CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
BCL10	8915	B-cell CLL/lymphoma 10	1	CLAP; mE10; CIPER; c-E10; CARMEN

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
22997602	2012	Cell line : - Source : - Sample Type : - No. of Sample : - Stage : -	-	Mutation	-	Mutation due to inactivation of DNA mismatch repair system results MSI

Gene Details

Chromosome: 1; NC_000001.10 (85731459..85742587, complement)
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Gene Type	protein coding
Gene Family	-
Description	This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. [provided by RefSeq, Jul 2008]
Chromosome	1
Location	1p22
Start	85265776
End	85276904
Strand	-
Gene Sequence	>gi\|568815597:c85276904-85265776 Homo sapiens chromosome 1, GRCh38.p2 Primary Assembly CCCGAAGTGAGCAGGCAGCAAAGGCTGAGAGTGCCAGCTGCCTGGGCACTGACGGACCCCACCCACGGAA ACGATGCCTTATGAGGAAGCTAACCCGGGCCACTTACCGACGACCTGCGCAGGCGTGGCTTGAGGAAACG CCCGCTGTGGGCGGAGCCACCCGAAAGGCTCCGGTCGGGGGCGGGAACAGGATCGGCCCGCGGGCTGGCG TCGATAGGCTGCCGCAGAGACAGGGCGGGCTCTGCTAAGCGACGCGCCTCGCCGTGGGGCGGTGCCTGCG CCTGAGCCTCTACGAGAGGGAAGGAACGCTGCTCCGAGCTCCGCGTCGCGTCGCGTAGATTCGCGTCGCC GTCGACCTCAGAGGCGGGGCCGGAAGCGCTACGGTTTGACCCCCGAGTCCCTCTGTTCCCGAAGGGGCGG CCGTCTTTCTCCCGACCCGCTCCGCCTCCTCTCCTTCTTCCCCATTACCCGGAGGCCGAAGCCCCCAGCC AGGGCGGGGCGGCGCAGCCCGAGCTCCCGGACCCGGAAGAAGCGCCATCTCCCGCCTCCACCATGGAGCC CACCGCACCGTCCCTCACCGAGGAGGACCTCACTGAAGTGAAGAAGGACGTGAGTAACGCAGCTGTGCCC AGGGCGGGCGGGGGCGGGCTGCAGCCCAGCGGGAGACGAAAGCGGAAGCCTGGAGTCCGAGGACAAGGAG GATCCTCCAGGTCGGAGGAGCGGAAAGTCCTAGCACAGGAGGACTGTGGCGAGCCCTGCATCCGAGGGAC CTTGGTGGCAGTGATCCTCCAGTGATCTGTCAATCCAGGTTTTACATCGCTAAACGCAGAGCTTGGGCTT TGTTGCCAAGTGGTGTTTTGATTCTTGCCCACTCCTCACCCATCTCCTCATGCTTTCCCCCCAACTGGGT TCTTGGAGATGCTTCGTTAGGGACTGGCGGCTCAGATTCATCCTTAAGTCAGGCTGCCTAGGCTGCTCAC TCAGCCTAGAGCGAAGGCTGTACCAGGTGAAGGATCCCAAGCAGTGGACCAAAAATGTGAAGCTCTTTTG CATAAGGGGGCTTGAGGAAGCTCAACAGCTGAAAGCACAACCTGGAATTCCCCTAGTAAGCAGACGCCCA CATATTTAAATTGGGGTTGGGGGAGTGAATACACGTAGCTGAGAATTAATGTACAGGTAAACGTCGAAAA TATTCAGTAGCTAAATTATGCTCTTCTCGGATGGTGCAGAACCACATAAACCTTCATATTTATTCGTAAC GAATGGCTTTGTTGAGATATGACATTCTTTTTCCTTTGCGTTTACTTGTTTTGTCAGATGAGACCTATAT GAGTATCACTAAAATACTTTATCTGAAGTCAAATGAAAAACAGAAACTCAACATGAAACGTGTTCTTATT GAACACTGCAGTACTTTTACAAAGTCATTTTGATGAACTGGACAGGATGGCAACTTTTTAAATGTTCATC CACTTCAAATCCCTTCCTCTTCCCTGTAAGGTTTATTACACTGTACTCACAATTGGTGTGACTCACCAGC AGAAGGAAACTGGATATGACTGGGAGTTGTGCTTAGTTTCCTCATTCAACAGAGATTTATGGAGCACTTG CTATATGGAAAGCACTGGCCTTGGGTCTGGAAGGATACAAAAAAATGAAGATCAGTTTCCTGCTTTACAT TCTAGTTGAGATAAGAATGGAACATAAATAACTACTGTAGAATAAATGTTGTCTTATTCATGGTGAGTGC CAGTAAAACCTTGAACTTCCAAGAGCTAGGCCTCCTATGTTCCAGATGCTGTGTCACACAGTTTACAATG TTCCCACTTAACCTTCGCAACAACCTCTAAAGAAGATAATTGCCATTCCCATTTTACAGCTAATAAAACA GGAACTGAGAAATTACAAGTGGAAGGAAATAAGATCTGTATACAAGTACAGATGTGAAGAGTGGCTTCCA GGTCTTTGTTCTTCTCTGTCAATTCATTGATGTTATCTGTCTTCAGGATTTCATTTTACGCCTATATCAG AAATAAATAACCTTGAGGAAACCATGGATGGGTTTCAAAAGGTCTATGAAAGAAACTATGTGCATGCTTT TTTCTTAGAGGTTTTTTTCATGATATTTTCAAAATGTCTTCTGATCTTAGAGAGTTTTAAAATTATCCAC ATATTTGGACTTTTCTCTCCACTCTAGGTCCTTATTTCCAAATGTCTACTGGAAATCTACTTTTATATCC TACAGATTGCTCACCTTGTCAAATATTGAACTTTTACTATCCTTTTCCCAAAGTTGCTTACTGTTGCTGC TGTATTGCCTTTCTTGATGAATGGTGTGCTACCACCCTTTGTCTTGGGACCTCCCACTTCTTTAGTGTCT CCCCCTCCTCCTATCTAGTTATTTGCCTCATTGTGTTAGTTGGATTTAGTACAGTTTAATAAATATGGAT TACATGCTACTGTGAGGCTGATACTGTGGTTGGTTCTAACAGTTCAAAAATTAAAAATGAAAACACAATC CTAACTTGAAAAGAGCTCAATTTCTTGAGGGGGATTGTTTTAAATCACAAAATAAGTGCAGTGAGTTTTG CATTCAACTGAAACATTAACTACTTGGTGCCCTAGTAAGTGCAGGATATACAGTGTTGGCTAAAACATAC CTCGTAGCTGCCTGCTTCAAACAGAGACGTTAGTTTAAAACAAATAAATAAATTTTGTTTTCATTATTGC AATTACTATGAAGGAATCAAACAGTGCCAAGACAATAATAGGGGAAATCGACTTGAGATAGGATGGTCAG GAGAGGTTATATTTAAACTGATTCCTGAAAGATTTGACAGAACTGAGGGAAGAGCATTCTGGGCAGAATA GAATTTGTCAAGGACCTAAAATAGGCAAGACCCTGGTGACTTGGGGAAATCGGAGGAAGGCAGAGGGTAA TCTGAAGTGAAGTTAGGAAGGTGGGCTAGAGCCATTTTCATGAAGAGCCTTTTAGTAAAGTATCTGGGGT TTTTTTCCCCCCAAGTATAGTAGGGACTTGTTGAAGAATTGTATAGTTTAAAGATCCCTCTGCCTGTTTC ATGGACTGAGGAGAACAAGAATAAGAACAGGGAAGCCAGTGAGCAGGCTCTTGGAATCTATAGAGATGAA TGAGGATGGTGATTTGGATCAGGGTGAAGGCAGTGGAGATGAATGGAGCAGAATTCCAGATGCAGTTTTT GAAATAGAAATGATATGACCTGGTGATGGATTGAACATGGGAGTTGAGGAAGAGGATGTAATTAGATTAG TACATGGAAATGTCAGATCAGCAATTACATCTGCAAAGTCAAAGATCAGAAGAGAGATCTGAGCTAGAAA TGTAAGTGTGGAATTGAATGATTTTACCTAGAAAGCTGTGAGCTAGAAGAGAAAAATGGTGTAAAACCCT TTAAAGAGAAGAATTTTAAAAAGTGAATTGTTAGCTTGAAAGTAGGGTAACAACAACAACAAGAAAATGA TTGAAAAGTTGTATCCACAGGGATGGGAAGAAAACCAGGAGAGTGTGGTATTCATGTAACAATTTTCTTG TTTCAGGGAGGGAGTAGTCAACTGTGTTTATGCAGCTGAAAAATGAAATGAAGACTGAAAATATTTGGCA ATAAGGGGGTCATTGGTGACTTCGAGAAGAATACTGGGGCAGGATGGAAATGTCTGGGAATGAATTGGGA AATGAGGTGAAAGAAGTGGAGTCCTGGTGTATAGAAAGATGAAGTGTATACACAAGGTGCTACAAGGACA GAGGACGGGGTGCCTAACTCATTCTGGGGAGTTAGGTAAACCTTTCCAAAGAAGATGACCACTGACCTAA ATCTTAAAGGACGAATAGGGGCTTTAGGGTCTGATAAAAGCAGACAAAAAATACGTAAGGAAATGTAGAG AGACAGATAGTTTTAGGTAGAGCATAAATTTTCAGGACAAAGGTAGTGATAGATTAAGCTGGAGAGGTAG GTAGGAGCCATATTATCAATGAACCTTGTCTTCCATAATTAGTTATTATTGAGTACTTACTGTGTACAGA GACTATGCGTGGCCTTCATATATAGTATTCCCATTTAGTCCTCCTTGATGTCCTGTGAGTTAAGTTTTTA ATCCTTATTTTATCAATAACATACCTGGAGCTTGGAGTGGTGAAGTAACTTGGCCCAGCTCTCACAAGGG TGAGTACTAGATTCAAGATTTGCACTGAGGTTGATCCAACTTTAGAGCCATGCCCTTAACTTTTCTACTC TTCTGCCACGTAAAGGAACTTTATCCTTTAAGACAGGGCAGAACATTGTTTTTAATTTTTTTTCTAAATT AACAAAATTTCAATATTAGAATTTGCTGGGCACAGTGGCCCACACCTATAATCCCAACAACTCAGGAGGA TAAGGTGGGAGGATCACTTAAGGCCAGGAGTTCAAGACCAGCCTAGGTAATGTAGCAAAGATCCCTTCTC TACAAAAAAAAAAAAAAAAAATTAAAAATTAGCCGGGCATGGTGGCTCACACCTGTAGTCCTAGCTACTC AAGAGGCTAAGATGGGGATCACTTGAGTCTAGGGATTCCAGGCTGCAGTGAGCTATGATCAAGCCACTGC ACTCCAGCCTAGGTGACAGAGTGAGATCCTTAAAAAAAATTTAGTAAAATTCATATAATACTCCAGATTT CCATTTTCTCCTGAAGGAGAAATGTTGAGGAGGGGGAAGGAAGTAGTAAGTGCAGCTAGGTTTCTATTGT TAATAGTCCATGCCAGATATGATAAGGACCAGGTCCTGGACATAGTTATTTGCTCACTCTGTGCTTTTCC TGTATTTGACCTATAATCTTTTTTTTCTGGGCCCGATCACATTGTTTTATAATTATTACCTGTGATATGT ATTCCCAGCTAGACCATGAGCCCTTTGCATGTAGGATTCAAATCTTGTTCATCTTTGTATACTCAGTGCT CAGCACTCGGCATATTAGGAATTTAGATTTGTAAAATACTTGTCATGTGAATAAACAAGTAAATGTGGAA CTTCGTAGACCAAGAACCACAGGAACCCTTCACCTAGCCTACTTTCCTGCCATTACCTTTGTCATTATTA CTAACATATATTGATCACTTACTATGTACCAAGCGCTTTTCTAAGCACTTTGCATATCTTTATTCCTCAT ATAACAGTCAGCTGAGGAAACAAGCACAGAGGAGTTAATTACTTGCCCAAGATCATATATCTAGTAAATA GAGGAGCTAAAATACAGTCACCGGTACCAAATTATTAATGCCATTTATTGAGATCAACATGGATTTTCTA CTAATTAAGCTCTTAGGCACTTCTCAAATCTAGGTTTGCTTTTTTGTGGTGTCCTTTTTCTTTATTTCTT TCATTTTTCGAACACTCCCTATTCCCCACACATCTTTCCATCTCCCTTCCACCAAGACTGATTCACTGAG TTAGAGTGTAGTCTTTCCAGCTGACCCCAAAGACAGATACATTATGGGCTCTTTCAGTTTAGGGTTTTGT TTTTTGTCTTTAACAGTTTAAGGAAATGGAGTAATTAATAACAAACATGAGAAAGTTACAGACTGTGAGA CCTCTCACTAAGTTATTGGTCCTGACTAATTCTGCATTCCTTGCCAACTGATAGCTAAAATGTACAGTAG TGTTTGCCCTCATCTTTACTCCCGAAGATGGCCCTCAACAGACCTCCCTGTTTCCAAGGACCCAGGCCCT CTAGATTCAGCTGGTCCCTCTTCACAACAGCCTGGTCTTGGTTTTTAGGTTTGAAGGTGAGATCAAAGCA GTGAGGAATGTCTAGGACCTACTTGTGTCTACTTGGACTTTCATCTTAATTAGCATGCATTTTAGAAGGC CTGAGCCTCCTGACTTTAGAACATTGTCTCACACCAGCTAAGACTGCCAACTAATAGTCACGTATGTGAT TTTCTTAGATGTTAAAAATAACATTGAACCATATTTTATGTCTTTTAGGCCTTAGAAAATTTACGTGTAT ACCTGTGTGAGAAAATCATAGCTGAGAGACATTTTGATCATCTACGTGCAAAAAAAATACTCAGTAGAGA AGACACTGAAGAAATTTCTTGTCGAACATCAAGTAGAAAAAGGGCTGGAAAATTGTTAGACTACTTACAG GAAAACCCAAAAGGTCTGGACACCCTTGTTGAATCTATTCGGCGAGAAAAAACACAGAACTTCCTGATAC AGAAGATTACAGATGAAGTGCTGAAACTTAGAAATATAAAACTAGAACATCTGAAAGGTAAGATATCTTA ATTATCTAAGAGCTAATTTAAATGTAATAATGCTTTTAAAAAATGCAGAGCAGGCCAGGTGCCTGCACTT TAGGAGGCCAAGGCAGGAGGATTGCTTGAGGTCAGGAGTTTTGAGACCAGCCTGGGCAACATAGCGAGAC TTTGTCTCTACAAAAAATTAAAAAATTAGCCAGGCATGATGGTGCATACCTGTGTTTCCAGCTACTCAGG AGGCTGAGGTGGGAGGATCACTTAAGCCTGGGACATTGAGGCTATAGTGAGCCATGATTGTGCTACTGCA CTCCAGTCTGGGCAACAGAGCAAGACCCTGTCTCAGAAAAGCAAAACAAAAACAGAAATGATCATTTTGC TTTCAAAAAGTTTAAACTTCAAAATTATATTCAATTTGCACTTATTTTACCTTATTTGACACTATTACAT TGAAAAAGTGGAATATCTCTCAATATCCTGTATTTGTATTCATTTAATACCATTTATAGAAAACTATTAT GAAATCCCTGCATACATAAGGATTTGTTTCTAAAGTCAGTAGAATGTAAAGTTAATCTATTCAAGAGTAA GCTCTGAAAATACTGTACATCACACATAAAGAACAGTATTTAGGCAAAGTATTGTAAAAGTCCAACTCTG CTAGTTTTTCTTATGATCACCAGTTGATCACAAGATGAAGTAATTGGCATATGTTTATAGGAATCACGTT GCATAAAATATTCATGACTTTAAACTAGTCTGGCAAGATGTGAAAGCATGGAAACAGATTAAGAGAATAG CAGATTCACCTGTCCCATTTCACTCTCACTCCAGAATATACACTCACTGATTGGAATATTGTGTGGAATT GCCTACACAATTTAAATCCCCAACCCCCTCCTGCCTCTGTTCCTCACTGTCTCTCTCCAGAGCACATAAA TGTGCATGTGATGTTCTACAGCTCTTCTAGGCATTAGGGATACAGAAAAGAATAATTTAGGGCTCTGCCC TTAAGGAACTCATAGTCTATAAGTGTCCCCTTGCTGGGACACATTACAAGTTTTCCCTTTTGAGCCATAT CTAAGAAAGTAGTTTGTATAGCATGGAATAGACATGCTGACTGTACTGTGAGGTTGAAAAACTAGTGGAA GAAGTGACATGTAAGTGCCCTTTATAGACTATGCAGGTTTTGCCTAAAAATTGTCAACTCAGGGTTTCTG TGCCTGTAGGTTGAATATTTGCTAAGCCTAACAGAAGGGTAAATTGTGTTTGTGTTTATTCTTTCAATCC TCTGGATAATGGTTAACTATACCCTTTGGATATCATAAAATTCTTTGATGGTATCTAAGTTGTTTTCTGC TGTAGCAATACCTGAGACTGGGTAACTTTTAAAGAAAAGAAATGTATTCATTTCTTACAGTTCTGGAGGC TGGTTAAGTCCAAGACCATGGCGCCAGCATCTGGCAAGGGTCATGCATGGTGGAAGGGCAGAAGATGGAA GAGCAAGGGAGGGCAAGAGTGTGAAAGAGAAGAAAAAGGAGTCGAACTCCCAAAATAACTAACCCATTCC CGTGATAATGGCATTAGTCCAGGGCAGAGCCCTCATGACCCTGTTGCCTCCCAAAGGCCTCAGCTCCTAA CACTGCTGCAGTGGCAACCAAGTTTCCAACATGTGAACTTTTGGCGGATACATTCGTACCACAGCTAATG GGAACAACCACTGTCATTTGAGTAAACTGTGAGGTTGAGAAACAGGACATTATCTATTGAATTGTAGTTC TCACTTTCCCACAAAGTAGTCCTGGAATGTTGGACATGACTTAACTGTCCTGTGCCTTTTTTTTCTCTTT TTTTTTTTTTTTTTTTGAGACGGAGTCTTGCTCTTGTCACCCAGGCTGGAGTGCAATGGCATGATCTCAG CTCACTGCAACCTCTGCCTCCCAGGTTCAAGCGATTCTCCTACTTCAGCCTCCTGAGTAGCTGCGATTGC AGGCACCTGCCACCACGCCTGGCTAATTTCTGTATTTTTAGTAGAGATGGGGTTTCGCCATGTTGGCCAG GCTGATCTCAAACTCCTGACCTCATGATCTGCCCACTTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTG AGCCACCATGCCCCGCCCTTTTTTCTCGTCTTTAATAATAAGAGACTATCCTAGGTGACCTCTAAAATTC CTTTTAGTTCTAATATCCTATTATTCAAGAATTAGCCATTGTCATTGATCAACAGATAGAATTTTAGCAT CTGCCGTTTACATTTTTTTATTAGCTAATATTTTTTGTACCAGAATACTAAAGAATATTTATTGTGAAAG CTATTTCTTATTTTATAAAAAATTTTAGGTGGTTAAGTTTATATGTACGCTGTACCTTAAATGAGAATTA CAGCATGTCGTTTAACTTCCACGAGACTATTTTGTTATATAGAAAATGCAAATAATAGTATACTTCATGG TTGTTGAGAAAAGCAAATTAGATTTGAAATAGATTATGACGGAAATTACAAGTTGCTATTTAAATTTTGA TTGTGGGGTAACTAGCTTGTAATCTTTAACAAGTCACAAGATGGACAGTGACTCCATTTTTTTAGTTACT TTTTCATTTACATCTGAATAATTTTATTGTAGGACTAAAATGTAGCAGTTGTGAACCTTTTCCAGATGGA GCCACGAACAACCTCTCCAGATCAAATTCAGATGAGAGTAATTTCTCTGAAAAACTGAGGGCATCCACTG TCATGTACCATCCAGAAGGAGAATCCAGCACGACGCCCTTTTTTTCTACTAATTCTTCTCTGAATTTGCC TGTTCTAGAAGTAGGCAGAACTGAAAATACCATCTTCTCTTCAACTACACTTCCCAGACCTGGGGACCCA GGGGCTCCTCCTTTGCCACCAGATCTACAGTTAGAAGAAGAAGGAACTTGTGCAAACTCTAGTGAGATGT TTCTTCCCTTAAGATCACGTACTGTTTCACGACAATGACACTTTATTGCCTTTTAATTTTTAATGATGAC AAAAAATGTTTTAAAGAATATGACTTTTTATAAAATGGCTGTAATCATTTGTTTACATTTGATGCATGTC TTTTAAAATGCAATGTAAGCATACTTTGTAAATAGGATTTTTAGAATTAAAAAAGCATACTTCTAGGATA GCTAACTGTAAATCATGTTGATCATGTACTTTTTAGTAATTTCTTTTTTTCCTTTTTAAGGTCTTTCAGT ACTTTTTTAAATATTTTCTATTTTAAGACTGATTTTAATAGGGAATATATCTCTATTTGAGAATAGACCC TTACTAGGAAGAACGTTTTTTCCTCAGTGCATTTGTGCTAGAAATTTTCAAGAGTCTAATAGTCTTTGCC AGTCATTCAGCAGCAAATTTTCAGCATTAAGCTGTTCCTGTTCAGTAATAAAACCGGTCACTGATGGGAA AACTGCCAATATAGAAAAATAAAAATCTCTTTTCCACTCCATTGTCGTATAGGCATGTAAACAGCCTCTT TTTGATACTGGAGGAACACTTGATGGAGTGTGAGCCACCTAAGATCTCGGTTTGCCAAAATTCATTTCTA ATTAACCTTACTAATTATACTACTTTGTTAGGATTTTCACATTCTTGGCTTAATCATTTTCATTCCTAAA GAAAAATATCTTGGCCTAAACCTCAGTTATTACATGTAATTTGATGAGGTATTTTTTCCTTTTTTCTTTT TTTTTTTTTTTTTTTTTTGAGACAGTCTTGCTCTATCGCCCAGGCTGGAGTGCAGTGGCGCATTCTAGGC TCACTGCAACTTCTGCCTCCCATGCTTACGTGATCCTCTCACCTCAGCCTCTCAAGTAATATAGCTGAGA CTACAAGTGTGTGCCACCATGCCTCACTAATTTTTGTATTATTTTTGTAGAGACGGTGTTTTGCCATGTT GGCCAGGCTGGTCTTGAACTCCTGGACTCAAGCAACCTACCCAGCGTGGCCTCCCAAAGTGCTGGGATTA CAGACACGAGCCACCTCACCTAGCCTGATGAGATTTTTAAAAAATATTTTCTCTGTACTTTTCATTCTCT TTTAATGAGGACCAATGTACAGTTGAAATAACTGGAACAAATTATTTTTGGTGTGTGTGACAATTCTGTT TTTAATGCTATTTGAACAAGTGGGCCATTAGCCAGATTTGTCTTTTTGTTGTAAAACAAAATTTGACTAA TTTTACATGTTTATAAATCTTATGCTCTCACTGTTTGTTTTTATTTAAATTACAATTTTATCTGTTTCCT GACATTGTCTCCTATATATTTCTATTATTAATTGCAAAAACATAGAAATGGAAATTTTGCTATCAACAAT AAAATTTTTTTAAAGTAGTGAGTGCTATTTTGGAGTTCCAAATTTTCAGTAGGAAGTATCTAAAACTTTT TTTAATACGTGCCATTATCTATAGAAAACATTACTTCAGGTTGTGAGATTGAGTTGCATTTCTGGATGGA CTGATGAATTTATCCGACATGAAGAAGATTGGCATATTAGCTTTAAAAATTTTTAAAGATTGGATTTTTT TTAGTATAAGCACTTTCTAAGGATTATAGAGAAATGTTTCACCTCCAATGCATAGCAAAAATAGTGGTGT TAGAAAGAAAATAGGTTACATTTAAGGAAGGTGCTTTAAAAAGCAGAAGCAGACTTTAAAATTAAATTTG TGGACACCTTTTTAAAAATTGAATCAAAGATTATAATTTAGATATACAATAACACCTATATATAGATAAG TTTTAACACTGAGTTTTCTTTCAGACTGTTTTCTAACTACATAGACAATAAAATTAAGCTTTGCATAAA Download Select all
Length	11129
OMIM ID	603517
HGNC ID	HGNC:989
Unigene ID	Hs.193516
Ensembl ID	ENSG00000142867
PharmGKB ID	-

mRNA Information

mRNA ID	NM_003921.4
Exon	join(1..609,5999..6287,8923..11129)
mRNA Sequence	>8915 CCCGAAGTGAGCAGGCAGCAAAGGCTGAGAGTGCCAGCTGCCTGGGCACTGACGGACCCCACCC ACGGAAACGATGCCTTATGAGGAAGCTAACCCGGGCCACTTACCGACGACCTGCGCAGGCGTGG CTTGAGGAAACGCCCGCTGTGGGCGGAGCCACCCGAAAGGCTCCGGTCGGGGGCGGGAACAGGA TCGGCCCGCGGGCTGGCGTCGATAGGCTGCCGCAGAGACAGGGCGGGCTCTGCTAAGGGACGCG CCTCGCCGTGGGGCGGTGCCTGCGCCTGAGCCTCTACGAGAGGGAAGGAACGCTGCTCCGAGCT CCGCGTCGCGTCGCGTAGATTCGCGTCGCCGTCGACCTCAGAGGCGGGGCCGGAAGCGCTACGG TTTGACCCCCGAGTCCCTCTGTTCCCGAAGGGGCGGCCGTCTTTCTCCCGACCCGCTCCGCCTC CTCTCCTTCTTCCCCATTACCCGGAGGCCGAAGCCCCCAGCCAGGGCGGGGCGGCGCAGCCCGA GCTCCCGGACCCGGAAGAAGCGCCATCTCCCGCCTCCACCATGGAGCCCACCGCACCGTCCCTC ACCGAGGAGGACCTCACTGAAGTGAAGAAGGACGCCTTAGAAAATTTACGTGTATACCTGTGTG AGAAAATCATAGCTGAGAGACATTTTGATCATCTACGTGCAAAAAAAATACTCAGTAGAGAAGA CACTGAAGAAATTTCTTGTCGAACATCAAGTAGAAAAAGGGCTGGAAAATTGTTAGACTACTTA CAGGAAAACCCAAAAGGTCTGGACACCCTTGTTGAATCTATTCGGCGAGAAAAAACACAGAACT TCCTGATACAGAAGATTACAGATGAAGTGCTGAAACTTAGAAATATAAAACTAGAACATCTGAA AGGACTAAAATGTAGCAGTTGTGAACCTTTTCCAGATGGAGCCACGAACAACCTCTCCAGATCA AATTCAGATGAGAGTAATTTCTCTGAAAAACTGAGGGCATCCACTGTCATGTACCATCCAGAAG GAGAATCCAGCACGACGCCCTTTTTTTCTACTAATTCTTCTCTGAATTTGCCTGTTCTAGAAGT AGGCAGAACTGAAAATACCATCTTCTCTTCAACTACACTTCCCAGACCTGGGGACCCAGGGGCT CCTCCTTTGCCACCAGATCTACAGTTAGAAGAAGAAGGAACTTGTGCAAACTCTAGTGAGATGT TTCTTCCCTTAAGATCACGTACTGTTTCACGACAATGACACTTTATTGCCTTTTAATTTTTAAT GATGACAAAAAATGTTTTAAAGAATATGACTTTTTATAAAATGGCTGTAATCATTTGTTTACAT TTGATGCATGTCTTTTAAAATGCAATGTAAGCATACTTTGTAAATAGGATTTTTAGAATTAAAA AAGCATACTTCTAGGATAGCTAACTGTAAATCATGTTGATCATGTACTTTTTAGTAATTTCTTT TTTTCCTTTTTAAGGTCTTTCAGTACTTTTTTAAATATTTTCTATTTTAAGACTGATTTTAATA GGGAATATATCTCTATTTGAGAATAGACCCTTACTAGGAAGAACGTTTTTTCCTCAGTGCATTT GTGCTAGAAATTTTCAAGAGTCTAATAGTCTTTGCCAGTCATTCAGCAGCAAATTTTCAGCATT AAGCTGTTCCTGTTCAGTAATAAAACCGGTCACTGATGGGAAAACTGCCAATATAGAAAAATAA AAATCTCTTTTCCACTCCATTGTCGTATAGGCATGTAAACAGCCTCTTTTTGATACTGGAGGAA CACTTGATGGAGTGTGAGCCACCTAAGATCTCGGTTTGCCAAAATTCATTTCTAATTAACCTTA CTAATTATACTACTTTGTTAGGATTTTCACATTCTTGGCTTAATCATTTTCATTCCTAAAGAAA AATATCTTGGCCTAAACCTCAGTTATTACATGTAATTTGATGAGGTATTTTTTCCTTTTTTCTT TTTTTTTTTTTTTTTTTTTTGAGACAGTCTTGCTCTATCGCCCAGGCTGGAGTGCAGTGGCGCA TTCTAGGCTCACTGCAACTTCTGCCTCCCATGCTTACGTGATCCTCTCACCTCAGCCTCTCAAG TAATATAGCTGAGACTACAAGTGTGTGCCACCATGCCTCACTAATTTTTGTATTATTTTTGTAG AGACGGTGTTTTGCCATGTTGGCCAGGCTGGTCTTGAACTCCTGGACTCAAGCAACCTACCCAG CGTGGCCTCCCAAAGTGCTGGGATTACAGACACGAGCCACCTCACCTAGCCTGATGAGATTTTT AAAAAATATTTTCTCTGTACTTTTCATTCTCTTTTAATGAGGACCAATGTACAGTTGAAATAAC TGGAACAAATTATTTTTGGTGTGTGTGACAATTCTGTTTTTAATGCTATTTGAACAAGTGGGCC ATTAGCCAGATTTGTCTTTTTGTTGTAAAACAAAATTTGACTAATTTTACATGTTTATAAATCT TATGCTCTCACTGTTTGTTTTTATTTAAATTACAATTTTATCTGTTTCCTGACATTGTCTCCTA TATATTTCTATTATTAATTGCAAAAACATAGAAATGGAAATTTTGCTATCAACAATAAAATTTT TTTAAAGTAGTGAGTGCTATTTTGGAGTTCCAAATTTTCAGTAGGAAGTATCTAAAACTTTTTT TAATACGTGCCATTATCTATAGAAAACATTACTTCAGGTTGTGAGATTGAGTTGCATTTCTGGA TGGACTGATGAATTTATCCGACATGAAGAAGATTGGCATATTAGCTTTAAAAATTTTTAAAGAT TGGATTTTTTTTAGTATAAGCACTTTCTAAGGATTATAGAGAAATGTTTCACCTCCAATGCATA GCAAAAATAGTGGTGTTAGAAAGAAAATAGGTTACATTTAAGGAAGGTGCTTTAAAAAGCAGAA GCAGACTTTAAAATTAAATTTGTGGACACCTTTTTAAAAATTGAATCAAAGATTATAATTTAGA TATACAATAACACCTATATATAGATAAGTTTTAACACTGAGTTTTCTTTCAGACTGTTTTCTAA CTACATAGACAATAAAATTAAGCTTTGCATAAAAAAAAAAAAAAAA Download Select all
Length	3118

CDS Information

Location	join(553..609,5999..6287,8956..9278)
CDS Sequence	>lcl\|NM_003921.4_cds_NP_003912.1_1 [gene=BCL10] [protein=B-cell lymphoma/leukemia 10] [protein_id=NP_003912.1] [location=553..1254] ATGGAGCCCACCGCACCGTCCCTCACCGAGGAGGACCTCACTGAAGTGAAGAAGGACGCCTTAGAAAATT TACGTGTATACCTGTGTGAGAAAATCATAGCTGAGAGACATTTTGATCATCTACGTGCAAAAAAAATACT CAGTAGAGAAGACACTGAAGAAATTTCTTGTCGAACATCAAGTAGAAAAAGGGCTGGAAAATTGTTAGAC TACTTACAGGAAAACCCAAAAGGTCTGGACACCCTTGTTGAATCTATTCGGCGAGAAAAAACACAGAACT TCCTGATACAGAAGATTACAGATGAAGTGCTGAAACTTAGAAATATAAAACTAGAACATCTGAAAGGACT AAAATGTAGCAGTTGTGAACCTTTTCCAGATGGAGCCACGAACAACCTCTCCAGATCAAATTCAGATGAG AGTAATTTCTCTGAAAAACTGAGGGCATCCACTGTCATGTACCATCCAGAAGGAGAATCCAGCACGACGC CCTTTTTTTCTACTAATTCTTCTCTGAATTTGCCTGTTCTAGAAGTAGGCAGAACTGAAAATACCATCTT CTCTTCAACTACACTTCCCAGACCTGGGGACCCAGGGGCTCCTCCTTTGCCACCAGATCTACAGTTAGAA GAAGAAGGAACTTGTGCAAACTCTAGTGAGATGTTTCTTCCCTTAAGATCACGTACTGTTTCACGACAAT GA Download Select all
CCDS ID	-

Protein Information

Protein ID	NP_003912.1
Protein Name	B-cell CLL/lymphoma 10
Molecular Wt. (Da)	26121
Protein Sequence	>8915 MEPTAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKR AGKLLDYLQENPKGLDTLVESIRREKTQNFLIQKITDEVLKLRNIKLEHLKGLKCSSCEPFPDG ATNNLSRSNSDESNFSEKLRASTVMYHPEGESSTTPFFSTNSSLNLPVLEVGRTENTIFSSTTL PRPGDPGAPPLPPDLQLEEEGTCANSSEMFLPLRSRTVSRQ Download Select all
Length	233
Uniprot ID	P52799
Ensembl Protein ID	ENSP00000245323

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
S	Phosphorylation	138

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
207	AKT1	1261	NP_005154.2	in vitro	16280327
842	CASP9	3756	NP_001220.2	in vivo	10187815
1147	CHUK	2811	NP_001269.3	in vivo	11113112
7186	TRAF2	3538	NP_066961.2	in vivo;yeast 2-hybrid	10753917
7334	UBE2N	4725	NP_003339.1	in vitro;in vivo	14695475
7336	UBE2V2	4300	NP_003341.1	in vitro;in vivo	14695475
8517	IKBKG	2217	NP_001093326.2	in vitro;in vivo	14695475
8717	TRADD	4610	NP_003780.1	in vivo	10400625
9021	SOCS3	5006	NP_003946.3	in vivo	15213237
57161	PELI2	17835	NP_067078.1	in vivo	15213237

Pathway Information

Pathway Name	Pathway ID
B cell receptor signaling pathway	hsa04662
NF-kappa B signaling pathway	hsa04064
T cell receptor signaling pathway	hsa04660
Tuberculosis	hsa05152

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd08810	17-100	CARD_BCL10
cl14633	17-100	DD superfamily
cd08785	17-100	CARD_CARD9-like
pfam00619	18-102	CARD
cd01671	25-88	CARD
cd08809	21-100	CARD_CARD9
cd08327	18-86	CARD_RAIDD
smart00114	13-87	CARD

Ontology Information

HPRD ID	1494
Molecular Class	Adapter molecule
Molecular Function	Transmembrane receptor protein tyrosine kinase activity (GO:0004714)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO