Search results:
General Information
| Gene_Symbol | Gene_ID | Gene_Name | Chromosome | Alias |
|---|---|---|---|---|
| CX3CL1 | 6376 | chemokine (C-X3-C motif) ligand 1 | 16 | NTN, C3Xkine, ABCD-3, CXC3C, CXC3, fractalkine, neurotactin |
- Evidence
- Gene
- mRNA
- CDS
- Protein
- PTM
- Enzyme
- PPi
- Pathway
- Structural
- Domain
- Ontology
- SNP
- Drug
- External Links
Evidence Information
| Pubmed ID | Year | Sample Information | Techniques | Mechanism | Fold Change | Remark |
|---|---|---|---|---|---|---|
| 15586223 | 2005 | Cell line : - Source : - Sample Type : - No. of Sample : - Stage : - | - | Up-regulation | - | The expression level of Fractalkine was an essential biomarker for predicting the prognosis of patients with CRC. Fractalkine is considered to be one of the biomarkers for detecting patients with a high risk for recurrence, and who might therefore benefit from additional therapeutic strategies such as adjuvant therapy. |
Gene Details
| Gene Type | protein coding |
|---|---|
| Gene Family | Endogenous ligands |
| Description | - | Chromosome | 16 |
| Location | 16q13 |
| Start | 57372461 |
| End | 57385048 |
| Strand | + |
| Gene Sequence | Download Select all |
| Length | 12588 |
| OMIM ID | 601880 |
| HGNC ID | HGNC:10647 |
| Unigene ID | Hs.531668 |
| Ensembl ID | ENSG00000006210 |
| PharmGKB ID | - |
mRNA Information
| mRNA ID | NM_002996.4 |
|---|---|
| Exon | join(1..178,7174..7294,9570..12588) | mRNA Sequence | Download Select all |
| Length | 3217 |
CDS Information
| Location | join(109..178,7174..7294,9570..10572) |
|---|---|
| CDS Sequence | Download Select all |
| CCDS ID | CCDS10779.1 |
Protein Information
| Protein ID | NP_002987.1 |
|---|---|
| Protein Name | chemokine (C-X3-C motif) ligand 1 |
| Molecular Wt. (Da) | 39594 |
| Protein Sequence | Download Select all |
| Length | 397 |
| Uniprot ID | P05362 |
| Ensembl Protein ID | ENSP00000264832 |
Post-translational Modification Information (Source : HPRD)
No matching records could be found.
Enzyme Information
No matching records could be found.
PPi Information
(Click to view network : Source STRING) View
| Interactant Gene ID (Source: HPRD) | Gene Symbol | HPRD ID | Ref Seq ID | Technique | References |
|---|---|---|---|---|---|
| 1524 | CX3CR1 | 3277 | NP_001328.1 | in vitro;in vivo | 99 310 059 390 561 |
Pathway Information
| Pathway Name | Pathway ID |
|---|---|
| Chemokine signaling pathway | hsa04062 |
| Cytokine-cytokine receptor interaction | hsa04060 |
| TNF signaling pathway | hsa04668 |
Structure Information
No matching records could be found.
Domain Information
| ID | Location | Description |
|---|---|---|
| cd00274 | 25-100 | Chemokine_CX3C |
| cl00134 | 25-100 | Chemokine superfamily |
| smart00199 | 36-89 | SCY |
| cd00169 | 35-90 | Chemokine |
| cd00272 | 36-90 | Chemokine_CC |
| pfam00048 | 26-89 | IL8 |
| cd01119 | 50-90 | Chemokine_CC_DCCL |
| cd00271 | 40-95 | Chemokine_C |
| PRK14086 | 131-324 | dnaA |
| PRK10263 | 129-302 | PRK10263 |
| PHA03307 | 112-317 | PHA03307 |
| PRK07764 | 115-314 | PRK07764 |
| PRK12323 | 169-342 | PRK12323 |
| PHA03255 | 114-237 | PHA03255 |
| PHA03307 | 128-323 | PHA03307 |
| pfam05466 | 130-343 | BASP1 |
| PRK14954 | 189-303 | PRK14954 |
Ontology Information
| HPRD ID | 2664 |
|---|---|
| Molecular Class | Chemokine |
| Molecular Function | Transcription regulator activity (GO:0030528) |
| Biological Process | Regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolism (GO:0019219) |
Drug Information
No matching records could be found.