Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| ARAF | 369 | A-Raf proto-oncogene, serine/threonine kinase | X | - |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 14688025 | 2004 | Cell line : - Source : Department of Surgery, Ryhov County Hospital, Jonkoping, Sweden Sample Type : CRC Tumor No. of Sample : 130 Stage : - | real time RT-PCR,DNA isolation,PCR amplification of genomic DNA,Mutation analysis,DNA sequencing and MSI analysis | Mutation | - | One germline exonic and nine germline intronic genetic variants were found in the ARAF and RAF-1 genes. 130 primary colorectal cancer tumors and correlated with clinico-pathological and mutational data. |
| 15676015 | 2005 | Cell line : - Source : - Sample Type : CRC, gastric carcinomas, ovarian tumors and acute leukemias tumor No. of Sample : 323 Stage : - | - | Mutation | - | ARAF gene is rarely mutated in human cancers. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2012] | Chromosome | X |
| Location | Xp11.3-p11 |
| Start | 47420499 |
| End | 47431320 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 10822 |
| OMIM ID | 311010 |
| HGNC ID | HGNC:646 |
| Unigene ID | Hs.446641 |
| Ensembl ID | ENSG00000078061 |
| PharmGKB ID | PA24928 |
mRNA Information
| mRNA ID | NM_001256196.1 |
|---|---|
| Exon | join(1..152,1810..1964,2127..2230,3698..3800,3886..4040, 4144..4251,5540..5681,5785..5812,5887..6032,6131..6333, 7619..7795,7888..7934,8440..8558,8794..8925,9779..9913, 10224..10822) | mRNA Sequence | Download Select all |
| Length | 2571 |
Protein Information
| Protein ID | NP_001243125.1 |
|---|---|
| Protein Name | A-Raf proto-oncogene, serine/threonine kinase |
| Molecular Wt. (Da) | 67795 |
| Protein Sequence | Download Select all |
| Length | 609 |
| Uniprot ID | P16455 |
| Ensembl Protein ID | ENSP00000302111 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| S | Phosphorylation | 582;- |
| T | Phosphorylation | 181;- |
| S | Phosphorylation | 186;- |
| S | Phosphorylation | 212 |
| S | Phosphorylation | 214 |
| T | Phosphorylation | 215 |
| S | Phosphorylation | 222 |
| T | Phosphorylation | 223 |
| T | Phosphorylation | 224 |
| S | Phosphorylation | 580 |
| S | Phosphorylation | 257 |
| T | Phosphorylation | 253 |
| S | Phosphorylation | 259 |
| S | Phosphorylation | 269 |
| S | Phosphorylation | 272 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 1373 | CPS1 | 1995 | NP_001116105.1 | yeast 2-hybrid | 12620389 |
| 1460 | CSNK2B | 278 | NP_001311.3 | in vitro;yeast 2-hybrid | 9042965 |
| 3265 | HRAS | 1813 | NP_005334.1 | yeast 2-hybrid | 12620389 |
| 5295 | PIK3R1 | 1381 | NP_852664.1 | in vitro;in vivo | 1 181 200 010 967 100 |
| 5315 | PKM2 | 1529 | NP_872270.1 | yeast 2-hybrid | 12620389 |
| 5604 | MAP2K1 | 1469 | NP_002746.1 | in vitro | 8 157 000 862 172 980 000 000 000 000 |
| 5876 | RABGGTB | 1532 | NP_004573.2 | yeast 2-hybrid | 12620389 |
| 6237 | RRAS | 1299 | NP_006261.1 | in vitro;yeast 2-hybrid | 10848612 |
| 59349 | KLHL12 | 13925 | NP_067646.1 | yeast 2-hybrid | 16189514 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Acute myeloid leukemia | hsa05221 |
| Alcoholism | hsa05034 |
| Bladder cancer | hsa05219 |
| Chronic myeloid leukemia | hsa05220 |
| Colorectal cancer | hsa05210 |
| Endometrial cancer | hsa05213 |
| ErbB signaling pathway | hsa04012 |
| FoxO signaling pathway | hsa04068 |
| Glioma | hsa05214 |
| Hepatitis C | hsa05160 |
| Insulin signaling pathway | hsa04910 |
| Long-term depression | hsa04730 |
| Long-term potentiation | hsa04720 |
| Melanoma | hsa05218 |
| Natural killer cell mediated cytotoxicity | hsa04650 |
| Non-small cell lung cancer | hsa05223 |
| Pancreatic cancer | hsa05212 |
| Pathways in cancer | hsa05200 |
| Progesterone-mediated oocyte maturation | hsa04914 |
| Prostate cancer | hsa05215 |
| Proteoglycans in cancer | hsa05205 |
| Regulation of actin cytoskeleton | hsa04810 |
| Renal cell carcinoma | hsa05211 |
| Serotonergic synapse | hsa04726 |
| Vascular smooth muscle contraction | hsa04270 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd14150 | 309-573 | STKc_A-Raf |
| cl21453 | 309-573 | PKc_like superfamily |
| cd01816 | 20-91 | Raf_RBD |
| cl00155 | 20-91 | UBQ superfamily |
| cd00029 | 99-144 | C1 |
| cl00040 | 99-144 | C1 superfamily |
| cd14062 | 316-568 | STKc_Raf |
| cd14149 | 297-579 | STKc_C-Raf |
| cd14151 | 303-574 | STKc_B-Raf |
| cd13999 | 316-564 | STKc_MAP3K-like |
| cd14063 | 309-572 | PK_KSR |
| cd00192 | 314-568 | PTKc |
| cd14153 | 309-576 | PK_KSR2 |
| cd14152 | 309-584 | STKc_KSR1 |
| cd05068 | 303-560 | PTKc_Frk_like |
| cd14061 | 316-568 | STKc_MLK |
| cd14014 | 311-558 | STKc_PknB_like |
| cd06606 | 314-571 | STKc_MAPKKK |
| cd14059 | 316-569 | STKc_MAP3K12_13 |
| cd00180 | 316-502 | PKc |
| cd05148 | 303-560 | PTKc_Srm_Brk |
| cd14066 | 316-570 | STKc_IRAK |
| cd05122 | 309-564 | PKc_STE |
| cd08215 | 313-567 | STKc_Nek |
| cd05034 | 314-560 | PTKc_Src_like |
| cd14058 | 316-575 | STKc_TAK1 |
| cd05072 | 303-568 | PTKc_Lyn |
| cd05039 | 303-570 | PTKc_Csk_like |
| cd05117 | 311-546 | STKc_CAMK |
| cd05067 | 303-568 | PTKc_Lck_Blk |
| cd05033 | 305-568 | PTKc_EphR |
| cd05070 | 303-568 | PTKc_Fyn |
| cd14147 | 309-570 | STKc_MLK3 |
| cd14203 | 314-568 | PTKc_Src_Fyn_like |
| cd05069 | 303-568 | PTKc_Yes |
| cd14148 | 316-570 | STKc_MLK2 |
| cd05038 | 312-570 | PTKc_Jak_rpt2 |
| cd05071 | 303-568 | PTKc_Src |
| cd14060 | 317-568 | STKc_MLTK |
| cd05032 | 303-568 | PTKc_InsR_like |
| cd14003 | 312-565 | STKc_AMPK-like |
| cd14145 | 304-564 | STKc_MLK1 |
| cd13978 | 316-560 | STKc_RIP |
| cd05055 | 303-568 | PTKc_PDGFR |
| cd05073 | 303-568 | PTKc_Hck |
| cd05041 | 314-567 | PTKc_Fes_like |
| cd14146 | 316-564 | STKc_MLK4 |
| cd13979 | 306-558 | STKc_Mos |
| cd14064 | 316-568 | PKc_TNNI3K |
| cd05066 | 305-570 | PTKc_EphR_A |
| cd05063 | 304-570 | PTKc_EphR_A2 |
| cd05057 | 304-572 | PTKc_EGFR_like |
| cd05053 | 303-574 | PTKc_FGFR |
| cd05065 | 305-570 | PTKc_EphR_B |
| cd06627 | 311-558 | STKc_Cdc7_like |
| cd14205 | 310-571 | PTKc_Jak2_rpt2 |
| cd05059 | 307-567 | PTKc_Tec_like |
| cd06613 | 311-558 | STKc_MAP4K3_like |
| cd14158 | 315-568 | STKc_IRAK4 |
| cd05040 | 314-563 | PTKc_Ack_like |
| cd08529 | 309-566 | STKc_FA2-like |
| cd06612 | 307-571 | STKc_MST1_2 |
| cd05083 | 303-568 | PTKc_Chk |
| cd13983 | 316-564 | STKc_WNK |
| cd05113 | 305-568 | PTKc_Btk_Bmx |
| cd13996 | 313-567 | STKc_EIF2AK |
| cd14009 | 316-547 | STKc_ATG1_ULK_like |
| cd06614 | 313-564 | STKc_PAK |
| cd05048 | 304-563 | PTKc_Ror |
| cd05052 | 303-568 | PTKc_Abl |
| cd05036 | 304-568 | PTKc_ALK_LTK |
| cd06632 | 316-565 | STKc_MEKK1_plant |
| cd14007 | 311-565 | STKc_Aurora |
| cd14002 | 311-509 | STKc_STK36 |
| cd05082 | 303-568 | PTKc_Csk |
| cd05084 | 314-563 | PTKc_Fes |
| cd05112 | 305-564 | PTKc_Itk |
| cd05081 | 316-571 | PTKc_Jak3_rpt2 |
| cd06628 | 316-564 | STKc_Byr2_like |
| cd14056 | 314-503 | STKc_TGFbR_I |
| cd08220 | 316-565 | STKc_Nek8 |
| cd14155 | 316-574 | PKc_TESK |
| cd05061 | 303-574 | PTKc_InsR |
| cd05046 | 305-568 | PTK_CCK4 |
| cd05079 | 309-570 | PTKc_Jak1_rpt2 |
| cd08530 | 311-566 | STKc_CNK2-like |
| cd05044 | 314-568 | PTKc_c-ros |
| cd14154 | 316-570 | STKc_LIMK |
| cd14065 | 316-503 | PKc_LIMK_like |
| cd14026 | 313-577 | STKc_RIP2 |
| cd08222 | 312-566 | STKc_Nek11 |
| cd14080 | 311-565 | STKc_TSSK-like |
| cd13997 | 311-566 | PKc_Wee1_like |
| cd06626 | 311-571 | STKc_MEKK4 |
| cd14099 | 314-565 | STKc_PLK |
| cd05058 | 316-570 | PTKc_Met_Ron |
| cd05051 | 304-563 | PTKc_DDR |
| cd08225 | 311-564 | STKc_Nek5 |
| cd05106 | 303-568 | PTKc_CSF-1R |
| cd05099 | 303-577 | PTKc_FGFR4 |
| cd05060 | 314-563 | PTKc_Syk_like |
| cd08223 | 309-564 | STKc_Nek4 |
| cd06633 | 281-573 | STKc_TAO3 |
| cd05123 | 316-557 | STKc_AGC |
| cd06623 | 308-521 | PKc_MAPKK_plant_like |
| cd05056 | 303-568 | PTKc_FAK |
| cd14027 | 319-563 | STKc_RIP1 |
| cd08218 | 313-564 | STKc_Nek1 |
| cd05098 | 303-574 | PTKc_FGFR1 |
| cd06605 | 308-565 | PKc_MAPKK |
| pfam02196 | 20-91 | RBD |
| cd05054 | 303-563 | PTKc_VEGFR |
| cd06630 | 316-574 | STKc_MEKK1 |
| cd06609 | 308-512 | STKc_MST3_like |
| cd05064 | 304-563 | PTKc_EphR_A10 |
| cd14162 | 311-564 | STKc_TSSK4-like |
| cd06608 | 306-565 | STKc_myosinIII_N_like |
| cd14664 | 316-516 | STK_BAK1_like |
| cd14008 | 316-546 | STKc_LKB1_CaMKK |
| cd05108 | 308-572 | PTKc_EGFR |
| cd05111 | 307-512 | PTK_HER3 |
| cd14202 | 316-560 | STKc_ULK1 |
| cd06629 | 316-558 | STKc_Bck1_like |
| cd05080 | 310-571 | PTKc_Tyk2_rpt2 |
| cd05049 | 304-563 | PTKc_Trk |
| cd05085 | 316-563 | PTKc_Fer |
| cd05118 | 311-565 | STKc_CMGC |
| cd05109 | 308-572 | PTKc_HER2 |
| cd05115 | 309-574 | PTKc_Zap-70 |
| cd01760 | 20-91 | RBD |
| cd05110 | 308-572 | PTKc_HER4 |
| cd14221 | 316-574 | STKc_LIMK1 |
| cd14156 | 316-574 | PKc_LIMK_like_unk |
| cd06646 | 306-502 | STKc_MAP4K5 |
| cd08217 | 311-577 | STKc_Nek2 |
| cd06607 | 313-558 | STKc_TAO |
| cd05091 | 304-563 | PTKc_Ror2 |
| cd05104 | 303-568 | PTKc_Kit |
| cd13998 | 316-502 | STKc_TGFbR-like |
| cd05581 | 314-510 | STKc_PDK1 |
| cd06634 | 313-575 | STKc_TAO2 |
| cd13992 | 311-563 | PK_GC |
| cd05101 | 303-574 | PTKc_FGFR2 |
| cd06631 | 316-565 | STKc_YSK4 |
| cd05114 | 307-567 | PTKc_Tec_Rlk |
| cd14047 | 313-503 | STKc_EIF2AK2_PKR |
| cd05045 | 310-570 | PTKc_RET |
| cd06610 | 308-558 | STKc_OSR1_SPAK |
| cd06641 | 306-585 | STKc_MST3 |
| cd06611 | 305-510 | STKc_SLK_like |
| cd06635 | 301-576 | STKc_TAO1 |
| cd05062 | 303-568 | PTKc_IGF-1R |
| cd14000 | 316-563 | STKc_LRRK |
| cd06625 | 314-558 | STKc_MEKK3_like |
| cd14093 | 334-546 | STKc_PhKG |
| cd06917 | 308-510 | STKc_NAK1_like |
| cd14057 | 322-568 | PK_ILK |
| cd14121 | 315-546 | STKc_ULK3 |
| cd14069 | 308-509 | STKc_Chk1 |
| cd08224 | 311-558 | STKc_Nek6_7 |
| cd05047 | 316-571 | PTKc_Tie |
| cd05074 | 305-570 | PTKc_Tyro3 |
| smart00455 | 20-91 | RBD |
| cd05107 | 303-570 | PTKc_PDGFR_beta |
| cd05075 | 309-575 | PTKc_Axl |
| cd14159 | 316-533 | STKc_IRAK1 |
| cd06645 | 306-531 | STKc_MAP4K3 |
| cd05100 | 303-589 | PTKc_FGFR3 |
| cd14098 | 311-564 | STKc_Rad53_Cds1 |
| cd06637 | 306-564 | STKc_TNIK |
| cd05050 | 304-568 | PTKc_Musk |
| cd14222 | 316-570 | STKc_LIMK2 |
| cd06653 | 307-565 | STKc_MEKK3_like_u1 |
| cd14054 | 316-549 | STKc_BMPR2_AMHR2 |
| cd14042 | 333-572 | PK_GC-A_B |
| cd14142 | 309-502 | STKc_ACVR1_ALK1 |
| cd14096 | 309-546 | STKc_RCK1-like |
| cd06647 | 306-557 | STKc_PAK_I |
| cd06624 | 316-565 | STKc_ASK |
| cd14006 | 316-510 | STKc_MLCK-like |
| cd14053 | 314-504 | STKc_ACVR2 |
| cd14010 | 312-511 | STKc_ULK4 |
| cd05578 | 311-509 | STKc_Yank1 |
| cd13985 | 309-509 | STKc_GAK_like |
| cd14192 | 302-509 | STKc_MLCK3 |
| cd05090 | 304-563 | PTKc_Ror1 |
| cd05103 | 303-573 | PTKc_VEGFR2 |
| cd05102 | 303-571 | PTKc_VEGFR3 |
| cd06644 | 304-564 | STKc_STK10 |
| cd14143 | 315-549 | STKc_TGFbR1_ACVR1b_ACVR1c |
| cd06636 | 306-508 | STKc_MAP4K4_6_N |
| cd06643 | 302-502 | STKc_SLK |
| cd14201 | 316-557 | STKc_ULK2 |
| cd06655 | 306-582 | STKc_PAK2 |
| cd14663 | 311-566 | STKc_SnRK3 |
| cd13982 | 314-564 | STKc_IRE1 |
| cd07840 | 311-505 | STKc_CDK9_like |
| cd14220 | 314-549 | STKc_BMPR1a |
| cd14097 | 314-509 | STKc_STK33 |
| cd06616 | 303-566 | PKc_MKK4 |
| cd05035 | 310-568 | PTKc_TAM |
| cd14189 | 334-565 | STKc_PLK3 |
| cd13989 | 316-511 | STKc_IKK |
| cd14046 | 308-519 | STKc_EIF2AK4_GCN2_rpt2 |
| cd07830 | 311-564 | STKc_MAK_like |
| cd14084 | 314-519 | STKc_Chk2 |
| cd05580 | 308-509 | STKc_PKA_like |
| cd14072 | 311-509 | STKc_MARK |
| cd14120 | 316-561 | STKc_ULK1_2-like |
| cd06640 | 313-564 | STKc_MST4 |
| cd14081 | 311-546 | STKc_BRSK1_2 |
| cd06642 | 313-564 | STKc_STK25 |
| cd05089 | 303-563 | PTKc_Tie1 |
| cd14204 | 314-575 | PTKc_Mer |
| cd05043 | 305-565 | PTK_Ryk |
| cd14033 | 316-557 | STKc_WNK4 |
| cd13993 | 311-573 | STKc_Pat1_like |
| cd14073 | 311-509 | STKc_NUAK |
| cd05582 | 314-509 | STKc_RSK_N |
| cd06656 | 306-582 | STKc_PAK3 |
| cd06654 | 306-582 | STKc_PAK1 |
| cd14119 | 316-563 | STKc_LKB1 |
| cd14206 | 313-522 | PTKc_Aatyk3 |
| cd14095 | 311-557 | STKc_DCKL |
| cd14055 | 314-561 | STKc_TGFbR2_like |
| cd05088 | 308-567 | PTKc_Tie2 |
| cd14144 | 314-502 | STKc_BMPR1 |
| cd14164 | 312-563 | STKc_TSSK6-like |
| cd05092 | 316-555 | PTKc_TrkA |
| cd05105 | 303-570 | PTKc_PDGFR_alpha |
| cd08528 | 309-558 | STKc_Nek10 |
| cd14103 | 316-509 | STKc_MLCK |
| cd14025 | 314-575 | STKc_RIP4_like |
| cd05116 | 314-573 | PTKc_Syk |
| cd14187 | 347-509 | STKc_PLK1 |
| cd05577 | 316-509 | STKc_GRK |
| cd14032 | 316-557 | STKc_WNK2_like |
| cd14207 | 303-564 | PTKc_VEGFR1 |
| cd05579 | 316-546 | STKc_MAST_like |
| cd06648 | 306-509 | STKc_PAK_II |
| cd14043 | 322-563 | PK_GC-2D |
| cd07829 | 313-520 | STKc_CDK_like |
| cd05572 | 316-548 | STKc_cGK |
| cd06652 | 307-546 | STKc_MEKK2 |
| cd07851 | 303-537 | STKc_p38 |
| cd14031 | 316-557 | STKc_WNK3 |
| cd14087 | 316-509 | STKc_PSKH1 |
| cd14070 | 314-546 | STKc_HUNK |
| cd05097 | 304-563 | PTKc_DDR_like |
| cd14071 | 314-509 | STKc_SIK |
| cd05087 | 313-522 | PTKc_Aatyk1 |
| cd14193 | 302-509 | STKc_MLCK4 |
| cd14068 | 316-563 | STKc_LRRK2 |
| cd14075 | 316-509 | STKc_NIM1 |
| cd05595 | 314-509 | STKc_PKB_beta |
| cd14049 | 308-503 | STKc_EIF2AK1_HRI |
| cd06659 | 315-576 | STKc_PAK6 |
| cd14030 | 280-557 | STKc_WNK1 |
| cd06639 | 306-564 | STKc_myosinIIIB_N |
| cd07877 | 303-536 | STKc_p38alpha |
| cd14079 | 311-512 | STKc_AMPK_alpha |
| cd14048 | 308-558 | STKc_EIF2AK3_PERK |
| cd14077 | 311-509 | STKc_Kin1_2 |
| cd14012 | 328-564 | PK_eIF2AK_GCN2_rpt1 |
| cd08221 | 353-564 | STKc_Nek9 |
| cd05570 | 314-521 | STKc_PKC |
| cd06621 | 309-509 | PKc_Pek1_like |
| cd14137 | 311-565 | STKc_GSK3 |
| cd14219 | 309-502 | STKc_BMPR1b |
| cd05603 | 314-509 | STKc_SGK2 |
| cd14183 | 314-520 | STKc_DCKL1 |
| cd05583 | 316-517 | STKc_MSK_N |
| cd14184 | 314-565 | STKc_DCKL2 |
| cd14188 | 339-564 | STKc_PLK2 |
| cd08219 | 311-565 | STKc_Nek3 |
| cd05593 | 313-509 | STKc_PKB_gamma |
| cd05037 | 317-564 | PTK_Jak_rpt1 |
| cd05096 | 333-567 | PTKc_DDR1 |
| cd07834 | 311-583 | STKc_MAPK |
| cd14114 | 312-510 | STKc_Twitchin_like |
| cd05602 | 307-509 | STKc_SGK1 |
| cd14076 | 312-509 | STKc_Kin4 |
| cd06617 | 309-565 | PKc_MKK3_6 |
| cd07841 | 313-503 | STKc_CDK7 |
| cd05630 | 316-511 | STKc_GRK6 |
| cd14665 | 311-563 | STKc_SnRK2-3 |
| cd05042 | 314-522 | PTKc_Aatyk |
| cd14086 | 308-509 | STKc_CaMKII |
| cd07833 | 313-505 | STKc_CDKL |
| cd07838 | 311-502 | STKc_CDK4_6_like |
| cd05095 | 333-568 | PTKc_DDR2 |
| cd14186 | 311-509 | STKc_PLK4 |
| cd05613 | 311-510 | STKc_MSK1_N |
| cd05604 | 313-516 | STKc_SGK3 |
| cd14004 | 313-565 | STKc_PASK |
| cd14210 | 311-505 | PKc_DYRK |
| cd14045 | 327-563 | PK_GC_unk |
| cd14191 | 314-509 | STKc_MLCK1 |
| cd05616 | 309-509 | STKc_cPKC_beta |
| cd14163 | 311-546 | STKc_TSSK3-like |
| cd14111 | 306-509 | STKc_SPEG_rpt2 |
| cd05094 | 309-575 | PTKc_TrkC |
| cd14190 | 316-509 | STKc_MLCK2 |
| cd14161 | 311-509 | STKc_NUAK2 |
| cd07878 | 303-536 | STKc_p38beta |
| cd14116 | 316-509 | STKc_Aurora-A |
| cd14173 | 332-509 | STKc_Mnk2 |
| cd14110 | 346-516 | STKc_obscurin_rpt2 |
| cd14078 | 311-509 | STKc_MELK |
| cd14090 | 316-510 | STKc_Mnk |
| cd13988 | 316-509 | STKc_TBK1 |
| cd05093 | 312-576 | PTKc_TrkB |
| cd14082 | 303-509 | STKc_PKD |
| cd06651 | 314-510 | STKc_MEKK3 |
| cd14166 | 316-509 | STKc_CaMKI_gamma |
| cd14181 | 301-549 | STKc_PhKG2 |
| cd14160 | 316-568 | PK_IRAK3 |
| cd13990 | 311-558 | STKc_TLK |
| cd06638 | 307-564 | STKc_myosinIIIA_N |
| cd07871 | 313-505 | STKc_PCTAIRE3 |
| cd14182 | 301-521 | STKc_PhKG1 |
| cd05594 | 304-509 | STKc_PKB_alpha |
| cd13994 | 316-511 | STKc_HAL4_like |
| cd13995 | 316-564 | STKc_MAP3K8 |
| cd06658 | 315-509 | STKc_PAK5 |
| cd05619 | 312-509 | STKc_nPKC_theta |
| cd14165 | 316-509 | STKc_TSSK1_2-like |
| cd14185 | 314-546 | STKc_DCKL3 |
| cd05571 | 314-511 | STKc_PKB |
| cd07854 | 313-505 | STKc_MAPK4_6 |
| cd14141 | 319-502 | STKc_ACVR2a |
| cd14131 | 311-565 | PKc_Mps1 |
| cd14001 | 309-513 | PKc_TOPK |
| cd05620 | 314-509 | STKc_nPKC_delta |
| cd14174 | 332-546 | STKc_Mnk1 |
| cd14094 | 311-546 | STKc_CASK |
| cd05575 | 314-557 | STKc_SGK |
| cd05614 | 311-516 | STKc_MSK2_N |
| cd07870 | 313-506 | STKc_PFTAIRE2 |
| cd14140 | 319-504 | STKc_ACVR2b |
| cd14107 | 314-558 | STKc_obscurin_rpt1 |
| cd14209 | 312-521 | STKc_PKA |
| cd14017 | 303-546 | STKc_TTBK |
| cd08228 | 308-509 | STKc_Nek6 |
| cd14050 | 311-504 | PKc_Myt1 |
| cd14092 | 399-524 | STKc_MSK_C |
| cd14167 | 316-509 | STKc_CaMKI_alpha |
| cd05612 | 308-509 | STKc_PRKX_like |
| cd14074 | 312-546 | STKc_SNRK |
| cd14106 | 314-509 | STKc_DRAK |
| cd14088 | 349-509 | STKc_CaMK_like |
| cd14662 | 311-563 | STKc_SnRK2 |
| cd14083 | 314-509 | STKc_CaMKI |
| cd05615 | 308-509 | STKc_cPKC_alpha |
| cd05607 | 354-509 | STKc_GRK7 |
| cd05086 | 313-516 | PTKc_Aatyk2 |
| cd06618 | 417-565 | PKc_MKK7 |
| cd07873 | 313-505 | STKc_PCTAIRE1 |
| cd06620 | 285-564 | PKc_Byr1_like |
| cd14038 | 315-509 | STKc_IKK_beta |
| cd05592 | 314-520 | STKc_nPKC_theta_like |
| cd07836 | 311-587 | STKc_Pho85 |
| pfam00130 | 99-144 | C1_1 |
| cd05587 | 313-509 | STKc_cPKC |
| cd14132 | 302-451 | STKc_CK2_alpha |
| cd07880 | 303-505 | STKc_p38gamma |
| cd14067 | 316-559 | STKc_LRRK1 |
| cd14117 | 316-565 | STKc_Aurora-B_like |
| cd14133 | 311-558 | PKc_DYRK_like |
| cd06657 | 315-509 | STKc_PAK4 |
| cd14052 | 311-501 | PTKc_Wee1_fungi |
| cd13987 | 409-554 | STKc_SBK1 |
| cd14169 | 308-509 | STKc_CaMKI_beta |
| cd05608 | 316-509 | STKc_GRK1 |
| cd07856 | 313-587 | STKc_Sty1_Hog1 |
| cd05631 | 316-509 | STKc_GRK4 |
| cd07832 | 311-588 | STKc_CCRK |
| cd06622 | 308-564 | PKc_PBS2_like |
| cd07845 | 306-523 | STKc_CDK10 |
| cd07847 | 313-505 | STKc_CDKL1_4 |
| cd05605 | 353-509 | STKc_GRK4_like |
| cd14104 | 316-509 | STKc_Titin |
| cd05574 | 311-546 | STKc_phototropin_like |
| cd14037 | 310-571 | STKc_NAK_like |
| cd07831 | 311-504 | STKc_MOK |
| cd07844 | 313-505 | STKc_PCTAIRE_like |
| cd14105 | 311-509 | STKc_DAPK |
| cd14005 | 311-565 | STKc_PIM |
| cd05632 | 316-509 | STKc_GRK5 |
| cd14044 | 333-567 | PK_GC-C |
| cd14196 | 316-509 | STKc_DAPK2 |
| cd07872 | 313-505 | STKc_PCTAIRE2 |
| cd14198 | 314-558 | STKc_DRAK2 |
| cd07866 | 311-505 | STKc_BUR1 |
| cd14168 | 316-509 | STKc_CaMKI_delta |
| cd07843 | 309-451 | STKc_CDC2L1 |
| cd05589 | 316-546 | STKc_PKN |
| cd14195 | 314-509 | STKc_DAPK3 |
| cd07849 | 304-574 | STKc_ERK1_2_like |
| cd07869 | 313-522 | STKc_PFTAIRE1 |
| cd05611 | 313-518 | STKc_Rim15_like |
| cd14039 | 316-511 | STKc_IKK_alpha |
| cd07855 | 308-451 | STKc_ERK5 |
| cd07863 | 316-502 | STKc_CDK4 |
| cd05590 | 316-509 | STKc_nPKC_eta |
| cd14157 | 316-505 | STKc_IRAK2 |
| cd14016 | 311-452 | STKc_CK1 |
| cd05618 | 309-516 | STKc_aPKC_iota |
| cd07879 | 303-505 | STKc_p38delta |
| cd14172 | 380-546 | STKc_MAPKAPK3 |
| smart00109 | 99-144 | C1 |
| cd05573 | 308-510 | STKc_ROCK_NDR_like |
| cd05584 | 313-530 | STKc_p70S6K |
| cd06619 | 309-512 | PKc_MKK5 |
| cd14108 | 314-526 | STKc_SPEG_rpt1 |
| cd14036 | 316-570 | STKc_GAK |
| cd07865 | 308-506 | STKc_CDK9 |
| cd14118 | 411-510 | STKc_CAMKK |
| cd14091 | 309-564 | STKc_RSK_C |
| cd08229 | 314-509 | STKc_Nek7 |
| cd07846 | 311-505 | STKc_CDKL2_3 |
| cd07875 | 297-564 | STKc_JNK1 |
| cd14051 | 313-508 | PTKc_Wee1 |
| cd14194 | 316-509 | STKc_DAPK1 |
| cd14112 | 306-520 | STKc_Unc-89_rpt2 |
| cd14180 | 400-509 | STKc_MSK2_C |
| cd05617 | 309-512 | STKc_aPKC_zeta |
| cd14089 | 372-513 | STKc_MAPKAPK |
| cd14197 | 411-553 | STKc_DRAK1 |
| cd14179 | 409-517 | STKc_MSK1_C |
| cd05610 | 309-456 | STKc_MASTL |
| cd14200 | 354-509 | STKc_CaMKK1 |
| cd14199 | 342-563 | STKc_CaMKK2 |
| cd14176 | 311-528 | STKc_RSK2_C |
| cd14177 | 308-564 | STKc_RSK4_C |
| cd13977 | 412-558 | STKc_PDIK1L |
| cd07853 | 309-547 | STKc_NLK |
| cd14085 | 314-546 | STKc_CaMKIV |
| cd14170 | 372-546 | STKc_MAPKAPK2 |
| cd07839 | 313-508 | STKc_CDK5 |
| cd07858 | 305-574 | STKc_TEY_MAPK |
| cd13975 | 405-559 | PKc_Dusty |
| cd07842 | 316-451 | STKc_CDK8_like |
| cd05588 | 416-516 | STKc_aPKC |
| cd05585 | 316-509 | STKc_YPK1_like |
| cd05609 | 368-530 | STKc_MAST |
| cd07874 | 311-564 | STKc_JNK3 |
| cd07857 | 311-505 | STKc_MPK1 |
| cd14223 | 316-517 | STKc_GRK2 |
| cd05606 | 316-517 | STKc_beta_ARK |
| cd05591 | 314-509 | STKc_nPKC_epsilon |
| cd07862 | 316-502 | STKc_CDK6 |
| cd07864 | 309-504 | STKc_CDK12 |
| cd07859 | 311-593 | STKc_TDY_MAPK |
| cd13968 | 316-449 | PKc_like |
| cd14178 | 417-525 | STKc_RSK3_C |
| cd14040 | 312-586 | STKc_TLK1 |
| cd05077 | 337-567 | PTK_Jak1_rpt1 |
| cd08226 | 333-543 | PK_STRAD_beta |
| cd05596 | 417-549 | STKc_ROCK |
| cd05633 | 308-517 | STKc_GRK3 |
| cd07876 | 311-523 | STKc_JNK2 |
| cd14134 | 313-507 | PKc_CLK |
| cd06650 | 304-508 | PKc_MEK1 |
| cd14113 | 308-509 | STKc_Trio_C |
| cd07852 | 400-505 | STKc_MAPK15-like |
| cd14041 | 312-585 | STKc_TLK2 |
| cd14175 | 316-576 | STKc_RSK1_C |
| cd14138 | 308-494 | PTKc_Wee1a |
| cd07850 | 311-523 | STKc_JNK |
| cd05600 | 308-510 | STKc_Sid2p_like |
| cd05586 | 316-509 | STKc_Sck1_like |
| cd05076 | 337-564 | PTK_Tyk2_rpt1 |
| cd05622 | 286-548 | STKc_ROCK1 |
| cd14018 | 412-574 | STKc_PINK1 |
| cd05078 | 310-564 | PTK_Jak2_rpt1 |
| cd14100 | 316-564 | STKc_PIM1 |
| cd14011 | 317-558 | PK_SCY1_like |
| cd14136 | 311-505 | STKc_SRPK |
| cd14102 | 316-565 | STKc_PIM3 |
| cd05621 | 304-548 | STKc_ROCK2 |
| cd14139 | 313-513 | PTKc_Wee1b |
| pfam00069 | 311-564 | Pkinase |
| pfam07714 | 310-567 | Pkinase_Tyr |
| smart00219 | 310-564 | TyrKc |
| smart00221 | 310-564 | STYKc |
| smart00220 | 311-565 | S_TKc |
| COG0515 | 309-586 | SPS1 |
| PLN00034 | 254-509 | PLN00034 |
| PHA03209 | 311-573 | PHA03209 |
| PTZ00266 | 308-565 | PTZ00266 |
| PTZ00263 | 308-509 | PTZ00263 |
| PTZ00267 | 412-571 | PTZ00267 |
| PHA03212 | 345-505 | PHA03212 |
| PTZ00024 | 310-595 | PTZ00024 |
| PHA03211 | 306-507 | PHA03211 |
| TIGR03903 | 333-505 | TOMM_kin_cyc |
| PRK13184 | 415-548 | pknD |
| PTZ00283 | 419-558 | PTZ00283 |
| PHA03207 | 311-502 | PHA03207 |
| PHA03390 | 398-509 | pk1 |
| PHA03210 | 211-507 | PHA03210 |
| PHA02988 | 351-569 | PHA02988 |
Ontology Information
| HPRD ID | 1112 |
|---|---|
| Molecular Class | Serine/threonine kinase |
| Molecular Function | Extracellular matrix structural constituent (GO:0005201) |
| Biological Process | Transport (GO:0006810) |
Drug Information
| Uniprot ID | DrugBank ID | Name | Type |
|---|---|---|---|
| P10398 | DB00171 | Adenosine triphosphate | SmallMoleculeDrug |