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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CHD6 | 84181 | chromodomain helicase DNA binding protein 6 | 20 | CHD5; RIGB; CHD-6 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24755471 | 2014 | Cell line : 70 colorectal cancer cell lines Source : - Sample Type : - No. of Sample : - Stage : - | RNA-Seq,whole-exome sequencing and SNP microarray analyses | Mutation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | SANT/Myb domain containing |
| Description | This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013] |
| Chromosome | 20 |
| Location | 20q12 |
| Start | 40030741 |
| End | 40247133 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 216393 |
| OMIM ID | 616114 |
| HGNC ID | HGNC:19057 |
| Unigene ID | Hs.740645 |
| Ensembl ID | ENSG00000124177 |
| PharmGKB ID | PA134974700 |
Protein Information
| Protein ID | NP_115597.3 |
|---|---|
| Protein Name | chromodomain helicase DNA binding protein 6 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 2715 |
| Uniprot ID | Q9C009 |
| Ensembl Protein ID | ENSP00000296839 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 1073;- |
| S | Phosphorylation | 1069;- |
| S | Phosphorylation | 53 |
| S | Phosphorylation | 1714 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 9372 | ZFYVE9 | 4782 | NP_004790.2 | yeast 2-hybrid | 15231748 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00079 | 783-905 | HELICc |
| cl21455 | 783-905 | P-loop_NTPase superfamily |
| cd00046 | 480-629 | DEXDc |
| cl21455 | 480-629 | P-loop_NTPase superfamily |
| cd00024 | 376-427 | CHROMO |
| cl17459 | 376-427 | CHROMO superfamily |
| cd00024 | 294-354 | CHROMO |
| cl17459 | 294-354 | CHROMO superfamily |
| smart00490 | 813-897 | HELICc |
| pfam00271 | 817-897 | Helicase_C |
| pfam00385 | 376-429 | Chromo |
| pfam07533 | 2400-2436 | BRK |
| cl02688 | 2400-2436 | BRK superfamily |
| smart00298 | 376-427 | CHROMO |
| pfam00385 | 293-354 | Chromo |
| smart00592 | 2402-2437 | BRK |
| pfam00270 | 462-629 | DEAD |
| smart00298 | 294-356 | CHROMO |
| pfam00176 | 464-751 | SNF2_N |
| PLN03142 | 460-985 | PLN03142 |
| COG0553 | 359-959 | HepA |
| smart00487 | 454-652 | DEXDc |
| COG1061 | 460-917 | SSL2 |
| COG0553 | 422-888 | HepA |
| COG1203 | 403-690 | Cas3 |
| PHA03247 | 2319-2693 | PHA03247 |
| pfam10243 | 107-316 | MIP-T3 |
| PTZ00449 | 104-373 | PTZ00449 |
| PRK04914 | 592-658 | PRK04914 |
Ontology Information
| HPRD ID | 6972 |
|---|---|
| Molecular Class | Not Available |
| Molecular Function | Ubiquitin-specific protease activity (GO:0004843) |
| Biological Process | Protein metabolism (GO:0019538) |
Drug Information
No matching records could be found.