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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 9626469 | 1998 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 82 Stage : - | real time RT-PCR | Up-regulation | - | Study of MRP1/CD9 expression may be useful for predicting prognosis of patients with colorectal cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | CD molecules, "Tetraspanins" |
| Description | This gene encodes a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Tetraspanins are cell surface glycoproteins with four transmembrane domains that form multimeric complexes with other cell surface proteins. The encoded protein functions in many cellular processes including differentiation, adhesion, and signal transduction, and expression of this gene plays a critical role in the suppression of cancer cell motility and metastasis. [provided by RefSeq, Jan 2011] |
| Chromosome | 12 |
| Location | 12p13 |
| Start | 6309482 |
| End | 6347437 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 37956 |
| OMIM ID | 143030 |
| HGNC ID | HGNC:1709 |
| Unigene ID | Hs.114286 |
| Ensembl ID | ENSG00000010278 |
| PharmGKB ID | PA26247 |
mRNA Information
| mRNA ID | XM_011521040.1 |
|---|---|
| Exon | join(1..229,25583..25691,32789..32886,33569..33643, 35386..35484,35633..35722,36349..36432,37920..38423) | mRNA Sequence | Download Select all |
| Length | 1288 |
Protein Information
| Protein ID | XP_011519342.1 |
|---|---|
| Protein Name | CD9 molecule |
| Molecular Wt. (Da) | 17633 |
| Protein Sequence | Download Select all |
| Length | 159 |
| Uniprot ID | Q99519 |
| Ensembl Protein ID | ENSP00000229725 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 930 | CD19 | 113 | NP_001761.3 | in vivo | 9804823 |
| 966 | CD59 | 117 | NP_000602.1 | in vitro | 1377690 |
| 1839 | HBEGF | 526 | NP_001936.1 | in vivo;yeast 2-hybrid | 193 910 111 735 113 000 000 000 000 000 |
| 3673 | ITGA2 | 1893 | NP_002194.2 | in vivo | 98 129 069 813 091 |
| 3678 | ITGA5 | 627 | NP_002196.2 | in vivo | 10065872 |
| 3688 | ITGB1 | 628 | NP_391987.1 | in vivo | 98 129 069 813 091 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Hematopoietic cell lineage | hsa04640 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd03152 | 111-193 | CD9_LEL |
| cl02781 | 111-193 | tetraspanin_LEL superfamily |
| cd03151 | 114-192 | CD81_like_LEL |
| pfam00335 | 9-221 | Tetraspannin |
Ontology Information
| HPRD ID | 1203 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | GTPase activator activity (GO:0005096) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.