Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CSPG4 | 1464 | chondroitin sulfate proteoglycan 4 | 15 | MCSPG, MEL-CSPG, MSK16, NG2, MCSP, HMW-MAA |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 18317448 | 2008 | Cell line : HT-29 5M21 and STD cell cultures Source : - Sample Type : - No. of Sample : - Stage : - | Proteome and DNA microarrays analysis,Production of recombinant TATI proteins | Up-regulation | - | - |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Proteoglycans / Cell surface : Other |
| Description | A human melanoma-associated chondroitin sulfate proteoglycan plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading on endothelial basement membranes. CSPG4 represents an integral membrane chondroitin sulfate proteoglycan expressed by human malignant melanoma cells. [provided by RefSeq, Jul 2008] | Chromosome | 15 |
| Location | 15q24.2 |
| Start | 75966663 |
| End | 76005189 |
| Strand | - |
| Gene Sequence | Download Select all |
| Length | 38527 |
| OMIM ID | 601172 |
| HGNC ID | HGNC:2466 |
| Unigene ID | Hs.513044 |
| Ensembl ID | ENSG00000173546 |
| PharmGKB ID | PA26963 |
mRNA Information
| mRNA ID | NM_001897.4 |
|---|---|
| Exon | join(1..181,19616..19779,22037..25573,27148..27630, 27937..28113,29808..30006,30108..30242,30390..30556, 34963..35146,35465..38527) | mRNA Sequence | Download Select all |
| Length | 8305 |
Protein Information
| Protein ID | NP_001888.2 |
|---|---|
| Protein Name | chondroitin sulfate proteoglycan 4 |
| Molecular Wt. (Da) | 247640 |
| Protein Sequence | Download Select all |
| Length | 2322 |
| Uniprot ID | Q16877 |
| Ensembl Protein ID | ENSP00000232375 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 712 | C1QA | 393 | NP_057075.1 | in vitro | 9013976 |
| 998 | CDC42 | 309 | NP_001782.1 | in vitro;in vivo | 10587647 |
| 5747 | PTK2 | 2859 | NP_005598.3 | in vitro;in vivo | 10587647 |
| 23426 | GRIP1 | 19086 | NP_066973.2 | in vivo;yeast 2-hybrid | 12458226 |
| 55729 | ATF7IP | 9811 | NP_060649.3 | yeast 2-hybrid | 15231748 |
| 80852 | GRIP2 | 18994 | NP_001073892.1 | in vivo;yeast 2-hybrid | 12458226 |
Pathway Information
No matching records could be found.
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00110 | 203-361 | LamG |
| cl22861 | 203-361 | LamG superfamily |
| cd00110 | 29-176 | LamG |
| cl22861 | 29-176 | LamG superfamily |
| smart00282 | 225-363 | LamG |
| pfam02210 | 232-363 | Laminin_G_2 |
| pfam00054 | 70-181 | Laminin_G_1 |
| smart00282 | 50-178 | LamG |
| pfam02210 | 72-178 | Laminin_G_2 |
| pfam00054 | 243-363 | Laminin_G_1 |
Ontology Information
| HPRD ID | 1391 |
|---|---|
| Molecular Class | Integral membrane protein |
| Molecular Function | Catalytic activity (GO:0003824) |
| Biological Process | Metabolism (GO:0008152); Energy pathways (GO:0006091) |
Drug Information
No matching records could be found.