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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 23324576 | 2013 | Cell line : - Source : - Sample Type : - No. of Sample : 34 fresh tumour samples and 99 DNA CRC samples Stage : - | Microarray, MS-HRM | Hypermethylation and down-regulation | - | TMEM25 is a candidate biomarker methylated and down-regulated in colorectal cancer. epigenetic down-regulation of TMEM25 is cancer-related. TMEM25 hypermethylation might play a significant role in altering expression of this gene in colorectal cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Immunoglobulin superfamily / C2-set domain containing |
| Description | - |
| Chromosome | 11 |
| Location | 11q23.3 |
| Start | 118531088 |
| End | 118546598 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 15511 |
| OMIM ID | 613934 |
| HGNC ID | HGNC:25890 |
| Unigene ID | Hs.564188 |
| Ensembl ID | ENSG00000149582 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_001144037.1 |
|---|---|
| Exon | join(1..147,688..784,1063..1374,1830..2120,2333..2464, 2770..2800,2942..3042,3179..3268,15032..15511) | mRNA Sequence | Download Select all |
| Length | 2419 |
CDS Information
| Location | join(715..784,1063..1374,1830..2120,2333..2464,2770..2800, 2942..3042,3179..3268,15032..15060) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS44745.1 |
Protein Information
| Protein ID | NP_001137506.1 |
|---|---|
| Protein Name | transmembrane protein 25 |
| Molecular Wt. (Da) | 32158 |
| Protein Sequence | Download Select all |
| Length | 322 |
| Uniprot ID | P49257 |
| Ensembl Protein ID | ENSP00000251047 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam08205 | 27-118 | C2-set_2 |
| cl11960 | 27-118 | Ig superfamily |
| pfam07679 | 43-97 | I-set |
Ontology Information
| HPRD ID | 1035 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Structural molecule activity (GO:0005198) |
| Biological Process | Cell growth and/or maintenance (GO:0008151) |
Drug Information
No matching records could be found.