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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
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- Enzyme
- PPi
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- Domain
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Evidence Information
No matching records could be found.
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | T-boxes |
| Description | This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012] |
| Chromosome | 6 |
| Location | 6q14-q15 |
| Start | 85442214 |
| End | 85473954 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 31741 |
| OMIM ID | 604613 |
| HGNC ID | HGNC:11595 |
| Unigene ID | Hs.251830 |
| Ensembl ID | ENSG00000112837 |
| PharmGKB ID | PA36358 |
mRNA Information
No matching records could be found.
CDS Information
No matching records could be found.
Protein Information
| Protein ID | |
|---|---|
| Protein Name | T-box 18 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 0 |
| Uniprot ID | Q14CN2 |
| Ensembl Protein ID | ENSP00000359594 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
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PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00182 | 139-334 | TBOX |
| cl00145 | 139-334 | TBOX superfamily |
| pfam00907 | 140-331 | T-box |
| smart00425 | 139-335 | TBOX |
| PRK00030 | 76-169 | minC |
| PHA03307 | 32-139 | PHA03307 |
| PHA03169 | 44-140 | PHA03169 |
| PRK07003 | 39-144 | PRK07003 |
Ontology Information
| HPRD ID | 6338 |
|---|---|
| Molecular Class | Not Available |
| Molecular Function | RNA binding (GO:0003723) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
SNP Information
No matching records could be found.
Drug Information
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External Links
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