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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
CD164 8763 CD164 molecule, sialomucin  6MUC-24, MGC-24 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
22409183   2012Cell line : HCT116

Source : -

Sample Type : CRC tumor and normal tissues

No. of Sample : -

Stage : -

Immunohistochemistry, immunoprecipitationUp-regulation-CD164 is highly expressed in the colon cancer sites, and it promotes HCT116 colon cancer cell proliferation and metastasis both in vitro and in vivo


Gene Details



NC_000006.11 (109687717..109703762, complement)

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Gene Type protein coding
Gene Family CD molecules
Description Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor (Watt et al., 1998 [PubMed 9680353]; Forde et al., 2007 [PubMed 17077324]).[supplied by OMIM, Aug 2008]  
Chromosome 6
Location 6q21
Start 109687717  
End 109703762  
Strand -  
Gene Sequence

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Length 16046  
OMIM ID 603356   
HGNC ID HGNC:1632   
Unigene ID Hs.520313   
Ensembl ID ENSG00000135535   
PharmGKB ID PA26191   

mRNA Information


mRNA ID ?NM_001142401.1
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS47462.1



Protein Information


      
Protein IDNP_001135873.1
Protein NameCD164 molecule, sialomucin
Molecular Wt. (Da)0
Protein Sequence

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Length 197  
Uniprot IDQ16825
Ensembl Protein ID ENSP00000330276  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


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No matching records from HPRD source could be found.

Pathway Information


      
Pathway Name Pathway ID
Lysosome hsa04142


Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam052834-189  MGC-24


Ontology Information


   
HPRD ID6690
Molecular ClassAdhesion molecule
Molecular FunctionReceptor signaling protein tyrosine phosphatase activity (GO:0004728)
Biological ProcessCell communication (GO:0007154); Signal transduction (GO:0007165)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO