Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| GCNT3 | 9245 | glucosaminyl (N-acetyl) transferase 3, mucin type | 15 | C2GnT-M, C2/4GnT, C2GnT2 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25466507 | 2015 | Cell line : - Source : La Paz University Hospital (Madrid, Spain). Sample Type : Formalin-fixed, paraffin-embedded tissue No. of Sample : - Stage : Stage II | real time RT-PCR,Univariate and Multivariate Cox regression analyses | Down-regulation | - | Low GCNT3 expression is a promising prognostic biomarker for colon cancer that could be used to identify early-stage colon cancer patients at high risk of relapse. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Glucosaminyl (N-acetyl) transferase and xylosyltransferase family |
| Description | This gene encodes a member of the N-acetylglucosaminyltransferase family. The encoded protein is a beta-6-N-acetylglucosamine-transferase that catalyzes the formation of core 2 and core 4 O-glycans on mucin-type glycoproteins.[provided by RefSeq, Apr 2009] |
| Chromosome | 15 |
| Location | 15q22 |
| Start | 59903982 |
| End | 59912210 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 8229 |
| OMIM ID | 606836 |
| HGNC ID | HGNC:4205 |
| Unigene ID | Hs.194710 |
| Ensembl ID | ENSG00000140297 |
| PharmGKB ID | PA28620 |
Protein Information
| Protein ID | NP_004742.1 |
|---|---|
| Protein Name | glucosaminyl (N-acetyl) transferase 3, mucin type |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 438 |
| Uniprot ID | Q8N0X7 |
| Ensembl Protein ID | ENSP00000347314 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Metabolic pathways | hsa01100 |
| Mucin type O-Glycan biosynthesis | hsa00512 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam02485 | 133-401 | Branch |
| cl12266 | 133-401 | Branch superfamily |
| PLN03183 | 143-310 | PLN03183 |
Ontology Information
| HPRD ID | 11066 |
|---|---|
| Molecular Class | Enzyme: Glucosaminyltransferase |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.