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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
CIZ1 25792 CDKN1A interacting zinc finger protein 1  9LSFR1, ZNF356 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
24126760   2013Cell line : RKO

Source : -

Sample Type : -

No. of Sample : -

Stage : -

Silencing of CIZ1, Flow cytometric analysis, real time RT-PCRUp-regulation- CIZ1 was observed to be highly expressed in RKO human CRC cells.


Gene Details



NC_000009.11 (130928344..130966662, complement)

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Gene Type protein coding
Gene Family -
Description The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]  
Chromosome 9
Location 9q34.1
Start 130928344  
End 130966662  
Strand -  
Gene Sequence

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Length 38319  
OMIM ID 611420   
HGNC ID HGNC:16744   
Unigene ID Hs.212395   
Ensembl ID ENSG00000148337   
PharmGKB ID PA134883336   

mRNA Information


mRNA ID ?NM_001131015.1
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS48033.1



Protein Information


      
Protein IDNP_001124487.1
Protein NameCDKN1A interacting zinc finger protein 1
Molecular Wt. (Da)0
Protein Sequence

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Length 898  
Uniprot IDQ9NY30
Ensembl Protein ID ENSP00000348300  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation868;-
TPhosphorylation876
TPhosphorylation841
SPhosphorylation45
TPhosphorylation347
SPhosphorylation350
TPhosphorylation567
TPhosphorylation585
SPhosphorylation838

Enzyme Information


No matching records could be found.

PPi Information


(Click to view network : Source STRING)      View   

               
Interactant Gene ID (Source: HPRD) Gene Symbol HPRD ID Ref Seq ID Technique References
1026CDKN1A298NP_510867.1in vitro10529385   


Pathway Information


No matching records could be found.

Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam12171686-710  zf-C2H2_jaz
cl23617686-710  zf-C2H2_jaz superfamily
smart00451592-621  ZnF_U1
cl22907592-621  zf-U1 superfamily
COG5112666-717  UFD2
cl23455666-717  UFD2 superfamily
smart00451798-831  ZnF_U1
cl22907798-831  zf-U1 superfamily
PHA03247129-482  PHA03247
pfam09770178-480  PAT1
PHA03247117-496  PHA03247
pfam09606273-580  Med15
PRK14960165-350  PRK14960
PRK10263386-476  PRK10263


Ontology Information


   
HPRD ID7876
Molecular ClassDNA binding protein
Molecular FunctionMolecular function unknown (GO:0005554)
Biological ProcessBiological_process unknown (GO:0000004)  



SNP Information


View SNP Geneview Report   

Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO