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General Information
- Evidence
- Gene
- mRNA
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- Protein
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- Enzyme
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- Domain
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 20039278 | 2010 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 54 Stage : - | - | Up-regulation | - | SCRN1 expression is a prognostic factor in CRC patients. Thirty of the 54 (55.5%) cases exhibited a higher expression of the SCRN1 gene in cancerous regions than marginal non-cancerous regions. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | |
| Description | This gene likely encodes a member of the secernin family of proteins. A similar protein in rat functions in regulation of exocytosis in mast cells. Alternatively spliced transcript variants have been described. |
| Chromosome | 7 |
| Location | 7p14.3-p14 |
| Start | 29920103 |
| End | 29990289 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 70187 |
| OMIM ID | 614965 |
| HGNC ID | HGNC:22192 |
| Unigene ID | Hs.520740 |
| Ensembl ID | ENSG00000136193 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_001145514.1 |
|---|---|
| Exon | join(1..108,21222..21381,34930..35111,46111..46313, 49414..49608,53569..53734,63658..63838,66175..70187) | mRNA Sequence | Download Select all |
| Length | 5286 |
CDS Information
| Location | join(50..108,21222..21381,34930..35111,46111..46313, 49414..49608,53569..53734,63658..63838,66175..66333) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS47567.1 |
Protein Information
| Protein ID | NP_001138985.1 |
|---|---|
| Protein Name | secernin 1 |
| Molecular Wt. (Da) | 46251 |
| Protein Sequence | Download Select all |
| Length | 414 |
| Uniprot ID | P52945 |
| Ensembl Protein ID | ENSP00000370421 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| COG4690 | 18-227 | PepD |
| cl17793 | 18-227 | Peptidase_C69 superfamily |
| pfam03577 | 76-231 | Peptidase_C69 |
Ontology Information
| HPRD ID | 4491 |
|---|---|
| Molecular Class | Protease |
| Molecular Function | Protein serine/threonine kinase activity (GO:0004674) |
| Biological Process | Cell communication (GO:0007154); Signal transduction (GO:0007165) |
Drug Information
No matching records could be found.