Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| BTLA | 151888 | B and T lymphocyte associated | 3 | BTLA1, CD272 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25604582 | 2015 | Cell line : - Source : Heilongjiang Province of China. Sample Type : Hospital-based case-control study No. of Sample : 601 cases CRC and 627 control Stage : - | - | Polymorhpism | - | Data indicate potential associations between BTLA and PD-1 polymorphisms and CRC susceptibility. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | CD molecules, "Immunoglobulin superfamily / Immunoglobulin-like domain containing" |
| Description | This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011] | Chromosome | 3 |
| Location | 3q13.2 |
| Start | 112182813 |
| End | 112218438 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 35626 |
| OMIM ID | 607925 |
| HGNC ID | HGNC:21087 |
| Unigene ID | Hs.445162 |
| Ensembl ID | ENSG00000186265 |
| PharmGKB ID | PA134968341 |
Protein Information
| Protein ID | NP_001078826.1 |
|---|---|
| Protein Name | B and T lymphocyte associated |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 289 |
| Uniprot ID | P07437 |
| Ensembl Protein ID | ENSP00000339001 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 5777 | PTPN6 | 1475 | NP_536859.1 | in vivo | 12796776 |
| 5781 | PTPN11 | 1470 | NP_002825.3 | in vivo | 12796776 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00096 | 55-117 | Ig |
| cl11960 | 55-117 | Ig superfamily |
| pfam07686 | 80-133 | V-set |
| pfam00047 | 51-117 | ig |
| smart00410 | 43-133 | IG_like |
| smart00409 | 43-133 | IG |
Ontology Information
| HPRD ID | 1852 |
|---|---|
| Molecular Class | Cell surface receptor |
| Molecular Function | Structural constituent of cytoskeleton (GO:0005200) |
| Biological Process | Cell growth and/or maintenance (GO:0008151) |
Drug Information
No matching records could be found.