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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
IER2 9592 immediate early response 2  19ETR101 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
22120713   2012Cell line : 3T3, 1AS

Source : -

Sample Type : -

No. of Sample : -

Stage : -

Knockdown of Ier2 ,wounding assaysUp-regulation- Ier2 as a new player in the regulation of tumor progression and metastasis, and suggest that Ier2 may be useful prognostically and therapeutically in the management of cancer.


Gene Details



NC_000019.9 (13261282..13265722)

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Gene Type protein coding
Gene Family -
Description -  
Chromosome 19
Location 19p13.13
Start 13261282  
End 13265722  
Strand +  
Gene Sequence

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Length 4441  
OMIM ID -   
HGNC ID HGNC:28871   
Unigene ID Hs.501629   
Ensembl ID -   
PharmGKB ID PA134982230   

mRNA Information


mRNA ID ?NM_004907.2
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS12295.1



Protein Information


      
Protein IDNP_004898.2
Protein Nameimmediate early response 2
Molecular Wt. (Da)0
Protein Sequence

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Length 223  
Uniprot IDQ9UKU9
Ensembl Protein ID ENSP00000362516  



Post-translational Modification Information (Source : HPRD)


No matching records could be found.

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

No matching records from HPRD source could be found.

Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam057601-223  IER
cl156811-223  IER superfamily


Ontology Information


   
HPRD ID10574
Molecular ClassTranscription factor
Molecular FunctionChromatin binding (GO:0003682)
Biological ProcessCell communication (GO:0007154); Signal transduction (GO:0007165)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO