Search results:
General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 11876550 | 2001 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | - | Up-regulation | - | Cdk1/p34cdc2 was expressed in 11 out of 15 adenomas (73.3%) and in 18 out of 36 adenocarcinomas (50%). |
| 25511643 | 2014 | Cell line : - Source : Changhua Christian Hospital. Sample Type : CRC tumor No. of Sample : 164 Stage : TNM Stage I-IV. | Immunohistochemistry | Up-regulation | - | Cdk1 N/C expression ratio determined by IHC staining could be an independent prognostic marker for colorectal cancer. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Cyclin-dependent kinases |
| Description | The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009] |
| Chromosome | 10 |
| Location | 10q21.2 |
| Start | 62538089 |
| End | 62554610 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 16522 |
| OMIM ID | 116940 |
| HGNC ID | HGNC:1722 |
| Unigene ID | Hs.732435 |
| Ensembl ID | ENSG00000170312 |
| PharmGKB ID | PA99 |
mRNA Information
| mRNA ID | XM_006718082.1 |
|---|---|
| Exon | join(1..129,1811..1872,6375..6531,7334..7457,9730..9900, 13560..13723,13818..13959,15547..16522) | mRNA Sequence | Download Select all |
| Length | 1925 |
Protein Information
| Protein ID | XP_006718145.1 |
|---|---|
| Protein Name | cyclin-dependent kinase 1 |
| Molecular Wt. (Da) | 33964 |
| Protein Sequence | Download Select all |
| Length | 297 |
| Uniprot ID | P01138 |
| Ensembl Protein ID | ENSP00000358525 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 39 |
| S | Phosphorylation | 39 |
| T | Dephosphorylation | 14 |
| Y | Dephosphorylation | 15 |
| T | Dephosphorylation | 14 |
| Y | Dephosphorylation | 15 |
| Y | Phosphorylation | 15 |
| Y | Phosphorylation | 15 |
| Y | Phosphorylation | 15 |
| Y | Phosphorylation | 15 |
| T | Phosphorylation | 14 |
| T | Phosphorylation | 14 |
| T | Phosphorylation | 14 |
| T | Phosphorylation | 14 |
| T | Phosphorylation | 161 |
| Y | Phosphorylation | 15 |
| Y | Phosphorylation | 19;- |
| Y | Phosphorylation | 19;- |
| Y | Phosphorylation | 160;- |
| T | Phosphorylation | 161;- |
| Y | Phosphorylation | 19;- |
| Y | Phosphorylation | 19;- |
| Y | Phosphorylation | 19;- |
| Y | Phosphorylation | 19;- |
| Y | Phosphorylation | 19;- |
| Y | Phosphorylation | 19;- |
| Y | Phosphorylation | 19;- |
| Y | Phosphorylation | 19;- |
| T | Phosphorylation | 222 |
| T | Phosphorylation | 165 |
| S | Phosphorylation | 46 |
| S | Phosphorylation | 46 |
| Y | Phosphorylation | 77 |
| Y | Phosphorylation | 77 |
| Y | Phosphorylation | 4 |
| Y | Phosphorylation | 4 |
| T | Phosphorylation | 5 |
| T | Phosphorylation | 5 |
| S | Phosphorylation | 178 |
| S | Phosphorylation | 121 |
| K | Acetylation | 6 |
| K | Acetylation | 6 |
| K | Acetylation | 33 |
| K | Acetylation | 33 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 25 | ABL1 | 1809 | NP_009297.2 | in vitro;in vivo | 2183353 |
| 273 | AMPH | 2687 | NP_001626.1 | in vitro | 11113134 |
| 332 | BIRC5 | 4520 | NP_001012271.1 | in vitro;in vivo | 1 106 930 211 861 760 |
| 334 | APLP2 | 103 | NP_001633.1 | in vitro;in vivo | 9109675 |
| 367 | AR | 2437 | NP_000035.2 | in vitro;in vivo;yeast 2-hybrid | 125 693 659 725 910 |
| 672 | BRCA1 | 218 | NP_009231.2 | in vitro;in vivo | 9244350 |
| 699 | BUB1 | 3907 | NP_004327.1 | in vitro | 16760428 |
| 800 | CALD1 | 251 | NP_149129.2 | in vitro | 12613668 |
| 860 | RUNX2 | 2566 | NP_001019801.3 | in vitro | 16407259 |
| 993 | CDC25A | 305 | NP_001780.2 | in vitro;in vivo | 12411508 |
| 1026 | CDKN1A | 298 | NP_510867.1 | in vivo | 9467962 |
| 1104 | RCC1 | 1559 | NP_001041659.1 | in vitro | 15014043 |
| 1164 | CKS2 | 300 | NP_001818.1 | in vitro | 2227411 |
| 1390 | CREM | 444 | NP_853549.1 | in vitro;in vivo | 8404858 |
| 1457 | CSNK2A1 | 277 | NP_001886.1 | in vitro;in vivo | 75 927 731 400 350 |
| 1460 | CSNK2B | 278 | NP_001311.3 | in vitro;in vivo | 7578274 |
| 1523 | CUX1 | 295 | NP_853530.2 | in vitro | 11584018 |
| 1854 | DUT | 3165 | P33316 | in vitro;in vivo | 8631817 |
| 1869 | E2F1 | 1806 | NP_005216.1 | in vitro;in vivo | 8087847 |
| 1894 | ECT2 | 11860 | NP_060568.3 | in vitro | 16247472 |
| 1936 | EEF1D | 560 | NP_115754.2 | in vitro | 805 110 812 551 973 |
| 2189 | FANCG | 4262 | NP_004620.1 | in vitro | 15367677 |
| 2237 | FEN1 | 2670 | NP_004102.1 | in vitro | 12853968 |
| 2305 | FOXM1 | 3823 | NP_973731.1 | in vitro | 15024056 |
| 2670 | GFAP | 675 | NP_002046.1 | in vitro;in vivo | 782 226 412 177 195 |
| 2801 | GOLGA2 | 3989 | NP_004477.3 | in vitro;in vivo | 107 690 279 753 325 |
| 3159 | HMGA1 | 2829 | NP_665906.1 | in vitro;in vivo | 1939057 |
| 3603 | IL16 | 4329 | AAQ86961.1 | in vitro;in vivo | 12450396 |
| 3708 | ITPR1 | 925 | Q14643 | in vitro;in vivo | 1 463 519 216 237 110 |
| 3832 | KIF11 | 1023 | NP_004514.2 | in vitro;in vivo;yeast 2-hybrid | 92 359 428 548 803 |
| 3875 | KRT18 | 1020 | NP_000215.1 | in vivo | 952 411 315 368 451 |
| 3925 | STMN1 | 1047 | NP_001138926.1 | in vivo | 8 376 365 111 353 640 000 000 |
| 4000 | LMNA | 1035 | CAA27173.1 | in vitro;in vivo | 79 254 822 344 612 |
| 4001 | LMNB1 | 1036 | NP_005564.1 | in vitro;in vivo | 119 011 538 034 666 |
| 4134 | MAP4 | 1141 | NP_002366.2 | in vitro;in vivo | 939 832 011 683 421 |
| 4137 | MAPT | 1142 | NP_001116538.1 | in vitro | 9614189 |
| 4173 | MCM4 | 9094 | NP_005905.2 | in vivo | 16519687 |
| 4194 | MDM4 | 4082 | NP_002384.2 | in vitro | 15735705 |
| 4208 | MEF2C | 2809 | NP_002388.2 | in vitro | 16478538 |
| 4869 | NPM1 | 1246 | NP_002511.1 | in vitro;in vivo | 1 205 806 611 278 990 |
| 5339 | PLEC1 | 3180 | NP_958782.1 | in vitro;in vivo | 8626512 |
| 5727 | PTCH1 | 3200 | NP_000255.2 | in vitro;in vivo | 11331587 |
| 5770 | PTPN1 | 1477 | NP_002818.1 | in vitro | 84 911 879 600 099 |
| 5771 | PTPN2 | 6768 | NP_002819.1 | in vitro;in vivo | 15030318 |
| 5867 | RAB4A | 1541 | NP_004569.2 | in vitro | 1425574 |
| 5869 | RAB5B | 1544 | NP_002859.1 | in vitro | 10403367 |
| 5909 | RAP1GAP | 2609 | NP_001139130.1 | in vitro | 1406653 |
| 5925 | RB1 | 1574 | NP_000312.2 | in vivo | 1756735 |
| 6118 | RPA2 | 1566 | NP_002937.1 | in vitro;in vivo | 13 181 959 295 339 |
| 6198 | RPS6KB1 | 10202 | NP_003152.1 | in vitro;in vivo | 125 868 359 271 440 |
| 6241 | RRM2 | 1587 | NP_001025.1 | in vitro | 9990288 |
| 7048 | TGFBR2 | 1823 | NP_001020018.1 | in vitro;in vivo | 9926943 |
| 7083 | TK1 | 1771 | NP_003249.3 | in vitro | 957 515 314 697 231 |
| 7153 | TOP2A | 536 | NP_001058.2 | in vitro;in vivo | 763 516 012 569 090 |
| 7161 | TP73 | 3587 | NP_005418.1 | in vitro;in vivo | 12676926 |
| 7248 | TSC1 | 5594 | NP_000359.1 | in vitro;in vivo | 1 144 480 014 551 200 |
| 7317 | UBA1 | 2440 | NP_003325.2 | in vitro;in vivo | 77 245 837 673 335 |
| 7319 | UBE2A | 2422 | NP_003327.2 | in vivo | 11953320 |
| 7431 | VIM | 1899 | NP_003371.2 | in vitro | 798 305 015 345 747 |
| 8091 | HMGA2 | 2827 | NP_003474.1 | in vitro | 10636877 |
| 9113 | LATS1 | 9147 | NP_004681.1 | in vitro;in vivo;yeast 2-hybrid | 998 826 812 372 621 |
| 9232 | PTTG1 | 4998 | NP_004210.1 | in vitro;in vivo | 10656688 |
| 9585 | KIF20B | 9268 | BAB69456.1 | in vitro;in vivo | 11470801 |
| 9600 | PITPNM1 | 7497 | NP_004901.2 | in vitro;in vivo | 15125835 |
| 10657 | KHDRBS1 | 3926 | NP_006550.1 | in vitro;in vivo | 9315091 |
| 10763 | NES | 9020 | NP_006608.1 | in vitro;in vivo | 1 283 249 211 278 540 |
| 11075 | STMN2 | 9003 | NP_008960.2 | in vitro | 95 259 569 126 608 |
| 23225 | NUP210 | 6368 | NP_079199.2 | in vitro | 8672508 |
| 28984 | C13orf15 | 17970 | NP_054778.2 | in vitro;in vivo | 11687586 |
| 29924 | EPN1 | 6270 | NP_001123543.1 | in vitro | 10764745 |
| 54820 | NDE1 | 14815 | NP_060138.1 | in vitro | 12556484 |
| 55872 | PBK | 17822 | NP_060962.2 | in vitro | 15541388 |
| 55968 | NSFL1C | 9425 | NP_057227.2 | in vitro;in vivo | 12810701 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Cell cycle | hsa04110 |
| Epstein-Barr virus infection | hsa05169 |
| Gap junction | hsa04540 |
| Herpes simplex infection | hsa05168 |
| Oocyte meiosis | hsa04114 |
| p53 signaling pathway | hsa04115 |
| Progesterone-mediated oocyte maturation | hsa04914 |
| Viral carcinogenesis | hsa05203 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd07861 | 3-287 | STKc_CDK1_euk |
| cl21453 | 3-287 | PKc_like superfamily |
| cd07835 | 4-287 | STKc_CDK1_CdkB_like |
| cd07829 | 4-287 | STKc_CDK_like |
| cd07860 | 4-287 | STKc_CDK2_3 |
| cd07837 | 2-288 | STKc_CdkB_plant |
| cd07839 | 4-287 | STKc_CDK5 |
| cd07836 | 4-287 | STKc_Pho85 |
| cd07844 | 4-287 | STKc_PCTAIRE_like |
| cd07841 | 4-287 | STKc_CDK7 |
| cd07843 | 2-287 | STKc_CDC2L1 |
| cd07840 | 4-287 | STKc_CDK9_like |
| cd07871 | 1-287 | STKc_PCTAIRE3 |
| cd07873 | 1-297 | STKc_PCTAIRE1 |
| cd07838 | 4-287 | STKc_CDK4_6_like |
| cd07872 | 1-297 | STKc_PCTAIRE2 |
| cd07832 | 3-288 | STKc_CCRK |
| cd07845 | 3-289 | STKc_CDK10 |
| cd07866 | 1-287 | STKc_BUR1 |
| cd07833 | 2-287 | STKc_CDKL |
| cd07830 | 4-287 | STKc_MAK_like |
| cd07863 | 4-287 | STKc_CDK4 |
| cd07842 | 4-287 | STKc_CDK8_like |
| cd07870 | 4-287 | STKc_PFTAIRE2 |
| cd07834 | 4-290 | STKc_MAPK |
| cd07865 | 4-287 | STKc_CDK9 |
| cd05118 | 4-287 | STKc_CMGC |
| cd07869 | 2-290 | STKc_PFTAIRE1 |
| cd07862 | 2-287 | STKc_CDK6 |
| cd07864 | 4-286 | STKc_CDK12 |
| cd07847 | 2-287 | STKc_CDKL1_4 |
| cd07846 | 2-287 | STKc_CDKL2_3 |
| cd14137 | 4-290 | STKc_GSK3 |
| cd07852 | 4-292 | STKc_MAPK15-like |
| cd07831 | 4-287 | STKc_MOK |
| cd07849 | 2-286 | STKc_ERK1_2_like |
| cd07855 | 2-287 | STKc_ERK5 |
| cd07858 | 4-290 | STKc_TEY_MAPK |
| cd07857 | 4-288 | STKc_MPK1 |
| cd07851 | 4-287 | STKc_p38 |
| cd07848 | 10-287 | STKc_CDKL5 |
| cd07856 | 2-286 | STKc_Sty1_Hog1 |
| cd07880 | 2-290 | STKc_p38gamma |
| cd07859 | 4-290 | STKc_TDY_MAPK |
| cd14132 | 1-287 | STKc_CK2_alpha |
| cd07853 | 10-286 | STKc_NLK |
| cd00180 | 10-285 | PKc |
| cd07867 | 9-287 | STKc_CDC2L6 |
| cd05117 | 3-285 | STKc_CAMK |
| cd07879 | 2-290 | STKc_p38delta |
| cd07868 | 1-287 | STKc_CDK8 |
| cd06606 | 3-287 | STKc_MAPKKK |
| cd14003 | 3-286 | STKc_AMPK-like |
| cd07878 | 2-287 | STKc_p38beta |
| cd07877 | 2-293 | STKc_p38alpha |
| cd05122 | 3-287 | PKc_STE |
| cd07850 | 4-288 | STKc_JNK |
| cd14014 | 4-275 | STKc_PknB_like |
| cd14210 | 4-287 | PKc_DYRK |
| cd08215 | 3-287 | STKc_Nek |
| cd14007 | 3-285 | STKc_Aurora |
| cd14002 | 2-286 | STKc_STK36 |
| cd13999 | 10-206 | STKc_MAP3K-like |
| cd14133 | 4-287 | PKc_DYRK_like |
| cd07854 | 4-289 | STKc_MAPK4_6 |
| cd08217 | 3-206 | STKc_Nek2 |
| cd06627 | 4-287 | STKc_Cdc7_like |
| cd07874 | 1-288 | STKc_JNK3 |
| cd14009 | 10-286 | STKc_ATG1_ULK_like |
| cd07876 | 1-286 | STKc_JNK2 |
| cd14008 | 10-287 | STKc_LKB1_CaMKK |
| cd05123 | 10-287 | STKc_AGC |
| cd06614 | 4-288 | STKc_PAK |
| cd06632 | 4-286 | STKc_MEKK1_plant |
| cd14069 | 2-287 | STKc_Chk1 |
| cd14081 | 6-287 | STKc_BRSK1_2 |
| cd07875 | 1-288 | STKc_JNK1 |
| cd06612 | 2-287 | STKc_MST1_2 |
| cd14006 | 10-286 | STKc_MLCK-like |
| cd05579 | 10-291 | STKc_MAST_like |
| cd06623 | 2-285 | PKc_MAPKK_plant_like |
| cd14225 | 4-287 | PKc_DYRK4 |
| cd14212 | 4-287 | PKc_YAK1 |
| cd14074 | 8-286 | STKc_SNRK |
| cd14663 | 10-286 | STKc_SnRK3 |
| cd06609 | 2-286 | STKc_MST3_like |
| cd14098 | 3-286 | STKc_Rad53_Cds1 |
| cd14099 | 2-287 | STKc_PLK |
| cd06626 | 9-286 | STKc_MEKK4 |
| cd14131 | 3-286 | PKc_Mps1 |
| cd14086 | 2-292 | STKc_CaMKII |
| cd08224 | 3-207 | STKc_Nek6_7 |
| cd14226 | 1-288 | PKc_DYRK1 |
| cd06611 | 7-292 | STKc_SLK_like |
| cd14019 | 2-287 | STKc_Cdc7 |
| cd13996 | 2-275 | STKc_EIF2AK |
| cd14079 | 4-287 | STKc_AMPK_alpha |
| cd14185 | 10-286 | STKc_DCKL3 |
| cd05581 | 2-287 | STKc_PDK1 |
| cd13994 | 10-287 | STKc_HAL4_like |
| cd14095 | 4-286 | STKc_DCKL |
| cd06629 | 4-286 | STKc_Bck1_like |
| cd06610 | 2-287 | STKc_OSR1_SPAK |
| cd14121 | 8-286 | STKc_ULK3 |
| cd14094 | 2-296 | STKc_CASK |
| cd08529 | 3-218 | STKc_FA2-like |
| cd06613 | 3-287 | STKc_MAP4K3_like |
| cd14119 | 10-287 | STKc_LKB1 |
| cd14084 | 4-286 | STKc_Chk2 |
| cd00192 | 8-191 | PTKc |
| cd14093 | 2-287 | STKc_PhKG |
| cd06605 | 2-292 | PKc_MAPKK |
| cd06917 | 4-202 | STKc_NAK1_like |
| cd13993 | 4-277 | STKc_Pat1_like |
| cd14134 | 4-287 | PKc_CLK |
| cd14073 | 4-208 | STKc_NUAK |
| cd08530 | 3-223 | STKc_CNK2-like |
| cd14116 | 1-286 | STKc_Aurora-A |
| cd13997 | 3-285 | PKc_Wee1_like |
| cd14077 | 3-286 | STKc_Kin1_2 |
| cd06647 | 4-287 | STKc_PAK_I |
| cd06628 | 10-286 | STKc_Byr2_like |
| cd05572 | 10-291 | STKc_cGK |
| cd14181 | 2-287 | STKc_PhKG2 |
| cd14194 | 1-286 | STKc_DAPK1 |
| cd06625 | 10-287 | STKc_MEKK3_like |
| cd14224 | 4-286 | PKc_DYRK2_3 |
| cd14135 | 4-287 | STKc_PRP4 |
| cd14085 | 1-297 | STKc_CaMKIV |
| cd14080 | 4-287 | STKc_TSSK-like |
| cd14167 | 2-286 | STKc_CaMKI_alpha |
| cd14071 | 4-287 | STKc_SIK |
| cd06630 | 4-223 | STKc_MEKK1 |
| cd14120 | 10-286 | STKc_ULK1_2-like |
| cd08220 | 3-230 | STKc_Nek8 |
| cd05580 | 2-291 | STKc_PKA_like |
| cd14105 | 1-286 | STKc_DAPK |
| cd14092 | 5-289 | STKc_MSK_C |
| cd14117 | 1-286 | STKc_Aurora-B_like |
| cd14096 | 2-286 | STKc_RCK1-like |
| cd05578 | 10-287 | STKc_Yank1 |
| cd14118 | 10-277 | STKc_CAMKK |
| cd06655 | 2-287 | STKc_PAK2 |
| cd14166 | 2-288 | STKc_CaMKI_gamma |
| cd08219 | 3-208 | STKc_Nek3 |
| cd14004 | 3-287 | STKc_PASK |
| cd08218 | 4-218 | STKc_Nek1 |
| cd08225 | 4-223 | STKc_Nek5 |
| cd05570 | 10-291 | STKc_PKC |
| cd06608 | 2-286 | STKc_myosinIII_N_like |
| cd06648 | 2-287 | STKc_PAK_II |
| cd06631 | 4-286 | STKc_YSK4 |
| cd14202 | 3-217 | STKc_ULK1 |
| cd14083 | 8-286 | STKc_CaMKI |
| cd14072 | 4-218 | STKc_MARK |
| cd08228 | 1-207 | STKc_Nek6 |
| cd14161 | 4-194 | STKc_NUAK2 |
| cd08223 | 3-286 | STKc_Nek4 |
| cd14046 | 3-284 | STKc_EIF2AK4_GCN2_rpt2 |
| cd06656 | 2-287 | STKc_PAK3 |
| cd14078 | 8-286 | STKc_MELK |
| cd06644 | 7-286 | STKc_STK10 |
| cd06641 | 2-202 | STKc_MST3 |
| cd14097 | 4-286 | STKc_STK33 |
| cd14201 | 3-217 | STKc_ULK2 |
| cd14103 | 10-286 | STKc_MLCK |
| cd14109 | 2-287 | PK_Unc-89_rpt1 |
| cd08528 | 3-226 | STKc_Nek10 |
| cd06654 | 2-287 | STKc_PAK1 |
| cd06642 | 4-202 | STKc_STK25 |
| cd14175 | 4-291 | STKc_RSK1_C |
| cd05611 | 7-291 | STKc_Rim15_like |
| cd05612 | 2-291 | STKc_PRKX_like |
| cd06633 | 2-216 | STKc_TAO3 |
| cd05573 | 2-291 | STKc_ROCK_NDR_like |
| cd14182 | 2-287 | STKc_PhKG1 |
| cd14047 | 2-197 | STKc_EIF2AK2_PKR |
| cd14196 | 1-286 | STKc_DAPK2 |
| cd14162 | 4-193 | STKc_TSSK4-like |
| cd06643 | 2-259 | STKc_SLK |
| cd06607 | 4-204 | STKc_TAO |
| cd14195 | 1-286 | STKc_DAPK3 |
| cd14169 | 4-286 | STKc_CaMKI_beta |
| cd14091 | 3-292 | STKc_RSK_C |
| cd08222 | 4-286 | STKc_Nek11 |
| cd14070 | 9-202 | STKc_HUNK |
| cd14111 | 2-207 | STKc_SPEG_rpt2 |
| cd14136 | 4-287 | STKc_SRPK |
| cd14106 | 8-287 | STKc_DRAK |
| cd06659 | 1-287 | STKc_PAK6 |
| cd06640 | 2-286 | STKc_MST4 |
| cd14010 | 8-286 | STKc_ULK4 |
| cd06624 | 10-286 | STKc_ASK |
| cd14114 | 4-287 | STKc_Twitchin_like |
| cd14065 | 10-202 | PKc_LIMK_like |
| cd05609 | 3-291 | STKc_MAST |
| cd14005 | 9-287 | STKc_PIM |
| cd14082 | 8-286 | STKc_PKD |
| cd06645 | 2-286 | STKc_MAP4K3 |
| cd14180 | 10-277 | STKc_MSK2_C |
| cd14186 | 2-286 | STKc_PLK4 |
| cd05038 | 5-199 | PTKc_Jak_rpt2 |
| cd14049 | 3-197 | STKc_EIF2AK1_HRI |
| cd05584 | 10-291 | STKc_p70S6K |
| cd05601 | 10-291 | STKc_CRIK |
| cd06650 | 2-291 | PKc_MEK1 |
| cd13985 | 10-210 | STKc_GAK_like |
| cd14058 | 10-228 | STKc_TAK1 |
| cd13983 | 8-287 | STKc_WNK |
| cd14076 | 4-286 | STKc_Kin4 |
| cd05148 | 2-199 | PTKc_Srm_Brk |
| cd06620 | 2-287 | PKc_Byr1_like |
| cd06646 | 2-202 | STKc_MAP4K5 |
| cd06621 | 2-297 | PKc_Pek1_like |
| cd14176 | 4-291 | STKc_RSK2_C |
| cd14168 | 8-286 | STKc_CaMKI_delta |
| cd14198 | 8-287 | STKc_DRAK2 |
| cd05048 | 8-197 | PTKc_Ror |
| cd06652 | 10-243 | STKc_MEKK2 |
| cd06653 | 10-230 | STKc_MEKK3_like_u1 |
| cd08229 | 8-207 | STKc_Nek7 |
| cd13990 | 4-286 | STKc_TLK |
| cd05599 | 2-211 | STKc_NDR_like |
| cd14665 | 4-286 | STKc_SnRK2-3 |
| cd13987 | 10-279 | STKc_SBK1 |
| cd14087 | 10-286 | STKc_PSKH1 |
| cd14050 | 4-199 | PKc_Myt1 |
| cd06635 | 4-216 | STKc_TAO1 |
| cd14090 | 3-286 | STKc_Mnk |
| cd14066 | 10-216 | STKc_IRAK |
| cd06622 | 6-297 | PKc_PBS2_like |
| cd05619 | 1-291 | STKc_nPKC_theta |
| cd14061 | 10-213 | STKc_MLK |
| cd13979 | 8-209 | STKc_Mos |
| cd14178 | 4-286 | STKc_RSK3_C |
| cd14088 | 18-286 | STKc_CaMK_like |
| cd05039 | 1-197 | PTKc_Csk_like |
| cd06634 | 4-216 | STKc_TAO2 |
| cd05079 | 6-277 | PTKc_Jak1_rpt2 |
| cd13989 | 10-199 | STKc_IKK |
| cd14113 | 4-287 | STKc_Trio_C |
| cd06636 | 7-218 | STKc_MAP4K4_6_N |
| cd13982 | 8-287 | STKc_IRE1 |
| cd05041 | 8-200 | PTKc_Fes_like |
| cd14205 | 7-199 | PTKc_Jak2_rpt2 |
| cd14177 | 4-286 | STKc_RSK4_C |
| cd06637 | 7-293 | STKc_TNIK |
| cd14107 | 4-287 | STKc_obscurin_rpt1 |
| cd05577 | 10-291 | STKc_GRK |
| cd05600 | 1-291 | STKc_Sid2p_like |
| cd06651 | 10-286 | STKc_MEKK3 |
| cd14183 | 2-289 | STKc_DCKL1 |
| cd06639 | 7-286 | STKc_myosinIIIB_N |
| cd14165 | 10-287 | STKc_TSSK1_2-like |
| cd06615 | 2-287 | PKc_MEK |
| cd05585 | 10-291 | STKc_YPK1_like |
| cd14211 | 4-286 | STKc_HIPK |
| cd14155 | 10-197 | PKc_TESK |
| cd14209 | 2-291 | STKc_PKA |
| cd14164 | 4-207 | STKc_TSSK6-like |
| cd14146 | 10-213 | STKc_MLK4 |
| cd14179 | 10-281 | STKc_MSK1_C |
| cd14016 | 4-192 | STKc_CK1 |
| cd14110 | 4-207 | STKc_obscurin_rpt2 |
| cd05620 | 10-291 | STKc_nPKC_delta |
| cd14222 | 10-197 | STKc_LIMK2 |
| cd14052 | 3-199 | PTKc_Wee1_fungi |
| cd05592 | 10-291 | STKc_nPKC_theta_like |
| cd06658 | 9-287 | STKc_PAK5 |
| cd14039 | 10-278 | STKc_IKK_alpha |
| cd14216 | 4-287 | STKc_SRPK1 |
| cd06649 | 2-286 | PKc_MEK2 |
| cd05598 | 3-291 | STKc_LATS |
| cd05571 | 10-291 | STKc_PKB |
| cd13977 | 4-275 | STKc_PDIK1L |
| cd06657 | 9-287 | STKc_PAK4 |
| cd14154 | 10-197 | STKc_LIMK |
| cd14048 | 3-197 | STKc_EIF2AK3_PERK |
| cd14193 | 6-286 | STKc_MLCK4 |
| cd05595 | 10-293 | STKc_PKB_beta |
| cd05112 | 2-197 | PTKc_Itk |
| cd14192 | 8-287 | STKc_MLCK3 |
| cd14214 | 2-287 | PKc_CLK3 |
| cd14229 | 4-286 | STKc_HIPK3 |
| cd14059 | 10-199 | STKc_MAP3K12_13 |
| cd14191 | 4-287 | STKc_MLCK1 |
| cd14184 | 2-286 | STKc_DCKL2 |
| cd05068 | 7-199 | PTKc_Frk_like |
| cd05034 | 8-218 | PTKc_Src_like |
| cd14190 | 8-287 | STKc_MLCK2 |
| cd14038 | 9-199 | STKc_IKK_beta |
| cd06617 | 2-201 | PKc_MKK3_6 |
| cd05590 | 10-291 | STKc_nPKC_eta |
| cd05610 | 1-291 | STKc_MASTL |
| cd05582 | 10-234 | STKc_RSK_N |
| cd05593 | 1-293 | STKc_PKB_gamma |
| cd05607 | 4-203 | STKc_GRK7 |
| cd14199 | 1-191 | STKc_CaMKK2 |
| cd14221 | 10-197 | STKc_LIMK1 |
| cd05059 | 3-199 | PTKc_Tec_like |
| cd08221 | 4-287 | STKc_Nek9 |
| cd06616 | 2-293 | PKc_MKK4 |
| cd05583 | 10-290 | STKc_MSK_N |
| cd05080 | 6-200 | PTKc_Tyk2_rpt2 |
| cd14173 | 8-286 | STKc_Mnk2 |
| cd14213 | 4-287 | PKc_CLK1_4 |
| cd13978 | 10-216 | STKc_RIP |
| cd14163 | 10-214 | STKc_TSSK3-like |
| cd05084 | 8-196 | PTKc_Fes |
| cd14147 | 8-206 | STKc_MLK3 |
| cd06618 | 2-291 | PKc_MKK7 |
| cd14174 | 8-286 | STKc_Mnk1 |
| cd06638 | 7-286 | STKc_myosinIIIA_N |
| cd05056 | 2-294 | PTKc_FAK |
| cd05053 | 2-199 | PTKc_FGFR |
| cd14197 | 9-287 | STKc_DRAK1 |
| cd05083 | 8-197 | PTKc_Chk |
| cd05091 | 7-246 | PTKc_Ror2 |
| cd14101 | 4-210 | STKc_PIM2 |
| cd14108 | 3-216 | STKc_SPEG_rpt1 |
| cd14000 | 10-234 | STKc_LRRK |
| cd14012 | 10-286 | PK_eIF2AK_GCN2_rpt1 |
| cd05049 | 2-223 | PTKc_Trk |
| cd14227 | 4-286 | STKc_HIPK2 |
| cd05597 | 2-291 | STKc_DMPK_like |
| cd05614 | 3-291 | STKc_MSK2_N |
| cd05032 | 1-199 | PTKc_InsR_like |
| cd14104 | 8-286 | STKc_Titin |
| cd05596 | 2-208 | STKc_ROCK |
| cd05040 | 8-199 | PTKc_Ack_like |
| cd14156 | 10-202 | PKc_LIMK_like_unk |
| cd14662 | 4-286 | STKc_SnRK2 |
| cd05052 | 9-199 | PTKc_Abl |
| cd14089 | 3-286 | STKc_MAPKAPK |
| cd14200 | 4-286 | STKc_CaMKK1 |
| cd14148 | 10-213 | STKc_MLK2 |
| cd06619 | 2-198 | PKc_MKK5 |
| cd14145 | 8-246 | STKc_MLK1 |
| cd14036 | 10-204 | STKc_GAK |
| cd05586 | 10-274 | STKc_Sck1_like |
| cd05081 | 7-199 | PTKc_Jak3_rpt2 |
| cd05113 | 2-199 | PTKc_Btk_Bmx |
| cd05095 | 8-199 | PTKc_DDR2 |
| cd13986 | 4-296 | STKc_16 |
| cd13968 | 10-148 | PKc_like |
| cd14187 | 1-287 | STKc_PLK1 |
| cd05575 | 10-291 | STKc_SGK |
| cd05616 | 3-215 | STKc_cPKC_beta |
| cd14215 | 2-287 | PKc_CLK2 |
| cd05624 | 2-291 | STKc_MRCK_beta |
| cd05067 | 7-199 | PTKc_Lck_Blk |
| cd05099 | 10-218 | PTKc_FGFR4 |
| cd05605 | 10-291 | STKc_GRK4_like |
| cd05085 | 8-196 | PTKc_Fer |
| cd05591 | 10-291 | STKc_nPKC_epsilon |
| cd14075 | 9-193 | STKc_NIM1 |
| cd14228 | 4-286 | STKc_HIPK1 |
| cd05615 | 1-215 | STKc_cPKC_alpha |
| cd14115 | 10-286 | STKc_Kalirin_C |
| cd05098 | 10-257 | PTKc_FGFR1 |
| cd05621 | 2-256 | STKc_ROCK2 |
| cd14011 | 18-289 | PK_SCY1_like |
| cd14158 | 9-237 | STKc_IRAK4 |
| cd05072 | 7-246 | PTKc_Lyn |
| cd05097 | 8-221 | PTKc_DDR_like |
| cd05604 | 10-205 | STKc_SGK3 |
| cd14171 | 8-286 | STKc_MAPKAPK5 |
| cd14013 | 8-287 | STKc_SNT7_plant |
| cd05603 | 10-214 | STKc_SGK2 |
| cd14203 | 9-249 | PTKc_Src_Fyn_like |
| cd05071 | 9-247 | PTKc_Src |
| cd14112 | 2-193 | STKc_Unc-89_rpt2 |
| cd14218 | 4-287 | STKc_SRPK3 |
| cd05100 | 10-218 | PTKc_FGFR3 |
| cd05602 | 3-205 | STKc_SGK1 |
| cd05090 | 7-197 | PTKc_Ror1 |
| cd05050 | 10-197 | PTKc_Musk |
| cd14033 | 9-218 | STKc_WNK4 |
| cd14060 | 11-206 | STKc_MLTK |
| cd05082 | 1-197 | PTKc_Csk |
| cd05069 | 9-247 | PTKc_Yes |
| cd14189 | 4-287 | STKc_PLK3 |
| cd05114 | 5-218 | PTKc_Tec_Rlk |
| cd05101 | 10-218 | PTKc_FGFR2 |
| cd14027 | 13-230 | STKc_RIP1 |
| cd05622 | 2-234 | STKc_ROCK1 |
| cd13991 | 2-189 | STKc_NIK |
| cd05608 | 10-291 | STKc_GRK1 |
| cd05574 | 3-291 | STKc_phototropin_like |
| cd08226 | 18-297 | PK_STRAD_beta |
| cd14159 | 10-208 | STKc_IRAK1 |
| cd14040 | 2-213 | STKc_TLK1 |
| cd14037 | 5-191 | STKc_NAK_like |
| cd05060 | 8-191 | PTKc_Syk_like |
| cd05623 | 2-291 | STKc_MRCK_alpha |
| cd08216 | 16-198 | PK_STRAD |
| cd14041 | 4-213 | STKc_TLK2 |
| cd14062 | 10-224 | STKc_Raf |
| cd05618 | 1-284 | STKc_aPKC_iota |
| cd05051 | 7-223 | PTKc_DDR |
| cd05630 | 10-291 | STKc_GRK6 |
| cd13988 | 10-199 | STKc_TBK1 |
| cd05629 | 2-204 | STKc_NDR_like_fungal |
| cd13998 | 8-200 | STKc_TGFbR-like |
| cd14100 | 10-218 | STKc_PIM1 |
| cd05594 | 1-287 | STKc_PKB_alpha |
| cd14031 | 9-215 | STKc_WNK3 |
| cd05033 | 3-199 | PTKc_EphR |
| cd05587 | 10-214 | STKc_cPKC |
| cd05631 | 10-291 | STKc_GRK4 |
| cd05045 | 10-199 | PTKc_RET |
| cd14102 | 10-218 | STKc_PIM3 |
| cd14172 | 2-286 | STKc_MAPKAPK3 |
| cd05617 | 1-204 | STKc_aPKC_zeta |
| cd05632 | 10-209 | STKc_GRK5 |
| cd14054 | 8-250 | STKc_BMPR2_AMHR2 |
| cd05057 | 6-202 | PTKc_EGFR_like |
| cd14064 | 10-205 | PKc_TNNI3K |
| cd14032 | 9-215 | STKc_WNK2_like |
| cd05092 | 9-205 | PTKc_TrkA |
| cd05588 | 10-202 | STKc_aPKC |
| cd05096 | 8-197 | PTKc_DDR1 |
| cd13992 | 12-223 | PK_GC |
| cd05613 | 10-291 | STKc_MSK1_N |
| cd05075 | 10-200 | PTKc_Axl |
| cd14217 | 4-287 | STKc_SRPK2 |
| cd14223 | 3-197 | STKc_GRK2 |
| cd05116 | 9-196 | PTKc_Syk |
| cd14068 | 10-248 | STKc_LRRK2 |
| cd14188 | 4-287 | STKc_PLK2 |
| cd05062 | 2-199 | PTKc_IGF-1R |
| cd05093 | 9-223 | PTKc_TrkB |
| cd05606 | 10-291 | STKc_beta_ARK |
| cd14204 | 10-200 | PTKc_Mer |
| cd05633 | 1-234 | STKc_GRK3 |
| cd14063 | 8-197 | PK_KSR |
| cd05063 | 5-244 | PTKc_EphR_A2 |
| cd05065 | 4-197 | PTKc_EphR_B |
| cd05044 | 10-199 | PTKc_c-ros |
| cd05058 | 8-200 | PTKc_Met_Ron |
| cd05108 | 3-199 | PTKc_EGFR |
| cd05036 | 2-197 | PTKc_ALK_LTK |
| cd14030 | 9-215 | STKc_WNK1 |
| cd05066 | 6-197 | PTKc_EphR_A |
| cd05115 | 9-196 | PTKc_Zap-70 |
| cd05094 | 9-223 | PTKc_TrkC |
| cd14664 | 10-211 | STK_BAK1_like |
| cd05626 | 4-204 | STKc_LATS2 |
| cd05046 | 7-207 | PTK_CCK4 |
| cd05627 | 1-204 | STKc_NDR2 |
| cd13995 | 10-202 | STKc_MAP3K8 |
| cd05628 | 2-204 | STKc_NDR1 |
| cd05070 | 7-218 | PTKc_Fyn |
| cd14053 | 8-246 | STKc_ACVR2 |
| cd14025 | 8-210 | STKc_RIP4_like |
| cd14017 | 4-153 | STKc_TTBK |
| cd14170 | 2-288 | STKc_MAPKAPK2 |
| cd14056 | 8-237 | STKc_TGFbR_I |
| cd05589 | 10-209 | STKc_PKN |
| cd05035 | 10-200 | PTKc_TAM |
| cd05073 | 8-199 | PTKc_Hck |
| cd05103 | 83-256 | PTKc_VEGFR2 |
| cd05043 | 12-199 | PTK_Ryk |
| cd14020 | 50-288 | STKc_KIS |
| cd14153 | 8-201 | PK_KSR2 |
| cd05061 | 2-199 | PTKc_InsR |
| cd05047 | 10-199 | PTKc_Tie |
| cd05625 | 4-234 | STKc_LATS1 |
| cd05110 | 6-199 | PTKc_HER4 |
| cd14142 | 5-198 | STKc_ACVR1_ALK1 |
| cd14207 | 107-197 | PTKc_VEGFR1 |
| cd05054 | 3-223 | PTKc_VEGFR |
| cd14152 | 8-200 | STKc_KSR1 |
| cd14143 | 8-198 | STKc_TGFbR1_ACVR1b_ACVR1c |
| cd14150 | 7-224 | STKc_A-Raf |
| cd05089 | 2-199 | PTKc_Tie1 |
| cd14042 | 27-205 | PK_GC-A_B |
| COG0510 | 42-147 | CotS |
| PLN00009 | 1-293 | PLN00009 |
| pfam00069 | 4-287 | Pkinase |
| smart00220 | 4-287 | S_TKc |
| PTZ00024 | 2-288 | PTZ00024 |
| PTZ00036 | 10-297 | PTZ00036 |
| COG0515 | 3-291 | SPS1 |
| smart00219 | 5-191 | TyrKc |
| smart00221 | 5-191 | STYKc |
| pfam07714 | 5-199 | Pkinase_Tyr |
| PTZ00263 | 1-291 | PTZ00263 |
| PLN00034 | 1-191 | PLN00034 |
| PTZ00266 | 1-213 | PTZ00266 |
| PHA03209 | 4-290 | PHA03209 |
| PHA03212 | 51-290 | PHA03212 |
| PTZ00267 | 21-209 | PTZ00267 |
| PHA03210 | 51-288 | PHA03210 |
| TIGR03903 | 26-215 | TOMM_kin_cyc |
| PHA03211 | 13-287 | PHA03211 |
| PHA03207 | 50-287 | PHA03207 |
| PRK13184 | 1-199 | pknD |
| PTZ00426 | 2-291 | PTZ00426 |
| PLN03225 | 2-288 | PLN03225 |
| PTZ00284 | 10-286 | PTZ00284 |
| PTZ00283 | 10-208 | PTZ00283 |
Ontology Information
| HPRD ID | 574 |
|---|---|
| Molecular Class | Serine/threonine kinase |
| Molecular Function | Extracellular matrix structural constituent (GO:0005201) |
| Biological Process | Cell growth and/or maintenance (GO:0008151) |
Drug Information
No matching records could be found.