CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
AIM2	9447	absent in melanoma 2	1	PYHIN4

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
24729378	2014	Cell line : - Source : - Sample Type : CRC tumor, normal tissue and stool sample No. of Sample : 476 matched tissue pairs (colorectal tumor and adjacent normal colon epithelium) Stage : -	Tissue microarray	Down-regulation	-	Lack of AIM2 expression may be used as a biomarker for the identification of colorectal cancer patients with poor prognosis.

Gene Details

Chromosome 1 - NC_000001.11 (159062479..159076895, complement)
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Gene Type	protein coding
Gene Family
Description	AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.
Chromosome	1
Location	1q22
Start	159062479
End	159076895
Strand	-
Gene Sequence	>gi\|568815597:c159076895-159062479 Homo sapiens chromosome 1, GRCh38.p2 Primary Assembly ATTTTCTTCTGTGGCTGCTAGTGAGAACCCAAACCAGCTCAGCCAATTAGAGCTCCAGTTGTCACTCCTA CCCACACTGGGCCTGGGGGTGAAGGGAAGTGTTTATTAGGGGTACATGTGAAGCCGTCCAGAAGTGTCAG AGTCTTTGTAGCTTTGAAAGTCACCTAGGTTATTTGGGCATGCTCTCCTGAGTCCTCTGCTAGTTAAGCT CTCTGAAAAGAAGGTGGCAGACCCGGTTTGCTGATCGCCCCAGGGATCAGGAGGTAAGCACCATAGAGGA GCTGGGTTAGAGACGAGAGACTTAACCGTTTCTCTGCTGAAAAAGACAACTGAGGAAAGGCCAGCCATGC TGTGCACACCTCTGAGAACCTGAACCTGCAAACATGGACATCAGCTCTGAAAGGATGGGTTCATTTCTCT TTTATTCACTTTAGCCATGTCCTCTGGTGTCTCTGAGCTGGTGTTCCTTAAGCTTCGGCTTCCTTTGGGG TTTGTCTATCAGCCTATTTGTAAGGCTGACTTTTATGCCAATAGCAAATACAAGCATTTTTTAAGTTAAC AGATATTATGAAGTAAAATGCAAGTTTTTCATTTATAAGGCAACATAACTTCAGAGAAAAAACTGAGTCA ATCACATAAAATGTGATTAAAATGTGATTGTTATTATATAAGAGGGTTATAGGAAGATTAGCTTCTTATG GACAAGTAGAAAAGTAGGAATCATCCAAGCTGATTGTCACAGTAGATATTCAACAAAGGTAGTGTCCTTC CTTGCTTTCATCAGTAGGATGGGGGCATTTGGATGGCTTTATCATTGCAAATATTTTTAATGTATTCCTT ATTTTGAAAATGGTCCTGATAATAGTTTTAATTTTCACTCATGAACTCTACATGTATAAGTAGAGTTTCT CCAGCGCTTACCAACATATAGGAAAAAACATTATAAGGCCATTAACAGTGATAGTTTAGAATTTATTAAC ATTGACTCTACTGATGGGGGTATTCAAGCTTCCCTAAAATTCACAATCAGTTATTTTCAGCTCATAAACA TCTTTTCCTGTTCTTTGGCTTATTTCTTCCACTTTATATGTTGCTGCTCTGGAAGTCATTAATTGCTAAT AATGTCAAACATCTTTTTTATGTTTATTGGATATTTGAGCAAATTGCTCATTCACATCTTTTGCACACTT TTCAAATAGACTGTTGTTTTCTTATTGATACATGGTTCTCCATGTATTCCAAAAGCAAAACCTCTATTAG CTCTCTCTCTCTCTCTCTCTCTCTATATATATATATATAGCAGGTATAGCCATATATATATGTGTGTGTG TGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATTGCAGGTATCTGCCCAGTTTTTGCCTTGTATAATCAC TTTGTTTAGTGTGTGTGTGTGCACGGATGTGTGTGTTTCCTACAAAGAAATTGAGAATATGCATGCAATC ACATTTGACAAATTTTTTTTTTCTGGCTTGTCCTTTTTGTGCCTTATTTAAGGAACCTCCTTCTACTTCA ATGTATTGAGAAATTCTGTGTTTTATTCAACATCATTACTATTCTATTTAGATAATTAATCCAACCAGAT ATATATTTTGTGTATGATATAAGAGAAAGGCTGAATATATCATTCCCTGTGTATTGTCATTTGTCTGAAC ACTTTTTATAGTTGGCCATTCTTTCCTTGTGATTTTTAATGCCACTTTGATTATATACCAAGCTTTAATT TACATGTGGTCCTGTTTCCACACTCTATTTATTAGTTCATTTTTTTCTACGCCACTGCCATACTGATTTA ATAATTATACATTTGTAGTAAGTATTGATACCTAGTAGTAGGGATAGTACATCCTGATAAACATATTCAA CTTGTTTTGCAGGTTTTTGTCTTTATTTTTTTCATTTAGGTTTTAGGATCATTCTGATAAATTCTATGAA AAACCCTTTGAGATTTTGGATAGGAGTTTATAGATTAATTTGACAACACTGCTGTCTTCATTTTATCAAA TCTTCCCATTTAAAATATCAGACATACACCCACTTAAGTAGGTCCTTTAAATCTCCCAATAAAGTTTTAT AAGTTTCCCTTTAAAACTCTTAAATATATTGTATTCGATGTTCTTATGTACTTTGTAGTTTTGTTGCTAT TGGAAATTACTTTTTTTATGTAATTTTTTTCTCTCTTGGAGTGGTACTAAAATAAAGGAATGCATTTCTG TATATTAATCTTATAGTTATAAACTGTTGAATTATTATTTATAATGTTTTGTGTATTATTTTGGATACTA TACATAAACAACTATATTACTACAACGTGATTTTGGCAACAAGTTACAAAAATAGGTTGATGGACAGAAT AAAGAATCCAGAAATAGACTCACTCATATTTGGACAACTGATTTTTGCAAAGGTAAAAAAAAAAATCATT AAAAATGACAGTCTTTTTAACATATGATTCTGGGAAAATTCATATTCATATGAAAAATAAATGAACTTTG AATCATCACTTATATCATATACAAATTAACTCAAAGCAGTACATACAGCCAAATGTGAAATGATCAAACC GTAAAATTCTTACAGGAAGACATAAAATCTTCTAATCTTGAGATTGGAAAAGATTTCTTAAATAAGACAC TGAAAGCATGATCCATGAAAGAACAGATTGATTAATTGCACTTCATCAGGTATATGTATATGCCAAAATT TATCAGATTGTATACTTCCAGTGTATGCACCGTGTTGTATGCCAGTTATGCCTCGATAAATCTATTTTAA AAATAACAGGAAAATGTATCCTGTTTCCTTTTTGTTGTTGTTGTTGTTGTTGTTTTGAGATGAAGTTTCG CTCCTGTTGCCCAGGCTGGAGTGCAATGGCGCGATCTTGGCTCACTGCAACCTCCACCTCCCAGGTTCAA ATAATTCTCCTGCCTCAGCCTCCTGAGTAGTTGGGATTACAGGCGCCCACCACCATGCTCGGCTAATTTT TGTACTTTTAGTAGAGATGGGGTTTTGCCATATTGGCCAGTCTGGTCTCAAACTCCTGACCGCAGGTGAT CCGCCCACCTTGGCCTTCCAAAGTGCTGGGATTATTACAGGCGTGAGCTACCGCGCCCAGCTAATGTATC TTGTTTTCTGAGAATTCCAGAGGTGTTGTATACTTTCTGAAGATGTCTTTCCCAGGAGTAGTGATCACCT TGCTTAAGAAGTTCTTACCTATGTCCTACTCAAATCTCTTTTACTACTGCAAATATTTTATTTTTCTTTA AAAAATATTAATAGCTCACCTTGCTTTATTTTGAATGTAGAATCACTTTTGGTGGTGTAATCTTACATGT TTTGGATTCCTTATAGGCTGATCCCAAAGTTGTCAGATGGAGAGTAAATACAAGGAGATACTCTTGCTAA CAGGCCTGGATAACATCACTGATGAGGAACTGGATAGGTTTAAGTTCTTTCTTTCAGACGAGTTTAATAT TGCCACAGGCAAACTACATACTGCAAACAGAATACAAGTAGCTACCTTGATGATTCAAAATGCTGGGGCG GTGTCTGCAGTGATGAAGACCATTCGTATTTTTCAGAAGTTGAATTATATGCTTTTGGCAAAACGTCTTC AGGAGGAGAAGGAGAAAGGTAATGTGGGAGTTCCACACCTGCCCCGTCCCTTTTTCTGCCAAGCCTGGGC CTTTCCTTTCATGGCATCCCTGGGATATGACCCCCAGTGCACATTGTTGGAATTTGTTTGCTAACTTAGT GCACCTGTCTCTTTGCCCCCTTTTACTGAGAATCGCTTCTAGGAAGTGTTTGTTACAAATTCCACAAATC CATTCCAGCCTTTGTTTGCATCTCTTCTTCCAGCCTTAGGGTTACCACTTCCATTTAACATCTTTTCTCC TTGCCCATCTTTGTCTCCAGTTCAGTTGCAGTGAATATGGACGTAGAATTTCAAAGTTAACTTCTCCCAA CTCCATTTACACAGTATGTAATGCTGTCACATTCTACTGAAGTCTTGAAAGTATAAATTATTGCATTGGA AAACTGTAAACCAGGATATTGAGCACCTTTTTTCCTTCACACAGTCTGTCTATTCCTCTCCTTGTCCCCA GCTTTCTGTGGTCCCAGACTATCCTTCTTTAGGCGATGATCTCCTCCTTCTTCAGAAGGGAGGGAGAATC CACCTTCAGGGATTTTCTTTCCTCTCTATCTCCAGTACAGGTGACAGTATAAATTACCCACAACACAAAG ATTTTTTTTACATTATTCAATAAATCACTCATCTCCATCTGAATTATCTACATTTAGTTTAAATTCCTGA TTTTGTTTACTAAGAACAATTGATATGTCCCAGCTTTATGTCTGAAGAACAAAAAGGAGCTAACAGAGGA GCATATCACTCAAGGACTCTCCAAAATGAAAGTCTCCAAATGCAACAGTTTTAGGATTCAAAGTACAACA GTAGCAGCAAAAATTATAATAGCTTTTAGTAGCATTTGTGGGTGTACAACAAGGGTGACATGGCTTCTCA CACATGAGTTATAGGAAGGCTAAATGAAGCCACATAAGTGATACTATGTACATTCATAATTCTATACAGA TATAAACTGTTAGGTAGTTTCTAAGGCACTAAAGAGAAAGGAGTGGTGGTTTTCCCAGGCTTTAAGTTAG AAGGTGTAGTTCTTAGAGATGGCCCTTAGATGGCAGTAACTACACATGTTACTTCCAAGTAACCAACCAA AACATTGCCCTGTGTTTTTCTTATCTGGGATGAGCCAGGAATCTAGGCATATTGGCAAACATAGGCTGAG ATATTTAGAAATATCTTTTATTTTGGTAATAAATCAAGAATTAATTCTTCTCTTTGACCAGGATAGAACA AAATTTCCCCTTCTACAATCTTCTCCCCATTTTGCTATTCTAATGATTCTGGGATTTTGTTATTCTGCTT AGCTAAAAAAGATCCAGTTTGGGACTAGCTTGGAAACTCAGGAGTAGATTATCCAAGGACTCTCCCAAAT GAGAGTCTCCAAATGTAACAGTTGTAGGATTCAAAGTATGCTTTTGGGCCAGGCGCAGTGGCTCACGCCT TTAATCCCAGCACTTTGGGAGGCCAAGGCGGGTGGATCACTTGAGTTCAGGAGTTCGAGATCAGCCTGGC CAACATAGTGAAACTTTGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCGGGCATCTGTAAT GCCAGCTACTTGGGAGGCTGAGGCACGAGAATCACTTGAACCTGGGAGGGAGAGGTTGCAGTGAGCTGAG ATCACACCTCTGCACTCCTGCCTGGGCAACAACAGTGAGACCCTGTCTCAAACAACAACAACAACAAAAC ACAAAGTATGCTTCTTGCATGCTATACAAGAAGGCAGTTAAGTTCCTTCATAGCTCTAAAATTCTATCCA CGGACATACTTAGGCCGCTTTTGAATGTAGGAAATTTTTGTGTGTCCATGCTATTTCTATTATTTTAGGA AAACAGTTTTTGTTTTATTTTTTGAACAGTTAATCTGTCATTCTTGGTTAAGTGATCCTTCTCCATTGCC ATTGCATGTCTGCATGTAGAGTGCTATATGCTATTCTACTCATGACCTCACCTCATGGAAGGTAGAAGAT ACCTGGAGAATCTTTAATGAAGACAGAGGCAATAATTAGTAGACAGGAGAAGCTTTTGTATGAAGCAAGA TGAGAAAATATAAGGACACATAAGCGTAGAAAAAGGAAGCTAAGAGAAAATGTGATCAAAGTCCACAAAA GTCCTGCAAGATTAAAATAAAATGCTGAAAATGATAAATGAAATAATCAGTAACAATGTGCACCTGATTA TTAAGGCAAATGAGAGATTTATAATTGGCAGACAAGCTTGTCCACAAATATTGCATTGGTACCACAGTGT GTGAAATGAAATATGGCTGATGTGATGTGGTAGAATGGTAGGTTGATTCCTTCCGCCTCCCTTGATGCTG TTTTCTCTCCGATGCTGTGAACATAGAAGAGAGACTTTATCTGCATACCTTTCTGAAACCAATTTCATGG AACTAACTTACCATTGGAAGGTTAGTTTAACTTCTTCCTAGTGCAGAGATCCTGCTACAATATCCCTGTC AGACAGTCAACCACTTTCTGATCTTTGAAAGGTAATGACAGAGTACCTACTACCTCATAAGACAGTTCAT TCTACTCTTAGCTCTAATAATTAAATCGTTTCTCTTTTTAGTAAAATCAGTGATTGCCTTGCTATTTCAG TCCAGAATTGTTCAAATTCTATCAGAAATAACATCTAATAATTTCCCAGGCCCTCTTCTGCCTGAGAGTG CCTTAAGTCATCAAACATGGCCATCTTGTTACATGGTCTTTTTAAAAATCAGGAGTAGGAGTTGGCTTTT CACGATAACATATAACCTGACCATAGACGTGGAGGAGCCCAGCCAGAGTATACGACTGCATTTTGTAGGC ATTAGTGAGGAGCCAACATGCCACCCATCCATCCATTTCTTCATCCATTCAGTAAATATCCATTGAATTG CTAATAGGTACAAGGAAAGCTTTTAGGTTCTTATGATAAAACAAGGTTTTAAAAACAAATCCAAATTTTG TACAGTTTATACTCTAAAGGGAAAGTAGATATTTTTCTTACAGGCAAATTAACTGAGACAGGTAACTAAC TGAGACAAATGTTCTGATGGAAAGGAAGATGGTTCTTCAGCAGCATGTGTCAAAGGAGCATTAACATAAG CCAGGAGTTAGAGTTGGTGTTGGTCAAAGCGGGTTCCATGGGGAAGTGACTTGCACTAAGCTGTGAAAAA TGCATAGGAGTTAAAGGTACCTTCAGTCAGAGGGAACACTGTGTGAAAATCCCTCTGACAGCAGGTGTTG ACTTGCTTGAGGACTGAAAGAAGGCCAGTATGGCTGCAGTACAGAGAATCTTCAGAGGGCAGGATGGGGT CCCCTCGACAGAAGGAAAATGCAAGGCCTTGTAGAACATAATTAGAAATCTGTGGCCAGGCGCGGTGGCT CACGCCTGTAATCCCAACACTTTGGGAGGCTGAGGTGGGCGCATCACGAGGTGAGGAGCTCAAGACCAGC CTTAACAACATGGTGAAACCCCATCTTTACTAAAAAAATACAAAAATTAGTCAGGCGTGGTGGCATGAGC CTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGGCAGAGGTTGCAGTG AGCCAAGATTGCGCCACTGCACTCCAGCTTGGGTGACGGAGTGAGACTCCGTCTCAAAAAAAAAAAAAAG AAAGAAATCAGCCCTTGTTTCATAGCAGCAGTTTATTCATTTTCACTACTACATAAGATTCCATTTAATT GATAATTACATATACACATAAACTGATATACATATATATAGAGAGAGAGAATTGGTGTATTTTTATTGTT ATTTTAGTCATTGGAGGCCATTATGAATAATGCTGCTATGAATATTTATGTACATTATAAGCCTTATATA CTTATCTTTGTATGTTTGTATTTGTATGTGTGTTTCTCTTGACTGTACACCTGTGAATGGTATTACTGGA TGTTAAGGTAAGTAGATATTGAATTTTAATAAATAGCGTCCCAAACCATTTTCCAAAGTGTTATACCAAT TTAAGACGACTACTACTTCATAGTTTTTGTTTCTTGTCTTTTTTTTTTTTTTGAGACAGACAGGGTCTCA CTGTGTCATCCAAGCTGGAGTGCAGTGGTGCAATCATGACTCACTGCAGCTTTGAACTCCTGGGCTTAAG TTATCCTTGCCTCAGCCTCCCAAGTAGCTGGGACTAAAAACATGTGCCATTATACCTGGCTAATTTTGAA AATATTTTTTGTAAAGATAGGGTCTCCCTATGTTGACTAAGCTGGTCTCAAACCCCTGGCCTCAAGTGAT CCTCCAGCCTTGGCCTCCCAAAGTGCTGGGATTACTGGTGTCTGTGCCAGGTCCAGTTTCTTTCATTTTA AAATATGATTTTTTTTTAAGAAAAATTAGCTGTTCTTGAAGATATCTTAATATGGTTTTAGTATTTATTC CTGGTGACATTTGAAAATGTGCACTGCTCATATGTTTATATGCTTATTGGCCATGTCTTTCATTTTTTAA TCAGTTGATAAGCAATACAAATCGGTAACAAAACCAAAGCCACTAAGTCAAGCTGAAATGAGTCCTGCTG CATCTGCAGCCATCAGAAATGATGTCGCAAAGCAACGTGCTGCACCAAAAGTCTCTCCTCATGTTAAGGT AGGATAAGGAGAGTGGAGTGGTCTTTGTCCTTGTAAGAGCATCACTGTCACTGTCACTTCCCATATTGTT CTCTGTTCTTTATCTCACAGCATGCAAATAAGGGAAGCAAGGCCACAGCATGAAAAGCATTCTGAGTCAC AAAAACAGGAACTACCTTTGATTCATCAGATTAAACACCTGTTGAGCTTCTAATCTCTGCCAGGTTCTGG ACACATTAACACTTTGTTATGTTTTGGATTCTATAAGAAGAAAACTCTGAGATAGACCGTTGTTTACAGG AAGTCTATTTTAGAGCACTTTCAGAATTAATATCTGTGAGGAAGTGAAAGGAGAAGAAGAGGAAGAATGT CAAGTCCAATGTAGTTGCAATAGAGGCCTTGGCCTACCCTACAGGGAGCTCGGGAGCTGAGAATGTCTTT CAGGGCTCCCAAGATTTGTGAGGGAGTCTGTGGTTTGTACAGGCCCAGGCTCTGGGTCACATCAGAGATC CAATTCAGAGACTCTGACACTCGGTCTGGCATGCCTCTGTTTGTTTTCTGCTTGGTTCTTGACAGCAAAT TGCTTTTTTAAAAGTAATGTAAAAAAGCCCTTTATACACCTGCATGGACAAGGTGAGGTGGCCCCATTTA GCTGAGAGAGTAGTGGCTGGAGAGTGTCATTGGTGAGAATGATTACTTTAGTCCTGAGGGAGTGGCAGAC AACGTTAGAAAGGCCCAGCACAGAATCCACCACACATGCAGTTTCATTTCCTATGAAGCAGGTATTACAT TATTTTATACCTGTGTGAGCTCTAAAAACTGATGATATATACTTCATTCTCTTTGTCTAGAGGAACCATT TCCTCTGGGTTTGGCCCAGAAACTTCTGGATTTTTCAGGAAAACAAGGTTCAAGTATAAATGGTGTGATT CCCTCATCAGTAATGAAAATATGCATTTTTCAGTCTGGAAGACCCAAATAAAGATACATGGACCAAAGAG AAGGACTTCTGTAGTGGACCTCAGTGGAGCTGACCTTTCCCTGCATTGATCCAAATGCAGTCAGTTATGC TGCCCATCAGGGCCCCTTACTGGCCCAAGCTCCACTGCCCCAAGCTCCAGGTCACATCAGAGACACCCTT CAGAGACTCCTACGCTTGGCTTTTTATGCCTCTGTTTGTTTTGCCCTGTATTTCCCTTTGGTTCTAAATG GCAAGTGGCTTTTAAAAAGTAGTATTTTCTCCCAAAACAAACCAAAAAGAGGTGTCTTATCTCTGTTAAT TCAGAAAAATAAAAAACACAGAGAAGAGAATAAAATTATCTATAATTGTATCGTCTAGGAAAAAAATACA TTGATGTTGGTAAATATCTCTCTAGTGTGTTTGTGTGTGTGCTTTAACTGCTTATTTATCCAATAAGAAA CAGATTGTTTATCTGTTTAGGACCTTTCCCTTTATTGAATCAGTTATAACAGTTTATCATATTTCTCTAA AGCATTTTTAATATTTGCACAGTAATCTTTTTGTGACTATACCTATTTTATTTAACCAAATCTATTTTTT AGGTATTTAAATTATTTCTTTTTTTATAATTTCAAATAATAAGATGTACTTTTTAAATATAAACCTTAGT GCATAATTCATTATTTAAGGGTAAATCCATAAATGTAGTATTAATTCTCCTTTTAAATTTCTCCTTTAAC TCACTCATAAGATCTCTGAACTAGGTCTCCCCCTTAACTCACATTAAATGTAATCTGCATTTTGTTATGT ACAATGCTCCCTAGGAATTTGGGGAGCCCTGTGCTGGTCACTGAGCTCCCTCACTTTTATACCAGAGTAA AATGAACATTTAGGACAGTATTGGATAGAGAAACAAGGACACATGCCCGAATGGAATTGATAGAAGATGG AATCAGATTTGTCAGATTTACCCCGAGGCTTAGCAGTATTTCAGAAATCTGATGAAGTCTTTATATATAG TACATGGCAAAGCAAGGATTTGGTTTCAGGGATCCTACCTCCAAAACGTGTTACACCGTCTTATCTGAAT ACAGGAGTCGAAATCTTCCTTCTGCACTCTCTGTTCTATCTGGATCGTTCTAGGCCTCAACTCTCTTCGT ATCCCCTCTGTATCTCTTCCCTTGATTCCACCTATCTTCTGCTGGCTTTCTGAGGTTTAGCACTGTAGGT GAAGTAAGGTCCTTTCAATAGTACCTTTTTGACTCACAGCTGATATCTTTCTTCTCTTGTCTTCAGCCTG AACAGAAACAGATGGTGGCCCAGCAGGAATCTATCAGAGAAGGGTTTCAGAAGCGCTGTTTGCCAGTTAT GGTACTGAAAGCAAAGAAGCCCTTCACGTTTGAGACCCAAGAAGGCAAGCAGGAGATGTTTCATGCTACA GTGGCTACAGAAAAGGAATTCTTCTTTGTAAAAGTTTTTAATACACTGCTGAAAGATAAATTCATTCCAA AGAGAATAATTATAATAGCAAGATATTATCGGCACAGTGGTTTCTTAGAGGTAAATAGCGCCTCACGTGT GTTAGATGCTGAATCTGACCAAAAGGTTAATGTCCCGCTGAACATTATCAGAAAAGCTGGTGAAACCCCG AAGATCAACACGCTTCAAACTCAGCCCCTTGGAACAATTGTGAATGGTTTGTTTGTAGTCCAGAAGGTAA GTTTTCATATCTAATTTCATATTGATTAGTAAGAATAACGTATTTCCCATCTGATCTTAAAGAAACTTTG GAAATGGTTTTAATGTCTTTCTATATAGACAAAATAAAAAAATACAAAGTTCTAAAGAGCTGCAGAGTAA ACATGCCAAAATTCATACAAAAACTCAAAAATTGTTTTTATTGTCAAAAATGTCACGATCCTATTTCAAC TTACCCCAGTAGCCTCTGAAAAAGGAATTAGTTCATTCACATAATTTTTATTTCTGCATTATTTTTGTAC TTTGTACATATTATCTTTATTTTAAGTGACTATAGTTGTGATTATCTTTATTTTAAGTGACTATTGTTGT GAATGCAAAGTAAGTGTAGTTGAGTAATAAACCAGATTAATGACCTGAAAAACCAATACGCAAGGCAGGA TTAAAGAACTGTGATTAAATGAAGAAAACAGAAGAAAGAGTTAGCCTGAGGAGACTTTTTTTTTAATTAA AAAGTAAACTTTAATGTCAAAAATGCAAACTGGGGGAAGACAGAAAAGATCACACACAAGGCTGTCACTT CACACTTGGAAGGTTGCACGGCGGCCGGGCAGAGGCGCTCCTCACTTCCCAGACAGGGCCGCGGGGCAGA GGCGCTCCTCCAGGATACTTATTAGAAGTGAGAAATAATAAAGTATTTATTATGATTCTGAGCCTCAGGG AACTAGCCTTGTGGGATGACTTTTTCTGGTCTAGGGCAGGACCTAAAGAACCATAGAGAGAGAACCTGCT GCCCCTGCATTCAGAGCCTCAGAATAACCTCTGCTGCCCTGGGTTAGTTTCAGAAGGAATTGATAGGAAG ACTCTCCAGTCCTCCTGGAAAACTCAAGTGTAAAATGACCTTGGATAGGAAAGTCATGTTCTTTATCCCA GTTTTCAGCTTTCAATCTGGCCAGCTATCCACTCATATATACTGATTTAGTCCATAAAATTAAACCTAAA ATACGATCAATCTCCTAAATAACTGACCAACCTCCTGTTCCCTTTGGATCTAGACTTGATTGTGAATTGT TTCTTGTCTTTGATTACTTACTAGACTCTTGGCTGGGTCTTGCATCATTACCTCATGTCTCTCCTGGACT TGTTTTAAATAGCTCTCTTCAGGCTGGGCGCGGCAGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCCA AGGCGCATGGATCACCTGAGTTGAGGAGTTCCAGATCATCCTGGCCAACATGGCAAAACCTGTCTCTAGT AAAAATACAAAAATTAGCCGGGTGTATTGGCGGACACCTATAATCCCAGCTACTCGGGAGGCTGAGGCAA GAGAATCGCTTGAACCCAGGGCGTTGGAGGTTGCAGTGAGCCAAGATTGCGCCATCGCACTCCAGCCTGG GTGAAAGAGCGAAACTCCATTTCAAAAAATAAACAAATAGAATAAATAGCTCTCTTCCAACCCAGGGTCT TCTTTTTTCCCTTGACTAATCTGGCTGCTGGCCCTGGAGAAGCTCCATCTTCTCTATCCAGCAGTTGTTG CTTCTATGGGCCACCCTGGCCTCCTCCTAAAGGAAGGGAATTTAGGACTGGAAAGATAGGCATAGGAGAC AACATGTTCTAAGTAAGACACGTCTGCCTCCTCTGTGTGAACTTGCTAACATCTATTAGATATATACCTG CTAGTTTCAAAGCAGAAACATTTTTTCAAGTTGTCCCTTGAACAATGTAGGGATTAGGGCTTCTGACCCT GAGCAGTTGATAATCTGCATATAATTTTTGACTCCCCAAAAACTTAACTGCTTAATAGCCTACTCTTGAT CAGAAGACTTACGGACAACATAAGCAGTCACTTAACACATATTTTTGTGTTATACATATTATATACTATA TTCTTAAAAAGTAAGCTAGAGAAAAATGTTATTAATAAAATTATAAAAAAGAAAATATACTAACTATTCA TTAAGTGGAAGTAGATCATCATAAAGTTCTTCATCCTCATTGTCTTGATGTTAAGTAGACTGAGGAGGAA GAGGAGGGTTGGTCTTGCCATCTTGGGGTGGCAGAGACAGAGGAAAATTCCCATATAAATGGACCTGCAC AGGTAAAATCTGTGTTGTTCAAGAATCAACTGATTTCTTTTTAGAGCCTTCTTCTGGCATGTCTGATGTG TGACTGATGCGGCATTCATTAATCCGATTATCAGAGGCTGGGTGTTGATTTTCTTTTATAGGTAACAGAA AAGAAGAAAAACATATTATTTGACCTAAGTGACAACACTGGGAAAATGGAAGTACTGGGGGTTAGAAACG AGGACACAATGAAATGTAAGGAAGGAGATAAGGTTCGACTTACATTCTTCACACTGTCAAAAAATGGAGA AAAACTACAGCTGACATCTGGAGTTCATAGCACCATAAAGGTGGGAACTGCATGGAACAAAGTCAACTCT CCAAGGGGGTGATATTTTTTGTTTTCTATCAGAAAGCCGGACTGGAGCCATTGAACAGGATATAGAGTGG AAGACATTGATATTTAGTACACGTTCATCTCACAGAACTGAGGAACCTCCCTCTTAGGAAACATGTATTC TAGATACACAGTTAAGAGAACATGGGCTTTTCAAGGCAGAGGCGCATATTGTTGTGCCCACAGAGCCCAA AAAAGAGCTCCTTATTTATACTACAAGTCTAAAGCAGAAAGCTTGCCCAGAGTCGGAAAAGTCATTCTGA CTAATGTCTTTGAAAGTAGACAGACAATAAATACTTTGAGGACACATTTCCCTAGCCAGTCCCACCACGT CTGCACCTACCATAGTCCAGTGCAGTTAAGTCCATGTAAACCCCTACTCTTGACCTTCCACCACACCCTC CTACCCGTGTCCTGCCACTACTTGGTGCTCTTCCCCAGGTCTCAGTGTTGGTTGCACTGCCTGCTATCTC TGTAAGAGTGGAGGCCAAGATTTGAGAAATATGCGTATGTGACCTTGCTAAGTGGGAGTGTATTTCTCAG GTCAGATATTCACTTCAGGAGTATGATCCAAGGCAGACCAATGTATTAGAAGGGTGGGAACAAAATAATT TTATGAGAAGATGATACATACACTTCAGAAGGCCATAGTGACTGCAAACAGTGGAGGGGCCACTCATCGA CTGCATCTCAGACTGCATGTTTTTTTTCTCCATCCAGGTTATTAAGGCCAAAAAAAAAACATAGAGAAGT AAAAAGGACCAATTCAAGCCAACTGGTCTAAGCAGCATTTAATTGAAGAATATGTGATACAGCCTCTTCA ATCAGATTGTAAGTTACCTGAAAGCTGCAGTTCACAGGCTCCTCTCTCCACCAAATTAGGATAGAATAAT TGCTGGATAAACAAATTCAGAATATCAACAGATGATCACAATAAACATCTGTTTCTCATTCATTACA Download Select all
Length	14417
OMIM ID	604578
HGNC ID	HGNC:357
Unigene ID	Hs.733411
Ensembl ID	ENSG00000163568
PharmGKB ID	-

mRNA Information

mRNA ID	XM_005245617.3
Exon	join(1..263,10567..10986,13222..13410,14178..14417)
mRNA Sequence	>9447 TCAGCCAATTAGAGCTCCAGTTGTCACTCCTACCCACACTGGGCCTGGGGGTGAAGGGAAGTGT TTATTAGGGGTACATGTGAAGCCGTCCAGAAGTGTCAGAGTCTTTGTAGCTTTGAAAGTCACCT AGGTTATTTGGGCATGCTCTCCTGAGTCCTCTGCTAGTTAAGCTCTCTGAAAAGAAGGTGGCAG ACCCGGTTTGCTGATCGCCCCAGGGATCAGGAGGCTGATCCCAAAGTTGTCAGATGGAGAGTAA ATACAAGGAGATACTCTTGCTAACAGGCCTGGATAACATCACTGATGAGGAACTGGATAGGTTT AAGTTCTTTCTTTCAGACGAGTTTAATATTGCCACAGGCAAACTACATACTGCAAACAGAATAC AAGTAGCTACCTTGATGATTCAAAATGCTGGGGCGGTGTCTGCAGTGATGAAGACCATTCGTAT TTTTCAGAAGTTGAATTATATGCTTTTGGCAAAACGTCTTCAGGAGGAGAAGGAGAAAGTTGAT AAGCAATACAAATCGGTAACAAAACCAAAGCCACTAAGTCAAGCTGAAATGAGTCCTGCTGCAT CTGCAGCCATCAGAAATGATGTCGCAAAGCAACGTGCTGCACCAAAAGTCTCTCCTCATGTTAA GCCTGAACAGAAACAGATGGTGGCCCAGCAGGAATCTATCAGAGAAGGGTTTCAGAAGCGCTGT TTGCCAGTTATGGTACTGAAAGCAAAGAAGCCCTTCACGTTTGAGACCCAAGAAGGCAAGCAGG AGATGTTTCATGCTACAGTGGCTACAGAAAAGGAATTCTTCTTTGTAAAAGTTTTTAATACACT GCTGAAAGATAAATTCATTCCAAAGAGAATAATTATAATAGCAAGATATTATCGGCACAGTGGT TTCTTAGAGGTAAATAGCGCCTCACGTGTGTTAGATGCTGAATCTGACCAAAAGGTTAATGTCC CGCTGAACATTATCAGAAAAGCTGGTGAAACCCCGAAGATCAACACGCTTCAAACTCAGCCCCT TGGAACAATTGTGAATGGTTTGTTTGTAGTCCAGAAGGTAACAGAAAAGAAGAAAAACATATTA TTTGACCTAAGTGACAACACTGGGAAAATGGAAGTACTGGGGGTTAGAAACGAGGACACAATGA AATGTAAGGAAGGAGATAAGGTTCGACTTACATTCTTCACACTGTCAAAAAATGGAGAAAAACT ACAGCTGACATCTGGAGTTCATAGCACCATAAAGGTTATTAAGGCCAAAAAAAAAACATAGAGA AGTAAAAAGGACCAATTCAAGCCAACTGGTCTAAGCAGCATTTAATTGAAGAATATGTGATACA GCCTCTTCAATCAGATTGTAAGTTACCTGAAAGCTGCAGTTCACAGGCTCCTCTCTCCACCAAA TTAGGATAGAATAATTGCTGGATAAACAAATTCAGAATATCAACAGATGATCACAATAAACATC TGTTTCTCATTCC Download Select all
Length	1485

CDS Information

Location	join(3397..3658,8195..8328,10567..10986,13222..13410, 14178..14204)
CDS Sequence	>lcl\|NM_004833.1_cds_NP_004824.1_1 [gene=AIM2] [protein=interferon-inducible protein AIM2] [protein_id=NP_004824.1] [location=246..1277] ATGGAGAGTAAATACAAGGAGATACTCTTGCTAACAGGCCTGGATAACATCACTGATGAGGAACTGGATA GGTTTAAGTTCTTTCTTTCAGACGAGTTTAATATTGCCACAGGCAAACTACATACTGCAAACAGAATACA AGTAGCTACCTTGATGATTCAAAATGCTGGGGCGGTGTCTGCAGTGATGAAGACCATTCGTATTTTTCAG AAGTTGAATTATATGCTTTTGGCAAAACGTCTTCAGGAGGAGAAGGAGAAAGTTGATAAGCAATACAAAT CGGTAACAAAACCAAAGCCACTAAGTCAAGCTGAAATGAGTCCTGCTGCATCTGCAGCCATCAGAAATGA TGTCGCAAAGCAACGTGCTGCACCAAAAGTCTCTCCTCATGTTAAGCCTGAACAGAAACAGATGGTGGCC CAGCAGGAATCTATCAGAGAAGGGTTTCAGAAGCGCTGTTTGCCAGTTATGGTACTGAAAGCAAAGAAGC CCTTCACGTTTGAGACCCAAGAAGGCAAGCAGGAGATGTTTCATGCTACAGTGGCTACAGAAAAGGAATT CTTCTTTGTAAAAGTTTTTAATACACTGCTGAAAGATAAATTCATTCCAAAGAGAATAATTATAATAGCA AGATATTATCGGCACAGTGGTTTCTTAGAGGTAAATAGCGCCTCACGTGTGTTAGATGCTGAATCTGACC AAAAGGTTAATGTCCCGCTGAACATTATCAGAAAAGCTGGTGAAACCCCGAAGATCAACACGCTTCAAAC TCAGCCCCTTGGAACAATTGTGAATGGTTTGTTTGTAGTCCAGAAGGTAACAGAAAAGAAGAAAAACATA TTATTTGACCTAAGTGACAACACTGGGAAAATGGAAGTACTGGGGGTTAGAAACGAGGACACAATGAAAT GTAAGGAAGGAGATAAGGTTCGACTTACATTCTTCACACTGTCAAAAAATGGAGAAAAACTACAGCTGAC ATCTGGAGTTCATAGCACCATAAAGGTTATTAAGGCCAAAAAAAAAACATAG Download Select all
CCDS ID	CCDS1181.1

Protein Information

Protein ID	NP_004824.1
Protein Name	absent in melanoma 2
Molecular Wt. (Da)	38823
Protein Sequence	>9447 MESKYKEILLLTGLDNITDEELDRFKFFLSDEFNIATGKLHTANRIQVATLMIQNAGAVSAVMK TIRIFQKLNYMLLAKRLQEEKEKVDKQYKSVTKPKPLSQAEMSPAASAAIRNDVAKQRAAPKVS PHVKPEQKQMVAQQESIREGFQKRCLPVMVLKAKKPFTFETQEGKQEMFHATVATEKEFFFVKV FNTLLKDKFIPKRIIIIARYYRHSGFLEVNSASRVLDAESDQKVNVPLNIIRKAGETPKINTLQ TQPLGTIVNGLFVVQKVTEKKKNILFDLSDNTGKMEVLGVRNEDTMKCKEGDKVRLTFFTLSKN GEKLQLTSGVHSTIKVIKAKKKT Download Select all
Length	343
Uniprot ID	P02778
Ensembl Protein ID	ENSP00000305651

Post-translational Modification Information (Source : HPRD)

No matching records could be found.

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

No matching records from HPRD source could be found.

Pathway Information

Pathway Name	Pathway ID
Cytosolic DNA-sensing pathway	hsa04623

Structure Information

PDB ID	3RN2
Resolution	2.55
Method	X-RAY DIFFRACTION
Chains	A, B
Molecule	Interferon-inducible protein AIM2
Model	View

Domain Information

ID	Location	Description
cd08305	Oct-82	Pyrin
cl14633	Oct-82	DD superfamily
pfam02760	150-318	HIN
cl08357	150-318	HIN superfamily
pfam02758	Jun-83	PYRIN
cd08321	Sep-83	Pyrin_ASC-like
cd08320	Oct-84	Pyrin_NALPs

Ontology Information

HPRD ID	975
Molecular Class	Unclassified
Molecular Function	Transmembrane receptor protein tyrosine kinase activity (GO:0004714)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report

Drug Information

No matching records could be found.

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO