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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24812030 | 2014 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | Immunohistochemical analysis, | Up-regulation | - | High-temperature requirement A3 (HTRA3) and follistatin (FST) were collectively overexpressed in desmoplastic cocultures of colorectal cancer (CRC) |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | - |
| Chromosome | 4 |
| Location | 4p16.1 |
| Start | 8271487 |
| End | 8308838 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 37352 |
| OMIM ID | 608785 |
| HGNC ID | HGNC:30406 |
| Unigene ID | Hs.479119 |
| Ensembl ID | ENSG00000170801 |
| PharmGKB ID | PA134908281 |
Protein Information
| Protein ID | NP_001284488.1 |
|---|---|
| Protein Name | HtrA serine peptidase 3 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 453 |
| Uniprot ID | Q96B33 |
| Ensembl Protein ID | ENSP00000428780 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00987 | 355-440 | PDZ_serine_protease |
| cl00117 | 355-440 | PDZ superfamily |
| cd00104 | 89-126 | KAZAL_FS |
| cl00097 | 89-126 | KAZAL_FS superfamily |
| pfam13365 | 175-319 | Trypsin_2 |
| cl21584 | 175-319 | Tryp_SPc superfamily |
| smart00121 | 23-79 | IB |
| cl02472 | 23-79 | IGFBP superfamily |
| pfam13180 | 384-447 | PDZ_2 |
| smart00228 | 380-440 | PDZ |
| cd00989 | 387-449 | PDZ_metalloprotease |
| cd00992 | 381-426 | PDZ_signaling |
| cd00136 | 385-420 | PDZ |
| pfam00219 | 23-76 | IGFBP |
| pfam00595 | 383-423 | PDZ |
| pfam07648 | 89-126 | Kazal_2 |
| cd00988 | 378-439 | PDZ_CTP_protease |
| smart00280 | 89-126 | KAZAL |
| pfam00050 | 89-126 | Kazal_1 |
| COG3591 | 185-352 | eMpr |
| cd00991 | 381-445 | PDZ_archaeal_metalloprotease |
| cd01327 | 89-126 | KAZAL_PSTI |
| cd00986 | 385-447 | PDZ_LON_protease |
| TIGR02037 | 143-440 | degP_htrA_DO |
| COG0265 | 125-440 | DegQ |
| PRK10898 | 147-453 | PRK10898 |
| PRK10139 | 143-431 | PRK10139 |
| TIGR02038 | 144-431 | protease_degS |
| PRK10942 | 175-426 | PRK10942 |
| pfam00089 | 177-341 | Trypsin |
| PRK10779 | 380-451 | PRK10779 |
| COG0793 | 370-442 | CtpA |
| TIGR03900 | 386-452 | prc_long_Delta |
| TIGR02860 | 395-450 | spore_IV_B |
| TIGR00054 | 314-450 | TIGR00054 |
Ontology Information
| HPRD ID | 6565 |
|---|---|
| Molecular Class | Serine protease |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.