Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| AURKB | 9212 | aurora kinase B | 17 | Aik2, IPL1, AurB, AIM-1, ARK2, STK5, PPP1R48 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20368716 | 2011 | Cell line : - Source : University of Southern California/Norris Comprehensive Cancer Center (USC/NCCC) or the Los Angeles County/University of Southern California Medical Center. (LAC/USCMC) Sample Type : CRC Tumor and normal tissue No. of Sample : 41 Stage : TNM Stage IV | Genotyping,real time RT-PCR | Polymorhpism | - | �Results suggest a potential role forAURKB�inhibition in patients with mCRC; thereby supporting its potential role as a target in mCRC. |
| 26259750 | 2015 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | RT-PCR array | Up-regulation | - | HDAC1, HDAC7, PAK1, NEK6, AURKA and AURKB are important diagnostic and prognostic markers involved in the carcinogenesis of CRC. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Serine/threonine phosphatases / Protein phosphatase 1, regulatory subunits |
| Description | This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromosomes 19 and 20. These kinases participate in the regulation of alignment and segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015] |
| Chromosome | 17 |
| Location | 17p13.1 |
| Start | 8108049 |
| End | 8113944 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 5896 |
| OMIM ID | 604970 |
| HGNC ID | HGNC:11390 |
| Unigene ID | Hs.442658 |
| Ensembl ID | ENSG00000178999 |
| PharmGKB ID | PA36199 |
Protein Information
| Protein ID | NP_001243763.1 |
|---|---|
| Protein Name | aurora kinase B |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 344 |
| Uniprot ID | Q9NTI5 |
| Ensembl Protein ID | ENSP00000313851 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| Y | Phosphorylation | 12 |
| S | Phosphorylation | 7 |
| T | Phosphorylation | 232 |
| T | Phosphorylation | 35 |
| Y | Phosphorylation | 92 |
| S | Phosphorylation | 313 |
| S | Phosphorylation | 227 |
| S | Phosphorylation | 45 |
| T | Phosphorylation | 236 |
| S | Phosphorylation | 61 |
| T | Phosphorylation | 64 |
| T | Phosphorylation | 16 |
| S | Phosphorylation | 62 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 332 | BIRC5 | 4520 | NP_001012271.1 | in vitro;in vivo;yeast 2-hybrid | 124 197 971 151 665 000 000 000 |
| 1058 | CENPA | 313 | NP_001800.1 | in vitro | 11756469 |
| 1674 | DES | 514 | NP_001918.3 | in vitro | 12686604 |
| 1731 | 1-Sep | 15324 | NP_443070.1 | in vitro;in vivo;yeast 2-hybrid | 16179162 |
| 3619 | INCENP | 5103 | NP_001035784.1 | in vitro | 12925766 |
| 5921 | RASA1 | 745 | NP_002881.1 | in vivo;yeast 2-hybrid | 11976319 |
| 7046 | TGFBR1 | 1822 | NP_004603.1 | in vivo | 15761153 |
| 8350 | HIST1H3A | 4155 | NP_003520.1 | in vitro | 10949293 |
| 10403 | NDC80 | 6277 | NP_006092.1 | in vitro;in vivo | 14602875 |
| 10607 | TBL3 | 9327 | NP_006444.2 | yeast 2-hybrid | 16169070 |
| 29127 | RACGAP1 | 5402 | NP_037409.2 | in vitro;in vivo | 126 895 931 474 485 000 000 000 |
| 54888 | NSUN2 | 8620 | NP_060225.4 | in vitro | 17215513 |
| 55139 | ANKZF1 | 7673 | NP_060559.2 | yeast 2-hybrid | 16169070 |
| 83540 | NUF2 | 10817 | NP_663735.2 | in vitro;in vivo | 14602875 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd14117 | 70-339 | STKc_Aurora-B_like |
| cl21453 | 70-339 | PKc_like superfamily |
| cd14007 | 76-328 | STKc_Aurora |
| cd14116 | 72-327 | STKc_Aurora-A |
| cd05117 | 76-326 | STKc_CAMK |
| cd14003 | 76-326 | STKc_AMPK-like |
| cd05123 | 83-326 | STKc_AGC |
| cd14099 | 75-326 | STKc_PLK |
| cd05581 | 75-326 | STKc_PDK1 |
| cd14663 | 76-326 | STKc_SnRK3 |
| cd05580 | 75-337 | STKc_PKA_like |
| cd14186 | 75-327 | STKc_PLK4 |
| cd14081 | 77-327 | STKc_BRSK1_2 |
| cd05572 | 83-326 | STKc_cGK |
| cd05579 | 85-326 | STKc_MAST_like |
| cd14073 | 77-327 | STKc_NUAK |
| cd05122 | 76-327 | PKc_STE |
| cd14008 | 83-327 | STKc_LKB1_CaMKK |
| cd00180 | 83-325 | PKc |
| cd14009 | 83-326 | STKc_ATG1_ULK_like |
| cd14014 | 77-320 | STKc_PknB_like |
| cd05573 | 75-337 | STKc_ROCK_NDR_like |
| cd14080 | 77-327 | STKc_TSSK-like |
| cd05612 | 75-337 | STKc_PRKX_like |
| cd14095 | 77-326 | STKc_DCKL |
| cd14002 | 75-327 | STKc_STK36 |
| cd14185 | 77-326 | STKc_DCKL3 |
| cd05570 | 83-337 | STKc_PKC |
| cd14079 | 74-326 | STKc_AMPK_alpha |
| cd08215 | 76-325 | STKc_Nek |
| cd14098 | 76-326 | STKc_Rad53_Cds1 |
| cd05578 | 77-326 | STKc_Yank1 |
| cd14069 | 76-327 | STKc_Chk1 |
| cd14189 | 80-324 | STKc_PLK3 |
| cd14209 | 75-328 | STKc_PKA |
| cd05571 | 83-337 | STKc_PKB |
| cd05574 | 75-328 | STKc_phototropin_like |
| cd14083 | 75-326 | STKc_CaMKI |
| cd06623 | 75-328 | PKc_MAPKK_plant_like |
| cd05575 | 83-316 | STKc_SGK |
| cd14074 | 77-327 | STKc_SNRK |
| cd14006 | 83-326 | STKc_MLCK-like |
| cd14167 | 75-327 | STKc_CaMKI_alpha |
| cd05584 | 83-337 | STKc_p70S6K |
| cd14072 | 77-327 | STKc_MARK |
| cd14103 | 83-326 | STKc_MLCK |
| cd14161 | 77-327 | STKc_NUAK2 |
| cd14096 | 77-327 | STKc_RCK1-like |
| cd14121 | 83-326 | STKc_ULK3 |
| cd14097 | 77-327 | STKc_STK33 |
| cd05585 | 83-337 | STKc_YPK1_like |
| cd05599 | 75-328 | STKc_NDR_like |
| cd14162 | 77-327 | STKc_TSSK4-like |
| cd06606 | 76-327 | STKc_MAPKKK |
| cd14071 | 77-326 | STKc_SIK |
| cd14092 | 82-337 | STKc_MSK_C |
| cd05582 | 83-337 | STKc_RSK_N |
| cd14093 | 111-326 | STKc_PhKG |
| cd05611 | 81-328 | STKc_Rim15_like |
| cd14188 | 80-324 | STKc_PLK2 |
| cd05590 | 81-337 | STKc_nPKC_eta |
| cd05595 | 83-337 | STKc_PKB_beta |
| cd14084 | 74-327 | STKc_Chk2 |
| cd14085 | 75-343 | STKc_CaMKIV |
| cd14166 | 83-341 | STKc_CaMKI_gamma |
| cd14004 | 76-327 | STKc_PASK |
| cd14075 | 77-327 | STKc_NIM1 |
| cd05614 | 76-337 | STKc_MSK2_N |
| cd14169 | 77-327 | STKc_CaMKI_beta |
| cd14165 | 77-326 | STKc_TSSK1_2-like |
| cd05593 | 73-316 | STKc_PKB_gamma |
| cd06609 | 75-332 | STKc_MST3_like |
| cd08530 | 76-325 | STKc_CNK2-like |
| cd14184 | 75-326 | STKc_DCKL2 |
| cd06627 | 77-327 | STKc_Cdc7_like |
| cd05613 | 76-316 | STKc_MSK1_N |
| cd14086 | 75-332 | STKc_CaMKII |
| cd14077 | 76-327 | STKc_Kin1_2 |
| cd05583 | 83-329 | STKc_MSK_N |
| cd05602 | 71-337 | STKc_SGK1 |
| cd05619 | 72-337 | STKc_nPKC_theta |
| cd14187 | 80-321 | STKc_PLK1 |
| cd14087 | 77-327 | STKc_PSKH1 |
| cd05592 | 83-337 | STKc_nPKC_theta_like |
| cd13999 | 83-315 | STKc_MAP3K-like |
| cd14120 | 83-325 | STKc_ULK1_2-like |
| cd05603 | 83-316 | STKc_SGK2 |
| cd05604 | 83-337 | STKc_SGK3 |
| cd05591 | 83-337 | STKc_nPKC_epsilon |
| cd05594 | 49-316 | STKc_PKB_alpha |
| cd08529 | 76-315 | STKc_FA2-like |
| cd05601 | 75-337 | STKc_CRIK |
| cd14076 | 79-327 | STKc_Kin4 |
| cd14168 | 77-331 | STKc_CaMKI_delta |
| cd14078 | 77-327 | STKc_MELK |
| cd08217 | 76-325 | STKc_Nek2 |
| cd14005 | 77-327 | STKc_PIM |
| cd14091 | 76-342 | STKc_RSK_C |
| cd14090 | 80-327 | STKc_Mnk |
| cd05598 | 75-337 | STKc_LATS |
| cd14106 | 64-327 | STKc_DRAK |
| cd05118 | 77-326 | STKc_CMGC |
| cd14181 | 116-326 | STKc_PhKG2 |
| cd14179 | 70-332 | STKc_MSK1_C |
| cd14105 | 75-327 | STKc_DAPK |
| cd05616 | 76-337 | STKc_cPKC_beta |
| cd14163 | 77-327 | STKc_TSSK3-like |
| cd05600 | 76-326 | STKc_Sid2p_like |
| cd14183 | 75-327 | STKc_DCKL1 |
| cd07829 | 77-326 | STKc_CDK_like |
| cd05587 | 83-337 | STKc_cPKC |
| cd14196 | 75-327 | STKc_DAPK2 |
| cd14114 | 75-327 | STKc_Twitchin_like |
| cd06614 | 83-325 | STKc_PAK |
| cd05615 | 74-337 | STKc_cPKC_alpha |
| cd05596 | 74-337 | STKc_ROCK |
| cd14119 | 83-327 | STKc_LKB1 |
| cd14665 | 77-326 | STKc_SnRK2-3 |
| cd13996 | 74-322 | STKc_EIF2AK |
| cd07833 | 83-326 | STKc_CDKL |
| cd13987 | 83-326 | STKc_SBK1 |
| cd14193 | 69-327 | STKc_MLCK4 |
| cd14089 | 76-326 | STKc_MAPKAPK |
| cd05610 | 73-325 | STKc_MASTL |
| cd14194 | 75-327 | STKc_DAPK1 |
| cd05586 | 83-337 | STKc_Sck1_like |
| cd13994 | 83-327 | STKc_HAL4_like |
| cd14201 | 73-327 | STKc_ULK2 |
| cd14088 | 75-327 | STKc_CaMK_like |
| cd14195 | 75-329 | STKc_DAPK3 |
| cd14202 | 77-327 | STKc_ULK1 |
| cd06632 | 80-327 | STKc_MEKK1_plant |
| cd05627 | 74-304 | STKc_NDR2 |
| cd06611 | 74-333 | STKc_SLK_like |
| cd14662 | 77-326 | STKc_SnRK2 |
| cd14174 | 83-328 | STKc_Mnk1 |
| cd05629 | 75-328 | STKc_NDR_like_fungal |
| cd06917 | 83-343 | STKc_NAK1_like |
| cd08220 | 76-325 | STKc_Nek8 |
| cd07840 | 77-326 | STKc_CDK9_like |
| cd05589 | 83-337 | STKc_PKN |
| cd14191 | 75-327 | STKc_MLCK1 |
| cd14190 | 72-327 | STKc_MLCK2 |
| cd05620 | 83-337 | STKc_nPKC_delta |
| cd07832 | 78-326 | STKc_CCRK |
| cd14118 | 83-327 | STKc_CAMKK |
| cd05609 | 76-326 | STKc_MAST |
| cd14173 | 113-327 | STKc_Mnk2 |
| cd14172 | 75-327 | STKc_MAPKAPK3 |
| cd06625 | 80-327 | STKc_MEKK3_like |
| cd06605 | 75-327 | PKc_MAPKK |
| cd14182 | 124-326 | STKc_PhKG1 |
| cd14164 | 77-327 | STKc_TSSK6-like |
| cd07841 | 77-340 | STKc_CDK7 |
| cd06612 | 75-327 | STKc_MST1_2 |
| cd14094 | 75-334 | STKc_CASK |
| cd05628 | 75-304 | STKc_NDR1 |
| cd05621 | 75-328 | STKc_ROCK2 |
| cd00192 | 81-315 | PTKc |
| cd14010 | 78-326 | STKc_ULK4 |
| cd14070 | 79-327 | STKc_HUNK |
| cd14137 | 77-325 | STKc_GSK3 |
| cd14175 | 75-341 | STKc_RSK1_C |
| cd14113 | 83-327 | STKc_Trio_C |
| cd08225 | 77-327 | STKc_Nek5 |
| cd13993 | 77-315 | STKc_Pat1_like |
| cd05622 | 75-337 | STKc_ROCK1 |
| cd06610 | 75-325 | STKc_OSR1_SPAK |
| cd06644 | 77-335 | STKc_STK10 |
| cd06613 | 76-272 | STKc_MAP4K3_like |
| cd14192 | 83-327 | STKc_MLCK3 |
| cd07835 | 83-326 | STKc_CDK1_CdkB_like |
| cd05618 | 74-337 | STKc_aPKC_iota |
| cd14176 | 69-327 | STKc_RSK2_C |
| cd07864 | 74-327 | STKc_CDK12 |
| cd14180 | 80-337 | STKc_MSK2_C |
| cd08224 | 76-321 | STKc_Nek6_7 |
| cd08218 | 83-315 | STKc_Nek1 |
| cd14046 | 68-320 | STKc_EIF2AK4_GCN2_rpt2 |
| cd05597 | 75-337 | STKc_DMPK_like |
| cd06648 | 83-328 | STKc_PAK_II |
| cd14133 | 77-327 | PKc_DYRK_like |
| cd14178 | 75-340 | STKc_RSK3_C |
| cd13990 | 83-326 | STKc_TLK |
| cd08528 | 76-323 | STKc_Nek10 |
| cd14082 | 83-326 | STKc_PKD |
| cd06643 | 75-327 | STKc_SLK |
| cd05617 | 74-337 | STKc_aPKC_zeta |
| cd14111 | 84-327 | STKc_SPEG_rpt2 |
| cd06608 | 75-327 | STKc_myosinIII_N_like |
| cd14115 | 83-326 | STKc_Kalirin_C |
| cd14066 | 83-287 | STKc_IRAK |
| cd06628 | 80-327 | STKc_Byr2_like |
| cd08219 | 76-315 | STKc_Nek3 |
| cd07839 | 83-326 | STKc_CDK5 |
| cd07860 | 77-326 | STKc_CDK2_3 |
| cd06626 | 80-327 | STKc_MEKK4 |
| cd05624 | 75-308 | STKc_MRCK_beta |
| cd07866 | 73-326 | STKc_BUR1 |
| cd06647 | 83-328 | STKc_PAK_I |
| cd14171 | 74-327 | STKc_MAPKAPK5 |
| cd07830 | 77-326 | STKc_MAK_like |
| cd14198 | 66-327 | STKc_DRAK2 |
| cd13985 | 81-322 | STKc_GAK_like |
| cd08222 | 77-327 | STKc_Nek11 |
| cd06640 | 83-333 | STKc_MST4 |
| cd06630 | 80-325 | STKc_MEKK1 |
| cd06620 | 75-317 | PKc_Byr1_like |
| cd13986 | 77-324 | STKc_16 |
| cd05577 | 83-337 | STKc_GRK |
| cd08221 | 81-320 | STKc_Nek9 |
| cd07848 | 75-325 | STKc_CDKL5 |
| cd14177 | 75-327 | STKc_RSK4_C |
| cd06659 | 83-337 | STKc_PAK6 |
| cd14170 | 75-342 | STKc_MAPKAPK2 |
| cd14058 | 83-315 | STKc_TAK1 |
| cd06629 | 80-327 | STKc_Bck1_like |
| cd05623 | 75-308 | STKc_MRCK_alpha |
| cd07846 | 83-287 | STKc_CDKL2_3 |
| cd05630 | 81-334 | STKc_GRK6 |
| cd14199 | 74-327 | STKc_CaMKK2 |
| cd06621 | 78-333 | PKc_Pek1_like |
| cd07836 | 83-326 | STKc_Pho85 |
| cd07845 | 73-328 | STKc_CDK10 |
| cd13989 | 83-273 | STKc_IKK |
| cd06641 | 83-333 | STKc_MST3 |
| cd05626 | 81-329 | STKc_LATS2 |
| cd14104 | 77-334 | STKc_Titin |
| cd13978 | 83-278 | STKc_RIP |
| cd05588 | 81-337 | STKc_aPKC |
| cd14101 | 77-328 | STKc_PIM2 |
| cd07873 | 83-335 | STKc_PCTAIRE1 |
| cd14132 | 73-325 | STKc_CK2_alpha |
| cd07852 | 77-329 | STKc_MAPK15-like |
| cd14048 | 76-324 | STKc_EIF2AK3_PERK |
| cd05625 | 81-329 | STKc_LATS1 |
| cd06655 | 83-328 | STKc_PAK2 |
| cd06642 | 83-273 | STKc_STK25 |
| cd14068 | 83-321 | STKc_LRRK2 |
| cd07838 | 77-327 | STKc_CDK4_6_like |
| cd07871 | 83-288 | STKc_PCTAIRE3 |
| cd07851 | 75-328 | STKc_p38 |
| cd14131 | 76-325 | PKc_Mps1 |
| cd07847 | 83-326 | STKc_CDKL1_4 |
| cd14038 | 83-273 | STKc_IKK_beta |
| cd06615 | 75-328 | PKc_MEK |
| cd07861 | 76-326 | STKc_CDK1_euk |
| cd14102 | 77-327 | STKc_PIM3 |
| cd14039 | 83-273 | STKc_IKK_alpha |
| cd14200 | 77-327 | STKc_CaMKK1 |
| cd13995 | 81-324 | STKc_MAP3K8 |
| cd13997 | 76-325 | PKc_Wee1_like |
| cd14197 | 80-327 | STKc_DRAK1 |
| cd14107 | 77-326 | STKc_obscurin_rpt1 |
| cd05631 | 81-334 | STKc_GRK4 |
| cd07834 | 77-326 | STKc_MAPK |
| cd06656 | 83-328 | STKc_PAK3 |
| cd05608 | 76-337 | STKc_GRK1 |
| cd06650 | 75-319 | PKc_MEK1 |
| cd07865 | 83-326 | STKc_CDK9 |
| cd06658 | 83-340 | STKc_PAK5 |
| cd06653 | 76-327 | STKc_MEKK3_like_u1 |
| cd06654 | 83-273 | STKc_PAK1 |
| cd14158 | 68-274 | STKc_IRAK4 |
| cd06622 | 75-332 | PKc_PBS2_like |
| cd07843 | 73-326 | STKc_CDC2L1 |
| cd14060 | 84-321 | STKc_MLTK |
| cd06652 | 76-308 | STKc_MEKK2 |
| cd14109 | 75-327 | PK_Unc-89_rpt1 |
| cd08228 | 74-279 | STKc_Nek6 |
| cd08223 | 76-327 | STKc_Nek4 |
| cd05047 | 83-322 | PTKc_Tie |
| cd06638 | 75-273 | STKc_myosinIIIA_N |
| cd06617 | 75-327 | PKc_MKK3_6 |
| cd14059 | 83-324 | STKc_MAP3K12_13 |
| cd07879 | 82-326 | STKc_p38delta |
| cd06639 | 75-328 | STKc_myosinIIIB_N |
| cd05605 | 77-335 | STKc_GRK4_like |
| cd05632 | 75-328 | STKc_GRK5 |
| cd05607 | 81-316 | STKc_GRK7 |
| cd07831 | 83-326 | STKc_MOK |
| cd14047 | 76-315 | STKc_EIF2AK2_PKR |
| cd06624 | 83-327 | STKc_ASK |
| cd05633 | 71-316 | STKc_GRK3 |
| cd06637 | 77-334 | STKc_TNIK |
| cd06657 | 83-340 | STKc_PAK4 |
| cd14100 | 77-327 | STKc_PIM1 |
| cd06636 | 77-273 | STKc_MAP4K4_6_N |
| cd06607 | 77-328 | STKc_TAO |
| cd13983 | 83-326 | STKc_WNK |
| cd14112 | 75-327 | STKc_Unc-89_rpt2 |
| cd08229 | 73-273 | STKc_Nek7 |
| cd07856 | 81-327 | STKc_Sty1_Hog1 |
| cd05089 | 75-322 | PTKc_Tie1 |
| cd06645 | 68-272 | STKc_MAP4K3 |
| cd07872 | 83-338 | STKc_PCTAIRE2 |
| cd14037 | 78-322 | STKc_NAK_like |
| cd05056 | 75-315 | PTKc_FAK |
| cd13988 | 83-273 | STKc_TBK1 |
| cd07844 | 82-326 | STKc_PCTAIRE_like |
| cd07870 | 83-326 | STKc_PFTAIRE2 |
| cd14110 | 85-327 | STKc_obscurin_rpt2 |
| cd13979 | 82-315 | STKc_Mos |
| cd06651 | 80-321 | STKc_MEKK3 |
| cd14041 | 71-344 | STKc_TLK2 |
| cd14052 | 76-325 | PTKc_Wee1_fungi |
| cd07880 | 81-288 | STKc_p38gamma |
| cd05148 | 76-315 | PTKc_Srm_Brk |
| cd07877 | 82-326 | STKc_p38alpha |
| cd06633 | 83-311 | STKc_TAO3 |
| cd06619 | 83-328 | PKc_MKK5 |
| cd14040 | 83-333 | STKc_TLK1 |
| cd07878 | 81-326 | STKc_p38beta |
| cd14016 | 77-239 | STKc_CK1 |
| cd05038 | 81-317 | PTKc_Jak_rpt2 |
| cd14221 | 83-267 | STKc_LIMK1 |
| cd14154 | 83-263 | STKc_LIMK |
| cd14222 | 83-267 | STKc_LIMK2 |
| cd14065 | 83-267 | PKc_LIMK_like |
| cd14000 | 83-319 | STKc_LRRK |
| cd06646 | 66-272 | STKc_MAP4K5 |
| cd14150 | 83-321 | STKc_A-Raf |
| cd07863 | 83-326 | STKc_CDK4 |
| cd06631 | 80-327 | STKc_YSK4 |
| cd14159 | 83-282 | STKc_IRAK1 |
| cd14664 | 83-276 | STK_BAK1_like |
| cd05046 | 83-315 | PTK_CCK4 |
| cd14012 | 109-325 | PK_eIF2AK_GCN2_rpt1 |
| cd06635 | 65-273 | STKc_TAO1 |
| cd05059 | 74-315 | PTKc_Tec_like |
| cd05101 | 72-283 | PTKc_FGFR2 |
| cd14108 | 75-326 | STKc_SPEG_rpt1 |
| cd14223 | 76-316 | STKc_GRK2 |
| cd06634 | 81-273 | STKc_TAO2 |
| cd14146 | 83-323 | STKc_MLK4 |
| cd05098 | 75-283 | PTKc_FGFR1 |
| cd05041 | 83-315 | PTKc_Fes_like |
| cd06649 | 75-272 | PKc_MEK2 |
| cd14056 | 82-321 | STKc_TGFbR_I |
| cd07862 | 83-288 | STKc_CDK6 |
| cd05606 | 83-328 | STKc_beta_ARK |
| cd07849 | 75-327 | STKc_ERK1_2_like |
| cd07842 | 77-273 | STKc_CDK8_like |
| cd05085 | 80-321 | PTKc_Fer |
| cd14061 | 83-274 | STKc_MLK |
| cd05088 | 75-321 | PTKc_Tie2 |
| cd14205 | 83-274 | PTKc_Jak2_rpt2 |
| cd05092 | 71-323 | PTKc_TrkA |
| cd14022 | 134-326 | PK_TRB2 |
| cd05099 | 72-283 | PTKc_FGFR4 |
| cd14049 | 78-315 | STKc_EIF2AK1_HRI |
| cd07867 | 75-294 | STKc_CDC2L6 |
| cd05114 | 81-285 | PTKc_Tec_Rlk |
| cd05115 | 71-321 | PTKc_Zap-70 |
| cd05036 | 81-321 | PTKc_ALK_LTK |
| cd05053 | 72-271 | PTKc_FGFR |
| cd05032 | 75-321 | PTKc_InsR_like |
| cd05116 | 83-321 | PTKc_Syk |
| cd05112 | 75-315 | PTKc_Itk |
| cd14210 | 71-327 | PKc_DYRK |
| cd05074 | 77-315 | PTKc_Tyro3 |
| cd05049 | 71-316 | PTKc_Trk |
| cd05034 | 81-315 | PTKc_Src_like |
| cd05093 | 71-321 | PTKc_TrkB |
| cd07869 | 75-273 | STKc_PFTAIRE1 |
| cd14036 | 79-321 | STKc_GAK |
| cd05057 | 77-275 | PTKc_EGFR_like |
| cd14145 | 83-321 | STKc_MLK1 |
| cd07868 | 75-294 | STKc_CDK8 |
| cd14147 | 83-321 | STKc_MLK3 |
| cd07855 | 72-326 | STKc_ERK5 |
| cd14031 | 83-326 | STKc_WNK3 |
| cd14151 | 75-323 | STKc_B-Raf |
| cd07837 | 75-326 | STKc_CdkB_plant |
| cd14144 | 81-316 | STKc_BMPR1 |
| cd05060 | 83-322 | PTKc_Syk_like |
| cd14027 | 83-315 | STKc_RIP1 |
| cd13982 | 123-325 | STKc_IRE1 |
| cd05113 | 81-287 | PTKc_Btk_Bmx |
| cd14134 | 77-326 | PKc_CLK |
| cd05084 | 80-315 | PTKc_Fes |
| cd05100 | 72-283 | PTKc_FGFR3 |
| cd05035 | 77-315 | PTKc_TAM |
| cd06618 | 72-328 | PKc_MKK7 |
| cd05081 | 83-267 | PTKc_Jak3_rpt2 |
| cd14033 | 76-324 | STKc_WNK4 |
| cd14064 | 83-323 | PKc_TNNI3K |
| cd07850 | 81-328 | STKc_JNK |
| cd05094 | 71-321 | PTKc_TrkC |
| cd07876 | 81-327 | STKc_JNK2 |
| cd14142 | 83-321 | STKc_ACVR1_ALK1 |
| cd14024 | 134-327 | PK_TRB3 |
| cd05039 | 76-321 | PTKc_Csk_like |
| cd14032 | 83-326 | STKc_WNK2_like |
| cd05072 | 75-315 | PTKc_Lyn |
| cd14063 | 76-273 | PK_KSR |
| cd14148 | 83-273 | STKc_MLK2 |
| cd14228 | 75-318 | STKc_HIPK1 |
| cd14050 | 77-325 | PKc_Myt1 |
| cd13968 | 83-220 | PKc_like |
| cd14023 | 118-326 | PK_TRB1 |
| cd07854 | 81-331 | STKc_MAPK4_6 |
| cd14229 | 77-285 | STKc_HIPK3 |
| cd05050 | 75-321 | PTKc_Musk |
| cd14227 | 75-318 | STKc_HIPK2 |
| cd14062 | 83-321 | STKc_Raf |
| cd13998 | 84-266 | STKc_TGFbR-like |
| cd14011 | 91-328 | PK_SCY1_like |
| cd07857 | 77-327 | STKc_MPK1 |
| cd07875 | 81-327 | STKc_JNK1 |
| cd14156 | 83-267 | PKc_LIMK_like_unk |
| cd14211 | 77-287 | STKc_HIPK |
| cd05045 | 76-271 | PTKc_RET |
| cd05040 | 83-315 | PTKc_Ack_like |
| cd14149 | 83-321 | STKc_C-Raf |
| cd05044 | 83-321 | PTKc_c-ros |
| cd05073 | 77-315 | PTKc_Hck |
| cd07874 | 81-327 | STKc_JNK3 |
| cd05075 | 79-315 | PTKc_Axl |
| cd05063 | 83-308 | PTKc_EphR_A2 |
| cd05067 | 75-315 | PTKc_Lck_Blk |
| cd07859 | 77-339 | STKc_TDY_MAPK |
| cd14053 | 85-267 | STKc_ACVR2 |
| cd05079 | 81-315 | PTKc_Jak1_rpt2 |
| cd14030 | 76-331 | STKc_WNK1 |
| cd05090 | 78-315 | PTKc_Ror1 |
| cd05082 | 76-315 | PTKc_Csk |
| cd13991 | 70-257 | STKc_NIK |
| cd14225 | 77-273 | PKc_DYRK4 |
| cd05033 | 74-321 | PTKc_EphR |
| cd06616 | 72-273 | PKc_MKK4 |
| cd05066 | 79-310 | PTKc_EphR_A |
| cd14224 | 77-273 | PKc_DYRK2_3 |
| cd14212 | 83-285 | PKc_YAK1 |
| cd13974 | 92-321 | STKc_SHIK |
| cd14019 | 75-325 | STKc_Cdc7 |
| cd05052 | 77-315 | PTKc_Abl |
| cd14160 | 83-269 | PK_IRAK3 |
| cd05048 | 71-285 | PTKc_Ror |
| cd07858 | 77-326 | STKc_TEY_MAPK |
| cd07853 | 76-328 | STKc_NLK |
| cd08216 | 78-273 | PK_STRAD |
| cd13976 | 128-326 | PK_TRB |
| cd05576 | 135-326 | STKc_RPK118_like |
| cd14220 | 81-321 | STKc_BMPR1a |
| cd05054 | 72-287 | PTKc_VEGFR |
| cd05080 | 81-275 | PTKc_Tyk2_rpt2 |
| cd14054 | 83-267 | STKc_BMPR2_AMHR2 |
| cd14155 | 83-267 | PKc_TESK |
| cd14026 | 81-315 | STKc_RIP2 |
| cd14207 | 72-315 | PTKc_VEGFR1 |
| cd05062 | 81-315 | PTKc_IGF-1R |
| cd05065 | 83-308 | PTKc_EphR_B |
| cd05058 | 81-273 | PTKc_Met_Ron |
| cd14018 | 134-323 | STKc_PINK1 |
| cd14025 | 81-288 | STKc_RIP4_like |
| cd05061 | 81-315 | PTKc_InsR |
| cd14204 | 79-324 | PTKc_Mer |
| cd14153 | 78-275 | PK_KSR2 |
| cd05070 | 75-315 | PTKc_Fyn |
| cd13977 | 77-316 | STKc_PDIK1L |
| cd14140 | 85-267 | STKc_ACVR2b |
| cd14157 | 85-271 | STKc_IRAK2 |
| cd05055 | 72-322 | PTKc_PDGFR |
| cd05051 | 78-267 | PTKc_DDR |
| cd13975 | 78-269 | PKc_Dusty |
| cd05103 | 72-287 | PTKc_VEGFR2 |
| cd14055 | 83-249 | STKc_TGFbR2_like |
| cd05068 | 75-315 | PTKc_Frk_like |
| cd14219 | 83-266 | STKc_BMPR1b |
| cd14135 | 77-293 | STKc_PRP4 |
| cd14067 | 121-272 | STKc_LRRK1 |
| cd14203 | 81-315 | PTKc_Src_Fyn_like |
| cd05091 | 83-267 | PTKc_Ror2 |
| cd05069 | 83-315 | PTKc_Yes |
| cd05087 | 81-293 | PTKc_Aatyk1 |
| smart00220 | 77-327 | S_TKc |
| pfam00069 | 77-327 | Pkinase |
| PTZ00263 | 69-337 | PTZ00263 |
| COG0515 | 76-340 | SPS1 |
| PHA03390 | 76-316 | pk1 |
| PTZ00426 | 75-326 | PTZ00426 |
| smart00219 | 78-315 | TyrKc |
| smart00221 | 78-315 | STYKc |
| pfam07714 | 77-315 | Pkinase_Tyr |
| PLN00034 | 60-344 | PLN00034 |
| PLN00009 | 74-328 | PLN00009 |
| PTZ00267 | 123-315 | PTZ00267 |
| PTZ00266 | 74-315 | PTZ00266 |
| PTZ00024 | 79-326 | PTZ00024 |
| PTZ00036 | 77-326 | PTZ00036 |
| PTZ00283 | 79-315 | PTZ00283 |
| TIGR03903 | 103-320 | TOMM_kin_cyc |
| PRK13184 | 77-315 | pknD |
| PHA03209 | 77-267 | PHA03209 |
| PHA03207 | 77-293 | PHA03207 |
| PHA02988 | 85-315 | PHA02988 |
| PHA03210 | 121-267 | PHA03210 |
| PHA03212 | 125-274 | PHA03212 |
| PHA03211 | 122-283 | PHA03211 |
| PLN03225 | 22-205 | PLN03225 |
Ontology Information
| HPRD ID | 8307 |
|---|---|
| Molecular Class | Serine/threonine kinase |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.