Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| HS6ST2 | 90161 | heparan sulfate 6-O-sulfotransferase 2 | X | - |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24649258 | 2013 | Cell line : - Source : Kinki University Hospital. Sample Type : Formalin-fixed, paraffin-embedded tissues No. of Sample : 102 Stage : - | Immunohistochemistry, RT-PCR,microarray | Up-regulation | 37 Fold | These findings indicate that HS6ST2 may be a novel cancer-related marker that may provide insight into the glycobiology of CRC. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Sulfotransferases, membrane-bound |
| Description | Heparan sulfate proteoglycans are ubiquitous components of the cell surface, extracellular matrix, and basement membranes, and interact with various ligands to influence cell growth, differentiation, adhesion, and migration. This gene encodes a member of the heparan sulfate (HS) sulfotransferase gene family, which catalyze the transfer of sulfate to HS. Different family members and isoforms are thought to synthesize heparan sulfates with tissue-specific structures and functions. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| Chromosome | X |
| Location | Xq26.2 |
| Start | 131760038 |
| End | 132095423 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 335386 |
| OMIM ID | 300545 |
| HGNC ID | HGNC:19133 |
| Unigene ID | Hs.385956 |
| Ensembl ID | ENSG00000171004 |
| PharmGKB ID | PA134950831 |
Protein Information
| Protein ID | NP_001070656.1 |
|---|---|
| Protein Name | heparan sulfate 6-O-sulfotransferase 2 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 605 |
| Uniprot ID | Q96PB8 |
| Ensembl Protein ID | ENSP00000379880 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
No STRING Network could be found.
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Glycosaminoglycan biosynthesis - heparan sulfate / heparin | hsa00534 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam03567 | 225-490 | Sulfotransfer_2 |
| cl22970 | 225-490 | Sulfotransfer_2 superfamily |
Ontology Information
| HPRD ID | 10571 |
|---|---|
| Molecular Class | Enzyme: Sulphotransferase |
| Molecular Function | Phosphatase regulator activity (GO:0019208) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.