Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| AGR2 | 10551 | anterior gradient 2 | 7 | XAG-2, HAG-2, AG2, PDIA17 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24794000 | 2014 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 28 normal tissue and 1068 CRC tumor Stage : - | Immunohistochemistry,chi square test, spearman rank correlations, Kaplan-Meier estimates (Log rank test) and Cox regression | Down-regulation | - | AGR2�is frequently lost in�colorectal�carcinomas and might be a novel independent prognostic factor for overall patient survival. |
| 25655581 | 2015 | Cell line : - Source : - Sample Type : CRC Blood Sample No. of Sample : Blood 30 healthy donors ) and 142 mCRC Stage : - | real time RT-PCR | Up-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Protein disulfide isomerases |
| Description | - | Chromosome | 7 |
| Location | 7p21.3 |
| Start | 16831437 |
| End | 16844738 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 13302 |
| OMIM ID | 606358 |
| HGNC ID | HGNC:328 |
| Unigene ID | Hs.530009 |
| Ensembl ID | ENSG00000106541 |
| PharmGKB ID | PA24625 |
Protein Information
| Protein ID | NP_006399.1 |
|---|---|
| Protein Name | anterior gradient 2 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 175 |
| Uniprot ID | Q9UHC1 |
| Ensembl Protein ID | ENSP00000348020 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 9883 | POM121 | 11448 | NP_742017.1 | yeast 2-hybrid | 16189514 |
| 29117 | BRD7 | 12531 | AAF19526.1 | yeast 2-hybrid | 16169070 |
| 51003 | MED31 | 14382 | NP_057144.1 | yeast 2-hybrid | 16169070 |
| 56893 | UBQLN4 | 5670 | NP_064516.2 | yeast 2-hybrid | 16713569 |
| 60492 | CCDC90B | 14378 | NP_068597.2 | yeast 2-hybrid | 16169070 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd02960 | 47-175 | AGR |
| cl00388 | 47-175 | Thioredoxin_like superfamily |
| pfam13899 | 54-133 | Thioredoxin_7 |
| cd02959 | 50-165 | ERp19 |
| cd01659 | 73-138 | TRX_superfamily |
| cd02951 | 70-123 | SoxW |
Ontology Information
| HPRD ID | 10144 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.