CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
COL1A1	1277	collagen, type I, alpha 1	17	OI4

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
24332065	2013	Cell line : - Source : - Sample Type : - No. of Sample : - Stage : -	-	Up-regulation	-	collagen I might be an early event during tumorigenesis of CRC, and might contribute to the metastasis of CRC under the degradation regulated by some specific proteases.

Gene Details

Chromosome 17 - NC_000017.11 (50184096..50201648, complement)
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Gene Type	protein coding
Gene Family	Collagens
Description	This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Chromosome	17
Location	17q21.33
Start	50184096
End	50201648
Strand	-
Gene Sequence	>gi\|568815581:c50201648-50184096 Homo sapiens chromosome 17, GRCh38.p2 Primary Assembly CCGGGCCAGTCGTCGGAGCAGACGGGAGTTTCTCCTCGGGGTCGGAGCAGGAGGCACGCGGAGTGTGAGG CCACGCATGAGCGGACGCTAACCCCCTCCCCAGCCACAAAGAGTCTACATGTCTAGGGTCTAGACATGTT CAGCTTTGTGGACCTCCGGCTCCTGCTCCTCTTAGCGGCCACCGCCCTCCTGACGCACGGCCAAGAGGAA GGCCAAGTCGAGGGCCAAGACGAAGACAGTAAGTCCCAAACTTTTGGGAGTGCAAGGATACTCTATATCG CGCCTTGCGCTTGGTCCCGGGGGCCGCGGCTTAAAACGAGACGTGGATGATCCGGAGACTCGGGAATGGA AGGGAGATGATGAGGGCTCTTCCTCGGCGCCCTGAGACAGGAGGGAGCTCACCCTGGGGCGAGGTTGGGG TTGAACGCGCCCCGGGAGCGGGAGGTGAGGGTGGAGCGCGGCGTGAGTTGGTGCAAGAGAGAATCCCGAG CGCGCAACCGGGGAAGTGGGGATCTGGGTGCAGAGTGAGGAAAGCACGTCGAAGATGGGATGGGGGCGCC GAGCGGGGCATTTGAAGCCCAAGATGTAGAAGCAATCAGGAAGGCCGTGGGATGATTCATAAGGAAAGAT TGCCCTCTCTGCGGGCTAGAGTGTTGCTGGGGCCGTGGGGGTGCTGGGCAGCCGCGGAGGGGGTGCGGAG CGTGGGCGGGTGGAGGATGAGAAACTTTGGCGCGGACTCGGCGGGGCGGGGTCCTTGCGCCCCCTGCTGA CCGATGCTGAGCACTGCGTCTCCCGGTCCAACGCTTACTGGGGCAGGAGCCGGAGCGGGAAGACCCGGGT TATTGCTGGGTGCGGACCCCCACCTCTAGATCTGGAAAGTAAAGCCAGGGATGGGGCAGCCCAAGCCTCT TAAAGAGGTAGTCGGGCCGGTGAGGTCGGCCCCGCCCCGGCCCCATTGCTTAGCGTTGCCCGACACCTAG TGGCCGTCTGGGGAGCCGCTAGCGCGGTGGGAGTGGTTAGCTAACTTCTGGACTATTTGCGGACTTTTTG GTTCTTTGGCTAAAAGTGACCTGGAGGCATTGGCTGGCTTTGGGGGACTGGGGATGGCCCCGAGAGCGGG CTTTTAAGATGTCTAGGTGCTGGAGGTTAGGGTGTCTCCTAATTTTGAGGTACATTTCAAGTCTTGGGGG GGCCTCCCTTCCAATCAGCCGCTCCCATTCTCCTAGCCCCGCCCCCGCCACCCCACCTGCCCAGGGAATG GGGGCGGGATGAGGGCTGGACCTCCCTTCTCTCCTCCCTCGCCCTCCTCCTGTCTCTACCACGCAAGCCA CTCCCCACGAGCCTGCCCTCCCGATGGGGCCCCTCCTATTCTCCCCCCGCCCTCCCCCTCTCACCCTGTG GTTTTTATTTCACTTGGCTTCAGCGCCAATGGGCTGAGGTTGGAGTTGGAAGCCACCGCGGACTAAAGCT TTGTTTAAATTCCTGAGAACTGGAAAGAGTTACAGCCTCCCTGGCCAGGCGCCTCGGCGCTGTCACCCGC GCTGATGAGGAGCAGGCGAGCTTTTAAGGATTTGAGGAAAGAAGAACGGGGGGAGGGGCGGGAAGTGAAA AATCCAAGTGTGCCTCTTAGACCCGGGGGAAAGGTGGTTAAGCTGGGGGTTGCAGTCACTACTGACAACG CCCCTCTTCCGCCTGTCCCAGTCCCACCAATCACCTGCGTACAGAACGGCCTCAGGTACCATGACCGAGA CGTGTGGAAACCCGAGCCCTGCCGGATCTGCGTCTGCGACAACGGCAAGGTGTTGTGCGATGACGTGATC TGTGACGAGACCAAGAACTGCCCCGGCGCCGAAGTCCCCGAGGGCGAGTGCTGTCCCGTCTGCCCCGACG GCTCAGGTGCGGCTGCGCTCGGGGCCTGGGGCCTGGGGCCTGGGGCCTGGGGCCTGGGGCTGGGGCTGGG GGTGGTCGGCGCTCGCTGGCCCTCCGTGCTGGAGGCCTCTGCCGACGGGAGCAGCATTAGCAAACCTTGG CTCTAACGCGCGTCTCTTCGTCCCCTAGAGTCACCCACCGACCAAGAAACCACCGGCGTCGAGGTAATCT CCTGCCCTCGAATTTTGCCCCTGCGCGGCCCGTGACTCCTCACAGTCCTCCCTTCTCTAACCTGGCCTCT TGTTTCTTCTCCCCCAATCCCACAGGGACCCAAGGGAGACACTGGCCCCCGAGGCCCAAGGGTAAGCGTT GCACTCTGGGCTGTGGGGGGCTGCAGGTGGGCATGGCTCTCGGCCCCACGCTCACCCCGGCCCCGCCCTC TCCCCCTGCAGGGACCCGCAGGCCCCCCTGGCCGAGATGGCATCCCTGGACAGCCTGGACTTCCCGGACC CCCCGGACCCCCCGGACCTCCCGGACCCCCTGGCCTCGGAGGAGTAAGTGGAGAGGCCTTGTGTGTCCAC TCTCCCCTGTTTTGTTTTTGTTTTTTGGCAGATGACATAATTTTATACTTTGAAATAATTTCAAACTTAC AGAAAAGTTGCAAGAATCCTACAGGAAACTCTCACATACCCTTCACAGTTTGTGACATGTGCTTTATTAG TCTCTGTTTATGTATATGTATCTTTTTTTTTCTGAACTGTTTGAGCAAGTTGCTAACATCAGGCTCTTTT GCGCCTAAATACTTAGGTGTGTTTTTCCTAAAAACAAGAGCATTCTCTTAACTGACCTACACAATGATTA AATTCACTCTCTAATGTGCAGTCCGTATTCAAAGTTCACCGATGTCCCGATAATGTCCTTTATAGATTCC ACCCCCCACCACCCCAATCTGGGATCCAGTCCAGGATTATGTATTGCGTTTAATCATCATGTCTCTAGTT TCCACAAATGTAGAACGTTCCTCAGACTTTCTTTGTCTTTAGTGGCACTGGGAGTTTTGATGAGTCCAGT TGTTTTGCAGACTGTCCCTCAATTTGGGATTGTCTCATTAGATTAGATGCAGGGATGCATCTTTGCAGGA ATGTCTTAAAAGCAATGTTATTCTTCTCAGCACATCACACCAGGAAGTGCATGATGTCAGTTTCTTCCAT CCTCAGTGCCGTCTTCTGCCTTTCAATTCACTGTCCTCACTCTGACTTCTCTTGTTTGTTCTAGAACTTT GCTCCCCAGCTGTCTTATGGCTATGATGAGAAATCAACCGGAGGAATTTCCGTGCCTGGCCCCATGGTGA GCCAGCAGGGGGAGCATGGATGACAGAAGAGAGAATGGGTATCCAGAGGAGGTGGGCATAGGCGGCTGGT ATAGACAGCTTGGGAGGTCCAGATCACCTTTGGGACCTCAGAGTCCAGAAAGGATGCAGGACGACTGGGT GGTCCCAACAGGCATGAATGACTACATCCACATGCTTTCCTACAGAGGGATCACCATGACCCCCCTTTCT TCTCCCTCTATAGGGTCCCTCTGGTCCTCGTGGTCTCCCTGGCCCCCCTGGTGCACCTGTGAGTATCCAG GACGTCTTCATATGCCTCCTTGGGCTTTGGTCTTTTGGAGGGAAGACTGGGATGAGGGCAGGAGAGATGC TCAGAGATCTCTTGGTAAGATTGGAGAAGGTTGACAGGGACTTGTCTTCTAACCCATCTTTTTCCTTCTT CTCAAGGGTCCCCAAGGCTTCCAAGGTCCCCCTGGTGAGCCTGGCGAGCCTGGAGCTTCAGTAAGCACTC TCTATACAGATTCATACTCCTTCTACAAACACACAGACTCTCCTATAGAAGAACTCCCAGGCCTGGGGTC TTCCTTACCTCTTCCCTTCAATCCCAGCCTTCCCCTTCTTTTTTTCTTATCCATATTCTAACCACCTCTT CTATCTTTTCTAGGGTCCCATGGGTCCCCGAGGTCCCCCAGGTCCCCCTGGAAAGAATGGAGATGATGTA AGTATCCCCAGCAAGAAGATACCATCTGACCCCATGGCCTCCATGGGTTGGGTCCTGCAATTTCCACTCC ACCACATTTGGGAACGATACTCAGAGGAAGGAGGGCAAGTCCTCTCTGATGCACGGACTGCCCTGGAACA ATGATCTTTTCGCTTAGTGAGATGATTCCATGTCCCCAACAAAGTGACTGTTCTCCTCACCCCAGCCACC TTAGAGCAATCCCCAACCCCATCCCTTTGGGGAAATTGGTGCGCAGATGGTGAAATTAAAATGCTGGTGA CAGAAGTAGACAGAAATTCCTTTAGAGGCACTCAGATTTCACCAAACGAAGGTTTCACTGTAGATTTAAA CTGAGCTCTAGATTCAAAGATAAGATTCTGGGCCCCCAAACCTGACCTGCAACAATCCAAAGAAGACTGA GACCTTCTCCACTTTTCCAGCCCCTAGGCGGTGGTGGGGAGGCAGAGGCATGATGGTCTTTTCTCTCCCT CTCAGGGGGAAGCTGGAAAACCTGGTCGTCCTGGTGAGCGTGGGCCTCCTGGGCCTCAGGTGAGCAGGGG GCTGTGGCTGAACCTGGGCTTCACTGCACTTGGGCTTCATTTAGGAGCTGGGTCCACAGTGATGTGTTCT AATGGCCCTTCCTTGTCTTCTTCATCTCTCTCCAGGGTGCTCGAGGATTGCCCGGAACAGCTGGCCTCCC TGGAATGAAGGGACACAGAGTGAGTCACCTTTGAGTCATTTAAGCTCCCCAAGTCCCTAGCATACCCCCA TCCAGTCCCAACCTCTTCCCCAAAAGATACTGAGTTGCATCATGGTGGGTGGCAGCTACAGAAGTCCCAA GGGACAGAGAGTGGACATCCAAAAGCACCTCCCTCCATGGGAAAGCAGTCCCGATTAAACGATTGGGTGA GATCTAGAGCCAGTTGGGGTTTAGTCTAGCTCAGAAACAAAGGGATGGCGGTGATGACCTCCCAAGGCTC TTTCTCAGATCTAGGTGGATGTCAAGGCTGTTCCACCCCCTCCACAGGTTCTTACCTTCTACCTCTTTCC TGCTTTAGGGTTTCAGTGGTTTGGATGGTGCCAAGGGAGATGCTGGTCCTGCTGGTCCTAAGGTAAGAGG CTGTCTGAACATCATGGTCCTCCACATCCCCAGAGTCCCACCATGAATGAATTTCTCACTCATTATTCTC TGATCTACAGGGTGAGCCTGGCAGCCCTGGTGAAAATGGAGCTCCTGGTCAGATGGTGAGTGTGCCCAGT TCCAGAGGGCAGGGATGGGGCAGGAGGCAGGGGCAAGATGGAGGCCTGGGGGAACAAGGCTGTCTCCCAT CTCATCTGACTTCTCTTGGTTTGGTTGTCAGGGCCCCCGTGGCCTGCCTGGTGAGAGAGGTCGCCCTGGA GCCCCTGGCCCTGCTGTAAGTACTCCTGGCCCCTTGGGGGATCCCTGAGCTCTGGAAGGGGCTCCCCAGG AACTCTAGGGACTGGCCAGTGCTCAGTGGACTTAACGGGGCTTCCCCTCTCTCCTGCAGGGTGCTCGTGG AAATGATGGTGCTACTGGTGCTGCCGGGCCCCCTGTGAGTGTGGCCTGTAGGCCTCAGGGCCTGGGAGTG GGGAGGGGTCTCAGTATCTGCTCTTGGGGCTGACAATGGGAGCAGGTTATGTTGGTCTGAACCCCAGGAC TTCCTCTGTCCCAGGGTGTGACTTGCAGCTGCCATCTCTTCCTTCTCGCTGACATCTCCATTTCATTCAC AGGGTCCCACCGGCCCCGCTGGTCCTCCTGGCTTCCCTGGTGCTGTTGGTGCTAAGGTGAGACCCCCCAC TCTCCTCTAAGCATGACCCTCATGGGCCAAGGGGTTCATGTCTCCCTGTTCCCCAAACCAAAGGGACCCA GAGTGGCAAGAGAGCAGCCCGTTCACTAACACCTTTGTCCTGGGTTCTCCGTCTCTGATCTTAGAGTCCT GATCATTGCTCTCCTGTCCCTGTCTCCCCTTCCTCCTGCCATCCCGAGAGGCAAGGTTGGGTTTCCCAGG GTGGCTTCTGATATGTCCTTTCTTCTGATTCAGGGTGAAGCTGGTCCCCAAGGGCCCCGAGGCTCTGAAG GTCCCCAGGGTGTGCGTGGTGAGCCTGGCCCCCCTGGCCCTGCTGGTGCTGCTGGCCCTGCTGTAAGTGT CCCCGACTCAGTGTCCCCTTTGCCACTTTCTAACCTCAGAGTCCTTGCCTGTTGCTGACACTCCTTTCTC TGTGCCACAGGGAAACCCTGGTGCTGATGGACAGCCTGGTGCTAAAGGTGCCAATGTAAGTATCCTGCCA GGCTTCAGTCCCACTCCTGCCGCCTGCAGCCTGCCTGCCCCTTTCCCTCTGCTCCTAGGCTCACGCCCTG GCTGTCTGCCTCCCACAGGGTGCTCCTGGTATTGCTGGTGCTCCTGGCTTCCCTGGTGCCCGAGGCCCCT CTGGACCCCAGGGCCCCGGCGGCCCTCCTGGTCCCAAGGGTAACAGCGTGAGTACCAAACTCTCCCTTCT GCCCACCCCATGCACTGGCTCCAGTGCGGCTCTCATCTGGGGAGCAGGAAGACGCAGGCCAACTGAGCGC CCCCGACTCTCAGCTCATCCTCTTCTCCCCCCTTGCAGGGTGAACCTGGTGCTCCTGGCAGCAAAGGAGA CACTGGTGCTAAGGGAGAGCCTGTAAGTCTCCCCGCCATCCTTCTTGCAGCCCAGCCCACCCTGCCCTAG GAGCCCCCTGAGGGAAATCCAGAAAGGAAGAGGAGCCCCTAGTCTTCTGGGGGAGTCCCTGCCACACCCC CAGGAACCCCTGACACTGGAGGCCCAGCCTCAGCCGGCTCTGAGGCTGGCACAGGATGGCCCCTCACCAC AGGCCGCCTCCTCCTCTCGGCCCTCTCCAGGGCCCTGTTGGTGTTCAAGGACCCCCTGGCCCTGCTGGAG AGGAAGGAAAGCGAGGAGCTCGAGGTGAACCCGGACCCACTGGCCTGCCCGGACCCCCTGGCGAGCGTGT AAGTGTCCCTGCCCGCCCCCTCCCGCTCCACCCTCATTGCCTGGCTGGTGCCTGTGTGTCGCGGAGTTCA CTGGCCTCCTCTCCTCCTGCAGGGTGGACCTGGTAGCCGTGGTTTCCCTGGCGCAGATGGTGTTGCTGGT CCCAAGGTAACCTCTCCTTGCGGCCGGGGGGCTGACCCTGCCGCTCCCTGGGCATCTTCTTCCTCTTTTG GCCCGTGGCAAAGAGCCACAAACTTGAGACCCTAACTGTTCCTGTGACTTCCCCCAACCAGGGTCCCGCT GGTGAACGTGGTTCTCCTGGCCCTGCTGGCCCCAAAGGATCTCCTGGTGAAGCTGGTCGTCCCGGTGAAG CTGGTCTGCCTGGTGCCAAGGTGAGGCCCCAGGCTTTCAGCCTGGCTTGGCCAGGCCCTGACCATCCCGT GTAGGGTCTGGGATGAGGCGTTCTGGATCAGGCCCAAGGGTCTGCCCTCTGGAGTCCTCCCCCACCTCCA TCATGCTTCTCCCCAAGTCCCACTCATACCTCTCTGCCTCCCTAGGGTCTGACTGGAAGCCCTGGCAGCC CTGGTCCTGATGGCAAAACTGGCCCCCCTGTAAGTATCACTCCCCCTGAACCCCCTGCCATTGTCCTGTC TGCCTCCCTGCTGTCCTCACTGCTGCTTTCGTGCCTCCCATCCTTAGGGTCCCGCCGGTCAAGATGGTCG CCCCGGACCCCCAGGCCCACCTGGTGCCCGTGGTCAGGCTGGTGTGATGGGATTCCCTGGACCTAAAGGT GCTGCTGTGAGTATTAAGTGAGGATCCATGAAGAGCCAGGGACAAACACACCTGAGACTTGAAGGAGTCC TGGGCTCTGGGCTCAGCTGTGCCGCTGACCTGCCGTGTGGCCACTCACTCTCACTTTCTGGACCTCAGCC TCCCTATCTGTAAAATGAAAGACTTCTCGGCGGGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGG GAGGCCAAGGCGGGCAGACCATGAGGTCAGGAGTTTGAGACCAGTCGGGCCAACATAGTGAAACCACGTC TCTACTAAAAATACAAAAGATTAGCTGGGTGTGGTGGTGTGCACCTGTAACCCCAGCTAGTCAGGAGGCT GAGGCAGGAGAATTGCATGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCACGCCATTGCACTCCA GCCTGGGCAACAGTGCGAGATTCCATCTCAAAAAAAAAAAAAAAGAAGAAAGAAAGAAAGAAAAAATGAA ACACTTCTCCAGGCTCCATGACCACTGCTCTGTCCTGGAAATAAGTGTTGTTGGTGGCCCTCCACCCCGA CACGTGGGGATAGGACAGGCCTTTGATATGATAGGCACCCCCAGTCTTGGTGGATTCTTTGAGGTCCAAA AGGAGATAGCAGAGAAGATGAAAGCCCTTTGCAGTGCAGGCCACAGCGGGCATCTAACAGGGAAAAGGCA GAGGAGCCTGGAAGGGCATCTTGGGAGGAGTGGGCTCAGAAAGGGCCCAGCAAGAAGCACCTGCAGGGGC ATTCCCCGGGGGCCAAACAGTCTTTTGAAAAGAAAGTCCCTTAAAAAGTCCCACTCAGAGTAAATGAGAG GCCCCAGGAGGCCCTGGCTTCTCACTTCAGCCCCCTCAACCCTAACTCCCTTTCTCCACAGGGAGAGCCC GGCAAGGCTGGAGAGCGAGGTGTTCCCGGACCCCCTGGCGCTGTCGTAAGTATCTCCTTTCCATCCCTAC CTCCTTCCCATTGCTGCCCCGGCACTTTCTCCTCCCTGCAGGAGGGGTGCTAGAGGCCACGGTCCTCAGC TGCTCGGGGCCTCCTAACCCTGAGTTCCCCTTTGCTCTCTCCCTGCAGGGTCCTGCTGGCAAAGATGGAG AGGCTGGAGCTCAGGGACCCCCTGGCCCTGCTGTGAGTGTCCCTGATGGGGAGATCTGGGGAGCAGAAAA GGGGAGACACCCTCAGCCCCTCGTCTCCTCGGCCTCCCCGTGACTGTAGTGTTCTCTCTGTGCAGGGTCC CGCTGGCGAGAGAGGTGAACAAGGCCCTGCTGGCTCCCCCGGATTCCAGGTGAGGCCTCATGGCTGTCAG GATGCTGGGAGGTAGGGGTAGGAAACACCTCTTTGGTCTCTTCCAGATTCTAAACCTTCCCTCCCTTCTT CCCCCATTTCCCACCTACAGGGTCTCCCTGGTCCTGCTGGTCCTCCAGGTGAAGCAGGCAAACCTGGTGA ACAGGTAAGAGGGAGCAGCCGGCCAGAGGGGTGGGAGATGCAGGGAATCCAGAGGGACAGGCCCCCGCTC CTAGCTAATCAGACAGCCATCAACTAGAGGGATTGAGGTTAGACGCCGGAAAGAACTTCCTCCCATGAAG GGAGCAGCACAGAGGGAAGTGGGGGCTGCATGATTGCTAGTCTGGGTGACTTCTTTTAAGAGCTGCTGGA ATATGCTGTGACTTTCCCTCAACCCTTCTATTGATAAATCTTGGTCCATAGTTTGGGGAGGGGGGAAGCC TTTGACACATCCCTAGGAGGAAGAGAGGGGCTGTTTGGGATAATCTCAATTCAGTGCTGAGAAGGGGTTC CTCTCTAATCACGGCCAGACCCCAGGAGGAAGGACCGTGCTTTCCAGCAGAGTGGCCCCAGGTGGGTTTT GCTCACTGTCTGTTCCTCTCTCCCTCCCCCTCAGGGTGTTCCTGGAGACCTTGGCGCCCCTGGCCCCTCT GGAGCAAGAGTAAGTAGGCCTCTCTCGCTGCATCCGTCAAGGTGCGTCGTACTTGGCCCTATCTCCAGAG CAGCCTTCACATGCCCTGTCCTTCCCTTCTAGGGCGAGAGAGGTTTCCCTGGCGAGCGTGGTGTGCAAGG TCCCCCTGGTCCTGCTGGTCCCCGAGGGGCCAACGGTGCTCCCGGCAACGATGGTGCTAAGGTGAGGGCA GCGTGGAAGGGGCTCTGGCAAGTGGCCCAGGGACCAGGTCTCACCCCTCCTGCAGCAGGGGATGGCGGGC CATGACCAAAGCCATGGAGATAGGGTGTGGGGTGGGGGGAAAAGACCAGGGCAGGGGCCCACACACAGCC TGGAGTCTGGGCTGTGAGTCTTTTCATCTTTTCTCAAGGCTTGTCGTTGGCCTTGGAAACAAGCCTGGGA GATACCAAGCGGGGCTTAGGGCTGTGACCCACTCTTGGGGCCCCAGGCCTCACTCCAGTCTTCTTGGTTG TCACATAGGGTGATGCTGGTGCCCCTGGAGCTCCCGGTAGCCAGGGCGCCCCTGGCCTTCAGGGAATGCC TGGTGAACGTGGTGCAGCTGGTCTTCCAGGGCCTAAGGGTGACAGAGTAAGTTCAACCTTCCCCCTCCCC TGAGCCCTACATGGCTCCCATCTCTGCCTGCTTTGAATCTCTCAGCATCTCTCCTTCTCTCTGGGATCTG TCCCTCTTCTCGCTAATCCTCCCTTCTTCCCCTTTCCCCTCTGGCCTTTTTGCTGATGAATCCTCTCCCT GTGGTCCAGGCCCATCTATCCCCATGGGTTACCATGGTGATGAGAGGTGGGGGCATCTCCTTGGTGGAGG CTCCCTTATTCATCCCGCTACACAAGTCAGGGGCCTCTTAACCTCAGTTCCACCTGAGTCTCCAGGCAGG CACCCTTTTTCCTGAAAGAATCTTTGAGTCCTTGGCCCAGGTGGAGGCAGGGCAGAGCTGCAGAGGGCCT CTCAGGAAACCCAGACACAAGCAGAACACTATAGGTCACCTCCTTGCCCCACACTGGAAATCTCAAGCTT ATCCATGTCTTTAGGGTGATGCTGGTCCCAAAGGTGCTGATGGCTCTCCTGGCAAAGATGGCGTCCGTGG TCTGACTGGCCCCATTGGTCCTCCTGGCCCTGCTGGTGCCCCTGGTGACAAGGTGAGGTGGCCGCCTCCC CACCTTCTGCCCTAACACATAGCCTCCTCAGCAGGCCTGGGCACGGTTCCGTGGGGTTGCGTTGGGAGAG CAGGTCCTGCCAAACTGAGCTGTCAACCTGGGAACCTGGAGGGACCAGAAGGAGGGGAGGCTCTCCTGGG GTCATCTACTAGGAGTATTCAGGGGAGGCCCTGACCCTGAGCCTCTTGTCCCTTGCTCTCAGGGTGAAAG TGGTCCCAGCGGCCCTGCTGGTCCCACTGGAGCTCGTGGTGCCCCCGTAAGTACAGAAGACCTGTTAAGA CCCCATACTTGGCCCTTCCCTCCCTTCACACAGCACCCCTGGCCCTGTCTGTGCCTTCACCCCTTGCCTC TCCCCTCACCGCATCCCCGCCTTCCCTCCTGTCAGCGCATCTCTCCAATCTGACTCCTTTTCTTCTAGGG AGACCGTGGTGAGCCTGGTCCCCCCGGCCCTGCTGGCTTTGCTGGCCCCCCTGTGAGTACCAAGACCCCC ATCATTTTTCATCACCGACTGGGACCTGGGACCTCGAGGGACGGAATGAGGACAAAGGCGTCAGCCATCC TCAGGGGAGAAGGGTGGAGACGGGATTGTTTCCCACCCAAGCATCTTCCTGCCTCCATTACTGCTCCTCC CCCAGGTAGTGGAAACTCCTGCCTCCTTCCCTCCATTCACCGCCCTGCTTCCTCCCCCAGGGTGCTGACG GCCAACCTGGTGCTAAAGGCGAACCTGGTGATGCTGGTGCTAAAGGCGATGCTGGTCCCCCTGGCCCTGC CGGACCCGCTGGACCCCCTGGCCCCATTGTGAGTGGCTTGGCCCTCTGTGCCCACGAGGCTGGTGGGCTG GGACCCAGGACGGGTCCAGGCTTGATGCCTCTGTGCTCTCCTACAGGGTAATGTTGGTGCTCCTGGAGCC AAAGGTGCTCGCGGCAGCGCTGGTCCCCCTGTGAGTATCACCCGCCTCTCTGTTGAGCCTCTCCCCTCTC CCCAGGCAGCGGTGGCAGGTGAGGGCAGCTGGGTCGGATGAGTTGGCTGTTCTCCCTCTGACTGTTCCTA TGTTCTCTCCTTCCAGGGTGCTACTGGTTTCCCTGGTGCTGCTGGCCGAGTCGGTCCTCCTGGCCCCTCT GTAAGTCTCTGCAGCAGAGTCCACTGCTCTAGGTTGGGGGTGCTGGGTGGGGGCTGCCAGAAGGATGGTG GGGCTGACTGAGGACCCAATGATGCACCAGAGCCCCCTGGAGTCTGACAGCCCCTCCTATCCTCATCCAG GGAAATGCTGGACCCCCTGGCCCTCCTGGTCCTGCTGGCAAAGAAGGCGGCAAAGGTCCCCGTGGTGAGA CTGGCCCTGCTGGACGTCCTGGTGAAGTTGGTCCCCCTGGTCCCCCTGGCCCTGCTGGCGAGAAAGGATC CCCTGGTGCTGATGGTCCTGCTGTAAGTGCCAGCTCAGATCTCTGCAGCTCCGGAGGTGTGCAGAGCTGG GGAGGGGTCCCTGTGCTGCTCTCTGGCACCTCACCCCTGTTTGCCTCCCAAAGGGTGCTCCTGGTACTCC CGGGCCTCAAGGTATTGCTGGACAGCGTGGTGTGGTCGGCCTGCCTGGTCAGAGAGGAGAGAGAGGCTTC CCTGGTCTTCCTGGCCCCTCTGTAAGTGCCCCCCTCACCTTGGGGGGCCCTGAGAAAAACCATCACAGGA CTTGGAGTGGGGCGGAGCCAAGGAGAACAGATTTGGTAGAGATGACTCCAGCGGACTCAAGGGTCCTCCC AGACCCTATCTCTGGCCTGACTCTTTCTTCTCCCTTAGGGTGAACCTGGCAAACAAGGTCCCTCTGGAGC AAGTGGTGAACGTGGTCCCCCTGGTCCCATGGGCCCCCCTGGATTGGCTGGACCCCCTGGTGAATCTGGA CGTGAGGTGAGCAGTCCCCAGCCCCCATGCCAGTACCCTCAGCATGGCCATTGTGGCCTTGCCTAAGCCC TCTTCCCCGGCTGACTCTCACTTCTCTCTCTCTCTCTCTGCAGGGGGCTCCTGGTGCCGAAGGTTCCCCT GGACGAGACGGTTCTCCTGGCGCCAAGGTAAGATGGCAACACTCCATGACCACAGCCTTGTCTGCTGCTT CCCTGCCCCATCCTGGCCCTTCACCCGGGGCTGACCCATATTCCCCTGCTCTCCCCGCCAGGGTGACCGT GGTGAGACCGGCCCCGCTGGACCCCCTGGTGCTCCTGGTGCTCCTGGTGCCCCTGGCCCCGTTGGCCCTG CTGGCAAGAGTGGTGATCGTGGTGAGACTGTAAGTAGCTGGGCTCCAGTTCCCTGTACCTGGTCAGGCCA GGGACTCTTCAGGCCTCCTTAGAGGCCTGGGGATGGGTGTCGGACTTCACCCAGGCAGGGGGAGGAAAGG AGATCCTGCAAGATGTCAGGGCCTTAATCCAAAAAACTGAGTTAAAGCTCAGCCCCAAGTCCCCTCTCCC AGACAGGACCGCCTCTCCCATGAGTTGGCCCCAGCTCCCGTGAAGATTGCAGTGGGGAGGTTTCCCTGGG AGTTGGGAGAGATGGCCACAGTGGGAAGCAGCTGAGGAGAGAGAGATCCAGCAGAGGGGAGGCCTCATCC TGCAGCCCCAGCCTCAGCCTTCCCTGGCCAAGAGCTCATGCTTTCCTTGCTCTCCCCAGGGTCCTGCTGG TCCCGCCGGTCCTGTCGGCCCTGTTGGCGCCCGTGGCCCCGCCGTAAGTACCCTGCTGTGTCCCCCATGC CTTTAGAACTCTACAGATGCAGACAGTGCCCCACTCGATGCCAATGGAACTTCCGCCTGACAGTTTGTCC CTTTCTCTCTTCTAGGGACCCCAAGGCCCCCGTGGTGACAAGGGTGAGACAGGCGAACAGGGCGACAGAG GCATAAAGGGTCACCGTGGCTTCTCTGGCCTCCAGGGTCCCCCTGGCCCTCCTGTAAGTATGCTCAGCCC CTCCCCAGTCCCCATGCTGTGCTGTGGGATAGGAGGGGGAGCTTCGCCTCAGTTTCCCCCTCTGGATAGT CATTCTTTCCCCTCCCTAGTGGGGACTGGGGTCTGAAGATTTGTGGGCATGTCCAAGTAGCTTCTGAGAG GGTGAGGGGTACACAGAGAGGGATTATGGGAGAGGTCTCTGCCTATGGACACCCTCGGGCTAGATTTCCA GAATAATGAAGGGGCATGGGTTGCCCACACTGCCCTTGTCTCTCCAGCCAGGCCCTCAGGCTACATTTGA CGCTCACTGGGCCTGAACTGCCTTTTTTATCTGTCCTTCAGGGCTCTCCTGGTGAACAAGGTCCCTCTGG AGCCTCTGGTCCTGCTGGTCCCCGAGTAAGTCATGCCTTCTCTCTCCTCTTCCTGAGCCCCAAGCCCAGG CTCACCTCGGGGACCCTTGCCAGGGACCCAGGCACCCTTTGCCTCTCTGGAGAAGGGTTCAGGGACAGGG AGTGGGCAAAGAGAGGAAGAATCCTGAACAAACAATCTGATCTAGCTTTGGCCTCTCTGCTCCCCAATCC GTCCTCCCCTGGCTCAGCGGCTGGGAGGAGCTATGGCATGTCCTATGGAAAGAGGCTGAGGCTGGCTCTA TGAGCCGTGGGGCCAGAGCCAGCAGGGAGGGTGGTGGGCCTCTCCTCCAGAGCTGGGGTTGTTCGGGCTT CTGGCAGCCTTTCTCAAACCATTTCCCCCACTCCAGGGTCCCCCTGGCTCTGCTGGTGCTCCTGGCAAAG ATGGACTCAACGGTCTCCCTGGCCCCATTGGGCCCCCTGGTCCTCGCGGTCGCACTGGTGATGCTGGTCC TGTTGTATGTAGCCCCTCATCCCCTCTGCTCATGGCCCTCCAGCCCCCAAAGCACTTGGATGCCGGTAAT CCCCACTCTCTTCCCTCTCTGTGCAGGGTCCCCCCGGCCCTCCTGGACCTCCTGGTCCCCCTGGTCCTCC CAGCGCTGGTTTCGACTTCAGCTTCCTGCCCCAGCCACCTCAAGAGAAGGCTCACGATGGTGGCCGCTAC TACCGGGCTGATGATGCCAATGTGGTTCGTGACCGTGACCTCGAGGTGGACACCACCCTCAAGAGCCTGA GCCAGCAGATCGAGAACATCCGGAGCCCAGAGGGCAGCCGCAAGAACCCCGCCCGCACCTGCCGTGACCT CAAGATGTGCCACTCTGACTGGAAGAGTGGTGAGGGCCTGCCCTAGCCTCTCCCTCCCTCCTACTCCTGC CATGCCAGGGTCCCCATGCCCATATGTGCCCCTACCATATGGTGCTGGCTGCTCCCTTTCCCTGACTCCA TCTTGCCCTGCCCTACCACAGGAGAGTACTGGATTGACCCCAACCAAGGCTGCAACCTGGATGCCATCAA AGTCTTCTGCAACATGGAGACTGGTGAGACCTGCGTGTACCCCACTCAGCCCAGTGTGGCCCAGAAGAAC TGGTACATCAGCAAGAACCCCAAGGACAAGAGGCATGTCTGGTTCGGCGAGAGCATGACCGATGGATTCC AGGTGCGTGAGCTGGACCTCAGAGCCAGTGTTAGGAGATGGGCTAGCCCAGTGCTCAGAAGGGACATGAA GTCCTGGAGTAGGTCTCTGCTAAGGGTGATGGACAGAGCTGGGCTGGGAGGCAGGGGTCTCAGGTCCCTG ATAGTGGTTCAGACACAGGCTGCCGATGGGCAGGTGGTGCCTCCTCTCGATATAACGGTGCATTGGGCAG CTCTCTGAGGACCCTGGACAGGGAGGCCAGGCAGGACTAGAGGTTCCCGCATAGCGGCTCACTCTTCCCT CTCTCCCCTCCCCTGCAGTTCGAGTATGGCGGCCAGGGCTCCGACCCTGCCGATGTGGCCATCCAGCTGA CCTTCCTGCGCCTGATGTCCACCGAGGCCTCCCAGAACATCACCTACCACTGCAAGAACAGCGTGGCCTA CATGGACCAGCAGACTGGCAACCTCAAGAAGGCCCTGCTCCTCCAGGGCTCCAACGAGATCGAGATCCGC GCCGAGGGCAACAGCCGCTTCACCTACAGCGTCACTGTCGATGGCTGCACGGTGAGTGCCCAGAATCCCC AGGCAGGGCCCCACCTCTCCGGCCTTGGGCTTTTTGGCCAGGCCATAGTGCCCTCTCTCCATCACTCCCA CGTGGTAATGCCCCCTCCCGTTGTCTCCGCCCCACCCCAGAGTCACACCGGAGCCTGGGGCAAGACAGTG ATTGAATACAAAACCACCAAGACCTCCCGCCTGCCCATCATCGATGTGGCCCCCTTGGACGTTGGTGCCC CAGACCAGGAATTCGGCTTCGACGTTGGCCCTGTCTGCTTCCTGTAAACTCCCTCCATCCCAACCTGGCT CCCTCCCACCCAACCAACTTTCCCCCCAACCCGGAAACAGACAAGCAACCCAAACTGAACCCCCTCAAAA GCCAAAAAATGGGAGACAATTTCACATGGACTTTGGAAAATATTTTTTTCCTTTGCATTCATCTCTCAAA CTTAGTTTTTATCTTTGACCAACCGAACATGACCAAAAACCAAAAGTGCATTCAACCTTACCAAAAAAAA AAAAAAAAAAAGAATAAATAAATAACTTTTTAAAAAAGGAAGCTTGGTCCACTTGCTTGAAGACCCATGC GGGGGTAAGTCCCTTTCTGCCCGTTGGGCTTATGAAACCCCAATGCTGCCCTTTCTGCTCCTTTCTCCAC ACCCCCCTTGGGGCCTCCCCTCCACTCCTTCCCAAATCTGTCTCCCCAGAAGACACAGGAAACAATGTAT TGTCTGCCCAGCAATCAAAGGCAATGCTCAAACACCCAAGTGGCCCCCACCCTCAGCCCGCTCCTGCCCG CCCAGCACCCCCAGGCCCTGGGGGACCTGGGGTTCTCAGACTGCCAAAGAAGCCTTGCCATCTGGCGCTC CCATGGCTCTTGCAACATCTCCCCTTCGTTTTTGAGGGGGTCATGCCGGGGGAGCCACCAGCCCCTCACT GGGTTCGGAGGAGAGTCAGGAAGGGCCACGACAAAGCAGAAACATCGGATTTGGGGAACGCGTGTCAATC CCTTGTGCCGCAGGGCTGGGCGGGAGAGACTGTTCTGTTCCTTGTGTAACTGTGTTGCTGAAAGACTACC TCGTTCTTGTCTTGATGTGTCACCGGGGCAACTGCCTGGGGGCGGGGATGGGGGCAGGGTGGAAGCGGCT CCCCATTTTATACCAAAGGTGCTACATCTATGTGATGGGTGGGGTGGGGAGGGAATCACTGGTGCTATAG AAATTGAGATGCCCCCCCAGGCCAGCAAATGTTCCTTTTTGTTCAAAGTCTATTTTTATTCCTTGATATT TTTCTTTTTTTTTTTTTTTTTTTGTGGATGGGGACTTGTGAATTTTTCTAAAGGTGCTATTTAACATGGG AGGAGAGCGTGTGCGGCTCCAGCCCAGCCCGCTGCTCACTTTCCACCCTCTCTCCACCTGCCTCTGGCTT CTCAGGCCTCTGCTCTCCGACCTCTCTCCTCTGAAACCCTCCTCCACAGCTGCAGCCCATCCTCCCGGCT CCCTCCTAGTCTGTCCTGCGTCCTCTGTCCCCGGGTTTCAGAGACAACTTCCCAAAGCACAAAGCAGTTT TTCCCCCTAGGGGTGGGAGGAAGCAAAAGACTCTGTACCTATTTTGTATGTGTATAATAATTTGAGATGT TTTTAATTATTTTGATTGCTGGAATAAAGCATGTGGAAATGACCCAAACATAA Download Select all
Length	17553
OMIM ID	120150
HGNC ID	HGNC:2197
Unigene ID	Hs.172928
Ensembl ID	ENSG00000108821
PharmGKB ID	-

mRNA Information

mRNA ID	XM_011524341.1
Exon	join(1..238,1702..1896,2059..2093,2196..2231,2322..2423, 3145..3216,3444..3488,3647..3700,3864..3917,4416..4469, 4586..4639,4979..5032,5121..5165,5282..5335,6171..6215, 6319..6417,6549..6602,6821..6928,7023..7076,7202..7300, 7466..7519,7608..7706,8602..8655,8799..8852,8956..9009, 9121..9174,9625..9669,9763..9861,10159..10266, 10725..10832,11053..11106,11269..11322,11541..11648, 11737..11790,11917..11970,12111..12272,12374..12481, 12639..12746,12854..12907,13012..13119,13500..13553, 13666..13773,14112..14165,14527..14634,14727..15009, 15142..15332,15629..15871,16001..17553)
mRNA Sequence	>1277 TCGTCGGAGCAGACGGGAGTTTCTCCTCGGGGTCGGAGCAGGAGGCACGCGGAGTGTGAGGCCA CGCATGAGCGGACGCTAACCCCCTCCCCAGCCACAAAGAGTCTACATGTCTAGGGTCTAGACAT GTTCAGCTTTGTGGACCTCCGGCTCCTGCTCCTCTTAGCGGCCACCGCCCTCCTGACGCACGGC CAAGAGGAAGGCCAAGTCGAGGGCCAAGACGAAGACATCCCACCAATCACCTGCGTACAGAACG GCCTCAGGTACCATGACCGAGACGTGTGGAAACCCGAGCCCTGCCGGATCTGCGTCTGCGACAA CGGCAAGGTGTTGTGCGATGACGTGATCTGTGACGAGACCAAGAACTGCCCCGGCGCCGAAGTC CCCGAGGGCGAGTGCTGTCCCGTCTGCCCCGACGGCTCAGAGTCACCCACCGACCAAGAAACCA CCGGCGTCGAGGGACCCAAGGGAGACACTGGCCCCCGAGGCCCAAGGGGACCCGCAGGCCCCCC TGGCCGAGATGGCATCCCTGGACAGCCTGGACTTCCCGGACCCCCCGGACCCCCCGGACCTCCC GGACCCCCTGGCCTCGGAGGAAACTTTGCTCCCCAGCTGTCTTATGGCTATGATGAGAAATCAA CCGGAGGAATTTCCGTGCCTGGCCCCATGGGTCCCTCTGGTCCTCGTGGTCTCCCTGGCCCCCC TGGTGCACCTGGTCCCCAAGGCTTCCAAGGTCCCCCTGGTGAGCCTGGCGAGCCTGGAGCTTCA GGTCCCATGGGTCCCCGAGGTCCCCCAGGTCCCCCTGGAAAGAATGGAGATGATGGGGAAGCTG GAAAACCTGGTCGTCCTGGTGAGCGTGGGCCTCCTGGGCCTCAGGGTGCTCGAGGATTGCCCGG AACAGCTGGCCTCCCTGGAATGAAGGGACACAGAGGTTTCAGTGGTTTGGATGGTGCCAAGGGA GATGCTGGTCCTGCTGGTCCTAAGGGTGAGCCTGGCAGCCCTGGTGAAAATGGAGCTCCTGGTC AGATGGGCCCCCGTGGCCTGCCTGGTGAGAGAGGTCGCCCTGGAGCCCCTGGCCCTGCTGGTGC TCGTGGAAATGATGGTGCTACTGGTGCTGCCGGGCCCCCTGGTCCCACCGGCCCCGCTGGTCCT CCTGGCTTCCCTGGTGCTGTTGGTGCTAAGGGTGAAGCTGGTCCCCAAGGGCCCCGAGGCTCTG AAGGTCCCCAGGGTGTGCGTGGTGAGCCTGGCCCCCCTGGCCCTGCTGGTGCTGCTGGCCCTGC TGGAAACCCTGGTGCTGATGGACAGCCTGGTGCTAAAGGTGCCAATGGTGCTCCTGGTATTGCT GGTGCTCCTGGCTTCCCTGGTGCCCGAGGCCCCTCTGGACCCCAGGGCCCCGGCGGCCCTCCTG GTCCCAAGGGTAACAGCGGTGAACCTGGTGCTCCTGGCAGCAAAGGAGACACTGGTGCTAAGGG AGAGCCTGGCCCTGTTGGTGTTCAAGGACCCCCTGGCCCTGCTGGAGAGGAAGGAAAGCGAGGA GCTCGAGGTGAACCCGGACCCACTGGCCTGCCCGGACCCCCTGGCGAGCGTGGTGGACCTGGTA GCCGTGGTTTCCCTGGCGCAGATGGTGTTGCTGGTCCCAAGGGTCCCGCTGGTGAACGTGGTTC TCCTGGCCCTGCTGGCCCCAAAGGATCTCCTGGTGAAGCTGGTCGTCCCGGTGAAGCTGGTCTG CCTGGTGCCAAGGGTCTGACTGGAAGCCCTGGCAGCCCTGGTCCTGATGGCAAAACTGGCCCCC CTGGTCCCGCCGGTCAAGATGGTCGCCCCGGACCCCCAGGCCCACCTGGTGCCCGTGGTCAGGC TGGTGTGATGGGATTCCCTGGACCTAAAGGTGCTGCTGGAGAGCCCGGCAAGGCTGGAGAGCGA GGTGTTCCCGGACCCCCTGGCGCTGTCGGTCCTGCTGGCAAAGATGGAGAGGCTGGAGCTCAGG GACCCCCTGGCCCTGCTGGTCCCGCTGGCGAGAGAGGTGAACAAGGCCCTGCTGGCTCCCCCGG ATTCCAGGGTCTCCCTGGTCCTGCTGGTCCTCCAGGTGAAGCAGGCAAACCTGGTGAACAGGGT GTTCCTGGAGACCTTGGCGCCCCTGGCCCCTCTGGAGCAAGAGGCGAGAGAGGTTTCCCTGGCG AGCGTGGTGTGCAAGGTCCCCCTGGTCCTGCTGGTCCCCGAGGGGCCAACGGTGCTCCCGGCAA CGATGGTGCTAAGGGTGATGCTGGTGCCCCTGGAGCTCCCGGTAGCCAGGGCGCCCCTGGCCTT CAGGGAATGCCTGGTGAACGTGGTGCAGCTGGTCTTCCAGGGCCTAAGGGTGACAGAGGTGATG CTGGTCCCAAAGGTGCTGATGGCTCTCCTGGCAAAGATGGCGTCCGTGGTCTGACTGGCCCCAT TGGTCCTCCTGGCCCTGCTGGTGCCCCTGGTGACAAGGGTGAAAGTGGTCCCAGCGGCCCTGCT GGTCCCACTGGAGCTCGTGGTGCCCCCGGAGACCGTGGTGAGCCTGGTCCCCCCGGCCCTGCTG GCTTTGCTGGCCCCCCTGGTGCTGACGGCCAACCTGGTGCTAAAGGCGAACCTGGTGATGCTGG TGCTAAAGGCGATGCTGGTCCCCCTGGCCCTGCCGGACCCGCTGGACCCCCTGGCCCCATTGGT AATGTTGGTGCTCCTGGAGCCAAAGGTGCTCGCGGCAGCGCTGGTCCCCCTGGTGCTACTGGTT TCCCTGGTGCTGCTGGCCGAGTCGGTCCTCCTGGCCCCTCTGGAAATGCTGGACCCCCTGGCCC TCCTGGTCCTGCTGGCAAAGAAGGCGGCAAAGGTCCCCGTGGTGAGACTGGCCCTGCTGGACGT CCTGGTGAAGTTGGTCCCCCTGGTCCCCCTGGCCCTGCTGGCGAGAAAGGATCCCCTGGTGCTG ATGGTCCTGCTGGTGCTCCTGGTACTCCCGGGCCTCAAGGTATTGCTGGACAGCGTGGTGTGGT CGGCCTGCCTGGTCAGAGAGGAGAGAGAGGCTTCCCTGGTCTTCCTGGCCCCTCTGGTGAACCT GGCAAACAAGGTCCCTCTGGAGCAAGTGGTGAACGTGGTCCCCCTGGTCCCATGGGCCCCCCTG GATTGGCTGGACCCCCTGGTGAATCTGGACGTGAGGGGGCTCCTGGTGCCGAAGGTTCCCCTGG ACGAGACGGTTCTCCTGGCGCCAAGGGTGACCGTGGTGAGACCGGCCCCGCTGGACCCCCTGGT GCTCCTGGTGCTCCTGGTGCCCCTGGCCCCGTTGGCCCTGCTGGCAAGAGTGGTGATCGTGGTG AGACTGGTCCTGCTGGTCCCGCCGGTCCTGTCGGCCCTGTTGGCGCCCGTGGCCCCGCCGGACC CCAAGGCCCCCGTGGTGACAAGGGTGAGACAGGCGAACAGGGCGACAGAGGCATAAAGGGTCAC CGTGGCTTCTCTGGCCTCCAGGGTCCCCCTGGCCCTCCTGGCTCTCCTGGTGAACAAGGTCCCT CTGGAGCCTCTGGTCCTGCTGGTCCCCGAGGTCCCCCTGGCTCTGCTGGTGCTCCTGGCAAAGA TGGACTCAACGGTCTCCCTGGCCCCATTGGGCCCCCTGGTCCTCGCGGTCGCACTGGTGATGCT GGTCCTGTTGGTCCCCCCGGCCCTCCTGGACCTCCTGGTCCCCCTGGTCCTCCCAGCGCTGGTT TCGACTTCAGCTTCCTGCCCCAGCCACCTCAAGAGAAGGCTCACGATGGTGGCCGCTACTACCG GGCTGATGATGCCAATGTGGTTCGTGACCGTGACCTCGAGGTGGACACCACCCTCAAGAGCCTG AGCCAGCAGATCGAGAACATCCGGAGCCCAGAGGGCAGCCGCAAGAACCCCGCCCGCACCTGCC GTGACCTCAAGATGTGCCACTCTGACTGGAAGAGTGGAGAGTACTGGATTGACCCCAACCAAGG CTGCAACCTGGATGCCATCAAAGTCTTCTGCAACATGGAGACTGGTGAGACCTGCGTGTACCCC ACTCAGCCCAGTGTGGCCCAGAAGAACTGGTACATCAGCAAGAACCCCAAGGACAAGAGGCATG TCTGGTTCGGCGAGAGCATGACCGATGGATTCCAGTTCGAGTATGGCGGCCAGGGCTCCGACCC TGCCGATGTGGCCATCCAGCTGACCTTCCTGCGCCTGATGTCCACCGAGGCCTCCCAGAACATC ACCTACCACTGCAAGAACAGCGTGGCCTACATGGACCAGCAGACTGGCAACCTCAAGAAGGCCC TGCTCCTCCAGGGCTCCAACGAGATCGAGATCCGCGCCGAGGGCAACAGCCGCTTCACCTACAG CGTCACTGTCGATGGCTGCACGAGTCACACCGGAGCCTGGGGCAAGACAGTGATTGAATACAAA ACCACCAAGACCTCCCGCCTGCCCATCATCGATGTGGCCCCCTTGGACGTTGGTGCCCCAGACC AGGAATTCGGCTTCGACGTTGGCCCTGTCTGCTTCCTGTAAACTCCCTCCATCCCAACCTGGCT CCCTCCCACCCAACCAACTTTCCCCCCAACCCGGAAACAGACAAGCAACCCAAACTGAACCCCC TCAAAAGCCAAAAAATGGGAGACAATTTCACATGGACTTTGGAAAATATTTTTTTCCTTTGCAT TCATCTCTCAAACTTAGTTTTTATCTTTGACCAACCGAACATGACCAAAAACCAAAAGTGCATT CAACCTTACCAAAAAAAAAAAAAAAAAAAGAATAAATAAATAACTTTTTAAAAAAGGAAGCTTG GTCCACTTGCTTGAAGACCCATGCGGGGGTAAGTCCCTTTCTGCCCGTTGGGCTTATGAAACCC CAATGCTGCCCTTTCTGCTCCTTTCTCCACACCCCCCTTGGGGCCTCCCCTCCACTCCTTCCCA AATCTGTCTCCCCAGAAGACACAGGAAACAATGTATTGTCTGCCCAGCAATCAAAGGCAATGCT CAAACACCCAAGTGGCCCCCACCCTCAGCCCGCTCCTGCCCGCCCAGCACCCCCAGGCCCTGGG GGACCTGGGGTTCTCAGACTGCCAAAGAAGCCTTGCCATCTGGCGCTCCCATGGCTCTTGCAAC ATCTCCCCTTCGTTTTTGAGGGGGTCATGCCGGGGGAGCCACCAGCCCCTCACTGGGTTCGGAG GAGAGTCAGGAAGGGCCACGACAAAGCAGAAACATCGGATTTGGGGAACGCGTGTCAATCCCTT GTGCCGCAGGGCTGGGCGGGAGAGACTGTTCTGTTCCTTGTGTAACTGTGTTGCTGAAAGACTA CCTCGTTCTTGTCTTGATGTGTCACCGGGGCAACTGCCTGGGGGCGGGGATGGGGGCAGGGTGG AAGCGGCTCCCCATTTTATACCAAAGGTGCTACATCTATGTGATGGGTGGGGTGGGGAGGGAAT CACTGGTGCTATAGAAATTGAGATGCCCCCCCAGGCCAGCAAATGTTCCTTTTTGTTCAAAGTC TATTTTTATTCCTTGATATTTTTCTTTTTTTTTTTTTTTTTTTGTGGATGGGGACTTGTGAATT TTTCTAAAGGTGCTATTTAACATGGGAGGAGAGCGTGTGCGGCTCCAGCCCAGCCCGCTGCTCA CTTTCCACCCTCTCTCCACCTGCCTCTGGCTTCTCAGGCCTCTGCTCTCCGACCTCTCTCCTCT GAAACCCTCCTCCACAGCTGCAGCCCATCCTCCCGGCTCCCTCCTAGTCTGTCCTGCGTCCTCT GTCCCCGGGTTTCAGAGACAACTTCCCAAAGCACAAAGCAGTTTTTCCCCCTAGGGGTGGGAGG AAGCAAAAGACTCTGTACCTATTTTGTATGTGTATAATAATTTGAGATGTTTTTAATTATTTTG ATTGCTGGAATAAAGCATGTGGAAATGACCCAAACATAA Download Select all
Length	5927

CDS Information

Location	join(136..238,1702..1896,2059..2093,2196..2231,2322..2423, 3145..3216,3444..3488,3647..3700,3864..3917,4416..4469, 4586..4639,4979..5032,5121..5165,5282..5335,8956..9009, 9121..9174,9625..9669,9763..9861,10159..10266, 10725..10832,11053..11106,11269..11322,11541..11648, 11737..11790,11917..11970,12111..12272,12374..12481, 12639..12746,12854..12907,13012..13119,13500..135
CDS Sequence	>lcl\|NM_000088.3_cds_NP_000079.2_1 [gene=COL1A1] [protein=collagen alpha-1(I) chain preproprotein] [protein_id=NP_000079.2] [location=127..4521] ATGTTCAGCTTTGTGGACCTCCGGCTCCTGCTCCTCTTAGCGGCCACCGCCCTCCTGACGCACGGCCAAG AGGAAGGCCAAGTCGAGGGCCAAGACGAAGACATCCCACCAATCACCTGCGTACAGAACGGCCTCAGGTA CCATGACCGAGACGTGTGGAAACCCGAGCCCTGCCGGATCTGCGTCTGCGACAACGGCAAGGTGTTGTGC GATGACGTGATCTGTGACGAGACCAAGAACTGCCCCGGCGCCGAAGTCCCCGAGGGCGAGTGCTGTCCCG TCTGCCCCGACGGCTCAGAGTCACCCACCGACCAAGAAACCACCGGCGTCGAGGGACCCAAGGGAGACAC TGGCCCCCGAGGCCCAAGGGGACCCGCAGGCCCCCCTGGCCGAGATGGCATCCCTGGACAGCCTGGACTT CCCGGACCCCCCGGACCCCCCGGACCTCCCGGACCCCCTGGCCTCGGAGGAAACTTTGCTCCCCAGCTGT CTTATGGCTATGATGAGAAATCAACCGGAGGAATTTCCGTGCCTGGCCCCATGGGTCCCTCTGGTCCTCG TGGTCTCCCTGGCCCCCCTGGTGCACCTGGTCCCCAAGGCTTCCAAGGTCCCCCTGGTGAGCCTGGCGAG CCTGGAGCTTCAGGTCCCATGGGTCCCCGAGGTCCCCCAGGTCCCCCTGGAAAGAATGGAGATGATGGGG AAGCTGGAAAACCTGGTCGTCCTGGTGAGCGTGGGCCTCCTGGGCCTCAGGGTGCTCGAGGATTGCCCGG AACAGCTGGCCTCCCTGGAATGAAGGGACACAGAGGTTTCAGTGGTTTGGATGGTGCCAAGGGAGATGCT GGTCCTGCTGGTCCTAAGGGTGAGCCTGGCAGCCCTGGTGAAAATGGAGCTCCTGGTCAGATGGGCCCCC GTGGCCTGCCTGGTGAGAGAGGTCGCCCTGGAGCCCCTGGCCCTGCTGGTGCTCGTGGAAATGATGGTGC TACTGGTGCTGCCGGGCCCCCTGGTCCCACCGGCCCCGCTGGTCCTCCTGGCTTCCCTGGTGCTGTTGGT GCTAAGGGTGAAGCTGGTCCCCAAGGGCCCCGAGGCTCTGAAGGTCCCCAGGGTGTGCGTGGTGAGCCTG GCCCCCCTGGCCCTGCTGGTGCTGCTGGCCCTGCTGGAAACCCTGGTGCTGATGGACAGCCTGGTGCTAA AGGTGCCAATGGTGCTCCTGGTATTGCTGGTGCTCCTGGCTTCCCTGGTGCCCGAGGCCCCTCTGGACCC CAGGGCCCCGGCGGCCCTCCTGGTCCCAAGGGTAACAGCGGTGAACCTGGTGCTCCTGGCAGCAAAGGAG ACACTGGTGCTAAGGGAGAGCCTGGCCCTGTTGGTGTTCAAGGACCCCCTGGCCCTGCTGGAGAGGAAGG AAAGCGAGGAGCTCGAGGTGAACCCGGACCCACTGGCCTGCCCGGACCCCCTGGCGAGCGTGGTGGACCT GGTAGCCGTGGTTTCCCTGGCGCAGATGGTGTTGCTGGTCCCAAGGGTCCCGCTGGTGAACGTGGTTCTC CTGGCCCTGCTGGCCCCAAAGGATCTCCTGGTGAAGCTGGTCGTCCCGGTGAAGCTGGTCTGCCTGGTGC CAAGGGTCTGACTGGAAGCCCTGGCAGCCCTGGTCCTGATGGCAAAACTGGCCCCCCTGGTCCCGCCGGT CAAGATGGTCGCCCCGGACCCCCAGGCCCACCTGGTGCCCGTGGTCAGGCTGGTGTGATGGGATTCCCTG GACCTAAAGGTGCTGCTGGAGAGCCCGGCAAGGCTGGAGAGCGAGGTGTTCCCGGACCCCCTGGCGCTGT CGGTCCTGCTGGCAAAGATGGAGAGGCTGGAGCTCAGGGACCCCCTGGCCCTGCTGGTCCCGCTGGCGAG AGAGGTGAACAAGGCCCTGCTGGCTCCCCCGGATTCCAGGGTCTCCCTGGTCCTGCTGGTCCTCCAGGTG AAGCAGGCAAACCTGGTGAACAGGGTGTTCCTGGAGACCTTGGCGCCCCTGGCCCCTCTGGAGCAAGAGG CGAGAGAGGTTTCCCTGGCGAGCGTGGTGTGCAAGGTCCCCCTGGTCCTGCTGGTCCCCGAGGGGCCAAC GGTGCTCCCGGCAACGATGGTGCTAAGGGTGATGCTGGTGCCCCTGGAGCTCCCGGTAGCCAGGGCGCCC CTGGCCTTCAGGGAATGCCTGGTGAACGTGGTGCAGCTGGTCTTCCAGGGCCTAAGGGTGACAGAGGTGA TGCTGGTCCCAAAGGTGCTGATGGCTCTCCTGGCAAAGATGGCGTCCGTGGTCTGACTGGCCCCATTGGT CCTCCTGGCCCTGCTGGTGCCCCTGGTGACAAGGGTGAAAGTGGTCCCAGCGGCCCTGCTGGTCCCACTG GAGCTCGTGGTGCCCCCGGAGACCGTGGTGAGCCTGGTCCCCCCGGCCCTGCTGGCTTTGCTGGCCCCCC TGGTGCTGACGGCCAACCTGGTGCTAAAGGCGAACCTGGTGATGCTGGTGCTAAAGGCGATGCTGGTCCC CCTGGCCCTGCCGGACCCGCTGGACCCCCTGGCCCCATTGGTAATGTTGGTGCTCCTGGAGCCAAAGGTG CTCGCGGCAGCGCTGGTCCCCCTGGTGCTACTGGTTTCCCTGGTGCTGCTGGCCGAGTCGGTCCTCCTGG CCCCTCTGGAAATGCTGGACCCCCTGGCCCTCCTGGTCCTGCTGGCAAAGAAGGCGGCAAAGGTCCCCGT GGTGAGACTGGCCCTGCTGGACGTCCTGGTGAAGTTGGTCCCCCTGGTCCCCCTGGCCCTGCTGGCGAGA AAGGATCCCCTGGTGCTGATGGTCCTGCTGGTGCTCCTGGTACTCCCGGGCCTCAAGGTATTGCTGGACA GCGTGGTGTGGTCGGCCTGCCTGGTCAGAGAGGAGAGAGAGGCTTCCCTGGTCTTCCTGGCCCCTCTGGT GAACCTGGCAAACAAGGTCCCTCTGGAGCAAGTGGTGAACGTGGTCCCCCTGGTCCCATGGGCCCCCCTG GATTGGCTGGACCCCCTGGTGAATCTGGACGTGAGGGGGCTCCTGGTGCCGAAGGTTCCCCTGGACGAGA CGGTTCTCCTGGCGCCAAGGGTGACCGTGGTGAGACCGGCCCCGCTGGACCCCCTGGTGCTCCTGGTGCT CCTGGTGCCCCTGGCCCCGTTGGCCCTGCTGGCAAGAGTGGTGATCGTGGTGAGACTGGTCCTGCTGGTC CCGCCGGTCCTGTCGGCCCTGTTGGCGCCCGTGGCCCCGCCGGACCCCAAGGCCCCCGTGGTGACAAGGG TGAGACAGGCGAACAGGGCGACAGAGGCATAAAGGGTCACCGTGGCTTCTCTGGCCTCCAGGGTCCCCCT GGCCCTCCTGGCTCTCCTGGTGAACAAGGTCCCTCTGGAGCCTCTGGTCCTGCTGGTCCCCGAGGTCCCC CTGGCTCTGCTGGTGCTCCTGGCAAAGATGGACTCAACGGTCTCCCTGGCCCCATTGGGCCCCCTGGTCC TCGCGGTCGCACTGGTGATGCTGGTCCTGTTGGTCCCCCCGGCCCTCCTGGACCTCCTGGTCCCCCTGGT CCTCCCAGCGCTGGTTTCGACTTCAGCTTCCTGCCCCAGCCACCTCAAGAGAAGGCTCACGATGGTGGCC GCTACTACCGGGCTGATGATGCCAATGTGGTTCGTGACCGTGACCTCGAGGTGGACACCACCCTCAAGAG CCTGAGCCAGCAGATCGAGAACATCCGGAGCCCAGAGGGCAGCCGCAAGAACCCCGCCCGCACCTGCCGT GACCTCAAGATGTGCCACTCTGACTGGAAGAGTGGAGAGTACTGGATTGACCCCAACCAAGGCTGCAACC TGGATGCCATCAAAGTCTTCTGCAACATGGAGACTGGTGAGACCTGCGTGTACCCCACTCAGCCCAGTGT GGCCCAGAAGAACTGGTACATCAGCAAGAACCCCAAGGACAAGAGGCATGTCTGGTTCGGCGAGAGCATG ACCGATGGATTCCAGTTCGAGTATGGCGGCCAGGGCTCCGACCCTGCCGATGTGGCCATCCAGCTGACCT TCCTGCGCCTGATGTCCACCGAGGCCTCCCAGAACATCACCTACCACTGCAAGAACAGCGTGGCCTACAT GGACCAGCAGACTGGCAACCTCAAGAAGGCCCTGCTCCTCCAGGGCTCCAACGAGATCGAGATCCGCGCC GAGGGCAACAGCCGCTTCACCTACAGCGTCACTGTCGATGGCTGCACGAGTCACACCGGAGCCTGGGGCA AGACAGTGATTGAATACAAAACCACCAAGACCTCCCGCCTGCCCATCATCGATGTGGCCCCCTTGGACGT TGGTGCCCCAGACCAGGAATTCGGCTTCGACGTTGGCCCTGTCTGCTTCCTGTAA Download Select all
CCDS ID	-

Protein Information

Protein ID	NP_000079.2
Protein Name	collagen, type I, alpha 1
Molecular Wt. (Da)	136514
Protein Sequence	>1277 MFSFVDLRLLLLLAATALLTHGQEEGQVEGQDEDIPPITCVQNGLRYHDRDVWKPEPCRICVCD NGKVLCDDVICDETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGP PGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGP PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLP GTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAG ARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGP AGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAK GEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERG SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQ AGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSP GFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPG NDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGP IGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDA GAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPG PPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGV VGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSP GRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAG PQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGK DGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYY RADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSGEYWIDPNQ GCNLDAIKVFCNMETGETCVYPTQPSVAQKNWYISKNPKDKRHVWFGESMTDGFQFEYGGQGSD PADVAIQLTFLRLMSTEASQNITYHCKNSVAYMDQQTGNLKKALLLQGSNEIEIRAEGNSRFTY SVTVDGCTSHTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAPDQEFGFDVGPVCFL Download Select all
Length	1464
Uniprot ID	P09341
Ensembl Protein ID	ENSP00000379110

Post-translational Modification Information (Source : HPRD)

Residue	Type	site
G	Proteolytic Cleavage	118
C	Proteolytic Cleavage	91
S	Phosphorylation	171
T	Phosphorylation	172
S	Phosphorylation	176

Enzyme Information

No matching records could be found.

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
960	CD44	115	NP_000601.3	in vitro	1730778
1294	COL7A1	358	NP_000085.1	in vitro	9169408

Pathway Information

Pathway Name	Pathway ID
AGE-RAGE signaling pathway in diabetic complications	hsa04933
Amoebiasis	hsa05146
ECM-receptor interaction	hsa04512
Focal adhesion	hsa04510
PI3K-Akt signaling pathway	hsa04151
Platelet activation	hsa04611
Protein digestion and absorption	hsa04974

Structure Information

PDB ID	1Q7D
Resolution	1.8
Method	X-RAY DIFFRACTION
Chains	A, B,
Molecule	collagen alfa 1(I) chain peptide GPOGPOGFOGERGPOGPOGPO
Model	View

Domain Information

ID	Location	Description
smart00038	1228-1464	COLFI
cl02436	1228-1464	COLFI superfamily
pfam01410	1245-1463	COLFI
pfam00093	40-95	VWC
cl17735	40-95	VWC superfamily
smart00214	40-95	VWC
pfam01391	236-295	Collagen
cl22949	236-295	Collagen superfamily
pfam01391	245-304	Collagen
pfam01391	701-759	Collagen
cl22949	701-759	Collagen superfamily
pfam01391	509-562	Collagen
cl22949	509-562	Collagen superfamily
pfam01391	497-549	Collagen
pfam01391	716-766	Collagen
pfam01391	272-324	Collagen
cl22949	272-324	Collagen superfamily
pfam01391	452-535	Collagen
cl22949	452-535	Collagen superfamily
pfam01391	527-595	Collagen
pfam01391	683-741	Collagen
smart00215	40-102	VWC_out
pfam01391	487-537	Collagen
pfam01391	668-725	Collagen
cl22949	668-725	Collagen superfamily
pfam01391	662-719	Collagen
pfam01391	536-607	Collagen
cl22949	536-607	Collagen superfamily
PRK07764	449-640	PRK07764
PRK07764	402-610	PRK07764
PRK07764	501-685	PRK07764
PRK07764	496-684	PRK07764
PRK07764	532-751	PRK07764
PRK12678	908-1111	PRK12678

Ontology Information

HPRD ID	708
Molecular Class	Extracellular matrix protein
Molecular Function	Glutathione transferase activity (GO:0004364)
Biological Process	Metabolism (GO:0008152); Energy pathways (GO:0006091)

SNP Information

View SNP Geneview Report

Drug Information

Uniprot ID DrugBank ID Name Type
P02452 DB00048 Collagenase clostridium histolyticum BiotechDrug

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO