Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CASK | 8573 | calcium/calmodulin-dependent serine protein kinase (MAGUK family)  | X | LIN2, CAGH39, FGS4  |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24927672    | 2014 | Cell line : - Source : Department ofGasterointestinal surgery hospital of First affiliated hospital of Chongqing medical university and Chongqing Three Georges central hospital. Sample Type : CRC tumor No. of Sample : 156 Stage : - | Immunohistochemistry and Western blotting | Up-regulation | - | CASK is an independent prognostic factor for CRC, which suggests that it is a novel and crucial predictor for CRC metastasis. |
Gene Details

| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This gene encodes a calcium/calmodulin-dependent serine protein kinase. The encoded protein is a MAGUK (membrane-associated guanylate kinase) protein family member. These proteins are scaffold proteins and the encoded protein is located at synapses in the brain. Mutations in this gene are associated with FG syndrome 4, mental retardation and microcephaly with pontine and cerebellar hypoplasia, and a form of X-linked mental retardation. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]   |
| Chromosome | X |
| Location | Xp11.4 |
| Start | 41374187   |
| End | 41782415   |
| Strand | -   |
| Gene Sequence |    Download   Select all |
| Length | 408229   |
| OMIM ID | 300172    |
| HGNC ID | HGNC:1497    |
| Unigene ID | Hs.495984    |
| Ensembl ID | ENSG00000147044    |
| PharmGKB ID | PA26081    |
mRNA Information
| mRNA ID | ?NM_001126054.2 |
|---|---|
| Exon | join(1..149,69852..69964,135796..135901,177478..177555, 183623..183695,251549..251651,257627..257802, 262518..262640,286418..286501,296376..296475, 313054..313175,333487..333564,336092..336172, 344551..344739,353333..353411,361435..361520, 363232..363300,369164..369360,380273..380388, 388106..388186,388293..388373,391870..392072, 399045..399128,402483..408145)   | mRNA Sequence |    Download   Select all |
| Length | 8234   |
CDS Information
| Location | 91..2748 |
|---|---|
| CDS Sequence |    Download   Select all |
| CCDS ID | CCDS14257.1 |    
Protein Information
| Protein ID | NP_001119526.1 |
|---|---|
| Protein Name | calcium/calmodulin-dependent serine protein kinase (MAGUK family) |
| Molecular Wt. (Da) | 75001 |
| Protein Sequence |    Download   Select all |
| Length | 926   |
| Uniprot ID | Q9Y251 |    
| Ensembl Protein ID | ENSP00000308107   |    
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| T | Phosphorylation | 49 |
| S | Phosphorylation | 51 |
| S | Phosphorylation | 394 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING)      View   
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 493 |    ATP2B4 |    159 |    NP_001675.3 |    in vitro;in vivo |    12511555    |
| 2035 |    EPB41 |    558 |    AAD42222.1 |    in vitro |    9660868    |
| 2059 |    EPS8 |    2563 |    NP_004438.3 |    in vitro;in vivo |    16688213    |
| 2898 |    GRIK2 |    692 |    NP_068775.1 |    in vitro;in vivo |    12151522    |
| 5864 |    RAB3A |    1535 |    NP_002857.1 |    in vitro;in vivo;yeast 2-hybrid |    11377421    |
| 6382 |    SDC1 |    1718 |    NP_002988.3 |    in vitro;yeast 2-hybrid |    9660868    |
| 6383 |    SDC2 |    803 |    NP_002989.2 |    in vitro;yeast 2-hybrid |    9660868    |
| 9672 |    SDC3 |    1719 |    NP_055469.3 |    in vitro;in vivo |    10460248    |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Tight junction |    hsa04530 |    
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd14094 | 8-307  | STKc_CASK |
| cl21453 | 8-307  | PKc_like superfamily |
| cd12081 | 616-677  | SH3_CASK |
| cl17036 | 616-677  | SH3 superfamily |
| cd00071 | 742-907  | GMPK |
| cl17190 | 742-907  | NK superfamily |
| cd00992 | 488-568  | PDZ_signaling |
| cl00117 | 488-568  | PDZ superfamily |
| cd05117 | 11-275  | STKc_CAMK |
| cd14086 | 10-307  | STKc_CaMKII |
| cd14003 | 12-275  | STKc_AMPK-like |
| cd14093 | 8-276  | STKc_PhKG |
| cd14091 | 12-310  | STKc_RSK_C |
| cd14083 | 9-275  | STKc_CaMKI |
| cd14084 | 8-276  | STKc_Chk2 |
| cd14085 | 8-313  | STKc_CaMKIV |
| cd14095 | 12-275  | STKc_DCKL |
| cd14006 | 18-275  | STKc_MLCK-like |
| cd14081 | 11-276  | STKc_BRSK1_2 |
| cd08215 | 12-274  | STKc_Nek |
| cd14008 | 18-276  | STKc_LKB1_CaMKK |
| cd14166 | 10-303  | STKc_CaMKI_gamma |
| cd14105 | 9-276  | STKc_DAPK |
| cd14090 | 10-275  | STKc_Mnk |
| cd14181 | 8-276  | STKc_PhKG2 |
| cd14089 | 16-275  | STKc_MAPKAPK |
| cd14103 | 18-276  | STKc_MLCK |
| cd06606 | 16-276  | STKc_MAPKKK |
| cd14663 | 12-275  | STKc_SnRK3 |
| cd14167 | 10-276  | STKc_CaMKI_alpha |
| cd14007 | 12-277  | STKc_Aurora |
| smart00072 | 748-914  | GuKc |
| cd14009 | 18-275  | STKc_ATG1_ULK_like |
| cd14114 | 10-276  | STKc_Twitchin_like |
| cd14185 | 12-275  | STKc_DCKL3 |
| cd14098 | 12-275  | STKc_Rad53_Cds1 |
| cd14092 | 8-281  | STKc_MSK_C |
| cd14069 | 12-276  | STKc_Chk1 |
| cd14194 | 9-276  | STKc_DAPK1 |
| cd14196 | 9-276  | STKc_DAPK2 |
| cd00180 | 18-274  | PKc |
| cd14195 | 9-277  | STKc_DAPK3 |
| cd14175 | 10-314  | STKc_RSK1_C |
| cd14014 | 12-271  | STKc_PknB_like |
| cd14079 | 12-276  | STKc_AMPK_alpha |
| cd14184 | 10-275  | STKc_DCKL2 |
| cd14096 | 12-276  | STKc_RCK1-like |
| cd14087 | 12-276  | STKc_PSKH1 |
| cd14182 | 8-278  | STKc_PhKG1 |
| cd14106 | 8-276  | STKc_DRAK |
| cd14169 | 11-276  | STKc_CaMKI_beta |
| cd14176 | 8-350  | STKc_RSK2_C |
| cd14177 | 8-314  | STKc_RSK4_C |
| cd05123 | 18-275  | STKc_AGC |
| cd14178 | 8-280  | STKc_RSK3_C |
| cd06614 | 11-277  | STKc_PAK |
| cd05122 | 11-276  | PKc_STE |
| cd14168 | 9-307  | STKc_CaMKI_delta |
| cd14173 | 10-276  | STKc_Mnk2 |
| cd14074 | 12-276  | STKc_SNRK |
| cd05581 | 12-275  | STKc_PDK1 |
| cd14172 | 10-276  | STKc_MAPKAPK3 |
| cd14174 | 10-277  | STKc_Mnk1 |
| cd05118 | 12-276  | STKc_CMGC |
| cd14080 | 12-276  | STKc_TSSK-like |
| cd14183 | 10-278  | STKc_DCKL1 |
| cd14088 | 10-276  | STKc_CaMK_like |
| cd05579 | 18-280  | STKc_MAST_like |
| cd07829 | 12-276  | STKc_CDK_like |
| cd14171 | 18-276  | STKc_MAPKAPK5 |
| cd14099 | 12-276  | STKc_PLK |
| cd14077 | 12-276  | STKc_Kin1_2 |
| cd06627 | 11-276  | STKc_Cdc7_like |
| cd14097 | 11-276  | STKc_STK33 |
| cd14082 | 16-275  | STKc_PKD |
| cd14071 | 12-276  | STKc_SIK |
| cd14104 | 11-278  | STKc_Titin |
| cd14180 | 8-277  | STKc_MSK2_C |
| cd14073 | 12-276  | STKc_NUAK |
| cd14119 | 18-276  | STKc_LKB1 |
| cd14078 | 9-276  | STKc_MELK |
| cd14072 | 12-276  | STKc_MARK |
| cd14170 | 16-278  | STKc_MAPKAPK2 |
| cd06623 | 17-280  | PKc_MAPKK_plant_like |
| cd07833 | 12-276  | STKc_CDKL |
| cd14002 | 10-276  | STKc_STK36 |
| cd08217 | 12-274  | STKc_Nek2 |
| cd05578 | 12-276  | STKc_Yank1 |
| cd14179 | 16-278  | STKc_MSK1_C |
| cd14075 | 12-276  | STKc_NIM1 |
| cd05580 | 12-280  | STKc_PKA_like |
| cd06609 | 12-298  | STKc_MST3_like |
| cd14109 | 8-276  | PK_Unc-89_rpt1 |
| cd14191 | 9-276  | STKc_MLCK1 |
| cd14197 | 7-276  | STKc_DRAK1 |
| cd06632 | 16-276  | STKc_MEKK1_plant |
| cd14111 | 12-276  | STKc_SPEG_rpt2 |
| cd14118 | 18-275  | STKc_CAMKK |
| cd05572 | 18-275  | STKc_cGK |
| cd14198 | 18-276  | STKc_DRAK2 |
| cd08530 | 12-274  | STKc_CNK2-like |
| cd14121 | 16-275  | STKc_ULK3 |
| cd08224 | 12-272  | STKc_Nek6_7 |
| cd14193 | 16-276  | STKc_MLCK4 |
| cd07841 | 12-279  | STKc_CDK7 |
| cd14161 | 12-276  | STKc_NUAK2 |
| cd08529 | 12-276  | STKc_FA2-like |
| cd06625 | 17-275  | STKc_MEKK3_like |
| cd06612 | 9-276  | STKc_MST1_2 |
| cd14113 | 5-276  | STKc_Trio_C |
| cd14107 | 11-276  | STKc_obscurin_rpt1 |
| cd14186 | 9-276  | STKc_PLK4 |
| cd14115 | 18-275  | STKc_Kalirin_C |
| cd13994 | 18-276  | STKc_HAL4_like |
| cd14192 | 12-276  | STKc_MLCK3 |
| cd13999 | 18-264  | STKc_MAP3K-like |
| cd12035 | 616-677  | SH3_MPP1-like |
| cd14165 | 12-276  | STKc_TSSK1_2-like |
| cd14070 | 12-276  | STKc_HUNK |
| cd05584 | 17-265  | STKc_p70S6K |
| cd06611 | 9-290  | STKc_SLK_like |
| cd06648 | 18-277  | STKc_PAK_II |
| cd06610 | 10-274  | STKc_OSR1_SPAK |
| cd14665 | 12-275  | STKc_SnRK2-3 |
| cd07840 | 12-275  | STKc_CDK9_like |
| cd07830 | 12-276  | STKc_MAK_like |
| cd14005 | 12-276  | STKc_PIM |
| cd14662 | 12-275  | STKc_SnRK2 |
| cd14162 | 12-276  | STKc_TSSK4-like |
| cd05573 | 12-277  | STKc_ROCK_NDR_like |
| cd07832 | 12-276  | STKc_CCRK |
| cd08219 | 12-264  | STKc_Nek3 |
| cd05612 | 10-280  | STKc_PRKX_like |
| cd08225 | 12-276  | STKc_Nek5 |
| cd08218 | 12-276  | STKc_Nek1 |
| cd07834 | 12-278  | STKc_MAPK |
| cd05611 | 18-277  | STKc_Rim15_like |
| cd14190 | 16-276  | STKc_MLCK2 |
| cd07846 | 12-275  | STKc_CDKL2_3 |
| cd05570 | 17-280  | STKc_PKC |
| cd06624 | 12-276  | STKc_ASK |
| cd14200 | 12-276  | STKc_CaMKK1 |
| cd05571 | 16-275  | STKc_PKB |
| cd06631 | 16-276  | STKc_YSK4 |
| cd06621 | 18-277  | PKc_Pek1_like |
| cd14199 | 12-276  | STKc_CaMKK2 |
| cd12080 | 616-677  | SH3_MPP1 |
| cd14108 | 10-276  | STKc_SPEG_rpt1 |
| cd14209 | 10-280  | STKc_PKA |
| cd06630 | 16-274  | STKc_MEKK1 |
| cd07838 | 12-276  | STKc_CDK4_6_like |
| cd06626 | 18-276  | STKc_MEKK4 |
| cd14164 | 12-276  | STKc_TSSK6-like |
| cd05630 | 17-278  | STKc_GRK6 |
| cd06628 | 17-276  | STKc_Byr2_like |
| cd13996 | 8-272  | STKc_EIF2AK |
| cd06659 | 18-301  | STKc_PAK6 |
| cd14004 | 12-276  | STKc_PASK |
| cd05631 | 17-265  | STKc_GRK4 |
| cd06917 | 11-277  | STKc_NAK1_like |
| cd05609 | 12-280  | STKc_MAST |
| cd07852 | 12-278  | STKc_MAPK15-like |
| cd08223 | 12-276  | STKc_Nek4 |
| cd07847 | 10-275  | STKc_CDKL1_4 |
| cd14131 | 12-276  | PKc_Mps1 |
| cd05632 | 9-277  | STKc_GRK5 |
| cd05577 | 18-265  | STKc_GRK |
| cd14076 | 12-276  | STKc_Kin4 |
| cd14116 | 10-276  | STKc_Aurora-A |
| cd05595 | 16-265  | STKc_PKB_beta |
| cd05605 | 17-277  | STKc_GRK4_like |
| cd07835 | 12-276  | STKc_CDK1_CdkB_like |
| cd14187 | 18-272  | STKc_PLK1 |
| cd14163 | 12-276  | STKc_TSSK3-like |
| cd06613 | 11-274  | STKc_MAP4K3_like |
| cd07864 | 10-276  | STKc_CDK12 |
| cd05575 | 17-265  | STKc_SGK |
| cd07848 | 12-274  | STKc_CDKL5 |
| cd08220 | 12-274  | STKc_Nek8 |
| cd08221 | 58-276  | STKc_Nek9 |
| cd05590 | 16-280  | STKc_nPKC_eta |
| TIGR03263 | 742-910  | guanyl_kin |
| cd07861 | 12-276  | STKc_CDK1_euk |
| cd14010 | 12-275  | STKc_ULK4 |
| cd07836 | 12-275  | STKc_Pho85 |
| cd05599 | 12-280  | STKc_NDR_like |
| cd13990 | 12-275  | STKc_TLK |
| cd07860 | 12-275  | STKc_CDK2_3 |
| cd14120 | 18-274  | STKc_ULK1_2-like |
| cd14202 | 16-276  | STKc_ULK1 |
| cd06605 | 17-281  | PKc_MAPKK |
| cd11862 | 616-676  | SH3_MPP |
| cd13987 | 18-275  | STKc_SBK1 |
| cd05607 | 12-274  | STKc_GRK7 |
| cd08222 | 12-276  | STKc_Nek11 |
| cd06647 | 12-277  | STKc_PAK_I |
| cd05596 | 12-257  | STKc_ROCK |
| cd14133 | 12-276  | PKc_DYRK_like |
| cd06639 | 10-277  | STKc_myosinIIIB_N |
| cd05608 | 17-265  | STKc_GRK1 |
| cd06643 | 9-276  | STKc_SLK |
| cd05582 | 17-265  | STKc_RSK_N |
| cd06655 | 12-277  | STKc_PAK2 |
| cd08528 | 12-270  | STKc_Nek10 |
| cd07866 | 12-275  | STKc_BUR1 |
| cd13993 | 12-272  | STKc_Pat1_like |
| cd06658 | 18-277  | STKc_PAK5 |
| cd06644 | 10-278  | STKc_STK10 |
| cd05592 | 17-280  | STKc_nPKC_theta_like |
| cd06608 | 10-276  | STKc_myosinIII_N_like |
| cd08228 | 18-264  | STKc_Nek6 |
| cd07843 | 10-275  | STKc_CDC2L1 |
| cd14110 | 9-276  | STKc_obscurin_rpt2 |
| cd14019 | 10-276  | STKc_Cdc7 |
| cd07865 | 12-275  | STKc_CDK9 |
| cd07851 | 10-278  | STKc_p38 |
| cd14137 | 12-278  | STKc_GSK3 |
| cd05622 | 10-292  | STKc_ROCK1 |
| cd05593 | 12-265  | STKc_PKB_gamma |
| cd06651 | 16-275  | STKc_MEKK3 |
| cd05594 | 12-265  | STKc_PKB_alpha |
| cd13979 | 16-271  | STKc_Mos |
| cd05614 | 12-280  | STKc_MSK2_N |
| cd14112 | 9-276  | STKc_Unc-89_rpt2 |
| cd14117 | 10-281  | STKc_Aurora-B_like |
| cd06642 | 9-298  | STKc_STK25 |
| cd06622 | 10-277  | PKc_PBS2_like |
| cd06657 | 18-276  | STKc_PAK4 |
| cd05583 | 17-277  | STKc_MSK_N |
| cd06629 | 16-276  | STKc_Bck1_like |
| cd05603 | 16-265  | STKc_SGK2 |
| cd13997 | 18-274  | PKc_Wee1_like |
| cd06638 | 10-276  | STKc_myosinIIIA_N |
| cd05621 | 9-277  | STKc_ROCK2 |
| cd06656 | 12-277  | STKc_PAK3 |
| cd06652 | 12-273  | STKc_MEKK2 |
| cd05574 | 12-277  | STKc_phototropin_like |
| cd05604 | 16-276  | STKc_SGK3 |
| cd05613 | 12-265  | STKc_MSK1_N |
| cd05602 | 12-265  | STKc_SGK1 |
| cd14210 | 12-276  | PKc_DYRK |
| cd14201 | 12-277  | STKc_ULK2 |
| cd07845 | 12-278  | STKc_CDK10 |
| cd14132 | 9-274  | STKc_CK2_alpha |
| cd06654 | 12-277  | STKc_PAK1 |
| cd14188 | 16-273  | STKc_PLK2 |
| cd05597 | 10-280  | STKc_DMPK_like |
| cd07839 | 12-275  | STKc_CDK5 |
| cd06641 | 9-298  | STKc_MST3 |
| cd05589 | 12-265  | STKc_PKN |
| cd05601 | 12-280  | STKc_CRIK |
| cd05587 | 17-265  | STKc_cPKC |
| cd06653 | 12-275  | STKc_MEKK3_like_u1 |
| cd14046 | 12-273  | STKc_EIF2AK4_GCN2_rpt2 |
| cd07831 | 12-275  | STKc_MOK |
| cd05616 | 12-265  | STKc_cPKC_beta |
| cd07858 | 18-276  | STKc_TEY_MAPK |
| cd06640 | 9-298  | STKc_MST4 |
| cd07837 | 10-275  | STKc_CdkB_plant |
| cd07855 | 8-279  | STKc_ERK5 |
| cd14134 | 7-276  | PKc_CLK |
| cd05620 | 16-277  | STKc_nPKC_delta |
| PRK00300 | 742-907  | gmk |
| cd05623 | 7-257  | STKc_MRCK_alpha |
| cd13983 | 16-276  | STKc_WNK |
| cd05619 | 6-280  | STKc_nPKC_theta |
| cd05624 | 7-257  | STKc_MRCK_beta |
| cd07842 | 12-275  | STKc_CDK8_like |
| cd13989 | 18-219  | STKc_IKK |
| cd13976 | 24-276  | PK_TRB |
| cd14189 | 17-273  | STKc_PLK3 |
| cd13982 | 71-274  | STKc_IRE1 |
| COG0194 | 738-911  | Gmk |
| cd00192 | 16-266  | PTKc |
| cd07849 | 12-278  | STKc_ERK1_2_like |
| cd12033 | 616-674  | SH3_MPP7 |
| cd14065 | 18-209  | PKc_LIMK_like |
| cd14101 | 12-277  | STKc_PIM2 |
| cd05585 | 17-280  | STKc_YPK1_like |
| cd07859 | 12-277  | STKc_TDY_MAPK |
| cd07863 | 12-276  | STKc_CDK4 |
| cd14012 | 48-274  | PK_eIF2AK_GCN2_rpt1 |
| cd14022 | 26-276  | PK_TRB2 |
| cd05586 | 18-280  | STKc_Sck1_like |
| cd05618 | 12-265  | STKc_aPKC_iota |
| cd13991 | 12-219  | STKc_NIK |
| cd05615 | 4-265  | STKc_cPKC_alpha |
| cd14135 | 12-276  | STKc_PRP4 |
| cd12037 | 616-674  | SH3_MPP2 |
| cd14066 | 18-271  | STKc_IRAK |
| cd05617 | 12-265  | STKc_aPKC_zeta |
| cd05598 | 10-290  | STKc_LATS |
| cd14050 | 11-274  | PKc_Myt1 |
| cd07870 | 16-276  | STKc_PFTAIRE2 |
| cd14048 | 12-273  | STKc_EIF2AK3_PERK |
| cd05591 | 16-280  | STKc_nPKC_epsilon |
| cd08229 | 18-264  | STKc_Nek7 |
| cd06637 | 11-297  | STKc_TNIK |
| cd14052 | 12-274  | PTKc_Wee1_fungi |
| cd14226 | 7-277  | PKc_DYRK1 |
| cd05610 | 18-274  | STKc_MASTL |
| cd06636 | 11-276  | STKc_MAP4K4_6_N |
| cd14047 | 8-264  | STKc_EIF2AK2_PKR |
| cd14145 | 14-221  | STKc_MLK1 |
| cd14061 | 17-221  | STKc_MLK |
| cd07857 | 12-278  | STKc_MPK1 |
| cd05629 | 12-277  | STKc_NDR_like_fungal |
| cd14038 | 18-219  | STKc_IKK_beta |
| cd14225 | 12-276  | PKc_DYRK4 |
| cd14000 | 17-274  | STKc_LRRK |
| cd07844 | 12-276  | STKc_PCTAIRE_like |
| cd14023 | 67-276  | PK_TRB1 |
| cd06620 | 18-281  | PKc_Byr1_like |
| cd14024 | 28-276  | PK_TRB3 |
| cd07869 | 10-278  | STKc_PFTAIRE1 |
| cd05627 | 10-280  | STKc_NDR2 |
| cd13974 | 125-273  | STKc_SHIK |
| cd14100 | 74-276  | STKc_PIM1 |
| cd06615 | 9-280  | PKc_MEK |
| cd07862 | 12-275  | STKc_CDK6 |
| cd07880 | 10-299  | STKc_p38gamma |
| cd14212 | 12-276  | PKc_YAK1 |
| cd05606 | 17-280  | STKc_beta_ARK |
| cd06633 | 3-281  | STKc_TAO3 |
| cd14146 | 17-221  | STKc_MLK4 |
| cd14102 | 11-276  | STKc_PIM3 |
| cd07871 | 18-276  | STKc_PCTAIRE3 |
| cd13985 | 17-272  | STKc_GAK_like |
| cd14148 | 17-219  | STKc_MLK2 |
| cd07850 | 12-283  | STKc_JNK |
| cd05588 | 17-265  | STKc_aPKC |
| cd06607 | 7-276  | STKc_TAO |
| cd14214 | 8-276  | PKc_CLK3 |
| cd07876 | 12-276  | STKc_JNK2 |
| cd06645 | 9-278  | STKc_MAP4K3 |
| cd13978 | 18-274  | STKc_RIP |
| cd05628 | 12-255  | STKc_NDR1 |
| cd14155 | 18-209  | PKc_TESK |
| cd07877 | 10-278  | STKc_p38alpha |
| cd07856 | 18-276  | STKc_Sty1_Hog1 |
| cd14040 | 12-276  | STKc_TLK1 |
| cd05049 | 14-267  | PTKc_Trk |
| cd13986 | 12-273  | STKc_16 |
| cd14147 | 14-221  | STKc_MLK3 |
| cd14058 | 18-256  | STKc_TAK1 |
| cd06616 | 15-277  | PKc_MKK4 |
| cd12036 | 616-676  | SH3_MPP5 |
| cd14031 | 18-278  | STKc_WNK3 |
| cd06650 | 1-280  | PKc_MEK1 |
| cd07872 | 10-292  | STKc_PCTAIRE2 |
| cd07854 | 8-277  | STKc_MAPK4_6 |
| cd14136 | 7-276  | STKc_SRPK |
| cd06646 | 12-207  | STKc_MAP4K5 |
| cd14156 | 18-209  | PKc_LIMK_like_unk |
| cd06619 | 9-280  | PKc_MKK5 |
| cd07873 | 10-278  | STKc_PCTAIRE1 |
| cd12039 | 616-674  | SH3_MPP3 |
| cd14041 | 8-276  | STKc_TLK2 |
| cd14049 | 18-271  | STKc_EIF2AK1_HRI |
| PRK14737 | 740-917  | gmk |
| cd05600 | 18-280  | STKc_Sid2p_like |
| cd07878 | 18-278  | STKc_p38beta |
| cd14059 | 35-219  | STKc_MAP3K12_13 |
| cd14224 | 12-276  | PKc_DYRK2_3 |
| cd13977 | 12-269  | STKc_PDIK1L |
| cd07853 | 18-282  | STKc_NLK |
| pfam00595 | 490-567  | PDZ |
| cd12038 | 616-674  | SH3_MPP6 |
| cd06634 | 3-305  | STKc_TAO2 |
| cd14221 | 18-209  | STKc_LIMK1 |
| cd13988 | 18-237  | STKc_TBK1 |
| cd07879 | 18-280  | STKc_p38delta |
| cd14037 | 16-273  | STKc_NAK_like |
| cd05633 | 12-265  | STKc_GRK3 |
| cd05112 | 18-290  | PTKc_Itk |
| cd14223 | 12-265  | STKc_GRK2 |
| cd14068 | 17-272  | STKc_LRRK2 |
| cd14215 | 8-276  | PKc_CLK2 |
| cd06649 | 1-230  | PKc_MEK2 |
| cd07874 | 61-276  | STKc_JNK3 |
| cd14039 | 18-219  | STKc_IKK_alpha |
| cd12034 | 616-674  | SH3_MPP4 |
| cd06635 | 3-292  | STKc_TAO1 |
| cd05040 | 16-209  | PTKc_Ack_like |
| cd07875 | 61-276  | STKc_JNK1 |
| cd14033 | 18-273  | STKc_WNK4 |
| cd06617 | 9-278  | PKc_MKK3_6 |
| cd05056 | 9-269  | PTKc_FAK |
| cd06618 | 18-280  | PKc_MKK7 |
| cd14051 | 16-274  | PTKc_Wee1 |
| cd14150 | 18-258  | STKc_A-Raf |
| cd14154 | 18-209  | STKc_LIMK |
| cd14139 | 16-274  | PTKc_Wee1b |
| cd14036 | 17-272  | STKc_GAK |
| cd14032 | 18-278  | STKc_WNK2_like |
| cd14030 | 18-278  | STKc_WNK1 |
| cd05039 | 13-274  | PTKc_Csk_like |
| cd14213 | 12-276  | PKc_CLK1_4 |
| pfam02828 | 405-454  | L27 |
| cl02672 | 405-454  | L27 superfamily |
| cd14138 | 10-274  | PTKc_Wee1a |
| smart00228 | 487-569  | PDZ |
| cd14158 | 18-219  | STKc_IRAK4 |
| cd11861 | 616-674  | SH3_DLG-like |
| cd13968 | 18-161  | PKc_like |
| cd14016 | 12-166  | STKc_CK1 |
| cd14067 | 32-221  | STKc_LRRK1 |
| cd14062 | 18-225  | STKc_Raf |
| cd13995 | 18-276  | STKc_MAP3K8 |
| cd05038 | 18-220  | PTKc_Jak_rpt2 |
| cd05089 | 4-264  | PTKc_Tie1 |
| cd05032 | 18-266  | PTKc_InsR_like |
| cd05148 | 12-237  | PTKc_Srm_Brk |
| cd05082 | 13-273  | PTKc_Csk |
| pfam02828 | 346-397  | L27 |
| cl02672 | 346-397  | L27 superfamily |
| cd05059 | 18-247  | PTKc_Tec_like |
| cd14011 | 56-276  | PK_SCY1_like |
| cd14222 | 18-227  | STKc_LIMK2 |
| smart00569 | 407-455  | L27 |
| cd05055 | 13-266  | PTKc_PDGFR |
| cd14017 | 12-247  | STKc_TTBK |
| cd00136 | 500-568  | PDZ |
| cd05048 | 13-221  | PTKc_Ror |
| cd05085 | 16-264  | PTKc_Fer |
| cd05074 | 4-239  | PTKc_Tyro3 |
| cd14063 | 13-266  | PK_KSR |
| cd05092 | 57-240  | PTKc_TrkA |
| cd05047 | 16-264  | PTKc_Tie |
| cd05079 | 18-266  | PTKc_Jak1_rpt2 |
| cd05052 | 54-273  | PTKc_Abl |
| cd05057 | 17-221  | PTKc_EGFR_like |
| cd05072 | 45-240  | PTKc_Lyn |
| cd14151 | 3-225  | STKc_B-Raf |
| smart00326 | 616-674  | SH3 |
| cd14001 | 57-214  | PKc_TOPK |
| pfam07653 | 616-679  | SH3_2 |
| cd14149 | 18-225  | STKc_C-Raf |
| cd05626 | 16-219  | STKc_LATS2 |
| cd05625 | 59-280  | STKc_LATS1 |
| cd05034 | 41-273  | PTKc_Src_like |
| cd14060 | 19-271  | STKc_MLTK |
| cd14027 | 57-233  | STKc_RIP1 |
| cd05097 | 16-216  | PTKc_DDR_like |
| cd05080 | 16-238  | PTKc_Tyk2_rpt2 |
| cd00174 | 616-674  | SH3 |
| smart00569 | 348-401  | L27 |
| cd08216 | 13-219  | PK_STRAD |
| cd05060 | 18-223  | PTKc_Syk_like |
| cd05115 | 4-223  | PTKc_Zap-70 |
| cd05041 | 16-272  | PTKc_Fes_like |
| PRK14738 | 742-904  | gmk |
| cd05093 | 18-240  | PTKc_TrkB |
| cd13998 | 16-220  | STKc_TGFbR-like |
| cd14203 | 45-266  | PTKc_Src_Fyn_like |
| cd05045 | 14-264  | PTKc_RET |
| cd14205 | 16-214  | PTKc_Jak2_rpt2 |
| cd14053 | 16-216  | STKc_ACVR2 |
| cd05096 | 8-216  | PTKc_DDR1 |
| cd05099 | 18-244  | PTKc_FGFR4 |
| cd12029 | 613-679  | SH3_DLG3 |
| cd12031 | 613-674  | SH3_DLG1 |
| cd05114 | 18-219  | PTKc_Tec_Rlk |
| cd05081 | 17-216  | PTKc_Jak3_rpt2 |
| cd13975 | 125-264  | PKc_Dusty |
| cd05033 | 16-214  | PTKc_EphR |
| cd12032 | 613-674  | SH3_DLG2 |
| cd14018 | 124-272  | STKc_PINK1 |
| cd05101 | 58-238  | PTKc_FGFR2 |
| cd05036 | 14-247  | PTKc_ALK_LTK |
| cd05069 | 45-266  | PTKc_Yes |
| cd14013 | 122-276  | STKc_SNT7_plant |
| cd05094 | 18-240  | PTKc_TrkC |
| cd05091 | 57-221  | PTKc_Ror2 |
| cd05090 | 33-221  | PTKc_Ror1 |
| cd05065 | 16-239  | PTKc_EphR_B |
| cd05063 | 16-220  | PTKc_EphR_A2 |
| cd05100 | 58-244  | PTKc_FGFR3 |
| cd14055 | 16-216  | STKc_TGFbR2_like |
| cd05050 | 18-273  | PTKc_Musk |
| cd14216 | 7-276  | STKc_SRPK1 |
| cd11949 | 616-674  | SH3_GRB2_C |
| cd05073 | 41-266  | PTKc_Hck |
| smart00220 | 12-276  | S_TKc |
| pfam00625 | 738-911  | Guanylate_kin |
| pfam00069 | 12-276  | Pkinase |
| COG0515 | 12-280  | SPS1 |
| PTZ00263 | 12-294  | PTZ00263 |
| smart00221 | 13-264  | STYKc |
| PLN00009 | 10-278  | PLN00009 |
| PTZ00283 | 12-277  | PTZ00283 |
| smart00219 | 13-264  | TyrKc |
| PTZ00267 | 9-277  | PTZ00267 |
| pfam07714 | 13-266  | Pkinase_Tyr |
| PTZ00024 | 18-277  | PTZ00024 |
| PLN00034 | 18-281  | PLN00034 |
| TIGR03903 | 33-296  | TOMM_kin_cyc |
| PHA03390 | 8-277  | pk1 |
| PTZ00266 | 12-277  | PTZ00266 |
| PLN02772 | 740-917  | PLN02772 |
| PTZ00426 | 62-280  | PTZ00426 |
| PHA03212 | 62-215  | PHA03212 |
| PHA03207 | 58-223  | PHA03207 |
| PHA03209 | 62-214  | PHA03209 |
| PHA03211 | 62-210  | PHA03211 |
| PTZ00036 | 12-295  | PTZ00036 |
| PRK13184 | 12-289  | pknD |
| PHA03210 | 45-214  | PHA03210 |
Ontology Information
| HPRD ID | 4166 |    
|---|---|
| Molecular Class | Serine/threonine kinase |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Signal transduction (GO:0007165); Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)   |
Drug Information
No matching records could be found.
External Links
| ArrayExpress | GO |    
|---|---|
| ICGC | GO |    
| Cancer3D | GO |    
| COSMIC | GO |    
| NCG | GO |    
| TSGene | GO |    
| Tumor Gene Family of Databases | GO |    
| CCDB | GO |    
| G2SBC | GO |    
| Osteosarcoma Database | GO |    
| RCDB | GO |    
