Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| WNT3A | 89780 | wingless-type MMTV integration site family, member 3A | 1 | - |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24564183 | 2014 | Cell line : - Source : Seoul St. Mary Hospital Sample Type : CRC tumor No. of Sample : 83 Stage : - | Tissue microarray, immunohistochemistry | Up-regulation | - | Wnt3a and wnt5a expression had a concordance rate higher than 60% with a high concordance rate between the primary tumor and metastatic site. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Wingless-type MMTV integration sites, "Endogenous ligands" |
| Description | The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. This gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. [provided by RefSeq, Jul 2008] |
| Chromosome | 1 |
| Location | 1q42 |
| Start | 228194723 |
| End | 228248972 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 54250 |
| OMIM ID | 606359 |
| HGNC ID | HGNC:15983 |
| Unigene ID | Hs.336930 |
| Ensembl ID | ENSG00000154342 |
| PharmGKB ID | PA38074 |
Protein Information
| Protein ID | NP_149122.1 |
|---|---|
| Protein Name | wingless-type MMTV integration site family, member 3A |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 352 |
| Uniprot ID | Q96PU4 |
| Ensembl Protein ID | ENSP00000276893 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 6259 | RYK | 2751 | NP_001005861.1 | in vitro | 15454084 |
| 8321 | FZD1 | 4558 | NP_003496.1 | in vivo | 10557084 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Basal cell carcinoma | hsa05217 |
| Hedgehog signaling pathway | hsa04340 |
| Hippo signaling pathway | hsa04390 |
| HTLV-I infection | hsa05166 |
| Melanogenesis | hsa04916 |
| MicroRNAs in cancer | hsa05206 |
| Pathways in cancer | hsa05200 |
| Proteoglycans in cancer | hsa05205 |
| Signaling pathways regulating pluripotency of stem cells | hsa04550 |
| Wnt signaling pathway | hsa04310 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| smart00097 | 44-352 | WNT1 |
| cl19568 | 44-352 | wnt superfamily |
| pfam00110 | 41-352 | wnt |
Ontology Information
| HPRD ID | 11019 |
|---|---|
| Molecular Class | Ligand |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.