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General Information
- Evidence
- Gene
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- Enzyme
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Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25516230 | 2014 | Cell line : - Source : - Sample Type : Hospital-based case-control study No. of Sample : 341 cases and 727 controls Stage : - | Meta analysis | Polymorhpism | - | Variant rs1342387 on ADIPOR1 may be a novel CRC susceptibility factor. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | GPCR / Unclassified : Adiponectin receptors |
| Description | This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2014] | Chromosome | 1 |
| Location | 1q32.1 |
| Start | 202909960 |
| End | 202927700 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 17741 |
| OMIM ID | 607945 |
| HGNC ID | HGNC:24040 |
| Unigene ID | Hs.5298 |
| Ensembl ID | ENSG00000159346 |
| PharmGKB ID | PA134861801 |
Protein Information
| Protein ID | NP_001277482.1 |
|---|---|
| Protein Name | adiponectin receptor 1 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 375 |
| Uniprot ID | Q9HDC5 |
| Ensembl Protein ID | ENSP00000344488 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Adipocytokine signaling pathway | hsa04920 |
| AMPK signaling pathway | hsa04152 |
| Longevity regulating pathway - mammal | hsa04211 |
| Non-alcoholic fatty liver disease (NAFLD) | hsa04932 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam03006 | 129-352 | HlyIII |
| cl03831 | 129-352 | HlyIII superfamily |
| COG1272 | 105-355 | YqfA |
| TIGR01065 | 134-355 | hlyIII |
Ontology Information
| HPRD ID | 6157 |
|---|---|
| Molecular Class | Integral membrane protein |
| Molecular Function | Catalytic activity (GO:0003824) |
| Biological Process | Metabolism (GO:0008152); Energy pathways (GO:0006091) |
Drug Information
No matching records could be found.