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General Information
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24898286 | 2015 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : 89 GC and 131 CRC (high MSI (MSI-H) or stable MSI/low MSI (MSS/MSI-L)). Stage : - | SSCP and DNA sequencing | Frameshift Mutation | - | Results show that unconventional CDH10, CDH24 and DCHS2 genes harbored frameshift mutations. These mutations might inactivate the cell adhesion-related functions and could be a feature of GC and CRC with MSI-H. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Cadherins / Major cadherins |
| Description | - | Chromosome | 14 |
| Location | 14q11.2 |
| Start | 23516270 |
| End | 23526747 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 10478 |
| OMIM ID | - |
| HGNC ID | HGNC:14265 |
| Unigene ID | Hs.155912 |
| Ensembl ID | ENSG00000139880 |
| PharmGKB ID | PA26297 |
Protein Information
| Protein ID | NP_071923.2 |
|---|---|
| Protein Name | cadherin 24, type 2 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 819 |
| Uniprot ID | Q9BX63 |
| Ensembl Protein ID | ENSP00000259008 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 1499 | CTNNB1 | 286 | NP_001895.1 | in vivo | 12734196 |
| 1500 | CTNND1 | 3026 | NP_001078927.1 | in vivo | 12734196 |
| 84988 | PPP1R16A | 16454 | NP_116291.1 | yeast 2-hybrid | 16169070 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd11304 | 154-255 | Cadherin_repeat |
| cl15786 | 154-255 | CA_like superfamily |
| cd11304 | 379-513 | Cadherin_repeat |
| cl15786 | 379-513 | CA_like superfamily |
| cd11304 | 264-368 | Cadherin_repeat |
| cl15786 | 264-368 | CA_like superfamily |
| cd11304 | 51-146 | Cadherin_repeat |
| cl15786 | 51-146 | CA_like superfamily |
| pfam01049 | 663-812 | Cadherin_C |
| cl03079 | 663-812 | Cadherin_C superfamily |
| smart00112 | 173-257 | CA |
| smart00112 | 70-148 | CA |
| pfam00028 | 379-455 | Cadherin |
| pfam00028 | 264-366 | Cadherin |
| pfam00028 | 155-249 | Cadherin |
| smart00112 | 282-367 | CA |
| smart00112 | 397-515 | CA |
| pfam00028 | 52-141 | Cadherin |
| cd00031 | 53-146 | CA_like |
| pfam00028 | 521-615 | Cadherin |
| cl15786 | 521-615 | CA_like superfamily |
| cd00031 | 382-455 | CA_like |
Ontology Information
| HPRD ID | 5913 |
|---|---|
| Molecular Class | Adhesion molecule |
| Molecular Function | Receptor activity (GO:0004872) |
| Biological Process | Regulation of endocytosis (GO:0030100) |
Drug Information
No matching records could be found.