CoReCG

Search results:

General Information

Gene_Symbol	Gene_ID	Gene_Name	Chromosome	Alias
CYP3A4	1576	Cytochrome P450, family 3, subfamily A, polypeptide 4	7	HLP; CP33; CP34; CYP3A; NF-25; CYP3A3; P450C3; CYPIIIA3; CYPIIIA4; P450PCN1

Evidence
Gene
mRNA
CDS
Protein
PTM
Enzyme
PPi
Pathway
Structural
Domain
Ontology
SNP
Drug
External Links

Evidence Information

Pubmed ID	Year	Sample Information	Techniques	Mechanism	Fold Change	Remark
12625868	2003	Cell line : - Source : Department of Pathology of Wroc$aw Medical University. Sample Type : CRC tumor and Normal tissue No. of Sample : 17 Stage : TNM Stage I-III	Real time TaqMan RT-PCR	Unknown	-	-
12237780	2002	Cell line : Caco 2l, Caco 2 TC-7 and LS180 Source : - Sample Type : - No. of Sample : - Stage : -	Assay for CYP3A4 enzyme activity, Assay for paclitaxel metabolism and Analyses for mutations	Up-regulation	-	-

Gene Details

Chromosome: 7; NC_000007.13 (99354583..99381811, complement)
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Gene Type	protein coding
Gene Family	Cytochrome P450s
Description	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2011]
Chromosome	7
Location	7q21.1
Start	99756960
End	99784188
Strand	-
Gene Sequence	>gi\|568815591:c99784188-99756960 Homo sapiens chromosome 7, GRCh38.p2 Primary Assembly AATCACTGCTGTGCAGGGCAGGAAAGCTCCATGCACATAGCCCAGCAAAGAGCAACACAGAGCTGAAAGG AAGACTCAGAGGAGAGAGATAAGTAAGGAAAGTAGTGATGGCTCTCATCCCAGACTTGGCCATGGAAACC TGGCTTCTCCTGGCTGTCAGCCTGGTGCTCCTCTATCTGTGAGTAACTGTCCAGGCTCCTCTTCTCTGTT TCCTTGGACTTGGGGTGCTAATCAGGCCTCTCTTTCCCTTATCTGTTTTGAAGATCAAAAAAGATGTTCA GGCCGGGCGTGGTGGCTTACACCTGTAATCCCAGCACTTTGGGAGGCTAAGGCAAGTGGACTGCCTGAGG TCAGGAGTTCAAGACCAGCCTGGCTAACATGGTGAAACTCTGTCTCTACTAAAAATACAAAAATTAGCTG GGCATGGTGGTGCACGCCTGTATTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCGGC AGGCGGAGGTTGCAGTGAGCTGAGATCATGCCAGTGCACTTCAGCCTGGGTGACAGAGTGAGGCTGTCTC AAAAAAAAAAAAAAAAAAAAAAGATGTTCAAGGAGCAGTAGCTTAAGTGTTGGATGCTACAAACATATAG AGGTTATTGTAGATCTTATGCAGCTCTATAAAGGAATAAATAAGCATCTTCCCCATCCATCTTTAGTGGC AAGAAGGGTTTTGGGATAGCATTGATTGAGGATGATCTACTTGACAATAGTTTGGACCCAAGGAGGATAA GGAAGGAAAGTAGTGACGGATCTCATTCCAAACTTGGCTGTGGAAACCTGGCTTCTCCTTACTAAACTAG AATTTGGATTTTACATTTTCCCCTTTATGTTGCAGTAGAAGAGGATGAATCCTCTCACTGGTGGGATCCT GCCATCCTAGAGCAGGTAGAGAGAAGAGTCACTCCCCACTGTGGGTAGTGGAGGCTTCTCACATGTCACA TTTCACTTCTACCTCAATTTCACTCTTACTAAGATTTGGGAATCATAATGACAGGAAAATAGAAAATATA AACCTCATTTTAATTCTTTCACAGAAAGGTTAGAAATTCAGTGAGTTGTGGCAACATATTTTCCATCTTC TGACCTTTTAACACTAATTGATATGGCTTAAATTCATTCTATTTTAAACCAGATTTTTTTGGAGATAGTC TATTTCCAACATGTTCCTTCTAGGTGACAAATGAGGGCTGTTAGTTCAGTATTTGTTACAATAAATGTGT GTAAAATAACCTCACCTTTCCAGAATCATGTCAGGAATATGAATCTAATGCACAAATGTATAACTCTATG ACAAGATTGCATATATCTTTTAAAATATACCTTCCCAACGTTCATTTTAATACCCCTATTTCAAACAAAC CTGCTTAGCAGGTTATGTTAAACGCTCAGGGCAGAGGAGTAAGCAAGACTGTGAGCCAGTGATGACAGCA AAAGCATCCAGGTAGGATCAAAATGGAGTAAGAAAATATTCCTCATCCCTCAGGGTAGAACTCCAAAGAG ATATTCATGGGTCCTGGCCCCGTAGTGGAGGTCACTCAAAGGACAAACATGTTTGCATCTCATCTGCTTG AAGCCTGGACACAGAGGCACCATCTGTGTCACTCTGTGTGTGGTCTGCCATGTTGTGGGGTGGTCACTAC AGACTCAGGCAGCTGGGCAGACAATACCTTAGCCTTAGATGATGCTGATGCAGCCCAGGAGTCAGAAACT GTAGTGCAGACAATGCCCTCCTTAGGCCAACACAATTAAGTGCAATAGATGACTGGCTTTTCTGTTAGCC TCTTCATTGGAACCAAAAGCAGCATTACTCTACCAAACAGAGGGGAGCTGGAAAGAAACTACACAGTTTG CCCAGCCTAGCCTCTGCCTTGACACGGAACCATGTGAGTCTAGACATTCACCTAGATCATTCCTTGGGGA CCAATGCTGCTGACACATTAACTCAATAGTTTGTCCTGGCCTGAGAGGTCATGTAACTTGTAGAAAGTTT AGAAGCAGAGATTAGTGTCATTTATTTGCCATGGCTGTGACAACAAAGGAAGGAACAGGAGTGGGAAAAC CCAAGGCCACCCTGGTTTTGGTAGATGGTGCACACGCTTCCACTAACTGTTCTGGGGCAAAGATCCAAAT GCACTATTGGGCCTGGCTATGCTGCTTCTGCTGGGTCCCCCAAACATGAGCCTCCACGCCATTTCTCAGT TGTATTTTACCACATATTATCACAGTCACCGGATTTGTACAGAATATTTGGAACCTATACTGTCTTAAGG GCTACCCTTTAAAGAAGAGAAAACAAGGTTTTAATTCAACTGTCTGGAACATTTTATGTTTACTTATGTG GAATACTACATCTTTTGTTATAAACAGGAGGGAATGTGGACATTCGAAGGCCCCTACCTTTTAGCTAAAA GCCCATATGAAGCATATGGATCCATTTATACACACCATGCTTTTCAGCTACATTTTCCTAATTTGCCTCT CTGGGGCCAACCTTGTGGGACTAGCAGATTCATGGTTGAGTTGAAGGATGGTGACCTCTTCCATCAGCTT TTCTTCTTCCTCCAGTCTTCCAACCCTCAGTAACATCAGACTGGGAAGGTCTTCAGACATCCAGAAACCC CAGTTCGGGGAGTTCATACATGACCCATCAAAGATGAGTTGCAAGCAGGCCTGCCTTAGGGAGCACCAGC CTTAATGGGTTTTCCTACAGAGATAGTTGATGGGCAGATGCAATAAACTGACTGCTTTGTGATTGACCAC CTTGAGAAAAATTAGCATGTCTGGCTATGTTAGTCTTTTCTTGCATTGTTATAAAGAAATACCAGAGTCT GGGTATTTATAAAGAAAAGGGATTTAATTGTCTCATGGTTCTGCAGGCTGTACAGAAAGCATAGTGACTT CTTCCTCTAGGGAGGTCTCAGGAAATTTACAATCATGGCAGAAGGTGAAGGAGAAGCAGACAGATCTTAC ATGGCTGGAGCAGAAGCAAGAGAGGCTGGGGAGAAGGTGCCACACATTCAAACCACCAGATCTCATAAAA ACTCATTGTCACGAGGACAACACCTAAGGCGGGATGGTGTGAAACGATGAGAAACTGCCCCTAGGATCCA ATCATCTCCTACCAGGCCCCACCTCCAGTATTGGGGATTGCATTTCAACATGAGATTTTGGTAGGGGCAC AGATTCAGACCATATCACTGGCACTGTGCTAATCAGATGAATATCACCAGTTGGAAGGCTAGATTCCACA AGAGGAGGAATGACCTGGAAATTGGTTCTTTAGTTGTGATTCTTCTGCACACTGTCATTCAGGGAAATAT GAGTCAATCATCCTTCCCAATAGGTCAAATCAACCAGATCATCTGATCACAGAGACTGAGGTGTAGCTGA AAGCTGCTCACATTTCTATGAGGTCAATGGAAGCCTTGAGCACAGTTGTCAATCTGTAGAAATAAGGACT CTGTGACTCCTCCAAGACCTCTCTGTGAATGACGGTTTAAGAAGAACCAGATCCTAAAACAGGGTCAGAG CTTAGAGGGAAGGGAAAGCATAAAAGCCTCTGAGCAAATTCTAAAGACAGGGTCACCATAGGCTCTCAGT GACCCTCTGTGACTGAGTGGCTGCAGTGATGCAAAATCTCATCATCACTGCGGAAGACAAAAAAATGTCA CCCTTTCTACCTAGGATGAGAATCCCCAAATTTGGGGAGAGGCCACTTACTAAATAGACGTAAAGGAACA AAGTGACCTGGAAGAATTCCTGCCTGAACCTCTCAGGATCATTCACATTTGAGAACATTTATCAAATATT CATTCCAGGACTGGGACCATGAAGACTTCAGCTGCTTTGAGCTAATCATTGTAACTTTTTGGTGTCTCAT GGTGGAGGCAGGAAAGGACCTGATGAACAAATATAATCATTGCCGTCAGAGTTACTGTTATTATTTCTTG CCTTAATGTTACCTCGTTCTCTTGAGCATTCCAGTTCCTCAGTCAATGACTCATCAACCCCTATATCTAT AAAGTCACAATCGCTGTGACTTGATTTCTGTTTCACTTTGTAGATATGGAACCCATTCACATGGACTTTT TAAGAAGCTTGGAATTCCAGGGCCCACACCTCTGCCTTTTTTGGGAAATATTTTGTCCTACCATAAGGTG AGTGTTTTTGAGCTCACTCTTTTGCTTCTTATGATTGCCAAGAGCAGCTTAGTTCCATCAGTAAAAATGC TTCTCCTCAGGGGGAAGGTCTGAAGTTTTACACTTTCAGAAACAGTGTGTAGGCATCACCCAGAACATGG CAATGTTTACCCAAGGGCTCTCTTGCTAACTCTCAGGAACCTCAGGTTTGCCTCAGTTGAACAGCCCAAA TCTCAGGTAGATCAGCAACCTGATGCTCAGAACTTGATGTGCAAACTTTGTGAGCGCCATAAAGAAGGTT TTCTTTTTGCTCTATGCAGGTTCCCAGGAAGGTACAGTCATACTTAGTTAGTATTAAAAGTAGGAAAAGG ACCCCCTGATTGTGACTTGTTATCTGTGTACATGAGAGTCAAACTTTCCTCTCTGTAGCAAGAGCTCTTG AGTAGCCTTTTTTCCCTTCCTTCTGGACAGCTTTGAAACTCAATTTATTAGGGAGCCCAGGTATTTACCT TTGGGTCATTTGCACCTGCTTCAATCCTCTCCGAAAAATGCTAAATTCCCTGAGGGTATCTCCATGGCTC TACCCCAGCTCTTACTCCCCATGACATCTTTTGCAGCTTTGAGAGACAGAACAAAGGGGTTCTGCTTTAT TTCTTTTCCTTCAAAGGCTGCACCTTATGGGTGAGTCTGATCACAGACTGGATATAACTGAGATGAGACA GTGGTGGTCAATCAAACTCAGATATTTAAGCACAAAATGAGTTTGTGGGGTTTTTTTTTTACACAAAGGC GGAATCACATGCAAAATCACTAGAAAGGGGATGATTTGATGAAATTATTAAATATTTAATTTTGCTGAAT AGAATATAATATGTGCCACGTGGACCGTGAACTTTGGCCGAGCCTTTGTGCCTAACCTAGTCTGATGCTC TGCCCAGGGTCTGGGCCCTGGATGGAAAATTAGGAGCCCATGTCCACATGGCCAGCCGCAGCAGTCAGCT CTTTGGCTTACATCATCTTTCCCACATACCTGAGGCTTGTTTCTCAGATTCTAATTCTCTCAGGTGAGGG CTTTGTTGTCTAATTACTATCCAGGAATTTCATATTTTTTCCCTGTGCAAAAGCAATAATTTCCCCGCCA CCTTTTCCAGGTCAACTCTTTAGTAGATGTACCCCCAAGATGCACATTCCTGGGACCTTTGTTTGCACAG TTAAAATGTCACCCCTGAAATGTCGATACAGGAAGGTTTGTTTTTAAGTTTCAGTGAAAACTCTGAGCAA GTGTTGTAATTTGCTGTGTCCGATGTGTAGAGGGGACATTTTCTCAGAACTTCCATGTTAAGCTGGAAAA CTGGAAAGTGAGTTCACTTTGTCATTCTGTCACTCGTTCATTTTCTCACTCAACAACATGCCTCATACTT ACCTAAATCTGCTAGACTAAAGGAGTTCCCTGGTGTCTGTAACTTTCCAATTCTGCTAGAACTCTAGAGC GAGCTCATGAAATAAATGAAAAGGATGACAAAGAGATAAAACACTGTGCATTCTCTTCTGATGCTAATTC ACTTTCCCTTGGCCTCAGTTTCCCCATGTGCCCCTGGAGGTGATCATTCAGGGATTCATGAGATTTTCAA GACAACACATGAAAAAGCAAAAAGACATCAGAAAGACAAAGAGGTACTTAGTATTTATACACAAGGATAA GTCATTCAGTATCCACAACACTTGGAGAGAATTCAAGAGTGATTTTAAATTTCCCTTTTCAAATACCTCC TCTGTTTTCTCTTATTTCCTTTATGACGTCTCCAAATAAGCTTCCTCTAACTGCCAGCAAGTCTGATTTC ATTGGCTTCGACTGTTTTCATCCCAATTAGAGGCAGGGTTAAGTACATTAAAAATAATAATCAAATATTA TTTTGTTTCTCCTCCCAGGGCTTTTGTATGTTTGACATGGAATGTCATAAAAAGTATGGAAAAGTGTGGG GGTGAGTATTCTGGAAACTTCCATTGGATAGACTTGTTTCTATGATGAGTTTACCCCACTGCACAGAGGA CAGTCTCAGCCCAAAGCCTCTTGGGATGAAGCTCTTGTCAACCTAACTACAAACAGAGAGAAGTTCTCTG AAAGAAGAAGATATTTATTTGGGTGTAGAGTATTGCAATGGGAATCTGCATGCCTTTATAAACTATGTGC AAATTCAGGGAAGTAAAGCAAGACAAAGAGGCTCCAAGGAAAATATGAGGAGGATTTCTTATCAGTTTTG AAATAATTATCCTTCGCTACAAAGATCAGTAACAAGGGTGACGCCTCACCAAGGTTGGACAGGCAGTTGC TGGGCAGGTGTCCTTGCAGAAATATTTTTTTTAATGTTGGGATGGCCTTTGTGCAAGCTTGTAGTTTTGC GGAGTCTTTTGTGATAGTTTTGTTATCAGGCACACAAGCATGAGAATCCTCTCTTCATAGCCTTCTTTGA TTTATTTGTCAGGGTTTTTACACACACACACACACACACACACACACACACACACACACACAACTAGTGA CATCATTTTGGTTCTAACAACATTCACACTGGTTATTGTAAAACTTTTCGAAGGTTGTCCTACCAAGGAT CCCATGTGTCACCAGGTGTCAAGTTCTACAGTCTGAACTAGGCTGGGAGCATTGTGATTACTTTTCTCCA GACTTTGGTGGCCCAGGGACTCACAGCATCATGCTCTGTCCAGTGTCTGCCTATTCCCCTCTTCTTTTTT TTTTTCCTTAGGTGCCCTTTTATTACATGTGTTGTCTCAGACCCTTCTAATATGTGCTCATAAATACATC ATATCATCTCCTTCCCACATCAATTCACTTTCAATTAAAAGCCAAAACTCTTTCATTTAGACTTTGGATT TAAAGTGCTTTTGAATGAAGGGTTGAGAGATAATAGAGAAATAGATTGGCAAACCATTTATACTCTGCTG TTGTTGTTTTTTAATTTTATCTGCAAGTGTGGAACTTTTCATTCTGTTTTGTTATTAAATTTAAGCCAAG ACTTTTTAATAGAAGGGTATATAAGCATTTCTTTGTCTATACCTTCCTGCTGAATTTGAAGAAATGCTGA ATATTCTTAACCACTGGCGGGCTGATGGACTGTGATTTTATTTTATTTTTTATTTTTAGTTTTTTAAATT ATACTTTAAGTTCTGGGTTACATGCATAGAATGTGTAGTTTTGTTACATAGGTATACACGTGCCATGGTG GTTTGCTGCACCCATCAACCTGTCACCTACATTAGGTATTTCTCCTAATGCTATCTCTCCCCTAGCCCCC CACCCAACAACAGGCCCCAGTGTGTGATGTTTCCCTCCCCGTGTCCATGTGTTCTCATTGTTCAACTCCT ACTTAGGAGTGAGAACATGTGGTGTTGAGTTTTCTGATCTTGTGATAGTTTGCTGAGAATGATGGTTTCC AGCTTCATCCTTGTCCCTGCAAAGGACATGAACTCATTGTTTTTTTATGGCTGCATAGTATTCCATGGGG TATACGTGGCACATTTTCTTTATCCAGTCTGTCACTGATGGACATTTGGGTTGGTTCCAAGTCTTTGGTA TTGTGAATAGTTCTGCAATAAACATATGTGTGCATGTGTCTTTATCATAGAATGATTTATGCTTTGGGTA TATGCCCAGTAATGGGATTGCTGGGTCAAATGGTATTTCTAGTTCTAGATCCTTGAGGAATCACCACACT GTCTTCCACAATGGTTGAACTAATTTACACTCCCACCAACAGTGTAAAAGTGTTCCTATTTCTCCACATC CTCTCCAGCATCTGTTGTTTCCTGACTTTTTAATGATCACCATACTACCTGGCATGAGATGGTATCTCAT TGTGGTTTTGATTTGCATTTCTCTAATGACCAGTGATGATGAGCATTTTTTCACATGTCTGTTGGCTGCA TAGATGTCTTCTTTTGAGAAGTGTCTGTTCATATCCTTTGCCCATTTTTTGATGGGGTTGTTTGCTTTTT TTCTTGTAAATTTGTTTAAGTTCTTTGTAGATTCTGGATGTTAGCCCTTCGTCAGATGGATAGATTGCAA AAATTTTCTCCCATTCTGTAGGTTGCCTGTTTGCTCTGATGATAGTTTCTTTTGCTGTGTAGAAGCTCTT TAGTTTAATCATATCCCATTTGTCAATTTTGGCTTTTGTTGCCATTGCTTTTGGTGTTATATTTATGAAG CCTTTGCCCATGCCTGTGTCCTGAATGGTATTGCCCAGGTTTTCTTCTAGGATTTTTATGGTCCTAGGTC TTACATTTAAGTCTTTAATCCATCTTGAGTTAATTTTTGTATAAGGTGTAAGGAAGGGGTCCAGTTTCAA TTTTCTGCATATGGCTAGGCAGTTTCACCAACACCATTTATTAAATAGGAAATCTTTTCCCCATTGCTTT TGTGTGTCAGGTTTGTCAAACATCAGATGGTAGTAGATGCATGGTGTTATTTCTGAGGCCTCTGTTCTGT TCCATTGATCTATATTTCTGTTTTGGTACCTGTACCATGCTGTTTTGGTTACTGTAGCCTTTTAGTATAA TTTGAAGTCAGGTAGCGTGATGCCTCCAGTTTTGTTCTTTTTGCTTAGGATTGTCTTGTCTATGTGGGCT CTTTTTTGGTTCCATATGAACTTTAAAGTAGTTTTTTCCAATTCTATGAGGAAAGTCAGTGGTAGCTTGA TGGAAATAGCATTGAATCTATAAATTACCTTGGGCAGTATGGCCATTTTCATGATATGGAGTCTTCCTAC CCATGAGCATGGAATGTTCTTCCATTTGTTTGTGTCCTCTTTTATTTCATTGAGCAGCGGTTTGTAGTTC TCCTTGAAGAGGAGAACTTCACATCCCTTGTAAGCTGGATTCCTAGATATTTTATTCTCTTTGTAGTAAT TGTGAATGGGAGTTCACTCATGATTTGGCTCTCTGTTTGTCTATTATTGGTGTGTAGGAATGCTTGTGAT TTTTGTAAATTGATTTTGTATCCTGAGACTTTCCTGAAGTTGCTTATCAGCTTAAGGAGTTTTGGGGCTG AGACGATGGGGTTTCCTAAATATACAATCATGTCATCTGCAAACAGAGACAATTTGACTTCCTCTTTTCC TAATTGAATATCCATTTCTTTCTCTTGCCTGATTGCCCTATTCAGAACTTCCGACACTATGTTGAATAGG AGTGGTGAGAGAGGACATCCTTGTCTTGTGCCGGTTTTCAAAGGGAATGCTTCTAGTTTTTGCCCATTCA GTATGATATTGGCTGTGGGTTTGTCATAAATAGCTCTTACTATTTTGAGATACGTTCCATTGATACCTAG TTTATTCAGAGTTTTTAGCATGAAAGGCTGTTGAATTTTGTCAAAGGCCTTTTCTGCATCTATTGAGGTA ATTATGTGGTTTTTGTCATTGGTTCTGTTTATGTGATGGATTACATTTATTGATTTGGTATTTTGAACCC AGCCTTGCATCCCAGGGATGACGCTGACTTGATCCTGGTGGATAAGCTTTTTGATGTTTTGCTGGATTTG ATTTGCCAGTATTTTATTGAGGATTTTCGCATCGATATTCTTTAGGGATATTGGACTAAAATTCTCTTTT TTTGTTGTGTCTCTGTCAGGCTTTGGTATCAGGAGATACTGGCCTCATAAAATGAGTTAGGGAGGATTCC CTCCTTTTCTATTGTTCAGAAAAATTTCAGAAGGAATGATAACAGCTCCTCTTTGTATCTCTGGTAGAAT TCAGCTGTGAATCCATTTGGTCCTGGACTTTTTTTGGTTGGTAGCCTATTAATAATTGCCTCAATTCAAA ACCTATTATTGGTCTATTCAGAGATTCAACTTCTTCCTGGTTTAGTCTTGGGAGGGGGCATGTGTCCAGG AATTTATCTATTTCTTCTAGATTTTCTAGTTTATTTGCATAGAGGTGTTTATAGTATTCTCTGATGGTAA TTTGCATTTCTGTGGGATCAGTGGTGATATCCTTTTTATCATTATTTATTGCATCTATTTGATTCTTCTT TTTTCTTTATTAGTCTTGCTAGCAGTCTATCTATTTTGTTGACCTTTTTCAAAAAACCAGCTCCTGGATT CACTGATTTTTTGAAGGGTTTGTTGTGTCTCTATCTCCTTCTGTTCTGCTCTGATCTTAGTTATTTCTTG TCTCCTGCTAGCTTTTGAATTTGTTTACTCTTGCTTCTCTAGTTCTGTTAATTGTGATGTTACTGTGTCA ATTTTAGATCTTTCCTGCTTTCTCTAGTGGGCATTTAATGCTATAAATTTCCCTCTACACACTGCTTTAA ATGTGTCCCAGAGATTCTGGTACATTGTGCCTTTGTTCTCATTGGTTTCATAGAACATCTTTATTTCTGC CTTCACTTCCTTATTTACCCAGTAGTCATTCAGGAGCAAGTTGTTCAGTTTCCATGTAGTTGTGTGATTT TGAGTCACTTTCTTAATCATGAGTTGTAATTTGATTTCACTGTGGTCTGAGAGACAGTTTGTTGTGATTT CTTTTCTTTTACATTTGCTGAGGAGTATATTACTTCCAATTATGTGGTCAATTTTAGAATAAGTGCGATG TGGTGCTGAGAAGAATGTATATTCTGTTAATTTGGGGTGGAGATTTCTGTAGATGTCTATTAGGTCCTCT TGGTCCAGAGCTGAGTTCAAGTTCTGAATATCCTTGTTAATTTTCTGTCTTGTTGATCTGTCTAATATTG ACAGTGGGGTGTTAAAATCTCCCATTATTATTGTGTGGAAATCTTAGTCTCTTTGTAGGTCTCTAAGAAC TTGCTTTATGAATCTGGGTGCTCCTGTATTTGGGTGCATATATATTTAGGATATTTAGCTCTTCCTGTTG TATTGATCCCATCACCATTATGTAATGCCCATCTTTGTCTCTTTTGATCTTTGTTGGTTTAATATTCTTT TTAAAATAAAATATTTTAAACATATGAAACATTATGGAGAATGGCATGGGAAATATCCACGTATGCACCA CCCAGCTTAACAAATGCTCTACTGTCATTTCTAACCATGGTCTCTTTGAAGAGCTCTTTTGTCTTTCAAT GTCTCTTCCTTGTTTGGCCCACATTATCCTTCATCATATGAAGACTTGAGTGGCTCCTGTGTCAGACTCT TGCTGTGTGTCATACCTAATGAACTAGAACCTAAGATTACTGTGTATTGTACAACTAAGGGATTATGTAA AGTCAGGATCAAAGTCTGGCTTCCTGGGTTGGGCTCCAGCTGTAGAATAAGGCTGTTGATGTTTAATCAA CTCTGTTTTTTTCACACAGCTTTTATGATGGTCAACAGCCTGTGCTGGCTATCACAGATCCTGACATGAT CAAAACAGTGCTAGTGAAAGAATGTTATTCTGTCTTCACAAACCGGAGGGTAAGCATTCATGTGTTGAAA TTAAAATACTGATTGATTAAATTTATATTTTGAAATTCTTATATATTCATAGACAGTTGCCTAAAAAATG TCCAGGAAGGTTCCACGTCCACTTCATCCTGTCCCCCCCGAATGGTAACATCTTGCAATCTTGCATAACT ATAAATACAGTATATTCATGTTACTATATAGTACAGGAAATTGACATTGATACAGTTCACAGAGCTTATT CAGATTTCACCAGCTTTATGTGCCCTCATTTCTGTTCTATGCAAATTTATCACAATCATAGATTTGTGCA ATGACCAGCATGATCAAAACGCAGAACCCATTTGTGTTCTATACAAATTTATCACATCATTAGTAGATTT GTGCAATGACCAGCATGATCAAGATGCAGATCCACTCTGTCTCCATGTGGCTCCCTCCTGCTATCCTACA GTCACAAGTCTTTTTCTCTGACAGGGTCCATATCAGAGCAAACTATTTTTTATTTTGAGGTGATCAATGT ATTAATATTTCCTTTTCTGGATTGTACTTTTGGTGCCATGTTTGAAAGTTCTTTGCCTAGCCCTCCTTCC TATATTGCTGTTTTTTTCTAAAAGTCATAAAGTTTAATGCTTTACTAAATGTAGCTCTATTATCAATTTT GTGTTATTTTTTGTATAAGGTATGAGATTTAGATCAAGGTTCATTTTTTTTGTGGCTTATGGCTGTCCAA TTCCTCCAACGCCATTTTTGGAAAGATGGGTATATTGTTAAAAATCAACTGGGCATACTTCTTTGCATCT CTCACGTACTACTGTGTCCCATTGATCACTGTGTTTATTATTCCACCAATACCACACTGTGTTGACCCTA GTAGCTGTACACTAACTCTTAACCTCGTGTAGAGTGATTCTTCCCACTTTTATTGACTTATTTTTTCAGA TTTGTTTTAACTCTTCCTGGTCCTCTGCTTTTCCATAAAAATTCAGAATGAGTTTCTCAGTGTCTACAAA TAAACGTGCTGTTATTTTGACAAGAATTGAATTAAATATATAGACCAGTTTATGGAAAATGTGTATCTTT ACTGTTTGATCTTTCAATTCATGAACATAGTATGCCTCTCCATTTCCTTAGATTTTCTTTGATTGCTTTT AACATCTTGTAGTTTTCAGCATAGAGATCCTGTACATGTTTTGTTAGATTTACAGCTAAATTATTTCATT TTTGTTGGAATGACTGTAAATGATATTATGTTTTTCTTGTATTTTCAGATATTGATTGTTGTTACATAGA AATGTGCTTTGATTTTGTGTGTTGATCTGGTATCCTAGAACCTTGCAGAACTGACATAGTAGTTCTAGAA GTCTCTTTGTATATGCCTTGAGATTTTACACATTGTCAGTTATGTCACTTGAAAATAGAGACAATTCTTT TATTTCCTTTCCAATCTGTATGCCTTTTATTTCTTTTCTTTTGTCTATTGCACTAGGACTTCCCAGTATA ATGTTGAGTAAATGTGGTGAATTTTTGAATTGTTCCTAATCTTAGGAGGGAAGCCTTCAGTTCTTTCATC ATTAAGCATCATTTAGATGAAGTGGGCTGTTTTTTTGTAGATTCTCTTTATCAAATTGAGGAATTTTCTC TCCCTAGTTTGCTGAGTTTTTATCATAAATGAATGCTGGAAGTACTCATTATAAAAAAAATGGCTATGGA AGATGAAAGAAAGTTTCAAGCATGTTGGCTTGATAGGCCAGTTCCAAGTTGGCAAAAATAATTATCTCTT TTTTCTTTCTATCCATGAAATAAAAAATTAAGAGACAAGAATGTTTATGGAATTGCATTATTTCTTCAAA ATATGTTCCTAGTTTTAAAGGTATTACCTACTATTTTTTTTAAAACCATCACATTGAGGCACTTCTTTTT CACGTTGCCCATGCTGCAGGAGAACATAAAGACAGCTTGTCTGAGGCAACATACAATCCACCAAAGTCAC CTGCTTGTCTGTCTCCACTCCGTCTCTACACTGCAGAAGTGCTAGGTCTTGATTCTGTTTATTGTACTGG AAGAACACATTCTCTACCACGTGGATAATTTGCATGTAAAAGAAGACTGGGATATAGAGGCTGGAGACGA CATCAGGGTCTCCTGAACACTGCCGCCACCCCCCCGCCCCGCCCCACACAAATACATCCCAGGACACTGG GCATCTGGGATAAATCTCTATTGAGCATCTAGCATAGGGCCCATCACCCAGTAGACAGTCACTAAATAGT TGTTGAATAAGTGTTCCTGTTTAACACATTTTCTACAACCATGGAGACCTCCACAACTGATGTAGGACAA AATGTTTCTGCTTTGAACTCTAGCCTTTTGGTCCAGTGGGATTTATGAAAAGTGCCATCTCTATAGCTGA GGATGAAGAATGGAAGAGATTACGATCATTGCTGTCTCCAACCTTCACCAGTGGAAAACTCAAGGAGGTA TGAAAATAACATGAGTTTTAATAAGAAACTTAAAGAATGAATCTGGTGGGGACAGGTATAAAATAAGATC ACAGTCCCTTTCCAAGGGGTAGTCCACTGAATTTGAGCTGCCTAAAAATGGTCTTTTATCTTTATGTACA GAAAACACATCACAAAATTCATTATAAAATGTCACTTACTGCTCCATGCTGGGGAAAGCCATGTCCTTCT GGGACTAGAGTCTGCACATTTAACTATGGGTGGTGTTGTGTTTTGTGCTTAGATGGTCCCTATCATTGCC CAGTATGGAGATGTGTTGGTGAGAAATCTGAGGCGGGAAGCAGAGACAGGCAAGCCTGTCACCTTGAAAG AGTAAGTAGAAGCGCAGCCATGGGGTTCTGAGCTGTCATGAACCCCTCCAGCTGCCTGCCATGGAGCTGA TATTCCTGCTGTTGGGTTATTCCAGTGACCAGACAAAAGGAGGGCTGTGGTAATGCAACTTCAATGGGTC TCCCAAGATGGGGCAGCTCCGATGAGGAGGTGGGGCAGCTGGAGGAAAAGGATCTTCTCCCCTGTGCACA GGGGCCAGGGTTTACATATCCATTAAATTGTCACCTTGGATATTCTAGAAGACTAAATATATCCTTTAGG GGGAAAAAGTGTGATTGTACCAAAGTTTTAAGCATGGAGTGTATGGGATGGTGGAAGGGGAAGGCACTTG GTATCTGTTGGTTGGCAGTGAGTAGGTTGGGAGAGTTATAATGGAGAACTTAGAATAACTTTGATCATTT CATGTTTTTTTCTGAGGATATCAGTAGAATACTAAATATTAAAATTCCTACCATTTCTTTTTCCTCCAGT CTCAAAGAGAGAGGGTGGTAAAAACACTATAGGTAGGGCAAGCCTATTATTTGCTATCTACACTTATGCA GTAAAAACAGGTGTAATCTGAGTTTGTCCTGGGCAGACCAGGGATATGTGGTCACTCACTATAGAAATTT CCAAATCAAATTTTGAGAGATTTTTTTTTAACCAGGACATTATTGGTCATTATATTTTACAAAAATAATT CTGCTGTCAGGGCAACCTCAGCTCACCACAGCTGGGGATAGTGGAATTTTCCAAAGCTTGAGCAGGGAGT ATAGAGAATAAGGATGATATTTCTAGGAGCTCAGAACAGGGTACTGTTGCTTTGTAAAGTGCTGAAGAGG AATCGGCTCTGGGCATAGAGTCTGCAGTCAGGCAATATCACCTGTCTTGAGCCCCTTAGGAAGAGTTAAT TATTCTACTCTTGTTCTGCTGAAGCACAGTGCTTACCCATCTTGTATCATCCACAATCAATACATGCTAC TGTAGTTGTCTGATAGTGGGTCTCTGTCTTCCTATGATGGGCTCCTTGATCTCAGAGGTAGGTCTAATTC AGTTCAGTGTCTCCATCACACCCAGCGTAGGGCCAGCTGCATCACTGGCACCTGATAACACCTTCTGATG GAGTGTGATAGAAGGTGATCTAGTAGATCTGAAAGTCTGTGGCTGTTTGTCTGTCTTGACTGGACATGTG GGTTTCCTGTTGCATGCATAGAGGAAGGATGGTAAAAAGGTGCTGATTTTAATTTTCCACATCTTTCTCC ACTCAGCGTCTTTGGGGCCTACAGCATGGATGTGATCACTAGCACATCATTTGGAGTGAACATCGACTCT CTCAACAATCCACAAGACCCCTTTGTGGAAAACACCAAGAAGCTTTTAAGATTTGATTTTTTGGATCCAT TCTTTCTCTCAATAAGTATGTGGACTACTATTTCCTTTTATTTATCTTGCTCTCTTAAAAATAACTGCTT TATTGAGATATAAATCACCATGTAATTCATCCACTTAAAATATACAGTTCAGTGATTTGTAGTACATTTG AAGATATGTGTGACCATCATCATTTTAAACTTTAAAACTTTTTTTGTCAATCTAGAGACCTCATACATTT TTAGCTATCAGCCCCCTGTCACAAACCCTGTCATCATATGCAACCACTAATCAACTTTCTGCTTCTATGG ATTTGCCTATTCTGGACACTTCATAGAAATGATATTAATTCATCAGGGTTTTTTATTCTCTAGTTCATGA ATTTGTACTTTAGTCTGTATCATTTTCTTTCTTCTGCTGGCTTCAGGCTTAGTTTGCCCTTCTTCGTTTA CTATGTTGTGGCATGAACATAGATTACTGATTTGTGATTTTTTTGTTCCTCTAAATTTAGACATTACAGC TGTAACTTTCCCTCTGAGCACTTCCTTTGCTAAATCCCATGAGATTGTGGTCTATCACATCTTAGTTTTT GTTCACCTCAAAACAGTTTCTATTTGCCCTTTTGGTTTCTACTTTGACTCATTGGTTACTTAAATGTTTA TTATTTAACTTCCACATATGTGTGAGTTTCTCAATTTTCTTTCCCTTATTGATTTTATCTTTATTCCATG ATAGGTGACAGAGATATGCTGTGTTATTTCTATCTTGACTACCTACTATTTCTTGAACAGCAAGATTAAT TTTGAGCTTCAGATTATGATTTGGGTTATTCTAGGAGACTGTAGTCCAATAGATAAAGGCAAAGAGATTA GGGCATTGAATTTTGTTCCTTTTATCCTTCAAAAGATGCACAAGGGGCTGCTGATCTCACTGCTGTAGCG GTGCTCCTTATGCATAGACCTGCCCTTGCTCAGCCACTGGCCTGAAAGAGGGGCAAAAGTCATAGAAGGA ATGGCTTCCAGTTGAGAACCTTGATGTCTTTTACTCTTCTGGTTGGTAGAGAAAACTAGAATTGCTCCAG GTAAATTTTGCACATTCACAATGAATTTCTTTTTCTGTTTTTGTTTTGTTTTTCCTACAGCAGTCTTTCC ATTCCTCATCCCAATTCTTGAAGTATTAAATATCTGTGTGTTTCCAAGAGAAGTTACAAATTTTTTAAGA AAATCTGTAAAAAGGATGAAAGAAAGTCGCCTCGAAGATACACAAAAGGTAAAATGTGGTGGTAGTTATA GGAGGATGTTTAGTTTTTCATAATTTTTTAGATAATATACATATGATCAGTGCAGTTACCTGTATGTTTT TAAAGAATGCTTTTAACATGAAGACTGCTCATGTTTAGAGCAAGAGAATTCATTTGGTAGAAATGCAGAA AGTGGGGTTTGGGGAAGGAGATATGAGAATGAGTCAGAGACAGCACATGAAATTTGATATCAGACACAAC AATTAGTATGCCACGGCATAAATTTTATTGAGATAAAACTTTACCACTTTACTTCCCTTCAATAAATTGT CAGAGGATAAACATTACTGTTTGGAAATATATTTTACTGATATTATGCTTTCCCCAGATCATAAATTGGT AAAGACTCATTTCAAGTACAAACCTGTTATTTTACACATTCTCAAATGAAAGTCCCTATCAGGCCACCTG CTGAAGTGTAGCGTGTGTTAAATTTGAGCCATCTCACATGATAGCCAGATTTGTTTCAGGAAAACATCCT GCTTTCCAAGGATTTAGAAGGGTATGTTTTTCACTGGTGATTCAGGCAACATGCATCAGATTTCTGGTCT TCAAGGAGCCATATTCTCAGAAGGGAGATCAAGGACCACGCTTGTGATTTACTTCTGACTTCAGGAGCCA CTTTCTGTCAGTGAAATTTCTCTTTTTGCTTCTAGCACCGAGTGGATTTCCTTCAGCTGATGATTGACTC TCAGAATTCAAAAGAAACTGAGTCCCACAAAGGTAACCAGAGTGTTTCTGAGGGCTACTTGTGGGGCACT CAGAGGGAAGGCCTTGTTCTGAAAATGTGCAGGAAGTATTCCAGGATGATGAGAATTTCTGCCACATAGC AGAACGACACATGTTTGAATGTTATAAGTGGTAGTTGGAGGCACTTTCTAGAGGCATGCAGGCATAGATA GCCATGTTCTAAGAGTAAAGGGCAACCCTAAGCAAACCTGGCATGCTAGAAAGTCAGTCTGCGGTCTGTG GATCACCTACATCAGATCAAATGCCAATTCTCAGCCTCCTTCAGATCCACTGAATAAAAATTTCTGCCTA GAAATTTATTAGGTTGCTGCAAAATTAATTGTGGGTTTTTCCATTACTTTTAATTGCAAAAAAATGCAAT TAAAAGTAATGGCAAAAACCACAATAACTTTTGCAGCTACCTAATACATCTAACATCCAATCAGGAGCCA CGCTGTTCCAAAAGGGGTGATTTTAACTGGCAGTACTTGTTGAAAGTGTGTTCACCAGGTTAATCTACTG CAAAGTTATTTTCCACTTTGGAATGGATTAGTAACTTGTGGGGAAAACCTCTGAGACCGTGTAAATATCC TCTTTGTCTTCAATGTTTCACCTACGAGTTTTACAACCCATGTATGTTTTTTACTGAAGTCACTATTACT ATGACAGTGGCAAAATGATGACCATGGTCAATTACAAGCCACCAAGACTTGGCAACCATCTCACAAAATT CCTGAATATTTAACTATTGGTTCTAGAGAGCAGGACTGGGCTTACTCCAGCATACTGCTTTAAATATATC CATGTCTACATCCACTTTTGTCTGTATGTCTATGTATCTATCTATGTATCTATCTAGCTATGTATCTATC TATCTATCTATCATCTATCTATCTATCATCTATCCATCTATCATCTATCATTTATCCATCTATCATCTAT CTACTTATATATTATCTATCTATCATCTAACTATTCATCTATCTATCCCAATATAACTTGCTGTGATAAA GGAAATAGTCTATTGTTTTACTGTTTCATATAGAAATCACTAGACACATATGGCTATTGAGCACTGGATA TGTGGCTAGTGCCATTGAAGATCAATTTTAAATGGTATTTCAGTTTAATTTAATAAAATTTGATTTTAAA TAGCCACTAGTGGGTAGTGGCTACCATATTGGACAGCAGAGCTCTAAACTTTGAGATTATAGTTCAATTT CACATCAGTATCATCAGGTTCATGATAACTGAATACTATGATTAGGTAGTTGAATTTACTTATAACTGCA TCACAGAAGTCTTCACTGGTAAATCACAGCTCTGTCGACCTTTCTCACACTCCTTTCATATTGGTTTTGG TTGTGAATTACATGGTTGGAGCAGGCATTATATTTATTTCTATGTTCCAGGTCTCTAAAGGTCCTAATCC AGTCCTGATCAAACAGACCAGTGATGGACCATCCTGAGCTTCTCTCAGGAGAAAAATCAAGAGGGGCCCA ACTTGTAATCATAGGAGCTTATGCTATTTTAATGCCATCCATCAGACTACAATCAATTACCACTCATCTA GCTTTTTGTCCATCTCTCATTCTTGTACATCCTGAGATAGTCAATTCTGAGAACTGTAGCCTAGATCTAT CACCTGATGCCTCTCAAAGATATAATCCGTGCTTCTCAAGCTAGGCTATGCACACAAATCACTGCATCTT GTGAAAGTTCAGATTTTGAATCAGTAGTTCAAGGGTGGGGTTTGAGATTTTGCATTTCTAATGAGCTCTC AGATGCTTCTGACCCATGGACCACACTTTGAATACCAAGAAGTGGTCTGTAGACCAATATTGGTCCCTTA AGTTCCCTCAAACATATCTTCGGGAAACGTCCTTTGATTTTCCCTACATTTAACCATTAGTGTTGCAAAT TCTCTCAAAGTTTGTCAAGATATATTGTAGCTAAAATAAATTACATTTTTCTTGGGGGAGAGTACTACCT CATATTAACTTACAATAAAGTACTTTTAGGATCATTCAAGGAACACACCCATAACACTGAGTATGTTATG CGGAAATGCTCTCTCTGGAAATTACACAGCTGTGCAGGTGGCGGGGGTGGCATGAGGAGGAGTGGATGGC CCACATTCTCGAAGACCTTGGGGAAAACTGGATTAAAATGATTTGCCTTATTCTGGTTCTGTAAGATACA CATCAGAATGAAACCACCCCCAGTGTACCTCTGAATTGCTTTTCTATTCTTTTCCCTTAGGGATTTGAGG GCTTCACTTAGATTTCTCTTCATCTAAACTGTGATGCCCTACATTGATCTGATTTACCTAAAATGTCTTT CCTCTCCTTTCAGCTCTGTCCGATCTGGAGCTCGTGGCCCAATCAATTATCTTTATTTTTGCTGGCTATG AAACCACGAGCAGTGTTCTCTCCTTCATTATGTATGAACTGGCCACTCACCCTGATGTCCAGCAGAAACT GCAGGAGGAAATTGATGCAGTTTTACCCAATAAGGTGAGTGGATGGTACATGGAGAAGGAGGGAGGAGGT GAAACCTTAGCAAAAATGCCTCCTCACCACTTCCCAGGAGAATTTTTATAAAAAGCATAATCACTGATTC TTTCACTGACTCTATGTAGGAAGGCTCTGAAAAGAAAAAGAAAGAAACATAGCAAATGGTTGCTACTGGC AGAAGCGTAAGATCTTTGTAAAACGTGCTGGCTCTGGTTCATCTGCTTTCTATTACTACAATAATGCTAA GTAAAAAACCTCCAAAAACCTCAGTGGCATCTAACAATAAGCATTTGTTGCTCACACTCATTTCACATTG GTTTTGGTTGTGAATTACATGTTTGCAGCAGGCACCATAGTGGTGTGTGATGTCCCCTTAGCTGTATCCA CATATGGACACAGGAATTTGCTCTTTTTATCTCTTTTTATTTTCTTGGTTACAGACATGTGACTTTTTTT TTTGAAAGGTAACAATCACTTTCTCATATGTTATTTGATGCTAGTGGTCATAGCCTATTAGTCACATTTG TTTCAATGAGAAAGAAAAACCAGTACACGGTTATGCTAAGGATTTCAGTCCCTGGGGTGAGAGCCGTCTC GAATGTCTCCCCACTTCATAACTCCTCCACACATCATAGTTGGATAGTGAGCTCTGCTGATATTGGCAGG ACTTGCTCTGGTCTGGCTGTAGTCTGACGGAGCCTGGCCCTGGGTGTGCTGTGCAGGCTGACTCAGCTCT CCCCACACCTATCTCATGTTCCAGTCAGGCAGTAACTGGTGAAGAAGCCAAGCTAGGAACCAGGATATCT GGCTCCTGAGCTAAAGTCTTAAAACACTATCATATTGCCTTCCAAATATAACACCAAATACTAGGTGCAT ATCACCCACACTGTTTTCAGACCTCTGCCAAAATTGGGATTCTTTGTGGTATGAAGAGACACGGCTTTGG GGCTGGCCCGGCTGTGGCAGTGAGGTGAACACAAAGGGATGTTCTTCAGAGATTACAGTCCAGCCCTGAA GCAACAACTAGGAGACTGTTTCAGCAAGTGAGGACAGGGCTGTGTGGGGTTCTATCCTCTTTATAACTTC CACTAGCACTGAAATCGTGTTCTCTGGTTACATCCAACCAGAACCTTCTTTGTCATTTTTGGGATAGAAA GGGACTAGTTTATCCTCAAATTATTTATGGAGATTTTATATAATATAGTGTTTCTCTCCACATTTTCTGT ATATAACAAAAGTCCTCCTTTTAGTGTGTGTATACACATATATATACACATATATATGTGTGTGTGTATG TGTGTGTGTATATATATATAGACATATATACACGGTTATGCTAAGGATTTCAGTCCCTGGGGTGAGAGCC TTCCCGAATGCTTCCCACCTTCATAACTCCTCCACACATCTCAGTGGGCCACTGAGCACAGCAATGGGCA TGACAGTTATTAAAACACTTTATAAATGCTTCGATCCTTTACCAGTATGAGTTAGTCTCTGGAGCTCCTA ATACTTCATTAGTACTGCATGGACTGAGTTAAAAGTTAATTCAAAATCTCAATTTATCCAAATCTGTTTC GTTCTTTCCAGGCACCACCCACCTATGATACTGTGCTACAGATGGAGTATCTTGACATGGTGGTGAATGA AACGCTCAGATTATTCCCAATTGCTATGAGACTTGAGAGGGTCTGCAAAAAAGATGTTGAGATCAATGGG ATGTTCATTCCCAAAGGGGTGGTGGTGATGATTCCAAGCTATGCTCTTCACCGTGACCCAAAGTACTGGA CAGAGCCTGAGAAGTTCCTCCCTGAAAGGTACAAGGCCCCTGGGAAGGGAGCCCTCCCTGAACCAGCCTG GTTCAAGCATATTCTGCCTCTCTTAATCTACAGGACAGTCATGTGGTTGTATAATTATTTGCTTGTATTT TTATATTTAGAGATTTTTTTAATCATCAAATTGATTATTGTCACACTTTACAAACCATAGACTAGAAAAA AGAAAACTACAGTCATCCACAATTCCAACAACTTACGATGAAGGTCATCAGTTATGTCCTTATGGGTCAT CAGTGTCCAAAATGTAAGGACTCTTTTAAAAACACATGATCACAATGCTATTATTATGTCCCCCAAATGA ATATTTTTTTCATAAATATAATCAAATATTTAGGAATAACATTTTAATAAAAAACATGCATCTAATCTTC AAAGAATTTTATAGCTTACTGGAACAGATAGACAAAGAAAGCAGTGATGATACTGCATTACATCGGTACA GTAGCATCATATGCCTGTGTAAATTATCTGACTTCAACTATTCTATGGAGGTGTGGGGGAGAAAGAGGGA GAGATGGAGAGAAGAAGAAGGAGGAGAAGGAGGGAGAAGACAAGGTAAGGAGGAGAAGGAGGAGAATTAG AAAAACAAGAGAGGAGATGAGAAGGAAAGTGCAAAATAACAATTTTGAAATAGTACAAGACAATTTCCCC TTCTCCTTCCTCATGACCAATGTAAGTGTGACTTGAGGCAGGAACCTACTTTTCCATCAGTCAGTCCCAT CACTTATGTGCCTTTTATAGTGTGGACACATCACCACCCTGAATATAATTTCAGTGTTTAGAAATAAGTA TTCTTTGCAACACTATTTATCTCATCTCAACAAGACTGAAAGCTCCTATAGTGTCAGGAGAGTAGAAAGG ATCTGTAGCTTACAATTCTCATAGCAAAATAAGCATAGCAGGATTTCAATGACCAGCCCACAAAAGTATC CTGTGTACTACTAGTTGAGGGGTGGCCCCTAAGTAAGAAACCCTAACATGTAACTCTTAGGGGTATTATG TCATTAACTTTTTAAAAATCTACCAACGTGGAACCAGATTCAGCAAGAAGAACAAGGACAACATAGATCC TTACATATACACACCCTTTGGAAGTGGACCCAGAAACTGCATTGGCATGAGGTTTGCTCTCATGAACATG AAACTTGCTCTAATCAGAGTCCTTCAGAACTTCTCCTTCAAACCTTGTAAAGAAACACAGGTTAGTCAAT TTTCTATAAAAATAATGTTGTATTAATAATTCTTTTAACTGAGTGGTCTGTATTTTTTAAAAAGAATATG CTTGTTTAATCTTTTACTAATTTGTTCTCTGGGCCAAAGAATCAATTAGGCCCATCTGTGATCTTTAAGG GTGCTTCAGTTCTGGAGTTCAAAAGCTGTAGCATCAAAAACATCATGTAAAGCCCATGTAGATTAGCATG GCATAATTATCTGCAGTCTCCTTGAACTTGAGCAAAGTTTACATTCAGTTTCAAGTCGATTGGAAAGATG GGGAAGTATTTTGCACAGTCATGAAGTGTAATGATTACCTTGTTGTGACTTTTGAATGCTGCTCTTCCCA ACCAGAACTTGGAGAAGCTTTCTCATGAGAGTGGCTCCCAACCACTAGCTGTACATTGGAATCACCAGGG AGCTTTAAAAATTCATGATGTCTGGGATATCACAGAAATTCTAAACTAATTTGCCCAGAGTGTGGCTTTA AAAGCTTCCCCATTGCTTCTCATGTGAAGCCAAGGTTGAGAATGACTAATTTAAGGCATTTCTGGTGGAT ATAAAGGACTACCACAGTCCAAGGCCATCCTGACTGACCTCACCTTCCAGGTGCCTAGCTCCATCCAGCT GGGCTCCTTTTCAACCCAATTATAACTCTATTAATGTTGTTCCCAGCCAGGCATGGTGGCTCATGCCTGT AATCCCAGCACTTTGGGAGGCCGAAGCAGGCGGATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAAC ACGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTACCCTGGAGAGGTGGCAGGCACCTGTAGTCCC AGCTACTCTGGAGGCTGAGGCAGGAGAATGGCATGAACCCCAGGGAGCGGAGCCTGCAGTGAGCCGAGAT TGGGCCACTGCACTCCAGCCTGGGTGACAGCGAGACTCTGTCTCAAAAAAAAAAAAATGTTGTTCCCTTT CTCCTCATTTTGTTCTTATCTTTCAAGTCCTAGTTCAATCCCCAAGCCCCTCCAAAGTGTCTTCTCCTCC TAGTCCAGGGCCCATTTACTTCTCTGCTCTGTTATTGGATACTGGAGGCTATTATCATAAATTTGACAAT TTGCCATTAAATCATTGAGTTTTATTCTCTATATTTTCTTTGTATCTAAAATGTCTTCCCCCCTCCATTA ACAATATCCTCTCATTTTATTCCTTTTTAAAATATCCCAGTGGTGCCTTGCAAGGGACTGTATCTAATGC AAGCATTTGGTAAATGTTTAAGGAGTGATGTGCAGTTGATGGCTTGCATACATATATTAAGCTATTTAAT GTGAACCTTTAAACAAATGCCATTCGTGCATATGCATGTGTGTGTGTGTGTGTGCACATGTGGGCATGCA TGTCTGTCTGCAGTGAAAATATATTCAGGGTTTTTGAAAATTTTTAAATAATAAGGTATTATATTTATAG AAAGATTTGAAATATTTTCTCTGAAGAAGTTAAAGAACAGACGTCATTGATTCATATTAAACAATACCCT ATAAATCTTATTTCTAGGTCTCATGTATTTATTATTCAATTCCACCCCTTAAGTAGGCTTTCTATATAGG AGAGGAAGAAGACAGAAATAGTTTCCATATTATTTCCATATTCCATATTATTTGTGGCTTTAGGCCAGCA GTGTAGCTGTATTATATGTGCCCAGACAGGGGACTCAGCCCTGAATAAAAGTGGTCCTCTGGCACACCTG GGATGGGGAAGGTACTCCTTGGTAAGCTCCCAACCTGGCACTTCTTGATCTCCCTGGCAATTTTCTTGCC CATTACTCCATGGAGATCAGAATATCACTCTGTTGTGTCCCCTCAACACGGAAGGAGTGTCTCAATAAGA ATGGGGCTAAAAGTTGAGTCCAAACACTGTAGGAATTGAGAGGTTCCCCACTTGCACTACCCTTGGAAGC CAAGAGAAGATGTTAAAAAATAAAATGGTAATGCTTCCTGAAGGTGTCTTCCCATCTTTACACTGGATGG GTTCAATTGGGAGGAATTACTGGACTCTGGAAGTTGAAGACTGTCCATATAATTAAAATGTACAATAACT ACCCAGGTTTACCTTGCAAGTTTCAACATACACAAAATTAACTTTATATGACTCTTCAAAAACAGTTTGC CATCATACCTAATAATCTGGTTTAAATTTTAAAAACTCATCCATTTTACTTAAAATTTAAATCAAAAAAG AACACAGGTTTCCATGAATTTGTCTCAGGCCTGGCACAGAATAGTACTCCATAAATATTTTGTTAAATGA TAGATGATGAATGCTCTCACTGTCCAATCTTCACACATCTTATAGACTAAGTATAAAGAATCCAAGATTT ATAGTGCTGAAAGTAGTTTTTATATGTTTACAAAGCATTATTGTCATTACTGCATTTTTTTTGCCCATTA CTCCATAGAGATCAGAATATCACTCTGTTGTGTCCCCTCAACACTGAAGGAGTGTCTCACTCACTTTGAT GCTATACTTTCTACTTTTGTTTATTTAATGCTTCTCAATATGCTTGTTTAACTGTTGCAGATCCCCCTGA AATTAAGCTTAGGAGGACTTCTTCAACCAGAAAAACCCGTTGTTCTAAAGGTTGAGTCAAGGGATGGCAC CGTAAGTGGAGCCTGAATTTTCCTAAGGACTTCTGCTTTGCTCTTCAAGAAATCTGTGCCTGAGAACACC AGAGACCTCAAATTACTTTGTGAATAGAACTCTGAAATGAAGATGGGCTTCATCCAATGGACTGCATAAA TAACCGGGGATTCTGTACATGCATTGAGCTCTCTCATTGTCTGTGTAGAGTGTTATACTTGGGAATATAA AGGAGGTGACCAAATCAGTGTGAGGAGGTAGATTTGGCTCCTCTGCTTCTCACGGGACTATTTCCACCAC CCCCAGTTAGCACCATTAACTCCTCCTGAGCTCTGATAAGAGAATCAACATTTCTCAATAATTTCCTCCA CAAATTATTAATGAAAATAAGAATTATTTTGATGGCTCTAACAATGACATTTATATCACATGTTTTCTCT GGAGTATTCTATAAGTTTTATGTTAAATCAATAAAGACCACTTTACAAAAGTATTATCAGATGCTTTCCT GCACATTAAGGAGAAATCTATAGAACTGAATGAGAACCAACAAGTAAATATTTTTGGTCATTGTAATCAC TGTTGGCGTGGGGCCTTTGTCAGAACTAGAATTTGATTATTAACATAGGTGAAAGTTAATCCACTGTGAC TTTGCCCATTGTTTAGAAAGAATATTCATAGTTTAATTATGCCTTTTTTGATCAGGCACAGTGGCTCACG CCTGTAATCCTAGCAGTTTGGGAGGCTGAGCCGGGTGGATCGCCTGAGGTCAGGAGTTCAAGACAAGCCT GGCCTACATGGTTGAAACCCCATCTCTACTAAAAATACACAAATTAGCTAGGCATGGTGGACTCGCCTGT AATCTCACTACACAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGATGTTGAAGTGAGCTG AGATTGCACCACTGCACTCCAGTCTGGGTGAGAGTGAGACTCAGTCTTAAAAAAATATGCCTTTTTGAAG CACGTACATTTTGTAACAAAGAACTGAAGCTCTTATTATATTATTAGTTTTGATTTAATGTTTTCAGCCC ATCTCCTTTCATATTTCTGGGAGACAGAAAACATGTTTCCCTACACCTCTTGCATTCCATCCTCAACACC CAACTGTCTCGATGCAATGAACACTTAATAAAAAACAGTCGATTGGTCAATTGATTGAGCAATAAGCCT Download Select all
Length	27229
OMIM ID	124010
HGNC ID	HGNC:2637
Unigene ID	Hs.728751
Ensembl ID	ENSG00000160868
PharmGKB ID	PA130

mRNA Information

mRNA ID	NM_001202855.2
Exon	join(1..178,4104..4197,6109..6161,11500..11599, 13954..14067,14333..14421,15687..15835,16934..17058, 17746..17812,20174..20334,21922..22148,23208..23370, 25961..27229)
mRNA Sequence	>1576 AATCACTGCTGTGCAGGGCAGGAAAGCTCCATGCACATAGCCCAGCAAAGAGCAACACAGAGCT GAAAGGAAGACTCAGAGGAGAGAGATAAGTAAGGAAAGTAGTGATGGCTCTCATCCCAGACTTG GCCATGGAAACCTGGCTTCTCCTGGCTGTCAGCCTGGTGCTCCTCTATCTATATGGAACCCATT CACATGGACTTTTTAAGAAGCTTGGAATTCCAGGGCCCACACCTCTGCCTTTTTTGGGAAATAT TTTGTCCTACCATAAGGGCTTTTGTATGTTTGACATGGAATGTCATAAAAAGTATGGAAAAGTG TGGGGCTTTTATGATGGTCAACAGCCTGTGCTGGCTATCACAGATCCTGACATGATCAAAACAG TGCTAGTGAAAGAATGTTATTCTGTCTTCACAAACCGGAGGCCTTTTGGTCCAGTGGGATTTAT GAAAAGTGCCATCTCTATAGCTGAGGATGAAGAATGGAAGAGATTACGATCATTGCTGTCTCCA ACCTTCACCAGTGGAAAACTCAAGGAGATGGTCCCTATCATTGCCCAGTATGGAGATGTGTTGG TGAGAAATCTGAGGCGGGAAGCAGAGACAGGCAAGCCTGTCACCTTGAAAGACGTCTTTGGGGC CTACAGCATGGATGTGATCACTAGCACATCATTTGGAGTGAACATCGACTCTCTCAACAATCCA CAAGACCCCTTTGTGGAAAACACCAAGAAGCTTTTAAGATTTGATTTTTTGGATCCATTCTTTC TCTCAATAATCTTTCCATTCCTCATCCCAATTCTTGAAGTATTAAATATCTGTGTGTTTCCAAG AGAAGTTACAAATTTTTTAAGAAAATCTGTAAAAAGGATGAAAGAAAGTCGCCTCGAAGATACA CAAAAGCACCGAGTGGATTTCCTTCAGCTGATGATTGACTCTCAGAATTCAAAAGAAACTGAGT CCCACAAAGCTCTGTCCGATCTGGAGCTCGTGGCCCAATCAATTATCTTTATTTTTGCTGGCTA TGAAACCACGAGCAGTGTTCTCTCCTTCATTATGTATGAACTGGCCACTCACCCTGATGTCCAG CAGAAACTGCAGGAGGAAATTGATGCAGTTTTACCCAATAAGGCACCACCCACCTATGATACTG TGCTACAGATGGAGTATCTTGACATGGTGGTGAATGAAACGCTCAGATTATTCCCAATTGCTAT GAGACTTGAGAGGGTCTGCAAAAAAGATGTTGAGATCAATGGGATGTTCATTCCCAAAGGGGTG GTGGTGATGATTCCAAGCTATGCTCTTCACCGTGACCCAAAGTACTGGACAGAGCCTGAGAAGT TCCTCCCTGAAAGATTCAGCAAGAAGAACAAGGACAACATAGATCCTTACATATACACACCCTT TGGAAGTGGACCCAGAAACTGCATTGGCATGAGGTTTGCTCTCATGAACATGAAACTTGCTCTA ATCAGAGTCCTTCAGAACTTCTCCTTCAAACCTTGTAAAGAAACACAGATCCCCCTGAAATTAA GCTTAGGAGGACTTCTTCAACCAGAAAAACCCGTTGTTCTAAAGGTTGAGTCAAGGGATGGCAC CGTAAGTGGAGCCTGAATTTTCCTAAGGACTTCTGCTTTGCTCTTCAAGAAATCTGTGCCTGAG AACACCAGAGACCTCAAATTACTTTGTGAATAGAACTCTGAAATGAAGATGGGCTTCATCCAAT GGACTGCATAAATAACCGGGGATTCTGTACATGCATTGAGCTCTCTCATTGTCTGTGTAGAGTG TTATACTTGGGAATATAAAGGAGGTGACCAAATCAGTGTGAGGAGGTAGATTTGGCTCCTCTGC TTCTCACGGGACTATTTCCACCACCCCCAGTTAGCACCATTAACTCCTCCTGAGCTCTGATAAG AGAATCAACATTTCTCAATAATTTCCTCCACAAATTATTAATGAAAATAAGAATTATTTTGATG GCTCTAACAATGACATTTATATCACATGTTTTCTCTGGAGTATTCTATAAGTTTTATGTTAAAT CAATAAAGACCACTTTACAAAAGTATTATCAGATGCTTTCCTGCACATTAAGGAGAAATCTATA GAACTGAATGAGAACCAACAAGTAAATATTTTTGGTCATTGTAATCACTGTTGGCGTGGGGCCT TTGTCAGAACTAGAATTTGATTATTAACATAGGTGAAAGTTAATCCACTGTGACTTTGCCCATT GTTTAGAAAGAATATTCATAGTTTAATTATGCCTTTTTTGATCAGGCACAGTGGCTCACGCCTG TAATCCTAGCAGTTTGGGAGGCTGAGCCGGGTGGATCGCCTGAGGTCAGGAGTTCAAGACAAGC CTGGCCTACATGGTTGAAACCCCATCTCTACTAAAAATACACAAATTAGCTAGGCATGGTGGAC TCGCCTGTAATCTCACTACACAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGGAGGCGGAT GTTGAAGTGAGCTGAGATTGCACCACTGCACTCCAGTCTGGGTGAGAGTGAGACTCAGTCTTAA AAAAATATGCCTTTTTGAAGCACGTACATTTTGTAACAAAGAACTGAAGCTCTTATTATATTAT TAGTTTTGATTTAATGTTTTCAGCCCATCTCCTTTCATATTTCTGGGAGACAGAAAACATGTTT CCCTACACCTCTTGCATTCCATCCTCAACACCCAACTGTCTCGATGCAATGAACACTTAATAAA AAACAGTCGATTGGTCAATTGATTGAGCAATAAGCCT Download Select all
Length	2789

CDS Information

Location	join(108..178,4104..4197,6109..6161,11500..11599, 13954..14067,14333..14421,15687..15835,16934..17058, 17746..17812,20174..20334,21922..22148,23208..23370, 25961..26056)
CDS Sequence	>gi\|322960937:108-1616 Homo sapiens cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4), transcript variant 2, mRNA ATGGCTCTCATCCCAGACTTGGCCATGGAAACCTGGCTTCTCCTGGCTGTCAGCCTGGTGCTCCTCTATC TATATGGAACCCATTCACATGGACTTTTTAAGAAGCTTGGAATTCCAGGGCCCACACCTCTGCCTTTTTT GGGAAATATTTTGTCCTACCATAAGGGCTTTTGTATGTTTGACATGGAATGTCATAAAAAGTATGGAAAA GTGTGGGGCTTTTATGATGGTCAACAGCCTGTGCTGGCTATCACAGATCCTGACATGATCAAAACAGTGC TAGTGAAAGAATGTTATTCTGTCTTCACAAACCGGAGGCCTTTTGGTCCAGTGGGATTTATGAAAAGTGC CATCTCTATAGCTGAGGATGAAGAATGGAAGAGATTACGATCATTGCTGTCTCCAACCTTCACCAGTGGA AAACTCAAGGAGATGGTCCCTATCATTGCCCAGTATGGAGATGTGTTGGTGAGAAATCTGAGGCGGGAAG CAGAGACAGGCAAGCCTGTCACCTTGAAAGACGTCTTTGGGGCCTACAGCATGGATGTGATCACTAGCAC ATCATTTGGAGTGAACATCGACTCTCTCAACAATCCACAAGACCCCTTTGTGGAAAACACCAAGAAGCTT TTAAGATTTGATTTTTTGGATCCATTCTTTCTCTCAATAATCTTTCCATTCCTCATCCCAATTCTTGAAG TATTAAATATCTGTGTGTTTCCAAGAGAAGTTACAAATTTTTTAAGAAAATCTGTAAAAAGGATGAAAGA AAGTCGCCTCGAAGATACACAAAAGCACCGAGTGGATTTCCTTCAGCTGATGATTGACTCTCAGAATTCA AAAGAAACTGAGTCCCACAAAGCTCTGTCCGATCTGGAGCTCGTGGCCCAATCAATTATCTTTATTTTTG CTGGCTATGAAACCACGAGCAGTGTTCTCTCCTTCATTATGTATGAACTGGCCACTCACCCTGATGTCCA GCAGAAACTGCAGGAGGAAATTGATGCAGTTTTACCCAATAAGGCACCACCCACCTATGATACTGTGCTA CAGATGGAGTATCTTGACATGGTGGTGAATGAAACGCTCAGATTATTCCCAATTGCTATGAGACTTGAGA GGGTCTGCAAAAAAGATGTTGAGATCAATGGGATGTTCATTCCCAAAGGGGTGGTGGTGATGATTCCAAG CTATGCTCTTCACCGTGACCCAAAGTACTGGACAGAGCCTGAGAAGTTCCTCCCTGAAAGATTCAGCAAG AAGAACAAGGACAACATAGATCCTTACATATACACACCCTTTGGAAGTGGACCCAGAAACTGCATTGGCA TGAGGTTTGCTCTCATGAACATGAAACTTGCTCTAATCAGAGTCCTTCAGAACTTCTCCTTCAAACCTTG TAAAGAAACACAGATCCCCCTGAAATTAAGCTTAGGAGGACTTCTTCAACCAGAAAAACCCGTTGTTCTA AAGGTTGAGTCAAGGGATGGCACCGTAAGTGGAGCCTGA Download Select all
CCDS ID	-

Protein Information

Protein ID	NP_001189784.1
Protein Name	Cytochrome P450, family 3, subfamily A, polypeptide 4
Molecular Wt. (Da)	57125
Protein Sequence	>1576 MALIPDLAMETWLLLAVSLVLLYLYGTHSHGLFKKLGIPGPTPLPFLGNILSYHKGFCMFDMEC HKKYGKVWGFYDGQQPVLAITDPDMIKTVLVKECYSVFTNRRPFGPVGFMKSAISIAEDEEWKR LRSLLSPTFTSGKLKEMVPIIAQYGDVLVRNLRREAETGKPVTLKDVFGAYSMDVITSTSFGVN IDSLNNPQDPFVENTKKLLRFDFLDPFFLSIIFPFLIPILEVLNICVFPREVTNFLRKSVKRMK ESRLEDTQKHRVDFLQLMIDSQNSKETESHKALSDLELVAQSIIFIFAGYETTSSVLSFIMYEL ATHPDVQQKLQEEIDAVLPNKAPPTYDTVLQMEYLDMVVNETLRLFPIAMRLERVCKKDVEING MFIPKGVVVMIPSYALHRDPKYWTEPEKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFAL MNMKLALIRVLQNFSFKPCKETQIPLKLSLGGLLQPEKPVVLKVESRDGTVSGA Download Select all
Length	502
Uniprot ID	O43182
Ensembl Protein ID	ENSP00000302312

Post-translational Modification Information (Source : HPRD)

No matching records could be found.

Enzyme Information

EC	1.14.13.67
Name	quinine 3-monooxygenase quinine 3-hydroxylase
Class	Oxidoreductases; Acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2; With NADH or NADPH as one donor, and incorporation of one atom of oxygen into the other donor
Sysname	quinine,NADPH:oxygen oxidoreductase
Substrate	quinine [CPD:C06526]; NADPH [CPD:C00005]; H+ [CPD:C00080]; O2
Product	3-hydroxyquinine [CPD:C07344]; NADP+ [CPD:C00006]; H2O
Reaction (IUBMB)

PPi Information

(Click to view network : Source STRING) View

Interactant Gene ID (Source: HPRD)	Gene Symbol	HPRD ID	Ref Seq ID	Technique	References
7364	UGT2B7	2508	NP_001065.2	in vitro;in vivo	15611481

Pathway Information

Pathway Name	Pathway ID
Bile secretion	hsa04976
Chemical carcinogenesis	hsa05204
Drug metabolism - cytochrome P450	hsa00982
Drug metabolism - other enzymes	hsa00983
Linoleic acid metabolism	hsa00591
Metabolic pathways	hsa01100
Metabolism of xenobiotics by cytochrome P450	hsa00980
Retinol metabolism	hsa00830
Steroid hormone biosynthesis	hsa00140

Structure Information

PDB ID	1TQN
Resolution	2.05
Method	X-RAY DIFFRACTION�
Chains	A
Molecule	cytochrome P450 3A4
Model	View

Domain Information

ID	Location	Description
pfam00067	39-493	p450
cl12078	39-493	p450 superfamily
COG2124	32-465	CypX
PLN02290	32-465	PLN02290
PTZ00404	33-496	PTZ00404
PLN02936	66-465	PLN02936
PLN03112	39-467	PLN03112
PLN02183	39-466	PLN02183
PLN02394	39-467	PLN02394
PLN02655	38-466	PLN02655
PLN02687	39-496	PLN02687
PLN03195	121-465	PLN03195
PLN02302	39-474	PLN02302
PLN02426	172-466	PLN02426
PLN00168	39-466	PLN00168
PLN00110	39-496	PLN00110
PLN02966	39-466	PLN02966
PLN02987	243-473	PLN02987
PLN02196	39-456	PLN02196
PLN03234	39-491	PLN03234
TIGR04538	249-467	P450_cycloAA_1
PLN02774	250-444	PLN02774
PLN02971	39-496	PLN02971
PLN03018	294-496	PLN03018
PLN02500	287-466	PLN02500
PLN02169	252-466	PLN02169
PLN03141	251-448	PLN03141
PLN02648	301-432	PLN02648
TIGR04458	283-463	CYP450_TxtE
PLN02738	68-466	PLN02738
TIGR04515	359-418	P450_rel_GT_act

Ontology Information

HPRD ID	2124
Molecular Class	Enzyme: Oxidase
Molecular Function	GTPase activator activity (GO:0005096)
Biological Process	Cell communication (GO:0007154); Signal transduction (GO:0007165)

SNP Information

View SNP Geneview Report

Drug Information

Uniprot ID DrugBank ID Name Type
P08684 DB00041 Aldesleukin BiotechDrug
P08684 DB00082 Pegvisomant BiotechDrug
P08684 DB00091 Cyclosporine SmallMoleculeDrug
P08684 DB00136 Calcitriol SmallMoleculeDrug
P08684 DB00153 Ergocalciferol SmallMoleculeDrug
P08684 DB00169 Cholecalciferol SmallMoleculeDrug
P08684 DB00175 Pravastatin SmallMoleculeDrug
P08684 DB00176 Fluvoxamine SmallMoleculeDrug
P08684 DB00180 Flunisolide SmallMoleculeDrug
P08684 DB00184 Nicotine SmallMoleculeDrug
P08684 DB00185 Cevimeline SmallMoleculeDrug
P08684 DB00188 Bortezomib SmallMoleculeDrug
P08684 DB00193 Tramadol SmallMoleculeDrug
P08684 DB00196 Fluconazole SmallMoleculeDrug
P08684 DB00199 Erythromycin SmallMoleculeDrug
P08684 DB00201 Caffeine SmallMoleculeDrug
P08684 DB00203 Sildenafil SmallMoleculeDrug
P08684 DB00204 Dofetilide SmallMoleculeDrug
P08684 DB00207 Azithromycin SmallMoleculeDrug
P08684 DB00208 Ticlopidine SmallMoleculeDrug
P08684 DB00213 Pantoprazole SmallMoleculeDrug
P08684 DB00215 Citalopram SmallMoleculeDrug
P08684 DB00216 Eletriptan SmallMoleculeDrug
P08684 DB00220 Nelfinavir SmallMoleculeDrug
P08684 DB00224 Indinavir SmallMoleculeDrug
P08684 DB00227 Lovastatin SmallMoleculeDrug
P08684 DB00231 Temazepam SmallMoleculeDrug
P08684 DB00234 Reboxetine SmallMoleculeDrug
P08684 DB00238 Nevirapine SmallMoleculeDrug
P08684 DB00239 Oxiconazole SmallMoleculeDrug
P08684 DB00240 Alclometasone SmallMoleculeDrug
P08684 DB00243 Ranolazine SmallMoleculeDrug
P08684 DB00246 Ziprasidone SmallMoleculeDrug
P08684 DB00248 Cabergoline SmallMoleculeDrug
P08684 DB00250 Dapsone SmallMoleculeDrug
P08684 DB00252 Phenytoin SmallMoleculeDrug
P08684 DB00254 Doxycycline SmallMoleculeDrug
P08684 DB00255 Diethylstilbestrol SmallMoleculeDrug
P08684 DB00257 Clotrimazole SmallMoleculeDrug
P08684 DB00259 Sulfanilamide SmallMoleculeDrug
P08684 DB00268 Ropinirole SmallMoleculeDrug
P08684 DB00270 Isradipine SmallMoleculeDrug
P08684 DB00273 Topiramate SmallMoleculeDrug
P08684 DB00277 Theophylline SmallMoleculeDrug
P08684 DB00278 Argatroban SmallMoleculeDrug
P08684 DB00280 Disopyramide SmallMoleculeDrug
P08684 DB00281 Lidocaine SmallMoleculeDrug
P08684 DB00283 Clemastine SmallMoleculeDrug
P08684 DB00285 Venlafaxine SmallMoleculeDrug
P08684 DB00286 Conjugated Estrogens SmallMoleculeDrug
P08684 DB00289 Atomoxetine SmallMoleculeDrug
P08684 DB00294 Etonogestrel SmallMoleculeDrug
P08684 DB00295 Morphine SmallMoleculeDrug
P08684 DB00296 Ropivacaine SmallMoleculeDrug
P08684 DB00297 Bupivacaine SmallMoleculeDrug
P08684 DB00301 Flucloxacillin SmallMoleculeDrug
P08684 DB00307 Bexarotene SmallMoleculeDrug
P08684 DB00309 Vindesine SmallMoleculeDrug
P08684 DB00312 Pentobarbital SmallMoleculeDrug
P08684 DB00313 Valproic Acid SmallMoleculeDrug
P08684 DB00316 Acetaminophen SmallMoleculeDrug
P08684 DB00317 Gefitinib SmallMoleculeDrug
P08684 DB00318 Codeine SmallMoleculeDrug
P08684 DB00320 Dihydroergotamine SmallMoleculeDrug
P08684 DB00321 Amitriptyline SmallMoleculeDrug
P08684 DB00324 Fluorometholone SmallMoleculeDrug
P08684 DB00327 Hydromorphone SmallMoleculeDrug
P08684 DB00332 Ipratropium bromide SmallMoleculeDrug
P08684 DB00333 Methadone SmallMoleculeDrug
P08684 DB00334 Olanzapine SmallMoleculeDrug
P08684 DB00337 Pimecrolimus SmallMoleculeDrug
P08684 DB00338 Omeprazole SmallMoleculeDrug
P08684 DB00339 Pyrazinamide SmallMoleculeDrug
P08684 DB00343 Diltiazem SmallMoleculeDrug
P08684 DB00346 Alfuzosin SmallMoleculeDrug
P08684 DB00347 Trimethadione SmallMoleculeDrug
P08684 DB00349 Clobazam SmallMoleculeDrug
P08684 DB00353 Methylergometrine SmallMoleculeDrug
P08684 DB00356 Chlorzoxazone SmallMoleculeDrug
P08684 DB00357 Aminoglutethimide SmallMoleculeDrug
P08684 DB00358 Mefloquine SmallMoleculeDrug
P08684 DB00359 Sulfadiazine SmallMoleculeDrug
P08684 DB00361 Vinorelbine SmallMoleculeDrug
P08684 DB00363 Clozapine SmallMoleculeDrug
P08684 DB00367 Levonorgestrel SmallMoleculeDrug
P08684 DB00370 Mirtazapine SmallMoleculeDrug
P08684 DB00377 Palonosetron SmallMoleculeDrug
P08684 DB00379 Mexiletine SmallMoleculeDrug
P08684 DB00381 Amlodipine SmallMoleculeDrug
P08684 DB00390 Digoxin SmallMoleculeDrug
P08684 DB00393 Nimodipine SmallMoleculeDrug
P08684 DB00396 Progesterone SmallMoleculeDrug
P08684 DB00398 Sorafenib SmallMoleculeDrug
P08684 DB00400 Griseofulvin SmallMoleculeDrug
P08684 DB00401 Nisoldipine SmallMoleculeDrug
P08684 DB00402 Eszopiclone SmallMoleculeDrug
P08684 DB00404 Alprazolam SmallMoleculeDrug
P08684 DB00420 Promazine SmallMoleculeDrug
P08684 DB00425 Zolpidem SmallMoleculeDrug
P08684 DB00426 Famciclovir SmallMoleculeDrug
P08684 DB00433 Prochlorperazine SmallMoleculeDrug
P08684 DB00435 Nitric Oxide SmallMoleculeDrug
P08684 DB00440 Trimethoprim SmallMoleculeDrug
P08684 DB00443 Betamethasone SmallMoleculeDrug
P08684 DB00444 Teniposide SmallMoleculeDrug
P08684 DB00446 Chloramphenicol SmallMoleculeDrug
P08684 DB00448 Lansoprazole SmallMoleculeDrug
P08684 DB00451 Levothyroxine SmallMoleculeDrug
P08684 DB00454 Pethidine SmallMoleculeDrug
P08684 DB00455 Loratadine SmallMoleculeDrug
P08684 DB00458 Imipramine SmallMoleculeDrug
P08684 DB00468 Quinine SmallMoleculeDrug
P08684 DB00470 Dronabinol SmallMoleculeDrug
P08684 DB00471 Montelukast SmallMoleculeDrug
P08684 DB00472 Fluoxetine SmallMoleculeDrug
P08684 DB00475 Chlordiazepoxide SmallMoleculeDrug
P08684 DB00477 Chlorpromazine SmallMoleculeDrug
P08684 DB00481 Raloxifene SmallMoleculeDrug
P08684 DB00482 Celecoxib SmallMoleculeDrug
P08684 DB00485 Dicloxacillin SmallMoleculeDrug
P08684 DB00490 Buspirone SmallMoleculeDrug
P08684 DB00495 Zidovudine SmallMoleculeDrug
P08684 DB00496 Darifenacin SmallMoleculeDrug
P08684 DB00497 Oxycodone SmallMoleculeDrug
P08684 DB00499 Flutamide SmallMoleculeDrug
P08684 DB00501 Cimetidine SmallMoleculeDrug
P08684 DB00502 Haloperidol SmallMoleculeDrug
P08684 DB00503 Ritonavir SmallMoleculeDrug
P08684 DB00514 Dextromethorphan SmallMoleculeDrug
P08684 DB00518 Albendazole SmallMoleculeDrug
P08684 DB00520 Caspofungin SmallMoleculeDrug
P08684 DB00528 Lercanidipine SmallMoleculeDrug
P08684 DB00530 Erlotinib SmallMoleculeDrug
P08684 DB00531 Cyclophosphamide SmallMoleculeDrug
P08684 DB00537 Ciprofloxacin SmallMoleculeDrug
P08684 DB00539 Toremifene SmallMoleculeDrug
P08684 DB00540 Nortriptyline SmallMoleculeDrug
P08684 DB00541 Vincristine SmallMoleculeDrug
P08684 DB00545 Pyridostigmine SmallMoleculeDrug
P08684 DB00546 Adinazolam SmallMoleculeDrug
P08684 DB00549 Zafirlukast SmallMoleculeDrug
P08684 DB00553 Methoxsalen SmallMoleculeDrug
P08684 DB00559 Bosentan SmallMoleculeDrug
P08684 DB00564 Carbamazepine SmallMoleculeDrug
P08684 DB00567 Cephalexin SmallMoleculeDrug
P08684 DB00570 Vinblastine SmallMoleculeDrug
P08684 DB00571 Propranolol SmallMoleculeDrug
P08684 DB00575 Clonidine SmallMoleculeDrug
P08684 DB00582 Voriconazole SmallMoleculeDrug
P08684 DB00584 Enalapril SmallMoleculeDrug
P08684 DB00586 Diclofenac SmallMoleculeDrug
P08684 DB00588 Fluticasone Propionate SmallMoleculeDrug
P08684 DB00589 Lisuride SmallMoleculeDrug
P08684 DB00593 Ethosuximide SmallMoleculeDrug
P08684 DB00599 Thiopental SmallMoleculeDrug
P08684 DB00602 Ivermectin SmallMoleculeDrug
P08684 DB00603 Medroxyprogesterone Acetate SmallMoleculeDrug
P08684 DB00604 Cisapride SmallMoleculeDrug
P08684 DB00607 Nafcillin SmallMoleculeDrug
P08684 DB00608 Chloroquine SmallMoleculeDrug
P08684 DB00612 Bisoprolol SmallMoleculeDrug
P08684 DB00615 Rifabutin SmallMoleculeDrug
P08684 DB00617 Paramethadione SmallMoleculeDrug
P08684 DB00619 Imatinib SmallMoleculeDrug
P08684 DB00620 Triamcinolone SmallMoleculeDrug
P08684 DB00622 Nicardipine SmallMoleculeDrug
P08684 DB00624 Testosterone SmallMoleculeDrug
P08684 DB00625 Efavirenz SmallMoleculeDrug
P08684 DB00628 Clorazepate SmallMoleculeDrug
P08684 DB00635 Prednisone SmallMoleculeDrug
P08684 DB00636 Clofibrate SmallMoleculeDrug
P08684 DB00637 Astemizole SmallMoleculeDrug
P08684 DB00641 Simvastatin SmallMoleculeDrug
P08684 DB00643 Mebendazole SmallMoleculeDrug
P08684 DB00647 Dextropropoxyphene SmallMoleculeDrug
P08684 DB00655 Estrone SmallMoleculeDrug
P08684 DB00656 Trazodone SmallMoleculeDrug
P08684 DB00661 Verapamil SmallMoleculeDrug
P08684 DB00667 Histamine Phosphate SmallMoleculeDrug
P08684 DB00668 Epinephrine SmallMoleculeDrug
P08684 DB00673 Aprepitant SmallMoleculeDrug
P08684 DB00674 Galantamine SmallMoleculeDrug
P08684 DB00675 Tamoxifen SmallMoleculeDrug
P08684 DB00678 Losartan SmallMoleculeDrug
P08684 DB00682 Warfarin SmallMoleculeDrug
P08684 DB00683 Midazolam SmallMoleculeDrug
P08684 DB00688 Mycophenolate mofetil SmallMoleculeDrug
P08684 DB00690 Flurazepam SmallMoleculeDrug
P08684 DB00694 Daunorubicin SmallMoleculeDrug
P08684 DB00696 Ergotamine SmallMoleculeDrug
P08684 DB00700 Eplerenone SmallMoleculeDrug
P08684 DB00701 Amprenavir SmallMoleculeDrug
P08684 DB00703 Methazolamide SmallMoleculeDrug
P08684 DB00705 Delavirdine SmallMoleculeDrug
P08684 DB00706 Tamsulosin SmallMoleculeDrug
P08684 DB00708 Sufentanil SmallMoleculeDrug
P08684 DB00717 Norethindrone SmallMoleculeDrug
P08684 DB00719 Azatadine SmallMoleculeDrug
P08684 DB00724 Imiquimod SmallMoleculeDrug
P08684 DB00726 Trimipramine SmallMoleculeDrug
P08684 DB00731 Nateglinide SmallMoleculeDrug
P08684 DB00734 Risperidone SmallMoleculeDrug
P08684 DB00736 Esomeprazole SmallMoleculeDrug
P08684 DB00738 Pentamidine SmallMoleculeDrug
P08684 DB00741 Hydrocortisone SmallMoleculeDrug
P08684 DB00744 Zileuton SmallMoleculeDrug
P08684 DB00745 Modafinil SmallMoleculeDrug
P08684 DB00748 Carbinoxamine SmallMoleculeDrug
P08684 DB00751 Epinastine SmallMoleculeDrug
P08684 DB00752 Tranylcypromine SmallMoleculeDrug
P08684 DB00755 Tretinoin SmallMoleculeDrug
P08684 DB00757 Dolasetron SmallMoleculeDrug
P08684 DB00758 Clopidogrel SmallMoleculeDrug
P08684 DB00759 Tetracycline SmallMoleculeDrug
P08684 DB00762 Irinotecan SmallMoleculeDrug
P08684 DB00763 Methimazole SmallMoleculeDrug
P08684 DB00768 Olopatadine SmallMoleculeDrug
P08684 DB00769 Hydrocortamate SmallMoleculeDrug
P08684 DB00773 Etoposide SmallMoleculeDrug
P08684 DB00776 Oxcarbazepine SmallMoleculeDrug
P08684 DB00778 Roxithromycin SmallMoleculeDrug
P08684 DB00780 Phenelzine SmallMoleculeDrug
P08684 DB00783 Estradiol SmallMoleculeDrug
P08684 DB00794 Primidone SmallMoleculeDrug
P08684 DB00802 Alfentanil SmallMoleculeDrug
P08684 DB00808 Indapamide SmallMoleculeDrug
P08684 DB00812 Phenylbutazone SmallMoleculeDrug
P08684 DB00813 Fentanyl SmallMoleculeDrug
P08684 DB00814 Meloxicam SmallMoleculeDrug
P08684 DB00818 Propofol SmallMoleculeDrug
P08684 DB00819 Acetazolamide SmallMoleculeDrug
P08684 DB00820 Tadalafil SmallMoleculeDrug
P08684 DB00822 Disulfiram SmallMoleculeDrug
P08684 DB00829 Diazepam SmallMoleculeDrug
P08684 DB00834 Mifepristone SmallMoleculeDrug
P08684 DB00835 Brompheniramine SmallMoleculeDrug
P08684 DB00836 Loperamide SmallMoleculeDrug
P08684 DB00842 Oxazepam SmallMoleculeDrug
P08684 DB00843 Donepezil SmallMoleculeDrug
P08684 DB00845 Clofazimine SmallMoleculeDrug
P08684 DB00850 Perphenazine SmallMoleculeDrug
P08684 DB00853 Temozolomide SmallMoleculeDrug
P08684 DB00856 Chlorphenesin SmallMoleculeDrug
P08684 DB00857 Terbinafine SmallMoleculeDrug
P08684 DB00860 Prednisolone SmallMoleculeDrug
P08684 DB00862 Vardenafil SmallMoleculeDrug
P08684 DB00863 Ranitidine SmallMoleculeDrug
P08684 DB00864 Tacrolimus SmallMoleculeDrug
P08684 DB00865 Benzphetamine SmallMoleculeDrug
P08684 DB00869 Dorzolamide SmallMoleculeDrug
P08684 DB00872 Conivaptan SmallMoleculeDrug
P08684 DB00877 Sirolimus SmallMoleculeDrug
P08684 DB00882 Clomifene SmallMoleculeDrug
P08684 DB00883 Isosorbide Dinitrate SmallMoleculeDrug
P08684 DB00889 Granisetron SmallMoleculeDrug
P08684 DB00897 Triazolam SmallMoleculeDrug
P08684 DB00898 Ethanol SmallMoleculeDrug
P08684 DB00904 Ondansetron SmallMoleculeDrug
P08684 DB00906 Tiagabine SmallMoleculeDrug
P08684 DB00907 Cocaine SmallMoleculeDrug
P08684 DB00908 Quinidine SmallMoleculeDrug
P08684 DB00909 Zonisamide SmallMoleculeDrug
P08684 DB00910 Paricalcitol SmallMoleculeDrug
P08684 DB00911 Tinidazole SmallMoleculeDrug
P08684 DB00912 Repaglinide SmallMoleculeDrug
P08684 DB00916 Metronidazole SmallMoleculeDrug
P08684 DB00918 Almotriptan SmallMoleculeDrug
P08684 DB00921 Buprenorphine SmallMoleculeDrug
P08684 DB00924 Cyclobenzaprine SmallMoleculeDrug
P08684 DB00925 Phenoxybenzamine SmallMoleculeDrug
P08684 DB00932 Tipranavir SmallMoleculeDrug
P08684 DB00938 Salmeterol SmallMoleculeDrug
P08684 DB00943 Zalcitabine SmallMoleculeDrug
P08684 DB00946 Phenprocoumon SmallMoleculeDrug
P08684 DB00947 Fulvestrant SmallMoleculeDrug
P08684 DB00949 Felbamate SmallMoleculeDrug
P08684 DB00951 Isoniazid SmallMoleculeDrug
P08684 DB00956 Hydrocodone SmallMoleculeDrug
P08684 DB00959 Methylprednisolone SmallMoleculeDrug
P08684 DB00962 Zaleplon SmallMoleculeDrug
P08684 DB00969 Alosetron SmallMoleculeDrug
P08684 DB00972 Azelastine SmallMoleculeDrug
P08684 DB00973 Ezetimibe SmallMoleculeDrug
P08684 DB00976 Telithromycin SmallMoleculeDrug
P08684 DB00977 Ethinyl Estradiol SmallMoleculeDrug
P08684 DB00980 Ramelteon SmallMoleculeDrug
P08684 DB00987 Cytarabine SmallMoleculeDrug
P08684 DB00989 Rivastigmine SmallMoleculeDrug
P08684 DB00990 Exemestane SmallMoleculeDrug
P08684 DB00997 Doxorubicin SmallMoleculeDrug
P08684 DB01001 Salbutamol SmallMoleculeDrug
P08684 DB01002 Levobupivacaine SmallMoleculeDrug
P08684 DB01006 Letrozole SmallMoleculeDrug
P08684 DB01007 Tioconazole SmallMoleculeDrug
P08684 DB01008 Busulfan SmallMoleculeDrug
P08684 DB01011 Metyrapone SmallMoleculeDrug
P08684 DB01012 Cinacalcet SmallMoleculeDrug
P08684 DB01015 Sulfamethoxazole SmallMoleculeDrug
P08684 DB01016 Glyburide SmallMoleculeDrug
P08684 DB01018 Guanfacine SmallMoleculeDrug
P08684 DB01020 Isosorbide Mononitrate SmallMoleculeDrug
P08684 DB01023 Felodipine SmallMoleculeDrug
P08684 DB01026 Ketoconazole SmallMoleculeDrug
P08684 DB01028 Methoxyflurane SmallMoleculeDrug
P08684 DB01029 Irbesartan SmallMoleculeDrug
P08684 DB01030 Topotecan SmallMoleculeDrug
P08684 DB01032 Probenecid SmallMoleculeDrug
P08684 DB01036 Tolterodine SmallMoleculeDrug
P08684 DB01037 Selegiline SmallMoleculeDrug
P08684 DB01039 Fenofibrate SmallMoleculeDrug
P08684 DB01045 Rifampicin SmallMoleculeDrug
P08684 DB01049 Ergoloid mesylate SmallMoleculeDrug
P08684 DB01054 Nitrendipine SmallMoleculeDrug
P08684 DB01058 Praziquantel SmallMoleculeDrug
P08684 DB01059 Norfloxacin SmallMoleculeDrug
P08684 DB01062 Oxybutynin SmallMoleculeDrug
P08684 DB01067 Glipizide SmallMoleculeDrug
P08684 DB01068 Clonazepam SmallMoleculeDrug
P08684 DB01071 Mequitazine SmallMoleculeDrug
P08684 DB01072 Atazanavir SmallMoleculeDrug
P08684 DB01074 Perhexiline SmallMoleculeDrug
P08684 DB01076 Atorvastatin SmallMoleculeDrug
P08684 DB01083 Orlistat SmallMoleculeDrug
P08684 DB01085 Pilocarpine SmallMoleculeDrug
P08684 DB01087 Primaquine SmallMoleculeDrug
P08684 DB01093 Dimethyl sulfoxide SmallMoleculeDrug
P08684 DB01095 Fluvastatin SmallMoleculeDrug
P08684 DB01098 Rosuvastatin SmallMoleculeDrug
P08684 DB01100 Pimozide SmallMoleculeDrug
P08684 DB01103 Quinacrine SmallMoleculeDrug
P08684 DB01104 Sertraline SmallMoleculeDrug
P08684 DB01105 Sibutramine SmallMoleculeDrug
P08684 DB01110 Miconazole SmallMoleculeDrug
P08684 DB01114 Chlorphenamine SmallMoleculeDrug
P08684 DB01115 Nifedipine SmallMoleculeDrug
P08684 DB01118 Amiodarone SmallMoleculeDrug
P08684 DB01126 Dutasteride SmallMoleculeDrug
P08684 DB01127 Econazole SmallMoleculeDrug
P08684 DB01128 Bicalutamide SmallMoleculeDrug
P08684 DB01129 Rabeprazole SmallMoleculeDrug
P08684 DB01131 Proguanil SmallMoleculeDrug
P08684 DB01132 Pioglitazone SmallMoleculeDrug
P08684 DB01136 Carvedilol SmallMoleculeDrug
P08684 DB01137 Levofloxacin SmallMoleculeDrug
P08684 DB01138 Sulfinpyrazone SmallMoleculeDrug
P08684 DB01142 Doxepin SmallMoleculeDrug
P08684 DB01149 Nefazodone SmallMoleculeDrug
P08684 DB01151 Desipramine SmallMoleculeDrug
P08684 DB01156 Bupropion SmallMoleculeDrug
P08684 DB01159 Halothane SmallMoleculeDrug
P08684 DB01166 Cilostazol SmallMoleculeDrug
P08684 DB01167 Itraconazole SmallMoleculeDrug
P08684 DB01169 Arsenic trioxide SmallMoleculeDrug
P08684 DB01170 Guanethidine SmallMoleculeDrug
P08684 DB01173 Orphenadrine SmallMoleculeDrug
P08684 DB01174 Phenobarbital SmallMoleculeDrug
P08684 DB01175 Escitalopram SmallMoleculeDrug
P08684 DB01179 Podofilox SmallMoleculeDrug
P08684 DB01181 Ifosfamide SmallMoleculeDrug
P08684 DB01182 Propafenone SmallMoleculeDrug
P08684 DB01183 Naloxone SmallMoleculeDrug
P08684 DB01184 Domperidone SmallMoleculeDrug
P08684 DB01186 Pergolide SmallMoleculeDrug
P08684 DB01190 Clindamycin SmallMoleculeDrug
P08684 DB01192 Oxymorphone SmallMoleculeDrug
P08684 DB01194 Brinzolamide SmallMoleculeDrug
P08684 DB01196 Estramustine SmallMoleculeDrug
P08684 DB01198 Zopiclone SmallMoleculeDrug
P08684 DB01200 Bromocriptine SmallMoleculeDrug
P08684 DB01201 Rifapentine SmallMoleculeDrug
P08684 DB01204 Mitoxantrone SmallMoleculeDrug
P08684 DB01206 Lomustine SmallMoleculeDrug
P08684 DB01211 Clarithromycin SmallMoleculeDrug
P08684 DB01215 Estazolam SmallMoleculeDrug
P08684 DB01216 Finasteride SmallMoleculeDrug
P08684 DB01217 Anastrozole SmallMoleculeDrug
P08684 DB01218 Halofantrine SmallMoleculeDrug
P08684 DB01219 Dantrolene SmallMoleculeDrug
P08684 DB01220 Rifaximin SmallMoleculeDrug
P08684 DB01221 Ketamine SmallMoleculeDrug
P08684 DB01222 Budesonide SmallMoleculeDrug
P08684 DB01223 Aminophylline SmallMoleculeDrug
P08684 DB01224 Quetiapine SmallMoleculeDrug
P08684 DB01227 Levomethadyl Acetate SmallMoleculeDrug
P08684 DB01229 Paclitaxel SmallMoleculeDrug
P08684 DB01232 Saquinavir SmallMoleculeDrug
P08684 DB01234 Dexamethasone SmallMoleculeDrug
P08684 DB01236 Sevoflurane SmallMoleculeDrug
P08684 DB01238 Aripiprazole SmallMoleculeDrug
P08684 DB01241 Gemfibrozil SmallMoleculeDrug
P08684 DB01242 Clomipramine SmallMoleculeDrug
P08684 DB01246 Alimemazine SmallMoleculeDrug
P08684 DB01248 Docetaxel SmallMoleculeDrug
P08684 DB01253 Ergonovine SmallMoleculeDrug
P08684 DB01254 Dasatinib SmallMoleculeDrug
P08684 DB01256 Retapamulin SmallMoleculeDrug
P08684 DB01259 Lapatinib SmallMoleculeDrug
P08684 DB01261 Sitagliptin SmallMoleculeDrug
P08684 DB01263 Posaconazole SmallMoleculeDrug
P08684 DB01264 Darunavir SmallMoleculeDrug
P08684 DB01268 Sunitinib SmallMoleculeDrug
P08684 DB01275 Hydralazine SmallMoleculeDrug
P08684 DB01301 Rolitetracycline SmallMoleculeDrug
P08684 DB01319 Fosamprenavir SmallMoleculeDrug
P08684 DB01320 Fosphenytoin SmallMoleculeDrug
P08684 DB01321 Josamycin SmallMoleculeDrug
P08684 DB01333 Cefradine SmallMoleculeDrug
P08684 DB01349 Tasosartan SmallMoleculeDrug
P08684 DB01355 Hexobarbital SmallMoleculeDrug
P08684 DB01361 Troleandomycin SmallMoleculeDrug
P08684 DB01369 Quinupristin SmallMoleculeDrug
P08684 DB01380 Cortisone acetate SmallMoleculeDrug
P08684 DB01384 Paramethasone SmallMoleculeDrug
P08684 DB01392 Yohimbine SmallMoleculeDrug
P08684 DB01393 Bezafibrate SmallMoleculeDrug
P08684 DB01394 Colchicine SmallMoleculeDrug
P08684 DB01396 Digitoxin SmallMoleculeDrug
P08684 DB01406 Danazol SmallMoleculeDrug
P08684 DB01409 Tiotropium SmallMoleculeDrug
P08684 DB01410 Ciclesonide SmallMoleculeDrug
P08684 DB01411 Pranlukast SmallMoleculeDrug
P08684 DB01418 Acenocoumarol SmallMoleculeDrug
P08684 DB01424 Aminophenazone SmallMoleculeDrug
P08684 DB01431 Allylestrenol SmallMoleculeDrug
P08684 DB01435 Antipyrine SmallMoleculeDrug
P08684 DB01466 Ethylmorphine SmallMoleculeDrug
P08684 DB01544 Flunitrazepam SmallMoleculeDrug
P08684 DB01551 Dihydrocodeine SmallMoleculeDrug
P08684 DB01558 Bromazepam SmallMoleculeDrug
P08684 DB01559 Clotiazepam SmallMoleculeDrug
P08684 DB01587 Ketazolam SmallMoleculeDrug
P08684 DB01588 Prazepam SmallMoleculeDrug
P08684 DB01589 Quazepam SmallMoleculeDrug
P08684 DB01590 Everolimus SmallMoleculeDrug
P08684 DB01591 Solifenacin SmallMoleculeDrug
P08684 DB01595 Nitrazepam SmallMoleculeDrug
P08684 DB01601 Lopinavir SmallMoleculeDrug
P08684 DB01609 Deferasirox SmallMoleculeDrug
P08684 DB01621 Pipotiazine SmallMoleculeDrug
P08684 DB01628 Etoricoxib SmallMoleculeDrug
P08684 DB01764 Dalfopristin SmallMoleculeDrug
P08684 DB02701 Nicotinamide SmallMoleculeDrug
P08684 DB04572 Thiotepa SmallMoleculeDrug
P08684 DB04574 Estropipate SmallMoleculeDrug
P08684 DB04794 Bifonazole SmallMoleculeDrug
P08684 DB04835 Maraviroc SmallMoleculeDrug
P08684 DB04845 Ixabepilone SmallMoleculeDrug
P08684 DB04846 Celiprolol SmallMoleculeDrug
P08684 DB04855 Dronedarone SmallMoleculeDrug
P08684 DB04868 Nilotinib SmallMoleculeDrug
P08684 DB04871 Lorcaserin SmallMoleculeDrug
P08684 DB04908 Flibanserin SmallMoleculeDrug
P08684 DB04920 Clevidipine SmallMoleculeDrug
P08684 DB04930 Permethrin SmallMoleculeDrug
P08684 DB04938 Ospemifene SmallMoleculeDrug
P08684 DB04946 Iloperidone SmallMoleculeDrug
P08684 DB05039 Indacaterol SmallMoleculeDrug
P08684 DB05109 Trabectedin SmallMoleculeDrug
P08684 DB05239 Cobimetinib SmallMoleculeDrug
P08684 DB05271 Rotigotine SmallMoleculeDrug
P08684 DB05294 Vandetanib SmallMoleculeDrug
P08684 DB05521 Telaprevir SmallMoleculeDrug
P08684 DB05676 Apremilast SmallMoleculeDrug
P08684 DB05773 ado-trastuzumab emtansine SmallMoleculeDrug
P08684 DB05812 Abiraterone SmallMoleculeDrug
P08684 DB06016 Cariprazine SmallMoleculeDrug
P08684 DB06144 Sertindole SmallMoleculeDrug
P08684 DB06148 Mianserin SmallMoleculeDrug
P08684 DB06155 Rimonabant SmallMoleculeDrug
P08684 DB06201 Rufinamide SmallMoleculeDrug
P08684 DB06203 Alogliptin SmallMoleculeDrug
P08684 DB06207 Silodosin SmallMoleculeDrug
P08684 DB06209 Prasugrel SmallMoleculeDrug
P08684 DB06212 Tolvaptan SmallMoleculeDrug
P08684 DB06216 Asenapine SmallMoleculeDrug
P08684 DB06228 Rivaroxaban SmallMoleculeDrug
P08684 DB06237 Avanafil SmallMoleculeDrug
P08684 DB06267 Udenafil SmallMoleculeDrug
P08684 DB06268 Sitaxentan SmallMoleculeDrug
P08684 DB06282 Levocetirizine SmallMoleculeDrug
P08684 DB06287 Temsirolimus SmallMoleculeDrug
P08684 DB06290 Simeprevir SmallMoleculeDrug
P08684 DB06292 Dapagliflozin SmallMoleculeDrug
P08684 DB06335 Saxagliptin SmallMoleculeDrug
P08684 DB06403 Ambrisentan SmallMoleculeDrug
P08684 DB06413 Armodafinil SmallMoleculeDrug
P08684 DB06414 Etravirine SmallMoleculeDrug
P08684 DB06589 Pazopanib SmallMoleculeDrug
P08684 DB06603 Panobinostat SmallMoleculeDrug
P08684 DB06605 Apixaban SmallMoleculeDrug
P08684 DB06616 Bosutinib SmallMoleculeDrug
P08684 DB06626 Axitinib SmallMoleculeDrug
P08684 DB06636 Isavuconazonium SmallMoleculeDrug
P08684 DB06684 Vilazodone SmallMoleculeDrug
P08684 DB06697 Artemether SmallMoleculeDrug
P08684 DB06700 Desvenlafaxine SmallMoleculeDrug
P08684 DB06702 Fesoterodine SmallMoleculeDrug
P08684 DB06708 Lumefantrine SmallMoleculeDrug
P08684 DB06710 Methyltestosterone SmallMoleculeDrug
P08684 DB06712 Nilvadipine SmallMoleculeDrug
P08684 DB06738 Ketobemidone SmallMoleculeDrug
P08684 DB06742 Ambroxol SmallMoleculeDrug
P08684 DB06770 Benzyl alcohol SmallMoleculeDrug
P08684 DB06772 Cabazitaxel SmallMoleculeDrug
P08684 DB06774 Capsaicin SmallMoleculeDrug
P08684 DB06777 Chenodeoxycholic acid SmallMoleculeDrug
P08684 DB08439 Parecoxib SmallMoleculeDrug
P08684 DB08811 Tofisopam SmallMoleculeDrug
P08684 DB08815 Lurasidone SmallMoleculeDrug
P08684 DB08816 Ticagrelor SmallMoleculeDrug
P08684 DB08820 Ivacaftor SmallMoleculeDrug
P08684 DB08827 Lomitapide SmallMoleculeDrug
P08684 DB08828 Vismodegib SmallMoleculeDrug
P08684 DB08864 Rilpivirine SmallMoleculeDrug
P08684 DB08865 Crizotinib SmallMoleculeDrug
P08684 DB08866 Estradiol valerate/Dienogest SmallMoleculeDrug
P08684 DB08867 Ulipristal SmallMoleculeDrug
P08684 DB08868 Fingolimod SmallMoleculeDrug
P08684 DB08870 Brentuximab vedotin BiotechDrug
P08684 DB08873 Boceprevir SmallMoleculeDrug
P08684 DB08875 Cabozantinib SmallMoleculeDrug
P08684 DB08877 Ruxolitinib SmallMoleculeDrug
P08684 DB08881 Vemurafenib SmallMoleculeDrug
P08684 DB08882 Linagliptin SmallMoleculeDrug
P08684 DB08883 Perampanel SmallMoleculeDrug
P08684 DB08893 Mirabegron SmallMoleculeDrug
P08684 DB08895 Tofacitinib SmallMoleculeDrug
P08684 DB08896 Regorafenib SmallMoleculeDrug
P08684 DB08899 Enzalutamide SmallMoleculeDrug
P08684 DB08901 Ponatinib SmallMoleculeDrug
P08684 DB08903 Bedaquiline SmallMoleculeDrug
P08684 DB08906 Fluticasone furoate SmallMoleculeDrug
P08684 DB08907 Canagliflozin SmallMoleculeDrug
P08684 DB08910 Pomalidomide SmallMoleculeDrug
P08684 DB08911 Trametinib SmallMoleculeDrug
P08684 DB08912 Dabrafenib SmallMoleculeDrug
P08684 DB08918 Levomilnacipran SmallMoleculeDrug
P08684 DB08930 Dolutegravir SmallMoleculeDrug
P08684 DB08932 MACITENTAN SmallMoleculeDrug
P08684 DB08933 Luliconazole SmallMoleculeDrug
P08684 DB09026 Aliskiren SmallMoleculeDrug
P08684 DB09039 Eliglustat SmallMoleculeDrug
P08684 DB09049 Naloxegol SmallMoleculeDrug
P08684 DB09053 Ibrutinib SmallMoleculeDrug
P08684 DB09054 Idelalisib SmallMoleculeDrug
P08684 DB09068 Vortioxetine SmallMoleculeDrug
P08684 DB09073 Palbociclib SmallMoleculeDrug
P08684 DB09074 Olaparib SmallMoleculeDrug
P08684 DB09078 Lenvatinib SmallMoleculeDrug
P08684 DB09082 Vilanterol SmallMoleculeDrug
P08684 DB09083 Ivabradine SmallMoleculeDrug
P08684 DB09101 Elvitegravir SmallMoleculeDrug
P08684 DB09102 Daclatasvir SmallMoleculeDrug
P08684 DB09128 Brexpiprazole SmallMoleculeDrug
P08684 DB09143 Sonidegib SmallMoleculeDrug
P08684 DB09291 Rolapitant SmallMoleculeDrug
P08684 DB09330 Osimertinib SmallMoleculeDrug
P08684 DB09570 Ixazomib SmallMoleculeDrug
P08684 DB11362 Selexipag SmallMoleculeDrug
P08684 DB00199 Erythromycin SmallMoleculeDrug
P08684 DB00207 Azithromycin SmallMoleculeDrug
P08684 DB00951 Isoniazid SmallMoleculeDrug
P08684 DB01211 Clarithromycin SmallMoleculeDrug
P08684 DB01267 Paliperidone SmallMoleculeDrug

External Links

ArrayExpress GO
ICGC GO
Cancer3D GO
COSMIC GO
NCG GO
TSGene GO
Tumor Gene Family of Databases GO
CCDB GO
G2SBC GO
Osteosarcoma Database GO
RCDB GO

ArrayExpress	GO
ICGC	GO
Cancer3D	GO
COSMIC	GO
NCG	GO
TSGene	GO
Tumor Gene Family of Databases	GO
CCDB	GO
G2SBC	GO
Osteosarcoma Database	GO
RCDB	GO