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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| BCAS1 | 8537 | breast carcinoma amplified sequence 1 | 20 | NABC1, AIBC1 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 10857754 | 2000 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | RT-PCR,Northern blotting | Down-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015] |
| Chromosome | 20 |
| Location | 20q13.2 |
| Start | 52560079 |
| End | 52687304 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 127226 |
| OMIM ID | 602968 |
| HGNC ID | HGNC:974 |
| Unigene ID | Hs.400556 |
| Ensembl ID | ENSG00000064787 |
| PharmGKB ID | PA25284 |
mRNA Information
| mRNA ID | ?NM_003657.2 |
|---|---|
| Exon | join(1..333,12043..12119,12612..12681,41794..42374, 74716..74874,75710..75754,85267..85479,95336..95377, 103693..103860,113269..113334,117071..117334, 125770..127226) | mRNA Sequence | Download Select all |
| Length | 3475 |
Protein Information
| Protein ID | NP_003648.2 |
|---|---|
| Protein Name | breast carcinoma amplified sequence 1 |
| Molecular Wt. (Da) | 31982 |
| Protein Sequence | Download Select all |
| Length | 584 |
| Uniprot ID | Q9UQ49 |
| Ensembl Protein ID | ENSP00000294064 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 100 |
| T | Phosphorylation | 482 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 8655 | DYNLL1 | 3334 | NP_003737.1 | yeast 2-hybrid | 11148209 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Ontology Information
| HPRD ID | 5286 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Catalytic activity (GO:0003824) |
| Biological Process | Metabolism (GO:0008152); Energy pathways (GO:0006091) |
Drug Information
No matching records could be found.