Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CHST10 | 9486 | carbohydrate sulfotransferase 10 | 2 | HNK-1ST |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 24393480 | 2014 | Cell line : - Source : - Sample Type : CRC tumor and normal tissue No. of Sample : - Stage : - | Illumina bead chip array,methylation-specific PCR | Methylation | - | These results suggest that these novel hypermethylated genes AKR1B1, CHST10, ELOVL4, SOX5, STK33, and ZNF304 may be potential methylation biomarkers and therapeutic targets of vincristine in CRC. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Sulfotransferases, membrane-bound |
| Description | This protein encoded by this gene transfers sulfate to the C-3 hydroxyl of terminal glucuronic acid of protein- and lipid-linked oligosaccharides. This protein was first identified as a sulfotransferase that acts on the human natural killer-1 (HNK-1) glycan; HNK-1 is a carbohydrate involved in neurodevelopment and synaptic plasticity.[provided by RefSeq, Feb 2011] | Chromosome | 2 |
| Location | 2q11.2 |
| Start | 101008322 |
| End | 101034130 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 25809 |
| OMIM ID | 606376 |
| HGNC ID | HGNC:19650 |
| Unigene ID | Hs.516370 |
| Ensembl ID | ENSG00000115526 |
| PharmGKB ID | PA134920179 |
Protein Information
| Protein ID | NP_004845.1 |
|---|---|
| Protein Name | carbohydrate sulfotransferase 10 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 356 |
| Uniprot ID | Q8NF91 |
| Ensembl Protein ID | ENSP00000356222 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
No matching records from HPRD source could be found.
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Other types of O-glycan biosynthesis | hsa00514 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| pfam03567 | 116-348 | Sulfotransfer_2 |
| cl22970 | 116-348 | Sulfotransfer_2 superfamily |
Ontology Information
| HPRD ID | 5875 |
|---|---|
| Molecular Class | Enzyme: Sulphotransferase |
| Molecular Function | Ribonuclease activity (GO:0004540) |
| Biological Process | Gene silencing (GO:0016458) |
Drug Information
No matching records could be found.