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General Information
- Evidence
- Gene
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- Protein
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- Enzyme
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25740697 | 2015 | Cell line : - Source : - Sample Type : Population based case- control study No. of Sample : 88 Stage : - | real time RT-PCR | Polymorhpism | - | The current findings reveal the possibility that piR-015551 may be generated from LNC00964-3, which may be involved in the development of CRC. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008] |
| Chromosome | X |
| Location | Xp22.31 |
| Start | 15402921 |
| End | 15511711 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 108791 |
| OMIM ID | 300931 |
| HGNC ID | HGNC:30048 |
| Unigene ID | Hs.495728 |
| Ensembl ID | ENSG00000087842 |
| PharmGKB ID | PA134870022 |
mRNA Information
| mRNA ID | ?NM_001018109.2 |
|---|---|
| Exon | join(1..399,2280..2427,13768..13860,33849..33932, 37535..37741,67599..67683,86039..86083,96058..96140, 103338..103404,108473..108790) | mRNA Sequence | Download Select all |
| Length | 1542 |
Protein Information
| Protein ID | NP_001018119.1 |
|---|---|
| Protein Name | pirin (iron-binding nuclear protein) |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 290 |
| Uniprot ID | Q9Y233 |
| Ensembl Protein ID | ENSP00000355847 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| T | Phosphorylation | 8 |
| T | Phosphorylation | 8 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 4093 | SMAD9 | 4484 | BAA21128.1 | yeast 2-hybrid | 15231748 |
| 4784 | NFIX | 1234 | NP_002492.2 | in vivo;yeast 2-hybrid | 9079676 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam05726 | 171-277 | Pirin_C |
| cl23549 | 171-277 | Pirin_C superfamily |
| pfam02678 | 21-118 | Pirin |
| cl21464 | 21-118 | cupin_like superfamily |
| COG1741 | 17-275 | YhaK |
| TIGR02451 | 19-101 | anti_sig_ChrR |
Ontology Information
| HPRD ID | 16070 |
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.