CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
AQP1	358	aquaporin 1 (Colton blood group)	7	CHIP28

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
24649276	2014	Cell line : - Source : - Sample Type : CRC tumor and Normal tissue No. of Sample : 168 Stage : TNM Stage II,III	Tissue microarray	Up-regulation	-	AQP1 may be a promising candidate as a prognostic biomarker for colon cancer. the expression of AQP1 is associated with characteristics of progression of colon cancer, such as lymph node metastasis and lymphovascular invasion and is a poor prognostic factor for advanced colon cancer.

Gene Details

Chromosome 7 - NC_000007.14 (30911800..30925516)
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Gene Type	protein coding
Gene Family	Ion channels / Aquaporins, "Blood group antigens"
Description	Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This gene encodes an aquaporin which functions as a molecular water channel protein. It is a homotetramer with 6 bilayer spanning domains and N-glycosylation sites. The protein physically resembles channel proteins and is abundant in erythrocytes and renal tubes. The gene encoding this aquaporin is a possible candidate for disorders involving imbalance in ocular fluid movement. Several transcript variants encoding different isoforms have been found for this gene.
Chromosome	7
Location	7p14
Start	30911800
End	30925516
Strand	+
Gene Sequence	>gi\|568815591:30911800-30925516 Homo sapiens chromosome 7, GRCh38.p2 Primary Assembly GTGCTCCCCCCGCCCCCCGGCCCTATAAATAGGCCCAGCCCAGGCTGTGGCTCAGCTCTCAGAGGGAATT GAGCACCCGGCAGCGGTCTCAGGCCAAGCCCCCTGCCAGCATGGCCAGCGAGTTCAAGAAGAAGCTCTTC TGGAGGGCAGTGGTGGCCGAGTTCCTGGCCACGACCCTCTTTGTCTTCATCAGCATCGGTTCTGCCCTGG GCTTCAAATACCCGGTGGGGAACAACCAGACGGCGGTCCAGGACAACGTGAAGGTGTCGCTGGCCTTCGG GCTGAGCATCGCCACGCTGGCGCAGAGTGTGGGCCACATCAGCGGCGCCCACCTCAACCCGGCTGTCACA CTGGGGCTGCTGCTCAGCTGCCAGATCAGCATCTTCCGTGCCCTCATGTACATCATCGCCCAGTGCGTGG GGGCCATCGTCGCCACCGCCATCCTCTCAGGCATCACCTCCTCCCTGACTGGGAACTCGCTTGGCCGCAA TGACGTGAGTGGGGTGTCCCTGGGCTTGGGGGGGTTCTAGAATGATGCTGAAAGGCACTGGTTCCATCCT CTGCCCATTGTGCAGATGGGGACACTGAGGAACGGAGAGGACAAGAGGTTGCTGGAGGTCACGTAGAGAG CTGGGGGGAAGAGCTGGGGCTGGAACTCAGCTATGCATGCCTCCCAAAGCCTGTTTTCTGCCAGGCACTG TGGGAAGCTGAGATCCAGAGAATAATGGTCTTGCCAATGTCCCCTGCAGGGCATCTATTATGGGGAATAA GCTTGGCCAGCAGTTCCTCGCCCCTTGGCTGTAGCTTTTTGGCCCTTCTCAGTCCTGCCTGTGCCGCCAG CTCCCTCCTCCTGCAGCCCTGCACCCTGGGGAAACTTTGCCCGCTGTCCCCAGCCACCCTGAACCAAATG CCCAGCCTGTCTGCAGCTGGCTCTGCAAGTGTGTGAGCAGGACTCCCTCAGGGAGCCCCCCATATTCACA CTAGTTTCCAAATAAACCACCTCTAGGAATCAAGAGAAAGGCCCTCTTCCACTCTTTTGCCCCTGAGATT AGACAAAGATAAGGGAGTGAAAACACTCTCTGGGGCTGTTTGAAGGCAGTTTTCCTGGATTACAGTATGG GCTGGGGGGCAAGCGCTGGGCTCCATGGTCTCTAGGCACTGAGAGGTGTGGCGTGTGTGTGCATGTGCGT GTGCGTGTGTGTGTGTGAAGGTGTGTATGTGTGCATGTGTTTGCCAGCATGAGTCTCTGTGCTTGTGTCA ACTGTGTGCATGTTTGTGCTGCTGTGTAAGGGTGTGTGGGGGTGAGTTTGCAACACGTGCCCATGGCTCC TGGCTTGAATGGGGTCTGGACTGGGGTCACTAATGACAAGCAGATGCTGGTGACTGGGTGGCAGCTGTGG AAAAGAATGTCTCCTGGGCTGCTTAGCATGGCAAATTGGCCCTGGTGGCAGCTGCCTGCTGTCCCAGACA CGGCCTTTCCCAGCTCCTCAGACAAGTGCAAACTCAGGCCGGGCTTGGGCCACAGCAGGGGAGGATTTGG CCTGAGAGACTGGGGAAGGCTTGGAGGATGTCTCTGAGGGCCCAAGGGACAGGTGAGCAGGCCTGGGGGT GCCCTTACAGGGAGGGAGAGAAGCCAAGGAGCAGAGAGGAGGACTCGTCTAGAGAGATGAGGCTGGCGGG GCTGTGGGCAGGGCATGTGGGTGTGGGGACGGTGTGGGCCATCTCTGAGGGCGCCTCAGAGATGGCAGAT AGTGATTACAGCAGCTGTCCTCTCGCTTCCCAGCCAAAGTTCAGATCCTGCGGCTGGCAGCCCAGGAGAG GCTAGGTGAAGGTCTGGTGCAGAGGGCAGCTGGCTCAGCCTGGCCATGGGGGGCTTAGCACTTCTGTGTC ACGGTGACACCTCACCCAACCTCCTCTGCAGCCAACCTCTGCTAGGCCCAAGATTGAAGATTAGCTCCGT GGGCTGGAGTTTAGACTTTAGCCAGTTTAGACGTGGCCGCGGGGGATGTACGGGACAGAGCTCAGGCAGG CCACATCAAGCTCTGCCCCCCCAGGCCTCAGTTGCCAGTGGGTGCAGAGCTTGTGGCCTCAGGGAGTTCT GCTGGGTAGGGTCAAGCTCACACTGAAGCTTGGCTGGGTATGATGGGCTGGGGGAGCGTCCCTGTAGGGG AGTGGATGTGATTTCCAGGCTTTCTGGCCCCGTCTCTTCCCTCCCATCTCACAGGGCGGAGCCTCTGCAC CTGCTGGCGAAGGCTTCACCCTCTAGTATGCGCATCCGAGGCAGAGGCGGGAGGGTGGGCCCCTTCTGTG CCATCTGGAACAGAGGCCACACCAGCCTCCCGTGCCCCATTCCCTCCCTGGCCTTCATTTTTTATAGTCA CCCCAATACTTGGGCTGGGCGTGTTGCAAATGGGAGAGAAAGAGGAGCAGCCTAGTGTGGGGTCCGGCCC TGGGCTGAGAGGCAGACACCTGGGTTCAAGACGTGTCCACTGCTAACTTGTTGAGCTTCTTTGGAGCTGC GGACCCTGACCCTCGAGAGGGAACTCAGGTCTTGTGACCTCACAGCCACACCCAGACAGCCAGCTCACTT CATTGCTTTGAGCTTATCACCCATCCCACGAAAGCTGGCTAAGAGCAGCCCAGCAGGGGCAGTGCTGAAC ATAAGGGCGCTTAGCATGATGGTGGGGGCTCAGGCGCTGTCCTGTCCCAACAGTGGAAGGGTGGGGTTCA GGACCTCAACTCTGGGCCTAGAAATAGAGAAGGTACCCCTCTAAGGGCTCCCGTCAGACACTGGCCCTGG AACTGGAGGGGCCTCAGGGGTGGCCTGGATGCCTCAAGAGGAGCAGGGAACAGTCTGGGCAGCAGGTGAC ACACTCTCTTTCATGACCTGGGGTAGGCTCCTGCAGCCTCTCTGGCCCTGAGCCCCAGCCCAGTCAAAAC CTGGGTGGGGCAAGTGGTTGGCATGGAGATTTCCAAGGAAAACAGAGAAAGATGTGGCAGGAAGTGGTTG GGGTGAGTCAGGGGGTGTCCCTTCGGGACATGCTGGGGACAACTTTCTCCTGACTGACTCAGGGCTCAGG ATATGCCCTAGAGAGACCGTGGGCCTCCGTCCAGCCTGCAAGGTCCCGGCTAGTTCTAAGAGCCAAATAC CAATTTTGGCTAAGGGTGAGAGGCTCTGAGGCTGGGGTGGACACTCTCACCTGTCCCTGTCCTAGCTCAG CCACTAACACCATGTGGCATCACACAACAGACTGGCCTGTGTGGCCCTAGTTCCTGTCTATGAGATAGGG ACATAGCAGGGTGTGGCTGGGCTCTGAGAAGTAGGAGATGCTGGTGGACTCAGGATTCCTGGCATTTGCT GGCTTTTTTCATTCTTCTGCTGTCTGGTCTGCTCAGCCGGCTCCCTGCAAGCATGACCAGGGACTGCTGG GTGCTCAATGCAGGGCTGGGTTAGCCCGGCTCCCTCCCGAGAGAAGCCCACAGCCCTAGGTCAAGATAAG CCAGTGCCCAGCTGCCTGTGATATGAAGCAGGAGGCAGATGCGATAAGAGGTGTCAGGGCGGGCCCGGGA ACTTTTGAACTTAAGGGGTGGGAGGGCCAGGAAGGCATCAGGGAGGAGGTTTCGTAGGAGCCTGAATGTG GAGACACTGCAGAGGGAAGGGGCAGAGGGACTGTGTGAGCAAGCACAGGCTAGGAGGAGGTGAGGGCCGT GGTACGGGAGTTGTTGGGTATGGTCAGGCTGGGGGTGCATGGGAGGAGGGTGGTGAGGGCTCAGGATTCG GGCCAGGGGCTGCATCCGGGGGAAGGGGTCTGGATTCCCAGAGCCTGTGATTTCAGCCCGCTGGGCTCAG GCAGAGGGCAAAGCTACCCTCTTCGGGGTCTTCTCCCAGCCCTGCTAATTCCAGGCCTGACTGCTCAAGA AGTGTTTCTACCTGCAGCATCAGGGGCCTGACTGAAGCCCTAAGTTCTCCCCTTTATCCCGTTTTTCTGG GCTTCAGTTTCCCCAGTCATAGAGTGAGAGGCCTCTTCATGCCACCAGTTCTCCCGGGGGTGCTGCTGCC TCCTCCAGAGCTCAGGGGAGGGATGGGGAAAGGAAGGCAGAGTTTCCATGTCCCTGCCCAGCCCGTCCTG CCCAGGGAGGGGCTGGGGGCTGGGTGGTGATGCCACATCTGGGACATATAATTACTGTTTCCGCCAGCCC CAGATGAGGGGGAGGGCACAGAGATGGGGAGCTTTGTGGTGGAGACTTCCCTCACCATGGAAAATCCTGA CGCTGCTTCCCCTTTAGGGACCTCAGAACAGCCCAGCCGGTCCCAGTGTTGCCCACCCTGATGCTTGGCC CTGACTGGGATTTGCCCTGGGAACTCTGAAGGGGCCATGCTTTGAGAGGGGACACGGCCTCCTGGGATAC CTGTCTGAGGGGCTCACCCCCTGCTCACCACTCCCAGGCCACAGCCTCCTGTCACACCTTGCCTTCCCTT CTCCACCCCAGGCAACCTTCTAGCAGCATGAAGTGGCCATTAGCTCACTGCAAGCCAATTCCAGATGGTA CCCCCACTTAGTCTAGGGCCCCCACCCAGCAGGGGCCATGGCCCTTACCTTCTGGAAGCACCAATGAGTC TGGAGTCTCCTGAGTGGCTGGGATCTGAGCCCTCACACCGGGAGGTGAAGGCAGGAAAATGCTGTCCGCG AGGCCCTGCAAGTGGCCAGGATCCCCTCAGTCAGGGCTTCCCCATGGGGATGAGAGGGGCTCCTTGCCCA CATGGAGTGGTGCCCAGGGGGATCATGAGGGGCTGTCTTCACTCAGCCAGGAGCTACAGTTCTGTGGGGT GGGCAGACTCTGAGGCTGAAATCTCCAACTTAAAAGATATCCGGAAAGGCCGGAAAATGCCCCCGGCCCT TCCAGCAGCTCCTTTCAGTGCCTGCAATCTCGCTGTCAGGGCCCCTTGAAAGGCAGATTTCTACTCAGTG TAAAGAAGGTTGTTGTTGATATTGTTGTTGACACGAAGAAGGGGCTGTCTCTAAGTCAATAAGCTCCCTG CCATTAGGGGTGTGCAAGTAGATGCTTTCTGGTGAGGAGGCTGCTTTGGGGGTGCTAGTCTATGCGGGGG TCCAGTGGGGTGGGTGACAGGTTCTGCAGCATAGGCTTTGTGTCATGCTGAGATCAGCAATTCTGATGGC CTGCGGGGGATCCTGTGCTTAGGTTTCTGGATCTGGGGCTGGAGAGTGACCACCCCGATGTGAGGCAGGA GGCACTTTTGGAGACTGCGGGGGCTCGAATCTGGGCCAAGGCCTCCATTTTACTGATGGGGAAACTGAAG CCCACAGAGGCGTGGAGACTTGTCAAGGTGGCACTGCCTCCTAGCCCTTGATTATTCCTGCTGCTCCAAA GTGTACACACATGGCACAAACACAAACATGCACACACATGTGCTCTTACGTGGAGGACACACACACATGG TACACAAAGCACATTCTCAAGACTGGGTGGTCCCACTCAGACTCTGGGACCCAAGGAGGGTTGGGCGGGG ATTCCTCAATGGAGCCTTTTCCTCTCCCTGCCCTGGAGTTAGGAAAAGAAGGAGGGAGGGAGGGAGGAAG CCATTGCTTTGTGTATTGTTTCTTGTCAGGAAGATGAAATGGCTTCTGGGAGCAAATAAAGGCCTTGTTG AGACCTGCTGCTTTCTCACATGGGGGGCTCATTTTTTTCTCTTCTCTTCCCTCTCTAGCTGGTAGTGGCA GCTATGTGGGTGTGTGACACAGGGAGACAGTGAGGCACCCAGAAGTGCCATCAGACATACCAGTGCAAAC ACACAGCACAGCCTCCAGGACCTCATGTCCTGCAGGGATGCCTGTATGATATAGCTGTTCCCAGGGAGGC CGAGGCACTTGGTCAGTACCTCATCAGTTGATGAAAAAGAGTGTGCATTCTCTAATTCAGGGGTACAGGG TTTTCATATTTTTCTGAAGTCAAGCTTGTTAATTATGGGGTTCAAACCCTCCCTGATCATGTTATTGGTA GTTTTCGGCTGCTTCATTTATTCTGTACATTTCTAATAGAAGATTGTTAACATTTTTCACTCTGGTGGTA GGGTGATCCAGTCCTCCTTGTAATTTTGTCAATTTTCCCCTCATTTATTTTTAGGCTATGTTGTTTGGTG CATACAAGTGGGGGATTTTTGCAGTTCCTTTATAGATTTTTATTTTTTTTTTTGAGACGGAGTCTCACTC TGTCGCCCAGGCTGGAGTGCAGTGGCACCATCTCGGCTCACTGCAAGTTCTGCCTCCCGGGTTTATGCCA TTCTCCCACCTCAGCCTCCCGAGTAGCTGGGACCACAGGCCACCACACCCGGCTAATTTTGTTTTTGTAT TTTTAGTAGAGACGGGGTTTAACCGTGTTAGCCAGGATGGTCTCGATCTCCTGACCTTGTGATCCACCCG CCTTGGCTTCTCAGAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCTGGCCAGTTCTTTTATAGATTTT TAAAATGTAATTATTGTGTAATAAACCACTTACAATCTAACAAAAAAGAGAAAGAGGGAGTCAGCCCTGG ACACATGTGGTCATCACAGACACAGCAGACACTTATCTACAAAGACACACAGAGGCACACAAAACCAGGA ATCCCCCCATGTCCACGTGTGAACACCCATGGAGGAGTGACACTCTGGAGCCCACATAGGTCCCCTCACT GCCCAGTGCTGAGTCTTGGAGGCACTGGGGTGGGCAGGGCAGGCCTCGATGTCTCCTATCCCTTGAGAAC GAAAGCTCAGAGCCTCAGTCAGGCCTGGCTCTGGAGCCTGCTCTTCCCCAAGGCCAGGGCACCAGGGTGC CCAGGCCAAGTCAGGGGCCCCATGCCTTGGAAGCCACCCTGGTTGGCCTGTCTATGGGTAGCAGGGAGTG CTTAGAGCACATTGCCTGGAGAGATCATCCCTGGGCTGCCCTAGAGCCAGGACACACTGGCAGCCACAGA ACCACCTTCTGCCAGCTCCCAAGTCCAAGCTGGGAATAGCCAGGTCCCTTGACTGGGCCTAGGAGTGGCC AGCCCATTGACCTGTGAGTGTAGGGTGGCACAGACTATGGGGCAAGGATCCTGGCTTTGCTGCATCCTCC CTGGGCCTCAGCCTCTGCGTCATCATCTCACTGAGCCATCGCACAGGCTGCCCTCTAGGGCTCCCAGAGG CTAATGATTGGCCCATTGTTTCCCAGCTAGAAAGTGAAGAAGACCGCCCTGGGTCCGGAGAGCATCTCTG GAGCCAGGCTGCCCCTAGCAAGGGTGGGAGTTCTAGAAAATTAGCATTCTCTGCCACTTCTATCAGCACA CAGTAAGCCTCCCCTCAGAGGCGTGGGCAGAGAAATGGCAGAGGTCCCCCACTCTGTCTTCACCGAGCTC CCAGGCCAGGAGGAGATGCACCCACATAGGCCGCAGGAAGATTGATTTCCTACAAGATGCACAGAGAATT CAGTGAGGGCATGGTGGGTGGGAGCAGAAGTTAATTCCAGCCAGGGATCTGGGAAGGCTTCTAGGAGCTG GTGGGGTCTGAACTGGGCCTTGAGTAGTGGGCTTACAAGGGCTTAGCACAAAATGGAGAGCTTGTATCTT TCTGACACTTCAGAAGAAATGTGTGGATTATTCTTTCGGTAATACTTGCATTCACAAAACCCAGGGCTGC AGACAAAAGCGGGAAGACAATTGAGAATTGAGAATTGAGAATTGTTCTGATTCTTACTTTTTTTTTTTTT TTTTTGCCTTAATAAGACCTGGGCCAGGCAAAACTACCTGGGGATGTGCAAATATATATGTACATATATA TAAAACAAGTGACTACAATGGGAACTGTCCTTGTTTAAGCAAGTTTTCAAATTTAATGGGTTGTAAACAG TAACGTACATTTGAAGTATTTTACCTGCTCTTTCCTGGACATTGAGTTTCAACAGGCCTTTGAGTGCCCC TTCCAATTCTGAATTATCAAGTGTTTCCAGATGTAAATAATGCAAGTGTATTAGATAGTTGAAGGAAGGT TGTCAGTAGATGTTGAAGCTATCAGGGGAGGCTTCCTGGTGGTAGTGGTAGTGGGTATTGGAGAGGAAGG CTGTCAGCCCATGTGGTTCTCAGCAGTCACGAAGGCACATTCCAGAATTCCCAGGGCAGGTGGCTGACCC CTCCCCTTCCCAAGGACTCAGAGTACAGGGCCTGGAACTATCACCCTCTGCTCTGCCCACTTTGCATGAA AAGCATGTTGTCTTTGGGTAGGGGCTGGGGCTCTCGCACCTGGTTAAGAACCAGAGGAGATGAGCTCTTT CTGGTCACATCTGTGAGGGATGGGGCTGGGAGGGTTCTCCAAGGCGGGAGCCACTTACAGCGATGACTCC ATTAATCATCGGGGAAGGGCTGGTTTCAGGACTTCTGCCAGCTAGCAATTAGGCCAACCCTGGAGAGCAG AAGAGAGAGGAATAGAAGGAGCCACGAGCTTCCTGAGGGCTCAGATACAGAGGGACAGGGGCCTCACAGG TGCAAGTGTGGGTGGGCATCAGGACTAGCCGGGCTGGCCTCACCAGCCTCAACCCCATTCAGCCTGTCCT AACTCTGGGCAGGCTTCTGCCAGCAGCTCCACCCGCCGTCACTCCTTCTGCCTGTCCCCAGATCCTGCAC ACACAATGAGAAGAACCAAAACAAGAGTCACTACCACTGCCCCATCCCTCCTGCGTCGACAACTCTTTCC AAAAGCCCTGAGACGGCCCCTTTGGCCTTTGAACCTCCCAGCTGCTCTGGAGAGCAGGCACGGACAATGA GATCCATTTTGCAGATGGGAAGACTGAAGACCAGAGGGAATAGGCCATGCTCATGGTGCCAGAAAGTAGA AGAGTCAGAACCTGAACACAGGGCTTCTGCCTCTTTGGCCCAACCTTGGGACAGAAAGGGAACTGGGCAT TGGCCAGAGGGCTGGCGGACCTAAGGGATGTAGCCCTGGGGTCCGCCAGGAAAGGCCCAAAGCTGGGGCT GCAAGGCAGGGGAGGGGATGTGAGTCATTCCCTGTAACCCAGGGCTGCAGACAAAGGCGGGAAGAGAATT GTTCTTGTAGGATGGCCTCAGGGTGGGGCTGGGAAAACCTCCAAGGTGTGCCCCCCTACCTTGGATTTTG CAAAATTCTCTATGGCCTTGGAGACACTCCCATATCCTGAGGATGGGAGCTGGGTAGTTTGTCTCCCAGC TGGGAAGTGTTTGGGTGCACCAGCCCTGCCTGGGAGAAGGCAGCCTAAGTGGCCTCAAGTGGGCATCTTT GCAAGTGAGCCTTTGCTGATGTGGTCCATCTCCCCTGTGTGAGTGCACTTAGCCCCTGGGACGGCCACAA AGCATAGTGGAAGGTGCTGGGGCTTCCTGGGGAGGGGTCCTCCGGGGGCAGCTGCATGGGGAGGGCCTTC ATGACCTCACAGCAGCTTCCATTCCCTTCTCTTTCCATGAGTCATGTTTCTAAAAGTGGCCCAGGAGTAA GTGGCAGCCAGACGGTGGTGGCGGGGCCTATCTGGCCAGGCAGAGGGAGGGTGAGGCTGAGGCCAGCAGT GGGGAGGAAGAAGAGAGAAGGAGAGACAGGGAGGGCAGGGCCAGAAGCAATGGGAGACAGGCCTTGGACC AAGGAAAGAGACGGGGTGGAGAAGGAGAGAGAGAGGGTGGAGACAATAGGGAGGCAGGCACAGAGGAGAA AGAGGGGTGGAGGGAGCCAGGACCTCACCGAAGGCCTCCTCAGCCCTGGAATTTAGATGCAGTCGGGCAT GGGGTGGAATGTTCTGGACTTTTGGGTATGAAGCCGTGTCCCCTGCTGGGCCTTCCCACCTTTTTGCATC TCTTCTCCTAGGAGTGCTCCTGACCATCACCTTCATGCCTGGGGCTCGCCCCTTGCCTCTGGTCTTGGTA CCCCAGAATACCCTGGCCTGGATGCAGCTGGATGCAAAGGCCCCAGCTCACCCCAGGCCTCTCCAGCTTC TAGGCAGAGTGGGGCCTGGGTCTAGGCAGGTATTAGGGGCTGGGCTGGAGTTTCATTAACACAGGGGGTG GGTTCAAGGCCTGATTTCCACTACCTGCCGTGTAGGCTTGCCTGGGACCCTGTGATGGGCTCTGAAGGCC CATCTGAGGGTCCGCCCTTCATGCCTGGGCCTGGGAGGCCTGGGTATCCTTGGGGTCCTGGGACACAGTC CCTGCCTACCCTCCTCACCAGTCCTCACCACCTCTCTCCCCTGCAGCTGGCTGATGGTGTGAACTCGGGC CAGGGCCTGGGCATCGAGATCATCGGGACCCTCCAGCTGGTGCTATGCGTGCTGGCTACTACCGACCGGA GGCGCCGTGACCTTGGTGGCTCAGCCCCCCTTGCCATCGGCCTCTCTGTAGCCCTTGGACACCTCCTGGC TGTGAGTCAGGGGCCCTCCCAGATGGAGGTGGGGGAAGGGAGGGCGGGGGCTGGTGGGGTGCCCTGCCAT GGGCAGCCAGTGGGACTCCCGACAGGGCTCTTGCCATTGGGTGGAGGATGGCGGGTCAGCGCTGGGGGCT GGGGGCAGGGTCCTGCCCTGGAGAGGAGCACAGGGACCTCCTGCCCAGCTTGGGGTCAGCACTCCTCTTT CCCTGGGTCTCATTGTCCCCCACCCTGATTGTTCTCTTTCTCCCTCCAACCTCTCCCTCCTCTCACTCTC TCTTCACCTATGACTCTCTGCCTTCGCCCCTCCCTCTGTTTCTTTCCCTCACAGATTGACTACACTGGCT GTGGGATTAACCCTGCTCGGTCCTTTGGCTCCGCGGTGATCACACACAACTTCAGCAACCACTGGGTAGG AGACCCACGGGGGGTGGGGTGGGAAGCTTTGGTGTCCCATGGTAAGCCTGACCCCACCCTCACAGTGTCC CTTCCTGTTCTGGAGGCTCTGGGAGACAGCCAGAGGACAGGAAATCAGGAAACTGAGGCCTGCCATGTAG AGGCAGGCTGGGGGTCACACTGCCAGCACTTTCAGGCCTAGTCTCTGCCCTCCCAGCTCGGCCCTGCCCC ATGCTGCCTGGCCTCCAGGTCTTCCCAGCTGCGTGGTTAAAAGTGGGGCTCCAAATCCTGGCTCAGCCAC TTTCGGGTTTAGCATGACCTTGCGCAGTGTGCTTGAGCTTTGGTTTCCTGAGCTGCGGAGGGGGATATGG TGGTGCCCACCTCTCAGGGTGGCCGAGAAGAGGAAAGGGCTCACTCCCCATCTGTAAACTGAGCTCAACA CAGAGGAGGCGCTCAGTGGATTTTAGCTCTTATGGTTGTGGATGTGGATGTGCTAGGCCAGCTTTGCATT AGACAATGGTCTCTGGGGCCCTTCCAAAGCTGGGAGTGTGGGGGCAGTGGCCTTCCTCAAGAAGGGGCTG CTACTGCCCATGCCTGAGCTGGGCCCCACAGAGGCAAGGAGTTGACCCTACCACGTACTCTGGCCTGGGC CGGTTCTGAGGGGCACCGGAATCATGATGTTAGGATTTGGCTCTCCTACCTGCCTCCATCCCAGGTGGGA AAAACCTGTCCAACGGGGTGGTGGGCTGTGGGGTAACCTAGGGAACGCTTCCCAGGGGCTTTTGAGTGGA GCCCTCTGAACACACCTGCTCTGTTCCTAGATTTTCTGGGTGGGGCCATTCATCGGGGGAGCCCTGGCTG TACTCATCTACGACTTCATCCTGGCCCCACGCAGCAGTGACCTCACAGACCGCGTGAAGGTGTGGACCAG CGGCCAGGTGGAGGAGTATGACCTGGATGCCGACGACATCAACTCCAGGGTGGAGATGAAGCCCAAATAG AAGGGGTCTGGCCCGGGCATCCACGTAGGGGGCAGGGGCAGGGGCGGGCGGAGGGAGGGGAGGGGTGAAA TCCATACTGTAGACACTCTGACAAGCTGGCCAAAGTCACTTCCCCAAGATCTGCCAGACCTGCATGGTCA AGCCTCTTATGGGGGTGTTTCTATCTCTTTCTTTCTCTTTCTGTTTCCTGGCCTCAGAGCTTCCTGGGGA CCAAGATTTACCAATTCACCCACTCCCTTGAAGTTGTGGAGGAGGTGAAAGAAAGGGACCCACCTGCTAG TCGCCCCTCAGAGCATGATGGGAGGTGTGCCAGAAAGTCCCCCCTCGCCCCAAAGTTGCTCACCGACTCA CCTGCGCAAGTGCCTGGGATTCTACCGTAATTGCTTTGTGCCTTTGGGCACGGCCCTCCTTCTTTTCCTA ACATGCACCTTGCTCCCAATGGTGCTTGGAGGGGGAAGAGATCCCAGGAGGTGCAGTGGAGGGGGCAAGC TTTGCTCCTTCAGTTCTGCTTGCTCCCAAGCCCCTGACCCGCTCGGACTTACTGCCTGACCTTGGAATCG TCCCTATATCAGGGCCTGAGTGACCTCCTTCTGCAAAGTGGCAGGGACCGGCAGAGCTCTACAGGCCTGC AGCCCCTAAGTGCAAACACAGCATGGGTCCAGAAGACGTGGTCTAGACCAGGGCTGCTCTTTCCACTTGC CCTGTGTTCTTTCCCCAGGGGCATGACTGTCGCCACACGCCTCTGTGTACATGTGTGCAGAGCAGACAGG CTACAAAGCAGAGATCGACAGACAGCCAGGTAGTTGGAACTTTCTGTTCCCTATGGAGAGGCTTCCCTAC ACAGGGCCTGCTATTGCAGAATGAAGCCATTTAGAGGGTGAAGGAGAAATACCCATGTTACTTCTCTGAG TTTTAGTTGGTCTTTCCATCTATCACTGCATTATCTTGCTCATTCTTCAGTTCTCTACTCCCTCTTGTCA GTGTAGACACAGGTCACCATTATGCTGGTGTATGTTTATCAAAGAGCACTTGAGCTGTCTGAAGCCCAAA GCCTGAGGACAGAAAGACCCTGATGCAGGTCAGCCCATGGAGGCAGATGCCCTTGCTGGGCCTGGGGGTT TTCCAAGCCCTCAGCTGGTCCTGACCAGGATGGAGCAAGCTCTTCCCTTGCTCATGAGCTCCTGATCAGA GGCATTTGAGCAGCTGAATAACCTGCACAGGCTTGCTGTATGACCCCTGGCCACAGCCTTCCCTCTGCAT TGACCTGGAGGGGAGAGGTCAGCCTTGACCTAATGAGGTAGCTATAGTTGCAGCCCAAGGACAGTTCAGA GATCAGGATCAGCTTTGAAGGCTGGATTCTATCTACATAAGTCCTTTCAATTCCACCAGGGCCAGAGCAG CTCCACCACTGTGCACTTAGCCATGATGGCAACAGAAACCAAGAGACACAATTACGCAGGTATTTAGAAG CAGAGGGACAACCAGAAGGCCCTTAACTATCACCAGTGCATCACATCTGCACACTCTCTTCTCCATTCCC TAGCAGGAACTTCTAGCTCATTTAACAGATAAAGAAACTGAGGCCCACGGTTTCAGCTAGACAATGATTT GGCCAGGCCTAGTAACCAAGGCCCTGTCTCTGGCTACTCCCTGGACCACGAGGCTGATTCCTCTCATTTC CAGCTTCTCAGTTTCTGCCTGGGCAATGGCCAGGGGCCAGGAGTGGGGAGAGTTGTGATGGAGGGGAGAG GGGTCACACCCACCCCCTGCCTGGTTCTAGGCTGCTGCACACCAAGGCCCTGCATCTGTCTGCTCTGCAT ATATGTCTCTTTGGAGTTGGAATTTCATTATATGTTAAGAAAATAAAGGAAAATGACTTGTAAGGTC Download Select all
Length	13717
OMIM ID	107776
HGNC ID	HGNC:633
Unigene ID	Hs.76152
Ensembl ID	ENSG00000240583
PharmGKB ID	-

mRNA Information

mRNA ID	NM_198098.2
Exon	join(1..494,10267..10431,10765..10845,11651..13717)
mRNA Sequence	>358 TAAAAGTGGCCCAGGAGAGTGCTCCTGACCATCACCTTCATGCCTGGGGCTCGCCCCTTGCCTC TGGTCTTGGTACCCCAGAATACCCTGGCCTGGATGCAGCTGGATGCAAAGGCCCCAGCTCACCC CAGGCCTCTCCAGCTTCTAGGCAGAGTGGGGCCTGGGTCTAGGCAGCTGGCTGATGGTGTGAAC TCGGGCCAGGGCCTGGGCATCGAGATCATCGGGACCCTCCAGCTGGTGCTATGCGTGCTGGCTA CTACCGACCGGAGGCGCCGTGACCTTGGTGGCTCAGCCCCCCTTGCCATCGGCCTCTCTGTAGC CCTTGGACACCTCCTGGCTATTGACTACACTGGCTGTGGGATTAACCCTGCTCGGTCCTTTGGC TCCGCGGTGATCACACACAACTTCAGCAACCACTGGATTTTCTGGGTGGGGCCATTCATCGGGG GAGCCCTGGCTGTACTCATCTACGACTTCATCCTGGCCCCACGCAGCAGTGACCTCACAGACCG CGTGAAGGTGTGGACCAGCGGCCAGGTGGAGGAGTATGACCTGGATGCCGACGACATCAACTCC AGGGTGGAGATGAAGCCCAAATAGAAGGGGTCTGGCCCGGGCATCCACGTAGGGGGCAGGGGCA GGGGCGGGCGGAGGGAGGGGAGGGGTGAAATCCATACTGTAGACACTCTGACAAGCTGGCCAAA GTCACTTCCCCAAGATCTGCCAGACCTGCATGGTCAAGCCTCTTATGGGGGTGTTTCTATCTCT TTCTTTCTCTTTCTGTTTCCTGGCCTCAGAGCTTCCTGGGGACCAAGATTTACCAATTCACCCA CTCCCTTGAAGTTGTGGAGGAGGTGAAAGAAAGGGACCCACCTGCTAGTCGCCCCTCAGAGCAT GATGGGAGGTGTGCCAGAAAGTCCCCCCTCGCCCCAAAGTTGCTCACCGACTCACCTGCGCAAG TGCCTGGGATTCTACCGTAATTGCTTTGTGCCTTTGGGCACGGCCCTCCTTCTTTTCCTAACAT GCACCTTGCTCCCAATGGTGCTTGGAGGGGGAAGAGATCCCAGGAGGTGCAGTGGAGGGGGCAA GCTTTGCTCCTTCAGTTCTGCTTGCTCCCAAGCCCCTGACCCGCTCGGACTTACTGCCTGACCT TGGAATCGTCCCTATATCAGGGCCTGAGTGACCTCCTTCTGCAAAGTGGCAGGGACCGGCAGAG CTCTACAGGCCTGCAGCCCCTAAGTGCAAACACAGCATGGGTCCAGAAGACGTGGTCTAGACCA GGGCTGCTCTTTCCACTTGCCCTGTGTTCTTTCCCCAGGGGCATGACTGTCGCCACACGCCTCT GTGTACATGTGTGCAGAGCAGACAGGCTACAAAGCAGAGATCGACAGACAGCCAGGTAGTTGGA ACTTTCTGTTCCCTATGGAGAGGCTTCCCTACACAGGGCCTGCTATTGCAGAATGAAGCCATTT AGAGGGTGAAGGAGAAATACCCATGTTACTTCTCTGAGTTTTAGTTGGTCTTTCCATCTATCAC TGCATTATCTTGCTCATTCTTCAGTTCTCTACTCCCTCTTGTCAGTGTAGACACAGGTCACCAT TATGCTGGTGTATGTTTATCAAAGAGCACTTGAGCTGTCTGAAGCCCAAAGCCTGAGGACAGAA AGACCCTGATGCAGGTCAGCCCATGGAGGCAGATGCCCTTGCTGGGCCTGGGGGTTTTCCAAGC CCTCAGCTGGTCCTGACCAGGATGGAGCAAGCTCTTCCCTTGCTCATGAGCTCCTGATCAGAGG CATTTGAGCAGCTGAATAACCTGCACAGGCTTGCTGTATGACCCCTGGCCACAGCCTTCCCTCT GCATTGACCTGGAGGGGAGAGGTCAGCCTTGACCTAATGAGGTAGCTATAGTTGCAGCCCAAGG ACAGTTCAGAGATCAGGATCAGCTTTGAAGGCTGGATTCTATCTACATAAGTCCTTTCAATTCC ACCAGGGCCAGAGCAGCTCCACCACTGTGCACTTAGCCATGATGGCAACAGAAACCAAGAGACA CAATTACGCAGGTATTTAGAAGCAGAGGGACAACCAGAAGGCCCTTAACTATCACCAGTGCATC ACATCTGCACACTCTCTTCTCCATTCCCTAGCAGGAACTTCTAGCTCATTTAACAGATAAAGAA ACTGAGGCCCACGGTTTCAGCTAGACAATGATTTGGCCAGGCCTAGTAACCAAGGCCCTGTCTC TGGCTACTCCCTGGACCACGAGGCTGATTCCTCTCATTTCCAGCTTCTCAGTTTCTGCCTGGGC AATGGCCAGGGGCCAGGAGTGGGGAGAGTTGTGATGGAGGGGAGAGGGGTCACACCCACCCCCT GCCTGGTTCTAGGCTGCTGCACACCAAGGCCCTGCATCTGTCTGCTCTGCATATATGTCTCTTT GGAGTTGGAATTTCATTATATGTTAAGAAAATAAAGGAAAATGACTTGTAAGGTC Download Select all
Length	2487

CDS Information

Location	join(111..494,10267..10431,10765..10845,11651..11830)
CDS Sequence	>lcl\|NM_001185060.1_cds_NP_001171989.1_1 [gene=AQP1] [protein=aquaporin-1 isoform 2] [protein_id=NP_001171989.1] [location=40..600] ATGCCTGGGGCTCGCCCCTTGCCTCTGGTCTTGGTACCCCAGAATACCCTGGCCTGGATGCAGCTGGATG CAAAGGCCCCAGCTCACCCCAGGCCTCTCCAGCTTCTAGGCAGAGTGGGGCCTGGGTCTAGGCAGCTGGC TGATGGTGTGAACTCGGGCCAGGGCCTGGGCATCGAGATCATCGGGACCCTCCAGCTGGTGCTATGCGTG CTGGCTACTACCGACCGGAGGCGCCGTGACCTTGGTGGCTCAGCCCCCCTTGCCATCGGCCTCTCTGTAG CCCTTGGACACCTCCTGGCTATTGACTACACTGGCTGTGGGATTAACCCTGCTCGGTCCTTTGGCTCCGC GGTGATCACACACAACTTCAGCAACCACTGGATTTTCTGGGTGGGGCCATTCATCGGGGGAGCCCTGGCT GTACTCATCTACGACTTCATCCTGGCCCCACGCAGCAGTGACCTCACAGACCGCGTGAAGGTGTGGACCA GCGGCCAGGTGGAGGAGTATGACCTGGATGCCGACGACATCAACTCCAGGGTGGAGATGAAGCCCAAATA G Download Select all
CCDS ID	CCDS5431.1

Protein Information

Protein ID	NP_932766.1
Protein Name	aquaporin 1 (Colton blood group)
Molecular Wt. (Da)	28395
Protein Sequence	>358 MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDNVKVSLAFGLSIATLA QSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLGRND LADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGIN PARSFGSAVITHNFSNHWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLD ADDINSRVEMKPK Download Select all
Length	269
Uniprot ID	P10912
Ensembl Protein ID	ENSP00000230882

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
N	Glycosylation	42
S	Phosphorylation	262
S	Phosphorylation	262

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
4188	MDFI	7280	NP_005577.1	yeast 2-hybrid	16189514
7205	TRIP6	4242	NP_003293.2	yeast 2-hybrid	16189514
11007	CCDC85B	16101	NP_006839.2	yeast 2-hybrid	16189514
30008	EFEMP2	5221	NP_058634.3	yeast 2-hybrid	16189514
79734	KCTD17	7764	NP_078957.2	yeast 2-hybrid	16189514
83755	KRTAP4-12	13941	NP_114060.1	yeast 2-hybrid	16189514

Pathway Information

Pathway Name	Pathway ID
Bile secretion	hsa04976
Proximal tubule bicarbonate reclamation	hsa04964
Renin secretion	hsa04924

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd00333	12-230	MIP
cl00200	12-230	MIP superfamily
pfam00230	4-227	MIP
TIGR00861	16-227	MIP
COG0580	15-233	GlpF
PLN00166	12-227	PLN00166
PLN00027	12-230	PLN00027
PRK05420	12-235	PRK05420
PLN00167	12-240	PLN00167
PTZ00016	8-233	PTZ00016
PLN00182	14-230	PLN00182
PLN00184	10-230	PLN00184
PLN00183	12-230	PLN00183
PLN00026	12-227	PLN00026
COG0580	10-111	GlpF

Ontology Information

HPRD ID	1311
Molecular Class	Water channel
Molecular Function	Transcription factor activity (GO:0003700)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report

Drug Information

Uniprot ID DrugBank ID Name Type
P29972 DB00819 Acetazolamide SmallMoleculeDrug

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO