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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 25394863 | 2015 | Cell line : Colo320, SW480, SW620 Source : - Sample Type : - No. of Sample : - Stage : - | MTT assays,Western blotting | Up-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | CD molecules, "Immunoglobulin superfamily / V-set domain containing" |
| Description | The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] | Chromosome | 6 |
| Location | 6p23 |
| Start | 14117487 |
| End | 14137149 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 19663 |
| OMIM ID | 604534 |
| HGNC ID | HGNC:1703 |
| Unigene ID | Hs.595133 |
| Ensembl ID | ENSG00000112149 |
| PharmGKB ID | PA26241 |
Protein Information
| Protein ID | NP_001035370.1 |
|---|---|
| Protein Name | CD83 molecule |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 205 |
| Uniprot ID | Q6NYC1 |
| Ensembl Protein ID | ENSP00000380750 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| T | Phosphorylation | 188 |
| T | Phosphorylation | 198 |
| T | Phosphorylation | 187 |
| T | Phosphorylation | 197 |
| N | Glycosylation | 79 |
| N | Glycosylation | 86 |
| N | Glycosylation | 79 |
| N | Glycosylation | 86 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd05877 | 29-129 | Ig_LP_like |
| cl11960 | 29-129 | Ig superfamily |
| cd00096 | 31-119 | Ig |
| cd05714 | 28-129 | Ig_CSPGs_LP |
| pfam13895 | 28-126 | Ig_2 |
| pfam13927 | 17-110 | Ig_3 |
| pfam00047 | 28-109 | ig |
| smart00410 | 21-126 | IG_like |
| smart00409 | 21-126 | IG |
| pfam07679 | 23-115 | I-set |
Ontology Information
| HPRD ID | 5814 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Transporter activity (GO:0005215) |
| Biological Process | Protein metabolism (GO:0019538); Transport (GO:0006810) |
Drug Information
No matching records could be found.