CoReCG

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
20812987	2010	Cell line : - Source : Nanfang Hospital tumour tissue bank. Sample Type : CRC tumor and Normal tissue No. of Sample : 150 Stage : -	2D-Gel electrophoresis, and mass spectrometry,Western blotting, Immunohistochemistry	Up-regulation	-	This gene differentially expressed in between normal colorectal tissue and colorectal cancer tissue experiment done by 2-D Gel eclectrophotesis

Gene Details

Chromosome: 3; NC_000003.11 (46411633..46417697)
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Gene Type	protein coding
Gene Family	GPCR / Class A : Chemokine receptors : C-C motif, CD molecules
Description	This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	3
Location	3p21.31
Start	46370142
End	46376206
Strand	+
Gene Sequence	>gi\|568815595:46370142-46376206 Homo sapiens chromosome 3, GRCh38.p2 Primary Assembly CTTCAGATAGATTATATCTGGAGTGAAGAATCCTGCCACCTATGTATCTGGCATAGTGTGAGTCCTCATA AATGCTTACTGGTTTGAAGGGCAACAAAATAGTGAACAGAGTGAAAATCCCCACTAAGATCCTGGGTCCA GAAAAAGATGGGAAACCTGTTTAGCTCACCCGTGAGCCCATAGTTAAAACTCTTTAGACAACAGGTTGTT TCCGTTTACAGAGAACAATAATATTGGGTGGTGAGCATCTGTGTGGGGGTTGGGGTGGGATAGGGGATAC GGGGAGAGTGGAGAAAAAGGGGACACAGGGTTAATGTGAAGTCCAGGATCCCCCTCTACATTTAAAGTTG GTTTAAGTTGGCTTTAATTAATAGCAACTCTTAAGATAATCAGAATTTTCTTAACCTTTTAGCCTTACTG TTGAAAAGCCCTGTGATCTTGTACAAATCATTTGCTTCTTGGATAGTAATTTCTTTTACTAAAATGTGGG CTTTTGACTAGATGAATGTAAATGTTCTTCTAGCTCTGATATCCTTTATTCTTTATATTTTCTAACAGAT TCTGTGTAGTGGGATGAGCAGAGAACAAAAACAAAATAATCCAGTGAGAAAAGCCCGTAAATAAACCTTC AGACCAGAGATCTATTCTCTAGCTTATTTTAAGCTCAACTTAAAAAGAAGAACTGTTCTCTGATTCTTTT CGCCTTCAATACACTTAATGATTTAACTCCACCCTCCTTCAAAAGAAACAGCATTTCCTACTTTTATACT GTCTATATGATTGATTTGCACAGCTCATCTGGCCAGAAGAGCTGAGACATCCGTTCCCCTACAAGAAACT CTCCCCGGTAAGTAACCTCTCAGCTGCTTGGCCTGTTAGTTAGCTTCTGAGATGAGTAAAAGACTTTACA GGAAACCCATAGAAGACATTTGGCAAACACCAAGTGCTCATACAATTATCTTAAAATATAATCTTTAAGA TAAGGAAAGGGTCACAGTTTGGAATGAGTTTCAGACGGTTATAACATCAAAGATACAAAACATGATTGTG AGTGAAAGACTTTAAAGGGAGCAATAGTATTTTAATAACTAACAATCCTTACCTCTCAAAAGAAAGATTT GCAGAGAGATGAGTCTTAGCTGAAATCTTGAAATCTTATCTTCTGCTAAGGAGAACTAAACCCTCTCCAG TGAGATGCCTTCTGAATATGTGCCCACAAGAAGTTGTGTCTAAGTCTGGTTCTCTTTTTTCTTTTTCCTC CAGACAAGAGGGAAGCCTAAAAATGGTCAAAATTAATATTAAATTACAAACGCCAAATAAAATTTTCCTC TAATATATCAGTTTCATGGCACAGTTAGTATATAATTCTTTATGGTTCAAAATTAAAAATGAGCTTTTCT AGGGGCTTCTCTCAGCTGCCTAGTCTAAGGTGCAGGGAGTTTGAGACTCACAGGGTTTAATAAGAGAAAA TTCTCAGCTAGAGCAGCTGAACTTAAATAGACTAGGCAAGACAGCTGGTTATAAGACTAAACTACCCAGA ATGCATGACATTCATCTGTGGTGGCAGACGAAACATTTTTTATTATATTATTTCTTGGGTATGTATGACA ACTCTTAATTGTGGCAACTCAGAAACTACAAACACAAACTTCACAGAAAATGTGAGGATTTTACAATTGG CTGTTGTCATCTATGACCTTCCCTGGGACTTGGGCACCCGGCCATTTCACTCTGACTACATCATGTCACC AAACATCTGATGGTCTTGCCTTTTAATTCTCTTTTCGAGGACTGAGAGGGAGGGTAGCATGGTAGTTAAG AGTGCAGGCTTCCCGCATTCAAAATCGGTTGCTTACTAGCTGTGTGGCTTTGAGCAAGTTACTCACCCTC TCTGTGCTTCAAGGTCCTTGTCTGCAAAATGTGAAAAATATTTCCTGCCTCATAAGGTTGCCCTAAGGAT TAAATGAATGAATGGGTATGATGCTTAGAACAGTGATTGGCATCCAGTATGTGCCCTCGAGGCCTCTTAA TTATTACTGGCTTGCTCATAGTGCATGTTCTTTGTGGGCTAACTCTAGCGTCAATAAAAATGTTAAGACT GAGTTGCAGCCGGGCATGGTGGCTCATGCCTGTAATCCCAGCATTCTAGGAGGCTGAGGCAGGAGGATCG CTTGAGCCCAGGAGTTCGAGACCAGCCTGGGCAACATAGTGTGATCTTGTATCTATAAAAATAAACAAAA TTAGCTTGGTGTGGTGGCGCCTGTAGTCCCCAGCCACTTGGAGGGGTGAGGTGAGAGGATTGCTTGAGCC CGGGATGGTCCAGGCTGCAGTGAGCCATGATCGTGCCACTGCACTCCAGCCTGGGCGACAGAGTGAGACC CTGTCTCACAACAACAACAACAACAACAAAAAGGCTGAGCTGCACCATGCTTGACCCAGTTTCTTAAAAT TGTTGTCAAAGCTTCATTCACTCCATGGTGCTATAGAGCACAAGATTTTATTTGGTGAGATGGTGCTTTC ATGAATTCCCCCAACAGAGCCAAGCTCTCCATCTAGTGGACAGGGAAGCTAGCAGCAAACCTTCCCTTCA CTACAAAACTTCATTGCTTGGCCAAAAAGAGAGTTAATTCAATGTAGACATCTATGTAGGCAATTAAAAA CCTATTGATGTATAAAACAGTTTGCATTCATGGAGGGCAACTAAATACATTCTAGGACTTTATAAAAGAT CACTTTTTATTTATGCACAGGGTGGAACAAGATGGATTATCAAGTGTCAAGTCCAATCTATGACATCAAT TATTATACATCGGAGCCCTGCCAAAAAATCAATGTGAAGCAAATCGCAGCCCGCCTCCTGCCTCCGCTCT ACTCACTGGTGTTCATCTTTGGTTTTGTGGGCAACATGCTGGTCATCCTCATCCTGATAAACTGCAAAAG GCTGAAGAGCATGACTGACATCTACCTGCTCAACCTGGCCATCTCTGACCTGTTTTTCCTTCTTACTGTC CCCTTCTGGGCTCACTATGCTGCCGCCCAGTGGGACTTTGGAAATACAATGTGTCAACTCTTGACAGGGC TCTATTTTATAGGCTTCTTCTCTGGAATCTTCTTCATCATCCTCCTGACAATCGATAGGTACCTGGCTGT CGTCCATGCTGTGTTTGCTTTAAAAGCCAGGACGGTCACCTTTGGGGTGGTGACAAGTGTGATCACTTGG GTGGTGGCTGTGTTTGCGTCTCTCCCAGGAATCATCTTTACCAGATCTCAAAAAGAAGGTCTTCATTACA CCTGCAGCTCTCATTTTCCATACAGTCAGTATCAATTCTGGAAGAATTTCCAGACATTAAAGATAGTCAT CTTGGGGCTGGTCCTGCCGCTGCTTGTCATGGTCATCTGCTACTCGGGAATCCTAAAAACTCTGCTTCGG TGTCGAAATGAGAAGAAGAGGCACAGGGCTGTGAGGCTTATCTTCACCATCATGATTGTTTATTTTCTCT TCTGGGCTCCCTACAACATTGTCCTTCTCCTGAACACCTTCCAGGAATTCTTTGGCCTGAATAATTGCAG TAGCTCTAACAGGTTGGACCAAGCTATGCAGGTGACAGAGACTCTTGGGATGACGCACTGCTGCATCAAC CCCATCATCTATGCCTTTGTCGGGGAGAAGTTCAGAAACTACCTCTTAGTCTTCTTCCAAAAGCACATTG CCAAACGCTTCTGCAAATGCTGTTCTATTTTCCAGCAAGAGGCTCCCGAGCGAGCAAGCTCAGTTTACAC CCGATCCACTGGGGAGCAGGAAATATCTGTGGGCTTGTGACACGGACTCAAGTGGGCTGGTGACCCAGTC AGAGTTGTGCACATGGCTTAGTTTTCATACACAGCCTGGGCTGGGGGTGGGGTGGGAGAGGTCTTTTTTA AAAGGAAGTTACTGTTATAGAGGGTCTAAGATTCATCCATTTATTTGGCATCTGTTTAAAGTAGATTAGA TCTTTTAAGCCCATCAATTATAGAAAGCCAAATCAAAATATGTTGATGAAAAATAGCAACCTTTTTATCT CCCCTTCACATGCATCAAGTTATTGACAAACTCTCCCTTCACTCCGAAAGTTCCTTATGTATATTTAAAA GAAAGCCTCAGAGAATTGCTGATTCTTGAGTTTAGTGATCTGAACAGAAATACCAAAATTATTTCAGAAA TGTACAACTTTTTACCTAGTACAAGGCAACATATAGGTTGTAAATGTGTTTAAAACAGGTCTTTGTCTTG CTATGGGGAGAAAAGACATGAATATGATTAGTAAAGAAATGACACTTTTCATGTGTGATTTCCCCTCCAA GGTATGGTTAATAAGTTTCACTGACTTAGAACCAGGCGAGAGACTTGTGGCCTGGGAGAGCTGGGGAAGC TTCTTAAATGAGAAGGAATTTGAGTTGGATCATCTATTGCTGGCAAAGACAGAAGCCTCACTGCAAGCAC TGCATGGGCAAGCTTGGCTGTAGAAGGAGACAGAGCTGGTTGGGAAGACATGGGGAGGAAGGACAAGGCT AGATCATGAAGAACCTTGACGGCATTGCTCCGTCTAAGTCATGAGCTGAGCAGGGAGATCCTGGTTGGTG TTGCAGAAGGTTTACTCTGTGGCCAAAGGAGGGTCAGGAAGGATGAGCATTTAGGGCAAGGAGACCACCA ACAGCCCTCAGGTCAGGGTGAGGATGGCCTCTGCTAAGCTCAAGGCGTGAGGATGGGAAGGAGGGAGGTA TTCGTAAGGATGGGAAGGAGGGAGGTATTCGTGCAGCATATGAGGATGCAGAGTCAGCAGAACTGGGGTG GATTTGGGTTGGAAGTGAGGGTCAGAGAGGAGTCAGAGAGAATCCCTAGTCTTCAAGCAGATTGGAGAAA CCCTTGAAAAGACATCAAGCACAGAAGGAGGAGGAGGAGGTTTAGGTCAAGAAGAAGATGGATTGGTGTA AAAGGATGGGTCTGGTTTGCAGAGCTTGAACACAGTCTCACCCAGACTCCAGGCTGTCTTTCACTGAATG CTTCTGACTTCATAGATTTCCTTCCCATCCCAGCTGAAATACTGAGGGGTCTCCAGGAGGAGACTAGATT TATGAATACACGAGGTATGAGGTCTAGGAACATACTTCAGCTCACACATGAGATCTAGGTGAGGATTGAT TACCTAGTAGTCATTTCATGGGTTGTTGGGAGGATTCTATGAGGCAACCACAGGCAGCATTTAGCACATA CTACACATTCAATAAGCATCAAACTCTTAGTTACTCATTCAGGGATAGCACTGAGCAAAGCATTGAGCAA AGGGGTCCCATAGAGGTGAGGGAAGCCTGAAAAACTAAGATGCTGCCTGCCCAGTGCACACAAGTGTAGG TATCATTTTCTGCATTTAACCGTCAATAGGCAAAGGGGGGAAGGGACATATTCATTTGGAAATAAGCTGC CTTGAGCCTTAAAACCCACAAAAGTACAATTTACCAGCCTCCGTATTTCAGACTGAATGGGGGTGGGGGG GGCGCCTTAGGTACTTATTCCAGATGCCTTCTCCAGACAAACCAGAAGCAACAGAAAAAATCGTCTCTCC CTCCCTTTGAAATGAATATACCCCTTAGTGTTTGGGTATATTCATTTCAAAGGGAGAGAGAGAGGTTTTT TTCTGTTCTGTCTCATATGATTGTGCACATACTTGAGACTGTTTTGAATTTGGGGGATGGCTAAAACCAT CATAGTACAGGTAAGGTGAGGGAATAGTAAGTGGTGAGAACTACTCAGGGAATGAAGGTGTCAGAATAAT AAGAGGTGCTACTGACTTTCTCAGCCTCTGAATATGAACGGTGAGCATTGTGGCTGTCAGCAGGAAGCAA CGAAGGGAAATGTCTTTCCTTTTGCTCTTAAGTTGTGGAGAGTGCAACAGTAGCATAGGACCCTACCCTC TGGGCCAAGTCAAAGACATTCTGACATCTTAGTATTTGCATATTCTTATGTATGTGAAAGTTACAAATTG CTTGAAAGAAAATATGCATCTAATAAAAAACACCTTCTAAAATAA Download Select all
Length	6065
OMIM ID	601373
HGNC ID	HGNC:1606
Unigene ID	Hs.450802
Ensembl ID	ENSG00000160791
PharmGKB ID	-

mRNA Information

mRNA ID	NM_000579.3
Exon	join(1..57,559..847,2751..6065)
mRNA Sequence	>1234 CTTCAGATAGATTATATCTGGAGTGAAGAATCCTGCCACCTATGTATCTGGCATAGTATTCTGT GTAGTGGGATGAGCAGAGAACAAAAACAAAATAATCCAGTGAGAAAAGCCCGTAAATAAACCTT CAGACCAGAGATCTATTCTCTAGCTTATTTTAAGCTCAACTTAAAAAGAAGAACTGTTCTCTGA TTCTTTTCGCCTTCAATACACTTAATGATTTAACTCCACCCTCCTTCAAAAGAAACAGCATTTC CTACTTTTATACTGTCTATATGATTGATTTGCACAGCTCATCTGGCCAGAAGAGCTGAGACATC CGTTCCCCTACAAGAAACTCTCCCCGGGTGGAACAAGATGGATTATCAAGTGTCAAGTCCAATC TATGACATCAATTATTATACATCGGAGCCCTGCCAAAAAATCAATGTGAAGCAAATCGCAGCCC GCCTCCTGCCTCCGCTCTACTCACTGGTGTTCATCTTTGGTTTTGTGGGCAACATGCTGGTCAT CCTCATCCTGATAAACTGCAAAAGGCTGAAGAGCATGACTGACATCTACCTGCTCAACCTGGCC ATCTCTGACCTGTTTTTCCTTCTTACTGTCCCCTTCTGGGCTCACTATGCTGCCGCCCAGTGGG ACTTTGGAAATACAATGTGTCAACTCTTGACAGGGCTCTATTTTATAGGCTTCTTCTCTGGAAT CTTCTTCATCATCCTCCTGACAATCGATAGGTACCTGGCTGTCGTCCATGCTGTGTTTGCTTTA AAAGCCAGGACGGTCACCTTTGGGGTGGTGACAAGTGTGATCACTTGGGTGGTGGCTGTGTTTG CGTCTCTCCCAGGAATCATCTTTACCAGATCTCAAAAAGAAGGTCTTCATTACACCTGCAGCTC TCATTTTCCATACAGTCAGTATCAATTCTGGAAGAATTTCCAGACATTAAAGATAGTCATCTTG GGGCTGGTCCTGCCGCTGCTTGTCATGGTCATCTGCTACTCGGGAATCCTAAAAACTCTGCTTC GGTGTCGAAATGAGAAGAAGAGGCACAGGGCTGTGAGGCTTATCTTCACCATCATGATTGTTTA TTTTCTCTTCTGGGCTCCCTACAACATTGTCCTTCTCCTGAACACCTTCCAGGAATTCTTTGGC CTGAATAATTGCAGTAGCTCTAACAGGTTGGACCAAGCTATGCAGGTGACAGAGACTCTTGGGA TGACGCACTGCTGCATCAACCCCATCATCTATGCCTTTGTCGGGGAGAAGTTCAGAAACTACCT CTTAGTCTTCTTCCAAAAGCACATTGCCAAACGCTTCTGCAAATGCTGTTCTATTTTCCAGCAA GAGGCTCCCGAGCGAGCAAGCTCAGTTTACACCCGATCCACTGGGGAGCAGGAAATATCTGTGG GCTTGTGACACGGACTCAAGTGGGCTGGTGACCCAGTCAGAGTTGTGCACATGGCTTAGTTTTC ATACACAGCCTGGGCTGGGGGTGGGGTGGGAGAGGTCTTTTTTAAAAGGAAGTTACTGTTATAG AGGGTCTAAGATTCATCCATTTATTTGGCATCTGTTTAAAGTAGATTAGATCTTTTAAGCCCAT CAATTATAGAAAGCCAAATCAAAATATGTTGATGAAAAATAGCAACCTTTTTATCTCCCCTTCA CATGCATCAAGTTATTGACAAACTCTCCCTTCACTCCGAAAGTTCCTTATGTATATTTAAAAGA AAGCCTCAGAGAATTGCTGATTCTTGAGTTTAGTGATCTGAACAGAAATACCAAAATTATTTCA GAAATGTACAACTTTTTACCTAGTACAAGGCAACATATAGGTTGTAAATGTGTTTAAAACAGGT CTTTGTCTTGCTATGGGGAGAAAAGACATGAATATGATTAGTAAAGAAATGACACTTTTCATGT GTGATTTCCCCTCCAAGGTATGGTTAATAAGTTTCACTGACTTAGAACCAGGCGAGAGACTTGT GGCCTGGGAGAGCTGGGGAAGCTTCTTAAATGAGAAGGAATTTGAGTTGGATCATCTATTGCTG GCAAAGACAGAAGCCTCACTGCAAGCACTGCATGGGCAAGCTTGGCTGTAGAAGGAGACAGAGC TGGTTGGGAAGACATGGGGAGGAAGGACAAGGCTAGATCATGAAGAACCTTGACGGCATTGCTC CGTCTAAGTCATGAGCTGAGCAGGGAGATCCTGGTTGGTGTTGCAGAAGGTTTACTCTGTGGCC AAAGGAGGGTCAGGAAGGATGAGCATTTAGGGCAAGGAGACCACCAACAGCCCTCAGGTCAGGG TGAGGATGGCCTCTGCTAAGCTCAAGGCGTGAGGATGGGAAGGAGGGAGGTATTCGTAAGGATG GGAAGGAGGGAGGTATTCGTGCAGCATATGAGGATGCAGAGTCAGCAGAACTGGGGTGGATTTG GGTTGGAAGTGAGGGTCAGAGAGGAGTCAGAGAGAATCCCTAGTCTTCAAGCAGATTGGAGAAA CCCTTGAAAAGACATCAAGCACAGAAGGAGGAGGAGGAGGTTTAGGTCAAGAAGAAGATGGATT GGTGTAAAAGGATGGGTCTGGTTTGCAGAGCTTGAACACAGTCTCACCCAGACTCCAGGCTGTC TTTCACTGAATGCTTCTGACTTCATAGATTTCCTTCCCATCCCAGCTGAAATACTGAGGGGTCT CCAGGAGGAGACTAGATTTATGAATACACGAGGTATGAGGTCTAGGAACATACTTCAGCTCACA CATGAGATCTAGGTGAGGATTGATTACCTAGTAGTCATTTCATGGGTTGTTGGGAGGATTCTAT GAGGCAACCACAGGCAGCATTTAGCACATACTACACATTCAATAAGCATCAAACTCTTAGTTAC TCATTCAGGGATAGCACTGAGCAAAGCATTGAGCAAAGGGGTCCCATAGAGGTGAGGGAAGCCT GAAAAACTAAGATGCTGCCTGCCCAGTGCACACAAGTGTAGGTATCATTTTCTGCATTTAACCG TCAATAGGCAAAGGGGGGAAGGGACATATTCATTTGGAAATAAGCTGCCTTGAGCCTTAAAACC CACAAAAGTACAATTTACCAGCCTCCGTATTTCAGACTGAATGGGGGTGGGGGGGGCGCCTTAG GTACTTATTCCAGATGCCTTCTCCAGACAAACCAGAAGCAACAGAAAAAATCGTCTCTCCCTCC CTTTGAAATGAATATACCCCTTAGTGTTTGGGTATATTCATTTCAAAGGGAGAGAGAGAGGTTT TTTTCTGTTCTGTCTCATATGATTGTGCACATACTTGAGACTGTTTTGAATTTGGGGGATGGCT AAAACCATCATAGTACAGGTAAGGTGAGGGAATAGTAAGTGGTGAGAACTACTCAGGGAATGAA GGTGTCAGAATAATAAGAGGTGCTACTGACTTTCTCAGCCTCTGAATATGAACGGTGAGCATTG TGGCTGTCAGCAGGAAGCAACGAAGGGAAATGTCTTTCCTTTTGCTCTTAAGTTGTGGAGAGTG CAACAGTAGCATAGGACCCTACCCTCTGGGCCAAGTCAAAGACATTCTGACATCTTAGTATTTG CATATTCTTATGTATGTGAAAGTTACAAATTGCTTGAAAGAAAATATGCATCTAATAAAAAACA CCTTCTAAAATAAAAAAAAAAAAAAAAAAAAAAAAAAA Download Select all
Length	3686

CDS Information

Location	2762..3820
CDS Sequence	>gi\|154091329:358-1416 Homo sapiens chemokine (C-C motif) receptor 5 (gene/pseudogene) (CCR5), transcript variant A, mRNA ATGGATTATCAAGTGTCAAGTCCAATCTATGACATCAATTATTATACATCGGAGCCCTGCCAAAAAATCA ATGTGAAGCAAATCGCAGCCCGCCTCCTGCCTCCGCTCTACTCACTGGTGTTCATCTTTGGTTTTGTGGG CAACATGCTGGTCATCCTCATCCTGATAAACTGCAAAAGGCTGAAGAGCATGACTGACATCTACCTGCTC AACCTGGCCATCTCTGACCTGTTTTTCCTTCTTACTGTCCCCTTCTGGGCTCACTATGCTGCCGCCCAGT GGGACTTTGGAAATACAATGTGTCAACTCTTGACAGGGCTCTATTTTATAGGCTTCTTCTCTGGAATCTT CTTCATCATCCTCCTGACAATCGATAGGTACCTGGCTGTCGTCCATGCTGTGTTTGCTTTAAAAGCCAGG ACGGTCACCTTTGGGGTGGTGACAAGTGTGATCACTTGGGTGGTGGCTGTGTTTGCGTCTCTCCCAGGAA TCATCTTTACCAGATCTCAAAAAGAAGGTCTTCATTACACCTGCAGCTCTCATTTTCCATACAGTCAGTA TCAATTCTGGAAGAATTTCCAGACATTAAAGATAGTCATCTTGGGGCTGGTCCTGCCGCTGCTTGTCATG GTCATCTGCTACTCGGGAATCCTAAAAACTCTGCTTCGGTGTCGAAATGAGAAGAAGAGGCACAGGGCTG TGAGGCTTATCTTCACCATCATGATTGTTTATTTTCTCTTCTGGGCTCCCTACAACATTGTCCTTCTCCT GAACACCTTCCAGGAATTCTTTGGCCTGAATAATTGCAGTAGCTCTAACAGGTTGGACCAAGCTATGCAG GTGACAGAGACTCTTGGGATGACGCACTGCTGCATCAACCCCATCATCTATGCCTTTGTCGGGGAGAAGT TCAGAAACTACCTCTTAGTCTTCTTCCAAAAGCACATTGCCAAACGCTTCTGCAAATGCTGTTCTATTTT CCAGCAAGAGGCTCCCGAGCGAGCAAGCTCAGTTTACACCCGATCCACTGGGGAGCAGGAAATATCTGTG GGCTTGTGA Download Select all
CCDS ID	CCDS2739.1

Protein Information

Protein ID	NP_000570.1
Protein Name	Chemokine (C-C motif) receptor 5
Molecular Wt. (Da)	40393
Protein Sequence	>1234 MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKRLKSM TDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFIILLTIDRYL AVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSSHFPYSQYQFWKN FQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTIMIVYFLFWAPYNIVLL LNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFVGEKFRNYLLVFFQKHIAKRF CKCCSIFQQEAPERASSVYTRSTGEQEISVGL Download Select all
Length	352
Uniprot ID	P48023
Ensembl Protein ID	ENSP00000344739

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
Y	Sulfation	10
Y	Sulfation	14
Y	Sulfation	15
C	Palmitoylation	321
C	Palmitoylation	323
C	Palmitoylation	324
Y	Sulfation	3
S	Glycosylation	6
S	Phosphorylation	336
S	Phosphorylation	337
S	Phosphorylation	342
S	Phosphorylation	349

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
156	ADRBK1	182	NP_001610.2	in vivo	10085131
174	AFP	74	NP_001125.1	in vitro;in vivo	12176010
408	ARRB1	146	NP_004032.2	in vitro	12065593
920	CD4	1740	NP_000607.1	in vivo	10816381
1231	CCR2	3166	NP_000638.1	in vivo	11350939
2185	PTK2B	3131	NP_004094.3	in vivo	9446638
2770	GNAI1	756	NP_002060.4	in vivo	15251452
2771	GNAI2	764	NP_002061.1	in vivo	15251452
2773	GNAI3	765	NP_006487.1	in vivo	15251452
2775	GNAO1	757	NP_066268.1	in vivo	15251452
2776	GNAQ	2998	NP_002063.2	in vivo	15251452
3716	JAK1	992	NP_002218.2	in vivo	10037796
3717	JAK2	993	NP_004963.1	in vivo	11591716
3932	LCK	1080	NP_005347.3	in vivo	11591716
5004	ORM1	724	NP_000598.2	in vitro	11336643
5686	PSMA5	1464	NP_002781.2	in vivo;yeast 2-hybrid	11877445
5747	PTK2	2859	NP_005598.3	in vitro;in vivo	10384144
6347	CCL2	1149	NP_002973.1	in vivo	10477718
6348	CCL3	1656	NP_002974.1	in vitro;in vivo	1 170 007 310 477 710
6351	CCL4	1657	NP_002975.1	in vitro;in vivo	124 270 158 663 314
6352	CCL5	1751	NP_002976.2	in vitro;in vivo	92 890 168 663 314 100 000 000 000 000 000 000 000
6354	CCL7	1150	CAA50405.1	in vitro	10477718
6356	CCL11	3098	NP_002977.1	in vitro;in vivo	1 126 415 210 477 710
6772	STAT1	2777	NP_009330.1	in vivo	14674010
6774	STAT3	26	NP_644805.1	in vivo	14674010
7294	TXK	2505	NP_003319.2	in vivo	11859127
7852	CXCR4	1217	NP_001008540.1	in vitro	12429730
11230	PRAF2	6596	NP_009144.1	in vivo;yeast 2-hybrid	15757671

Pathway Information

Pathway Name	Pathway ID
Chemokine signaling pathway	hsa04062
Cytokine-cytokine receptor interaction	hsa04060
Endocytosis	hsa04144
Toxoplasmosis	hsa05145
Viral carcinogenesis	hsa05203

Structure Information

No matching records could be found.

Domain Information

ID	Location	Description
pfam00001	59-297	7tm_1
PHA03087	36-304	PHA03087
PHA02638	6-320	PHA02638
PHA02834	13-314	PHA02834
PHA03235	50-319	PHA03235
PHA03234	62-321	PHA03234

Ontology Information

HPRD ID	610
Molecular Class	Cell surface receptor
Molecular Function	Receptor binding (GO:0005102)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report