGGCTCCCTCGACATTGCATGGATCAGGAAGTACTGTA AAAGAGCATACTCTTACTTTTGATGTGTTGACCTGAGAGTCCTCCCCATCTGTCTTGCCTACTGACAGCA CCCCTGCCCACACCCAAAATAAAACAACATCATCAAAAATAAGAGTCTGTCTTGGGATACATAAGGCTTG TATCAAGAGCAAGGATCTGCTCAGGGTATGTTGAGAAATTACTGCTAAAATTGAATAAGGATGATCTTTT TAAATTTTCTGGGAGAAAACAGTCAAGTTCTCCCCACTTTAAGTTTTTCCTCTTAAAATTTTCATAAGGC CAGGTGCAGTGACTCATGCCTATAATCCCAACACTTTGGGAGGCCGAGGCAGAAGGATCACTTGAAGCCA GGAGTTCAAGACAAGCCTGGTCAACGTAGCAAGACCCCATCTCTATTAAAAAAAGAAAAAAAAAGATTTA AAAAGTTATTTTAAAAAATAAATTAAAAATTTTTTTTCTTAAATCTTGGATGCTTGCTATAATTTATCTT ATGAAATTAATAAACATAGTGCTTCGAAGATATCAAAACCACCTTGGAAACAACTGATCATACTTAGTTT TATTATTTTTTGATACATAGTTCGAGGTTGTGATTTTTATATAGCATACATATGGTAACCGTATTTGTTA TTTATTACCTTGTTTTTTCTTGTTTATGTAATTAAATATATCAATATTTTATTATGTATTGCAATAAAAA GCACTGTGACTCCCAGGCATATTGTTAATTGAACAAGTGAGTTGTGGACTTAGATGATTTTCAGTTCCAT TTACAAGGAGTATTTGATTTGGCATTTTCCCTGTCTTACACAGAATGGGAACTGCTCCAACCGCATAGAT GTGCATGTGCTTGAGCGTGGTGCCCGGTGTGTATGAGGCATCCCCTGAGTAACAGATGCATGCTGAGAGA GTAATAATTTTTTTTTTTTTTTTTTAGTTTATCAGCCATAGGTTGGAGGCAACAGCTGGAAATGGCTCTT CCCCTTCAAGGTTGTAGGGAACGTGGGCTTGCCTGTGACAGGCCCAAGAGAGATAGGAAGAAGTAACATC ATTGTCCATTCTGTCTGCCTTTGTTACAGATGAGACTGATCGTGGGGTTGACCAACAAGATGGAAAGAAC CACGCAGGATCCCCTGGGTGCGAGGAGAGTGATGCCGGTAAAGAAAAGTTGCCGAAGATGAGACTGCCCA CGCGCTCAGACATGATATGCGGCTATGCCTGCCTCAAAGGTACTTTGAGTTCCAAAAGAGTTGAGTCATA CCTCATTTTGTTGCACTTTGCTTTATTGTGCTTTGCAGGTACAGGTTGAGTATCCCTTATCTGAAGTGTT GGAACCAGAAGTGTTTCAGATTTTGGATTTTTTTGTTTTTTTGGATTTTGGAATATTTGCGTTATACTTA CTAGTTGAGTATCCCGTATCCAAATATTCTAAATTTAAAACACTCCCATGAGCACCTTCTTTGAGCATCA TATTGGCACTTGGAAAGTTTCAGATTTTGAAGCATTTCAGATTTTTTGGATTTGGGATGCTCAGCTGCTT TTTACAAATTGAAGGTTTGTGGCAATCCTTTGAGCATCTGTCAGCACCATTTTTCTATTGGCATGCCTCT GTTAGCATTTTTCAGCAATAAAGTATGTTTTAATTACAGCATATGCATGTTTTAGACATAATGTTGTTGC ACACTTAATAGACTGTAGGATAGTAACCATAACTTCCGTATACACTGGGAGACCTGAAAATTTGTATGAC TTGCTTTATTGCCATATTCACTTTCTTAAGCTGGTCTGGAAACAGACCTACGGTATCTCCAAAGTATGCC AATAATCCAAAAGAGTACCCTCCTAGACTTAGATTCTTCATGCTGGGTTCTCTGACTAGGGAGGGTGCAG GTGTCATGGCCGAGTCTAGTTTGGGAAGTGCAGCTGTGTGATGGCATTCACACTGTGATTAATGCCCTTT TGGTTGCAGGGACTGCCGCCATGCGGAACACCAAACGAGGTTCCTGGTACATCGAGGCTCTTGCTCAAGT GTTTTCTGAGCGGGCTTGTGATATGCACGTGGCCGACATGCTGGTTAAGGTGAGCCAGCGGGCTCCGTGA CCCCTGTGTGTCTCCACAGTGCTCTACTTTCCTCCTCTCTTGAATGCTCTTTCATAGTCCGTCTCCCCTT CCCGTTTGCTGCTCTCCTGAAGCCCGAGATTCTCAGACTTGGGCCTATTGGTTCTGCCCCTCCAGGTGAA CGCACTTATCAAGGATCGGGAAGGTTATGCTCCTGGCACAGAATTCCACCGGTGCAAGGAGATGTCTGAA TACTGCAGCACTCTGTGCCGCCACCTCTACCTGTTCCCAGGACACCCTCCCACATGATGTCACCTCCCCA TCATCCACGCCAAGTGGAAGCCACTGGACCACAGGAGGTGTGATAGAGCCTTTGATCTTCAGGATGCACG GTTTCTGTTCTGCCCCCTCAGGGATGTGGGAATCTCCCAGACTTGTTTCCTGTGCCCATCATCTCTGCCT TTGAGTGTGGGACTCCAGGCCAGCTCCTTTTCTGTGAAGCCCTTTGCCTGTAGAGCCAGCCTTGGTTGGA CCTATTGCCAGGAATGTTTCAGCTGCAGTTGAAGAGCCTGACAAGTGAAGTTGTAAACACAGTGTGGTTA TGGGGAGAGGGCATATAAATTCCCCATATTTGTGTTCAGTTCCAGCTTTTGTAGATGGCACTTTAGTGAT TGCTTTTATTACATTAGTTAAGATGTCTGAGAGACCATCTCCTATCTTTTATTTCATTCATATCCTCCGC CCTTTTTGTCCTAGAGTGAGAGTTTGGAAGGTGTCCAAATTTAATGTAGACATTATCTTTTGGCTCTGAA GAAGCAAACATGACTAGAGACGCACCTTGCTGCAGTGTCCAGAAGCGGCCTGTGCGTTCCCTTCAGTACT GCAGCGCCACCCAGTGGAAGGACACTCTTGGCTCGTTTGGGCTCAAGGCACCGCAGCCTGTCAGCCAACA TTGCCTTGCATTTGTACCTTATTGATCTTTGCCCATGGAAGTCTCAAAGATCTTTCGTTGGTTGTTTCTC TGAGCTTTGTTACTGAAATGAGCCTCGTGGGGAGCATCAGAGAAGGCCAGGAAGAATGGTGTGTTTCCCT AGACTCTGTAACCACCTCTCTGTCTTTTTCCTTCCTGAGAAACGTCCATCTCTCTCCCTTACTATTCCCA CTTTCATTCAATCAACCTGCACTTCATATCTAGATTTCTAGAAAAGCTTCCTAGCTTATCTCCCTGCTTC ATATCTCTCCCTTCTTTACCTTCATTTCATCCTGTTGGCTGCTGCCACCAAATCTGTCTAGAATCCTGCT TTACAGGATCATGTAAATGCTCAAAGATGTAATGTAGTTCTTTGTTCCTGCTTTCTCTTTCAGTATTAAA CTCTCCTTTGATATTATGTGGCTTTTATTTCAGTGCCATACATGTTATTGTTTTCAACCTAGAAACCTTT ATCCCTGCTTATCTGAAACTTCCCAACTTCCCTGTTCTTTAAGACTTTTTTTTTTTTTTTTTTTTTTTTT GAGACAGAGTCTCGCTCTGTCGCCCAGGCTGGAGGGCAGTGGCACGATCTCAGCTCACTGCAAGCTCCAA CTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTTCCAAGTAGCTGGGACTACAGGTGCCCGCCACCGTG CCCGGCTAATTTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTAGCCGGGATGGTCTTGATCTC CTGACCTCATGATCCACCCACCTCAGCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACTGCGCCCGG GCAAGACCTTTTTTTAAAAAAAAAAAAAAAAAAACTTCCATTCTTTCTTCCTCCAGTCTGTTCTCACATA ACAGAGTAGTTTTGGTTTTTAATTTTTTTTGGTTGTTTGCTGTTTTTTGTTTTTTAAGGTGAGTTCTCAC TATGTTTCTCAGACTGGTCTCGAACTCCTGGCCTCAAGCCATCTTCCCGCCTCAGCCTCTCAAATAGCTG GGCTTACAGGCATGAGCCACCACACCTGGCCAGGATTTGGTTGTTTAAATATAAATCTGATCACCCCCCT GCTTAGAACCCTTCTGCTTTCTATTACCCCTCATTTAAAATGTAAACTCTTCACCTTGGTTTATGAGAAC TGGTTCTTGCCTTCCCCTTGAACCTCATTAAATGGTGATTTCTTGCTAAGCTCCAGCCCGAGTGGTCTCC TCTCAGCTTCTAATTTTGTGCTCTTTCCTGCCCTTTTCCTGGGCCTTCTCAGCTCTCCACCCCCACCACT CTTGACTCAGGTGGTGTCCTTCTTCCTCAAGTCTTGACAATTCCCGGGCCCTTCAGTCCCTGAGCAGTCT ACTTCTGTGTCTGTCACCACATCTTGTCTTTTCCCCTCATTGCATTTATTGCAGTTTATATATATGCTAC TTTTACTTGTTCATTTCTGTCTCCCCTACCAGGCTGTAAATGAGGGCAGAAACCTTGTTTGTTTTATTCA CCATCATGTACCAAGTGCTTGGCACATAGTGGGCCTTCATTAAATGTTTGTTGAATAAAAGAGGGAAGAA GGCAAGCCAACCTTAGCTACAATCCTACCTTTTGATAAAATGTTCCTTTTGACAATATACACGGATTATT ATTTGTACTTTGTTTTTCCATGTGTTTTGCTTTTATCCACTGGCATTTTTAGCTCCTTGAAGACATATCA TGTGTGAGATAACTTCCTTCACATCTCCCATGGTCCCTAGCAAAATGCTAGGCCTGTAGTAGTCAAGGTG CTCAATAAATATTTGTTTGGGTGGTTTGTGAGCCTTGCTGCCAAGTCCTGCCTTTGGGTCGACATAGTAT GGAAGTATTTGAGAGAGAGAACCTTTCCACTCCCACTGCCAGGATTTTGTATTGCCATCGGGTGCCAAAT AAATGCTCATATTTATTACTGA Download Select all
Length	19482
OMIM ID	600639
HGNC ID	HGNC:1503
Unigene ID	Hs.368982
Ensembl ID	ENSG00000106144
PharmGKB ID	PA26086

mRNA Information

mRNA ID	NM_032982.3
Exon	join(1..315,3326..3476,4086..4253,4403..4484,6016..6110, 6383..6559,11709..11837,11990..12080,15570..15719, 16460..16569,16726..19482)
mRNA Sequence	>gi\|320461578\|ref\|NM_032982.3\| Homo sapiens caspase 2, apoptosis-related cysteine peptidase (CASP2), transcript variant 1, mRNA CTTTTGTCTGTCCGCCGAGCACCCCACTTCACCCCATTGGACCGCGCGGCCGCCGCTAGAGCTCTGCGCC TGCGCACGCACCGGGCCGGGGACTGGGTGGCCTGGTGTGTGGGCGCGGCAGGGCGCAGGCGCAGGCGCAG TGTGCGTCCGCGTCTGAGGGGAGGGATGTGGGGGAAGCGACGGCCCCCGGTTTGTTTGGGCTGTGGGCGG TGCGCAGCGGAGAGCCCGGGAAAAGCGGGAAATGGCGGCGCCGAGCGCGGGGTCTTGGTCCACCTTCCAG CACAAGGAGCTGATGGCCGCTGACAGGGGACGCAGGATATTGGGAGTGTGTGGCATGCATCCTCATCATC AGGAAACTCTAAAAAAGAACCGAGTGGTGCTAGCCAAACAGCTGTTGTTGAGCGAATTGTTAGAACATCT TCTGGAGAAGGACATCATCACCTTGGAAATGAGGGAGCTCATCCAGGCCAAAGTGGGCAGTTTCAGCCAG AATGTGGAACTCCTCAACTTGCTGCCTAAGAGGGGTCCCCAAGCTTTTGATGCCTTCTGTGAAGCACTGA GGGAGACCAAGCAAGGCCACCTGGAGGATATGTTGCTCACCACCCTTTCTGGGCTTCAGCATGTACTCCC ACCGTTGAGCTGTGACTACGACTTGAGTCTCCCTTTTCCGGTGTGTGAGTCCTGTCCCCTTTACAAGAAG CTCCGCCTGTCGACAGATACTGTGGAACACTCCCTAGACAATAAAGATGGTCCTGTCTGCCTTCAGGTGA AGCCTTGCACTCCTGAATTTTATCAAACACACTTCCAGCTGGCATATAGGTTGCAGTCTCGGCCTCGTGG CCTAGCACTGGTGTTGAGCAATGTGCACTTCACTGGAGAGAAAGAACTGGAATTTCGCTCTGGAGGGGAT GTGGACCACAGTACTCTAGTCACCCTCTTCAAGCTTTTGGGCTATGACGTCCATGTTCTATGTGACCAGA CTGCACAGGAAATGCAAGAGAAACTGCAGAATTTTGCACAGTTACCTGCACACCGAGTCACGGACTCCTG CATCGTGGCACTCCTCTCGCATGGTGTGGAGGGCGCCATCTATGGTGTGGATGGGAAACTGCTCCAGCTC CAAGAGGTTTTTCAGCTCTTTGACAACGCCAACTGCCCAAGCCTACAGAACAAACCAAAAATGTTCTTCA TCCAGGCCTGCCGTGGAGATGAGACTGATCGTGGGGTTGACCAACAAGATGGAAAGAACCACGCAGGATC CCCTGGGTGCGAGGAGAGTGATGCCGGTAAAGAAAAGTTGCCGAAGATGAGACTGCCCACGCGCTCAGAC ATGATATGCGGCTATGCCTGCCTCAAAGGGACTGCCGCCATGCGGAACACCAAACGAGGTTCCTGGTACA TCGAGGCTCTTGCTCAAGTGTTTTCTGAGCGGGCTTGTGATATGCACGTGGCCGACATGCTGGTTAAGGT GAACGCACTTATCAAGGATCGGGAAGGTTATGCTCCTGGCACAGAATTCCACCGGTGCAAGGAGATGTCT GAATACTGCAGCACTCTGTGCCGCCACCTCTACCTGTTCCCAGGACACCCTCCCACATGATGTCACCTCC CCATCATCCACGCCAAGTGGAAGCCACTGGACCACAGGAGGTGTGATAGAGCCTTTGATCTTCAGGATGC ACGGTTTCTGTTCTGCCCCCTCAGGGATGTGGGAATCTCCCAGACTTGTTTCCTGTGCCCATCATCTCTG CCTTTGAGTGTGGGACTCCAGGCCAGCTCCTTTTCTGTGAAGCCCTTTGCCTGTAGAGCCAGCCTTGGTT GGACCTATTGCCAGGAATGTTTCAGCTGCAGTTGAAGAGCCTGACAAGTGAAGTTGTAAACACAGTGTGG TTATGGGGAGAGGGCATATAAATTCCCCATATTTGTGTTCAGTTCCAGCTTTTGTAGATGGCACTTTAGT GATTGCTTTTATTACATTAGTTAAGATGTCTGAGAGACCATCTCCTATCTTTTATTTCATTCATATCCTC CGCCCTTTTTGTCCTAGAGTGAGAGTTTGGAAGGTGTCCAAATTTAATGTAGACATTATCTTTTGGCTCT GAAGAAGCAAACATGACTAGAGACGCACCTTGCTGCAGTGTCCAGAAGCGGCCTGTGCGTTCCCTTCAGT ACTGCAGCGCCACCCAGTGGAAGGACACTCTTGGCTCGTTTGGGCTCAAGGCACCGCAGCCTGTCAGCCA ACATTGCCTTGCATTTGTACCTTATTGATCTTTGCCCATGGAAGTCTCAAAGATCTTTCGTTGGTTGTTT CTCTGAGCTTTGTTACTGAAATGAGCCTCGTGGGGAGCATCAGAGAAGGCCAGGAAGAATGGTGTGTTTC CCTAGACTCTGTAACCACCTCTCTGTCTTTTTCCTTCCTGAGAAACGTCCATCTCTCTCCCTTACTATTC CCACTTTCATTCAATCAACCTGCACTTCATATCTAGATTTCTAGAAAAGCTTCCTAGCTTATCTCCCTGC TTCATATCTCTCCCTTCTTTACCTTCATTTCATCCTGTTGGCTGCTGCCACCAAATCTGTCTAGAATCCT GCTTTACAGGATCATGTAAATGCTCAAAGATGTAATGTAGTTCTTTGTTCCTGCTTTCTCTTTCAGTATT AAACTCTCCTTTGATATTATGTGGCTTTTATTTCAGTGCCATACATGTTATTGTTTTCAACCTAGAAACC TTTATCCCTGCTTATCTGAAACTTCCCAACTTCCCTGTTCTTTAAGACTTTTTTTTTTTTTTTTTTTTTT TTTGAGACAGAGTCTCGCTCTGTCGCCCAGGCTGGAGGGCAGTGGCACGATCTCAGCTCACTGCAAGCTC CAACTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTTCCAAGTAGCTGGGACTACAGGTGCCCGCCACC GTGCCCGGCTAATTTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTAGCCGGGATGGTCTTGAT CTCCTGACCTCATGATCCACCCACCTCAGCCTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACTGCGCC CGGGCAAGACCTTTTTTTAAAAAAAAAAAAAAAAAAACTTCCATTCTTTCTTCCTCCAGTCTGTTCTCAC ATAACAGAGTAGTTTTGGTTTTTAATTTTTTTTGGTTGTTTGCTGTTTTTTGTTTTTTAAGGTGAGTTCT CACTATGTTTCTCAGACTGGTCTCGAACTCCTGGCCTCAAGCCATCTTCCCGCCTCAGCCTCTCAAATAG CTGGGCTTACAGGCATGAGCCACCACACCTGGCCAGGATTTGGTTGTTTAAATATAAATCTGATCACCCC CCTGCTTAGAACCCTTCTGCTTTCTATTACCCCTCATTTAAAATGTAAACTCTTCACCTTGGTTTATGAG AACTGGTTCTTGCCTTCCCCTTGAACCTCATTAAATGGTGATTTCTTGCTAAGCTCCAGCCCGAGTGGTC TCCTCTCAGCTTCTAATTTTGTGCTCTTTCCTGCCCTTTTCCTGGGCCTTCTCAGCTCTCCACCCCCACC ACTCTTGACTCAGGTGGTGTCCTTCTTCCTCAAGTCTTGACAATTCCCGGGCCCTTCAGTCCCTGAGCAG TCTACTTCTGTGTCTGTCACCACATCTTGTCTTTTCCCCTCATTGCATTTATTGCAGTTTATATATATGC TACTTTTACTTGTTCATTTCTGTCTCCCCTACCAGGCTGTAAATGAGGGCAGAAACCTTGTTTGTTTTAT TCACCATCATGTACCAAGTGCTTGGCACATAGTGGGCCTTCATTAAATGTTTGTTGAATAAAAGAGGGAA GAAGGCAAGCCAACCTTAGCTACAATCCTACCTTTTGATAAAATGTTCCTTTTGACAATATACACGGATT ATTATTTGTACTTTGTTTTTCCATGTGTTTTGCTTTTATCCACTGGCATTTTTAGCTCCTTGAAGACATA TCATGTGTGAGATAACTTCCTTCACATCTCCCATGGTCCCTAGCAAAATGCTAGGCCTGTAGTAGTCAAG GTGCTCAATAAATATTTGTTTGGGTGGTTTGTGAGCCTTGCTGCCAAGTCCTGCCTTTGGGTCGACATAG TATGGAAGTATTTGAGAGAGAGAACCTTTCCACTCCCACTGCCAGGATTTTGTATTGCCATCGGGTGCCA AATAAATGCTCATATTTATTACTGAAAAAAAAAAAAAAAAAA Download Select all
Length	4242

CDS Information

Location	242..1600
CDS Sequence	Download Select all
CCDS ID	CCDS5879.1

Protein Information

Protein ID	NP_116764.2
Protein Name	caspase 2, apoptosis-related cysteine peptidase
Molecular Wt. (Da)	50554
Protein Sequence	>lcl\|NM_032982.3_prot_NP_116764.2_1 [gene=CASP2] [protein=caspase-2 isoform 1 preproprotein] [protein_id=NP_116764.2] [location=242..1600] MAAPSAGSWSTFQHKELMAADRGRRILGVCGMHPHHQETLKKNRVVLAKQLLLSELLEHLLEKDIITLEM RELIQAKVGSFSQNVELLNLLPKRGPQAFDAFCEALRETKQGHLEDMLLTTLSGLQHVLPPLSCDYDLSL PFPVCESCPLYKKLRLSTDTVEHSLDNKDGPVCLQVKPCTPEFYQTHFQLAYRLQSRPRGLALVLSNVHF TGEKELEFRSGGDVDHSTLVTLFKLLGYDVHVLCDQTAQEMQEKLQNFAQLPAHRVTDSCIVALLSHGVE GAIYGVDGKLLQLQEVFQLFDNANCPSLQNKPKMFFIQACRGDETDRGVDQQDGKNHAGSPGCEESDAGK EKLPKMRLPTRSDMICGYACLKGTAAMRNTKRGSWYIEALAQVFSERACDMHVADMLVKVNALIKDREGY APGTEFHRCKEMSEYCSTLCRHLYLFPGHPPT Download Select all
Length	452
Uniprot ID	P10244
Ensembl Protein ID	ENSP00000217026

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
D	Proteolytic Cleavage	169
S	Phosphorylation	157
S	Phosphorylation	126
T	Phosphorylation	158
T	Phosphorylation	127

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
116	ADCYAP1	2369	NP_001108.2	in vitro;in vivo;yeast 2-hybrid	1 197 203 011 350 950
637	BID	3590	NP_932070.1	in vitro;in vivo	11832478
896	CCND3	452	NP_001751.1	in vivo	12011445
1832	DSP	513	NP_004406.2	in vitro	15500642
2802	GOLGA3	3990	NP_005886.2	in vitro;in vivo	10791974
5925	RB1	1574	NP_000312.2	in vitro	15735701
8837	CFLAR	4671	NP_003870.4	in vitro	9228018
51237	-	17815	NP_057543.2	in vitro;in vivo;yeast 2-hybrid	1 135 095 711 972 030

Pathway Information

No matching records could be found.

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd00032	191-446	CASc
cl00042	191-446	CASc superfamily
cd08332	32-118	CARD_CASP2
cl14633	32-118	DD superfamily
smart00115	192-447	CASc
pfam00656	200-445	Peptidase_C14
smart00114	32-120	CARD
cd01671	40-118	CARD
cd08326	36-118	CARD_CASP9
pfam00619	37-118	CARD
cd08327	32-108	CARD_RAIDD
cd08810	37-110	CARD_BCL10

Ontology Information

HPRD ID	1279
Molecular Class	Cysteine protease
Molecular Function	Transcription factor activity (GO:0003700)
Biological Process	Biological_process unknown (GO:0000004)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO

CoReCG

Search results:

General Information

Evidence Information

Gene Details

mRNA Information

CDS Information

Protein Information

Post-translational Modification Information (Source : HPRD)

Enzyme Information

PPi Information

Pathway Information

Structure Information

Domain Information

Ontology Information

SNP Information

Drug Information

External Links

Important Information