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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CDCP1 | 64866 | CUB domain containing protein 1 | 3 | CD318, SIMA135 |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 11466621 | 2001 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | cDNA chip technology, FISH,real time RT-PCR | Up-regulation | - | - |
| 17335815 | 2007 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | - | Up-regulation | - | - |
| 25820997 | 2015 | Cell line : - Source : National Taiwan University Hospitals. Sample Type : CRC tumor and normal tissue No. of Sample : 101 Stage : - | real time RT-PCR, Invitro migration and invasion assay | Up-regulation | - | CDCP1 as a key regulator of CRC migration and invasion, and suggest that it is a useful prognostic factor for patients with CRC. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | CD molecules |
| Description | This gene encodes a transmembrane protein which contains three extracellular CUB domains and acts as a substrate for Src family kinases. The protein plays a role in the tyrosine phosphorylation-dependent regulation of cellular events that are involved in tumor invasion and metastasis. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, May 2013] | Chromosome | 3 |
| Location | 3p21.3 |
| Start | 45123766 |
| End | 45187914 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 64149 |
| OMIM ID | 611735 |
| HGNC ID | HGNC:24357 |
| Unigene ID | Hs.476093 |
| Ensembl ID | ENSG00000163814 |
| PharmGKB ID | PA142672140 |
Protein Information
| Protein ID | NP_073753.3 |
|---|---|
| Protein Name | CUB domain containing protein 1 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 836 |
| Uniprot ID | Q8WYH8 |
| Ensembl Protein ID | ENSP00000322142 |
Post-translational Modification Information (Source : HPRD)
| Residue | Type | site |
|---|---|---|
| Y | Phosphorylation | 734 |
| R | Proteolytic Cleavage | 368 |
| S | Phosphorylation | 797 |
| S | Phosphorylation | 803 |
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 5340 | PLG | 1417 | NP_000292.1 | in vivo | 14739293 |
| 5580 | PRKCD | 1501 | NP_006245.2 | in vitro;in vivo | 15851033 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Ontology Information
| HPRD ID | 6946 |
|---|---|
| Molecular Class | Unclassified |
| Molecular Function | Growth factor activity (GO:0008083) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.