CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
CAD	790	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	2	-

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
25450519	2014	Cell line : - Source : - Sample Type : CRC tumor and normal tissues No. of Sample : 79 GCs and 124 CRC Stage : -	SSCP and direct sequencing analyses	Mutation	-	-

Gene Details

NC_000002.11 (27440258..27466660)
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Gene Type	protein coding
Gene Family	-
Description	The de novo synthesis of pyrimidine nucleotides is required for mammalian cells to proliferate. This gene encodes a trifunctional protein which is associated with the enzymatic activities of the first 3 enzymes in the 6-step pathway of pyrimidine biosynthesis: carbamoylphosphate synthetase (CPS II), aspartate transcarbamoylase, and dihydroorotase. This protein is regulated by the mitogen-activated protein kinase (MAPK) cascade, which indicates a direct link between activation of the MAPK cascade and de novo biosynthesis of pyrimidine nucleotides. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]
Chromosome	2
Location	2p22-p21
Start	27440258
End	27466660
Strand	+
Gene Sequence	>gi\|568815596:27217390-27243792 Homo sapiens chromosome 2, GRCh38.p2 Primary Assembly GCGCGCCCGAGGCTCCTACGCTGCCGCGCCCGGCTTCTCTCCAGCGCCCCGCGCCGTTAGCCACGTGGAC CGACTCCGGCGCGCCGTCCTCACGTGGTTCCAGTGGAGTTTGCAGTCCTTCCCGCTTCTCCGTACTCGCC CCCGCCTCTGAGCTCCCTTCCCATGGCGGCCCTAGTGTTGGAGGACGGGTCGGTCCTGCGGGGCCAGCCC TTTGGGGCCGCCGTGTCGACTGCCGGGGAAGTGGGTAAGCAAGCCCGGTTAGGCTGCAGACCTTATCCCA CTCTGTGATGCGCCTCTCCTCCCAACCTTCCCCGTCCAGACCCCGCCATTTTCCCGCCAGCGTACCCCCT TCCCCCATTCGGTGCCCATGGGCCCCAGCGCCATAAACCCCTCGCGACCAAGGCAGCCTCCACTGGGGCG TGCTCATCGCGCGGGGAGTGTTCCGAAGGGTGCCCTACCGGAGCCCAGCCCTGCTTCTTTCTTGCAGTGT TTCAAACCGGCATGGTCGGCTACCCCGAGGCCCTCACTGATCCCTCCTACAAGGCACAGATCTTAGTGCT CACCTATCCTCTGATCGGCAACTATGGCATCCCCCCAGATGAAATGGATGAGTTCGGTCTCTGCAAGGTA GCCACACCCAGTGCTTTCTCTACATTCCTTTTCAAGTCAGTAATTGTTAACTATTAGTGAAGTAGGAGAC GTTGACACCCTGCTGGGCATCCTGCAGAAAACATACCCACTGAAGTAGTAAAGTCAAGGACTAAGATCAC TAGTAACTGTAGTTAGGGGTTGTTAAGTGCCTTGGGAGGCACAGAGTGTTGGAGGCCTCAGGAAAAAGCT ACCGCCTTTGTTAAGGGCATCAAGGCTCCAGGTATAGCTGAAAGCATTCTGTATGTAGTGAAGGCATGGA TCAAGGAAAAGTAAAAGAGGTGTAAGGGAACAGCCTTGTCCAACTTGTTAGGCATGCAGAAGTCAGGAGA AAAAAGCCTGCAGATAAGTTAAATCCGGTGGGCATGGAGGGACCTGAAGCCAAAGCAGAGTCAGCTTAGT TTGGTAAAGGATCCATTGAAGGTTTTTTTTTAGCAGCAGAGTCAGATGGGAGCAGTGCTTTTTAGGACTA CATAAATTAGTGGAAAGAGACTGGAAACTAGGGTCACATACTTCTCTGTGACAGTGAGTGCCAGTTTACC TACAAAACCAGTGACATTATCTTCTAGACCTACTGACATGGCCTCGTCTGATTCTCTGCTTTTCAGTTGT GTTCTTACCTCTAGGTGAGAAAACTGAGTTTCTTCCTACAGTGAGGTTTCCCCTATTCCTTCACCTCTGA AATTTGGAAACTAAGTTGCCCTCTGACAGTTCAAGCATTAAAAAAAACCCAACATATAGTAATTAAGGTA ATAGAGGAAGTCAATCTGGCCTAGAGTAGTATCTCTCAAAATTTGTTTGGCCTCACTGCAGGTGTAAGCC TTTAATTCTTAATTTGCCTTCCCAGCCACCCTGACGCTGGGGAGAGTGAGCTCCGGATAAAGGACGTACA TGTTGTTCTTCCTGGAAAAGAATTTCTAGGTTCATCACAAACCTACAAATACACTGCATTCTAGTTGATA GTGAATTCTTGTGAATTTGGTTAACCTTTGTCAGTCATCACCTTTGTCAACTCTAGACACACTGACTAAA TTGAGTTTATAAAACTACAAAATTGAGGCCTGATTAGGATCAGGGTGGGAAAGGCCTCTTGGAGCCACTC GCACATATAAATGGATTACTCCACCTGGCCAGGGAGGGTTCTGCCAAACTATCCTTCAGATCCCTGGACA GTCTCAGAATGCAGGTTCCTTAAACTGTTCATCACCCAGCTGAATGCAGTTTAAATATGCTGATCCCTCC CACATAAACTTTCTGTTTCTATGTAGCTATTAAACGCTTATCTATTGAGTAACAAGTTTATGGTTTTTGT TTTTTTTTTGGGGACAAGGTCTCACTTTGTCACCCAGGCTGGAGTGCAGTGGCATAATCATGGCTCACTT GCAGCCTCTGCCACCTGAGCTCAAGTAGTCCTCCCACCTCAACCCCCCAAGTAGCTGGGACTACAGGCAC CTGCCGCCATGCCTGGCTACTTTTTTTGTATTTTTTGTAGAGACCGGGTATTGTCACATTGCCCAGGCTT GTATGTTATCTTTTTTTATTTAATTTTTTTTTATTTTTATTTTGCTTTGAGGTAGAGTTTCTTTCTTGTT GCTCAGGTTGGAGTGCAATGGGCAACCTTGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCTATTCTC CCACCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGGGCTACCATTCCCAGCTAATTTTGTATTTTTA GTAGAGACAGGGTTTCTCCATGTTGGTCAGGCTGGTTTTGAACTCCCGATCACAGGTGATCTGCCCACCT CGGCCTCCCAAAGCGCTGGGATTACAGGCGTGAGCCACCGCGCCTGGCCTTTTCTTTTTTAAATAATCCC AAATGAAGTTTGGGAGGCATGCTTAGTATTGTGCCCTGAACCTTTGTTTTTTATTTGGTAATGGGGTATT TTGTACCTCCCTATCTTACTCAGTTTTTAATCACACTCTATAATTAATATTTATATGGGTGTTACCTTGT TTTCTAGCTCCCTAAGTCAGAAATAAACATCATGAAGACAGGAACCTCATCTTTTTTTGCTCATTGCTCT TTTCTCAGCATCTTTTGCAATGCCTGCACCTCAATAAATGTCTGACTGACACCATGTGCCTTGCTCTTGA GTTCTCTGTTTCGTGACAAAGACACAAATACATATTCATCATATGACGTAAATAGCAAGAGAGGAAATAA AGTATTAAAACAGCTCTAAGATGGAGGCACAAGCTGTATTGGGTGAGTGGGAGGGGCTTCACAGAGAAAG GATTTGTGATTTCAGTTTTAGATAAAGGAAGAAAGAGGCGGGGCGCGGTAGCTCATGACTTGTAATCCCA GCACTTTGGAAGGCTGAGGTGGGGGGATCGCTTGAGCCCAGGAAGTTTGAGAGCAGCCTGGCAACATGGT GAGACGCTGTCACTACAAAAAATTCAAAAAATTAGCCAGGTGTGATGATCCACACCTGTGGTCCCAACTA CTCAGGAGTCTGAGGTGGGAGAATCACTTGAGCCCAGGAGATTGAGGCTGTAGTGAACCGTGTATTTGTG CCACTGTACTCTGCACTCCAGCCTGGATAACAGCAAGACCCTGTCTCAAAAAAAAAAAAAAGGAATGGCT AGGTGCGATGGCTCACTCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCAGATCACAAGGTCAGGA GATCTGAGACCATCCTGGCTAACATGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGTG TGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTAAAGCAAGAGAATTGCTTGAATCCGGGAGGC AGAGGTTGCAGTGAGCTTAGATGTCGCCACTGCATTGCAGCCTGGGTGACAGAGTGAGACTCTGTCTCAA AAAAAATAAATAATAAATAAATAAAAAGGAAAATGTCATTTTCAGTGATCATCGGGGCACCCTGGGCCTG TGGGTTGTGTTTCGTATAGGAGAGAGCGTTGTTGGTAAATGGAAATACCTATGCAAAAGCACCAAAAGTT TGGTATATTGAAGGCCATTCAATGTGGCTGAATATAGGGTCTGTGGCCACACAATCGGGAAAATGCTGCA AAGAAATAACTTGGCCTGAGGCTTCTCACAATCTCTTTCCATCTACAGTGGTTTGAATCCTCGGGCATCC ACGTAGCAGCACTGGTAGTGGGAGAGTGCTGTCCTACTCCCAGCCACTGGAGTGCCACCCGCACCCTGCA TGAGTGGCTGCAGCAGCATGGCATCCCTGGCTTGCAAGGTATGGTGGCAAGCAGGGGCATATTTGGGCAG AGCACAGCATGCCTGGATGGAAAGAATCAAGGTTTCTGTAATCTGCTGGGACCTGACTCTAAGATTGTGA TAGTTGGAAGGTTTAGATTGGAGTTGGGCTGGGAGAAAGAATTGAACTATCACTCAGAAAGAAAATTTCC AACACAGGAAGGAACTCCCACCTTCCATAATCATCAGCTTAGGGCTAATCTTATTTCATCACCACCACTG GATTATTTTGATGCAAATCTCAGACATCATATCATTTCATCTACAAATAGTTCAATATCTATGCAAAAGG AATCTTTAAAAAACATGATCATAATAACGTCATACACTAAAAAAATTAATAATTCCCTAATACAAGTGTC CAGGCAATGTTTAAAATTTCCCAATTTTTTTTTTTTTTTTTTTTTTTTTTTCTGTTCATTTGAATCTTGC TCTAAACAGGGTTCACACATTGCATTTGGTTGATAAGTCTCTTAATCTGTGGACCTTGTAACCTATTTGA AAACAGGTCATTTTTCCTGTATCTAGTATCCCATAGTCTGCACTTACTTGGTTACACTCCTGTAGTGTTA CTTAGCGTATTCTTTTTTTCCCTTTATATTATTTTCTATAAATGGATAGATTTAGAGTTGTTCAATTCAG ATGTGATATTTTTGGCAGGAATACTTCATGGTAGTATACTTCTGTCACAATGGCCCAGGATTTTGATGCA CATAGAACAGCTGTGTGTGACTGGGGCTCTGGAATGGAAGTGCTTCTGGAAGTCTAACCTCACAGATGAC TGAGTTGTAGGAATGTGATCCCTAAGACTGTGCTATTTTGACAGGAGTAGACACTCGGGAGCTGACCAAG AAGTTGCGGGAACAGGGGTCTCTGCTGGGGAAGCTGGTCCAGAATGGAACAGAACCTTCATCCCTGCCAT TCTTGGACCCCAATGCCCGCCCCCTGGTACCAGAGGTCTCCATTAAGGTACAGAGGTAGAGTGGGAGAGT GTTGCAAGCTCTAGCACAGTAGTTATATTCTGCCCACAATTGGGGGGTGAACACAGGAGAGAATCAAAGG AGGCTTTGAAGGTAGGAGTTGGTGCAGGCATATCTTATACCCACTGAGCACAGCTGCCAACTGTTGCCCT TTATTCGTCTATTTCTCAGACTCCACGGGTATTCAATACAGGGGGTGCCCCTCGGATCCTTGCTTTGGAC TGTGGCCTCAAGTATAATCAGATCCGATGCCTCTGCCAGCGTGGGGCTGAGGTCACTGTGGTACCCTGGG ACCATGCACTAGACAGCCAAGGTGAGTAGCTGGGGCCTGTTCAGGGCCTCAGACAAGCAGCTTGGGTGGA AGATCTATCCCTTGGTCCAATTGCTAAAAGTCAGTAGGAGTTGCAGTGAAGAAGATAGACATTGGGACTT AACACTCTCATGGGCTGGGGGGGCTGCAGGTGTGTCTCCTGTAATTGAAATACTGATTTTGATGTCATCT TTTCTGCCCACTCCAGAGTATGAGGGTCTCTTCTTAAGTAATGGGCCTGGTGACCCTGCCTCCTATCCCA GTGTCGTATCCACACTGAGCCGTGTTTTATCTGAGCCTAATCCCCGACCTGTCTTTGGGATCTGCCTGGG ACACCAGCTATTGGCCTTAGCCATTGGGGCCAAGACTTACAAGATGAGGTGGGACTTGTGGGGAGCAGAA GGGGCCCATACTTGTGGCATGAGGGGTGGGGTGTCTCAGGAATGAGAAGAGAGTTGGTGTTTATTCGTGT TGAAATAGGAGCGGGGGGGTTGCAGGTGAGGTGGCTCCCACCTGTAATCCCAGCACTTTGGGAGGCCAAG GTGGGCGGATCACTGGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACTCTGTCTCTACTA AAAATACAAAAGTTGGCCAGCCATGGTGGCGTGCGCCTGTAATCCCAGCTACTCCAGAGGCTGAGGCAGG AGAATCGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGCGGAGATCGTGCCATTGCCCTCCAGCCCGGGA AACAGAGGGAGACTCCGTCTCAAAAAAAAAAAAAAAACAAAAAGGAAACAGGAGTGAGGCTACTGAGAAC AGGAGATCGGTGAGAGCTGGGGTAGGTTCAGTAGTGAAGAGAGGGTGAGCAGGGCCTGTGACTCGGCATG CTTCTACCTCCAGATATGGGAACCGAGGCCATAACCAGCCCTGCTTGTTGGTGGGCTCTGGGCGCTGCTT TCTGACATCCCAGAACCATGGGTTTGCTGTGGAGACAGACTCACTGCCAGCAGACTGGGCTCCTCTCTTC ACCAACGCCAATGATGGTTCCAATGAAGGCATTGTGCACAACAGCTTGCCTTTCTTCAGGTGAGCCTGGT TGACTGGGTCTGTGAAAATTTGAAGCCCTGTGGGCCTTGATGATGGAAAAGTAAAGCACGGCAGTGGATC CGAGTCCCCTGTCCCACTACCCACCTCGAGGCTGCCAGTGTCATGCCAGGGACCATGATGGTTTTCATGA TGCAATCTCTTCAATAGTGTCCAGTTTCACCCAGAGCACCAAGCTGGCCCTTCAGATATGGAACTGCTTT TCGATATCTTTCTGGAAACTGTGAAAGAGGCCACAGCTGGGAACCCTGGGGGCCAGACAGGTAAGATCCT GAGTAGAACTGGGTTGTGGACCTAAGAACAGGGTTGGCTCCAGGATGGGCATAAGGTGGACATGCCCTGG GCAACTCCTAGATGTCTAGGAGGTTAAGGGTATTGGGGATGGGTGGCAACCAACCCAAGATACCGTTTAA GCTTCTGTTGAAAGGAACTCCAGGGTCCTGGGTTCTGGTCCTCCCTCTGCTCCTCCTGAGGTGCATAATT TGCTCTGGACTCTTCTGAAAGCGAGGGAGCTAATCCAGTTGACCTCTTGGGTCCAGCTCAGCTCTAACAT TCTACGACCTTCTTTGCTTCCACAGTTAGAGAGCGGCTGACTGAGCGCCTCTGTCCCCCTGGGATTCCCA CTCCCGGCTCTGGACTTCCACCACCACGAAAGGTTCTGATCCTGGGCTCAGGGGGCCTCTCCATTGGCCA AGCTGGAGAATTTGACTACTCGGGCTCTCAGGTGAGGCATGTTCCTCCCCACCCTTCTGGGCGTGTGACC CTCAAGAATGGAAAGGGTCTTAAGGAGAAGGGCTAAGGTTGCAGGGAGGAAATGAACCAGATTTGGGGAA TGTAGAGAAAGATGTAGTAAGAAATAGAAGTCAATTATTAGGGGCCAAGAGTACAGGGAGGGAAAGAAGA GGAGAATGCTACTCTAAGGCTGTTTGCAATTTTGCTTCTTCAGCAGAGGCTGAGATGCCATTCTTGTCCT TTTAGGCAATTAAGGCCCTGAAGGAGGAAAACATCCAGACGTTGCTGATCAACCCCAATATTGCCACAGT GCAGACCTCCCAGGGGCTGGCCGACAAGGTCTATTTTCTTCCCATAACACCTCATTATGTAACCCAGGTA TGACTGGGGCAAGGCTGGAATGAAAAGAGGACTGGGCAGGGGGGCCCAGTGGTCACTGTGGGTTATTAAA CTTTGATTGCCTCTCTACCCACAAGGTTCTGATGCCTGTAACTCCCCTCTCCATCCTCAGGTGATACGTA ATGAACGCCCCGATGGTGTGTTACTGACTTTTGGGGGCCAGACTGCTCTGAACTGTGGTGTGGAGCTGAC CAAGGCCGGGGTGCTGGCTCGGTATGGGGTCCGGGTCCTGGGCACACCAGTGGAGACCATTGAGCTGACC GAGGATCGACGGGCCTTTGCTGCCAGAATGGCAGAGATCGGAGAGCATGTGGCCCCGAGCGAGGCAGCAA ATTCTCTTGAACAGGTTGGAGGGGTGTTTGGGTAAAGGAAGAATGGTGGTGTTTTTTTTGGTAGTGTTAT TTTCTTTTTTTTTTTTTTTTTTTTGAGACGGAGTTTCGCTCTTGTTGCGCAGGCTGGAGTACAGTGGCGT GATCTCGGCTCATCATAACCTCCACCTCCCAGATTCAAGCGACTCTCCTGCCTCAGCTTCCTGAGTAGCT GGGATTACTGGCATGCGCCACCATGCCCAGCTAATTTTGTATTTTTAGTAGAGACGGGGTTTCTCCATGT TGGTCAGGCTGATCTCGAACTCCTGACCTCAGGTGATCCACCCCCCCGACCCTCGGCCTCCCAAATTGCT GGGGTTACAGGCGTGAGCCACTATGCCCAGCCATGTTATTTTCTTTATATCTTTTTTTATGTGGGACAGG CACACCTTGGACAGTAGGAAATAACCTGTTTGTTCATCTCTTCCACTCATTGCAGGCCCAGGCAGCCGCT GAACGGCTGGGGTACCCTGTGCTAGTGCGTGCAGCCTTTGCCCTGGGTGGCCTGGGCTCTGGCTTTGCCT CTAACAGGGAGGAGCTCTCTGCTCTCGTGGCCCCAGCTTTTGCCCATACCAGCCAAGTGCTAGTAGACAA GTCTCTGAAGGGATGGAAGGAGATTGAGTACGAGGTGGTGAGAGACGCCTATGGCAACTGTGTCACGGTG AGTGAATGGGGGAAGGGTGGGCGTCGTGTCAGGCAGGATGAGCTTTTGGAAGAGCAGAGGCCCAGGCCAA GGTCTTTGAGAGTTGTATGTCCCTCAGACCCAGGTTAGGTGCAGCCCCAGAGGTAACAGGACCCTGGGGT GCAGCCTTCTGCCTCTCCTGACTCTGCTTGGCAGTGACCTCCATGGCACCCCCCTTCACAGGTGTGTAAC ATGGAGAACTTGGACCCACTGGGCATCCACACTGGTGAGTCCATAGTGGTGGCCCCTAGCCAGACACTGA ATGACAGGGAGTATCAGCTCCTGAGGCAGACAGCTATCAAGGTGACCCAGCACCTGGGAATTGTTGGGGA GTGCAATGTGCAGTATGCCTTGAACCCTGAGTCTGAGCAGGTAAGCTCTAGGCCCTGGAACTGATAGTCT AGTTGTTACCCCCTCTTCTTGTATAATTTTTGGCCCTTGAGGTTGAGGTCTTTTGGGCTTACAGTCCCTG GAGTACAAGCTGGAATCTTCTTTACTAGGTTACTTTTCTCTCCTTTCTGAGACCTCTCCTAGACAGGGTC TTCTAGGCCAGTGACTTTATTCTCCTTCTTTGCAGTATTACATCATTGAAGTGAATGCCAGGCTCTCTCG CAGCTCTGCCCTGGCCAGTAAGGCCACAGGTTATCCACTGGCTTATGTGGCAGCCAAGCTAGCATTGGGC ATCCCTTTGCCTGAGCTCAGGTACGAGGATGAGGGAGATATCACAGTGGGGAAGTGGGTCGGGGGCTGAG GAAAATATTGATGGGACAGGGAATATGAAAAGGACATTGGCCTGGATTTGTGGGAATGGAAAGAGCTATC CGGAAGCTCACCCTTTATGCTTCCTTCACTGTCCTTCTGGCATCCCACCTGCTGGACCCCAGGAACTCTG TGACAGGGGGTACAGCAGCCTTTGAACCCAGCGTGGATTATTGTGTGGTGAAGATTCCTCGATGGGACCT TAGCAAGTTCCTGCGAGTCAGCACAAAGATTGGGAGCTGCATGAAGAGCGTTGGTGAGACTCATGCCCTG GGCACCCCCATGGGGCCCCACCATGACCAAGAATCTTAAATGTCAAGAGTTCCCTGGCATGGCCTTTTAC GTCCTATGGGAGCAGGTGCTTGAGACATTTCAAACTAAGATTATAGTCCTTGTCAGGAGTTGGGGAGGCA TCTGGAAATCTGTGTTGGAATACAGAATCTCTGGGATAGGTGCAAGCCATCAGACTATCTCATCTCATTT TTGCAGTATCTCCTCCTCTGGCACTTTGTGCTTTGGTCACTAAATGACCTTTTTTTTTAGTATGATGTTT ACATCAGAGCAGGGCATCATAAACCTTTTTGGTAACAAGGAAATTTATTAGTGAATGATGAATGGCCGTA ACGTTACCCAGCAGTGGCAGAGCATGTTAGAATTGAGTTAGTATGTTTCTTTGTGGTATCCCTTTAGTTG CCGAAGACCGTCCTCTAACACATTTCAACCAAAACAAAAATATACGTGTACCAGACACAGCGCCACCAGC CTGATGGATAAGAGCATTTTGTGGTGCTCCAGATTTCCATTTAGAGCAGTAGTGGCCTTTAAACAAGTAA GTCTAAGCTCAGATATTATTTCAGAATTTTTAGAAATTCTGCAAGACTGCCAATTTTTTCCTTCTGGAGA TGAATCTCTGTTATATGAAAATTAGAATAAACATGGGAATGAAGCCATAATTAAATTGTGGCAAAAAGAA GTGGATTGAAAATAGGCCAATGAAAGATTGGTTCCTAGATGAGACATTTAATTGTTTTACATCTGTTCAA GTATTCTTGGAATGTGGTCTTCTTTGGTAACTTTTTGTAACTTTTATTATACAAGTAAGAAACATGAATC ATGGAAAACGAGGAAAGATAGTTTAACCAAAGAACAGTAGTCACCTGTAATCTTGCCTTACAGAGATTGA TTAATTCGACCGTGTATCTGCGACTGCATAATTCAGCCGTGTATCTACGACTGCATACATTTCTAGGCAT ATGTGTATGCATGTATTAGGCTTCTCCTTTTTTAACAAATCTCAAAATAAAAAGTCTTACAACCACAGTT ACAAAGAAATTGAACAAAATCAGTCACACTACTGTTAACATCGTAGTGTTTTTAAAACTTTTTTAAAGAA ATGTAAATGTTAGGATTGTAAATAGAAAAATACACTTGGTAAGAAATACTTAAGCCCCTAGAGTAAATAG TCAGAGGAGATGAACAACACTTTACAGAAGAAGAAATCAATAAGCAAACCTAGAGAAAAGACGGTTCCTC TCATTAGTAAATAGAAATCTAGTTAAATGAGACTCTGTTTATGCCCACTTCTTAGAAGGTTGCTTAAACT TTGTATTATGAAGCACAGACTTCTATAAAGTTATTCGTACTCATCAAGGGCTATAAAATTTGTGTTACCT ATTGCCTCTACATATCTGGAAATTTATCCTAAGGAGATTATCCAAAACAGAAAACATCATATCCAGTCCA GGCACGGTGGTTGTAATTAATCCCAGCACTTTGGAAAGCTCAGGTGGGAGGATCGCTTGAGCCCACGAGT TCAAGGTTGCAGTGAGCTGTGATTGTACCACTGCATTCCAGTCTGGGTGCCAGGCTAAGACCCTGTCTTT TTTGTTTGTTTGTTTGTTTGAGACGGATTTTCATTCTTGTTGCCCAGGCTGGAGTGCAATGGTGTGATCT CGGCTCACCACAATCTCTGCCTCCTGGGTTCAAGTGATTCTCCTGTCTCAGCCTCCAGAGTAACTGGGAT TACAGGCATGTGCCATCACGCCTGGCTAATTTTGTATTTTAATAGAGACAGGGTTTCTCCCTGTTGGTCA GGCTGGTCTTGAACGCCCGTGCTCAGGTGATCCACCCACCTTTGGCCTCCCAAAGTGCTGGGATTACAGG CCACTGTGCCTGGCCGAGACCCTGTCTCTTTTTTCTTTTCTTTTTTTTTTTTCTTTTTTTTTTTTTTTGA GGCAGAGTCTTCCTCTGTCGCCAGGCTGGAGTGCAGTGGTGCTATCTCGGCTCACTGCAACCTCTGCCTC CCAGGTTCAAGCGATTCACCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCGCACAACCACGCCC AGCTAATTTTTGTATTTTTAGTAGAGACGGGGGTTTCATCATACTGCTTAGGATGGTCTCGATCTCTTAA CCTCGTGATCCGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGTCACCATGCCCGGCCGA CCCTGTCTCGTTAAAAAAGAAAGAAAACATCACAGCCTAACTTATAATTATGAAAACTTTTTTTTTTAAT ACGGAGTTTTATTCTGTCACCCAGGGTGGAGTGCAATGGTGTGACTTAGCTCACTGCAGCTTGGATCTTC TAGGCTTAAGTAATCTCCCACCCCATCCTTCTGAGGAGTGAGACTACAGGTGTACACCACCACACCTTGC TAATTTTTTTTTTTAATTATTATTTGTAGAGAGGGAGGTCTCACTATGTTGTGCCGGCTGGTCTCAATCT GCCTTAGGTGATCCTTCTGCCTCAGCCTTCCAAAGTGTTGGATTACAGGTGAGAGCCACCAGGACTGCCT AATTGTAAACACTTAAAAGCGAAATGGGCCGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACATTGGGA GGGTGAGGTGGGCATATCATGAGGTCAGGAGTTTGAGACTAGCCTGGCCAATATGGTGAAACCCCATCTC TAGAAAATATACAAAAATTAGCTAGGCATGGTGGCACGCACCTGTAGTCCCAGCTACTCAGGAGGCTGAG GCAGGAGAATCGCTTGACCTCAGGAAGCAGAGGTTGCAGTGAGCTGAGATTGCACCACTGACTCCAGCCT GGGCAACACAGTGAGACTACGTCTCAGAAAAAAAAAAAAAAAAAAAGCTAAATGTCCTTCAGTTAGTAGT TAAATTATGGCAGATCATACAAGAATTAAGTTAGTTGGTTGGGCGCAGTGGCACACGCCTGTAATCCCAG CACTTTGGGAGGCCGAGGCAGGTGGATCACCTGAGGTTGGGAGTTCGAGACCAGCCTGGCCAACATGGTG AAACCCCGTCTCTACTAAAAATACAAAAATTACCCAGGCATGGTGGCAGGTGCCTGTAATCCCAGCTACT TGGGAGGCTGAGGCAGGAGAATCACTTGAACCCAGGAGGCACAGGTTACACTGAGCTGAGATCATGCCAT TGCAGTCCAGCGTGGGTGATGAGAGAAACTCCGTCTCAAGAAAGAATTAAGTTGGTGTTGATGAGGCCAT GTGGCAATGTGGGAAAATGTATGATGAGGAAAAAACACAGGATGGAAATTATATGTATGCTGTGATGATA TGTAAAACATACCTATGAAGGGCCCGGCACGGTGGCTCACGCCTGTAACCCCAGCACTTTGGGAGGCCGA GGCGGGTGGATCACGGGGTCAGGAGTTTGAGACCAGCTTGGCCAACATGGTGAAATCCCGTCTCTAATTA GCCAGACATGGTGACACGCACCTGTAATCACAGCTACTCAGGAGGCTGAGGCAGGAGAATCTCTTGAACC CAGGAAGCAGAGGTTGCAGTGAGTCGAGACCGTGCCATTGCATTCCAGCCTGGGCAACAAGAGCGAAAGT CCATCTAAAAAAAAAAAACCTATGAACCTATGAAGAAAAGTCCAGAAAGAGAAACTCTAAAATGATTGTT GTAAATGTGATTTGCTCTGCATGGATGAGTAGTAAGGATCATCTTCCTATTATCTACACTTTTTTAAAAA GTTTTAAAGAATTCCAGTTGGTGTTATGATTATGTGAATAAATCAAACCCAATAACTGGACAGCCATCAG TGGTTTGGGCCACTGTGATAAACTTCCAGTATCCAGTGTATGGGGATATATTCCAGTATCCCCATGCCCG TTTTAGGCATATTGATTCCATATTCATCAATAAGCACAAAGCCTGAGCTTATCCATGAAAATAGCAGGGA AAAGAGCTATAAGTTAAGATTTCTTTTTGTTTGTTTGTTTGTTTTGTTTTGTTTGAGACGGAGTCTCGCT TTGTTCCCCGGGCTGGAGTGCAATGGTGTGATCGCTGCTCACTGCAAGCTCCACCTCCCGGGTTCACGCC ATTTTCCTGCCTCAGCCTCTGGAGTAGCTGGGGCTACAGGCGCCCGCCACCACTCCCGGCTAATTTTTTT GTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCT TCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCATTAAGATTTCTTA GTTGTGAAACACCATGAATCCCACCATCATGTGACTTGCCTTGAGAATCTCCCAGAGTCTTGACTATAAA CCATAAGCATTATGGGCAGTGCCTTCTTCCCACCCCTTCCACCTCCACACCTTCATTCCTTCCATTCTGT TCTTCCAGGTGAAGTCATGGGCATTGGGCGTTCATTTGAGGAGGCCTTCCAGAAGGCCCTGCGCATGGTG GATGAGAACTGTGTGGGCTTTGATCACACAGTGAAACCAGTCAGCGATATGGTAAGTAGCTCCCCTCCCC TGGCAATACCCCTAAAATAGACCCTGCTTCTCATCGCCCCCAGACCATGAGCTTGTTACCAGTAACACTA GCAGCAGTCATCATTGGACATTTGCTTTGTTTCCACTTTGCTGAGAATTTTGAGATGTCTCATTAGCACG CAAGGGTGTATTACTAGACTTGTTTTTACAGATGAGGAAACTGAGACATAGGTTATAGAAATTACTCAAA GCCACATAGCCAATGAGAGGTAGACCCAGGATTGGTATCCAGGTTTTTGCAGTTACACAGCCTGTGCTCT GGTGTACAGTTTCCCCTTCCTGAGACAAGAGCAGCTACTTACGCTCAGGCTTTTAGATGGGCTGGCAGTA GCTTCCGTCTGTCTACCCCCTTTCTATCAGGAGTTGGAGACTCCAACAGATAAGCGGATTTTTGTGGTGG CAGCTGCTTTGTGGGCTGGTTATTCAGTGGACCGCCTGTATGAGCTCACACGCATCGACCGCTGGTTCCT GCACCGAATGAAGCGTATCATCGCACATGCCCAGCTGCTAGAACAACACCGTGGACAGCCTTTGCCGCCA GACCTGCTGCAACAGGCCAAGTGTCTTGGCTTCTCAGACAAACAGATTGCCCTTGCAGTTCTGAGGTCAG AGGTGGCAATGAGAGCTTCCGGCTGGGAAATGTGGGGCAGAACCTTTGTATCAGTGAGGGACCCTTGGGA GGGAGGAAGGAGAGTGTGGGAGAGCTTTAGAGGCTTCTGACCTTGGTTCCAAGGATATTTCCTCTCATCT GTGCCCTGGGGTCTCAACCCTCTATCAGTCTGTACCCTACTCTCTGGGCCTGTGTTTCAGACCCTTTTTC TATTTTAGCACAGAGCTGGCTGTTCGCAAGCTGCGTCAGGAACTGGGGATCTGTCCAGCAGTGAAACAGA TTGACACAGTTGCAGCTGAGTGGCCAGCCCAGACAAATTACCTATACCTAACGTATTGGGGCACCACCCA TGACCTCACCTTTCGAACACCTCATGTCCTAGTCCTTGGCTCTGGCGTCTACCGTATTGGCTCTAGCGTT GAATTTGACTGGTGTGCTGTAGGCTGCATCCAGCAGCTCCGAAAGGTCAGAGAGTTCATTTTCTTTCCAC TTTCCTTGCTATTCTGTTCATCTCTAGCAATTGCTTGGCACTAATCCTGGCATTTCCTATTAATTGCCGT CCCTTACTTTGGTCATAGAGCTTTGGGGTGGGGGTCCTTTTAGGCCATCTCTCATGCCCCACACGGTATA TGAATCTCTTCCCCAACACTTTGTACCTCCTTCCCTCCCAAGGCAGGGGTCCTGTACAGCTCTTTCAGAG GAAGCTGTGCTGGCAGTCTCTGAAGTAGGGGCTTTGGCTTAGTTTCTCCACGATTTTCTCCACGATTTTC CTCCCACCTGACTGCTAAGTACCCTTCCCCTCCCTCTTGCAGATGGGATATAAGACCATCATGGTGAACT ATAACCCAGAGACAGTCAGCACCGACTATGACATGTGTGATCGACTCTACTTTGATGAGATCTCTTTTGA GGTGAGGGAGATGGAGGCTTCCTGGTAGCTTGAGTGGCCAGGGTCGAGTAGAACAGCTGGCTGACCTAAG ATTCTTTGAAACTTGGTGGCGGCTGAGGGAAGCAGTGAGCAGGAAGGCTCAGATTCCTGCCCTCTTTTGC TGCCACCACTTGTTTCTCCCCCTGCAACGTAGGTGGTGATGGACATCTATGAGCTCGAGAACCCTGAAGG TGTGATCCTATCCATGGGTGGACAGCTGCCCAACAACATGGCCATGGCGTTGCATCGGCAGCAGTGCCGG GTGCTGGGCACCTCCCCTGAAGCCATTGACTCGGCTGAGAACCGTTTCAAGTTTTCCCGGCTCCTTGACA CCATTGGTATCAGCCAGCCTCAGTGGAGGGAGCTCAGTGACCTCGAGGTGGGCTGGGACCTGGTGGGTTA CCCGGAGGCTGGATGATGCTTGGGGGAAAGTGTGAACAACTCAGCTAAGCTCCCTGCCTCCTGTAGTCTG CTCGCCAATTCTGCCAGACCGTGGGGTACCCCTGTGTGGTGCGCCCCTCCTATGTGCTGAGCGGTGCTGC TATGAATGTGGCCTACACGGATGGAGACCTGGAGCGCTTCCTGAGCAGCGCAGCAGCCGTCTCCAAAGAG CATCCCGTGGTCATCTCCAAGTTCATCCAGGAGGCTAAGGTGGGAGGCTGCAGACAGTGAAGTCTCTGAG GGCATGCTGCCAGCCCTGGAGGAGACTTCCTTCTCTGGTCCAGCAGAATCATAGGCACCAGGGCTGGGAA CAGTGGGCTATGTGGGGCTCGTTAAAGGAAGAGACAATCCTAGAGTAAGTGAGAGAAGAAAGTGGCCCTA TGTCCCACTGTCTGTGTCCCCCCGCTAGGAGATTGACGTGGATGCCGTGGCCTCTGATGGTGTGGTGGCA GCCATCGCCATCTCTGAGCATGTGGAGAATGCAGGTGTGCATTCAGGTGATGCGACGCTGGTGACCCCCC CACAAGATATCACTGCCAAAACCCTGGAGCGGATCAAAGCCATTGTGCATGCTGTGGGCCAGGAGCTACA GGTCACAGGACCCTTCAATCTGCAGCTCATTGCCAAGGTAATAAGGCTAAAGGAAAGAACTAAAGGGCCA CAGCTCTTGCATGTTCTGTGCTGGCCACAGTGCCATGAAGCCCTGCACTGTCTCCTGCCTTCATCCAAGT AGGCAGGGAAGCTGGAGGGAAAGGGCTGTAGCTAGAGCTCATGGTGTTGGGGCTTATGACAGTCAGTGAC CCTGAACCCTGCTCAGTCTGATCCCCCAGAGCTGAGGACGGAGAGGAAGAGTCTAGGCCTATAGATAGTG TCAGCAAGGCCAACCTGCAGAAGGCCTGACCAGTCTTCTCTGCCCCAGGATGACCAGCTGAAAGTTATTG AATGCAACGTACGTGTCTCTCGCTCCTTCCCCTTCGTTTCCAAGACACTGGGTGTGGACCTAGTAGCCTT GGCCACGCGGGTCATCATGGGGGAAGAAGTGGAACCTGTGGGGCTAATGACTGGTTCTGGAGTCGTGGGA GTAAAGGTAAGGAATATCGAAACCCTTGGGGTTAGCAGAAAAATAGCGGGAGAGAGTTCACTCACCACAC AGAGTTGTCAGTATGTAAACCAGGCACTGACTGCAAGGCATTGCCGGATCGTGGGGGTAATGAGGTGGTC ATTGTCCCTTAAGAGCTTACTTTATGGTAATGGGAGGGAAGAGAAGTTGGATCCCCAAAAAAGCTTTGGT ATAGAACAGTCCGTGGTAAAACTACATATTCGACCTGTAAACAGAATGCTGCAGGAGTTCAAGAGACAGG AGGTGCTGCTTCCAAAAGGGGTGATCTGGGAAGGCTTGAGCGAAGGGGTGCTATTTGAATTGAGTTTTGA AGGATGGTTAAGGTTTTTTATTTGCAAGGGCACATCCTAAGCAGAAGCTGAGGGATGACCCCAAGTACGT TTGGAAAGCAGGAGGGCACACAGAGAGGGCAGGCTGACCCTGCCATTCAGATGGGATCAAGCACAGGGTA CTGTGTCCGTCTCTGCTGGTGAGGGAGGAGGTCCTCTCACACCTTGGCCCTCTCTCTTCCCTCCCGCCCC TTTAGGTGCCTCAGTTCTCCTTCTCCCGCTTGGCGGGTGCTGACGTGGTGTTGGGTGTGGAAATGACCAG TACTGGGGAGGTGGCCGGCTTTGGGGAGAGCCGCTGTGAGGCATACCTCAAGGCCATGCTAAGCACTGGC TTTAAGATCCCCAAGAAGAATATCCTGCTGACCATTGGCAGCTATAAGGTATCAGAATCCAGGAGGGCTT CCCGAGGGCCGTGGCTCCCTGGGCCAGGGCTGACCTTGAAATGGAAGACAGGAAGAAAACAATTTCATCC TTCTGTTTGGTTTCAGAACAAAAGCGAGCTGCTCCCAACTGTGCGGCTACTGGAGAGCCTGGGCTACAGC CTCTATGCCAGTCTCGGCACAGCTGACTTCTACACTGAGCATGGCGTCAAGGTGCAGGAACTCTGGCAAC CTACCCCACTGCTGCCCTTCCCCAAGGGGGTGAAAATACTGCACCAAAGAATTATCTGGGCTGGGCACGG TGGCATATACCTGTAGTCCCAGATACTCAGGAGGCTAAGGCAGGAGAATCTCTTGAGCCCAGGAGGTAGA GGCTGCAGTGAGCTGCGAGTGTGCAGTGAGTGCACCACTGCACTCCAGCTTGGGAAACAGTGAGATGCTG TCTCAAAAAAAAAAAAAACAAAGAATTATCTCCTATTCCCCTGCTTTTATTATTACCATTATACTAGTAA GCTATATTCCATGCAGAAAGCAGAATACACAGGAAGCAAAGAGAAAAGTCTCTTAAAATCTCTGTACCAC TGTTCTGATATTTTTCCTTCCAGGATTTTCTCTGTGTACATGTGTGTGAGCTCATACTGCACCTAGTCCT TGGTAACCCATCTTACTTAGTGTAGATATCTTTCCTGCCAAGAAATACACTTTGCCAGTATCAAATAGAG GCAGCCCTCAGTGCCCACCCTATGGGTCCTCAGTCTCCTCATCATGGGCTCCTGGGCCAGCTCCTCTCCC TTAAGGCTAGCCTTCCTGACCGCTGCCAGACAGCTTGGCCCTGACCTTGACTCCGGGTTGGCAGGTAACA GCTGTGGACTGGCACTTTGAGGAGGCTGTGGATGGTGAGTGCCCACCACAGCGGAGCATCCTGGAGCAGC TAGCTGAGAAAAACTTTGAGCTGGTGATTAACCTGTCAATGCGTGGAGCTGGGGGCCGGCGTCTCTCTTC CTTTGTCACCAAGGGCTACCGCACCCGACGCTTGGCCGCTGACTTCTCCGTGCCCCTAATCATCGATATC AAGTGCACCAAACTCTTTGTGGAGGTAACTGAGACCCATGTGCTGGGAGGGAGACTGCCAGTGTTGATGG GAAGAAGAAAGAGGGAGGAGTGAGTATGGAACAGCCATGCTAGTAATAAAGCTTTGTGGCTACAGAGGGA GAGATGGTGGGTATAGAGTGTGCAGAGCCTGGTTTATGGGAAAACCACATCTCTCCCTACAACTCCCAGG ATCACCCTTCCCTTAAAGCTGACTGCTTTCCACTTGCAGGCCCTAGGCCAGATCGGGCCAGCCCCTCCTT TGAAGGTGCATGTTGACTGTATGACCTCCCAAAAGCTTGTGCGACTGCCGGGTAAGTCTTTGGGGAGAAC TTGGCTTCTGAACACTGGCAGCCCCTGGCATAGAGACCTGCAGTGTGGTGAAGGATGGCTGGGGGGCCCA CTCTTTGTCCTGGACTGCACAGACTGTGAAGACCCCAGAATGTTTCTCACTCTTTCATTCCTTAATCCAC AGTGTCCACAGTGGCCTTGTCTGAGGAATTTTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTTACTCCAT CGCCCAGGTTGGAGTGCAGTGGTGTGTGATATCGGCTCACTGCAACCTCCGCCTCCCAGGTTCAAGCGAT TTTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGTGTGTGCTACCACACCAGGCTAATTTTTGTGT TTTTAGTAGAGACGGGGTTTCACCATGTTGGTCAGGTTGGTCTCGAACTCCTGATCTCAGGTGATCTGCC CACCTCGGCCTCCCAAAGTGCTAGGATTACAGGCGTGAGCCACCATGTCCAGCTCACCCTTCCTATTTCT GAATCTTCCTGTAATCTTGCTGCTTCCATTTTCTCCCAGGATTGATTGATGTCCATGTGCACCTGCGGGA ACCAGGTGGGACACATAAGGAGGACTTTGCTTCAGGCACAGCCGCTGCCCTGGCTGGGGGTATCACCATG GTGTGTGCCATGCCTAATACCCGGCCCCCCATCATTGACGCCCCTGCTCTGGCCCTGGCCCAGAAGGTGA GCCACTGCACTCTTCCTGGTATTGGAGACCCATATGCCCCTACCAGCCACCCTTGCTTCCCTGAGCCCTT TTCCTTCTGCCCCGCCCTATGGGCCCAGGCCACTGGTGCCAGGCTAGCCTGTGTGGGCATGGGTGCCAGT GAGCCTTACCTCTGTGTATCCTCTCCAGCTGGCAGAGGCTGGCGCCCGGTGCGACTTTGCGCTATTCCTT GGGGCCTCGTCTGAAAATGCAGGAACCTTGGGCACCGTGGCCGGGTCTGCAGCCGGGCTGAAGCTTTACC TCAATGAGACCTTCTCTGAGCTGCGGCTGGACAGCGTGGTCCAGTGGATGGAGGTAGGGAGTGTGCATGT GGCAGGAGGCCACCACCCAGTGTCTCCTGGCTTGTGGGCCCCTGCCTAAGTGGGCTGGTAGCAGTGAGGA TTCAGGGGAGCTCCTGGGGACTCTGGGCTCTGATGAGCACAGTCAGAGATTCTGCACACTCCTTCATCAG TTCTTTCTGCTCCCAGCATTTCGAGACATGGCCCTCCCACCTCCCCATTGTGGCTCACGCAGAGCAGCAA ACCGTGGCTGCTGTCCTCATGGTGGCTCAGCTCACTCAGCGCTCAGTGCACATATGTCACGTGGCACGGA AGGAGGAGGTAAGAGTACACCTGAGATCCTGCTGTCCCTGTTGCTTTCCCAGTAACACCAAAGGTCAGGG TAGTCCTTAGGGGCAGGAGACAGCAGGAGGAGAGTCTGGAGACAGCAGGAGGAGGGTCTCGAGCCAGCAC CCTTGCAGGTCTACATCATCATTTTTTGAGCAGGGATGTTGGCCATTGGGACTTTGTGTAGGGCAAGGCA TATGGGTGGTGCCTCTTCTGGATCTTCCCATTGTTCCCCAGATCCTGCTAATTAAAGCTGCAAAGGCACG GGGCTTGCCAGTGACCTGCGAGGTGGCTCCCCACCACCTGTTCCTAAGCCATGATGACCTGGAGCGCCTG GGGCCTGGGAAGGGGGAGGTCCGGCCTGAGCTTGGCTCCCGCCAGGATGTGGAAGCCCTGTGGGAGAACA TGGCTGTCATCGACTGCTTTGCCTCAGACCATGGTGAGAGAATCCAGCATGTACCTCCTCTGCCCAGTGG GGCTTGTGGGACAGCCCTAGCAAGAAAATGGGAAGCAGGCCAGGCCTCAGGACTCTACTAGGACAGGGTC TTGATCCGTATGGGACCCTAGCCTCTAGGGTACCTGGTCTGTGATAGGTGCCTGATAAATACTTGTTGAA AGAATGAATGAGCCAGTGAGTAGAACTGCAAGTGAAAGAATACATGGGTAAAAGTGTGGGCTCCAGAAGA TGGCAGCAGTCCTGTTGCCCTTGTTTCTAGTTCCCAGAAAAAATGAGCATTGGGAGTGGTAGTGAGCATA AGGAGGTTGTTGGAAGTGCAGTCCTGGGGTGTGAGTGACTTCCTAGACATGGAGGTGATTGGTCCTGAGG GTAATGGCTTTCTTTCTCCCAGCTCCCCATACCTTGGAGGAGAAGTGTGGGTCCAGGCCCCCACCTGGGT TCCCAGGGTTAGAGACCATGCTGCCACTACTCCTGACGGCTGTAAGCGAGGGCCGGCTCAGCCTGGACGA CCTGCTGCAGCGATTGCACCACAATCCTCGGCGCATCTTTCACCTGCCCCCGCAGGAGGACACCTATGTG GAGGTGTGGGGATGAGGCCCAGAGCAGGAGGGGGGCTCTCCAGCCCTAGGATATGTTCTCTGGGGATCCT TTCCCTAGCATAACCCATGTCCTCTGGGCAGGTGGATCTGGAGCATGAGTGGACAATTCCCAGCCACATG CCCTTCTCCAAGGCCCACTGGACACCTTTTGAAGGGCAGAAAGTGAAGGGCACCGTCCGCCGTGTGGTCC TGCGAGGGGAGGTTGCCTATATCGATGGGCAGGTACGCAAGTAGCCCCTGCCTGATCTCAGTAGTGCCCT CTTCTGCACCACGTTCATTTCTTCCCTTCCCAGCACATCTACACTGTCCCACTATGTGCACCACTGCCCT GGACCAGGGGTTGGGGGCACAGCTCCCCCAAGGTGCTTTTTGTCCTTGCTGACATCTACCCCTTTAGGAC CTGAGTTCTCTCTGCTCCCTCCTGAGTGCCCTGCCTTCTGCCTGCAGGTTCTGGTACCCCCGGGCTATGG ACAGGATGTACGGAAGTGGCCACAGGGGGCTGTTCCTCAGCTCCCACCCTCAGCCCCTGCCACTAGTGAG ATGACCACGGTATCCACACTACTGGGCTAGGGGGCTGGGAGGTGTTAGTCTCAGGGCAGGATGAACAGCT TGAACATTTTCATTGGTGGTTCAGGAACAATTGGGGTTTTCTTGAGGGACTGAATTTGAAGTGGGGTTGG GTCAATTATTTTTTTAAAATGCTGGGCCAGGCCAGATGTGGTGGCTCACACTTGTAATCCCAGCACTTTG GGAGGCCAAGGCAGGCGGATCATCTGAGGTCAGGAGTTTAAGACCAGCCTAGCCAACATGGTGAAACCCC ATCTCTACTAAAAATAAAAAAATTAGCCAGGCGTGGTGGTGCACATCTGTAATCCCAGCTACTTGGGAGG CTGAGGCAGGAGAATTGCTTGAACCCAGAAGGTCACGCCACTGCACTCCAGCCTGAGCGACAGAACGAGA CTCCGTCTCAAAAGAAAAAAAAAAAAACAACTCTGGGCCAACGTTATCCCTCCAGACACCTGAAAGACCC CGCCGTGGCATCCCAGGGCTTCCTGATGGCCGCTTCCATCTGCCGCCCCGAATCCATCGAGCCTCCGACC CAGGTTTGCCAGGTAAGAGTGGGGTTCCTGTGACTCAGAGACTGTGTAGGGACAGGATCCACTTCTTCCC AGTGCCTCGCCTTTCTCTACTTACATGTCCTCCTCTCCATCCCTTTATCCTCGTCTGATCTGCCGTGCCA TCCTTTGCCTAAACAAGTCTCCCCGGTGTGAGTAGACATCTCACAGCTTCTCACATGCCCTTTTTTGTTG TGGGCAGCTGTGTTCCTCCGCCCAGGAGCTGGGATCCCACGGGGCAGCAGAGCGTGGGGTAAATCCAGGT TGTTGGTTGGTGTGAGTCTGGCCGTTCCTCTTGCCTAGGATGCCTTTGCCAACTGGGAGAGCCCCGGGAG GGCACCACTGCTCCCATACAACACAGCCCCATGGGAAGCCACCTGTCTGTCCCCAGAGCTGCTGCAGTCC CCTGCCCTCCCCTAACCTGCTATATTACTGTGTTGTGAATTGGTTTAACATATACACTGTGATTCAGAGT TCCTGGGAATATGGGGTTTCTTTCCAAACCTCAGCCATAAATGTATATCTGTCCTCTTGTCCTGTTTGCA GCTGAGGAGCCAAAGGAGAAGTCCTCTCGGAAGGTAGCCGAGCCAGGTGAGACTCCACCCTGACACACAC TCACCTCGGGGACCTCTGATCTGGCCTTGGTAGGAGGAACCCTCTGACCAGCCTTTTCTGCCCCATCCCT CACTGCAGAGCTGATGGGAACCCCTGATGGCACCTGCTACCCTCCACCACCAGTACCGAGACAGGCATCT CCCCAGAACCTGGGGACCCCTGGCTTGCTGCACCCCCAGACCTCACCCCTGCTGCACTCATTAGTGGGCC AACATATCCTGTCCGTCCAGCAGTTCACCAAGGATCAGGTGCCTGGGGCAGGGAGGATGGGACCACCCAG AGCTTTGAGGATTTGGAAAGCTGGGGCTAGGACCTTTCTAGCTAACTTGGGCTCTTTCTTAGATGTCTCA CCTGTTCAATGTGGCACACACACTGCGTATGATGGTGCAGAAGGAGCGGAGCCTCGACATCCTGAAGGTC AGGATCAGGGCCGGGGGTAGGGTCCAGGCCATCGCCTGCCCTTGGGCCGCATCAGCGCAGGGCCGCGCAG TGGTCAGAGTGGGTCTTCCTCCCCCTGCCATCCCGTCCCCTTATGCTAGTCCATCCCTCTGCTGCTGTAG ATCTTCCCCCACGTTTTCCCTCCCCAAAGCAGGATTTAGCTGGCTGGGGAGGCCCTGAGCATGAGACCAT CGCCCCACTAGTGGGGTCTTCTGGTCTGGGCTGCTGCAATCATGGGAGAGAGCTAGGGTGTGTCCTCCTT TCCCAGCTCGTTCAGACACTTAATGATGGGTGGTTTTCTGGAGGCAGAGCCTTTAGCTCAGAGTGACACC AGTGGTGGAAACGTCAAGGCTCTGACAGGTCACAGGGGAGGTTTGGGTGCAGAAGGGTCCTCACAGCACC CCTCAAGTGTCAGTTGGGGTGGTGGTGCCTAGCTGGGGTTTCCCCAGGGTGGACACGCATACGTACACCT TCCATCTTGCTCTTTCCCTAGGGGAAGGTCATGGCCTCCATGTTCTATGAAGTGAGCACACGGACCAGCA GCTCCTTTGCAGCAGCCATGGCCCGGCTGGGAGGTGCTGTGCTCAGCTTCTCGGAAGCCACATCGTCCGT CCAGAAGGGCGAATCCCTGGCTGACTCCGTGCAGACCATGAGCTGCTATGCCGACGTCGTCGTGCTCCGG CACCCCCAGCCTGGAGCAGTGGAGGTGAGGCCAGCCTGGGTACTGAGATGGGGTTAAGAAGGCTGGACCC AGGGGCATGAGAACCCTTCTGCCCACGTTTTCTGTGTTTTGGGCCAGATGAGTGAGGGGACCCCAGAAGA GGGGGACTGGCAGTTGGGGGGCCTCTGAGCTGCAAAAGACAGGATTTTCCCCTTTTTTCCAGCTGGCCGC CAAGCACTGCCGGAGGCCAGTGATCAATGCTGGGGATGGGGTCGGAGAGCACCCCACCCAGGCCCTGCTG GACATCTTCACCATCCGTGAGGAGCTGGGAACTGTCAATGGCATGACGGTGAGGGTGGTGGCAGGGTTTG GATCCCTGCCAGGGGACGATCTAGAGAGGGAGGCAGGAAGTGGTTACCCCGGTACAGGACAGCTGCATCA AGGAGGCCTTCATTCTGCTCCAGAGGCTTTTAAAAGCTTGGAAATGATGTCGGGGGGCACTCAGTCTGGG ATCCCTGTGGTGACTGGATTCCTCTCCTAGATCACGATGGTGGGTGACCTGAAGCACGGACGCACAGTAC ATTCCCTGGCCTGCCTGCTCACCCAGTATCGTGTCAGCCTGCGCTACGTGGCACCTCCCAGCCTGCGCAT GCCACCCACTGTGCGGGCCTTCGTGGCCTCCCGCGGCACCAAGCAGGTGAGACCCTCACAGCCCTGCCTG GAAGCCATGGAGATGTGGGTTGGGCAGTCAGAGCCCAGCGCTGCATCCACCATGGCTCTCCTCACCCTCC AGGAGGAATTCGAGAGCATTGAGGAGGCGCTGCCTGACACTGATGTGCTCTACATGACTCGAATCCAGAA GGAACGATTTGGCTCTACCCAGGAGTACGAAGCTGTGAGTGCTGGGCTTGAGGAAGAAGCCAGGGCTGCT GCCGTAGGGCATCAGATATGAGGACAGAAAGGCTGGGCTGAGGGCTGGGTCAGAGCTGTTAAACTTCACA TCTGTCAATTGCCATAGCTGCATGTGGGTGTGGAGGGGACCCCAGTGGAGCCCAGACTTGTGTCCTCTGT AGCCACTCCTACCCCAAGGCACTAATGGGGACCCCATCTGCTTTGCAGTGCTTTGGTCAGTTCATCCTCA CTCCCCACATCATGACCCGGGCCAAGAAGAAGATGGTGGTGATGCACCCGATGCCCCGTGTCAACGAGAT AAGGTGGTGCAGCATCAGAGTCAGAGACTGCCTCGGGGCTGGTGGACGGGAGGAGACTTAGTCCTGGACA AGCCATCCATGGGCTGCACGATAACACTTCCTTTTTTTTTTTTTTTTTTTTTGCAGCGTGGAAGTGGACT CGGATCCCCGCGCAGCCTACTTCCGCCAGGCTGAGAACGGCATGTACATCCGCATGGCTCTGTTAGCCAC CGTGCTGGGCCGTTTCTAGGGCCTGGCTTCCTCAGCCTCTTCTCTTTAGGCCCAGCTGCTGGGCAAGGAA TTCCAGTGCCTCCTACGGGGGCAGCACACTTAGATATTCCTGGACATCCAGATAGCTCACATGTGCTGAC CACACTTCAGGCTCTGGACTGGAGCTCTCTGGCATGGGGGTGGGGCCTCAGATGCTGGGGCCCAGTCTGC CCCATCTTCATTCCTGCACCTTAAACCTGTACAGTCATTTTTCTACTGACTTAATAAACAGCCGAGCTGT CCCTTGATGCTGA Download Select all
Length	26403
OMIM ID	114010
HGNC ID	HGNC:1424
Unigene ID	Hs.377010
Ensembl ID	ENSG00000084774
PharmGKB ID	PA26023

mRNA Information

mRNA ID	NM_004341.4
Exon	join(1..244,488..627,3829..3958,4805..4947,5130..5271, 5477..5648,6174..6359,6528..6640,6956..7101,7356..7487, 7621..7854,8316..8537,8742..8930,9136..9260,9443..9573, 14079..14191,14591..14835,15059..15305,15653..15751, 15923..16147,16237..16419,16619..16837,17129..17296, 17856..18038,18147..18251,18895..19134,19360..19441, 19990..20156,20329..20493,20667..20798,21042..21243, 21653..21843,21942..22082,22308..22409,22876..22972, 23522..23566,23669..23838,23933..24007,24522..24734, 24913..25038,25231..25386,25483..25584,25809..25903, 26027..26397)
mRNA Sequence	>gi\|807045908\|ref\|NM_004341.4\| Homo sapiens carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase (CAD), transcript variant 1, mRNA GCGCGCCCGAGGCTCCTACGCTGCCGCGCCCGGCTTCTCTCCAGCGCCCCGCGCCGTTAGCCACGTGGAC CGACTCCGGCGCGCCGTCCTCACGTGGTTCCAGTGGAGTTTGCAGTCCTTCCCGCTTCTCCGTACTCGCC CCCGCCTCTGAGCTCCCTTCCCATGGCGGCCCTAGTGTTGGAGGACGGGTCGGTCCTGCGGGGCCAGCCC TTTGGGGCCGCCGTGTCGACTGCCGGGGAAGTGGTGTTTCAAACCGGCATGGTCGGCTACCCCGAGGCCC TCACTGATCCCTCCTACAAGGCACAGATCTTAGTGCTCACCTATCCTCTGATCGGCAACTATGGCATCCC CCCAGATGAAATGGATGAGTTCGGTCTCTGCAAGTGGTTTGAATCCTCGGGCATCCACGTAGCAGCACTG GTAGTGGGAGAGTGCTGTCCTACTCCCAGCCACTGGAGTGCCACCCGCACCCTGCATGAGTGGCTGCAGC AGCATGGCATCCCTGGCTTGCAAGGAGTAGACACTCGGGAGCTGACCAAGAAGTTGCGGGAACAGGGGTC TCTGCTGGGGAAGCTGGTCCAGAATGGAACAGAACCTTCATCCCTGCCATTCTTGGACCCCAATGCCCGC CCCCTGGTACCAGAGGTCTCCATTAAGACTCCACGGGTATTCAATACAGGGGGTGCCCCTCGGATCCTTG CTTTGGACTGTGGCCTCAAGTATAATCAGATCCGATGCCTCTGCCAGCGTGGGGCTGAGGTCACTGTGGT ACCCTGGGACCATGCACTAGACAGCCAAGAGTATGAGGGTCTCTTCTTAAGTAATGGGCCTGGTGACCCT GCCTCCTATCCCAGTGTCGTATCCACACTGAGCCGTGTTTTATCTGAGCCTAATCCCCGACCTGTCTTTG GGATCTGCCTGGGACACCAGCTATTGGCCTTAGCCATTGGGGCCAAGACTTACAAGATGAGATATGGGAA CCGAGGCCATAACCAGCCCTGCTTGTTGGTGGGCTCTGGGCGCTGCTTTCTGACATCCCAGAACCATGGG TTTGCTGTGGAGACAGACTCACTGCCAGCAGACTGGGCTCCTCTCTTCACCAACGCCAATGATGGTTCCA ATGAAGGCATTGTGCACAACAGCTTGCCTTTCTTCAGTGTCCAGTTTCACCCAGAGCACCAAGCTGGCCC TTCAGATATGGAACTGCTTTTCGATATCTTTCTGGAAACTGTGAAAGAGGCCACAGCTGGGAACCCTGGG GGCCAGACAGTTAGAGAGCGGCTGACTGAGCGCCTCTGTCCCCCTGGGATTCCCACTCCCGGCTCTGGAC TTCCACCACCACGAAAGGTTCTGATCCTGGGCTCAGGGGGCCTCTCCATTGGCCAAGCTGGAGAATTTGA CTACTCGGGCTCTCAGGCAATTAAGGCCCTGAAGGAGGAAAACATCCAGACGTTGCTGATCAACCCCAAT ATTGCCACAGTGCAGACCTCCCAGGGGCTGGCCGACAAGGTCTATTTTCTTCCCATAACACCTCATTATG TAACCCAGGTGATACGTAATGAACGCCCCGATGGTGTGTTACTGACTTTTGGGGGCCAGACTGCTCTGAA CTGTGGTGTGGAGCTGACCAAGGCCGGGGTGCTGGCTCGGTATGGGGTCCGGGTCCTGGGCACACCAGTG GAGACCATTGAGCTGACCGAGGATCGACGGGCCTTTGCTGCCAGAATGGCAGAGATCGGAGAGCATGTGG CCCCGAGCGAGGCAGCAAATTCTCTTGAACAGGCCCAGGCAGCCGCTGAACGGCTGGGGTACCCTGTGCT AGTGCGTGCAGCCTTTGCCCTGGGTGGCCTGGGCTCTGGCTTTGCCTCTAACAGGGAGGAGCTCTCTGCT CTCGTGGCCCCAGCTTTTGCCCATACCAGCCAAGTGCTAGTAGACAAGTCTCTGAAGGGATGGAAGGAGA TTGAGTACGAGGTGGTGAGAGACGCCTATGGCAACTGTGTCACGGTGTGTAACATGGAGAACTTGGACCC ACTGGGCATCCACACTGGTGAGTCCATAGTGGTGGCCCCTAGCCAGACACTGAATGACAGGGAGTATCAG CTCCTGAGGCAGACAGCTATCAAGGTGACCCAGCACCTGGGAATTGTTGGGGAGTGCAATGTGCAGTATG CCTTGAACCCTGAGTCTGAGCAGTATTACATCATTGAAGTGAATGCCAGGCTCTCTCGCAGCTCTGCCCT GGCCAGTAAGGCCACAGGTTATCCACTGGCTTATGTGGCAGCCAAGCTAGCATTGGGCATCCCTTTGCCT GAGCTCAGGAACTCTGTGACAGGGGGTACAGCAGCCTTTGAACCCAGCGTGGATTATTGTGTGGTGAAGA TTCCTCGATGGGACCTTAGCAAGTTCCTGCGAGTCAGCACAAAGATTGGGAGCTGCATGAAGAGCGTTGG TGAAGTCATGGGCATTGGGCGTTCATTTGAGGAGGCCTTCCAGAAGGCCCTGCGCATGGTGGATGAGAAC TGTGTGGGCTTTGATCACACAGTGAAACCAGTCAGCGATATGGAGTTGGAGACTCCAACAGATAAGCGGA TTTTTGTGGTGGCAGCTGCTTTGTGGGCTGGTTATTCAGTGGACCGCCTGTATGAGCTCACACGCATCGA CCGCTGGTTCCTGCACCGAATGAAGCGTATCATCGCACATGCCCAGCTGCTAGAACAACACCGTGGACAG CCTTTGCCGCCAGACCTGCTGCAACAGGCCAAGTGTCTTGGCTTCTCAGACAAACAGATTGCCCTTGCAG TTCTGAGCACAGAGCTGGCTGTTCGCAAGCTGCGTCAGGAACTGGGGATCTGTCCAGCAGTGAAACAGAT TGACACAGTTGCAGCTGAGTGGCCAGCCCAGACAAATTACCTATACCTAACGTATTGGGGCACCACCCAT GACCTCACCTTTCGAACACCTCATGTCCTAGTCCTTGGCTCTGGCGTCTACCGTATTGGCTCTAGCGTTG AATTTGACTGGTGTGCTGTAGGCTGCATCCAGCAGCTCCGAAAGATGGGATATAAGACCATCATGGTGAA CTATAACCCAGAGACAGTCAGCACCGACTATGACATGTGTGATCGACTCTACTTTGATGAGATCTCTTTT GAGGTGGTGATGGACATCTATGAGCTCGAGAACCCTGAAGGTGTGATCCTATCCATGGGTGGACAGCTGC CCAACAACATGGCCATGGCGTTGCATCGGCAGCAGTGCCGGGTGCTGGGCACCTCCCCTGAAGCCATTGA CTCGGCTGAGAACCGTTTCAAGTTTTCCCGGCTCCTTGACACCATTGGTATCAGCCAGCCTCAGTGGAGG GAGCTCAGTGACCTCGAGTCTGCTCGCCAATTCTGCCAGACCGTGGGGTACCCCTGTGTGGTGCGCCCCT CCTATGTGCTGAGCGGTGCTGCTATGAATGTGGCCTACACGGATGGAGACCTGGAGCGCTTCCTGAGCAG CGCAGCAGCCGTCTCCAAAGAGCATCCCGTGGTCATCTCCAAGTTCATCCAGGAGGCTAAGGAGATTGAC GTGGATGCCGTGGCCTCTGATGGTGTGGTGGCAGCCATCGCCATCTCTGAGCATGTGGAGAATGCAGGTG TGCATTCAGGTGATGCGACGCTGGTGACCCCCCCACAAGATATCACTGCCAAAACCCTGGAGCGGATCAA AGCCATTGTGCATGCTGTGGGCCAGGAGCTACAGGTCACAGGACCCTTCAATCTGCAGCTCATTGCCAAG GATGACCAGCTGAAAGTTATTGAATGCAACGTACGTGTCTCTCGCTCCTTCCCCTTCGTTTCCAAGACAC TGGGTGTGGACCTAGTAGCCTTGGCCACGCGGGTCATCATGGGGGAAGAAGTGGAACCTGTGGGGCTAAT GACTGGTTCTGGAGTCGTGGGAGTAAAGGTGCCTCAGTTCTCCTTCTCCCGCTTGGCGGGTGCTGACGTG GTGTTGGGTGTGGAAATGACCAGTACTGGGGAGGTGGCCGGCTTTGGGGAGAGCCGCTGTGAGGCATACC TCAAGGCCATGCTAAGCACTGGCTTTAAGATCCCCAAGAAGAATATCCTGCTGACCATTGGCAGCTATAA GAACAAAAGCGAGCTGCTCCCAACTGTGCGGCTACTGGAGAGCCTGGGCTACAGCCTCTATGCCAGTCTC GGCACAGCTGACTTCTACACTGAGCATGGCGTCAAGGTAACAGCTGTGGACTGGCACTTTGAGGAGGCTG TGGATGGTGAGTGCCCACCACAGCGGAGCATCCTGGAGCAGCTAGCTGAGAAAAACTTTGAGCTGGTGAT TAACCTGTCAATGCGTGGAGCTGGGGGCCGGCGTCTCTCTTCCTTTGTCACCAAGGGCTACCGCACCCGA CGCTTGGCCGCTGACTTCTCCGTGCCCCTAATCATCGATATCAAGTGCACCAAACTCTTTGTGGAGGCCC TAGGCCAGATCGGGCCAGCCCCTCCTTTGAAGGTGCATGTTGACTGTATGACCTCCCAAAAGCTTGTGCG ACTGCCGGGATTGATTGATGTCCATGTGCACCTGCGGGAACCAGGTGGGACACATAAGGAGGACTTTGCT TCAGGCACAGCCGCTGCCCTGGCTGGGGGTATCACCATGGTGTGTGCCATGCCTAATACCCGGCCCCCCA TCATTGACGCCCCTGCTCTGGCCCTGGCCCAGAAGCTGGCAGAGGCTGGCGCCCGGTGCGACTTTGCGCT ATTCCTTGGGGCCTCGTCTGAAAATGCAGGAACCTTGGGCACCGTGGCCGGGTCTGCAGCCGGGCTGAAG CTTTACCTCAATGAGACCTTCTCTGAGCTGCGGCTGGACAGCGTGGTCCAGTGGATGGAGCATTTCGAGA CATGGCCCTCCCACCTCCCCATTGTGGCTCACGCAGAGCAGCAAACCGTGGCTGCTGTCCTCATGGTGGC TCAGCTCACTCAGCGCTCAGTGCACATATGTCACGTGGCACGGAAGGAGGAGATCCTGCTAATTAAAGCT GCAAAGGCACGGGGCTTGCCAGTGACCTGCGAGGTGGCTCCCCACCACCTGTTCCTAAGCCATGATGACC TGGAGCGCCTGGGGCCTGGGAAGGGGGAGGTCCGGCCTGAGCTTGGCTCCCGCCAGGATGTGGAAGCCCT GTGGGAGAACATGGCTGTCATCGACTGCTTTGCCTCAGACCATGCTCCCCATACCTTGGAGGAGAAGTGT GGGTCCAGGCCCCCACCTGGGTTCCCAGGGTTAGAGACCATGCTGCCACTACTCCTGACGGCTGTAAGCG AGGGCCGGCTCAGCCTGGACGACCTGCTGCAGCGATTGCACCACAATCCTCGGCGCATCTTTCACCTGCC CCCGCAGGAGGACACCTATGTGGAGGTGGATCTGGAGCATGAGTGGACAATTCCCAGCCACATGCCCTTC TCCAAGGCCCACTGGACACCTTTTGAAGGGCAGAAAGTGAAGGGCACCGTCCGCCGTGTGGTCCTGCGAG GGGAGGTTGCCTATATCGATGGGCAGGTTCTGGTACCCCCGGGCTATGGACAGGATGTACGGAAGTGGCC ACAGGGGGCTGTTCCTCAGCTCCCACCCTCAGCCCCTGCCACTAGTGAGATGACCACGACACCTGAAAGA CCCCGCCGTGGCATCCCAGGGCTTCCTGATGGCCGCTTCCATCTGCCGCCCCGAATCCATCGAGCCTCCG ACCCAGGTTTGCCAGCTGAGGAGCCAAAGGAGAAGTCCTCTCGGAAGGTAGCCGAGCCAGAGCTGATGGG AACCCCTGATGGCACCTGCTACCCTCCACCACCAGTACCGAGACAGGCATCTCCCCAGAACCTGGGGACC CCTGGCTTGCTGCACCCCCAGACCTCACCCCTGCTGCACTCATTAGTGGGCCAACATATCCTGTCCGTCC AGCAGTTCACCAAGGATCAGATGTCTCACCTGTTCAATGTGGCACACACACTGCGTATGATGGTGCAGAA GGAGCGGAGCCTCGACATCCTGAAGGGGAAGGTCATGGCCTCCATGTTCTATGAAGTGAGCACACGGACC AGCAGCTCCTTTGCAGCAGCCATGGCCCGGCTGGGAGGTGCTGTGCTCAGCTTCTCGGAAGCCACATCGT CCGTCCAGAAGGGCGAATCCCTGGCTGACTCCGTGCAGACCATGAGCTGCTATGCCGACGTCGTCGTGCT CCGGCACCCCCAGCCTGGAGCAGTGGAGCTGGCCGCCAAGCACTGCCGGAGGCCAGTGATCAATGCTGGG GATGGGGTCGGAGAGCACCCCACCCAGGCCCTGCTGGACATCTTCACCATCCGTGAGGAGCTGGGAACTG TCAATGGCATGACGATCACGATGGTGGGTGACCTGAAGCACGGACGCACAGTACATTCCCTGGCCTGCCT GCTCACCCAGTATCGTGTCAGCCTGCGCTACGTGGCACCTCCCAGCCTGCGCATGCCACCCACTGTGCGG GCCTTCGTGGCCTCCCGCGGCACCAAGCAGGAGGAATTCGAGAGCATTGAGGAGGCGCTGCCTGACACTG ATGTGCTCTACATGACTCGAATCCAGAAGGAACGATTTGGCTCTACCCAGGAGTACGAAGCTTGCTTTGG TCAGTTCATCCTCACTCCCCACATCATGACCCGGGCCAAGAAGAAGATGGTGGTGATGCACCCGATGCCC CGTGTCAACGAGATAAGCGTGGAAGTGGACTCGGATCCCCGCGCAGCCTACTTCCGCCAGGCTGAGAACG GCATGTACATCCGCATGGCTCTGTTAGCCACCGTGCTGGGCCGTTTCTAGGGCCTGGCTTCCTCAGCCTC TTCTCTTTAGGCCCAGCTGCTGGGCAAGGAATTCCAGTGCCTCCTACGGGGGCAGCACACTTAGATATTC CTGGACATCCAGATAGCTCACATGTGCTGACCACACTTCAGGCTCTGGACTGGAGCTCTCTGGCATGGGG GTGGGGCCTCAGATGCTGGGGCCCAGTCTGCCCCATCTTCATTCCTGCACCTTAAACCTGTACAGTCATT TTTCTACTGACTTAATAAACAGCCGAGCTGTCCCTTGATGCTGAAAAAAAAAAAAAAAAAA Download Select all
Length	7131

CDS Information

Location	163..6840
CDS Sequence	>lcl\|NM_004341.4_cds_NP_004332.2_1 [gene=CAD] [protein=CAD protein isoform 1] [protein_id=NP_004332.2] [location=163..6840] ATGGCGGCCCTAGTGTTGGAGGACGGGTCGGTCCTGCGGGGCCAGCCCTTTGGGGCCGCCGTGTCGACTG CCGGGGAAGTGGTGTTTCAAACCGGCATGGTCGGCTACCCCGAGGCCCTCACTGATCCCTCCTACAAGGC ACAGATCTTAGTGCTCACCTATCCTCTGATCGGCAACTATGGCATCCCCCCAGATGAAATGGATGAGTTC GGTCTCTGCAAGTGGTTTGAATCCTCGGGCATCCACGTAGCAGCACTGGTAGTGGGAGAGTGCTGTCCTA CTCCCAGCCACTGGAGTGCCACCCGCACCCTGCATGAGTGGCTGCAGCAGCATGGCATCCCTGGCTTGCA AGGAGTAGACACTCGGGAGCTGACCAAGAAGTTGCGGGAACAGGGGTCTCTGCTGGGGAAGCTGGTCCAG AATGGAACAGAACCTTCATCCCTGCCATTCTTGGACCCCAATGCCCGCCCCCTGGTACCAGAGGTCTCCA TTAAGACTCCACGGGTATTCAATACAGGGGGTGCCCCTCGGATCCTTGCTTTGGACTGTGGCCTCAAGTA TAATCAGATCCGATGCCTCTGCCAGCGTGGGGCTGAGGTCACTGTGGTACCCTGGGACCATGCACTAGAC AGCCAAGAGTATGAGGGTCTCTTCTTAAGTAATGGGCCTGGTGACCCTGCCTCCTATCCCAGTGTCGTAT CCACACTGAGCCGTGTTTTATCTGAGCCTAATCCCCGACCTGTCTTTGGGATCTGCCTGGGACACCAGCT ATTGGCCTTAGCCATTGGGGCCAAGACTTACAAGATGAGATATGGGAACCGAGGCCATAACCAGCCCTGC TTGTTGGTGGGCTCTGGGCGCTGCTTTCTGACATCCCAGAACCATGGGTTTGCTGTGGAGACAGACTCAC TGCCAGCAGACTGGGCTCCTCTCTTCACCAACGCCAATGATGGTTCCAATGAAGGCATTGTGCACAACAG CTTGCCTTTCTTCAGTGTCCAGTTTCACCCAGAGCACCAAGCTGGCCCTTCAGATATGGAACTGCTTTTC GATATCTTTCTGGAAACTGTGAAAGAGGCCACAGCTGGGAACCCTGGGGGCCAGACAGTTAGAGAGCGGC TGACTGAGCGCCTCTGTCCCCCTGGGATTCCCACTCCCGGCTCTGGACTTCCACCACCACGAAAGGTTCT GATCCTGGGCTCAGGGGGCCTCTCCATTGGCCAAGCTGGAGAATTTGACTACTCGGGCTCTCAGGCAATT AAGGCCCTGAAGGAGGAAAACATCCAGACGTTGCTGATCAACCCCAATATTGCCACAGTGCAGACCTCCC AGGGGCTGGCCGACAAGGTCTATTTTCTTCCCATAACACCTCATTATGTAACCCAGGTGATACGTAATGA ACGCCCCGATGGTGTGTTACTGACTTTTGGGGGCCAGACTGCTCTGAACTGTGGTGTGGAGCTGACCAAG GCCGGGGTGCTGGCTCGGTATGGGGTCCGGGTCCTGGGCACACCAGTGGAGACCATTGAGCTGACCGAGG ATCGACGGGCCTTTGCTGCCAGAATGGCAGAGATCGGAGAGCATGTGGCCCCGAGCGAGGCAGCAAATTC TCTTGAACAGGCCCAGGCAGCCGCTGAACGGCTGGGGTACCCTGTGCTAGTGCGTGCAGCCTTTGCCCTG GGTGGCCTGGGCTCTGGCTTTGCCTCTAACAGGGAGGAGCTCTCTGCTCTCGTGGCCCCAGCTTTTGCCC ATACCAGCCAAGTGCTAGTAGACAAGTCTCTGAAGGGATGGAAGGAGATTGAGTACGAGGTGGTGAGAGA CGCCTATGGCAACTGTGTCACGGTGTGTAACATGGAGAACTTGGACCCACTGGGCATCCACACTGGTGAG TCCATAGTGGTGGCCCCTAGCCAGACACTGAATGACAGGGAGTATCAGCTCCTGAGGCAGACAGCTATCA AGGTGACCCAGCACCTGGGAATTGTTGGGGAGTGCAATGTGCAGTATGCCTTGAACCCTGAGTCTGAGCA GTATTACATCATTGAAGTGAATGCCAGGCTCTCTCGCAGCTCTGCCCTGGCCAGTAAGGCCACAGGTTAT CCACTGGCTTATGTGGCAGCCAAGCTAGCATTGGGCATCCCTTTGCCTGAGCTCAGGAACTCTGTGACAG GGGGTACAGCAGCCTTTGAACCCAGCGTGGATTATTGTGTGGTGAAGATTCCTCGATGGGACCTTAGCAA GTTCCTGCGAGTCAGCACAAAGATTGGGAGCTGCATGAAGAGCGTTGGTGAAGTCATGGGCATTGGGCGT TCATTTGAGGAGGCCTTCCAGAAGGCCCTGCGCATGGTGGATGAGAACTGTGTGGGCTTTGATCACACAG TGAAACCAGTCAGCGATATGGAGTTGGAGACTCCAACAGATAAGCGGATTTTTGTGGTGGCAGCTGCTTT GTGGGCTGGTTATTCAGTGGACCGCCTGTATGAGCTCACACGCATCGACCGCTGGTTCCTGCACCGAATG AAGCGTATCATCGCACATGCCCAGCTGCTAGAACAACACCGTGGACAGCCTTTGCCGCCAGACCTGCTGC AACAGGCCAAGTGTCTTGGCTTCTCAGACAAACAGATTGCCCTTGCAGTTCTGAGCACAGAGCTGGCTGT TCGCAAGCTGCGTCAGGAACTGGGGATCTGTCCAGCAGTGAAACAGATTGACACAGTTGCAGCTGAGTGG CCAGCCCAGACAAATTACCTATACCTAACGTATTGGGGCACCACCCATGACCTCACCTTTCGAACACCTC ATGTCCTAGTCCTTGGCTCTGGCGTCTACCGTATTGGCTCTAGCGTTGAATTTGACTGGTGTGCTGTAGG CTGCATCCAGCAGCTCCGAAAGATGGGATATAAGACCATCATGGTGAACTATAACCCAGAGACAGTCAGC ACCGACTATGACATGTGTGATCGACTCTACTTTGATGAGATCTCTTTTGAGGTGGTGATGGACATCTATG AGCTCGAGAACCCTGAAGGTGTGATCCTATCCATGGGTGGACAGCTGCCCAACAACATGGCCATGGCGTT GCATCGGCAGCAGTGCCGGGTGCTGGGCACCTCCCCTGAAGCCATTGACTCGGCTGAGAACCGTTTCAAG TTTTCCCGGCTCCTTGACACCATTGGTATCAGCCAGCCTCAGTGGAGGGAGCTCAGTGACCTCGAGTCTG CTCGCCAATTCTGCCAGACCGTGGGGTACCCCTGTGTGGTGCGCCCCTCCTATGTGCTGAGCGGTGCTGC TATGAATGTGGCCTACACGGATGGAGACCTGGAGCGCTTCCTGAGCAGCGCAGCAGCCGTCTCCAAAGAG CATCCCGTGGTCATCTCCAAGTTCATCCAGGAGGCTAAGGAGATTGACGTGGATGCCGTGGCCTCTGATG GTGTGGTGGCAGCCATCGCCATCTCTGAGCATGTGGAGAATGCAGGTGTGCATTCAGGTGATGCGACGCT GGTGACCCCCCCACAAGATATCACTGCCAAAACCCTGGAGCGGATCAAAGCCATTGTGCATGCTGTGGGC CAGGAGCTACAGGTCACAGGACCCTTCAATCTGCAGCTCATTGCCAAGGATGACCAGCTGAAAGTTATTG AATGCAACGTACGTGTCTCTCGCTCCTTCCCCTTCGTTTCCAAGACACTGGGTGTGGACCTAGTAGCCTT GGCCACGCGGGTCATCATGGGGGAAGAAGTGGAACCTGTGGGGCTAATGACTGGTTCTGGAGTCGTGGGA GTAAAGGTGCCTCAGTTCTCCTTCTCCCGCTTGGCGGGTGCTGACGTGGTGTTGGGTGTGGAAATGACCA GTACTGGGGAGGTGGCCGGCTTTGGGGAGAGCCGCTGTGAGGCATACCTCAAGGCCATGCTAAGCACTGG CTTTAAGATCCCCAAGAAGAATATCCTGCTGACCATTGGCAGCTATAAGAACAAAAGCGAGCTGCTCCCA ACTGTGCGGCTACTGGAGAGCCTGGGCTACAGCCTCTATGCCAGTCTCGGCACAGCTGACTTCTACACTG AGCATGGCGTCAAGGTAACAGCTGTGGACTGGCACTTTGAGGAGGCTGTGGATGGTGAGTGCCCACCACA GCGGAGCATCCTGGAGCAGCTAGCTGAGAAAAACTTTGAGCTGGTGATTAACCTGTCAATGCGTGGAGCT GGGGGCCGGCGTCTCTCTTCCTTTGTCACCAAGGGCTACCGCACCCGACGCTTGGCCGCTGACTTCTCCG TGCCCCTAATCATCGATATCAAGTGCACCAAACTCTTTGTGGAGGCCCTAGGCCAGATCGGGCCAGCCCC TCCTTTGAAGGTGCATGTTGACTGTATGACCTCCCAAAAGCTTGTGCGACTGCCGGGATTGATTGATGTC CATGTGCACCTGCGGGAACCAGGTGGGACACATAAGGAGGACTTTGCTTCAGGCACAGCCGCTGCCCTGG CTGGGGGTATCACCATGGTGTGTGCCATGCCTAATACCCGGCCCCCCATCATTGACGCCCCTGCTCTGGC CCTGGCCCAGAAGCTGGCAGAGGCTGGCGCCCGGTGCGACTTTGCGCTATTCCTTGGGGCCTCGTCTGAA AATGCAGGAACCTTGGGCACCGTGGCCGGGTCTGCAGCCGGGCTGAAGCTTTACCTCAATGAGACCTTCT CTGAGCTGCGGCTGGACAGCGTGGTCCAGTGGATGGAGCATTTCGAGACATGGCCCTCCCACCTCCCCAT TGTGGCTCACGCAGAGCAGCAAACCGTGGCTGCTGTCCTCATGGTGGCTCAGCTCACTCAGCGCTCAGTG CACATATGTCACGTGGCACGGAAGGAGGAGATCCTGCTAATTAAAGCTGCAAAGGCACGGGGCTTGCCAG TGACCTGCGAGGTGGCTCCCCACCACCTGTTCCTAAGCCATGATGACCTGGAGCGCCTGGGGCCTGGGAA GGGGGAGGTCCGGCCTGAGCTTGGCTCCCGCCAGGATGTGGAAGCCCTGTGGGAGAACATGGCTGTCATC GACTGCTTTGCCTCAGACCATGCTCCCCATACCTTGGAGGAGAAGTGTGGGTCCAGGCCCCCACCTGGGT TCCCAGGGTTAGAGACCATGCTGCCACTACTCCTGACGGCTGTAAGCGAGGGCCGGCTCAGCCTGGACGA CCTGCTGCAGCGATTGCACCACAATCCTCGGCGCATCTTTCACCTGCCCCCGCAGGAGGACACCTATGTG GAGGTGGATCTGGAGCATGAGTGGACAATTCCCAGCCACATGCCCTTCTCCAAGGCCCACTGGACACCTT TTGAAGGGCAGAAAGTGAAGGGCACCGTCCGCCGTGTGGTCCTGCGAGGGGAGGTTGCCTATATCGATGG GCAGGTTCTGGTACCCCCGGGCTATGGACAGGATGTACGGAAGTGGCCACAGGGGGCTGTTCCTCAGCTC CCACCCTCAGCCCCTGCCACTAGTGAGATGACCACGACACCTGAAAGACCCCGCCGTGGCATCCCAGGGC TTCCTGATGGCCGCTTCCATCTGCCGCCCCGAATCCATCGAGCCTCCGACCCAGGTTTGCCAGCTGAGGA GCCAAAGGAGAAGTCCTCTCGGAAGGTAGCCGAGCCAGAGCTGATGGGAACCCCTGATGGCACCTGCTAC CCTCCACCACCAGTACCGAGACAGGCATCTCCCCAGAACCTGGGGACCCCTGGCTTGCTGCACCCCCAGA CCTCACCCCTGCTGCACTCATTAGTGGGCCAACATATCCTGTCCGTCCAGCAGTTCACCAAGGATCAGAT GTCTCACCTGTTCAATGTGGCACACACACTGCGTATGATGGTGCAGAAGGAGCGGAGCCTCGACATCCTG AAGGGGAAGGTCATGGCCTCCATGTTCTATGAAGTGAGCACACGGACCAGCAGCTCCTTTGCAGCAGCCA TGGCCCGGCTGGGAGGTGCTGTGCTCAGCTTCTCGGAAGCCACATCGTCCGTCCAGAAGGGCGAATCCCT GGCTGACTCCGTGCAGACCATGAGCTGCTATGCCGACGTCGTCGTGCTCCGGCACCCCCAGCCTGGAGCA GTGGAGCTGGCCGCCAAGCACTGCCGGAGGCCAGTGATCAATGCTGGGGATGGGGTCGGAGAGCACCCCA CCCAGGCCCTGCTGGACATCTTCACCATCCGTGAGGAGCTGGGAACTGTCAATGGCATGACGATCACGAT GGTGGGTGACCTGAAGCACGGACGCACAGTACATTCCCTGGCCTGCCTGCTCACCCAGTATCGTGTCAGC CTGCGCTACGTGGCACCTCCCAGCCTGCGCATGCCACCCACTGTGCGGGCCTTCGTGGCCTCCCGCGGCA CCAAGCAGGAGGAATTCGAGAGCATTGAGGAGGCGCTGCCTGACACTGATGTGCTCTACATGACTCGAAT CCAGAAGGAACGATTTGGCTCTACCCAGGAGTACGAAGCTTGCTTTGGTCAGTTCATCCTCACTCCCCAC ATCATGACCCGGGCCAAGAAGAAGATGGTGGTGATGCACCCGATGCCCCGTGTCAACGAGATAAGCGTGG AAGTGGACTCGGATCCCCGCGCAGCCTACTTCCGCCAGGCTGAGAACGGCATGTACATCCGCATGGCTCT GTTAGCCACCGTGCTGGGCCGTTTCTAG Download Select all
CCDS ID	CCDS1742.1

Protein Information

Protein ID	NP_004332.2
Protein Name	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
Molecular Wt. (Da)	242854
Protein Sequence	>lcl\|NM_004341.4_prot_NP_004332.2_1 [gene=CAD] [protein=CAD protein isoform 1] [protein_id=NP_004332.2] [location=163..6840] MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNYGIPPDEMDEF GLCKWFESSGIHVAALVVGECCPTPSHWSATRTLHEWLQQHGIPGLQGVDTRELTKKLREQGSLLGKLVQ NGTEPSSLPFLDPNARPLVPEVSIKTPRVFNTGGAPRILALDCGLKYNQIRCLCQRGAEVTVVPWDHALD SQEYEGLFLSNGPGDPASYPSVVSTLSRVLSEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPC LLVGSGRCFLTSQNHGFAVETDSLPADWAPLFTNANDGSNEGIVHNSLPFFSVQFHPEHQAGPSDMELLF DIFLETVKEATAGNPGGQTVRERLTERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQTALNCGVELTK AGVLARYGVRVLGTPVETIELTEDRRAFAARMAEIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFAL GGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGE SIVVAPSQTLNDREYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGY PLAYVAAKLALGIPLPELRNSVTGGTAAFEPSVDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGR SFEEAFQKALRMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRM KRIIAHAQLLEQHRGQPLPPDLLQQAKCLGFSDKQIALAVLSTELAVRKLRQELGICPAVKQIDTVAAEW PAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQQLRKMGYKTIMVNYNPETVS TDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFK FSRLLDTIGISQPQWRELSDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKE HPVVISKFIQEAKEIDVDAVASDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVG QELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTGSGVVG VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIGSYKNKSELLP TVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSILEQLAEKNFELVINLSMRGA GGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEALGQIGPAPPLKVHVDCMTSQKLVRLPGLIDV HVHLREPGGTHKEDFASGTAAALAGGITMVCAMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGASSE NAGTLGTVAGSAAGLKLYLNETFSELRLDSVVQWMEHFETWPSHLPIVAHAEQQTVAAVLMVAQLTQRSV HICHVARKEEILLIKAAKARGLPVTCEVAPHHLFLSHDDLERLGPGKGEVRPELGSRQDVEALWENMAVI DCFASDHAPHTLEEKCGSRPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIFHLPPQEDTYV EVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQGAVPQL PPSAPATSEMTTTPERPRRGIPGLPDGRFHLPPRIHRASDPGLPAEEPKEKSSRKVAEPELMGTPDGTCY PPPPVPRQASPQNLGTPGLLHPQTSPLLHSLVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDIL KGKVMASMFYEVSTRTSSSFAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGA VELAAKHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS LRYVAPPSLRMPPTVRAFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSTQEYEACFGQFILTPH IMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLATVLGRF Download Select all
Length	2225
Uniprot ID	P15941
Ensembl Protein ID	ENSP00000338983

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
T	Phosphorylation	456
D	Proteolytic Cleavage	1143
D	Proteolytic Cleavage	1371
S	Phosphorylation	1406
S	Phosphorylation	1859
T	Phosphorylation	1037
S	Dephosphorylation	1859
S	Dephosphorylation	1406
S	Phosphorylation	1859;-
S	Phosphorylation	1823;-
S	Phosphorylation	1920;-
T	Phosphorylation	1884
S	Phosphorylation	1038
K	Acetylation	747
K	Acetylation	1411
T	Phosphorylation	375
S	Phosphorylation	10
T	Phosphorylation	172
S	Phosphorylation	1407
S	Phosphorylation	1900
T	Phosphorylation	1906
S	Phosphorylation	1073

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

No matching records from HPRD source could be found.

Pathway Information

Pathway Name	Pathway ID
Alanine, aspartate and glutamate metabolism	hsa00250
Metabolic pathways	hsa01100
Pyrimidine metabolism	hsa00240

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
cd01316	1460-1806	CAD_DHOase
cl00281	1460-1806	metallo-dependent_hydrolases superfamily
cd01744	178-354	GATase1_CPSase
cl00020	178-354	GAT_1 superfamily
cd01423	1313-1438	MGS_CPS_I_III
cl00245	1313-1438	MGS-like superfamily
cd01302	1461-1786	Cyclic_amidohydrolases
pfam02786	514-718	CPSase_L_D2
cl17255	514-718	ATP-grasp_4 superfamily
cd01318	1464-1790	DHOase_IIb
smart01097	2-138	CPSase_sm_chain
cl03056	2-138	CPSase_sm_chain superfamily
cd01317	1453-1786	DHOase_IIa
pfam00988	2-139	CPSase_sm_chain
cd01315	1461-1803	L-HYD_ALN
pfam02729	1924-2066	OTCace_N
cl03681	1924-2066	OTCace_N superfamily
smart01096	799-921	CPSase_L_D3
cl19748	799-921	CPSase_L_D3 superfamily
pfam02787	801-921	CPSase_L_D3
cd01314	1439-1806	D-HYD
pfam00185	2071-2221	OTCace
cl21454	2071-2221	NADB_Rossmann superfamily
cd01743	187-338	GATase1_Anthranilate_Synthase
cd01292	1467-1739	metallo-dependent_hydrolases
pfam02786	1048-1245	CPSase_L_D2
cl17255	1048-1245	ATP-grasp_4 superfamily
pfam00289	393-508	CPSase_L_chain
cl02837	393-508	CPSase_L_chain superfamily
pfam00289	935-1041	CPSase_L_chain
cl02837	935-1041	CPSase_L_chain superfamily
pfam02142	1327-1427	MGS
pfam13535	1047-1223	ATP-grasp_4
TIGR00566	187-338	trpG_papA
cd01294	1464-1778	DHOase
PRK07765	177-338	PRK07765
PRK06774	187-355	PRK06774
PRK05670	187-338	PRK05670
smart00851	1327-1427	MGS
cd01741	190-340	GATase1_1
PRK06895	209-338	PRK06895
pfam02222	1055-1209	ATP-grasp
cd01742	178-338	GATase1_GMP_Synthase
pfam01979	1464-1740	Amidohydro_1
cd01424	1314-1427	MGS_CPS_II
COG0418	1458-1784	PyrC
PRK07649	187-362	PRK07649
pfam13535	514-691	ATP-grasp_4
pfam13594	1437-1500	Amidohydro_5
CHL00101	187-338	trpG
pfam07478	534-684	Dala_Dala_lig_C
PLN02335	216-338	PLN02335
TIGR00856	1462-1784	pyrC_dimer
cd01745	247-353	GATase1_2
cd01653	190-263	GATase1
pfam08443	1045-1234	RimK
cd03128	190-258	GAT_1
PRK08007	187-338	PRK08007
cd01747	247-341	GATase1_Glutamyl_Hydrolase
pfam07478	1054-1186	Dala_Dala_lig_C
pfam02222	529-663	ATP-grasp
cd01421	1313-1395	IMPCH
pfam01071	1051-1218	GARS_A
PRK05451	1469-1774	PRK05451
PRK07053	246-269	PRK07053
PRK09065	247-338	PRK09065
TIGR01369	391-1440	CPSaseII_lrg
PRK12564	1-355	PRK12564
PRK00856	1920-2224	pyrB
TIGR00857	1461-1796	pyrC_multi
PRK05294	394-1440	carB
PRK12815	394-1448	carB
PLN02735	394-1440	PLN02735
COG0458	399-784	CarB
COG0505	1-360	CarA
TIGR01368	2-359	CPSaseIIsmall
PLN02527	1924-2223	PLN02527
PRK12838	4-360	PRK12838
COG0540	1923-2223	PyrB
TIGR00670	1925-2223	asp_carb_tr
COG0044	1461-1804	AllB
PRK08192	1923-2223	PRK08192
PRK11891	1924-2223	PRK11891
PRK09357	1461-1796	pyrC
CHL00197	2-358	carA
PLN02771	2-350	PLN02771
PRK04250	1464-1803	PRK04250
PRK02382	1464-1810	PRK02382
PRK07575	1442-1799	PRK07575
PRK09060	1429-1810	PRK09060
pfam00117	179-355	GATase
COG0458	938-1305	CarB
PRK09236	1464-1799	PRK09236
PRK06189	1464-1811	PRK06189
COG0078	1919-2223	ArgF
TIGR03178	1461-1803	allantoinase
PRK00369	1464-1804	pyrC
PRK01211	1464-1811	PRK01211
PRK13814	1925-2224	pyrB
TIGR00658	1925-2223	orni_carb_tr
PRK00779	1920-2222	PRK00779
TIGR02033	1442-1811	D-hydantoinase
PRK07369	1442-1783	PRK07369
PRK08323	1460-1817	PRK08323
PRK13404	1460-1846	PRK13404
PRK13376	1920-2223	pyrB
PRK07627	1443-1794	PRK07627
PLN02342	1882-2223	PLN02342
PLN02795	1462-1797	PLN02795
PRK09059	1446-1794	PRK09059
PRK08044	1454-1794	PRK08044
PRK02255	1925-2219	PRK02255
TIGR04384	1925-2219	putr_carbamoyl
PRK14805	1924-2223	PRK14805
PRK02102	1921-2223	PRK02102
PRK04284	1920-2224	PRK04284
COG0512	187-338	PabA
PRK12767	395-717	PRK12767
PRK12767	1026-1249	PRK12767
PRK12562	1918-2224	PRK12562
PRK03515	1924-2222	PRK03515
pfam13147	1464-1744	Amidohydro_4
PRK08462	493-717	PRK08462
PRK01713	1920-2222	PRK01713
COG0439	1029-1246	AccC
PRK04523	1924-2224	PRK04523
PRK14804	1924-2222	PRK14804
PRK06111	498-785	PRK06111
PRK07178	491-716	PRK07178
TIGR01235	421-727	pyruv_carbox
COG0439	495-716	AccC
pfam15632	498-717	ATPgrasp_Ter
PRK13566	172-338	PRK13566
TIGR00888	178-338	guaA_Nterm
COG1181	489-686	DdlA
COG1038	498-687	PycA
TIGR00514	491-716	accC
TIGR01823	178-371	PabB-fungal
COG4770	491-687	PccA
PRK08654	498-716	PRK08654
PRK08857	187-338	PRK08857
PRK12833	498-716	PRK12833
COG0518	238-342	GuaA1
PRK12999	498-687	PRK12999
PRK08417	1464-1794	PRK08417
PRK14607	247-338	PRK14607
pfam15632	1024-1255	ATPgrasp_Ter
PLN02942	1446-1813	PLN02942
TIGR01815	195-338	TrpE-clade3
PRK07200	1933-2143	PRK07200
PRK08463	498-712	PRK08463
TIGR03316	1933-2143	ygeW
PRK05586	502-715	PRK05586
PRK00758	247-338	PRK00758
TIGR02712	537-730	urea_carbox
PRK08591	507-687	PRK08591
TIGR01142	997-1272	purT
TIGR01205	529-684	D_ala_D_alaTIGR
PRK06849	1032-1219	PRK06849
COG2232	1032-1251	COG2232
PRK02186	503-791	PRK02186
COG0026	1038-1214	PurK
pfam07722	247-338	Peptidase_C26
COG0189	991-1217	RimK
COG1181	1053-1216	DdlA
COG0027	1047-1218	PurT
PRK00074	177-338	guaA
TIGR01235	1033-1244	pyruv_carbox
TIGR01205	1053-1198	D_ala_D_alaTIGR
COG0026	507-663	PurK
TIGR00768	1038-1242	rimK_fam
TIGR01142	395-731	purT
PRK01966	522-601	ddl
TIGR00514	1068-1247	accC
PRK01372	529-684	ddl
COG0027	391-604	PurT
pfam03251	1834-1921	Tymo_45kd_70kd
PRK14570	1079-1143	PRK14570
PRK08654	1035-1141	PRK08654
TIGR01161	1038-1222	purK
PRK02186	1036-1275	PRK02186
PRK06019	1038-1212	PRK06019
PLN02889	214-338	PLN02889
PRK06019	507-663	PRK06019
PRK12833	1067-1245	PRK12833
PLN02948	1059-1218	PLN02948
PRK08462	1068-1249	PRK08462
TIGR00877	1053-1218	purD
COG0138	1311-1372	PurH
PRK14572	492-596	PRK14572

Ontology Information

HPRD ID	11828
Molecular Class	Enzyme: Ligase
Molecular Function	Molecular function unknown (GO:0005554)
Biological Process	Biological_process unknown (GO:0000004)

SNP Information

View SNP Geneview Report

Drug Information

Uniprot ID DrugBank ID Name Type
P27708 DB00130 L-Glutamine SmallMoleculeDrug
P27708 DB00128 L-Aspartic Acid SmallMoleculeDrug

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

Uniprot ID	DrugBank ID	Name	Type
P27708	DB00130	L-Glutamine	SmallMoleculeDrug
P27708	DB00128	L-Aspartic Acid	SmallMoleculeDrug

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO