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General Information



Gene_Symbol Gene_ID Gene_Name Chromosome Alias
CRTC1 23373 CREB regulated transcription coactivator 1  19KIAA0616, FLJ14027, TORC1 







  • Evidence
  • Gene
  • mRNA
  • CDS
  • Protein
  • PTM
  • Enzyme
  • PPi
  • Pathway
  • Structural
  • Domain
  • Ontology
  • SNP
  • Drug
  • External Links



Evidence Information


Pubmed ID Year Sample Information Techniques Mechanism Fold Change Remark
26300003   2015Cell line : -

Source : -

Sample Type : Mouse model

No. of Sample : -

Stage : -

-Up-regulation- CRTC1 as new mediator of PGE2 signaling, unravels the importance of its dysregulation in colon cancer and strengthens its use as a bona fide cancer marker.


Gene Details



NC_000019.9 (18794425..18893143)

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Gene Type protein coding
Gene Family -
Description -  
Chromosome 19
Location 19p13
Start 18794425  
End 18893143  
Strand +  
Gene Sequence

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Length 98719  
OMIM ID 607536   
HGNC ID HGNC:16062   
Unigene ID Hs.371096   
Ensembl ID -   
PharmGKB ID PA30730   

mRNA Information


mRNA ID ?NM_001098482.1
Exon  
mRNA Sequence

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Length  



CDS Information


   
Location
CDS Sequence

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CCDS ID CCDS32963.1



Protein Information


      
Protein IDNP_001091952.1
Protein NameCREB regulated transcription coactivator 1
Molecular Wt. (Da)0
Protein Sequence

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Length 634  
Uniprot IDQ9NZC7
Ensembl Protein ID ENSP00000348119  



Post-translational Modification Information (Source : HPRD)


Residue Type site
SPhosphorylation153;-
SPhosphorylation153;-
SPhosphorylation169;-

Enzyme Information


No matching records could be found.

PPi Information


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No matching records from HPRD source could be found.

Pathway Information


      
Pathway Name Pathway ID
HTLV-I infection hsa05166


Structure Information


No matching records could be found.

Domain Information




ID Location Description
pfam12885148-295  TORC_M
cl15143148-295  TORC_M superfamily
pfam12886559-634  TORC_C
cl15144559-634  TORC_C superfamily
pfam12884Jun-66  TORC_N
cl15142Jun-66  TORC_N superfamily
PHA03247211-475  PHA03247


Ontology Information


   
HPRD ID5949
Molecular ClassTranscription regulatory protein
Molecular FunctionDNA binding (GO:0003677)
Biological ProcessRegulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219)  



SNP Information


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Drug Information


No matching records could be found.

External Links


                                 
ArrayExpressGO
ICGCGO
Cancer3DGO
COSMICGO
NCGGO
TSGeneGO
Tumor Gene Family of DatabasesGO
CCDBGO
G2SBCGO
Osteosarcoma DatabaseGO
RCDBGO