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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24085226 | 2013 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 126 Stage : - | - | Up-regulation | - | INHBA expression was significantly higher in CRC tissues when compared to that in the corresponding normal tissues. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | INHBE is a member of the activin beta family (see INHBA; MIM 147290) that plays a role in pancreatic exocrine cell growth and proliferation (Hashimoto et al., 2006 [PubMed 16426570]).[supplied by OMIM, May 2008] |
| Chromosome | 12 |
| Location | 12q13.2 |
| Start | 57849096 |
| End | 57851791 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 2696 |
| OMIM ID | 612031 |
| HGNC ID | HGNC:24029 |
| Unigene ID | Hs.632713 |
| Ensembl ID | - |
| PharmGKB ID | PA134898991 |
Protein Information
| Protein ID | NP_113667.1 |
|---|---|
| Protein Name | inhibin, beta E |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 350 |
| Uniprot ID | Q68G75 |
| Ensembl Protein ID | ENSP00000356117 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 10468 | FST | 641 | NP_037541.1 | in vitro | 12242034 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Cytokine-cytokine receptor interaction | hsa04060 |
| Signaling pathways regulating pluripotency of stem cells | hsa04550 |
| TGF-beta signaling pathway | hsa04350 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| smart00204 | 247-350 | TGFB |
| cl02510 | 247-350 | TGF_beta superfamily |
| pfam00019 | 246-350 | TGF_beta |
| PHA02913 | 246-349 | PHA02913 |
| pfam00688 | 37-222 | TGFb_propeptide |
| cl02928 | 37-222 | TGFb_propeptide superfamily |
Ontology Information
| HPRD ID | 7548 |
|---|---|
| Molecular Class | Growth factor |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.