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General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CITED4 | 163732 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 | 1 | - |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 26243458 | 2015 | Cell line : SW480 Source : - Sample Type : - No. of Sample : - Stage : - | real time RT-PCR, Western blotting | Up-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | - |
| Description | The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and regulate gene transcription. This protein also interacts with transcription factor AP2 (TFAP2), and thus may function as a co-activator for TFAP2. Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer recurrence-free and overall survival of patients with oligodendroglial tumors. [provided by RefSeq, Aug 2011] | Chromosome | 1 |
| Location | 1p34.1 |
| Start | 41326728 |
| End | 41328018 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 1291 |
| OMIM ID | 606815 |
| HGNC ID | HGNC:18696 |
| Unigene ID | Hs.355820 |
| Ensembl ID | ENSG00000179862 |
| PharmGKB ID | PA38643 |
Protein Information
| Protein ID | NP_597724.1 |
|---|---|
| Protein Name | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4 |
| Molecular Wt. (Da) | 0 |
| Protein Sequence | Download Select all |
| Length | 184 |
| Uniprot ID | Q6R327 |
| Ensembl Protein ID | ENSP00000296782 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 2033 | EP300 | 4078 | NP_001420.2 | in vitro;in vivo | 11744733 |
| 7020 | TFAP2A | 128 | NP_003211.1 | in vitro | 11744733 |
| 7021 | TFAP2B | 3360 | NP_003212.2 | in vitro | 11744733 |
| 7022 | TFAP2C | 3361 | NP_003213.1 | in vitro | 11744733 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Ontology Information
| HPRD ID | 10682 |
|---|---|
| Molecular Class | Transcription regulatory protein |
| Molecular Function | Molecular function unknown (GO:0005554) |
| Biological Process | Biological_process unknown (GO:0000004) |
Drug Information
No matching records could be found.